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  • Blackwell Publishing Ltd  (51,396)
  • American Institute of Physics (AIP)  (46,193)
  • American Association for the Advancement of Science (AAAS)
  • American Association of Petroleum Geologists (AAPG)
  • 2020-2022  (9)
  • 2005-2009  (14,058)
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  • 1
    Publication Date: 2021-06-28
    Description: Efforts to collaboratively manage the risk of flooding are ultimately based on individuals learning about risks, the decision process, and the effectiveness of decisions made in prior situations. This article argues that much can be learned about a governance setting by explicitly evaluating the relationships through which influential individuals and their immediate contacts receive and send information to one another. We define these individuals as “brokers,” and the networks that emerge from their interactions as “learning spaces.” The aim of this article is to develop strategies to identify and evaluate the properties of a broker's learning space that are indicative of a collaborative flood risk management arrangement. The first part of this article introduces a set of indicators, and presents strategies to employ this list so as to systematically identify brokers, and compare their learning spaces. The second part outlines the lessons from an evaluation that explored cases in two distinct flood risk management settings in Germany. The results show differences in the observed brokers' learning spaces. The contacts and interactions of the broker in Baden‐Württemberg imply a collaborative setting. In contrast, learning space of the broker in North Rhine‐Westphalia lacks the same level of diversity and polycentricity.
    Description: Deutsche Forschungsgemeinschaft http://dx.doi.org/10.13039/501100001659
    Description: MWK Baden‐Württemberg
    Keywords: 333.91 ; brokerage ; collaborative water governance ; comanagement ; comparative analysis ; social networks
    Type: article
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  • 2
    Publication Date: 2021-07-04
    Description: Most common machine learning (ML) algorithms usually work well on balanced training sets, that is, datasets in which all classes are approximately represented equally. Otherwise, the accuracy estimates may be unreliable and classes with only a few values are often misclassified or neglected. This is known as a class imbalance problem in machine learning and datasets that do not meet this criterion are referred to as imbalanced data. Most datasets of soil classes are, therefore, imbalanced data. One of our main objectives is to compare eight resampling strategies that have been developed to counteract the imbalanced data problem. We compared the performance of five of the most common ML algorithms with the resampling approaches. The highest increase in prediction accuracy was achieved with SMOTE (the synthetic minority oversampling technique). In comparison to the baseline prediction on the original dataset, we achieved an increase of about 10, 20 and 10% in the overall accuracy, kappa index and F‐score, respectively. Regarding the ML approaches, random forest (RF) showed the best performance with an overall accuracy, kappa index and F‐score of 66, 60 and 57%, respectively. Moreover, the combination of RF and SMOTE improved the accuracy of the individual soil classes, compared to RF trained on the original dataset and allowed better prediction of soil classes with a low number of samples in the corresponding soil profile database, in our case for Chernozems. Our results show that balancing existing soil legacy data using synthetic sampling strategies can significantly improve the prediction accuracy in digital soil mapping (DSM). Highlights Spatial distribution of soil classes in Iran can be predicted using machine learning (ML) algorithms. The synthetic minority oversampling technique overcomes the drawback of imbalanced and highly biased soil legacy data. When combining a random forest model with synthetic sampling strategies the prediction accuracy of the soil model improves significantly. The resulting new soil map of Iran has a much higher spatial resolution compared to existing maps and displays new soil classes that have not yet been mapped in Iran.
    Description: Alexander von Humboldt‐Stiftung http://dx.doi.org/10.13039/100005156
    Description: German Research Foundation http://dx.doi.org/10.13039/501100001659
    Description: Soil and Water Research Institute, Agricultural Research, Education and Extension Organization, Karaj, Iran
    Keywords: 631.4 ; covariates ; imbalanced data ; machine learning ; random forest ; soil legacy data
    Type: article
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  • 3
    Publication Date: 2021-06-16
    Description: The application of biochar to agricultural soils to increase nutrient availability, crop production and carbon sequestration has gained increasing interest but data from field experiments on temperate, marginal soils are still under‐represented. In the current study, biochar, produced from organic residues (digestates) from a biogas plant, was applied with and without digestates at low (3.4 t ha−1) and intermediate (17.1 t ha−1) rates to two acidic and sandy soils in northern Germany that are used for corn (Zea mays L.) production. Soil nutrient availability, crop yields, microbial biomass and carbon dioxide (CO2) emissions from heterotrophic respiration were measured over two consecutive years. The effects of biochar application depended on the intrinsic properties of the two tested soils and the biochar application rates. Although the soils at the fallow site, with initially low nutrient concentrations, showed a significant increase in pH, soil nutrients and crop yield after low biochar application rates, a similar response was found at the cornfield site only after application of substantially larger amounts of biochar. The effect of a single dose of biochar at the beginning of the experiment diminished over time but was still detectable after 2 years. Whereas plant available nutrient concentrations increased after biochar application, the availability of potentially phytotoxic trace elements (Zn, Pb, Cd, Cr) decreased significantly, and although slight increases in microbial biomass carbon and heterotrophic CO2 fluxes were observed after biochar application, they were mostly not significant. The results indicate that the application of relatively small amounts of biochar could have positive effects on plant available nutrients and crop yields of marginal arable soils and may decrease the need for mineral fertilizers while simultaneously increasing the sequestration of soil organic carbon. Highlights A low rate of biochar increased plant available nutrients and crop yield on marginal soils. Biochar application reduced the availability of potentially harmful trace elements. Heterotrophic respiration showed no clear response to biochar application. Biochar application may reduce fertilizer need and increase carbon sequestration on marginal soils.
    Description: German Academic Exchange Service http://dx.doi.org/10.13039/501100001655
    Description: Institute Strategic Programme grants, “Soils to Nutrition”
    Keywords: 631.4 ; black carbon ; carbon sequestration ; corn ; digestate ; heterotrophic respiration ; marginal soils ; microbial biomass
    Type: article
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  • 4
    Publication Date: 2021-06-27
    Description: Social inequalities lead to flood resilience inequalities across social groups, a topic that requires improved documentation and understanding. The objective of this paper is to attend to these differences by investigating self‐stated flood recovery across genders in Vietnam as a conceptual replication of earlier results from Germany. This study employs a regression‐based analysis of 1,010 respondents divided between a rural coastal and an urban community in Thua Thien‐Hue province. The results highlight an important set of recovery process‐related variables. The set of relevant variables is similar across genders in terms of inclusion and influence, and includes age, social capital, internal and external support after a flood, perceived severity of previous flood impacts, and the perception of stress‐resilience. However, women were affected more heavily by flooding in terms of longer recovery times, which should be accounted for in risk management. Overall, the studied variables perform similarly in Vietnam and Germany. This study, therefore, conceptually replicates previous results suggesting that women display slightly slower recovery levels as well as that psychological variables influence recovery rates more than adverse flood impacts. This provides an indication of the results' potentially robust nature due to the different socio‐environmental contexts in Germany and Vietnam.
    Keywords: 333.7 ; flood recovery ; resilience ; societal equity ; vulnerability
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  • 5
    Publication Date: 2021-07-05
    Description: Nitrogen (N) fertilization is the major contributor to nitrous oxide (N2O) emissions from agricultural soil, especially in post‐harvest seasons. This study was carried out to investigate whether ryegrass serving as cover crop affects soil N2O emissions and denitrifier community size. A microcosm experiment was conducted with soil planted with perennial ryegrass (Lolium perenne L.) and bare soil, each with four levels of N fertilizer (0, 5, 10 and 20 g N m−2; applied as calcium ammonium nitrate). The closed‐chamber approach was used to measure soil N2O fluxes. Real‐time PCR was used to estimate the biomass of bacteria and fungi and the abundance of genes involved in denitrification in soil. The results showed that the presence of ryegrass decreased the nitrate content in soil. Cumulative N2O emissions of soil with grass were lower than in bare soil at 5 and 10 g N m−2. Fertilization levels did not affect the abundance of soil bacteria and fungi. Soil with grass showed greater abundances of bacteria and fungi, as well as microorganisms carrying narG, napA, nirK, nirS and nosZ clade I genes. It is concluded that ryegrass serving as a cover crop holds the potential to mitigate soil N2O emissions in soils with moderate or high NO3− concentrations. This highlights the importance of cover crops for the reduction of N2O emissions from soil, particularly following N fertilization. Future research should explore the full potential of ryegrass to reduce soil N2O emissions under field conditions as well as in different soils. Highlights This study was to investigate whether ryegrass serving as cover crop affects soil N2O emissions and denitrifier community size; Plant reduced soil N substrates on one side, but their root exudates stimulated denitrification on the other side; N2O emissions were lower in soil with grass than bare soil at medium fertilizer levels, and growing grass stimulated the proliferation of almost all the denitrifying bacteria except nosZ clade II; Ryegrass serving as a cover crop holds the potential to mitigate soil N2O emissions.
    Description: China Scholarship Council http://dx.doi.org/10.13039/501100004543
    Description: The National Science Project for University of Anhui Province
    Keywords: 551.9 ; 631.4 ; denitrification ; perennial ryegrass (Lolium perenne L.) ; soil bacteria ; soil CO2 emissions ; soil N2O emissions
    Type: article
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  • 6
    Publication Date: 2021-07-04
    Description: High‐performance numerical codes are an indispensable tool for hydrogeologists when modeling subsurface flow and transport systems. But as they are written in compiled languages, like C/C++ or Fortran, established software packages are rarely user‐friendly, limiting a wider adoption of such tools. OpenGeoSys (OGS), an open‐source, finite‐element solver for thermo‐hydro‐mechanical–chemical processes in porous and fractured media, is no exception. Graphical user interfaces may increase usability, but do so at a dramatic reduction of flexibility and are difficult or impossible to integrate into a larger workflow. Python offers an optimal trade‐off between these goals by providing a highly flexible, yet comparatively user‐friendly environment for software applications. Hence, we introduce ogs5py, a Python‐API for the OpenGeoSys 5 scientific modeling package. It provides a fully Python‐based representation of an OGS project, a large array of convenience functions for users to interact with OGS and connects OGS to the scientific and computational environment of Python.
    Description: German Federal Environmental Foundation http://dx.doi.org/10.13039/100007636
    Description: Deutsche Forschungsgemeinschaft http://dx.doi.org/10.13039/501100001659
    Keywords: 551.49 ; hydrogeology ; subsurface flow ; modeling ; software
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  • 7
    Publication Date: 2021-06-27
    Description: Transport processes that lead to exchange of mass between surface water and groundwater play a significant role for the ecological functioning of aquatic systems, for hydrological processes and for biogeochemical transformations. In this study, we present a novel integral modeling approach for flow and transport at the sediment–water interface. The model allows us to simultaneously simulate turbulent surface and subsurface flow and transport with the same conceptual approach. For this purpose, a conservative transport equation was implemented to an existing approach that uses an extended version of the Navier–Stokes equations. Based on previous flume studies which investigated the spreading of a dye tracer under neutral, losing and gaining flow conditions the new solver is validated. Tracer distributions of the experiments are in close agreement with the simulations. The simulated flow paths are significantly affected by in‐ and outflowing groundwater flow. The highest velocities within the sediment are found for losing condition, which leads to shorter residence times compared to neutral and gaining conditions. The largest extent of the hyporheic exchange flow is observed under neutral condition. The new solver can be used for further examinations of cases that are not suitable for the conventional coupled models, for example, if Reynolds numbers are larger than 10. Moreover, results gained with the integral solver provide high‐resolution information on pressure and velocity distributions at the rippled streambed, which can be used to improve flow predictions. This includes the extent of hyporheic exchange under varying ambient groundwater flow conditions.
    Description: Technische Universität Berlin, Germany
    Description: German Research Foundation http://dx.doi.org/10.13039/501100001659
    Keywords: 551.4 ; aquatic systems ; sediment-water interface ; transport model
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  • 8
    Publication Date: 2021-07-05
    Description: Sustainable arable cropping relies on repeated liming. Yet, the associated increase in soil pH can reduce the availability of iron (Fe) to plants. We hypothesized that repeated liming, but not pedogenic processes such as lessivage (i.e., translocation of clay particles), alters the Fe cycle in Luvisol soil, thereby affecting Fe isotope composition in soils and crops. Hence, we analysed Fe concentrations and isotope compositions in soil profiles and winter rye from the long‐term agricultural experimental site in Berlin‐Dahlem, Germany, where a controlled liming trial with three field replicates per treatment has been conducted on Albic Luvisols since 1923. Heterogeneity in subsoil was observed at this site for Fe concentration but not for Fe isotope composition. Lessivage had not affected Fe isotope composition in the soil profiles. The results also showed that almost 100 years of liming lowered the concentration of the HCl‐extractable Fe that was potentially available for plant uptake in the surface soil (0–15 cm) from 1.03 (standard error (SE) 0.03) to 0.94 (SE 0.01) g kg−1. This HCl‐extractable Fe pool contained isotopically lighter Fe (δ56Fe = −0.05 to −0.29‰) than the bulk soil (δ56Fe = −0.08 to 0.08‰). However, its Fe isotope composition was not altered by the long‐term lime application. Liming resulted in relatively lower Fe concentrations in the roots of winter rye. In addition, liming led to a heavier Fe isotope composition of the whole plants compared with those grown in the non‐limed plots (δ56FeWholePlant_ + Lime = −0.12‰, SE 0.03 vs. δ56FeWholePlant_‐Lime = −0.21‰, SE 0.01). This suggests that the elevated soil pH (increased by one unit due to liming) promoted the Fe uptake strategy through complexation of Fe(III) from the rhizosphere, which favoured heavier Fe isotopes. Overall, the present study showed that liming and a related increase in pH did not affect the Fe isotope compositions of the soil, but may influence the Fe isotope composition of plants grown in the soil if they alter their Fe uptake strategy upon the change of Fe availability. Highlights Fe concentrations and stocks, but not Fe isotope compositions, were more heterogeneous in subsoil than in topsoil. Translocation of clay minerals did not result in Fe isotope fractionation in the soil profile of a Luvisol. Liming decreased Fe availability in topsoil, but did not affect its δ56Fe values. Uptake of heavier Fe isotopes by graminaceous crops was more pronounced at elevated pH.
    Description: Bundesministerium für Bildung und Forschung http://dx.doi.org/10.13039/501100002347
    Keywords: 551.9 ; liming ; plant‐available Fe pool in soil ; winter rye ; δ56Fe
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  • 9
    Publication Date: 2021-09-29
    Description: Coping with the growing impacts of flooding in EU countries, a paradigm shift in flood management can be observed, moving from safety‐based towards risk‐based approaches and holistic perspectives. Flood resilience is a common denominator of most of the approaches. In this article, we present the ‘Flood Resilience Rose’ (FRR), a management tool to promote harmonised action towards flood resilience in European regions and beyond. The FRR is a result of a two‐step process. First, based on scientific concepts as well as analysis of relevant policy documents, we identified three ‘levels of operation’. The first level refers to the EU Floods Directive and an extended multi‐layer safety approach, comprising the four different layers of protection, prevention, preparedness and recovery, and related measures to be taken. This level is not independent but depends both on the institutional (second level) and the wider (third level) context. Second, we used surveys, semi‐structured interviews and group discussions during workshops with experts from Belgium, Denmark, Germany, the Netherlands and the United Kingdom to validate the definitions and the FRR's practical relevance. The presented FRR is thus the result of rigorous theoretical and practical consideration and provides a tool capable to strengthen flood risk management practice.
    Description: European Regional Development Fund http://dx.doi.org/10.13039/501100008530
    Keywords: 551.48 ; flood defence measures ; governance and institutions ; integrated flood risk management ; resilience
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  • 10
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    American Association for the Advancement of Science (AAAS)
    Publication Date: 2009-12-19
    Description: 〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Dovidio, John F -- New York, N.Y. -- Science. 2009 Dec 18;326(5960):1641-2. doi: 10.1126/science.1184231.〈br /〉〈span class="detail_caption"〉Author address: 〈/span〉Department of Psychology, Yale University, New Haven, CT 06520-8205, USA. john.dovidio@yale.edu〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/20019277" target="_blank"〉PubMed〈/a〉
    Keywords: *African Continental Ancestry Group ; Cues ; *European Continental Ancestry Group ; Humans ; *Nonverbal Communication ; *Prejudice ; *Social Behavior ; *Television ; United States
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
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  • 11
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    American Association for the Advancement of Science (AAAS)
    Publication Date: 2009-01-03
    Description: Video games have enormous mass appeal, reaching audiences in the hundreds of thousands to millions. They also embed many pedagogical practices known to be effective in other environments. This article reviews the sparse but encouraging data on learning outcomes for video games in science, technology, engineering, and math (STEM) disciplines, then reviews the infrastructural obstacles to wider adoption of this new medium.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Mayo, Merrilea J -- New York, N.Y. -- Science. 2009 Jan 2;323(5910):79-82. doi: 10.1126/science.1166900.〈br /〉〈span class="detail_caption"〉Author address: 〈/span〉Ewing Marion Kauffman Foundation, 4801 Rockhill Road, Kansas City, MO 64110 USA. mmayo@kauffman.org〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/19119223" target="_blank"〉PubMed〈/a〉
    Keywords: Adolescent ; Child ; *Educational Technology/economics/standards ; Engineering/*education ; Humans ; *Learning ; *Mathematical Concepts ; Problem Solving ; Science/*education ; *Video Games/economics/standards
    Print ISSN: 0036-8075
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    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
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  • 12
    Publication Date: 2009-02-21
    Description: 〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Kintisch, Eli -- New York, N.Y. -- Science. 2009 Feb 20;323(5917):992-3. doi: 10.1126/science.323.5917.992.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/19229002" target="_blank"〉PubMed〈/a〉
    Keywords: Biomedical Research/*economics ; Budgets/legislation & jurisprudence ; National Institutes of Health (U.S.)/*economics ; Research Support as Topic/*legislation & jurisprudence ; United States ; United States Government Agencies/*economics
    Print ISSN: 0036-8075
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    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
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  • 13
    Publication Date: 2009-05-09
    Description: Access to genuine multipartite entanglement of quantum states enables advances in quantum information science and also contributes to the understanding of strongly correlated quantum systems. We report the detection and characterization of heralded entanglement in a multipartite quantum state composed of four spatially distinct optical modes that share one photon, a so-called W state. By randomizing the relative phase between bipartite components of the W state, we observed the transitions from four- to three- to two-mode entanglement with increasing phase noise. These observations are possible for our system because our entanglement verification protocol makes use of quantum uncertainty relations to detect the entangled states that span the Hilbert space of interest.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Papp, Scott B -- Choi, Kyung Soo -- Deng, Hui -- Lougovski, Pavel -- van Enk, S J -- Kimble, H J -- New York, N.Y. -- Science. 2009 May 8;324(5928):764-8. doi: 10.1126/science.1172260.〈br /〉〈span class="detail_caption"〉Author address: 〈/span〉Norman Bridge Laboratory of Physics 12-33, California Institute of Technology, Pasadena, CA 91125, USA.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/19423821" target="_blank"〉PubMed〈/a〉
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    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
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  • 14
    Publication Date: 2009-03-28
    Description: The sensitivity of both nuclear magnetic resonance spectroscopy and magnetic resonance imaging is very low because the detected signal strength depends on the small population difference between spin states even in high magnetic fields. Hyperpolarization methods can be used to increase this difference and thereby enhance signal strength. This has been achieved previously by incorporating the molecular spin singlet para-hydrogen into hydrogenation reaction products. We show here that a metal complex can facilitate the reversible interaction of para-hydrogen with a suitable organic substrate such that up to an 800-fold increase in proton, carbon, and nitrogen signal strengths are seen for the substrate without its hydrogenation. These polarized signals can be selectively detected when combined with methods that suppress background signals.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Adams, Ralph W -- Aguilar, Juan A -- Atkinson, Kevin D -- Cowley, Michael J -- Elliott, Paul I P -- Duckett, Simon B -- Green, Gary G R -- Khazal, Iman G -- Lopez-Serrano, Joaquin -- Williamson, David C -- Biotechnology and Biological Sciences Research Council/United Kingdom -- Medical Research Council/United Kingdom -- New York, N.Y. -- Science. 2009 Mar 27;323(5922):1708-11. doi: 10.1126/science.1168877.〈br /〉〈span class="detail_caption"〉Author address: 〈/span〉Department of Chemistry, University of York, Heslington, York, YO10 5DD, UK.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/19325111" target="_blank"〉PubMed〈/a〉
    Keywords: Carbon/analysis ; Hydrogen/*chemistry ; Iridium/chemistry ; Ligands ; Magnetic Resonance Imaging ; *Magnetic Resonance Spectroscopy ; Niacinamide/chemistry ; Nitrogen/analysis ; Protons ; Pyridines/chemistry ; Sensitivity and Specificity
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  • 15
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    American Association for the Advancement of Science (AAAS)
    Publication Date: 2009-11-11
    Description: 〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Service, Robert F -- New York, N.Y. -- Science. 2009 Oct 23;326(5952):516-7. doi: 10.1126/science.326_516.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/19900876" target="_blank"〉PubMed〈/a〉
    Keywords: *Agriculture ; *Biofuels ; *Ethanol ; Eutrophication ; Poaceae/growth & development ; United States ; *Water ; Water Supply ; Zea mays/growth & development
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    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
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  • 16
    Publication Date: 2009-04-18
    Description: 〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Mayr, Nina A -- Lo, Simon S -- Wang, Jian Z -- Yuh, William T C -- New York, N.Y. -- Science. 2009 Apr 17;324(5925):334-5. doi: 10.1126/science.324.5925.334c.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/19372412" target="_blank"〉PubMed〈/a〉
    Keywords: *Education, Medical, Graduate ; Humans ; Radiation Oncology/*education ; Teaching/*methods
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    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
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  • 17
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    American Association for the Advancement of Science (AAAS)
    Publication Date: 2009-06-13
    Description: 〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Parfitt, Tom -- New York, N.Y. -- Science. 2009 Jun 12;324(5933):1382-4. doi: 10.1126/science.324_1382a.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/19520934" target="_blank"〉PubMed〈/a〉
    Keywords: Arctic Regions ; Cold Climate ; Expeditions ; History, 20th Century ; History, 21st Century ; Ice Cover ; Internationality ; Oceanography/*history ; Politics ; Russia
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    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
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  • 18
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    American Association for the Advancement of Science (AAAS)
    Publication Date: 2009-07-25
    Description: 〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Dreyfus, David H -- New York, N.Y. -- Science. 2009 Jul 24;325(5939):392-3. doi: 10.1126/science.325_392c.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/19628838" target="_blank"〉PubMed〈/a〉
    Keywords: Antibody Formation ; DNA Viruses/*physiology ; Genes, RAG-1 ; Herpesviridae/physiology ; Immune System/*physiology
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    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
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  • 19
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    American Association for the Advancement of Science (AAAS)
    Publication Date: 2009-05-23
    Description: 〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Havlin, Shlomo -- New York, N.Y. -- Science. 2009 May 22;324(5930):1023-4. doi: 10.1126/science.1174658.〈br /〉〈span class="detail_caption"〉Author address: 〈/span〉Physics Department, Bar-Ilan University, Ramat-Gan, 52900 Israel. havlin@ophir.ph.biu.ac.il〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/19460993" target="_blank"〉PubMed〈/a〉
    Keywords: *Cell Phones ; *Computer Security ; Humans
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    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
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  • 20
    Publication Date: 2009-08-29
    Description: Coat color and type are essential characteristics of domestic dog breeds. Although the genetic basis of coat color has been well characterized, relatively little is known about the genes influencing coat growth pattern, length, and curl. We performed genome-wide association studies of more than 1000 dogs from 80 domestic breeds to identify genes associated with canine fur phenotypes. Taking advantage of both inter- and intrabreed variability, we identified distinct mutations in three genes, RSPO2, FGF5, and KRT71 (encoding R-spondin-2, fibroblast growth factor-5, and keratin-71, respectively), that together account for most coat phenotypes in purebred dogs in the United States. Thus, an array of varied and seemingly complex phenotypes can be reduced to the combinatorial effects of only a few genes.〈br /〉〈br /〉〈a href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2897713/" target="_blank"〉〈img src="https://static.pubmed.gov/portal/portal3rc.fcgi/4089621/img/3977009" border="0"〉〈/a〉   〈a href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2897713/" target="_blank"〉This paper as free author manuscript - peer-reviewed and accepted for publication〈/a〉〈br /〉〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Cadieu, Edouard -- Neff, Mark W -- Quignon, Pascale -- Walsh, Kari -- Chase, Kevin -- Parker, Heidi G -- Vonholdt, Bridgett M -- Rhue, Alison -- Boyko, Adam -- Byers, Alexandra -- Wong, Aaron -- Mosher, Dana S -- Elkahloun, Abdel G -- Spady, Tyrone C -- Andre, Catherine -- Lark, K Gordon -- Cargill, Michelle -- Bustamante, Carlos D -- Wayne, Robert K -- Ostrander, Elaine A -- 1R01GM83606/GM/NIGMS NIH HHS/ -- GM063056/GM/NIGMS NIH HHS/ -- R01 GM063056/GM/NIGMS NIH HHS/ -- R01 GM063056-09/GM/NIGMS NIH HHS/ -- Intramural NIH HHS/ -- New York, N.Y. -- Science. 2009 Oct 2;326(5949):150-3. doi: 10.1126/science.1177808. Epub 2009 Aug 27.〈br /〉〈span class="detail_caption"〉Author address: 〈/span〉National Human Genome Research Institute, National Institutes of Health, Bethesda, MD 20892, USA.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/19713490" target="_blank"〉PubMed〈/a〉
    Keywords: 3' Untranslated Regions ; Animals ; Dogs/*genetics ; Fibroblast Growth Factor 5/*genetics ; Genome-Wide Association Study ; *Hair/anatomy & histology/growth & development ; Haplotypes ; Keratins, Hair-Specific/*genetics ; Lod Score ; Molecular Sequence Data ; Mutation ; Oligonucleotide Array Sequence Analysis ; Phenotype ; *Polymorphism, Single Nucleotide ; Sequence Analysis, DNA ; Thrombospondins/*genetics ; United States
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  • 21
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    American Association for the Advancement of Science (AAAS)
    Publication Date: 2009-10-10
    Description: 〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Ahmed, Kamran -- Ashrafian, Hutan -- New York, N.Y. -- Science. 2009 Oct 9;326(5950):227. doi: 10.1126/science.326_227a.〈br /〉〈span class="detail_caption"〉Author address: 〈/span〉Department of Biosurgery and Surgical Technology, Imperial College London, London W2 1NY, UK. k.ahmed@imperial.ac.uk〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/19815754" target="_blank"〉PubMed〈/a〉
    Keywords: Biomedical Technology/*education ; *Education, Medical, Continuing ; *Education, Medical, Graduate
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  • 22
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    American Association for the Advancement of Science (AAAS)
    Publication Date: 2009-01-03
    Description: 〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Von Bartheld, Christopher S -- Collin, Shaun P -- Gunturkun, Onur -- New York, N.Y. -- Science. 2009 Jan 2;323(5910):36-7. doi: 10.1126/science.323.5910.36c.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/19119199" target="_blank"〉PubMed〈/a〉
    Keywords: *Bibliometrics ; Information Storage and Retrieval/*statistics & numerical data ; Internet ; Periodicals as Topic/*statistics & numerical data ; Publishing/*statistics & numerical data
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  • 23
    Publication Date: 2009-09-12
    Description: RNA interference (RNAi), a gene-silencing pathway triggered by double-stranded RNA, is conserved in diverse eukaryotic species but has been lost in the model budding yeast Saccharomyces cerevisiae. Here, we show that RNAi is present in other budding yeast species, including Saccharomyces castellii and Candida albicans. These species use noncanonical Dicer proteins to generate small interfering RNAs, which mostly correspond to transposable elements and Y' subtelomeric repeats. In S. castellii, RNAi mutants are viable but have excess Y' messenger RNA levels. In S. cerevisiae, introducing Dicer and Argonaute of S. castellii restores RNAi, and the reconstituted pathway silences endogenous retrotransposons. These results identify a previously unknown class of Dicer proteins, bring the tool of RNAi to the study of budding yeasts, and bring the tools of budding yeast to the study of RNAi.〈br /〉〈br /〉〈a href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3786161/" target="_blank"〉〈img src="https://static.pubmed.gov/portal/portal3rc.fcgi/4089621/img/3977009" border="0"〉〈/a〉   〈a href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3786161/" target="_blank"〉This paper as free author manuscript - peer-reviewed and accepted for publication〈/a〉〈br /〉〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Drinnenberg, Ines A -- Weinberg, David E -- Xie, Kathleen T -- Mower, Jeffrey P -- Wolfe, Kenneth H -- Fink, Gerald R -- Bartel, David P -- GM0305010/GM/NIGMS NIH HHS/ -- GM040266/GM/NIGMS NIH HHS/ -- GM067031/GM/NIGMS NIH HHS/ -- R01 GM067031/GM/NIGMS NIH HHS/ -- Howard Hughes Medical Institute/ -- New York, N.Y. -- Science. 2009 Oct 23;326(5952):544-50. doi: 10.1126/science.1176945. Epub 2009 Sep 10.〈br /〉〈span class="detail_caption"〉Author address: 〈/span〉Whitehead Institute for Biomedical Research, 9 Cambridge Center, Cambridge, MA 02142, USA.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/19745116" target="_blank"〉PubMed〈/a〉
    Keywords: Fungal Proteins/genetics/metabolism ; Gene Expression Profiling ; Genes, Fungal ; Genetic Loci ; Mutation ; Open Reading Frames ; *RNA Interference ; RNA, Double-Stranded/genetics/metabolism ; RNA, Fungal/genetics/metabolism ; RNA, Messenger/genetics/metabolism ; RNA, Small Interfering/genetics/*metabolism ; Repetitive Sequences, Nucleic Acid ; Retroelements ; Ribonuclease III/genetics/metabolism ; Saccharomyces/*genetics/metabolism ; Saccharomyces cerevisiae/*genetics/metabolism ; Saccharomyces cerevisiae Proteins/genetics/metabolism ; Saccharomycetales/*genetics/metabolism ; Sequence Analysis, RNA ; Transcription, Genetic ; Transformation, Genetic
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  • 24
    Publication Date: 2009-02-21
    Description: Generating laterally ordered, ultradense, macroscopic arrays of nanoscopic elements will revolutionize the microelectronic and storage industries. We used faceted surfaces of commercially available sapphire wafers to guide the self-assembly of block copolymer microdomains into oriented arrays with quasi-long-range crystalline order over arbitrarily large wafer surfaces. Ordered arrays of cylindrical microdomains 3 nanometers in diameter, with areal densities in excess of 10 terabits per square inch, were produced. The sawtoothed substrate topography provides directional guidance to the self-assembly of the block copolymer, which is tolerant of surface defects, such as dislocations. The lateral ordering and lattice orientation of the single-grain arrays of microdomains are maintained over the entire surface. The approach described is parallel, applicable to different substrates and block copolymers, and opens a versatile route toward ultrahigh-density systems.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Park, Soojin -- Lee, Dong Hyun -- Xu, Ji -- Kim, Bokyung -- Hong, Sung Woo -- Jeong, Unyong -- Xu, Ting -- Russell, Thomas P -- New York, N.Y. -- Science. 2009 Feb 20;323(5917):1030-3. doi: 10.1126/science.1168108.〈br /〉〈span class="detail_caption"〉Author address: 〈/span〉Department of Polymer Science and Engineering, University of Massachusetts, Amherst, MA 01003, USA.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/19229031" target="_blank"〉PubMed〈/a〉
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  • 25
    Publication Date: 2009-09-05
    Description: 〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Service, Robert F -- New York, N.Y. -- Science. 2009 Sep 4;325(5945):1200. doi: 10.1126/science.325_1200a.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/19729635" target="_blank"〉PubMed〈/a〉
    Keywords: Algal Proteins/*metabolism/*pharmacology ; Animals ; Anti-HIV Agents/metabolism/pharmacology ; Antiviral Agents/*metabolism/*pharmacology ; Ebolavirus/drug effects ; HIV/drug effects ; Humans ; Lectins/*metabolism/*pharmacology ; Mannose/*metabolism ; Mice ; Microbial Sensitivity Tests ; Plant Lectins ; SARS Virus/drug effects ; Virus Diseases/drug therapy ; Viruses/*drug effects
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  • 26
    Publication Date: 2009-02-14
    Description: Flexible, stretchable, and spanning microelectrodes that carry signals from one circuit element to another are needed for many emerging forms of electronic and optoelectronic devices. We have patterned silver microelectrodes by omnidirectional printing of concentrated nanoparticle inks in both uniform and high-aspect ratio motifs with minimum widths of approximately 2 micrometers onto semiconductor, plastic, and glass substrates. The patterned microelectrodes can withstand repeated bending and stretching to large levels of strain with minimal degradation of their electrical properties. With this approach, wire bonding to fragile three-dimensional devices and spanning interconnects for solar cell and light-emitting diode arrays are demonstrated.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Ahn, Bok Y -- Duoss, Eric B -- Motala, Michael J -- Guo, Xiaoying -- Park, Sang-Il -- Xiong, Yujie -- Yoon, Jongseung -- Nuzzo, Ralph G -- Rogers, John A -- Lewis, Jennifer A -- New York, N.Y. -- Science. 2009 Mar 20;323(5921):1590-3. doi: 10.1126/science.1168375. Epub 2009 Feb 12.〈br /〉〈span class="detail_caption"〉Author address: 〈/span〉Frederick Seitz Materials Research Laboratory, University of Illinois at Urbana-Champaign, Urbana, IL 61801, USA.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/19213878" target="_blank"〉PubMed〈/a〉
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  • 27
    Publication Date: 2009-08-15
    Description: Microbes are incredibly abundant and diverse and are key to ecosystem functioning, yet relatively little is known about the ecological and evolutionary mechanisms that shape their distributions. Bacteriophages, viral parasites that lyse their bacterial hosts, exert intense and spatially varying selection pressures on bacteria and vice versa. We measured local adaptation of bacteria and their associated phages in a centimeter-scale soil population. We first demonstrate that a large proportion of bacteria is sensitive to locally occurring phages. We then show that sympatric phages (isolated from the same 2-gram soil samples as the bacteria) are more infective than are phages from samples some distance away. This study demonstrates the importance of biotic interactions for the small-scale spatial structuring of microbial genetic diversity in soil.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Vos, Michiel -- Birkett, Philip J -- Birch, Elizabeth -- Griffiths, Robert I -- Buckling, Angus -- New York, N.Y. -- Science. 2009 Aug 14;325(5942):833. doi: 10.1126/science.1174173.〈br /〉〈span class="detail_caption"〉Author address: 〈/span〉Department of Zoology, University of Oxford, Oxford OX1 3PS, UK. michiel.vos@nioo.knaw.nl〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/19679806" target="_blank"〉PubMed〈/a〉
    Keywords: *Adaptation, Physiological ; Bacteria/genetics/*virology ; Bacterial Physiological Phenomena ; Bacteriophages/genetics/*physiology ; Biological Evolution ; Ecosystem ; Genetic Variation ; Molecular Sequence Data ; Selection, Genetic ; *Soil Microbiology ; Stenotrophomonas/genetics/physiology/*virology ; Viral Plaque Assay
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    American Association for the Advancement of Science (AAAS)
    Publication Date: 2009-08-08
    Description: The key challenge for reactor engineering is to establish the scientifically based sustainable technologies necessary for meeting the future energy, environmental, and materials needs of the world. This goal requires advancing our scientific understanding of multiscale kinetic transport interactions to enable better reactor choice and to ensure higher reactor and process efficiencies.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Dudukovic, Milorad P -- New York, N.Y. -- Science. 2009 Aug 7;325(5941):698-701. doi: 10.1126/science.1174274.〈br /〉〈span class="detail_caption"〉Author address: 〈/span〉Chemical Reaction Engineering Laboratory, Department of Energy, Environmental and Chemical Engineering, Washington University, St. Louis, MO 63130, USA. dudu@wustl.edu〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/19661416" target="_blank"〉PubMed〈/a〉
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    American Association for the Advancement of Science (AAAS)
    Publication Date: 2009-08-08
    Description: 〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Kleindienst, Tadeusz E -- New York, N.Y. -- Science. 2009 Aug 7;325(5941):687-8. doi: 10.1126/science.1178324.〈br /〉〈span class="detail_caption"〉Author address: 〈/span〉National Exposure Research Laboratory, Office of Research and Development, U.S. EPA, Research Triangle Park, NC 27711, USA. kleindienst.tad@epa.gov〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/19661409" target="_blank"〉PubMed〈/a〉
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  • 30
    Publication Date: 2009-04-11
    Description: Genetic exchange has not been shown to be a mechanism underlying the extensive diversity of Leishmania parasites. We report here evidence that the invertebrate stages of Leishmania are capable of having a sexual cycle consistent with a meiotic process like that described for African trypanosomes. Hybrid progeny were generated that bore full genomic complements from both parents, but kinetoplast DNA maxicircles from one parent. Mating occurred only in the sand fly vector, and hybrids were transmitted to the mammalian host by sand fly bite. Genetic exchange likely contributes to phenotypic diversity in natural populations, and analysis of hybrid progeny will be useful for positional cloning of the genes controlling traits such as virulence, tissue tropism, and drug resistance.〈br /〉〈br /〉〈a href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2729066/" target="_blank"〉〈img src="https://static.pubmed.gov/portal/portal3rc.fcgi/4089621/img/3977009" border="0"〉〈/a〉   〈a href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2729066/" target="_blank"〉This paper as free author manuscript - peer-reviewed and accepted for publication〈/a〉〈br /〉〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Akopyants, Natalia S -- Kimblin, Nicola -- Secundino, Nagila -- Patrick, Rachel -- Peters, Nathan -- Lawyer, Phillip -- Dobson, Deborah E -- Beverley, Stephen M -- Sacks, David L -- A1020941/PHS HHS/ -- A1029646/PHS HHS/ -- R01 AI029646/AI/NIAID NIH HHS/ -- R01 AI029646-20/AI/NIAID NIH HHS/ -- Intramural NIH HHS/ -- New York, N.Y. -- Science. 2009 Apr 10;324(5924):265-8. doi: 10.1126/science.1169464.〈br /〉〈span class="detail_caption"〉Author address: 〈/span〉Department of Molecular Microbiology, Washington University School of Medicine, St. Louis, MO 63110, USA.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/19359589" target="_blank"〉PubMed〈/a〉
    Keywords: Animals ; Antiprotozoal Agents/pharmacology ; DNA, Kinetoplast/genetics ; DNA, Protozoan/analysis/genetics ; Drug Resistance ; Female ; Genes, Protozoan ; *Hybridization, Genetic ; Insect Vectors/*parasitology ; Leishmania major/drug effects/*genetics/*growth & development/pathogenicity ; Leishmaniasis, Cutaneous/parasitology ; Meiosis ; Mice ; Mice, Inbred BALB C ; Molecular Sequence Data ; Phenotype ; Phlebotomus/*parasitology ; Polymorphism, Single Nucleotide
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  • 31
    Publication Date: 2009-08-15
    Description: Sleep deprivation can impair human health and performance. Habitual total sleep time and homeostatic sleep response to sleep deprivation are quantitative traits in humans. Genetic loci for these traits have been identified in model organisms, but none of these potential animal models have a corresponding human genotype and phenotype. We have identified a mutation in a transcriptional repressor (hDEC2-P385R) that is associated with a human short sleep phenotype. Activity profiles and sleep recordings of transgenic mice carrying this mutation showed increased vigilance time and less sleep time than control mice in a zeitgeber time- and sleep deprivation-dependent manner. These mice represent a model of human sleep homeostasis that provides an opportunity to probe the effect of sleep on human physical and mental health.〈br /〉〈br /〉〈a href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2884988/" target="_blank"〉〈img src="https://static.pubmed.gov/portal/portal3rc.fcgi/4089621/img/3977009" border="0"〉〈/a〉   〈a href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2884988/" target="_blank"〉This paper as free author manuscript - peer-reviewed and accepted for publication〈/a〉〈br /〉〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉He, Ying -- Jones, Christopher R -- Fujiki, Nobuhiro -- Xu, Ying -- Guo, Bin -- Holder, Jimmy L Jr -- Rossner, Moritz J -- Nishino, Seiji -- Fu, Ying-Hui -- HL059596/HL/NHLBI NIH HHS/ -- MH074924/MH/NIMH NIH HHS/ -- R01 HL059596/HL/NHLBI NIH HHS/ -- R01 HL059596-09/HL/NHLBI NIH HHS/ -- New York, N.Y. -- Science. 2009 Aug 14;325(5942):866-70. doi: 10.1126/science.1174443.〈br /〉〈span class="detail_caption"〉Author address: 〈/span〉Department of Neurology, University of California at San Francisco, Mission Bay, 1550 Fourth Street, San Francisco, CA 94158, USA.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/19679812" target="_blank"〉PubMed〈/a〉
    Keywords: Activity Cycles/genetics ; Adolescent ; Adult ; Aged ; Amino Acid Sequence ; Amino Acid Substitution ; Animals ; Animals, Genetically Modified ; Basic Helix-Loop-Helix Transcription Factors/chemistry/*genetics/physiology ; Child ; Circadian Rhythm/genetics ; Drosophila/genetics ; Electroencephalography ; Electromyography ; Female ; Homeostasis ; Humans ; Male ; Mice ; Mice, Knockout ; Mice, Transgenic ; Middle Aged ; Molecular Sequence Data ; Pedigree ; Point Mutation ; Sleep/*genetics/physiology ; Sleep Deprivation ; Sleep, REM/genetics/physiology ; Transcription Factors/chemistry/genetics/physiology ; Wakefulness
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    American Association for the Advancement of Science (AAAS)
    Publication Date: 2009-02-14
    Description: 〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉McCarthy, James J -- New York, N.Y. -- Science. 2009 Feb 13;323(5916):853. doi: 10.1126/science.1171006.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/19213881" target="_blank"〉PubMed〈/a〉
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    American Association for the Advancement of Science (AAAS)
    Publication Date: 2009-12-19
    Description: 〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Alberts, Bruce -- New York, N.Y. -- Science. 2009 Dec 18;326(5960):1589. doi: 10.1126/science.1185821.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/20019250" target="_blank"〉PubMed〈/a〉
    Keywords: Animals ; Astronomical Phenomena ; Fossils ; Gamma Rays ; *Hominidae ; *Science
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  • 34
    Publication Date: 2009-08-29
    Description: 〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉McCaw, James M -- McVernon, Jodie -- McBryde, Emma S -- Mathews, John D -- New York, N.Y. -- Science. 2009 Aug 28;325(5944):1071; author reply 1072-3. doi: 10.1126/science.325_1071a.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/19713508" target="_blank"〉PubMed〈/a〉
    Keywords: Adult ; Child ; Disease Susceptibility ; Humans ; Immunity ; *Influenza A Virus, H1N1 Subtype/immunology ; Influenza, Human/*epidemiology/*immunology
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    American Association for the Advancement of Science (AAAS)
    Publication Date: 2009-08-15
    Description: 〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Service, Robert F -- New York, N.Y. -- Science. 2009 Aug 14;325(5942):809. doi: 10.1126/science.325_809.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/19679787" target="_blank"〉PubMed〈/a〉
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    American Association for the Advancement of Science (AAAS)
    Publication Date: 2009-07-25
    Description: 〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Vukusic, Pete -- BB/E000177/1/Biotechnology and Biological Sciences Research Council/United Kingdom -- JF16983/Biotechnology and Biological Sciences Research Council/United Kingdom -- New York, N.Y. -- Science. 2009 Jul 24;325(5939):398-9. doi: 10.1126/science.1177729.〈br /〉〈span class="detail_caption"〉Author address: 〈/span〉School of Physics, University of Exeter, Exeter EX4 4QL, UK. p.vukusic@ex.ac.uk〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/19628844" target="_blank"〉PubMed〈/a〉
    Keywords: Animal Communication ; Animals ; Beetles/anatomy & histology/*physiology ; Color ; Nanostructures ; Radiation
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    American Association for the Advancement of Science (AAAS)
    Publication Date: 2009-07-25
    Description: 〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Kleppner, Daniel -- Sharp, Phillip A -- New York, N.Y. -- Science. 2009 Jul 24;325(5939):368. doi: 10.1126/science.1178927.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/19628822" target="_blank"〉PubMed〈/a〉
    Keywords: *Automatic Data Processing/standards/trends ; *Research/standards/trends
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    American Association for the Advancement of Science (AAAS)
    Publication Date: 2009-08-08
    Description: 〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Service, Robert F -- New York, N.Y. -- Science. 2009 Aug 7;325(5941):692-3. doi: 10.1126/science.325_692.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/19661413" target="_blank"〉PubMed〈/a〉
    Keywords: Chemical Industry/*legislation & jurisprudence ; *Government Regulation ; *Hazardous Substances ; Humans ; Legislation as Topic ; Toxicity Tests ; United States ; United States Environmental Protection Agency/*legislation & jurisprudence
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  • 39
    Publication Date: 2009-05-02
    Description: Mercury is surrounded by a tenuous exosphere that is supplied primarily by the planet's surface materials and is known to contain sodium, potassium, and calcium. Observations by the Mercury Atmospheric and Surface Composition Spectrometer during MESSENGER's second Mercury flyby revealed the presence of neutral magnesium in the tail (anti-sunward) region of the exosphere, as well as differing spatial distributions of magnesium, calcium, and sodium atoms in both the tail and the nightside, near-planet exosphere. Analysis of these observations, supplemented by observations during the first Mercury flyby, as well as those by other MESSENGER instruments, suggests that the distinct spatial distributions arise from a combination of differences in source, transfer, and loss processes.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉McClintock, William E -- Vervack, Ronald J Jr -- Bradley, E Todd -- Killen, Rosemary M -- Mouawad, Nelly -- Sprague, Ann L -- Burger, Matthew H -- Solomon, Sean C -- Izenberg, Noam R -- New York, N.Y. -- Science. 2009 May 1;324(5927):610-3. doi: 10.1126/science.1172525.〈br /〉〈span class="detail_caption"〉Author address: 〈/span〉Laboratory for Atmospheric and Space Physics, University of Colorado, Boulder, CO 80303, USA. william.mcclintock@colorado.edu〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/19407195" target="_blank"〉PubMed〈/a〉
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  • 40
    Publication Date: 2009-12-08
    Description: 〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Duffy, J Emmett -- Canuel, Elizabeth A -- Adey, Walter -- Swaddle, John P -- New York, N.Y. -- Science. 2009 Dec 4;326(5958):1345; author reply 1346. doi: 10.1126/science.326.5958.1345-a.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/19965739" target="_blank"〉PubMed〈/a〉
    Keywords: *Biofuels ; *Eukaryota
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  • 41
    Publication Date: 2009-07-04
    Description: The Wet Chemistry Laboratory on the Phoenix Mars Lander performed aqueous chemical analyses of martian soil from the polygon-patterned northern plains of the Vastitas Borealis. The solutions contained approximately 10 mM of dissolved salts with 0.4 to 0.6% perchlorate (ClO4) by mass leached from each sample. The remaining anions included small concentrations of chloride, bicarbonate, and possibly sulfate. Cations were dominated by Mg2+ and Na+, with small contributions from K+ and Ca2+. A moderately alkaline pH of 7.7 +/- 0.5 was measured, consistent with a carbonate-buffered solution. Samples analyzed from the surface and the excavated boundary of the approximately 5-centimeter-deep ice table showed no significant difference in soluble chemistry.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Hecht, M H -- Kounaves, S P -- Quinn, R C -- West, S J -- Young, S M M -- Ming, D W -- Catling, D C -- Clark, B C -- Boynton, W V -- Hoffman, J -- Deflores, L P -- Gospodinova, K -- Kapit, J -- Smith, P H -- New York, N.Y. -- Science. 2009 Jul 3;325(5936):64-7. doi: 10.1126/science.1172466.〈br /〉〈span class="detail_caption"〉Author address: 〈/span〉Jet Propulsion Laboratory, California Institute of Technology, Pasadena, CA 91109, USA. michael.h.hecht@jpl.nasa.gov〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/19574385" target="_blank"〉PubMed〈/a〉
    Keywords: *Anions ; *Cations ; Chemical Phenomena ; Extraterrestrial Environment ; Hydrogen-Ion Concentration ; *Mars ; Oxidation-Reduction ; *Perchlorates ; Solubility ; Spacecraft ; Temperature ; Water
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    American Association for the Advancement of Science (AAAS)
    Publication Date: 2009-12-08
    Description: 〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Alberts, Bruce -- New York, N.Y. -- Science. 2009 Nov 13;326(5955):916. doi: 10.1126/science.1184202.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/19965482" target="_blank"〉PubMed〈/a〉
    Keywords: *Education, Graduate ; Humans ; *Mentors ; *Research/education ; Research Personnel/*education ; Science/*education
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  • 43
    Publication Date: 2009-07-18
    Description: Retrotransposition of processed mRNAs is a common source of novel sequence acquired during the evolution of genomes. Although the vast majority of retroposed gene copies, or retrogenes, rapidly accumulate debilitating mutations that disrupt the reading frame, a small percentage become new genes that encode functional proteins. By using a multibreed association analysis in the domestic dog, we demonstrate that expression of a recently acquired retrogene encoding fibroblast growth factor 4 (fgf4) is strongly associated with chondrodysplasia, a short-legged phenotype that defines at least 19 dog breeds including dachshund, corgi, and basset hound. These results illustrate the important role of a single evolutionary event in constraining and directing phenotypic diversity in the domestic dog.〈br /〉〈br /〉〈a href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2748762/" target="_blank"〉〈img src="https://static.pubmed.gov/portal/portal3rc.fcgi/4089621/img/3977009" border="0"〉〈/a〉   〈a href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2748762/" target="_blank"〉This paper as free author manuscript - peer-reviewed and accepted for publication〈/a〉〈br /〉〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Parker, Heidi G -- VonHoldt, Bridgett M -- Quignon, Pascale -- Margulies, Elliott H -- Shao, Stephanie -- Mosher, Dana S -- Spady, Tyrone C -- Elkahloun, Abdel -- Cargill, Michele -- Jones, Paul G -- Maslen, Cheryl L -- Acland, Gregory M -- Sutter, Nathan B -- Kuroki, Keiichi -- Bustamante, Carlos D -- Wayne, Robert K -- Ostrander, Elaine A -- 1R01GM83606/GM/NIGMS NIH HHS/ -- 1R24GM082910/GM/NIGMS NIH HHS/ -- 5R01EY006855/EY/NEI NIH HHS/ -- R01 EY006855/EY/NEI NIH HHS/ -- R01 EY006855-25/EY/NEI NIH HHS/ -- Z99 HG999999/Intramural NIH HHS/ -- New York, N.Y. -- Science. 2009 Aug 21;325(5943):995-8. doi: 10.1126/science.1173275. Epub 2009 Jul 16.〈br /〉〈span class="detail_caption"〉Author address: 〈/span〉Cancer Genetics Branch, National Human Genome Research Institute, National Institutes of Health, Bethesda, MD 20892, USA.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/19608863" target="_blank"〉PubMed〈/a〉
    Keywords: Animals ; Breeding ; Chondrocytes/metabolism ; Dogs/anatomy & histology/*genetics ; Evolution, Molecular ; Extremities/*anatomy & histology ; Fibroblast Growth Factor 4/*genetics ; *Gene Duplication ; *Gene Expression Regulation ; Gene Frequency ; Genes, Duplicate ; Genome-Wide Association Study ; Haplotypes ; Humerus/metabolism ; Long Interspersed Nucleotide Elements ; Oligonucleotide Array Sequence Analysis ; Pedigree ; Phenotype ; Polymorphism, Single Nucleotide ; Regulatory Sequences, Nucleic Acid ; Retroelements/*genetics ; Selection, Genetic
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    American Association for the Advancement of Science (AAAS)
    Publication Date: 2009-03-17
    Description: 〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉McClung, C Robertson -- New York, N.Y. -- Science. 2009 Mar 13;323(5920):1440-1. doi: 10.1126/science.1171418.〈br /〉〈span class="detail_caption"〉Author address: 〈/span〉Department of Biological Sciences, Dartmouth College, Hanover, NH 03755, USA. c.robertson.mcclung@dartmouth.edu〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/19286545" target="_blank"〉PubMed〈/a〉
    Keywords: Arabidopsis/genetics/*physiology ; Arabidopsis Proteins/genetics/*metabolism ; Biological Clocks/*genetics ; Circadian Rhythm/*genetics ; DNA-Binding Proteins/genetics/metabolism ; Feedback, Physiological ; *Gene Expression Regulation, Plant ; Genes, Plant ; Promoter Regions, Genetic ; Repressor Proteins/genetics/*metabolism ; Transcription Factors/genetics/*metabolism ; Transcription, Genetic
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    American Association for the Advancement of Science (AAAS)
    Publication Date: 2009-03-21
    Description: 〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Parren, Paul W H I -- Burton, Dennis R -- New York, N.Y. -- Science. 2009 Mar 20;323(5921):1567-8. doi: 10.1126/science.1172253.〈br /〉〈span class="detail_caption"〉Author address: 〈/span〉Genmab, Yalelaan 60, 3584 CM Utrecht, Netherlands. p.parren@genmab.com〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/19299606" target="_blank"〉PubMed〈/a〉
    Keywords: Animals ; Antibodies, Bispecific/chemistry/*immunology/therapeutic use ; Antibodies, Monoclonal/chemistry/genetics/*immunology/therapeutic use ; Antibodies, Monoclonal, Humanized ; Antibody Affinity ; Antibody Specificity ; Binding Sites, Antibody ; Crystallography, X-Ray ; Epitopes ; Genetic Engineering ; Humans ; Neoplasms, Experimental/drug therapy ; Receptor, ErbB-2/*immunology ; Trastuzumab ; Vascular Endothelial Growth Factor A/*immunology
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    American Association for the Advancement of Science (AAAS)
    Publication Date: 2009-12-08
    Description: 〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Alberts, Bruce -- New York, N.Y. -- Science. 2009 Nov 27;326(5957):1163. doi: 10.1126/science.1184848.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/19965437" target="_blank"〉PubMed〈/a〉
    Keywords: *Biomedical Research/economics ; Budgets ; Financing, Government ; *Motivation ; National Institutes of Health (U.S.)/*economics ; *Peer Review, Research ; *Research Support as Topic ; United States
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  • 47
    Publication Date: 2009-03-17
    Description: The three-dimensional molecular structure of DNA, specifically the shape of the backbone and grooves of genomic DNA, can be dramatically affected by nucleotide changes, which can cause differences in protein-binding affinity and phenotype. We developed an algorithm to measure constraint on the basis of similarity of DNA topography among multiple species, using hydroxyl radical cleavage patterns to interrogate the solvent-accessible surface area of DNA. This algorithm found that 12% of bases in the human genome are evolutionarily constrained-double the number detected by nucleotide sequence-based algorithms. Topography-informed constrained regions correlated with functional noncoding elements, including enhancers, better than did regions identified solely on the basis of nucleotide sequence. These results support the idea that the molecular shape of DNA is under selection and can identify evolutionary history.〈br /〉〈br /〉〈a href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2749491/" target="_blank"〉〈img src="https://static.pubmed.gov/portal/portal3rc.fcgi/4089621/img/3977009" border="0"〉〈/a〉   〈a href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2749491/" target="_blank"〉This paper as free author manuscript - peer-reviewed and accepted for publication〈/a〉〈br /〉〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Parker, Stephen C J -- Hansen, Loren -- Abaan, Hatice Ozel -- Tullius, Thomas D -- Margulies, Elliott H -- R01 HG003541/HG/NHGRI NIH HHS/ -- R01 HG003541-03/HG/NHGRI NIH HHS/ -- Intramural NIH HHS/ -- New York, N.Y. -- Science. 2009 Apr 17;324(5925):389-92. doi: 10.1126/science.1169050. Epub 2009 Mar 12.〈br /〉〈span class="detail_caption"〉Author address: 〈/span〉Bioinformatics Program, Boston University, Boston, MA 02215, USA.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/19286520" target="_blank"〉PubMed〈/a〉
    Keywords: Algorithms ; Amino Acid Motifs ; Base Sequence ; Binding Sites ; Conserved Sequence ; DNA/*chemistry/genetics ; Deoxyribonuclease I/metabolism ; Early Growth Response Protein 1/genetics/metabolism ; Evolution, Molecular ; *Genome, Human ; Humans ; Mutant Proteins/metabolism ; Nucleic Acid Conformation ; Phenotype ; Polymorphism, Single Nucleotide ; Selection, Genetic
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  • 48
    Publication Date: 2009-02-07
    Description: The glass transition is the freezing of a liquid into a solid state without evident structural order. Although glassy materials are well characterized experimentally, the existence of a phase transition into the glass state remains controversial. Here, we present numerical evidence for the existence of a novel first-order dynamical phase transition in atomistic models of structural glass formers. In contrast to equilibrium phase transitions, which occur in configuration space, this transition occurs in trajectory space, and it is controlled by variables that drive the system out of equilibrium. Coexistence is established between an ergodic phase with finite relaxation time and a nonergodic phase of immobile molecular configurations. Thus, we connect the glass transition to a true phase transition, offering the possibility of a unified picture of glassy phenomena.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Hedges, Lester O -- Jack, Robert L -- Garrahan, Juan P -- Chandler, David -- New York, N.Y. -- Science. 2009 Mar 6;323(5919):1309-13. doi: 10.1126/science.1166665. Epub 2009 Feb 5.〈br /〉〈span class="detail_caption"〉Author address: 〈/span〉Department of Chemistry, University of California, Berkeley, CA 94720-1460, USA.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/19197025" target="_blank"〉PubMed〈/a〉
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    American Association for the Advancement of Science (AAAS)
    Publication Date: 2009-09-05
    Description: 〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Duncan, Martin -- New York, N.Y. -- Science. 2009 Sep 4;325(5945):1211-2. doi: 10.1126/science.1177312.〈br /〉〈span class="detail_caption"〉Author address: 〈/span〉Department of Physics, Engineering Physics and Astronomy, Queen's University, Kingston, Ontario, K7L 3N6, Canada. duncan@astro.queensu.ca〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/19729643" target="_blank"〉PubMed〈/a〉
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    American Association for the Advancement of Science (AAAS)
    Publication Date: 2009-09-26
    Description: 〈br /〉〈br /〉〈a href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2847887/" target="_blank"〉〈img src="https://static.pubmed.gov/portal/portal3rc.fcgi/4089621/img/3977009" border="0"〉〈/a〉   〈a href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2847887/" target="_blank"〉This paper as free author manuscript - peer-reviewed and accepted for publication〈/a〉〈br /〉〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Hedrick, Stephen M -- R01 AI021372/AI/NIAID NIH HHS/ -- R01 AI021372-26/AI/NIAID NIH HHS/ -- New York, N.Y. -- Science. 2009 Sep 25;325(5948):1623-4. doi: 10.1126/science.325_1623a.〈br /〉〈span class="detail_caption"〉Author address: 〈/span〉Department of Biological Sciences, University of California, San Diego, La Jolla, CA 92093-0377, USA. shedrick@ucsd.edu〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/19779174" target="_blank"〉PubMed〈/a〉
    Keywords: Animals ; *Biological Evolution ; Immune System/*physiology ; *Immunity ; Immunity, Innate ; Invertebrates/*immunology ; Selection, Genetic ; Vertebrates/*immunology
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    American Association for the Advancement of Science (AAAS)
    Publication Date: 2009-08-15
    Description: 〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Call, Josep -- Carpenter, Malinda -- New York, N.Y. -- Science. 2009 Aug 14;325(5942):824-5. doi: 10.1126/science.1178714.〈br /〉〈span class="detail_caption"〉Author address: 〈/span〉Max Planck Institute for Evolutionary Anthropology, Deutscher Platz 6, D-04103 Leipzig, Germany. call@eva.mpg.de〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/19679802" target="_blank"〉PubMed〈/a〉
    Keywords: Animals ; Cebus/*psychology ; Humans ; *Imitative Behavior ; *Social Behavior
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    American Association for the Advancement of Science (AAAS)
    Publication Date: 2009-06-06
    Description: 〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Service, Robert F -- New York, N.Y. -- Science. 2009 Jun 5;324(5932):1257-9. doi: 10.1126/science.324_1257.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/19498144" target="_blank"〉PubMed〈/a〉
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    American Association for the Advancement of Science (AAAS)
    Publication Date: 2009-05-16
    Description: 〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Service, Robert F -- New York, N.Y. -- Science. 2009 May 15;324(5929):876. doi: 10.1126/science.324_876.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/19443762" target="_blank"〉PubMed〈/a〉
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    American Association for the Advancement of Science (AAAS)
    Publication Date: 2009-05-23
    Description: 〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Wade, Nicholas -- New York, N.Y. -- Science. 2009 May 22;324(5930):1028. doi: 10.1126/science.1175760.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/19460997" target="_blank"〉PubMed〈/a〉
    Keywords: Great Britain ; History, 20th Century ; History, 21st Century ; Periodicals as Topic/*history ; Publishing/*history/organization & administration ; Science
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  • 55
    Publication Date: 2009-10-17
    Description: The Sun moves through the local interstellar medium, continuously emitting ionized, supersonic solar wind plasma and carving out a cavity in interstellar space called the heliosphere. The recently launched Interstellar Boundary Explorer (IBEX) spacecraft has completed its first all-sky maps of the interstellar interaction at the edge of the heliosphere by imaging energetic neutral atoms (ENAs) emanating from this region. We found a bright ribbon of ENA emission, unpredicted by prior models or theories, that may be ordered by the local interstellar magnetic field interacting with the heliosphere. This ribbon is superposed on globally distributed flux variations ordered by both the solar wind structure and the direction of motion through the interstellar medium. Our results indicate that the external galactic environment strongly imprints the heliosphere.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉McComas, D J -- Allegrini, F -- Bochsler, P -- Bzowski, M -- Christian, E R -- Crew, G B -- DeMajistre, R -- Fahr, H -- Fichtner, H -- Frisch, P C -- Funsten, H O -- Fuselier, S A -- Gloeckler, G -- Gruntman, M -- Heerikhuisen, J -- Izmodenov, V -- Janzen, P -- Knappenberger, P -- Krimigis, S -- Kucharek, H -- Lee, M -- Livadiotis, G -- Livi, S -- MacDowall, R J -- Mitchell, D -- Mobius, E -- Moore, T -- Pogorelov, N V -- Reisenfeld, D -- Roelof, E -- Saul, L -- Schwadron, N A -- Valek, P W -- Vanderspek, R -- Wurz, P -- Zank, G P -- New York, N.Y. -- Science. 2009 Nov 13;326(5955):959-62. doi: 10.1126/science.1180906. Epub 2009 Oct 15.〈br /〉〈span class="detail_caption"〉Author address: 〈/span〉Southwest Research Institute, San Antonio, TX 78228, USA. dmccomas@swri.org〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/19833923" target="_blank"〉PubMed〈/a〉
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    American Association for the Advancement of Science (AAAS)
    Publication Date: 2009-03-17
    Description: 〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Wald, Chelsea -- New York, N.Y. -- Science. 2009 Mar 13;323(5920):1418. doi: 10.1126/science.323.5920.1418.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/19286529" target="_blank"〉PubMed〈/a〉
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    Publication Date: 2009-02-07
    Description: Prabhakar et al. (Reports, 5 September 2008, p. 1346) argued that the conserved noncoding sequence HACNS1 has undergone positive selection and contributed to human adaptation. However, the pattern of substitution in HACNS1 is more consistent with the neutral process of biased gene conversion (BGC). The reported human-specific gain of function is likely due to the accumulation of deleterious mutations driven by BGC, not positive selection.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Duret, Laurent -- Galtier, Nicolas -- New York, N.Y. -- Science. 2009 Feb 6;323(5915):714; author reply 714. doi: 10.1126/science.1165848.〈br /〉〈span class="detail_caption"〉Author address: 〈/span〉Universite de Lyon, Universite Lyon 1, CNRS, UMR5558, Laboratoire de Biometrie et Biologie Evolutive, F-69622, Villeurbanne, France. duret@biomserv.univ-lyon1.fr〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/19197042" target="_blank"〉PubMed〈/a〉
    Keywords: Animals ; *Conserved Sequence ; *Enhancer Elements, Genetic ; Evolution, Molecular ; *Gene Conversion ; Humans ; Mutation ; Recombination, Genetic ; Selection, Genetic
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    Publication Date: 2009-11-11
    Description: 〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Parrish, David D -- Zhu, Tong -- New York, N.Y. -- Science. 2009 Oct 30;326(5953):674-5. doi: 10.1126/science.1176064.〈br /〉〈span class="detail_caption"〉Author address: 〈/span〉Chemical Sciences Division, Earth System Research Laboratory, National Oceanic and Atmospheric Administration, Boulder, CO 80305, USA. david.d.parrish@noaa.gov〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/19900921" target="_blank"〉PubMed〈/a〉
    Keywords: *Air Pollution/adverse effects ; *Cities ; *Climate Change ; Humans ; Particulate Matter ; Population Density
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    American Association for the Advancement of Science (AAAS)
    Publication Date: 2009-04-11
    Description: 〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Klopfer, Peter H -- New York, N.Y. -- Science. 2009 Apr 10;324(5924):177. doi: 10.1126/science.324.5924.177b.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/19359566" target="_blank"〉PubMed〈/a〉
    Keywords: Cannabis ; Poaceae ; Security Measures ; Seeds ; Travel ; *Wit and Humor as Topic
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    American Association for the Advancement of Science (AAAS)
    Publication Date: 2009-10-10
    Description: 〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Alberts, Bruce -- New York, N.Y. -- Science. 2009 Oct 9;326(5950):205. doi: 10.1126/science.1182658.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/19815740" target="_blank"〉PubMed〈/a〉
    Keywords: *Biomedical Research ; *Clinical Medicine ; Diffusion of Innovation ; Humans ; *Interdisciplinary Communication ; *Periodicals as Topic
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    American Association for the Advancement of Science (AAAS)
    Publication Date: 2009-12-19
    Description: 〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Service, Robert F -- New York, N.Y. -- Science. 2009 Dec 18;326(5960):1610-1. doi: 10.1126/science.326.5960.1610.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/20019260" target="_blank"〉PubMed〈/a〉
    Keywords: Amino Acids/chemistry/*metabolism ; Crime ; Glycoproteins/chemistry/metabolism ; Glycosylation ; Proteins/chemistry/*metabolism ; Research/*standards ; *Retraction of Publication as Topic
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    American Association for the Advancement of Science (AAAS)
    Publication Date: 2009-04-11
    Description: 〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Vinson, Valda J -- New York, N.Y. -- Science. 2009 Apr 10;324(5924):197. doi: 10.1126/science.324.5924.197.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/19359575" target="_blank"〉PubMed〈/a〉
    Keywords: Evolution, Molecular ; Motion ; Protein Conformation ; Proteins/*chemistry/*physiology ; Signal Transduction ; Thermodynamics
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    American Association for the Advancement of Science (AAAS)
    Publication Date: 2009-05-09
    Description: Understanding of plant-pathogen coevolution in natural systems continues to develop as new theories at the population and species level are increasingly informed by studies unraveling the molecular basis of interactions between individual plants and their pathogens. The next challenge lies in further integration of these approaches to develop a comprehensive picture of how life history traits of both players interact with the environment to shape evolutionary trajectories.〈br /〉〈br /〉〈a href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2689373/" target="_blank"〉〈img src="https://static.pubmed.gov/portal/portal3rc.fcgi/4089621/img/3977009" border="0"〉〈/a〉   〈a href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2689373/" target="_blank"〉This paper as free author manuscript - peer-reviewed and accepted for publication〈/a〉〈br /〉〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Burdon, Jeremy J -- Thrall, Peter H -- R01 GM074265-01A2/GM/NIGMS NIH HHS/ -- New York, N.Y. -- Science. 2009 May 8;324(5928):755-6. doi: 10.1126/science.1171663.〈br /〉〈span class="detail_caption"〉Author address: 〈/span〉Commonwealth Scientific and Industrial Research Organization (CSIRO)-Plant Industry, Post Office Box 1600, Canberra, ACT 2601, Australia. Jeremy.Burdon@csiro.au〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/19423818" target="_blank"〉PubMed〈/a〉
    Keywords: *Biological Evolution ; *Ecosystem ; Fungal Proteins/genetics/metabolism ; Fungi/genetics/*pathogenicity/physiology ; *Host-Pathogen Interactions ; Immunity, Innate ; Plant Diseases/immunology/*microbiology ; Plant Proteins/genetics/metabolism ; Plants/genetics/immunology/metabolism/*microbiology
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    American Association for the Advancement of Science (AAAS)
    Publication Date: 2009-11-11
    Description: 〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Donazar, Jose A -- Margalida, Antoni -- Carrete, Martina -- Sanchez-Zapata, Jose A -- New York, N.Y. -- Science. 2009 Oct 30;326(5953):664. doi: 10.1126/science.326_664a.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/19900914" target="_blank"〉PubMed〈/a〉
    Keywords: Animals ; Birds/*physiology ; Conservation of Natural Resources ; Europe ; Food Supply ; Population Dynamics ; *Sanitation/legislation & jurisprudence
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    American Association for the Advancement of Science (AAAS)
    Publication Date: 2009-08-01
    Description: Microorganisms have critical roles in the functioning of soil in nutrient cycling, structural formation, and plant interactions, both positive and negative. These roles are important in reestablishing function and biodiversity in ecosystem restoration. Measurement of the community indicates the status of the system in relation to restoration targets and the effectiveness of management interventions, and manipulation of the community shows promise in the enhancement of the rate of recovery of degraded systems.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Harris, Jim -- New York, N.Y. -- Science. 2009 Jul 31;325(5940):573-4. doi: 10.1126/science.1172975.〈br /〉〈span class="detail_caption"〉Author address: 〈/span〉Department of Natural Resources, Cranfield University, Cranfield, Bedfordshire MK43 0AL, UK.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/19644111" target="_blank"〉PubMed〈/a〉
    Keywords: *Bacterial Physiological Phenomena ; Biodiversity ; *Conservation of Natural Resources ; *Ecosystem ; Fungi/*physiology ; Mycorrhizae/*physiology ; Plant Physiological Phenomena ; *Soil Microbiology ; Symbiosis
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  • 66
    Publication Date: 2009-09-26
    Description: Starburst galaxies exhibit in their central regions a highly increased rate of supernovae, the remnants of which are thought to accelerate energetic cosmic rays up to energies of approximately 10(15) electron volts. We report the detection of gamma rays--tracers of such cosmic rays--from the starburst galaxy NGC 253 using the High Energy Stereoscopic System (H.E.S.S.) array of imaging atmospheric Cherenkov telescopes. The gamma-ray flux above 220 billion electron volts is F = (5.5 +/- 1.0(stat) +/- 2.8(sys)) x 10(-13) cm(-2) s(-1), implying a cosmic-ray density about three orders of magnitude larger than that in the center of the Milky Way. The fraction of cosmic-ray energy channeled into gamma rays in this starburst environment is five times as large as that in our Galaxy.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Acero, F -- Aharonian, F -- Akhperjanian, A G -- Anton, G -- Barres de Almeida, U -- Bazer-Bachi, A R -- Becherini, Y -- Behera, B -- Bernlohr, K -- Bochow, A -- Boisson, C -- Bolmont, J -- Borrel, V -- Brucker, J -- Brun, F -- Brun, P -- Buhler, R -- Bulik, T -- Busching, I -- Boutelier, T -- Chadwick, P M -- Charbonnier, A -- Chaves, R C G -- Cheesebrough, A -- Chounet, L-M -- Clapson, A C -- Coignet, G -- Dalton, M -- Daniel, M K -- Davids, I D -- Degrange, B -- Deil, C -- Dickinson, H J -- Djannati-Atai, A -- Domainko, W -- Drury, L O'C -- Dubois, F -- Dubus, G -- Dyks, J -- Dyrda, M -- Egberts, K -- Emmanoulopoulos, D -- Espigat, P -- Farnier, C -- Fegan, S -- Feinstein, F -- Fiasson, A -- Forster, A -- Fontaine, G -- Fussling, M -- Gabici, S -- Gallant, Y A -- Gerard, L -- Gerbig, D -- Giebels, B -- Glicenstein, J F -- Gluck, B -- Goret, P -- Goring, D -- Hauser, D -- Hauser, M -- Heinz, S -- Heinzelmann, G -- Henri, G -- Hermann, G -- Hinton, J A -- Hoffmann, A -- Hofmann, W -- Hofverberg, P -- Hoppe, S -- Horns, D -- Jacholkowska, A -- de Jager, O C -- Jahn, C -- Jung, I -- Katarzynski, K -- Katz, U -- Kaufmann, S -- Kerschhaggl, M -- Khangulyan, D -- Khelifi, B -- Keogh, D -- Klochkov, D -- Kluzniak, W -- Kneiske, T -- Komin, Nu -- Kosack, K -- Kossakowski, R -- Lamanna, G -- Lenain, J-P -- Lohse, T -- Marandon, V -- Martineau-Huynh, O -- Marcowith, A -- Masbou, J -- Maurin, D -- McComb, T J L -- Medina, M C -- Mehault, J -- Moderski, R -- Moulin, E -- Naumann-Godo, M -- de Naurois, M -- Nedbal, D -- Nekrassov, D -- Nicholas, B -- Niemiec, J -- Nolan, S J -- Ohm, S -- Olive, J-F -- de Ona Wilhelmi, E -- Orford, K J -- Ostrowski, M -- Panter, M -- Paz Arribas, M -- Pedaletti, G -- Pelletier, G -- Petrucci, P-O -- Pita, S -- Puhlhofer, G -- Punch, M -- Quirrenbach, A -- Raubenheimer, B C -- Raue, M -- Rayner, S M -- Reimer, O -- Renaud, M -- Rieger, F -- Ripken, J -- Rob, L -- Rosier-Lees, S -- Rowell, G -- Rudak, B -- Rulten, C B -- Ruppel, J -- Sahakian, V -- Santangelo, A -- Schlickeiser, R -- Schock, F M -- Schwanke, U -- Schwarzburg, S -- Schwemmer, S -- Shalchi, A -- Sikora, M -- Skilton, J L -- Sol, H -- Stawarz, L -- Steenkamp, R -- Stegmann, C -- Stinzing, F -- Superina, G -- Szostek, A -- Tam, P H -- Tavernet, J-P -- Terrier, R -- Tibolla, O -- Tluczykont, M -- van Eldik, C -- Vasileiadis, G -- Venter, C -- Venter, L -- Vialle, J P -- Vincent, P -- Vivier, M -- Volk, H J -- Volpe, F -- Wagner, S J -- Ward, M -- Zdziarski, A A -- Zech, A -- New York, N.Y. -- Science. 2009 Nov 20;326(5956):1080-2. doi: 10.1126/science.1178826. Epub 2009 Sep 24.〈br /〉〈span class="detail_caption"〉Author address: 〈/span〉Laboratoire de Physique Theorique et Astroparticules, Universite Montpellier 2, CNRS/IN2P3, CC 70, Place Eugene Bataillon, F-34095 Montpellier Cedex 5, France.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/19779150" target="_blank"〉PubMed〈/a〉
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    American Association for the Advancement of Science (AAAS)
    Publication Date: 2009-03-28
    Description: 〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Kintisch, Eli -- New York, N.Y. -- Science. 2009 Mar 27;323(5922):1656. doi: 10.1126/science.323.5922.1656a.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/19325084" target="_blank"〉PubMed〈/a〉
    Keywords: *Politics ; United States ; United States Government Agencies/*organization & administration
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  • 68
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    American Association for the Advancement of Science (AAAS)
    Publication Date: 2009-02-07
    Description: 〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉May, Robert M -- Harvey, Paul H -- New York, N.Y. -- Science. 2009 Feb 6;323(5915):687. doi: 10.1126/science.1170937.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/19197026" target="_blank"〉PubMed〈/a〉
    Keywords: Animals ; *Biodiversity ; *Classification ; Ecosystem ; Extinction, Biological ; *Genetic Speciation ; Plants/classification
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  • 69
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    American Association for the Advancement of Science (AAAS)
    Publication Date: 2009-08-01
    Description: Ecological restoration is an activity that ideally results in the return of an ecosystem to an undisturbed state. Ecosystem services are the benefits humans derive from ecosystems. The two have been joined to support growing environmental markets with the goal of creating restoration-based credits that can be bought and sold. However, the allure of these markets may be overshadowing shortcomings in the science and practice of ecological restoration. Before making risky investments, we must understand why and when restoration efforts fall short of recovering the full suite of ecosystem services, what can be done to improve restoration success, and why direct measurement of the biophysical processes that support ecosystem services is the only way to guarantee the future success of these markets. Without new science and an oversight framework to protect the ecosystem service assets which people depend, markets could actually accelerate environmental degradation.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Palmer, Margaret A -- Filoso, Solange -- New York, N.Y. -- Science. 2009 Jul 31;325(5940):575-6. doi: 10.1126/science.1172976.〈br /〉〈span class="detail_caption"〉Author address: 〈/span〉Chesapeake Biological Laboratory, University of Maryland Center for Environmental Science, Solomons, MD 20688, USA. mpalmer@umd.edu〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/19644112" target="_blank"〉PubMed〈/a〉
    Keywords: Biodiversity ; Biophysical Processes ; *Conservation of Natural Resources ; *Ecosystem ; *Environment ; Humans ; Wetlands
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    American Association for the Advancement of Science (AAAS)
    Publication Date: 2009-12-17
    Description: 〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Service, Robert F -- New York, N.Y. -- Science. 2009 Dec 11;326(5959):1474. doi: 10.1126/science.326.5959.1474.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/20007879" target="_blank"〉PubMed〈/a〉
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  • 71
    Publication Date: 2009-06-23
    Description: 〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Vitousek, P M -- Naylor, R -- Crews, T -- David, M B -- Drinkwater, L E -- Holland, E -- Johnes, P J -- Katzenberger, J -- Martinelli, L A -- Matson, P A -- Nziguheba, G -- Ojima, D -- Palm, C A -- Robertson, G P -- Sanchez, P A -- Townsend, A R -- Zhang, F S -- New York, N.Y. -- Science. 2009 Jun 19;324(5934):1519-20. doi: 10.1126/science.1170261.〈br /〉〈span class="detail_caption"〉Author address: 〈/span〉Department of Biology, Stanford University, Stanford, CA 94305, USA. vitousek@stanford.edu〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/19541981" target="_blank"〉PubMed〈/a〉
    Keywords: *Agriculture/methods ; China ; Environmental Pollution ; Fertilizers ; Kenya ; Nitrogen ; Phosphorus ; *Soil ; United States ; *Zea mays/growth & development
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    American Association for the Advancement of Science (AAAS)
    Publication Date: 2009-03-28
    Description: 〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Service, Robert F -- New York, N.Y. -- Science. 2009 Mar 27;323(5922):1665. doi: 10.1126/science.323.5922.1665.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/19325095" target="_blank"〉PubMed〈/a〉
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  • 73
    Publication Date: 2009-05-09
    Description: The quantity of land available to grow biofuel crops without affecting food prices or greenhouse gas (GHG) emissions from land conversion is limited. Therefore, bioenergy should maximize land-use efficiency when addressing transportation and climate change goals. Biomass could power either internal combustion or electric vehicles, but the relative land-use efficiency of these two energy pathways is not well quantified. Here, we show that bioelectricity outperforms ethanol across a range of feedstocks, conversion technologies, and vehicle classes. Bioelectricity produces an average of 81% more transportation kilometers and 108% more emissions offsets per unit area of cropland than does cellulosic ethanol. These results suggest that alternative bioenergy pathways have large differences in how efficiently they use the available land to achieve transportation and climate goals.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Campbell, J E -- Lobell, D B -- Field, C B -- New York, N.Y. -- Science. 2009 May 22;324(5930):1055-7. doi: 10.1126/science.1168885. Epub 2009 May 7.〈br /〉〈span class="detail_caption"〉Author address: 〈/span〉College of Engineering, University of California, Merced, CA 95344, USA. ecampbell3@ucmerced.edu〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/19423776" target="_blank"〉PubMed〈/a〉
    Keywords: Agriculture ; Air Pollutants ; Automobile Driving ; *Bioelectric Energy Sources ; *Biomass ; *Energy-Generating Resources ; *Ethanol ; Greenhouse Effect ; *Motor Vehicles ; Zea mays
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  • 74
    Publication Date: 2009-02-21
    Description: Thin layers of phytoplankton are important hotspots of ecological activity that are found in the coastal ocean, meters beneath the surface, and contain cell concentrations up to two orders of magnitude above ambient concentrations. Current interpretations of their formation favor abiotic processes, yet many phytoplankton species found in these layers are motile. We demonstrated that layers formed when the vertical migration of phytoplankton was disrupted by hydrodynamic shear. This mechanism, which we call gyrotactic trapping, can be responsible for the thin layers of phytoplankton commonly observed in the ocean. These results reveal that the coupling between active microorganism motility and ambient fluid motion can shape the macroscopic features of the marine ecological landscape.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Durham, William M -- Kessler, John O -- Stocker, Roman -- New York, N.Y. -- Science. 2009 Feb 20;323(5917):1067-70. doi: 10.1126/science.1167334.〈br /〉〈span class="detail_caption"〉Author address: 〈/span〉Department of Civil and Environmental Engineering, Massachusetts Institute of Technology (MIT), Cambridge, MA 02139, USA.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/19229037" target="_blank"〉PubMed〈/a〉
    Keywords: Animals ; Biomechanical Phenomena ; Cell Shape ; Chlamydomonas/cytology/*physiology ; *Ecosystem ; Flagella ; Gravitation ; Movement ; Phytoplankton/cytology/*physiology ; *Water ; *Water Movements
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    American Association for the Advancement of Science (AAAS)
    Publication Date: 2009-07-18
    Description: 〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Alberts, Bruce -- New York, N.Y. -- Science. 2009 Jul 17;325(5938):266. doi: 10.1126/science.325_266d.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/19608895" target="_blank"〉PubMed〈/a〉
    Keywords: *Access to Information ; *Editorial Policies ; *Internet ; *Science
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  • 76
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    American Association for the Advancement of Science (AAAS)
    Publication Date: 2009-03-17
    Description: Networks in which the formation of connections is governed by a random process often undergo a percolation transition, wherein around a critical point, the addition of a small number of connections causes a sizable fraction of the network to suddenly become linked together. Typically such transitions are continuous, so that the percentage of the network linked together tends to zero right above the transition point. Whether percolation transitions could be discontinuous has been an open question. Here, we show that incorporating a limited amount of choice in the classic Erdos-Renyi network formation model causes its percolation transition to become discontinuous.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Achlioptas, Dimitris -- D'Souza, Raissa M -- Spencer, Joel -- New York, N.Y. -- Science. 2009 Mar 13;323(5920):1453-5. doi: 10.1126/science.1167782.〈br /〉〈span class="detail_caption"〉Author address: 〈/span〉Department of Computer Science, University of California at Santa Cruz, Santa Cruz, CA 95064, USA.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/19286548" target="_blank"〉PubMed〈/a〉
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  • 77
    Publication Date: 2009-03-21
    Description: 〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Kintisch, Eli -- New York, N.Y. -- Science. 2009 Mar 20;323(5921):1546-7. doi: 10.1126/science.323.5921.1546.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/19299589" target="_blank"〉PubMed〈/a〉
    Keywords: Carbon ; Conservation of Natural Resources ; Ecosystem ; Energy-Generating Resources ; Forecasting ; *Greenhouse Effect ; Ice Cover
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  • 78
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    American Association for the Advancement of Science (AAAS)
    Publication Date: 2009-01-03
    Description: Online education is established, growing, and here to stay. It is creating new opportunities for students and also for faculty, regulators of education, and the educational institutions themselves. Much of what is being learned by the practitioners will flow into the large numbers of blended courses that will be developed and delivered on most campuses. Some of what is being learned will certainly improve pedagogical approaches and possibly affect other important problems, such as the lengthening time to completion of a degree. Online education is already providing better access to education for many, and many more will benefit from this increased access in the coming years.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Mayadas, A Frank -- Bourne, John -- Bacsich, Paul -- New York, N.Y. -- Science. 2009 Jan 2;323(5910):85-9. doi: 10.1126/science.1168874.〈br /〉〈span class="detail_caption"〉Author address: 〈/span〉Alfred P. Sloan Foundation, 630 Fifth Avenue, New York, NY 10111, USA. mayadas@sloan.org〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/19119225" target="_blank"〉PubMed〈/a〉
    Keywords: Computer-Assisted Instruction/economics ; *Education, Distance/economics ; Faculty ; Federal Government ; Humans ; *Internet ; Online Systems ; State Government ; Students ; Training Support ; United States ; *Universities
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  • 79
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    American Association for the Advancement of Science (AAAS)
    Publication Date: 2009-12-17
    Description: 〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Service, Robert F -- New York, N.Y. -- Science. 2009 Dec 11;326(5959):1472-5. doi: 10.1126/science.326.5959.1472.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/20007878" target="_blank"〉PubMed〈/a〉
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  • 80
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    American Association for the Advancement of Science (AAAS)
    Publication Date: 2009-07-25
    Description: 〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Eckstein, Eugene C -- New York, N.Y. -- Science. 2009 Jul 24;325(5939):392. doi: 10.1126/science.325_392a.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/19628840" target="_blank"〉PubMed〈/a〉
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  • 81
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    American Association for the Advancement of Science (AAAS)
    Publication Date: 2009-09-12
    Description: 〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Alberts, Bruce -- New York, N.Y. -- Science. 2009 Sep 11;325(5946):1319. doi: 10.1126/science.1181224.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/19745119" target="_blank"〉PubMed〈/a〉
    Keywords: Animals ; Antineoplastic Agents/pharmacology/therapeutic use ; *Biomedical Research ; DNA Repair ; Drug Discovery ; Humans ; Mutation ; *Neoplasms/drug therapy/genetics
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  • 82
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    American Association for the Advancement of Science (AAAS)
    Publication Date: 2009-03-03
    Description: 〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Heinrich, Andreas J -- New York, N.Y. -- Science. 2009 Feb 27;323(5918):1178-9. doi: 10.1126/science.1170744.〈br /〉〈span class="detail_caption"〉Author address: 〈/span〉Almaden Research Center, IBM Research Division, San Jose, CA 95120, USA. heinrich@almaden.ibm.com〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/19251618" target="_blank"〉PubMed〈/a〉
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  • 83
    Publication Date: 2009-01-03
    Description: Dehaene et al. (Reports, 30 May 2008, p. 1217) argued that native speakers of Mundurucu, a language without a linguistic numerical system, inherently represent numerical values as a logarithmically spaced spatial continuum. However, their data do not rule out the alternative conclusion that Mundurucu speakers encode numbers linearly with scalar variability and psychologically construct space-number mappings by analogy.〈br /〉〈br /〉〈a href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3393850/" target="_blank"〉〈img src="https://static.pubmed.gov/portal/portal3rc.fcgi/4089621/img/3977009" border="0"〉〈/a〉   〈a href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3393850/" target="_blank"〉This paper as free author manuscript - peer-reviewed and accepted for publication〈/a〉〈br /〉〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Cantlon, Jessica F -- Cordes, Sara -- Libertus, Melissa E -- Brannon, Elizabeth M -- R37 HD023103/HD/NICHD NIH HHS/ -- New York, N.Y. -- Science. 2009 Jan 2;323(5910):38; author reply 38. doi: 10.1126/science.1164773.〈br /〉〈span class="detail_caption"〉Author address: 〈/span〉Center for Cognitive Neuroscience, Duke University, Durham, NC 27708, USA. jfc2@duke.edu〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/19119201" target="_blank"〉PubMed〈/a〉
    Keywords: Brazil ; Humans ; *Indians, South American ; *Intuition ; *Language ; *Mathematical Concepts
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  • 84
    Publication Date: 2009-12-08
    Description: Fanconi anemia is a human cancer predisposition syndrome caused by mutations in 13 Fanc genes. The disorder is characterized by genomic instability and cellular hypersensitivity to chemicals that generate DNA interstrand cross-links (ICLs). A central event in the activation of the Fanconi anemia pathway is the mono-ubiquitylation of the FANCI-FANCD2 complex, but how this complex confers ICL resistance remains enigmatic. Using a cell-free system, we showed that FANCI-FANCD2 is required for replication-coupled ICL repair in S phase. Removal of FANCD2 from extracts inhibits both nucleolytic incisions near the ICL and translesion DNA synthesis past the lesion. Reversal of these defects requires ubiquitylated FANCI-FANCD2. Our results show that multiple steps of the essential S-phase ICL repair mechanism fail when the Fanconi anemia pathway is compromised.〈br /〉〈br /〉〈a href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2909596/" target="_blank"〉〈img src="https://static.pubmed.gov/portal/portal3rc.fcgi/4089621/img/3977009" border="0"〉〈/a〉   〈a href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2909596/" target="_blank"〉This paper as free author manuscript - peer-reviewed and accepted for publication〈/a〉〈br /〉〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Knipscheer, Puck -- Raschle, Markus -- Smogorzewska, Agata -- Enoiu, Milica -- Ho, The Vinh -- Scharer, Orlando D -- Elledge, Stephen J -- Walter, Johannes C -- GM62267/GM/NIGMS NIH HHS/ -- R01 GM062267/GM/NIGMS NIH HHS/ -- R01 GM062267-09/GM/NIGMS NIH HHS/ -- R37 GM044664/GM/NIGMS NIH HHS/ -- R37 GM044664-23/GM/NIGMS NIH HHS/ -- T32CA09216/CA/NCI NIH HHS/ -- Howard Hughes Medical Institute/ -- New York, N.Y. -- Science. 2009 Dec 18;326(5960):1698-701. doi: 10.1126/science.1182372. Epub 2009 Nov 12.〈br /〉〈span class="detail_caption"〉Author address: 〈/span〉Department of Biological Chemistry and Molecular Pharmacology, Harvard Medical School, Boston, MA 02115, USA.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/19965384" target="_blank"〉PubMed〈/a〉
    Keywords: Animals ; Cell-Free System ; Chromatin/metabolism ; DNA/biosynthesis ; DNA Damage ; *DNA Repair ; *DNA Replication ; Fanconi Anemia/genetics/metabolism ; Fanconi Anemia Complementation Group D2 Protein/*metabolism ; Fanconi Anemia Complementation Group Proteins/*metabolism ; Molecular Sequence Data ; Recombinant Proteins/metabolism ; S Phase ; Signal Transduction ; Ubiquitinated Proteins/metabolism ; Ubiquitination ; Xenopus Proteins/*metabolism ; Xenopus laevis
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  • 85
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    American Association for the Advancement of Science (AAAS)
    Publication Date: 2009-02-21
    Description: 〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Service, Robert F -- New York, N.Y. -- Science. 2009 Feb 20;323(5917):1000-2. doi: 10.1126/science.323.5917.1000.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/19229012" target="_blank"〉PubMed〈/a〉
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  • 86
    Publication Date: 2009-06-23
    Description: The pace of Late Triassic (LT) biodiversity loss is uncertain, yet it could help to decipher causal mechanisms of mass extinction. We investigated relative abundance distributions (RADs) of six LT plant assemblages from the Kap Stewart Group, East Greenland, to determine the pace of collapse of LT primary productivity. RADs displayed not simply decreases in the number of taxa, but decreases in the number of common taxa. Likelihood tests rejected a hypothesis of continuously declining diversity. Instead, the RAD shift occurred over the upper two-to-four fossil plant assemblages and most likely over the last three (final 13 meters), coinciding with increased atmospheric carbon dioxide concentration and global warming. Thus, although the LT event did not induce mass extinction of plant families, it accompanied major and abrupt change in their ecology and diversity.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉McElwain, Jennifer C -- Wagner, Peter J -- Hesselbo, Stephen P -- New York, N.Y. -- Science. 2009 Jun 19;324(5934):1554-6. doi: 10.1126/science.1171706.〈br /〉〈span class="detail_caption"〉Author address: 〈/span〉UCD School of Biology and Environmental Science, University College Dublin, National University of Ireland, Belfield, Dublin 4, Ireland. jennifer.mcelwain@ucd.ie〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/19541995" target="_blank"〉PubMed〈/a〉
    Keywords: *Biodiversity ; Biological Evolution ; *Extinction, Biological ; *Fossils ; Greenland ; Likelihood Functions ; Models, Biological ; *Plants/genetics
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  • 87
    Publication Date: 2009-06-27
    Description: Cosmic rays are the most energetic particles arriving at Earth. Although most of them are thought to be accelerated by supernova remnants, the details of the acceleration process and its efficiency are not well determined. Here we show that the pressure induced by cosmic rays exceeds the thermal pressure behind the northeast shock of the supernova remnant RCW 86, where the x-ray emission is dominated by synchrotron radiation from ultrarelativistic electrons. We determined the cosmic-ray content from the thermal Doppler broadening measured with optical spectroscopy, combined with a proper-motion study in x-rays. The measured postshock proton temperature, in combination with the shock velocity, does not agree with standard shock heating, implying that 〉50% of the postshock pressure is produced by cosmic rays.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Helder, E A -- Vink, J -- Bassa, C G -- Bamba, A -- Bleeker, J A M -- Funk, S -- Ghavamian, P -- van der Heyden, K J -- Verbunt, F -- Yamazaki, R -- New York, N.Y. -- Science. 2009 Aug 7;325(5941):719-22. doi: 10.1126/science.1173383. Epub 2009 Jun 25.〈br /〉〈span class="detail_caption"〉Author address: 〈/span〉Astronomical Institute Utrecht, Utrecht University, Post Office Box 80000, NL-3508 TA Utrecht, Netherlands. e.a.helder@uu.nl〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/19556465" target="_blank"〉PubMed〈/a〉
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  • 88
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    American Association for the Advancement of Science (AAAS)
    Publication Date: 2009-08-29
    Description: 〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Paterson, Bev -- Durrheim, David N -- Tuyl, Frank -- New York, N.Y. -- Science. 2009 Aug 28;325(5944):1071-2; author reply 1072-3. doi: 10.1126/science.325_1071b.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/19713507" target="_blank"〉PubMed〈/a〉
    Keywords: *Disease Outbreaks ; Humans ; *Influenza A Virus, H1N1 Subtype ; Influenza, Human/*epidemiology/*transmission ; *Schools ; United States/epidemiology
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  • 89
    Publication Date: 2009-07-11
    Description: Chemical bonding dynamics are fundamental to the understanding of properties and behavior of materials and molecules. Here, we demonstrate the potential of time-resolved, femtosecond electron energy loss spectroscopy (EELS) for mapping electronic structural changes in the course of nuclear motions. For graphite, it is found that changes of milli-electron volts in the energy range of up to 50 electron volts reveal the compression and expansion of layers on the subpicometer scale (for surface and bulk atoms). These nonequilibrium structural features are correlated with the direction of change from sp2 [two-dimensional (2D) graphene] to sp3 (3D-diamond) electronic hybridization, and the results are compared with theoretical charge-density calculations. The reported femtosecond time resolution of four-dimensional (4D) electron microscopy represents an advance of 10 orders of magnitude over that of conventional EELS methods.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Carbone, Fabrizio -- Kwon, Oh-Hoon -- Zewail, Ahmed H -- New York, N.Y. -- Science. 2009 Jul 10;325(5937):181-4. doi: 10.1126/science.1175005.〈br /〉〈span class="detail_caption"〉Author address: 〈/span〉Physical Biology Center for Ultrafast Science and Technology, Arthur Amos Noyes Laboratory of Chemical Physics, California Institute of Technology, Pasadena, CA 91125, USA.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/19589997" target="_blank"〉PubMed〈/a〉
    Keywords: Crystallization ; Graphite/*chemistry ; Lasers ; *Microscopy, Energy-Filtering Transmission Electron ; *Physicochemical Processes ; *Spectroscopy, Electron Energy-Loss
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  • 90
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    American Association for the Advancement of Science (AAAS)
    Publication Date: 2009-04-25
    Description: 〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Alberts, Bruce -- New York, N.Y. -- Science. 2009 Apr 24;324(5926):463. doi: 10.1126/science.324_463a.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/19390025" target="_blank"〉PubMed〈/a〉
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  • 91
    Publication Date: 2009-12-08
    Description: The beryllium dimer has puzzled chemists for roughly 80 years on account of its unexpectedly strong bonding interaction between two nominally closed-shell atoms. Recent spectroscopic measurements characterized the molecule's ground electronic state with sufficient resolution to distinguish 11 vibrational levels; the possibility that a twelfth level lay just below the dissociation threshold remained unresolved. Here we present a potential function, based on ab initio calculations at the full configuration interaction level, that definitively supports the presence of this twelfth vibrational state. "Morphed" versions of this potential, fitted to experimental data, closely reproduce the observed spectra to within 0.1 cm(-1), bolstering the strength of the assignment.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Patkowski, Konrad -- Spirko, Vladimir -- Szalewicz, Krzysztof -- New York, N.Y. -- Science. 2009 Dec 4;326(5958):1382-4. doi: 10.1126/science.1181017.〈br /〉〈span class="detail_caption"〉Author address: 〈/span〉Department of Physics and Astronomy, University of Delaware, Newark, DE 19716, USA. patkowsk@udel.edu〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/19965753" target="_blank"〉PubMed〈/a〉
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  • 92
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    American Association for the Advancement of Science (AAAS)
    Publication Date: 2009-02-14
    Description: 〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Service, Robert F -- New York, N.Y. -- Science. 2009 Feb 13;323(5916):864. doi: 10.1126/science.323.5916.864.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/19213885" target="_blank"〉PubMed〈/a〉
    Keywords: Animals ; Protein Array Analysis/methods ; *Protein Biosynthesis ; Proteomics/*methods ; RNA, Messenger/metabolism ; Ribosomes/metabolism ; Yeasts
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  • 93
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    American Association for the Advancement of Science (AAAS)
    Publication Date: 2009-01-24
    Description: 〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Wallner, Christian -- New York, N.Y. -- Science. 2009 Jan 23;323(5913):461. doi: 10.1126/science.323.5913.461a.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/19164730" target="_blank"〉PubMed〈/a〉
    Keywords: Editorial Policies ; *Journal Impact Factor ; *Publishing
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  • 94
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    American Association for the Advancement of Science (AAAS)
    Publication Date: 2009-04-04
    Description: 〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Alberts, Bruce -- New York, N.Y. -- Science. 2009 Apr 3;324(5923):13. doi: 10.1126/science.1174131.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/19342554" target="_blank"〉PubMed〈/a〉
    Keywords: *Career Choice ; Education ; Government ; Jurisprudence ; Public Policy ; *Science
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  • 95
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    American Association for the Advancement of Science (AAAS)
    Publication Date: 2009-07-11
    Description: 〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Edgar, Bruce A -- Kim, Kerry J -- New York, N.Y. -- Science. 2009 Jul 10;325(5937):158-9. doi: 10.1126/science.1177203.〈br /〉〈span class="detail_caption"〉Author address: 〈/span〉Fred Hutchinson Cancer Research Center, Seattle, WA 98109, USA. bedgar@fhcrc.org〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/19589991" target="_blank"〉PubMed〈/a〉
    Keywords: Animals ; Cell Cycle ; *Cell Division ; *Cell Enlargement ; Cell Proliferation ; *Cell Size ; Lymphocytes/*cytology ; Saccharomyces cerevisiae/cytology ; Schizosaccharomyces/cytology
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  • 96
    Publication Date: 2009-12-08
    Description: Loss-of-function genetic screens in model organisms have elucidated numerous biological processes, but the diploid genome of mammalian cells has precluded large-scale gene disruption. We used insertional mutagenesis to develop a screening method to generate null alleles in a human cell line haploid for all chromosomes except chromosome 8. Using this approach, we identified host factors essential for infection with influenza and genes encoding important elements of the biosynthetic pathway of diphthamide, which are required for the cytotoxic effects of diphtheria toxin and exotoxin A. We also identified genes needed for the action of cytolethal distending toxin, including a cell-surface protein that interacts with the toxin. This approach has both conceptual and practical parallels with genetic approaches in haploid yeast.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Carette, Jan E -- Guimaraes, Carla P -- Varadarajan, Malini -- Park, Annie S -- Wuethrich, Irene -- Godarova, Alzbeta -- Kotecki, Maciej -- Cochran, Brent H -- Spooner, Eric -- Ploegh, Hidde L -- Brummelkamp, Thijn R -- New York, N.Y. -- Science. 2009 Nov 27;326(5957):1231-5. doi: 10.1126/science.1178955.〈br /〉〈span class="detail_caption"〉Author address: 〈/span〉Whitehead Institute for Biomedical Research, 9 Cambridge Center, Cambridge, MA 02142, USA.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/19965467" target="_blank"〉PubMed〈/a〉
    Keywords: ADP Ribose Transferases/metabolism/toxicity ; Adenosine Diphosphate Ribose/metabolism ; Amino Acid Sequence ; Antigens, Bacterial/metabolism/toxicity ; Bacterial Toxins/*metabolism/toxicity ; Biosynthetic Pathways ; Cell Line, Tumor ; Diphtheria Toxin/metabolism/toxicity ; Exotoxins/metabolism/toxicity ; Genes ; *Genetic Testing ; *Haploidy ; Histidine/analogs & derivatives/biosynthesis ; *Host-Pathogen Interactions ; Humans ; Influenza A Virus, H1N1 Subtype/*pathogenicity ; Molecular Sequence Data ; Monosaccharide Transport Proteins/genetics/metabolism ; Mutagenesis, Insertional ; N-Acylneuraminate Cytidylyltransferase/genetics/metabolism ; Peptide Elongation Factor 2/metabolism ; Proteins/chemistry/genetics/metabolism ; Virulence Factors/metabolism/toxicity
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
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  • 97
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    American Association for the Advancement of Science (AAAS)
    Publication Date: 2009-04-25
    Description: 〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Hemmer, P -- Wrachtrup, J -- New York, N.Y. -- Science. 2009 Apr 24;324(5926):473-4. doi: 10.1126/science.1170912.〈br /〉〈span class="detail_caption"〉Author address: 〈/span〉Electrical and Computer Engineering, Texas A&M University, College Station, TX 77843, USA. prhemmer@ece.tamu.edu〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/19390033" target="_blank"〉PubMed〈/a〉
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
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  • 98
    Publication Date: 2009-12-17
    Description: We present an analytical treatment of a set of coupled kinetic equations that governs the self-assembly of filamentous molecular structures. Application to the case of protein aggregation demonstrates that the kinetics of amyloid growth can often be dominated by secondary rather than by primary nucleation events. Our results further reveal a range of general features of the growth kinetics of fragmenting filamentous structures, including the existence of generic scaling laws that provide mechanistic information in contexts ranging from in vitro amyloid growth to the in vivo development of mammalian prion diseases.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Knowles, Tuomas P J -- Waudby, Christopher A -- Devlin, Glyn L -- Cohen, Samuel I A -- Aguzzi, Adriano -- Vendruscolo, Michele -- Terentjev, Eugene M -- Welland, Mark E -- Dobson, Christopher M -- Wellcome Trust/United Kingdom -- New York, N.Y. -- Science. 2009 Dec 11;326(5959):1533-7. doi: 10.1126/science.1178250.〈br /〉〈span class="detail_caption"〉Author address: 〈/span〉Cavendish Laboratory, University of Cambridge, J. J. Thomson Avenue, Cambridge CB3 0HE, UK.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/20007899" target="_blank"〉PubMed〈/a〉
    Keywords: Amyloid/*chemistry ; Biochemical Processes ; Glutathione Peroxidase/chemistry ; Insulin/chemistry ; Kinetics ; Lactoglobulins/chemistry ; Mathematical Concepts ; Multiprotein Complexes/*chemistry ; Peptide Termination Factors/chemistry ; Peptides/chemistry ; Prions/chemistry ; *Protein Multimerization ; Saccharomyces cerevisiae Proteins/chemistry
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
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  • 99
    Publication Date: 2009-03-17
    Description: Wind-driven upwelling in the ocean around Antarctica helps regulate the exchange of carbon dioxide (CO2) between the deep sea and the atmosphere, as well as the supply of dissolved silicon to the euphotic zone of the Southern Ocean. Diatom productivity south of the Antarctic Polar Front and the subsequent burial of biogenic opal in underlying sediments are limited by this silicon supply. We show that opal burial rates, and thus upwelling, were enhanced during the termination of the last ice age in each sector of the Southern Ocean. In the record with the greatest temporal resolution, we find evidence for two intervals of enhanced upwelling concurrent with the two intervals of rising atmospheric CO2 during deglaciation. These results directly link increased ventilation of deep water to the deglacial rise in atmospheric CO2.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Anderson, R F -- Ali, S -- Bradtmiller, L I -- Nielsen, S H H -- Fleisher, M Q -- Anderson, B E -- Burckle, L H -- New York, N.Y. -- Science. 2009 Mar 13;323(5920):1443-8. doi: 10.1126/science.1167441.〈br /〉〈span class="detail_caption"〉Author address: 〈/span〉Lamont-Doherty Earth Observatory of Columbia University, Post Office Box 1000, Palisades, NY 10964, USA. boba@ldeo.columbia.edu〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/19286547" target="_blank"〉PubMed〈/a〉
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    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
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  • 100
    Publication Date: 2009-11-07
    Description: Ecological speciation occurs when ecologically based, divergent selection causes the evolution of reproductive isolation. There are many empirical examples of this process; however, there exists a poorly characterized stage during which the traits that distinguish species ecologically and reproductively segregate in a single population. By using a combination of genetic mapping, mate-choice experiments, field observations, and population genetics, we studied a butterfly population with a mimetic wing color polymorphism and found that the butterflies exhibited partial, color-based, assortative mate preference. These traits represent the divergent, ecologically based signal and preference components of sexual isolation that usually distinguish incipient and sibling species. The association between behavior and recognition trait in a single population may enhance the probability of speciation and provides an example of the missing link between an interbreeding population and isolated species.〈br /〉〈br /〉〈a href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2875868/" target="_blank"〉〈img src="https://static.pubmed.gov/portal/portal3rc.fcgi/4089621/img/3977009" border="0"〉〈/a〉   〈a href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2875868/" target="_blank"〉This paper as free author manuscript - peer-reviewed and accepted for publication〈/a〉〈br /〉〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Chamberlain, Nicola L -- Hill, Ryan I -- Kapan, Durrell D -- Gilbert, Lawrence E -- Kronforst, Marcus R -- GM068763/GM/NIGMS NIH HHS/ -- P50 GM068763/GM/NIGMS NIH HHS/ -- P50 GM068763-06/GM/NIGMS NIH HHS/ -- New York, N.Y. -- Science. 2009 Nov 6;326(5954):847-50. doi: 10.1126/science.1179141.〈br /〉〈span class="detail_caption"〉Author address: 〈/span〉Faculty of Arts and Sciences Center for Systems Biology, Harvard University, Cambridge, MA 02138, USA.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/19892982" target="_blank"〉PubMed〈/a〉
    Keywords: Amplified Fragment Length Polymorphism Analysis ; Animals ; Butterflies/anatomy & histology/*genetics/*physiology ; Color ; Ecosystem ; Female ; Genes, Insect ; Genetic Linkage ; *Genetic Speciation ; Linkage Disequilibrium ; Male ; *Mating Preference, Animal ; Molecular Sequence Data ; Phenotype ; *Pigmentation/genetics ; *Polymorphism, Genetic ; Reproduction ; Selection, Genetic ; Wings, Animal/*anatomy & histology
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
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