ALBERT

All Library Books, journals and Electronic Records Telegrafenberg

X
feed icon rss

Your email was sent successfully. Check your inbox.

An error occurred while sending the email. Please try again.

Proceed reservation?

Export
Filter
  • Humans  (1,488)
  • Cell & Developmental Biology
  • Fisheries
  • 2010-2014  (1,512)
  • 1960-1964
  • 2013  (1,512)
Collection
Keywords
Publisher
Years
  • 2010-2014  (1,512)
  • 1960-1964
Year
  • 1
    facet.materialart.
    Unknown
    Going against the flow: Effects of river damming in Cuban fisheries (2013)
    Details
    Publication Date: 2021-05-19
    Description: Over the last decade eutrophication of freshwater artificial reservoirs in Cuba occurred in parallel to oligotrophication of estuarine and coastal waters. These two processes influenced both freshwater and marine fisheries. A dramatic shift in species composition in freshwater fisheries has occurred, from dominance by cichlids (tilapia) to dominance by cyprinids. The high fishery yield from some reservoirs, and shift in species composition, seems related to progressive eutrophication of reservoirs by nutrient subsidies from different anthropogenic activities; particular those related to the size of urban areas within their watersheds. On the other hand, marine landings of estuarine-dependent species declined more significantly than for other groups associated with seagrass beds–coral reefs and oceanic waters. The ratio between catches of estuarine-dependent species and those associated with seagrass beds and coral reefs, decreased significantly over the last 20 years. The decrease in landings was more evident in typical estuarine species, such as shrimps (Litopenaeus schmitti and Farfantopenaeus notialis), mangrove oyster (Crassostrea rhizophorae) and mullets (Mugil spp.). River damming increased during the same period and is significantly correlated with these decreases. It is hypothesized that two different processes acted synergistically, leading to dramatic decreases of several orders of magnitude, in the catches of estuarine species over the last decade: the trapping of nutrients and sediments by river damming, and a drastic reduction in nutrient inputs from land-based sources due to reduced fertilizer use. These are postulated to have affected not only estuarine resources, but also the whole coastal ecosystem.
    Description: Durante la última década, la eutrofización de los embalses artificiales de agua dulce en Cuba se produjo en paralelo a oligotrophication de estuarios y costeras aguas. Estos dos procesos de influencia de agua dulce y la pesca marina. Un cambio dramático en la composición de las especies en la pesca de agua dulce se ha producido, de la dominación de los cíclidos (tilapia) a la dominación de ciprínidos. La alta producción de la pesca de algunos embalses, y el cambio en las especies composición, parece relacionada con la progresiva eutrofización de los embalses de las subvenciones de nutrientes de diferentes actividades antropogénicas, especialmente las relacionado con el tamaño de las zonas urbanas dentro de sus cuencas. Por otro lado, los desembarques de especies marinas de estuario-dependientes disminuyeron significativamente más que para otros grupos asociados con algas marinas Los arrecifes de coral-camas y las aguas oceánicas. La relación entre las capturas de las especies que dependen de los estuarios y las asociadas a las praderas marinas y Los arrecifes de coral, se redujo significativamente en los últimos 20 años. La disminución en los desembarques fue más evidente en especies típicas de estuarios, tales como camarones (Litopenaeus schmitti y Farfantopenaeus notialis), ostra de mangle (Crassostrea rhizophorae) y la lisa (Mugil spp.). El represamiento del Río aumentó durante el mismo período y se correlaciona significativamente con estas disminuciones. Se planteó la hipótesis de que dos procesos diferentes actúan de forma sinérgica, que conduce a una disminución drástica de varios órdenes de magnitud, en las capturas de las especies de estuario en la última década: la captura de nutrientes y sedimentos por represas río, y una reducción drástica de los aportes de nutrientes de fuentes terrestres, debido a la reducción del uso de fertilizantes. Se postula que han afectado no sólo a los recursos estuarinos, sino también todo el ecosistema costero.
    Description: Published
    Description: ríos
    Description: impactos antropogénicos
    Keywords: river ; Fisheries ; Eutrophication
    Repository Name: AquaDocs
    Type: Journal Contribution , Refereed , Article
    Location Call Number Expected Availability
    BibTip Others were also interested in ...
    PAPER (OA)
  • 2
    facet.materialart.
    Unknown
    Capturas de sierras, serruchos y pintadas con redes de enmalles (2013)
    Details
    Publication Date: 2021-05-19
    Description: Se muestra la evolución de las capturas de las sierras y pintadas, se describen las 3 maneras en que las especies pueden quedar atrapadas en la redes de enmalles, así como también los tipos de redes (deriva, media agua y de fondo).
    Description: Published
    Description: Scomberomorus regalis
    Description: Scomberomorus maculatus
    Description: Scomberomorus cavalla
    Description: spanish mackerel
    Description: king mackerel
    Description: painted mackerel
    Description: enmalle
    Description: arte de pesca
    Keywords: Fisheries ; Artisanal fishing
    Repository Name: AquaDocs
    Type: Journal Contribution , Refereed , Article
    Location Call Number Expected Availability
    BibTip Others were also interested in ...
    PAPER (OA)
  • 3
    facet.materialart.
    Unknown
    Las pesquerías de lisas y mojarras en lagunas costeras. (2013)
    Details
    Publication Date: 2021-05-19
    Description: Published
    Description: Mugil curema
    Description: Mugil liza
    Description: Mugil cephalus
    Description: Gerres cinereus
    Description: patao
    Description: coastal lagoons
    Keywords: Mullet fisheries ; Fisheries
    Repository Name: AquaDocs
    Type: Journal Contribution , Refereed , Article
    Location Call Number Expected Availability
    BibTip Others were also interested in ...
    PAPER (OA)
  • 4
    facet.materialart.
    Unknown
    Suivi de l’activité de la pêche hauturière dans le gouvernorat de Medenine (sud de la Tunisie). (2013)
    INSTM, Institut national des sciences et technologies de la mer | Tunis
    Details
    Publication Date: 2021-05-19
    Description: Ce travail représente une contribution à l'étude de l'activité de pêche hauturière dans le gouvernorat de Médenine, particulièrement, au niveau du port de Zarzis ; durant la période (juin 2005-juin 2006). Il consiste à réaliser, grâce à des enquêtes menées au port, deux types d'analyses : une analyse quantitative afin de déterminer les débarquements saisonniers moyens des espèces les plus débarquées par la pêche hauturière et une analyse qualitative pour établir les structures démographiques des espèces les plus exploitées dans la région. Les résultats obtenus ont montré que, durant la période d'étude, les principales espèces débarquées par la pêche hauturière sont la sardinelle, le maquereau, le saurel, le rouget blanc, le pageot, la thonine, la seiche et la crevette royale. En examinant les débarquements saisonniers moyens des espèces les plus débarquées par type de pêche, nous avons remarqué que deux ou trois espèces dominent pour chaque saison. De plus, l'analyse des structures démographique des apports a montré que la majorité des individus débarqués sont matures, à l’exception du maquereau dont les captures sont constituées d’individus immatures, surtout pendant les saisons d’été et d’automne.
    Description: This work represents a contribution to the study of the offshore fishing activity in the governorate of Medenine, particularly at the port of Zarzis, during the period (june 2005-june 2006. It is to realize, through surveys conducted at the port, two types of analyzes: a quantitative analysis to determine the average seasonal landings of most landed species by fishing offshore units and qualitative analysis to determine the demographic structure of the most exploited species in the region. The obtained results showed that during the period of study, the main landed species by offshore fishing are sardinella, mackerel, horse mackerel, white mullet, sea bream, skipjack tuna, cuttlefish and the caramote prawn. By examining the average seasonal landings of the most landed species, we noticed that, for each season, two or three species dominate. Furthermore, analysis of demographic structures of the landings showed that the majority of landed individuals are mature, with the exception of mackerel catches which are composed of immature individuals, especially during the seasons of summer and autumn.
    Description: Published
    Description: analyse qualitative
    Description: pêche hauturière
    Keywords: Quality analysis ; Offshore ; Fisheries
    Repository Name: AquaDocs
    Type: Proceedings Paper , Refereed , Meeting abstract
    Location Call Number Expected Availability
    BibTip Others were also interested in ...
    PAPER (OA)
  • 5
    facet.materialart.
    Unknown
    Las pesquerías con nasas de placer, tranques y chinchorros (2013)
    Details
    Publication Date: 2021-05-19
    Description: Se muestran las capturas históricas de la biajaiba (1935-2000), la evolución de las capturas del pargo (una de las especies de mayor interés económico en Cuba). Se evalúa la utilización de éstas artes de pesca en especies comerciales y su implicación con daños al medio ambiente. Se tiene en cuenta que los pargos criollos, la biajaiba y el caballerote representan el 20 % de las capturas.
    Description: Published
    Description: pesquería artesanal
    Description: cubera
    Description: cherna criolla
    Description: pesca del alto
    Description: pargo
    Description: rabirrubia
    Description: caballerote
    Description: biajaiba
    Keywords: Fisheries ; Artisanal fishing
    Repository Name: AquaDocs
    Type: Journal Contribution , Non-Refereed , Article
    Location Call Number Expected Availability
    BibTip Others were also interested in ...
    PAPER (OA)
  • 6
    facet.materialart.
    Unknown
    Historical development of Cuban fisheries: why we need an integrated approach to fisheries management? (2013)
    Gulf and Caribbean Fisheries Institute
    Details
    Publication Date: 2021-05-19
    Description: Un análisis de los datos arqueológicos e históricos sobre la pesca en Cuba muestra que el impacto de la población aborigen sobre los recursos pesqueros no fue significativo debido a su baja densidad poblacional y a las tecnologías de pesca. El interés por el oro, el tamaño de la población, las limitaciones tecnológicas para la pesca y preservación de las capturas así como las preferencias dietéticas de los españoles todas indican que la pesca tampoco fue una actividad económica importante durante los tres siglos que siguieron a la llegada de Colón. Las preferencias por la carne de res y el bacalao salado y la baja tasa de crecimiento poblacional durante el período colonial determinaron que la mayor parte de los recursos pesqueros, con la excepción del manatí y las tortugas marinas, permanecieran prácticamente inexplorados durante varios siglos después de la Conquista. Los datos estadísticos e históricos revelan que la pesca experimentó un rápido crecimiento desde 1950 y este patrón parece ser una característica común en el Caribe así como en otras partes del mundo. Las presiones sobre la vida marina fueron más evidentes en la segunda mitad del siglo xx cuando el crecimiento poblacional, las mejoras tecnológicas y las demandas del mercado aceleraron el sector pesquero así como la urbanización en la mayoría de los países del caribe.
    Description: Published
    Keywords: Integrated management ; Fisheries
    Repository Name: AquaDocs
    Type: Proceedings Paper , Refereed , Article
    Location Call Number Expected Availability
    BibTip Others were also interested in ...
    PAPER (OA)
  • 7
    facet.materialart.
    Unknown
    The differential effects of changing management regimes on yields from two fisheries exploiting the same resources (2013)
    Details
    Publication Date: 2021-05-19
    Description: A yield per recruit model has been used to compare the effects of mesh size increment on the yields and revenues of the fisheries of Cameroon under two different cases. Case 1 assumes the commercial fishery to move from the exploitation of three age-groups to two age-groups with no interactions with the artisanal fishery, whereas Case 2 takes into account these interactions. The difference in the percentage increase of yield per recruit between case 1 and case 2 is 61% at current fishing (46% and 18% yield per recruit increment in cases 1 and 2 respectively). The usually accepted long-term yield per recruit increment with increase of age at first capture (with a single non-interacting fisheries) is, in this case, cancelled out. However, the revenues increase by 72% and 63% in cases 1 and 2 respectively. Therefore the economic approach, compared with purely biological analyses, is more convincing. In general, as fisheries always interact, a single-fishery management approach should not be the rule as it is at present; management strategies should consider interactions between different fisheries and be based on their economic performances and not, as said earlier, on purely biological considerations. This is because a biological approach to fisheries management will, at best, be modified by economic factors, or, at worst, be ignored totally in favour of economic policies.
    Description: Published
    Keywords: Biology ; Fisheries ; Biological interaction ; Sciaenidae ; Fisheries development ; Fishery management ; Yield/recruit ; Commercial fisheries ; Artisanal fishing
    Repository Name: AquaDocs
    Type: Journal Contribution , Refereed , Article
    Location Call Number Expected Availability
    BibTip Others were also interested in ...
    PAPER (OA)
  • 8
    facet.materialart.
    Unknown
    Quelles stratégies de suivi, contrôle et surveillance des ressources halieutiques en cogestion locale ? Etude de cas: la surveillance participative au niveau des sites pilotes du programme GIRMaC (2013)
    Details
    Publication Date: 2021-05-19
    Description: La pêche au Sénégal joue un rôle économique et social très important par une contribution globale de près de 11% du PIB primaire et 2,3% du PIB total. Elle occupe de façon directe et indirecte environ 600 000 personnes, soit près de 17% de la population active selon la DP M. Cependant ces dernières décennies, les études ont montré que le secteur traverse une crise aiguë se traduisant par une raréfaction croissante des ressources, notamment les espèces nobles qui ont une forte valeur commerciale. Cette crise est due entre autres à une surexploitation de ces ressources qui est le résultat d’un manque de maîtrise de l’effort de pêche surtout pour les pêcheries artisanales (80% des débarquements et plus de 60% des approvisionnements des industries de la place) au regard du volume de ressources disponibles. Ce manque de maîtrise est dû essentiellement par un défaut du suivi contrôle et surveillance au niveau de la pêche artisanale par l’Etat, qui n’a pas les moyens humains et matériels pour appliquer des mesures de gestion, qui pour la plupart ne sont pas adaptées aux réalités des acteurs à la base. L’objet de cette étude est d’analyser une nouvelle approche axée sur la surveillance participative basée sur l’émergence d’initiatives locales de cogestion au niveau des quatre (04) sites du programme GIRMaC que sont ; Ouakam, Ngaparou, Foundiougne et Bétenty. Il ressort de cette étude que : • Le secteur de la pêche traverse une crise aiguë due principalement selon les acteurs à un défaut de suivi, contrôle et surveillance tel que appliqué actuellement ; • L’approche de cogestion avec des bases juridiques cohérentes, comme le propose le programme GIRMaC peut être un moyen viable pour solutionner à la crise que traverse la pêche ; • D’une part le système Suivi Contrôle et Surveillance coûte cher, d’autre part que ces coûts sont fortement amoindris lorsque les acteurs participent à l’effort de surveillance, par une démarche de surveillance participative en cogestion.
    Description: Président : Omar Thiom THIAW, Professeur UCAD Membres : • Niokhor DIOUF, Chercheur IUPA. • Luis Tito Morais, Chercheur IRD Dakar. • Djiby THIAM, Chercheur GIRMac
    Description: Published
    Description: surveillance; contrôle; cogestion; effort de pêche; pêcherie; surexploitation; biodiversité; pêche artisanale
    Keywords: Ocean surveillance ; Ecosystem management ; Fishing effort ; Overexploitation ; Biodiversity ; Artisanal fishing ; Fisheries
    Repository Name: AquaDocs
    Type: Theses and Dissertations , Master thesis
    Format: 87
    Location Call Number Expected Availability
    BibTip Others were also interested in ...
    PAPER (OA)
  • 9
    facet.materialart.
    Unknown
    Déscription de l'activité ds flotilles pélagiques industrielles en 1986 dans la ZEEM mauritanienne (2013)
    Details
    Publication Date: 2021-05-19
    Description: Published
    Description: espéces pélagiques
    Description: sardine
    Description: pêche industrielle
    Keywords: Fisheries ; Pelagic fisheries ; Industrial fish ; Fish products ; Fishing industry ; Fishing fleet
    Repository Name: AquaDocs
    Type: Journal Contribution , Non-Refereed , Article
    Location Call Number Expected Availability
    BibTip Others were also interested in ...
    PAPER (OA)
  • 10
    facet.materialart.
    Unknown
    Chaine froide dans la conservation du poisson (2013)
    Details
    Publication Date: 2021-05-19
    Description: Unpublished
    Description: conservation
    Description: chaine froide
    Description: poisson
    Keywords: Food conservation ; Fisheries ; Fish conversion ; Conservation (fishery products) ; Glass ; Fisheries
    Repository Name: AquaDocs
    Type: Journal Contribution , Non-Refereed , Article
    Location Call Number Expected Availability
    BibTip Others were also interested in ...
    PAPER (OA)
  • 11
    facet.materialart.
    Unknown
    La pêche des senneurs dans la Baie du Lévrier en 1971 (2013)
    Details
    Publication Date: 2021-05-19
    Description: Published
    Description: Pêche
    Description: Senneur
    Keywords: Seining ; Fisheries ; Fisheries ; Seiners
    Repository Name: AquaDocs
    Type: Journal Contribution , Refereed , Article
    Location Call Number Expected Availability
    BibTip Others were also interested in ...
    PAPER (OA)
  • 12
    facet.materialart.
    Unknown
    Etat des lieux de la filière de transformation artisanale des produits halieutiques au Sénégal (2013)
    Details
    Publication Date: 2021-05-19
    Description: ACDI;CRDI; République Française, Ministère des Affaires Etrangéres; CDE; Enda Graf Sahel;
    Description: Conseil Info MPEA, Projer d'Accés à l'information et au Conseil pour les microet petites entreprises agroalimentaires; Projet d'Appui aux Opérateurs/trices de l'Agroalimentaires (PAOA); Cintech Agroalimentaire; Groupe de Recherche et d'Echanges Technologiques (GRET); Enda GRaf Sahel; SNC-LAVALIN International
    Description: Published
    Description: transformation; transformation artisanale; échantillonage; collecte de données; commercialisation
    Keywords: Processing fishery products ; Biological sampling ; Data collections ; Marketing and distribution ; Fisheries
    Repository Name: AquaDocs
    Type: Theses and Dissertations , Master thesis
    Format: 41
    Location Call Number Expected Availability
    BibTip Others were also interested in ...
    PAPER (OA)
  • 13
    facet.materialart.
    Unknown
    Pêcherie démersale côtière au Sénégal. Essai de modélisation de la dynamique de l'exploitation des stocks (2013)
    Details
    Publication Date: 2021-05-19
    Description: Français - Les traits essentiels de la côte sénégalaise, repères historiques de la pêche, communautés de pêcheurs, caractéristiques des flottes et modes d’accès à la ressource et d’interaction sont analysés. Les caractéristiques, tendances décroissantes de l’abondance,niveaux d’exploitation, mesures d’aménagement, relations interspécifiques, changements potentiels et sources de variation des stocks démersaux côtiers sont précisés. Les notions de tactiques et stratégies de pêche sont passées en revue, conceptualisées puis étudiées.Le modèle «Dynamique Conjointe Exploitation Ressource» utilisé repose sur la définition de 4 typologies. L’utilisation de méthodes de classification et de connaissances d’experts conduit à considérer 32 stocks, 31 strates, 82 tactiques et 25 flottilles artisanales et chalutières. Les typologies sont articulées avec la prise en compte de paramètres relatifs à l’économie, aux stocks, flottilles et règles de décisions. L’ajustement est satisfaisant en partie. Toutefois, le modèle garde son importance en matière de prospective et d’objectifs à atteindre via la définition de variables de contrôle. Notre travail peut être considéré comme une esquisse invitant à un groupe de travail élargi aux experts des institutions halieutiques nationales voire, sous-régionales. Des propositions sont faites sur les bases de données, les licences de pêche et l’étude des tactiques et stratégies à mener suivant des pas de temps raisonnables pour tenir compte du grand dynamisme des pêcheries. Dès lors qu'il s’agit de caractériser l'impact de la pêche sur l'écosystème, ces travaux sont des éléments essentiels des recherches à faire sur la dynamique des écosystèmes exploités. English - The essential features of the Senegalese coast, fisheries history, fishermen's communities, artisanal and trawling fleet’s characteristics and their way of accessing to the resource and interactions are described. The characteristics, evolutionary tendencies of abundance, level of exploitation, measures of fisheries management, interspecific relationship, potential evolutionary changes and sources of variation of coastal demersal stocks are specified. Tactics and strategies are reviewed, conceptualized and studied. We used the model "Dynamique Conjointe Exploitation Ressource" which lies on 32 stocks, 31 strata, 82 tactics, 25 fleets and several other parameters dealing with stocks, fleets, economy and making decision rules. The adjustment is partially satisfactory but the model is of great interest for prospective studies and objectives to reach once defined variables of control. Our work is an outline calling for an enlarged working group implying national or sub regional fisheries institutional experts. Tactics and strategies studies, re-actualized in artisanal fisheries, are performed for the first time in industrial fisheries. The typological approach is simple, pertinent, efficacy and fast. Propositions are made relatively to databases, fishing licenses and tactics and strategies studies that should be implemented according to a reasonable time steps in order to take into account the big dynamism of the Senegalese fisheries. As it is intended to characterize fisheries impact on ecosystem, these works are one of essential research elements on the dynamic of exploited ecosystems.
    Description: Published
    Description: pêcherie; démersale côtière; modélisation; stocks; écosystème; communauté de pêcheurs; eaux continentales; eaux marines; saison hydrologique; pêcheur; flottille; crevettier; capture; aménagement des pêcheries; pêche chalutière; pêche artisanale; licence de pêche; permis de pêche
    Keywords: Fisheries ; Demersal fisheries ; Modelling ; Stocks ; Ecosystems ; Community fishing ; Inland waters ; Marine water ; Hydrologic cycle ; Fishermen ; Fishing fleet ; Shrimp fisheries ; Capture fisheries ; Fisheries management ; Trawling ; Artisanal fishing ; Fishing licenses
    Repository Name: AquaDocs
    Type: Theses and Dissertations , Bachelor thesis
    Format: 234
    Location Call Number Expected Availability
    BibTip Others were also interested in ...
    PAPER (OA)
  • 14
    facet.materialart.
    Unknown
    Traitement traditionnel et conservation des produits de la pêche en Mauritanie (2013)
    Details
    Publication Date: 2021-05-19
    Description: Published
    Description: conservation
    Description: produits
    Description: pêche
    Keywords: Conservation ; Fisheries ; Fish products
    Repository Name: AquaDocs
    Type: Journal Contribution , Non-Refereed , Article
    Location Call Number Expected Availability
    BibTip Others were also interested in ...
    PAPER (OA)
  • 15
    facet.materialart.
    Unknown
    Habitat damage, marine reserves, and the value of spatial management (2013)
    Ecological Society of America
    Details
    Publication Date: 2022-05-25
    Description: Author Posting. © Ecological Society of America, 2013. This article is posted here by permission of Ecological Society of America for personal use, not for redistribution. The definitive version was published in Ecological Applications 23 (2013): 959–971, doi:10.1890/12-0447.1.
    Description: The biological benefits of marine reserves have garnered favor in the conservation community, but “no-take” reserve implementation is complicated by the economic interests of fishery stakeholders. There are now a number of studies examining the conditions under which marine reserves can provide both economic and ecological benefits. A potentially important reality of fishing that these studies overlook is that fishing can damage the habitat of the target stock. Here, we construct an equilibrium bioeconomic model that incorporates this habitat damage and show that the designation of marine reserves, coupled with the implementation of a tax on fishing effort, becomes both biologically and economically favorable as habitat sensitivity increases. We also study the effects of varied degrees of spatial control on fisheries management. Together, our results provide further evidence for the potential monetary and biological value of spatial management, and the possibility of a mutually beneficial resolution to the fisherman–conservationist marine reserve designation dilemma.
    Description: M. G. Neubert acknowledges the support of the National Science Foundation (DMS-0532378, OCE-1031256) and a Thomas B. Wheeler Award for Ocean Science and Society. H. V. Moeller acknowledges support from a National Science Foundation Graduate Research Fellowship. This research is based in part on work supported by Award No. USA 00002 made by King Abdullah University of Science and Technology (KAUST).
    Keywords: Bioeconomics ; Destructive fishing practices ; Fisheries ; Habitat damage ; Marine protected areas ; Marine reserves ; Optimal control ; Optimal harvesting ; Spatial management
    Repository Name: Woods Hole Open Access Server
    Type: Article
    Format: application/pdf
    Location Call Number Expected Availability
    BibTip Others were also interested in ...
    PAPER (OA)
  • 16
    facet.materialart.
    Unknown
    Projet pour le développement rationnel et durable du secteur de la pêche au Sénégal (INT/07/16M/SPA) (2013)
    Ministerio de Medio Ambiente y Medio Rural y Marino | Madrid (Espagne)
    Details
    Publication Date: 2021-05-19
    Description: Description du secteur de la pêche Avec la Mauritanie, le Sénégal est de loin le plus grand producteur de produits de pêche de la sous région. Avec 718 km de cote et un territoire maritime de 198km2, 15 745 km2 de superficie fluviale, 2 estuaires, des mangroves et un lac de 350km2, le Sénégal possède tous les atouts des plus grands producteurs de pêche. Le potentiel annuel de captures s’élève à 500 000 tonnes. Le secteur a subi une croissance spectaculaire ces trente dernières années : les débarquements sont passés 50 000 tonnes en 1965 à plus de 450 000 en 1997. Le secteur se compose principalement de deux sous-secteurs : la pêche industrielle et la pêche traditionnelle ou artisanale. Cette dernière, vielle de plusieurs siècles a su s’adapter et se moderniser au cours des dernières décennies. La flotte de pêche artisanale est dynamique et diversifiée ; selon les estimations, en 2005 il y avait plus de 13 000 pirogues. La pêche artisanale se concentre dans sept régions maritimes et fluviales du pays: Dakar, Thiès, Saint Louis, Fatick, Zinguinchor, Louga et Kaolack. Le port de Kayar dans la région de Thiès correspond à la principale zone de débarquement de la pêche artisanale avec environ 70% des débarquements. Dans le secteur industriel, les pêcheurs travaillent à bord d’une flottille de petits sardiniers, de 143 chalutiers destinés à la pêche d’espèces demersales, de 3 sardiniers et de 42 thoniers. Alors que le Sénégal domine largement le sous-secteur demersale avec 70% des chalutiers opérants, le pays ne possède que 6 thoniers contre 38 étrangers, dont une partie seulement des captures est débarquée au Sénégal. La pêche industrielle est concentrée autour de la capitale dans le Port autonome de Dakar et des ports secondaires de Saint Louis, Kaolack et Ziguinchor. Aujourd’hui, le secteur de la pêche sénégalaise est largement dominé par la pêche artisanale, qui constituait 90% des cargaisons totales des produits de la mer en 2006 avec 350 000 tonnes. Plus de 60% des produits de la pêche artisanale sont destinés à l’exportation et la transformation. En 2006, le secteur dans son ensemble représentait 9% du PIB du secteur primaire, 1.5% du PIB total, et 1/3 des devises étrangères (250 millions de dollars par an). Plus importante que le poids économique du secteur, est son poids social : la pêche génère indirectement 600 000 emplois, dont 67% au sein du secteur artisanal. En outre, les produits de la pêche comblent les besoins en protéines animales de la population sénégalaise à hauteur de 75%1. La pêche a connu une expansion spectaculaire au cours des dernières décennies grâce à l’impulsion de politiques publiques de développement basées sur une logique sectorielle productiviste. Une flotte nationale artisanale et industrielle a été progressivement mise en place ainsi que de fortes capacités de transformation industrielle. Cet engagement de l’Etat a ensuite connu un net ralentissement du fait, entre autre, des politiques d’ajustement structurel. Le renchérissement des coûts de production subséquents à la dévaluation du franc CFA en 1994 a lourdement affecté les pêcheurs. Parallèlement, avec la forte demande en produits halieutiques et en l’absence de politiques adéquates et cohérentes de gestion durable des ressources exploitables, une situation de surexploitation des ressources halieutiques s’est installée. En conséquence de la raréfaction des ressources halieutiques, la pêche sénégalaise traverse une crise sans précédent, dont les effets commencent à se faire sentir à tous les niveaux : appauvrissement des communautés de pêcheurs, menace de l’approvisionnement en poisson des populations, baisse des captures à haute valeur ajoutée, baisse des exportations, baisse de la rentabilité et des revenus des unités de pêche. Par ailleurs, de plus en plus d’établissements de transformation industrielle ferment (23 entreprises entre 1999 et 2006).
    Description: Ministerio de Medio Ambiente Y Medio Rural y Marino
    Description: Pablo Manuel Xandri Royo CTP Proyecto (INT/07/16M/SPA) Este trabajo se ha realizado en el marco del Convenio de Colaboración entre el actual Ministerio de Medio Ambiente y Medio Rural y Marino de España y la Organización Internacional del Trabajo de 28 de diciembre de 2007
    Description: Published
    Description: environnement; socio-économie; pêche; capture; débarquement; engin de pêche; femme; pêcheur; convention internationale; réglementation
    Keywords: Fisheries ; Marine environment ; Socioeconomic aspects ; Capture fisheries ; Landing statistics ; Fishing gear ; Women ; Fishermen ; Conventions ; Fishery regulations
    Repository Name: AquaDocs
    Type: Report , Non-Refereed
    Format: 208
    Location Call Number Expected Availability
    BibTip Others were also interested in ...
    PAPER (OA)
  • 17
    facet.materialart.
    Unknown
    Le secteur des pêches au Sénégal: tendances, enjeux et orientations politiques (2013)
    Programme Kurukan Fugan (Union Européenne/Gouvernement du Sénégal/Enda Graf/Gret) | Dakar (Sénégal)
    Details
    Publication Date: 2021-05-19
    Description: Programme KURUKAN FUGAN (Union Européenne/Gouvernement du Sénégal/EndaGraf/GRET)
    Description: Published
    Description: politique de pêche; environnement marin; socio-économie; co-gestion; aquaculture; pêche artisanale; pêche industrielle; pêcherie; ONG; AMP; ressource halieutique; organisations professionnelles
    Keywords: Marine environment ; Socioeconomic aspects ; Fishery management ; Aquaculture ; Artisanal fishing ; Fisheries ; Industrial fish ; Fishery resources ; Fishing policy ; Protected areas ; Professionals
    Repository Name: AquaDocs
    Type: Book , Non-Refereed , Article
    Format: 26
    Location Call Number Expected Availability
    BibTip Others were also interested in ...
    PAPER (OA)
  • 18
    facet.materialart.
    Unknown
    La pesca en Cuba : apuntes para su historia (II) : la pesca desde 1492 hasta 1902 : etapa colonial (2013)
    Details
    Publication Date: 2021-09-18
    Description: En la época colonial algunas especies de peces cubanos retienen sus nombres por los cuales eran conocidos por los aborígenes: biajaca, biajaiba, cojinúa, jiguagua, cibí. Aún hoy se designan de igual forma. En esta época aparece la primera obra científica impresa en Cuba, los primeros pueblos pescadores y los primeros científicos.
    Description: Published
    Keywords: Fisheries
    Repository Name: AquaDocs
    Type: Journal Contribution , Refereed , Article
    Location Call Number Expected Availability
    BibTip Others were also interested in ...
    PAPER (OA)
  • 19
    facet.materialart.
    Unknown
    La pesca en Cuba : apuntes para su historia (I) : la pesca en las comunidades primitivas : etapa precolombina (2013)
    Details
    Publication Date: 2021-09-18
    Description: Published
    Description: especies nativas
    Description: pesca
    Keywords: Fisheries ; Indigenous species ; Indigenous fishing
    Repository Name: AquaDocs
    Type: Journal Contribution , Refereed , Article
    Location Call Number Expected Availability
    BibTip Others were also interested in ...
    PAPER (OA)
  • 20
    facet.materialart.
    Unknown
    La pesca en Cuba : apuntes para su historia (III) : la pesca desde 1902 hasta 1952 : etapa de la seudorrepública (2013)
    Details
    Publication Date: 2021-09-18
    Description: Published
    Keywords: Fisheries
    Repository Name: AquaDocs
    Type: Journal Contribution , Refereed , Article
    Location Call Number Expected Availability
    BibTip Others were also interested in ...
    PAPER (OA)
  • 21
    facet.materialart.
    Unknown
    La Pesca de los peces de pico en Cuba (I) (2013)
    Details
    Publication Date: 2021-09-18
    Description: Recuento en forma breve de las pesquerías de estas especies durante varios siglos, en los cuales los sabios Parra y Felipe Poey ofrecen descripciones. Precios, lugares de captura y pescadores son los protagonistas.
    Description: Published
    Description: Emperador-Xiphias gladius
    Description: pez espada
    Description: castero-Makaira nigricans
    Description: aguja blanca-Tetrapturus albidus
    Keywords: Fisheries ; Fishes
    Repository Name: AquaDocs
    Type: Journal Contribution , Non-Refereed , Article
    Location Call Number Expected Availability
    BibTip Others were also interested in ...
    PAPER (OA)
  • 22
    facet.materialart.
    Unknown
    La pesca de los peces de pico en Cuba (II). (2013)
    Details
    Publication Date: 2021-09-18
    Description: Causas del descenso en las pesquerías de estas especies a partir de 1975. Se describen las técnicas y artes de pesca empleadas y se abunda en la complejidad de las capturas y las características de los palangres empleados para cada especie. Una comparación es establecida además con países del área. De forma muy didáctica e instructiva.
    Description: Published
    Description: castero-Makaira nigricans
    Description: Emperador-Xiphias gladius
    Description: aguja blanca-Tetrapturus albidus
    Keywords: Fisheries ; Fishes
    Repository Name: AquaDocs
    Type: Journal Contribution , Non-Refereed , Article
    Location Call Number Expected Availability
    BibTip Others were also interested in ...
    PAPER (OA)
  • 23
    facet.materialart.
    Unknown
    Modelling the effects of subjective and objective decision making in scientific peer review (2013)
    Nature Publishing Group (NPG)
    Details
    Publication Date: 2013-12-07
    Description: The objective of science is to advance knowledge, primarily in two interlinked ways: circulating ideas, and defending or criticizing the ideas of others. Peer review acts as the gatekeeper to these mechanisms. Given the increasing concern surrounding the reproducibility of much published research, it is critical to understand whether peer review is intrinsically susceptible to failure, or whether other extrinsic factors are responsible that distort scientists' decisions. Here we show that even when scientists are motivated to promote the truth, their behaviour may be influenced, and even dominated, by information gleaned from their peers' behaviour, rather than by their personal dispositions. This phenomenon, known as herding, subjects the scientific community to an inherent risk of converging on an incorrect answer and raises the possibility that, under certain conditions, science may not be self-correcting. We further demonstrate that exercising some subjectivity in reviewer decisions, which serves to curb the herding process, can be beneficial for the scientific community in processing available information to estimate truth more accurately. By examining the impact of different models of reviewer decisions on the dynamic process of publication, and thereby on eventual aggregation of knowledge, we provide a new perspective on the ongoing discussion of how the peer-review process may be improved.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Park, In-Uck -- Peacey, Mike W -- Munafo, Marcus R -- MC_UU_12013/6/Medical Research Council/United Kingdom -- Cancer Research UK/United Kingdom -- British Heart Foundation/United Kingdom -- Medical Research Council/United Kingdom -- England -- Nature. 2014 Feb 6;506(7486):93-6. doi: 10.1038/nature12786. Epub 2013 Dec 4.〈br /〉〈span class="detail_caption"〉Author address: 〈/span〉1] Department of Economics, University of Bristol, Bristol BS8 1TN, UK [2] Department of Economics, Sungkyunkwan University, Seoul 110-745, South Korea. ; 1] Department of Economics, University of Bristol, Bristol BS8 1TN, UK [2] Department of Economics, University of Bath, Bath BA2 7AY, UK. ; 1] MRC Integrative Epidemiology Unit (IEU), University of Bristol, Bristol BS8 1BN, UK [2] UK Centre for Tobacco and Alcohol Studies, University of Bristol, Bristol BS8 1TU, UK [3] School of Experimental Psychology, University of Bristol, Bristol BS8 1TU, UK.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/24305052" target="_blank"〉PubMed〈/a〉
    Keywords: *Bias (Epidemiology) ; *Decision Making ; Empirical Research ; Humans ; *Models, Theoretical ; Peer Group ; *Peer Review, Research/standards ; Research Personnel/*psychology/standards
    Print ISSN: 0028-0836
    Electronic ISSN: 1476-4687
    Topics: Biology , Chemistry and Pharmacology , Medicine , Natural Sciences in General , Physics
    Published by Nature Publishing Group (NPG)
    Location Call Number Expected Availability
    BibTip Others were also interested in ...
    PAPER CURRENT
  • 24
    facet.materialart.
    Unknown
    Genetic and molecular basis of drug resistance and species-specific drug action in schistosome parasites (2013)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 2013-11-23
    Description: Oxamniquine resistance evolved in the human blood fluke (Schistosoma mansoni) in Brazil in the 1970s. We crossed parental parasites differing ~500-fold in drug response, determined drug sensitivity and marker segregation in clonally derived second-generation progeny, and identified a single quantitative trait locus (logarithm of odds = 31) on chromosome 6. A sulfotransferase was identified as the causative gene by using RNA interference knockdown and biochemical complementation assays, and we subsequently demonstrated independent origins of loss-of-function mutations in field-derived and laboratory-selected resistant parasites. These results demonstrate the utility of linkage mapping in a human helminth parasite, while crystallographic analyses of protein-drug interactions illuminate the mode of drug action and provide a framework for rational design of oxamniquine derivatives that kill both S. mansoni and S. haematobium, the two species responsible for 〉99% of schistosomiasis cases worldwide.〈br /〉〈br /〉〈a href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4136436/" target="_blank"〉〈img src="https://static.pubmed.gov/portal/portal3rc.fcgi/4089621/img/3977009" border="0"〉〈/a〉   〈a href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4136436/" target="_blank"〉This paper as free author manuscript - peer-reviewed and accepted for publication〈/a〉〈br /〉〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Valentim, Claudia L L -- Cioli, Donato -- Chevalier, Frederic D -- Cao, Xiaohang -- Taylor, Alexander B -- Holloway, Stephen P -- Pica-Mattoccia, Livia -- Guidi, Alessandra -- Basso, Annalisa -- Tsai, Isheng J -- Berriman, Matthew -- Carvalho-Queiroz, Claudia -- Almeida, Marcio -- Aguilar, Hector -- Frantz, Doug E -- Hart, P John -- LoVerde, Philip T -- Anderson, Timothy J C -- 098051/Wellcome Trust/United Kingdom -- 5R21-AI072704/AI/NIAID NIH HHS/ -- 5R21-AI096277/AI/NIAID NIH HHS/ -- C06 RR013556/RR/NCRR NIH HHS/ -- HHSN272201000005I/PHS HHS/ -- R01 AI097576/AI/NIAID NIH HHS/ -- R01-AI097576/AI/NIAID NIH HHS/ -- R21 AI072704/AI/NIAID NIH HHS/ -- R21 AI096277/AI/NIAID NIH HHS/ -- New York, N.Y. -- Science. 2013 Dec 13;342(6164):1385-9. doi: 10.1126/science.1243106. Epub 2013 Nov 21.〈br /〉〈span class="detail_caption"〉Author address: 〈/span〉Departments of Biochemistry and Pathology, University of Texas Health Science Center, San Antonio, TX 78229, USA.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/24263136" target="_blank"〉PubMed〈/a〉
    Keywords: Amino Acid Sequence ; Animals ; Drug Resistance/*genetics ; Gene Knockdown Techniques ; Genetic Linkage ; Helminth Proteins/*genetics ; Humans ; Molecular Sequence Data ; Mutation ; Oxamniquine/*pharmacology ; Phylogeny ; Protein Conformation ; Quantitative Trait Loci ; RNA Interference ; Schistosoma mansoni/*drug effects/*genetics ; Schistosomicides/*pharmacology ; Sulfotransferases/chemistry/classification/*genetics
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
    Published by American Association for the Advancement of Science (AAAS)
    Location Call Number Expected Availability
    BibTip Others were also interested in ...
    PAPER CURRENT
  • 25
    facet.materialart.
    Unknown
    IBI series winner. Engaging high school students in research on smoking behavior (2013)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 2013-07-28
    Description: 〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Munn, Maureen M -- Oura, Hiroki -- Gallivan, Mark -- Van Horne, Katie -- Shouse, Andrew W -- R25 DA013180/DA/NIDA NIH HHS/ -- New York, N.Y. -- Science. 2013 Jul 26;341(6144):360-1. doi: 10.1126/science.1229999.〈br /〉〈span class="detail_caption"〉Author address: 〈/span〉Department of Genome Sciences, University of Washington, Seattle, WA 98195, USA. mmunn@uw.edu〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/23888032" target="_blank"〉PubMed〈/a〉
    Keywords: Awards and Prizes ; *Biomedical Research ; *Curriculum ; *Databases, Factual ; *Epidemiologic Studies ; Humans ; *Smoking/genetics
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
    Published by American Association for the Advancement of Science (AAAS)
    Location Call Number Expected Availability
    BibTip Others were also interested in ...
    PAPER CURRENT
  • 26
    facet.materialart.
    Unknown
    Little emperors: behavioral impacts of China's One-Child Policy (2013)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 2013-01-12
    Description: We document that China's One-Child Policy (OCP), one of the most radical approaches to limiting population growth, has produced significantly less trusting, less trustworthy, more risk-averse, less competitive, more pessimistic, and less conscientious individuals. Our data were collected from economics experiments conducted with 421 individuals born just before and just after the OCP's introduction in 1979. Surveys to elicit personality traits were also used. We used the exogenous imposition of the OCP to identify the causal impact of being an only child, net of family background effects. The OCP thus has significant ramifications for Chinese society.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Cameron, L -- Erkal, N -- Gangadharan, L -- Meng, X -- New York, N.Y. -- Science. 2013 Feb 22;339(6122):953-7. doi: 10.1126/science.1230221. Epub 2013 Jan 10.〈br /〉〈span class="detail_caption"〉Author address: 〈/span〉Department of Econometrics, Monash University, Clayton, Victoria 3800, Australia. lisa.cameron@monash.edu〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/23306438" target="_blank"〉PubMed〈/a〉
    Keywords: Adult ; Altruism ; Anxiety Disorders ; *Attitude ; *Behavior ; China ; Competitive Behavior ; Family ; *Family Planning Policy ; Female ; Games, Experimental ; Humans ; Male ; Only Child/*psychology ; *Personality ; Risk-Taking ; Trust ; Urban Population
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
    Published by American Association for the Advancement of Science (AAAS)
    Location Call Number Expected Availability
    BibTip Others were also interested in ...
    PAPER CURRENT
  • 27
    facet.materialart.
    Unknown
    Outside the pipeline: reimagining science education for nonscientists (2013)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 2013-04-20
    Description: Educational policy increasingly emphasizes knowledge and skills for the preprofessional "science pipeline" rather than helping students use science in daily life. We synthesize research on public engagement with science to develop a research-based plan for cultivating competent outsiders: nonscientists who can access and make sense of science relevant to their lives. Schools should help students access and interpret the science they need in response to specific practical problems, judge the credibility of scientific claims based on both evidence and institutional cues, and cultivate deep amateur involvement in science.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Feinstein, Noah Weeth -- Allen, Sue -- Jenkins, Edgar -- New York, N.Y. -- Science. 2013 Apr 19;340(6130):314-7. doi: 10.1126/science.1230855.〈br /〉〈span class="detail_caption"〉Author address: 〈/span〉Department of Curriculum & Instruction, University of Wisconsin-Madison, 225 North Mills Street, Madison, WI 53706, USA. nfeinstein@wisc.edu〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/23599483" target="_blank"〉PubMed〈/a〉
    Keywords: Education, Professional/*methods ; Humans ; Practice (Psychology) ; *Schools/manpower/organization & administration/standards ; Science/*education ; Thinking
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
    Published by American Association for the Advancement of Science (AAAS)
    Location Call Number Expected Availability
    BibTip Others were also interested in ...
    PAPER CURRENT
  • 28
    facet.materialart.
    Unknown
    Molecular biology. New tool for genome surgery (2013)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 2013-02-16
    Description: 〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉van der Oost, John -- New York, N.Y. -- Science. 2013 Feb 15;339(6121):768-70. doi: 10.1126/science.1234726.〈br /〉〈span class="detail_caption"〉Author address: 〈/span〉Laboratory of Microbiology, Wageningen University, Wageningen, Netherlands. john.vanderoost@wur.nl〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/23413345" target="_blank"〉PubMed〈/a〉
    Keywords: Animals ; Caspase 9/*chemistry ; *DNA Cleavage ; Gene Targeting/*methods ; Genetic Engineering/*methods ; Genome/*genetics ; Genome, Human/*genetics ; Humans ; Inverted Repeat Sequences/*genetics ; Microarray Analysis/*methods ; RNA/*chemistry
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
    Published by American Association for the Advancement of Science (AAAS)
    Location Call Number Expected Availability
    BibTip Others were also interested in ...
    PAPER CURRENT
  • 29
    facet.materialart.
    Unknown
    Call for prudence in whole-genome testing (2013)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 2013-08-31
    Description: 〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉van El, C G -- Dondorp, W J -- de Wert, G M W R -- Cornel, M C -- New York, N.Y. -- Science. 2013 Aug 30;341(6149):958-9. doi: 10.1126/science.341.6149.958-b.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/23990543" target="_blank"〉PubMed〈/a〉
    Keywords: Disease/*genetics ; *Genetic Predisposition to Disease ; Genomics/*ethics/*standards ; Humans ; *Incidental Findings ; *Practice Guidelines as Topic
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
    Published by American Association for the Advancement of Science (AAAS)
    Location Call Number Expected Availability
    BibTip Others were also interested in ...
    PAPER CURRENT
  • 30
    facet.materialart.
    Unknown
    Genetics. A story of swapped ends (2013)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 2013-06-22
    Description: 〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Rowley, Janet D -- New York, N.Y. -- Science. 2013 Jun 21;340(6139):1412-3. doi: 10.1126/science.1241318.〈br /〉〈span class="detail_caption"〉Author address: 〈/span〉Department of Medicine, University of Chicago, 5841 S. Maryland Avenue, Chicago, IL 60637, USA. jrowley@medicine.bsd.uchicago.edu〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/23788787" target="_blank"〉PubMed〈/a〉
    Keywords: Chromosome Banding ; Chromosome Deletion ; Gene Fusion ; Genes, abl ; High-Throughput Nucleotide Sequencing ; History, 20th Century ; Humans ; Leukemia, Myelogenous, Chronic, BCR-ABL Positive/genetics ; Leukemia, Myeloid, Acute/genetics ; Neoplasms/*genetics/history/therapy ; Philadelphia Chromosome ; *Translocation, Genetic
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
    Published by American Association for the Advancement of Science (AAAS)
    Location Call Number Expected Availability
    BibTip Others were also interested in ...
    PAPER CURRENT
  • 31
    facet.materialart.
    Unknown
    Breakthrough of the year 2013. Notable developments (2013)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 2013-12-21
    Description: 〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉New York, N.Y. -- Science. 2013 Dec 20;342(6165):1435-41. doi: 10.1126/science.342.6165.1444.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/24357296" target="_blank"〉PubMed〈/a〉
    Keywords: Animals ; Biological Science Disciplines/history/*trends ; History, 21st Century ; Humans
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
    Published by American Association for the Advancement of Science (AAAS)
    Location Call Number Expected Availability
    BibTip Others were also interested in ...
    PAPER CURRENT
  • 32
    facet.materialart.
    Unknown
    Deciphering the glycosylome of dystroglycanopathies using haploid screens for lassa virus entry (2013)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 2013-03-23
    Description: Glycosylated alpha-dystroglycan (alpha-DG) serves as cellular entry receptor for multiple pathogens, and defects in its glycosylation cause hereditary Walker-Warburg syndrome (WWS). At least eight proteins are critical to glycosylate alpha-DG, but many genes mutated in WWS remain unknown. To identify modifiers of alpha-DG, we performed a haploid screen for Lassa virus entry, a hemorrhagic fever virus causing thousands of deaths annually that hijacks glycosylated alpha-DG to enter cells. In complementary screens, we profiled cells for absence of alpha-DG carbohydrate chains or biochemically related glycans. This revealed virus host factors and a suite of glycosylation units, including all known Walker-Warburg genes and five additional factors critical for the modification of alpha-DG. Our findings accentuate the complexity of this posttranslational feature and point out genes defective in dystroglycanopathies.〈br /〉〈br /〉〈a href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3919138/" target="_blank"〉〈img src="https://static.pubmed.gov/portal/portal3rc.fcgi/4089621/img/3977009" border="0"〉〈/a〉   〈a href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3919138/" target="_blank"〉This paper as free author manuscript - peer-reviewed and accepted for publication〈/a〉〈br /〉〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Jae, Lucas T -- Raaben, Matthijs -- Riemersma, Moniek -- van Beusekom, Ellen -- Blomen, Vincent A -- Velds, Arno -- Kerkhoven, Ron M -- Carette, Jan E -- Topaloglu, Haluk -- Meinecke, Peter -- Wessels, Marja W -- Lefeber, Dirk J -- Whelan, Sean P -- van Bokhoven, Hans -- Brummelkamp, Thijn R -- AI057159/AI/NIAID NIH HHS/ -- AI081842/AI/NIAID NIH HHS/ -- R01 AI081842/AI/NIAID NIH HHS/ -- U54 AI057159/AI/NIAID NIH HHS/ -- New York, N.Y. -- Science. 2013 Apr 26;340(6131):479-83. doi: 10.1126/science.1233675. Epub 2013 Mar 21.〈br /〉〈span class="detail_caption"〉Author address: 〈/span〉Netherlands Cancer Institute, Plesmanlaan 121, Amsterdam, Netherlands.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/23519211" target="_blank"〉PubMed〈/a〉
    Keywords: Amino Acid Sequence ; Cell Line ; Dystroglycans/*metabolism ; Female ; Glycosylation ; Haploidy ; Host-Pathogen Interactions/*genetics ; Humans ; Infant ; Lassa Fever/*genetics/virology ; Lassa virus/*physiology ; Male ; Membrane Proteins/*genetics ; Molecular Sequence Data ; Mutation ; Pedigree ; Proteome/*metabolism ; *Virus Internalization ; Walker-Warburg Syndrome/*genetics
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
    Published by American Association for the Advancement of Science (AAAS)
    Location Call Number Expected Availability
    BibTip Others were also interested in ...
    PAPER CURRENT
  • 33
    facet.materialart.
    Unknown
    Breakthrough of the year 2013. How we did in 2013 and (2013)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 2013-12-21
    Description: 〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉New York, N.Y. -- Science. 2013 Dec 20;342(6165):1442. doi: 10.1126/science.342.6165.1442-b.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/24357294" target="_blank"〉PubMed〈/a〉
    Keywords: Animals ; *Behavior ; Brain/physiology/*ultrastructure ; Electrical Synapses/physiology/ultrastructure ; Humans ; Immunotherapy/*methods ; Mice ; Neoplasms/*therapy ; Sequence Analysis, DNA/*trends ; Single-Cell Analysis/*trends
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
    Published by American Association for the Advancement of Science (AAAS)
    Location Call Number Expected Availability
    BibTip Others were also interested in ...
    PAPER CURRENT
  • 34
    facet.materialart.
    Unknown
    Science education. Driven by diversity (2013)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 2013-04-20
    Description: 〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Ferrini-Mundy, Joan -- New York, N.Y. -- Science. 2013 Apr 19;340(6130):278. doi: 10.1126/science.1235521.〈br /〉〈span class="detail_caption"〉Author address: 〈/span〉National Science Foundation, Arlington, VA 22230, USA. jferrini@nsf.gov〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/23599467" target="_blank"〉PubMed〈/a〉
    Keywords: *Cultural Diversity ; Engineering/*economics ; Ethnic Groups/*education ; Humans ; Mathematics/*education ; Science/*education ; Technology/*education ; United States/ethnology
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
    Published by American Association for the Advancement of Science (AAAS)
    Location Call Number Expected Availability
    BibTip Others were also interested in ...
    PAPER CURRENT
  • 35
    facet.materialart.
    Unknown
    2013 Runners-Up. In vaccine design, looks do matter (2013)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 2013-12-21
    Description: 〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉New York, N.Y. -- Science. 2013 Dec 20;342(6165):1442-3. doi: 10.1126/science.342.6165.1442-a.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/24357293" target="_blank"〉PubMed〈/a〉
    Keywords: Antibodies, Viral/chemistry/immunology ; *Drug Design ; Humans ; Infant ; Protein Conformation ; Protein Engineering ; Respiratory Syncytial Virus Infections/*prevention & control ; Respiratory Syncytial Virus Vaccines/*chemistry/immunology ; Respiratory Syncytial Viruses/*chemistry/immunology ; Viral Fusion Proteins/*chemistry/immunology ; X-Ray Diffraction
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
    Published by American Association for the Advancement of Science (AAAS)
    Location Call Number Expected Availability
    BibTip Others were also interested in ...
    PAPER CURRENT
  • 36
    facet.materialart.
    Unknown
    Interfollicular epidermal stem cells self-renew via autocrine Wnt signaling (2013)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 2013-12-07
    Description: The skin is a classical example of a tissue maintained by stem cells. However, the identity of the stem cells that maintain the interfollicular epidermis and the source of the signals that control their activity remain unclear. Using mouse lineage tracing and quantitative clonal analyses, we showed that the Wnt target gene Axin2 marks interfollicular epidermal stem cells. These Axin2-expressing cells constitute the majority of the basal epidermal layer, compete neutrally, and require Wnt/beta-catenin signaling to proliferate. The same cells contribute robustly to wound healing, with no requirement for a quiescent stem cell subpopulation. By means of double-labeling RNA in situ hybridization in mice, we showed that the Axin2-expressing cells themselves produce Wnt signals as well as long-range secreted Wnt inhibitors, suggesting an autocrine mechanism of stem cell self-renewal.〈br /〉〈br /〉〈a href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4081860/" target="_blank"〉〈img src="https://static.pubmed.gov/portal/portal3rc.fcgi/4089621/img/3977009" border="0"〉〈/a〉   〈a href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4081860/" target="_blank"〉This paper as free author manuscript - peer-reviewed and accepted for publication〈/a〉〈br /〉〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Lim, Xinhong -- Tan, Si Hui -- Koh, Winston Lian Chye -- Chau, Rosanna Man Wah -- Yan, Kelley S -- Kuo, Calvin J -- van Amerongen, Renee -- Klein, Allon Moshe -- Nusse, Roel -- 1R01DK085720/DK/NIDDK NIH HHS/ -- 1U01DK085527/DK/NIDDK NIH HHS/ -- 5K08DK096048/DK/NIDDK NIH HHS/ -- K08 DK096048/DK/NIDDK NIH HHS/ -- P30 DK026743/DK/NIDDK NIH HHS/ -- R01 DK085720/DK/NIDDK NIH HHS/ -- U01 DK085527/DK/NIDDK NIH HHS/ -- Howard Hughes Medical Institute/ -- New York, N.Y. -- Science. 2013 Dec 6;342(6163):1226-30. doi: 10.1126/science.1239730.〈br /〉〈span class="detail_caption"〉Author address: 〈/span〉Department of Developmental Biology, Howard Hughes Medical Institute (HHMI), Institute for Stem Cell Biology and Regenerative Medicine, School of Medicine, Stanford University, Stanford, CA, USA.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/24311688" target="_blank"〉PubMed〈/a〉
    Keywords: Animals ; *Autocrine Communication ; Axin Protein/genetics/metabolism ; Cell Differentiation ; Cell Lineage ; Cell Proliferation ; Cells, Cultured ; Epidermis/*cytology/injuries/metabolism ; Epithelial Cells/cytology/metabolism ; Gene Expression ; Homeostasis ; Humans ; Intercellular Signaling Peptides and Proteins/metabolism ; Keratinocytes/cytology/metabolism ; Mice ; Regeneration ; Skin/injuries ; Stem Cell Niche ; Stem Cells/cytology/*physiology ; Wnt Proteins/metabolism ; *Wnt Signaling Pathway ; Wound Healing ; beta Catenin/genetics/metabolism
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
    Published by American Association for the Advancement of Science (AAAS)
    Location Call Number Expected Availability
    BibTip Others were also interested in ...
    PAPER CURRENT
  • 37
    facet.materialart.
    Unknown
    Microbiology. Eliminating malaria (2013)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 2013-07-03
    Description: 〈br /〉〈br /〉〈a href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4361224/" target="_blank"〉〈img src="https://static.pubmed.gov/portal/portal3rc.fcgi/4089621/img/3977009" border="0"〉〈/a〉   〈a href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4361224/" target="_blank"〉This paper as free author manuscript - peer-reviewed and accepted for publication〈/a〉〈br /〉〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Fidock, David A -- R01 AI050234/AI/NIAID NIH HHS/ -- R01 AI079709/AI/NIAID NIH HHS/ -- New York, N.Y. -- Science. 2013 Jun 28;340(6140):1531-3. doi: 10.1126/science.1240539.〈br /〉〈span class="detail_caption"〉Author address: 〈/span〉Department of Microbiology and Immunology and Division of Infectious Diseases, Columbia University Medical Center, New York, NY 10032, USA. df2260@columbia.edu〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/23812705" target="_blank"〉PubMed〈/a〉
    Keywords: Antimalarials/*administration & dosage ; Artemisinins/*administration & dosage ; Child ; DNA Mismatch Repair/*genetics ; Disease Eradication/*methods ; Drug Resistance/*genetics ; Humans ; Malaria, Falciparum/parasitology/*prevention & control ; Mutation ; Plasmodium falciparum/drug effects/*genetics
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
    Published by American Association for the Advancement of Science (AAAS)
    Location Call Number Expected Availability
    BibTip Others were also interested in ...
    PAPER CURRENT
  • 38
    facet.materialart.
    Unknown
    2013 Runners-Up. Your microbes, your health (2013)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 2013-12-21
    Description: 〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉New York, N.Y. -- Science. 2013 Dec 20;342(6165):1440-1. doi: 10.1126/science.342.6165.1440-b.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/24357292" target="_blank"〉PubMed〈/a〉
    Keywords: Animals ; Anti-Bacterial Agents/administration & dosage ; Fusobacterium/physiology ; Gastrointestinal Tract/*microbiology ; *Health ; Humans ; Infant ; Infant Formula/chemistry ; Kidney/metabolism ; Kidney Calculi/chemically induced/etiology ; Klebsiella/drug effects/metabolism ; Malnutrition/microbiology ; Neoplasms/microbiology ; Rats ; Triazines/metabolism/toxicity
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
    Published by American Association for the Advancement of Science (AAAS)
    Location Call Number Expected Availability
    BibTip Others were also interested in ...
    PAPER CURRENT
  • 39
    facet.materialart.
    Unknown
    Global food supply. Reevaluate pesticides for food security and safety (2013)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 2013-08-21
    Description: 〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Verger, Philippe J P -- Boobis, Alan R -- New York, N.Y. -- Science. 2013 Aug 16;341(6147):717-8. doi: 10.1126/science.1241572.〈br /〉〈span class="detail_caption"〉Author address: 〈/span〉World Health Organization, Geneva, Switzerland. vergerp@who.int〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/23950515" target="_blank"〉PubMed〈/a〉
    Keywords: Animals ; Crops, Agricultural/*chemistry ; Developing Countries ; *Food Safety ; *Food Supply ; Humans ; International Cooperation ; *Pesticide Residues/analysis/toxicity ; *Pesticides/analysis/metabolism/toxicity ; Risk Assessment ; Toxicity Tests
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
    Published by American Association for the Advancement of Science (AAAS)
    Location Call Number Expected Availability
    BibTip Others were also interested in ...
    PAPER CURRENT
  • 40
    facet.materialart.
    Unknown
    Organization of the mitotic chromosome (2013)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 2013-11-10
    Description: Mitotic chromosomes are among the most recognizable structures in the cell, yet for over a century their internal organization remains largely unsolved. We applied chromosome conformation capture methods, 5C and Hi-C, across the cell cycle and revealed two distinct three-dimensional folding states of the human genome. We show that the highly compartmentalized and cell type-specific organization described previously for nonsynchronous cells is restricted to interphase. In metaphase, we identified a homogenous folding state that is locus-independent, common to all chromosomes, and consistent among cell types, suggesting a general principle of metaphase chromosome organization. Using polymer simulations, we found that metaphase Hi-C data are inconsistent with classic hierarchical models and are instead best described by a linearly organized longitudinally compressed array of consecutive chromatin loops.〈br /〉〈br /〉〈a href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4040465/" target="_blank"〉〈img src="https://static.pubmed.gov/portal/portal3rc.fcgi/4089621/img/3977009" border="0"〉〈/a〉   〈a href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4040465/" target="_blank"〉This paper as free author manuscript - peer-reviewed and accepted for publication〈/a〉〈br /〉〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Naumova, Natalia -- Imakaev, Maxim -- Fudenberg, Geoffrey -- Zhan, Ye -- Lajoie, Bryan R -- Mirny, Leonid A -- Dekker, Job -- HG003143/HG/NHGRI NIH HHS/ -- R01 HG003143/HG/NHGRI NIH HHS/ -- U54CA143874/CA/NCI NIH HHS/ -- New York, N.Y. -- Science. 2013 Nov 22;342(6161):948-53. doi: 10.1126/science.1236083. Epub 2013 Nov 7.〈br /〉〈span class="detail_caption"〉Author address: 〈/span〉Program in Systems Biology, Department of Biochemistry and Molecular Pharmacology, University of Massachusetts Medical School (UMMS), 368 Plantation Street, Worcester, MA 01605-0103, USA.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/24200812" target="_blank"〉PubMed〈/a〉
    Keywords: Biopolymers/chemistry ; Cell Cycle/genetics ; Chromatin/chemistry ; Chromosomes, Human, Pair 21/*chemistry ; HeLa Cells ; Humans ; Metaphase/genetics ; Mitosis/*genetics ; Models, Chemical
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
    Published by American Association for the Advancement of Science (AAAS)
    Location Call Number Expected Availability
    BibTip Others were also interested in ...
    PAPER CURRENT
  • 41
    facet.materialart.
    Unknown
    Physiology. Food as a hormone (2013)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 2013-02-23
    Description: 〈br /〉〈br /〉〈a href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4240228/" target="_blank"〉〈img src="https://static.pubmed.gov/portal/portal3rc.fcgi/4089621/img/3977009" border="0"〉〈/a〉   〈a href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4240228/" target="_blank"〉This paper as free author manuscript - peer-reviewed and accepted for publication〈/a〉〈br /〉〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Ryan, Karen K -- Seeley, Randy J -- DK093848/DK/NIDDK NIH HHS/ -- HL111319/HL/NHLBI NIH HHS/ -- K99 HL111319/HL/NHLBI NIH HHS/ -- R01 DK093848/DK/NIDDK NIH HHS/ -- New York, N.Y. -- Science. 2013 Feb 22;339(6122):918-9. doi: 10.1126/science.1234062.〈br /〉〈span class="detail_caption"〉Author address: 〈/span〉Metabolic Diseases Institute, University of Cincinnati, Cincinnati, OH 45237, USA.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/23430646" target="_blank"〉PubMed〈/a〉
    Keywords: Amino Acids, Branched-Chain/metabolism ; Animals ; Bacteria/metabolism ; Diet ; Dietary Carbohydrates/*metabolism ; Dietary Fats/*metabolism ; Digestive System/microbiology ; Fatty Acids/metabolism ; *Food ; *Hormones ; Humans ; Nutritional Physiological Phenomena ; *Signal Transduction
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
    Published by American Association for the Advancement of Science (AAAS)
    Location Call Number Expected Availability
    BibTip Others were also interested in ...
    PAPER CURRENT
  • 42
    facet.materialart.
    Unknown
    Education. Can rating pre-K programs predict children's learning? (2013)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 2013-08-24
    Description: 〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Sabol, T J -- Soliday Hong, S L -- Pianta, R C -- Burchinal, M R -- New York, N.Y. -- Science. 2013 Aug 23;341(6148):845-6. doi: 10.1126/science.1233517.〈br /〉〈span class="detail_caption"〉Author address: 〈/span〉Institute for Policy Research, Northwestern University, Evanston, IL 60208, USA. terri.sabol@northwestern.edu〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/23970684" target="_blank"〉PubMed〈/a〉
    Keywords: Child ; Educational Measurement/*methods ; *Educational Status ; Faculty ; Humans ; Language ; *Learning ; Mathematics/education ; Program Evaluation/*methods ; Reading ; United States
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
    Published by American Association for the Advancement of Science (AAAS)
    Location Call Number Expected Availability
    BibTip Others were also interested in ...
    PAPER CURRENT
  • 43
    facet.materialart.
    Unknown
    2013 Runners-Up. Dishing up mini-organs (2013)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 2013-12-21
    Description: 〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉New York, N.Y. -- Science. 2013 Dec 20;342(6165):1436-7. doi: 10.1126/science.342.6165.1436-b.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/24357288" target="_blank"〉PubMed〈/a〉
    Keywords: Animals ; Brain/anatomy & histology/blood supply/*growth & development ; Humans ; Induced Pluripotent Stem Cells/*cytology ; Neural Stem Cells/*cytology ; *Neurogenesis ; *Organ Culture Techniques
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
    Published by American Association for the Advancement of Science (AAAS)
    Location Call Number Expected Availability
    BibTip Others were also interested in ...
    PAPER CURRENT
  • 44
    facet.materialart.
    Unknown
    2013 Runners-Up. Human cloning at last (2013)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 2013-12-21
    Description: 〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉New York, N.Y. -- Science. 2013 Dec 20;342(6165):1436. doi: 10.1126/science.342.6165.1436-a.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/24357287" target="_blank"〉PubMed〈/a〉
    Keywords: Animals ; Cell Line ; Cell Separation ; Cloning, Organism/*methods ; Female ; Humans ; *Induced Pluripotent Stem Cells ; Nuclear Transfer Techniques ; Pregnancy ; *Research Embryo Creation ; Surrogate Mothers
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
    Published by American Association for the Advancement of Science (AAAS)
    Location Call Number Expected Availability
    BibTip Others were also interested in ...
    PAPER CURRENT
  • 45
    facet.materialart.
    Unknown
    27-Hydroxycholesterol links hypercholesterolemia and breast cancer pathophysiology (2013)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 2013-11-30
    Description: Hypercholesterolemia is a risk factor for estrogen receptor (ER)-positive breast cancers and is associated with a decreased response of tumors to endocrine therapies. Here, we show that 27-hydroxycholesterol (27HC), a primary metabolite of cholesterol and an ER and liver X receptor (LXR) ligand, increases ER-dependent growth and LXR-dependent metastasis in mouse models of breast cancer. The effects of cholesterol on tumor pathology required its conversion to 27HC by the cytochrome P450 oxidase CYP27A1 and were attenuated by treatment with CYP27A1 inhibitors. In human breast cancer specimens, CYP27A1 expression levels correlated with tumor grade. In high-grade tumors, both tumor cells and tumor-associated macrophages exhibited high expression levels of the enzyme. Thus, lowering circulating cholesterol levels or interfering with its conversion to 27HC may be a useful strategy to prevent and/or treat breast cancer.〈br /〉〈br /〉〈a href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3899689/" target="_blank"〉〈img src="https://static.pubmed.gov/portal/portal3rc.fcgi/4089621/img/3977009" border="0"〉〈/a〉   〈a href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3899689/" target="_blank"〉This paper as free author manuscript - peer-reviewed and accepted for publication〈/a〉〈br /〉〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Nelson, Erik R -- Wardell, Suzanne E -- Jasper, Jeff S -- Park, Sunghee -- Suchindran, Sunil -- Howe, Matthew K -- Carver, Nicole J -- Pillai, Ruchita V -- Sullivan, Patrick M -- Sondhi, Varun -- Umetani, Michihisa -- Geradts, Joseph -- McDonnell, Donald P -- K99CA172357/CA/NCI NIH HHS/ -- R37 DK048807/DK/NIDDK NIH HHS/ -- R37DK048807/DK/NIDDK NIH HHS/ -- T32 CA059365/CA/NCI NIH HHS/ -- New York, N.Y. -- Science. 2013 Nov 29;342(6162):1094-8. doi: 10.1126/science.1241908.〈br /〉〈span class="detail_caption"〉Author address: 〈/span〉Department of Pharmacology and Cancer Biology, Duke University School of Medicine, Durham, NC 27710, USA.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/24288332" target="_blank"〉PubMed〈/a〉
    Keywords: Animals ; Breast Neoplasms/blood/*metabolism/*pathology ; Cell Line, Tumor ; Cholestanetriol 26-Monooxygenase/antagonists & inhibitors/metabolism ; Disease Models, Animal ; Female ; Humans ; Hydroxycholesterols/antagonists & inhibitors/blood/*metabolism ; Hypercholesterolemia/blood/*metabolism ; Lung Neoplasms/secondary ; Mice ; Tumor Cells, Cultured
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
    Published by American Association for the Advancement of Science (AAAS)
    Location Call Number Expected Availability
    BibTip Others were also interested in ...
    PAPER CURRENT
  • 46
    facet.materialart.
    Unknown
    Evolution. Culture, genes, and the human revolution (2013)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 2013-05-25
    Description: 〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Fisher, Simon E -- Ridley, Matt -- New York, N.Y. -- Science. 2013 May 24;340(6135):929-30. doi: 10.1126/science.1236171.〈br /〉〈span class="detail_caption"〉Author address: 〈/span〉Department of Language and Genetics, Max Planck Institute for Psycholinguistics, Nijmegen, Netherlands. imon.fi sher@mpi.nl〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/23704558" target="_blank"〉PubMed〈/a〉
    Keywords: *Culture ; *Evolution, Molecular ; Forkhead Transcription Factors/*genetics ; Humans
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
    Published by American Association for the Advancement of Science (AAAS)
    Location Call Number Expected Availability
    BibTip Others were also interested in ...
    PAPER CURRENT
  • 47
    facet.materialart.
    Unknown
    2013 Runners-Up. CLARITY makes it perfectly clear (2013)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 2013-12-21
    Description: 〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉New York, N.Y. -- Science. 2013 Dec 20;342(6165):1434-5. doi: 10.1126/science.342.6165.1434-b.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/24357286" target="_blank"〉PubMed〈/a〉
    Keywords: Animals ; Brain/*ultrastructure ; Cell Count/methods ; Cell Membrane/chemistry ; Humans ; Imaging, Three-Dimensional/*methods ; Membrane Lipids/*chemistry ; Mice ; Neurons/chemistry/*ultrastructure ; Staining and Labeling/*methods
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
    Published by American Association for the Advancement of Science (AAAS)
    Location Call Number Expected Availability
    BibTip Others were also interested in ...
    PAPER CURRENT
  • 48
    facet.materialart.
    Unknown
    2013 Runners-Up. Genetic microsurgery for the masses (2013)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 2013-12-21
    Description: 〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉New York, N.Y. -- Science. 2013 Dec 20;342(6165):1434-5. doi: 10.1126/science.342.6165.1434-a.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/24357285" target="_blank"〉PubMed〈/a〉
    Keywords: Animals ; Bacterial Proteins/genetics/metabolism ; Clustered Regularly Interspaced Short Palindromic Repeats/*genetics ; DNA/genetics ; Genetic Diseases, Inborn/*surgery ; Genetic Therapy/*methods ; Humans ; Mice ; Microsurgery/*methods ; *RNA Editing ; RNA, Guide/genetics/metabolism ; Rats
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
    Published by American Association for the Advancement of Science (AAAS)
    Location Call Number Expected Availability
    BibTip Others were also interested in ...
    PAPER CURRENT
  • 49
    facet.materialart.
    Unknown
    Understanding neurocognitive developmental disorders can improve education for all (2013)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 2013-04-20
    Description: Specific learning disabilities (SLDs) are estimated to affect up to 10% of the population, and they co-occur far more often than would be expected, given their prevalences. We need to understand the complex etiology of SLDs and their co-occurrences in order to underpin the training of teachers, school psychologists, and clinicians, so that they can reliably recognize SLDs and optimize the learning contexts for individual learners.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Butterworth, Brian -- Kovas, Yulia -- New York, N.Y. -- Science. 2013 Apr 19;340(6130):300-5. doi: 10.1126/science.1231022.〈br /〉〈span class="detail_caption"〉Author address: 〈/span〉Institute of Cognitive Neuroscience, University College London, Alexandra House, 17 Queen Square, London WC1N 3AR, UK. b.butterworth@ucl.ac.uk〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/23599478" target="_blank"〉PubMed〈/a〉
    Keywords: Attention Deficit Disorder with ; Hyperactivity/diagnosis/physiopathology/psychology ; Child ; Child, Preschool ; Cognition Disorders/*diagnosis/epidemiology/*etiology/genetics ; Education, Medical/methods ; Education, Special/methods ; Faculty ; Humans ; Learning ; Learning Disorders/*diagnosis/epidemiology/*etiology/genetics ; Nerve Net/*abnormalities/growth & development ; Physicians ; Prevalence ; Psychology/education ; Teaching/*methods
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
    Published by American Association for the Advancement of Science (AAAS)
    Location Call Number Expected Availability
    BibTip Others were also interested in ...
    PAPER CURRENT
  • 50
    facet.materialart.
    Unknown
    Inflammation. Inflammation's yin-yang. Introduction (2013)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 2013-01-12
    Description: 〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Mueller, Kristen -- New York, N.Y. -- Science. 2013 Jan 11;339(6116):155. doi: 10.1126/science.339.6116.155.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/23307731" target="_blank"〉PubMed〈/a〉
    Keywords: *Cardiovascular Diseases/physiopathology ; Humans ; *Immune System/physiology/physiopathology ; *Inflammation/immunology/physiopathology ; *Metabolic Syndrome X/physiopathology ; *Neurodegenerative Diseases/physiopathology
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
    Published by American Association for the Advancement of Science (AAAS)
    Location Call Number Expected Availability
    BibTip Others were also interested in ...
    PAPER CURRENT
  • 51
    facet.materialart.
    Unknown
    Morals and markets (2013)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 2013-05-11
    Description: The possibility that market interaction may erode moral values is a long-standing, but controversial, hypothesis in the social sciences, ethics, and philosophy. To date, empirical evidence on decay of moral values through market interaction has been scarce. We present controlled experimental evidence on how market interaction changes how human subjects value harm and damage done to third parties. In the experiment, subjects decide between either saving the life of a mouse or receiving money. We compare individual decisions to those made in a bilateral and a multilateral market. In both markets, the willingness to kill the mouse is substantially higher than in individual decisions. Furthermore, in the multilateral market, prices for life deteriorate tremendously. In contrast, for morally neutral consumption choices, differences between institutions are small.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Falk, Armin -- Szech, Nora -- New York, N.Y. -- Science. 2013 May 10;340(6133):707-11. doi: 10.1126/science.1231566.〈br /〉〈span class="detail_caption"〉Author address: 〈/span〉Center for Economics and Neuroscience, University of Bonn, Bonn, Germany. armin.falk@uni-bonn.de〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/23661753" target="_blank"〉PubMed〈/a〉
    Keywords: Animals ; Commerce/*ethics ; Decision Making ; Humans ; Mice ; *Morals
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
    Published by American Association for the Advancement of Science (AAAS)
    Location Call Number Expected Availability
    BibTip Others were also interested in ...
    PAPER CURRENT
  • 52
    facet.materialart.
    Unknown
    Antibodies. The future is now. Introduction (2013)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 2013-09-14
    Description: 〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Mueller, Kristen L -- New York, N.Y. -- Science. 2013 Sep 13;341(6151):1191. doi: 10.1126/science.341.6151.1191.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/24031010" target="_blank"〉PubMed〈/a〉
    Keywords: Antibodies, Monoclonal/immunology/*therapeutic use ; Communicable Diseases/*therapy ; Humans ; Molecular Targeted Therapy/*trends ; Neoplasms/*therapy ; Vaccines/immunology/therapeutic use
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
    Published by American Association for the Advancement of Science (AAAS)
    Location Call Number Expected Availability
    BibTip Others were also interested in ...
    PAPER CURRENT
  • 53
    facet.materialart.
    Unknown
    Mg2+ regulates cytotoxic functions of NK and CD8 T cells in chronic EBV infection through NKG2D (2013)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 2013-07-13
    Description: The magnesium transporter 1 (MAGT1) is a critical regulator of basal intracellular free magnesium (Mg(2+)) concentrations. Individuals with genetic deficiencies in MAGT1 have high levels of Epstein-Barr virus (EBV) and a predisposition to lymphoma. We show that decreased intracellular free Mg(2+) causes defective expression of the natural killer activating receptor NKG2D in natural killer (NK) and CD8(+) T cells and impairs cytolytic responses against EBV. Notably, magnesium supplementation in MAGT1-deficient patients restores intracellular free Mg(2+) and NKG2D while concurrently reducing EBV-infected cells in vivo, demonstrating a link between NKG2D cytolytic activity and EBV antiviral immunity in humans. Moreover, these findings reveal a specific molecular function of free basal intracellular Mg(2+) in eukaryotic cells.〈br /〉〈br /〉〈a href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3894782/" target="_blank"〉〈img src="https://static.pubmed.gov/portal/portal3rc.fcgi/4089621/img/3977009" border="0"〉〈/a〉   〈a href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3894782/" target="_blank"〉This paper as free author manuscript - peer-reviewed and accepted for publication〈/a〉〈br /〉〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Chaigne-Delalande, Benjamin -- Li, Feng-Yen -- O'Connor, Geraldine M -- Lukacs, Marshall J -- Jiang, Ping -- Zheng, Lixin -- Shatzer, Amber -- Biancalana, Matthew -- Pittaluga, Stefania -- Matthews, Helen F -- Jancel, Timothy J -- Bleesing, Jack J -- Marsh, Rebecca A -- Kuijpers, Taco W -- Nichols, Kim E -- Lucas, Carrie L -- Nagpal, Sunil -- Mehmet, Huseyin -- Su, Helen C -- Cohen, Jeffrey I -- Uzel, Gulbu -- Lenardo, Michael J -- T32 GM007618/GM/NIGMS NIH HHS/ -- ZIA AI001187-01/Intramural NIH HHS/ -- New York, N.Y. -- Science. 2013 Jul 12;341(6142):186-91. doi: 10.1126/science.1240094.〈br /〉〈span class="detail_caption"〉Author address: 〈/span〉Molecular Development of the Immune System Section, Lymphocyte Molecular Genetics Unit, Laboratory of Immunology, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD 20892, USA.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/23846901" target="_blank"〉PubMed〈/a〉
    Keywords: CD8-Positive T-Lymphocytes/*immunology ; Cation Transport Proteins/genetics/metabolism ; *Cytotoxicity, Immunologic ; Epstein-Barr Virus Infections/*immunology ; Humans ; Killer Cells, Natural/*immunology ; Magnesium/*immunology ; Magnesium Deficiency/*immunology ; NK Cell Lectin-Like Receptor Subfamily K/genetics/*metabolism ; X-Linked Combined Immunodeficiency Diseases/immunology
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
    Published by American Association for the Advancement of Science (AAAS)
    Location Call Number Expected Availability
    BibTip Others were also interested in ...
    PAPER CURRENT
  • 54
    facet.materialart.
    Unknown
    Allele-specific silencing of mutant Myh6 transcripts in mice suppresses hypertrophic cardiomyopathy (2013)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 2013-10-05
    Description: Dominant mutations in sarcomere proteins such as the myosin heavy chains (MHC) are the leading genetic causes of human hypertrophic cardiomyopathy (HCM) and dilated cardiomyopathy. We found that expression of the HCM-causing cardiac MHC gene (Myh6) R403Q mutation in mice can be selectively silenced by an RNA interference (RNAi) cassette delivered by an adeno-associated virus vector. RNAi-transduced MHC(403/+) mice developed neither hypertrophy nor myocardial fibrosis, the pathologic manifestations of HCM, for at least 6 months. Because inhibition of HCM was achieved by only a 25% reduction in the levels of the mutant transcripts, we suggest that the variable clinical phenotype in HCM patients reflects allele-specific expression and that partial silencing of mutant transcripts may have therapeutic benefit.〈br /〉〈br /〉〈a href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4100553/" target="_blank"〉〈img src="https://static.pubmed.gov/portal/portal3rc.fcgi/4089621/img/3977009" border="0"〉〈/a〉   〈a href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4100553/" target="_blank"〉This paper as free author manuscript - peer-reviewed and accepted for publication〈/a〉〈br /〉〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Jiang, Jianming -- Wakimoto, Hiroko -- Seidman, J G -- Seidman, Christine E -- R01 HL084553/HL/NHLBI NIH HHS/ -- R01HL084553/HL/NHLBI NIH HHS/ -- U01 HL066582/HL/NHLBI NIH HHS/ -- U01 HL098166/HL/NHLBI NIH HHS/ -- U01HL098166/HL/NHLBI NIH HHS/ -- Howard Hughes Medical Institute/ -- New York, N.Y. -- Science. 2013 Oct 4;342(6154):111-4. doi: 10.1126/science.1236921.〈br /〉〈span class="detail_caption"〉Author address: 〈/span〉Department of Genetics, Harvard Medical School, Boston, MA 02115, USA.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/24092743" target="_blank"〉PubMed〈/a〉
    Keywords: Alleles ; Animals ; Cardiomyopathy, Hypertrophic/*diagnosis/genetics/pathology ; Dependovirus ; Fibrosis ; Gene Silencing ; *Genetic Therapy ; HEK293 Cells ; Humans ; Mice ; Mutation ; Myosin Heavy Chains/*genetics ; *RNA Interference
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
    Published by American Association for the Advancement of Science (AAAS)
    Location Call Number Expected Availability
    BibTip Others were also interested in ...
    PAPER CURRENT
  • 55
    facet.materialart.
    Unknown
    Controversial salt report peppered with uncertainty (2013)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 2013-09-07
    Description: 〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Johns, David Merritt -- Bayer, Ronald -- Galea, Sandro -- New York, N.Y. -- Science. 2013 Sep 6;341(6150):1063-4. doi: 10.1126/science.341.6150.1063.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/24009376" target="_blank"〉PubMed〈/a〉
    Keywords: Cardiovascular Diseases/*epidemiology ; Diet, Sodium-Restricted/*standards ; *Health Planning Guidelines ; Humans
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
    Published by American Association for the Advancement of Science (AAAS)
    Location Call Number Expected Availability
    BibTip Others were also interested in ...
    PAPER CURRENT
  • 56
    facet.materialart.
    Unknown
    Infographic: pesticide planet (2013)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 2013-08-21
    Description: 〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉New York, N.Y. -- Science. 2013 Aug 16;341(6147):730-1. doi: 10.1126/science.341.6147.730.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/23950524" target="_blank"〉PubMed〈/a〉
    Keywords: Animals ; Crops, Agricultural ; Developing Countries ; Humans ; Malaria/prevention & control ; *Pest Control/methods/statistics & numerical data ; *Pesticides/poisoning/toxicity ; Plant Weeds
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
    Published by American Association for the Advancement of Science (AAAS)
    Location Call Number Expected Availability
    BibTip Others were also interested in ...
    PAPER CURRENT
  • 57
    facet.materialart.
    Unknown
    A cancer to-do list (2013)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 2013-10-26
    Description: 〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉New York, N.Y. -- Science. 2013 Oct 25;342(6157):418. doi: 10.1126/science.342.6157.418.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/24159026" target="_blank"〉PubMed〈/a〉
    Keywords: Developing Countries ; Humans ; National Cancer Institute (U.S.)/*economics ; Neoplasms/*economics/*epidemiology ; Obesity/epidemiology ; Registries ; Risk ; United States
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
    Published by American Association for the Advancement of Science (AAAS)
    Location Call Number Expected Availability
    BibTip Others were also interested in ...
    PAPER CURRENT
  • 58
    facet.materialart.
    Unknown
    IBI* series winner. Radiation and atomic literacy for nonscientists (2013)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 2013-10-26
    Description: 〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Johnson, Andy -- New York, N.Y. -- Science. 2013 Oct 25;342(6157):436-7. doi: 10.1126/science.1230003.〈br /〉〈span class="detail_caption"〉Author address: 〈/span〉Center for Advancement of Math and Science Education (CAMSE), Black Hills State University, 1200 University Street, Spearfish, SD 57799, USA.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/24159038" target="_blank"〉PubMed〈/a〉
    Keywords: Humans ; Nuclear Physics/*education ; *Radiation, Ionizing ; *Radioactivity ; Teaching Materials
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
    Published by American Association for the Advancement of Science (AAAS)
    Location Call Number Expected Availability
    BibTip Others were also interested in ...
    PAPER CURRENT
  • 59
    facet.materialart.
    Unknown
    Newsmaker interview: Geoffrey Ling. DARPA aims to rebuild brains. Interview by Emily Underwood (2013)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 2013-11-30
    Description: 〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Ling, Geoffrey -- New York, N.Y. -- Science. 2013 Nov 29;342(6162):1029-30. doi: 10.1126/science.342.6162.1029.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/24288309" target="_blank"〉PubMed〈/a〉
    Keywords: Biomedical Research/economics ; Brain/*physiology ; Brain Injuries/*complications ; Capital Financing ; Deep Brain Stimulation ; Humans ; *Memory ; Memory Disorders/etiology/*therapy ; *Military Personnel
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
    Published by American Association for the Advancement of Science (AAAS)
    Location Call Number Expected Availability
    BibTip Others were also interested in ...
    PAPER CURRENT
  • 60
    facet.materialart.
    Unknown
    In defense of physician-investor collaboration (2013)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 2013-02-16
    Description: 〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Chakma, Justin -- New York, N.Y. -- Science. 2013 Feb 15;339(6121):756-7. doi: 10.1126/science.339.6121.756-b.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/23413335" target="_blank"〉PubMed〈/a〉
    Keywords: *Conflict of Interest ; *Consultants ; *Disclosure ; Humans ; *Investments ; *Research Personnel
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
    Published by American Association for the Advancement of Science (AAAS)
    Location Call Number Expected Availability
    BibTip Others were also interested in ...
    PAPER CURRENT
  • 61
    facet.materialart.
    Unknown
    Global epigenomic reconfiguration during mammalian brain development (2013)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 2013-07-06
    Description: DNA methylation is implicated in mammalian brain development and plasticity underlying learning and memory. We report the genome-wide composition, patterning, cell specificity, and dynamics of DNA methylation at single-base resolution in human and mouse frontal cortex throughout their lifespan. Widespread methylome reconfiguration occurs during fetal to young adult development, coincident with synaptogenesis. During this period, highly conserved non-CG methylation (mCH) accumulates in neurons, but not glia, to become the dominant form of methylation in the human neuronal genome. Moreover, we found an mCH signature that identifies genes escaping X-chromosome inactivation. Last, whole-genome single-base resolution 5-hydroxymethylcytosine (hmC) maps revealed that hmC marks fetal brain cell genomes at putative regulatory regions that are CG-demethylated and activated in the adult brain and that CG demethylation at these hmC-poised loci depends on Tet2 activity.〈br /〉〈br /〉〈a href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3785061/" target="_blank"〉〈img src="https://static.pubmed.gov/portal/portal3rc.fcgi/4089621/img/3977009" border="0"〉〈/a〉   〈a href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3785061/" target="_blank"〉This paper as free author manuscript - peer-reviewed and accepted for publication〈/a〉〈br /〉〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Lister, Ryan -- Mukamel, Eran A -- Nery, Joseph R -- Urich, Mark -- Puddifoot, Clare A -- Johnson, Nicholas D -- Lucero, Jacinta -- Huang, Yun -- Dwork, Andrew J -- Schultz, Matthew D -- Yu, Miao -- Tonti-Filippini, Julian -- Heyn, Holger -- Hu, Shijun -- Wu, Joseph C -- Rao, Anjana -- Esteller, Manel -- He, Chuan -- Haghighi, Fatemeh G -- Sejnowski, Terrence J -- Behrens, M Margarita -- Ecker, Joseph R -- AI44432/AI/NIAID NIH HHS/ -- CA151535/CA/NCI NIH HHS/ -- HD065812/HD/NICHD NIH HHS/ -- HG006827/HG/NHGRI NIH HHS/ -- K99NS080911/NS/NINDS NIH HHS/ -- MH094670/MH/NIMH NIH HHS/ -- R01 AI044432/AI/NIAID NIH HHS/ -- R01 CA151535/CA/NCI NIH HHS/ -- R01 HD065812/HD/NICHD NIH HHS/ -- R01 HG006827/HG/NHGRI NIH HHS/ -- R01 MH094670/MH/NIMH NIH HHS/ -- R01 MH094774/MH/NIMH NIH HHS/ -- Howard Hughes Medical Institute/ -- New York, N.Y. -- Science. 2013 Aug 9;341(6146):1237905. doi: 10.1126/science.1237905. Epub 2013 Jul 4.〈br /〉〈span class="detail_caption"〉Author address: 〈/span〉Genomic Analysis Laboratory, The Salk Institute for Biological Studies, La Jolla, CA 92037, USA. ryan.lister@uwa.edu.au〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/23828890" target="_blank"〉PubMed〈/a〉
    Keywords: 5-Methylcytosine/metabolism ; Adult ; Animals ; Base Sequence ; Conserved Sequence ; Cytosine/*analogs & derivatives/metabolism ; *DNA Methylation ; *Epigenesis, Genetic ; Epigenomics ; Frontal Lobe/*growth & development ; *Gene Expression Regulation, Developmental ; Genome-Wide Association Study ; Humans ; Longevity ; Mice ; Mice, Inbred C57BL ; X Chromosome Inactivation/genetics
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
    Published by American Association for the Advancement of Science (AAAS)
    Location Call Number Expected Availability
    BibTip Others were also interested in ...
    PAPER CURRENT
  • 62
    facet.materialart.
    Unknown
    Avian influenza. Critics skeptical as flu scientists argue for controversial H7N9 studies (2013)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 2013-08-09
    Description: 〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Malakoff, David -- New York, N.Y. -- Science. 2013 Aug 9;341(6146):601.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/23926188" target="_blank"〉PubMed〈/a〉
    Keywords: Animals ; Drug Resistance, Multiple, Viral/*genetics ; Humans ; Influenza A virus/*genetics/*pathogenicity ; Influenza in Birds/*transmission/*virology ; Influenza, Human/*prevention & control ; Pandemics/*prevention & control
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
    Published by American Association for the Advancement of Science (AAAS)
    Location Call Number Expected Availability
    BibTip Others were also interested in ...
    PAPER CURRENT
  • 63
    facet.materialart.
    Unknown
    Influence of HLA-C expression level on HIV control (2013)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 2013-04-06
    Description: A variant upstream of human leukocyte antigen C (HLA-C) shows the most significant genome-wide effect on HIV control in European Americans and is also associated with the level of HLA-C expression. We characterized the differential cell surface expression levels of all common HLA-C allotypes and tested directly for effects of HLA-C expression on outcomes of HIV infection in 5243 individuals. Increasing HLA-C expression was associated with protection against multiple outcomes independently of individual HLA allelic effects in both African and European Americans, regardless of their distinct HLA-C frequencies and linkage relationships with HLA-B and HLA-A. Higher HLA-C expression was correlated with increased likelihood of cytotoxic T lymphocyte responses and frequency of viral escape mutation. In contrast, high HLA-C expression had a deleterious effect in Crohn's disease, suggesting a broader influence of HLA expression levels in human disease.〈br /〉〈br /〉〈a href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3784322/" target="_blank"〉〈img src="https://static.pubmed.gov/portal/portal3rc.fcgi/4089621/img/3977009" border="0"〉〈/a〉   〈a href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3784322/" target="_blank"〉This paper as free author manuscript - peer-reviewed and accepted for publication〈/a〉〈br /〉〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Apps, Richard -- Qi, Ying -- Carlson, Jonathan M -- Chen, Haoyan -- Gao, Xiaojiang -- Thomas, Rasmi -- Yuki, Yuko -- Del Prete, Greg Q -- Goulder, Philip -- Brumme, Zabrina L -- Brumme, Chanson J -- John, Mina -- Mallal, Simon -- Nelson, George -- Bosch, Ronald -- Heckerman, David -- Stein, Judy L -- Soderberg, Kelly A -- Moody, M Anthony -- Denny, Thomas N -- Zeng, Xue -- Fang, Jingyuan -- Moffett, Ashley -- Lifson, Jeffrey D -- Goedert, James J -- Buchbinder, Susan -- Kirk, Gregory D -- Fellay, Jacques -- McLaren, Paul -- Deeks, Steven G -- Pereyra, Florencia -- Walker, Bruce -- Michael, Nelson L -- Weintrob, Amy -- Wolinsky, Steven -- Liao, Wilson -- Carrington, Mary -- 5-M01-RR-00722/RR/NCRR NIH HHS/ -- HHSN261200800001E/CA/NCI NIH HHS/ -- HHSN261200800001E/PHS HHS/ -- K08 AR057763/AR/NIAMS NIH HHS/ -- K08AR057763/AR/NIAMS NIH HHS/ -- K24 AI069994/AI/NIAID NIH HHS/ -- K24AI069994/AI/NIAID NIH HHS/ -- N02-CP-55504/CP/NCI NIH HHS/ -- P30 AI027763/AI/NIAID NIH HHS/ -- P30 AI027767/AI/NIAID NIH HHS/ -- P30 AI027767-24/AI/NIAID NIH HHS/ -- P30 MH62246/MH/NIMH NIH HHS/ -- PG/09/077/27964/British Heart Foundation/United Kingdom -- R01 AI046995/AI/NIAID NIH HHS/ -- R01 AI060460/AI/NIAID NIH HHS/ -- R01 AI087145/AI/NIAID NIH HHS/ -- R01 AR065174/AR/NIAMS NIH HHS/ -- R01-AI046995/AI/NIAID NIH HHS/ -- R01-AI060460/AI/NIAID NIH HHS/ -- R01-DA-04334/DA/NIDA NIH HHS/ -- R01-DA-12568/DA/NIDA NIH HHS/ -- R01-DA04334/DA/NIDA NIH HHS/ -- R01-DA12568/DA/NIDA NIH HHS/ -- R24 AI067039/AI/NIAID NIH HHS/ -- U01-AI-067854/AI/NIAID NIH HHS/ -- U01-AI-35039/AI/NIAID NIH HHS/ -- U01-AI-35040/AI/NIAID NIH HHS/ -- U01-AI-35041/AI/NIAID NIH HHS/ -- U01-AI-35042/AI/NIAID NIH HHS/ -- U01-AI-35043/AI/NIAID NIH HHS/ -- U01-AI-37613/AI/NIAID NIH HHS/ -- U01-AI-37984/AI/NIAID NIH HHS/ -- UL1 RR024131/RR/NCRR NIH HHS/ -- Wellcome Trust/United Kingdom -- New York, N.Y. -- Science. 2013 Apr 5;340(6128):87-91. doi: 10.1126/science.1232685.〈br /〉〈span class="detail_caption"〉Author address: 〈/span〉Cancer and Inflammation Program, Laboratory of Experimental Immunology, Science Applications International Corporation-Frederick, Inc., Frederick National Laboratory for Cancer Research, Frederick, MD 21702, USA.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/23559252" target="_blank"〉PubMed〈/a〉
    Keywords: African Americans/genetics ; Alleles ; Amino Acid Sequence ; Anti-Retroviral Agents/therapeutic use ; Crohn Disease/genetics/immunology ; *Gene Expression Regulation ; HIV/genetics/*immunology ; HIV Infections/drug therapy/*genetics/*immunology ; HLA-C Antigens/*genetics ; Humans ; Immunodominant Epitopes/genetics ; Molecular Sequence Data ; Mutation ; Peptide Fragments/immunology ; Polymorphism, Single Nucleotide ; T-Lymphocytes, Cytotoxic/*immunology ; Viral Load/genetics
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
    Published by American Association for the Advancement of Science (AAAS)
    Location Call Number Expected Availability
    BibTip Others were also interested in ...
    PAPER CURRENT
  • 64
    facet.materialart.
    Unknown
    Bioinformatics. Top contenders blast Pentagon's new bioterror detection prize (2013)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 2013-08-03
    Description: 〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Servick, Kelly -- New York, N.Y. -- Science. 2013 Aug 2;341(6145):449. doi: 10.1126/science.341.6145.449.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/23908200" target="_blank"〉PubMed〈/a〉
    Keywords: *Awards and Prizes ; *Bioterrorism ; Computational Biology ; Humans ; Sequence Analysis, DNA/*methods
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
    Published by American Association for the Advancement of Science (AAAS)
    Location Call Number Expected Availability
    BibTip Others were also interested in ...
    PAPER CURRENT
  • 65
    facet.materialart.
    Unknown
    Health information and the like--response (2013)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 2013-12-18
    Description: 〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Aral, Sinan -- Muchnik, Lev -- Taylor, Sean -- New York, N.Y. -- Science. 2013 Dec 13;342(6164):1315-6. doi: 10.1126/science.342.6164.1315-b.〈br /〉〈span class="detail_caption"〉Author address: 〈/span〉MIT Sloan School of Management, Cambridge, MA 02142, USA.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/24337275" target="_blank"〉PubMed〈/a〉
    Keywords: *Behavior Control ; *Decision Making ; Humans ; *Politics ; *Public Opinion ; *Social Environment
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
    Published by American Association for the Advancement of Science (AAAS)
    Location Call Number Expected Availability
    BibTip Others were also interested in ...
    PAPER CURRENT
  • 66
    facet.materialart.
    Unknown
    Human Evolution. Elusive Denisovans sighted in oldest human DNA (2013)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 2013-12-07
    Description: 〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Gibbons, Ann -- New York, N.Y. -- Science. 2013 Dec 6;342(6163):1156. doi: 10.1126/science.342.6163.1156.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/24311652" target="_blank"〉PubMed〈/a〉
    Keywords: Animals ; *Biological Evolution ; Bone and Bones ; *DNA, Mitochondrial ; *Fossils ; *Hominidae ; Humans ; Neanderthals ; Spain
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
    Published by American Association for the Advancement of Science (AAAS)
    Location Call Number Expected Availability
    BibTip Others were also interested in ...
    PAPER CURRENT
  • 67
    facet.materialart.
    Unknown
    Real-time dynamics of RNA polymerase II clustering in live human cells (2013)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 2013-07-06
    Description: Transcription is reported to be spatially compartmentalized in nuclear transcription factories with clusters of RNA polymerase II (Pol II). However, little is known about when these foci assemble or their relative stability. We developed a quantitative single-cell approach to characterize protein spatiotemporal organization, with single-molecule sensitivity in live eukaryotic cells. We observed that Pol II clusters form transiently, with an average lifetime of 5.1 (+/- 0.4) seconds, which refutes the notion that they are statically assembled substructures. Stimuli affecting transcription yielded orders-of-magnitude changes in the dynamics of Pol II clusters, which implies that clustering is regulated and plays a role in the cell's ability to effect rapid response to external signals. Our results suggest that transient crowding of enzymes may aid in rate-limiting steps of gene regulation.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Cisse, Ibrahim I -- Izeddin, Ignacio -- Causse, Sebastien Z -- Boudarene, Lydia -- Senecal, Adrien -- Muresan, Leila -- Dugast-Darzacq, Claire -- Hajj, Bassam -- Dahan, Maxime -- Darzacq, Xavier -- New York, N.Y. -- Science. 2013 Aug 9;341(6146):664-7. doi: 10.1126/science.1239053. Epub 2013 Jul 4.〈br /〉〈span class="detail_caption"〉Author address: 〈/span〉Functional Imaging of Transcription, CNRS UMR8197, Ecole Normale Superieure, Institut de Biologie de l'ENS, IBENS, Paris, 75005 France.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/23828889" target="_blank"〉PubMed〈/a〉
    Keywords: Cell Line, Tumor ; Flavonoids/pharmacology ; *Gene Expression Regulation ; Humans ; Piperidines/pharmacology ; RNA Polymerase II/*metabolism ; Single-Cell Analysis/methods ; Time Factors ; Transcription Elongation, Genetic/drug effects ; *Transcription, Genetic
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
    Published by American Association for the Advancement of Science (AAAS)
    Location Call Number Expected Availability
    BibTip Others were also interested in ...
    PAPER CURRENT
  • 68
    facet.materialart.
    Unknown
    Paleoanthropology. Stunning skull gives a fresh portrait of early humans (2013)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 2013-10-19
    Description: 〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Gibbons, Ann -- New York, N.Y. -- Science. 2013 Oct 18;342(6156):297-8. doi: 10.1126/science.342.6156.297.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/24136941" target="_blank"〉PubMed〈/a〉
    Keywords: *Anthropology ; *Biological Evolution ; *Fossils ; Georgia (Republic) ; History, Ancient ; Humans ; Skull/*anatomy & histology/*growth & development
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
    Published by American Association for the Advancement of Science (AAAS)
    Location Call Number Expected Availability
    BibTip Others were also interested in ...
    PAPER CURRENT
  • 69
    facet.materialart.
    Unknown
    The thousand-year graveyard (2013)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 2013-12-18
    Description: 〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Gibbons, Ann -- New York, N.Y. -- Science. 2013 Dec 13;342(6164):1306-10. doi: 10.1126/science.342.6164.1306.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/24337272" target="_blank"〉PubMed〈/a〉
    Keywords: Aged ; Anthropology, Physical ; Archaeology ; *Cause of Death ; Cemeteries/*history ; DNA, Bacterial/isolation & purification ; Epidemics/*history ; Female ; History, Medieval ; Humans ; Italy/epidemiology ; Jaw/microbiology ; Plague/epidemiology/history ; Skull/microbiology ; Tooth/microbiology ; Yersinia pestis/classification/genetics/isolation & purification
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
    Published by American Association for the Advancement of Science (AAAS)
    Location Call Number Expected Availability
    BibTip Others were also interested in ...
    PAPER CURRENT
  • 70
    facet.materialart.
    Unknown
    The Age of Man: outpacing evolution (2013)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 2013-06-15
    Description: 〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Settele, Josef -- Spangenberg, Joachim H -- New York, N.Y. -- Science. 2013 Jun 14;340(6138):1287. doi: 10.1126/science.340.6138.1287-b.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/23766311" target="_blank"〉PubMed〈/a〉
    Keywords: Agriculture/*history ; Archaeology/*trends ; *Geological Phenomena ; Humans
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
    Published by American Association for the Advancement of Science (AAAS)
    Location Call Number Expected Availability
    BibTip Others were also interested in ...
    PAPER CURRENT
  • 71
    facet.materialart.
    Unknown
    Cell biology. Rapid aging rescue? (2013)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 2013-06-15
    Description: 〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Johnson, Thomas E -- New York, N.Y. -- Science. 2013 Jun 14;340(6138):1299-300. doi: 10.1126/science.1240843.〈br /〉〈span class="detail_caption"〉Author address: 〈/span〉Institute for Behavioral Genetics and Department of Integrative Physiology, Box 447, University of Colorado, Boulder 80309, USA. johnsont@colorado.edu〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/23766322" target="_blank"〉PubMed〈/a〉
    Keywords: Animals ; *Gene Knockout Techniques ; Humans ; Membrane Proteins/*metabolism ; Metalloendopeptidases/*metabolism ; Progeria/*therapy ; Protein Methyltransferases/*genetics/*metabolism
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
    Published by American Association for the Advancement of Science (AAAS)
    Location Call Number Expected Availability
    BibTip Others were also interested in ...
    PAPER CURRENT
  • 72
    facet.materialart.
    Unknown
    Cancer. Potential of the synthetic lethality principle (2013)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 2013-11-16
    Description: 〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Nijman, Sebastian M B -- Friend, Stephen H -- New York, N.Y. -- Science. 2013 Nov 15;342(6160):809-11. doi: 10.1126/science.1244669.〈br /〉〈span class="detail_caption"〉Author address: 〈/span〉CeMM Research Center for Molecular Medicine of the Austrian Academy of Sciences, Vienna, Austria.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/24233712" target="_blank"〉PubMed〈/a〉
    Keywords: Animals ; Drosophila melanogaster/genetics ; Gene Targeting ; *Genes, Lethal ; *Genes, Modifier ; Genetic Therapy/*methods ; Humans ; Immunotherapy ; Molecular Targeted Therapy ; Mutation ; Neoplasms/*genetics/*therapy ; Saccharomyces cerevisiae/genetics ; Tumor Suppressor Proteins/genetics
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
    Published by American Association for the Advancement of Science (AAAS)
    Location Call Number Expected Availability
    BibTip Others were also interested in ...
    PAPER CURRENT
  • 73
    facet.materialart.
    Unknown
    Evolution. Protein expression under pressure (2013)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 2013-11-30
    Description: 〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Vogel, Christine -- New York, N.Y. -- Science. 2013 Nov 29;342(6162):1052-3. doi: 10.1126/science.1247833.〈br /〉〈span class="detail_caption"〉Author address: 〈/span〉New York University, Center for Genomics and Systems Biology, New York, NY 10003, USA.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/24288321" target="_blank"〉PubMed〈/a〉
    Keywords: Animals ; *Evolution, Molecular ; *Gene Expression Regulation ; Humans ; Macaca mulatta/*genetics ; Pan troglodytes/*genetics ; Protein Biosynthesis/*genetics ; RNA, Messenger/*biosynthesis ; *Selection, Genetic ; *Transcription, Genetic
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
    Published by American Association for the Advancement of Science (AAAS)
    Location Call Number Expected Availability
    BibTip Others were also interested in ...
    PAPER CURRENT
  • 74
    facet.materialart.
    Unknown
    Retrospective. Michael Neuberger (1953-2013) (2013)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 2013-12-18
    Description: 〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Sale, Julian E -- Patel, Ketan J -- Batista, Facundo D -- MC_U105178808/Medical Research Council/United Kingdom -- MC_U105178811/Medical Research Council/United Kingdom -- New York, N.Y. -- Science. 2013 Dec 13;342(6164):1335. doi: 10.1126/science.1248808.〈br /〉〈span class="detail_caption"〉Author address: 〈/span〉MRC Laboratory of Molecular Biology, Cambridge, UK.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/24337288" target="_blank"〉PubMed〈/a〉
    Keywords: Allergy and Immunology/*history ; Animals ; Antibodies, Monoclonal, Humanized/*history ; *Antibody Diversity ; Biomedical Engineering/*history ; Great Britain ; History, 20th Century ; History, 21st Century ; Humans ; Mice ; Molecular Biology/*history
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
    Published by American Association for the Advancement of Science (AAAS)
    Location Call Number Expected Availability
    BibTip Others were also interested in ...
    PAPER CURRENT
  • 75
    facet.materialart.
    Unknown
    Prediction error governs pharmacologically induced amnesia for learned fear (2013)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 2013-02-16
    Description: Although reconsolidation opens up new avenues to erase excessive fear memory, subtle boundary conditions put constraints on retrieval-induced plasticity. Reconsolidation may only take place when memory reactivation involves an experience that engages new learning (prediction error). Thus far, it has not been possible to determine the optimal degree of novelty required for destabilizing the memory. The occurrence of prediction error could only be inferred from the observation of a reconsolidation process itself. Here, we provide a noninvasive index of memory destabilization that is independent from the occurrence of reconsolidation. Using this index, we show in humans that prediction error is (i) a necessary condition for reconsolidation of associative fear memory and (ii) determined by the interaction between original learning and retrieval. Insight into the process of memory updating is crucial for understanding the optimal and boundary conditions on reconsolidation and provides a clear guide for the development of reconsolidation-based treatments.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Sevenster, Dieuwke -- Beckers, Tom -- Kindt, Merel -- New York, N.Y. -- Science. 2013 Feb 15;339(6121):830-3. doi: 10.1126/science.1231357.〈br /〉〈span class="detail_caption"〉Author address: 〈/span〉Department of Clinical Psychology, University of Amsterdam, Amsterdam, Netherlands.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/23413355" target="_blank"〉PubMed〈/a〉
    Keywords: 1-Propanol/administration & dosage ; Amnesia/chemically induced/*psychology ; Conditioning (Psychology)/drug effects ; Fear/drug effects/*psychology ; Female ; Humans ; Learning/drug effects/*physiology ; Male ; Mental Recall/drug effects/physiology ; Models, Psychological ; Reinforcement Schedule ; Young Adult
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
    Published by American Association for the Advancement of Science (AAAS)
    Location Call Number Expected Availability
    BibTip Others were also interested in ...
    PAPER CURRENT
  • 76
    facet.materialart.
    Unknown
    Structural and functional brain networks: from connections to cognition (2013)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 2013-11-02
    Description: How rich functionality emerges from the invariant structural architecture of the brain remains a major mystery in neuroscience. Recent applications of network theory and theoretical neuroscience to large-scale brain networks have started to dissolve this mystery. Network analyses suggest that hierarchical modular brain networks are particularly suited to facilitate local (segregated) neuronal operations and the global integration of segregated functions. Although functional networks are constrained by structural connections, context-sensitive integration during cognition tasks necessarily entails a divergence between structural and functional networks. This degenerate (many-to-one) function-structure mapping is crucial for understanding the nature of brain networks. The emergence of dynamic functional networks from static structural connections calls for a formal (computational) approach to neuronal information processing that may resolve this dialectic between structure and function.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Park, Hae-Jeong -- Friston, Karl -- 088130/Wellcome Trust/United Kingdom -- 091593/Wellcome Trust/United Kingdom -- Wellcome Trust/United Kingdom -- New York, N.Y. -- Science. 2013 Nov 1;342(6158):1238411. doi: 10.1126/science.1238411.〈br /〉〈span class="detail_caption"〉Author address: 〈/span〉Department of Nuclear Medicine, Psychiatry, Severance Biomedical Science Institute, BK21 Project for Medical Science, Yonsei University College of Medicine, Seoul, Republic of Korea.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/24179229" target="_blank"〉PubMed〈/a〉
    Keywords: Brain/*physiology/*ultrastructure ; Cognition/*physiology ; Humans ; *Models, Neurological ; Nerve Net/*physiology/*ultrastructure
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
    Published by American Association for the Advancement of Science (AAAS)
    Location Call Number Expected Availability
    BibTip Others were also interested in ...
    PAPER CURRENT
  • 77
    facet.materialart.
    Unknown
    Climate change. Humans fueled global warming millennia ago (2013)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 2013-11-23
    Description: 〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Kerr, Richard A -- New York, N.Y. -- Science. 2013 Nov 22;342(6161):918. doi: 10.1126/science.342.6161.918.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/24264968" target="_blank"〉PubMed〈/a〉
    Keywords: Atmosphere/*chemistry ; Humans ; Ice Cover/*chemistry ; Industry/*trends ; Methane/*analysis
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
    Published by American Association for the Advancement of Science (AAAS)
    Location Call Number Expected Availability
    BibTip Others were also interested in ...
    PAPER CURRENT
  • 78
    facet.materialart.
    Unknown
    When early hominins got a grip (2013)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 2013-04-27
    Description: 〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Gibbons, Ann -- New York, N.Y. -- Science. 2013 Apr 26;340(6131):426-7. doi: 10.1126/science.340.6131.426-a.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/23620030" target="_blank"〉PubMed〈/a〉
    Keywords: Animals ; Anthropology, Physical/*history ; Hand/*anatomy & histology/*physiology ; Hand Bones/*anatomy & histology ; *Hand Strength ; History, Ancient ; Hominidae/*physiology ; Humans
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
    Published by American Association for the Advancement of Science (AAAS)
    Location Call Number Expected Availability
    BibTip Others were also interested in ...
    PAPER CURRENT
  • 79
    facet.materialart.
    Unknown
    Dual use research. New U.S. rules increase oversight of H5N1 studies, other risky science (2013)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 2013-03-02
    Description: 〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Malakoff, David -- Enserink, Martin -- New York, N.Y. -- Science. 2013 Mar 1;339(6123):1025. doi: 10.1126/science.339.6123.1025.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/23449570" target="_blank"〉PubMed〈/a〉
    Keywords: Animals ; Biomedical Research/*standards ; *Guidelines as Topic ; Humans ; Influenza A Virus, H5N1 Subtype/*genetics/*pathogenicity ; Influenza, Human/*prevention & control/*transmission ; Laboratories/standards ; United States
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
    Published by American Association for the Advancement of Science (AAAS)
    Location Call Number Expected Availability
    BibTip Others were also interested in ...
    PAPER CURRENT
  • 80
    facet.materialart.
    Unknown
    Cancer. Fusion for moving (2013)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 2013-11-10
    Description: 〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Clawson, Gary A -- CA170121/CA/NCI NIH HHS/ -- New York, N.Y. -- Science. 2013 Nov 8;342(6159):699-700. doi: 10.1126/science.1244270.〈br /〉〈span class="detail_caption"〉Author address: 〈/span〉Gittlen Cancer Research Foundation, Department of Pathology, and Department of Biochemistry & Molecular Biology, Hershey Medical Center, Pennsylvania State University, Hershey, PA 17033, USA.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/24202164" target="_blank"〉PubMed〈/a〉
    Keywords: Blood Circulation ; Brain Neoplasms/secondary ; Cell Fusion ; Humans ; Hybrid Cells/*pathology ; Macrophages/*pathology ; Melanoma/secondary ; Neoplasm Metastasis/*pathology ; Neoplasms/*pathology ; Neoplastic Cells, Circulating/*pathology ; Neoplastic Stem Cells/*pathology ; Skin Neoplasms/pathology
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
    Published by American Association for the Advancement of Science (AAAS)
    Location Call Number Expected Availability
    BibTip Others were also interested in ...
    PAPER CURRENT
  • 81
    facet.materialart.
    Unknown
    The forgotten malaria (2013)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 2013-11-10
    Description: 〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Vogel, Gretchen -- New York, N.Y. -- Science. 2013 Nov 8;342(6159):684-7. doi: 10.1126/science.342.6159.684.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/24202156" target="_blank"〉PubMed〈/a〉
    Keywords: Child, Preschool ; Communicable Diseases, Emerging/*epidemiology/*parasitology/prevention & control ; Disease Eradication ; Erythrocytes/parasitology ; *Global Health ; Humans ; Malaria, Vivax/*epidemiology/*parasitology/prevention & control ; Neglected Diseases/*epidemiology/*parasitology/prevention & control ; Plasmodium vivax/*growth & development/isolation & purification/pathogenicity ; Prevalence
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
    Published by American Association for the Advancement of Science (AAAS)
    Location Call Number Expected Availability
    BibTip Others were also interested in ...
    PAPER CURRENT
  • 82
    facet.materialart.
    Unknown
    Human rights. A human right to science (2013)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 2013-06-15
    Description: 〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Chapman, Audrey -- Wyndham, Jessica -- New York, N.Y. -- Science. 2013 Jun 14;340(6138):1291. doi: 10.1126/science.1233319.〈br /〉〈span class="detail_caption"〉Author address: 〈/span〉University of Connecticut Health Center, Farmington, CT 06030, USA. achapman@uchc.edu〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/23766315" target="_blank"〉PubMed〈/a〉
    Keywords: *Access to Information ; *Human Rights ; Humans ; *Science ; United Nations
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
    Published by American Association for the Advancement of Science (AAAS)
    Location Call Number Expected Availability
    BibTip Others were also interested in ...
    PAPER CURRENT
  • 83
    facet.materialart.
    Unknown
    Optimizing peer review of software code--response (2013)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 2013-07-23
    Description: 〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Joppa, Lucas N -- Gavaghan, David -- Harper, Richard -- Takeda, Kenji -- Emmott, Stephen -- New York, N.Y. -- Science. 2013 Jul 19;341(6143):237. doi: 10.1126/science.341.6143.237-a.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/23869003" target="_blank"〉PubMed〈/a〉
    Keywords: Computer Simulation/*utilization ; Humans ; Research/*trends ; *Software
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
    Published by American Association for the Advancement of Science (AAAS)
    Location Call Number Expected Availability
    BibTip Others were also interested in ...
    PAPER CURRENT
  • 84
    facet.materialart.
    Unknown
    Malaria as lifesaving therapy (2013)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 2013-11-10
    Description: 〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Vogel, Gretchen -- New York, N.Y. -- Science. 2013 Nov 8;342(6159):686. doi: 10.1126/science.342.6159.686.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/24202157" target="_blank"〉PubMed〈/a〉
    Keywords: History, 20th Century ; Humans ; Hyperthermia, Induced/history/*methods ; Malaria, Falciparum/*blood/history ; Neurosyphilis/history/immunology/*therapy ; *Plasmodium falciparum
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
    Published by American Association for the Advancement of Science (AAAS)
    Location Call Number Expected Availability
    BibTip Others were also interested in ...
    PAPER CURRENT
  • 85
    facet.materialart.
    Unknown
    IBI series winner. Exploring the evolution of human mate preference (2013)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 2013-11-30
    Description: 〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Foster, Valerie -- New York, N.Y. -- Science. 2013 Nov 29;342(6162):1060-1. doi: 10.1126/science.1230005.〈br /〉〈span class="detail_caption"〉Author address: 〈/span〉Natural Sciences Division, Pasadena City College, 1570 East Colorado Boulevard, Pasadena, CA 91106, USA.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/24288326" target="_blank"〉PubMed〈/a〉
    Keywords: Adult ; Courtship/*psychology ; Female ; Humans ; Male ; Marriage/*psychology ; Personality ; Problem-Based Learning/*methods ; Selection, Genetic ; Voice Quality ; Young Adult
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
    Published by American Association for the Advancement of Science (AAAS)
    Location Call Number Expected Availability
    BibTip Others were also interested in ...
    PAPER CURRENT
  • 86
    facet.materialart.
    Unknown
    Transmission studies resume for avian flu (2013)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 2013-01-25
    Description: 〈br /〉〈br /〉〈a href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3838856/" target="_blank"〉〈img src="https://static.pubmed.gov/portal/portal3rc.fcgi/4089621/img/3977009" border="0"〉〈/a〉   〈a href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3838856/" target="_blank"〉This paper as free author manuscript - peer-reviewed and accepted for publication〈/a〉〈br /〉〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Fouchier, Ron A M -- Garcia-Sastre, Adolfo -- Kawaoka, Yoshihiro -- Barclay, Wendy S -- Bouvier, Nicole M -- Brown, Ian H -- Capua, Ilaria -- Chen, Hualan -- Compans, Richard W -- Couch, Robert B -- Cox, Nancy J -- Doherty, Peter C -- Donis, Ruben O -- Feldmann, Heinz -- Guan, Yi -- Katz, Jacqueline M -- Kiselev, Oleg I -- Klenk, H D -- Kobinger, Gary -- Liu, Jinhua -- Liu, Xiufan -- Lowen, Anice -- Mettenleiter, Thomas C -- Osterhaus, Albert D M E -- Palese, Peter -- Peiris, J S Malik -- Perez, Daniel R -- Richt, Jurgen A -- Schultz-Cherry, Stacey -- Steel, John -- Subbarao, Kanta -- Swayne, David E -- Takimoto, Toru -- Tashiro, Masato -- Taubenberger, Jeffery K -- Thomas, Paul G -- Tripp, Ralph A -- Tumpey, Terrence M -- Webby, Richard J -- Webster, Robert G -- ZIA AI001088-01/Intramural NIH HHS/ -- ZIA AI001088-02/Intramural NIH HHS/ -- ZIA AI001088-03/Intramural NIH HHS/ -- ZIA AI001088-04/Intramural NIH HHS/ -- ZIA AI001088-05/Intramural NIH HHS/ -- New York, N.Y. -- Science. 2013 Feb 1;339(6119):520-1. doi: 10.1126/science.1235140. Epub 2013 Jan 23.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/23345603" target="_blank"〉PubMed〈/a〉
    Keywords: Animals ; Biomedical Research/*trends ; Birds ; Humans ; *Influenza A Virus, H5N1 Subtype ; Influenza in Birds/*transmission/*virology ; Influenza, Human/*transmission/*virology
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
    Published by American Association for the Advancement of Science (AAAS)
    Location Call Number Expected Availability
    BibTip Others were also interested in ...
    PAPER CURRENT
  • 87
    facet.materialart.
    Unknown
    Near-complete extinction of native small mammal fauna 25 years after forest fragmentation (2013)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 2013-09-28
    Description: Tropical forests continue to be felled and fragmented around the world. A key question is how rapidly species disappear from forest fragments and how quickly humans must restore forest connectivity to minimize extinctions. We surveyed small mammals on forest islands in Chiew Larn Reservoir in Thailand 5 to 7 and 25 to 26 years after isolation and observed the near-total loss of native small mammals within 5 years from 〈10-hectare (ha) fragments and within 25 years from 10- to 56-ha fragments. Based on our results, we developed an island biogeographic model and estimated mean extinction half-life (50% of resident species disappearing) to be 13.9 years. These catastrophic extinctions were probably partly driven by an invasive rat species; such biotic invasions are becoming increasingly common in human-modified landscapes. Our results are thus particularly relevant to other fragmented forest landscapes and suggest that small fragments are potentially even more vulnerable to biodiversity loss than previously thought.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Gibson, Luke -- Lynam, Antony J -- Bradshaw, Corey J A -- He, Fangliang -- Bickford, David P -- Woodruff, David S -- Bumrungsri, Sara -- Laurance, William F -- New York, N.Y. -- Science. 2013 Sep 27;341(6153):1508-10. doi: 10.1126/science.1240495.〈br /〉〈span class="detail_caption"〉Author address: 〈/span〉Department of Biological Sciences, National University of Singapore, 14 Science Drive 4, Singapore 117543, Singapore. lggibson@nus.edu.sg〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/24072921" target="_blank"〉PubMed〈/a〉
    Keywords: Animals ; Biodiversity ; *Conservation of Natural Resources ; *Extinction, Biological ; Humans ; Islands ; Mammals/*classification ; Thailand ; *Trees
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
    Published by American Association for the Advancement of Science (AAAS)
    Location Call Number Expected Availability
    BibTip Others were also interested in ...
    PAPER CURRENT
  • 88
    facet.materialart.
    Unknown
    RNA-guided human genome engineering via Cas9 (2013)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 2013-01-05
    Description: Bacteria and archaea have evolved adaptive immune defenses, termed clustered regularly interspaced short palindromic repeats (CRISPR)/CRISPR-associated (Cas) systems, that use short RNA to direct degradation of foreign nucleic acids. Here, we engineer the type II bacterial CRISPR system to function with custom guide RNA (gRNA) in human cells. For the endogenous AAVS1 locus, we obtained targeting rates of 10 to 25% in 293T cells, 13 to 8% in K562 cells, and 2 to 4% in induced pluripotent stem cells. We show that this process relies on CRISPR components; is sequence-specific; and, upon simultaneous introduction of multiple gRNAs, can effect multiplex editing of target loci. We also compute a genome-wide resource of ~190 K unique gRNAs targeting ~40.5% of human exons. Our results establish an RNA-guided editing tool for facile, robust, and multiplexable human genome engineering.〈br /〉〈br /〉〈a href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3712628/" target="_blank"〉〈img src="https://static.pubmed.gov/portal/portal3rc.fcgi/4089621/img/3977009" border="0"〉〈/a〉   〈a href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3712628/" target="_blank"〉This paper as free author manuscript - peer-reviewed and accepted for publication〈/a〉〈br /〉〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Mali, Prashant -- Yang, Luhan -- Esvelt, Kevin M -- Aach, John -- Guell, Marc -- DiCarlo, James E -- Norville, Julie E -- Church, George M -- P50 HG005550/HG/NHGRI NIH HHS/ -- New York, N.Y. -- Science. 2013 Feb 15;339(6121):823-6. doi: 10.1126/science.1232033. Epub 2013 Jan 3.〈br /〉〈span class="detail_caption"〉Author address: 〈/span〉Department of Genetics, Harvard Medical School, Boston, MA 02115, USA.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/23287722" target="_blank"〉PubMed〈/a〉
    Keywords: Caspase 9/*chemistry/genetics ; Chromosomes, Human, Pair 19/genetics ; Codon/genetics ; DNA Cleavage ; Exons ; Gene Targeting/*methods ; Genetic Engineering/*methods ; Genetic Loci ; Genome, Human/*genetics ; Humans ; Induced Pluripotent Stem Cells ; Inverted Repeat Sequences/*genetics ; K562 Cells ; RNA/*chemistry/genetics
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
    Published by American Association for the Advancement of Science (AAAS)
    Location Call Number Expected Availability
    BibTip Others were also interested in ...
    PAPER CURRENT
  • 89
    facet.materialart.
    Unknown
    Neurodevelopment. Lab dishes up mini-brains (2013)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 2013-08-31
    Description: 〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Vogel, Gretchen -- New York, N.Y. -- Science. 2013 Aug 30;341(6149):946-7. doi: 10.1126/science.341.6149.946.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/23990534" target="_blank"〉PubMed〈/a〉
    Keywords: Brain/*embryology ; Brain Diseases/etiology/genetics ; *Cell Culture Techniques ; Humans ; *Models, Neurological ; Neural Stem Cells ; *Neurogenesis ; Organoids/*embryology ; Pluripotent Stem Cells
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
    Published by American Association for the Advancement of Science (AAAS)
    Location Call Number Expected Availability
    BibTip Others were also interested in ...
    PAPER CURRENT
  • 90
    facet.materialart.
    Unknown
    Biochemistry. Have your PIC! (2013)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 2013-11-10
    Description: 〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Malik, Sohail -- Roeder, Robert G -- New York, N.Y. -- Science. 2013 Nov 8;342(6159):706-7. doi: 10.1126/science.1246170.〈br /〉〈span class="detail_caption"〉Author address: 〈/span〉Laboratory of Biochemistry and Molecular Biology, Rockefeller University, 1230 York Avenue, New York, NY 10065, USA.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/24202169" target="_blank"〉PubMed〈/a〉
    Keywords: Catalytic Domain ; Cryoelectron Microscopy ; Crystallography ; DNA/*chemistry ; Humans ; *Promoter Regions, Genetic ; Protein Conformation ; RNA Polymerase II/*chemistry ; Transcription Factors, General/*chemistry ; *Transcription Initiation, Genetic
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
    Published by American Association for the Advancement of Science (AAAS)
    Location Call Number Expected Availability
    BibTip Others were also interested in ...
    PAPER CURRENT
  • 91
    facet.materialart.
    Unknown
    Education guidelines fail to inspire (2013)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 2013-06-01
    Description: 〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Pasachoff, Jay M -- New York, N.Y. -- Science. 2013 May 31;340(6136):1041. doi: 10.1126/science.340.6136.1041-a.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/23723217" target="_blank"〉PubMed〈/a〉
    Keywords: Education, Professional/*methods ; Engineering/*education ; Humans ; *Laboratories ; Language Arts/*standards ; Mathematics/*education ; Physics/*education ; Schools/*standards ; Science/*education ; Teaching/*methods ; Technology/*education ; *Universities ; *User-Computer Interface
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
    Published by American Association for the Advancement of Science (AAAS)
    Location Call Number Expected Availability
    BibTip Others were also interested in ...
    PAPER CURRENT
  • 92
    facet.materialart.
    Unknown
    Evolution. The hidden codes that shape protein evolution (2013)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 2013-12-18
    Description: 〈br /〉〈br /〉〈a href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4167339/" target="_blank"〉〈img src="https://static.pubmed.gov/portal/portal3rc.fcgi/4089621/img/3977009" border="0"〉〈/a〉   〈a href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4167339/" target="_blank"〉This paper as free author manuscript - peer-reviewed and accepted for publication〈/a〉〈br /〉〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Weatheritt, Robert J -- Babu, M Madan -- MC_U105185859/Medical Research Council/United Kingdom -- Medical Research Council/United Kingdom -- New York, N.Y. -- Science. 2013 Dec 13;342(6164):1325-6. doi: 10.1126/science.1248425.〈br /〉〈span class="detail_caption"〉Author address: 〈/span〉MRC Laboratory of Molecular Biology, Francis Crick Avenue, Cambridge CB2 0QH, UK.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/24337281" target="_blank"〉PubMed〈/a〉
    Keywords: Codon/*genetics ; *Evolution, Molecular ; *Exome ; *Exons ; *Genome, Human ; Humans ; Transcription Factors/*metabolism
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
    Published by American Association for the Advancement of Science (AAAS)
    Location Call Number Expected Availability
    BibTip Others were also interested in ...
    PAPER CURRENT
  • 93
    facet.materialart.
    Unknown
    Research ethics. Regulation of online social network studies (2013)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 2013-01-12
    Description: 〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Shapiro, R Benjamin -- Ossorio, Pilar N -- New York, N.Y. -- Science. 2013 Jan 11;339(6116):144-5. doi: 10.1126/science.1219025.〈br /〉〈span class="detail_caption"〉Author address: 〈/span〉Tufts University, Medford, MA 02155, USA.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/23307724" target="_blank"〉PubMed〈/a〉
    Keywords: Adolescent ; Ethics Committees, Research ; *Ethics, Research ; Humans ; Informed Consent ; Internet ; *Research Subjects ; *Social Media ; *Social Networking ; *Video Games
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
    Published by American Association for the Advancement of Science (AAAS)
    Location Call Number Expected Availability
    BibTip Others were also interested in ...
    PAPER CURRENT
  • 94
    facet.materialart.
    Unknown
    Loss of function of the melanocortin 2 receptor accessory protein 2 is associated with mammalian obesity (2013)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 2013-07-23
    Description: Melanocortin receptor accessory proteins (MRAPs) modulate signaling of melanocortin receptors in vitro. To investigate the physiological role of brain-expressed melanocortin 2 receptor accessory protein 2 (MRAP2), we characterized mice with whole-body and brain-specific targeted deletion of Mrap2, both of which develop severe obesity at a young age. Mrap2 interacts directly with melanocortin 4 receptor (Mc4r), a protein previously implicated in mammalian obesity, and it enhances Mc4r-mediated generation of the second messenger cyclic adenosine monophosphate, suggesting that alterations in Mc4r signaling may be one mechanism underlying the association between Mrap2 disruption and obesity. In a study of humans with severe, early-onset obesity, we found four rare, potentially pathogenic genetic variants in MRAP2, suggesting that the gene may also contribute to body weight regulation in humans.〈br /〉〈br /〉〈a href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3788688/" target="_blank"〉〈img src="https://static.pubmed.gov/portal/portal3rc.fcgi/4089621/img/3977009" border="0"〉〈/a〉   〈a href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3788688/" target="_blank"〉This paper as free author manuscript - peer-reviewed and accepted for publication〈/a〉〈br /〉〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Asai, Masato -- Ramachandrappa, Shwetha -- Joachim, Maria -- Shen, Yuan -- Zhang, Rong -- Nuthalapati, Nikhil -- Ramanathan, Visali -- Strochlic, David E -- Ferket, Peter -- Linhart, Kirsten -- Ho, Caroline -- Novoselova, Tatiana V -- Garg, Sumedha -- Ridderstrale, Martin -- Marcus, Claude -- Hirschhorn, Joel N -- Keogh, Julia M -- O'Rahilly, Stephen -- Chan, Li F -- Clark, Adrian J -- Farooqi, I Sadaf -- Majzoub, Joseph A -- 098497/Wellcome Trust/United Kingdom -- G0802796/Medical Research Council/United Kingdom -- G0900554/Medical Research Council/United Kingdom -- G9824984/Medical Research Council/United Kingdom -- P30-HD18655/HD/NICHD NIH HHS/ -- R01 DK075787/DK/NIDDK NIH HHS/ -- R01DK075787/DK/NIDDK NIH HHS/ -- T32 DK007699/DK/NIDDK NIH HHS/ -- T32 MH020017/MH/NIMH NIH HHS/ -- Wellcome Trust/United Kingdom -- New York, N.Y. -- Science. 2013 Jul 19;341(6143):275-8. doi: 10.1126/science.1233000.〈br /〉〈span class="detail_caption"〉Author address: 〈/span〉Division of Endocrinology, Department of Medicine, Boston Children's Hospital, Harvard Medical School, 300 Longwood Avenue, Boston, MA 02115, USA.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/23869016" target="_blank"〉PubMed〈/a〉
    Keywords: Adolescent ; Animals ; Body Mass Index ; Body Weight/*genetics ; Carrier Proteins/*genetics ; Child ; Child, Preschool ; Energy Metabolism/genetics ; Female ; Gene Deletion ; Humans ; Male ; Mice ; Mice, Knockout ; Obesity/*genetics/metabolism ; Receptor Activity-Modifying Proteins/genetics/*metabolism ; Receptor, Melanocortin, Type 4/genetics/*metabolism ; Young Adult
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
    Published by American Association for the Advancement of Science (AAAS)
    Location Call Number Expected Availability
    BibTip Others were also interested in ...
    PAPER CURRENT
  • 95
    facet.materialart.
    Unknown
    Stress in puberty unmasks latent neuropathological consequences of prenatal immune activation in mice (2013)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 2013-03-02
    Description: Prenatal infection and exposure to traumatizing experiences during peripuberty have each been associated with increased risk for neuropsychiatric disorders. Evidence is lacking for the cumulative impact of such prenatal and postnatal environmental challenges on brain functions and vulnerability to psychiatric disease. Here, we show in a translational mouse model that combined exposure to prenatal immune challenge and peripubertal stress induces synergistic pathological effects on adult behavioral functions and neurochemistry. We further demonstrate that the prenatal insult markedly increases the vulnerability of the pubescent offspring to brain immune changes in response to stress. Our findings reveal interactions between two adverse environmental factors that have individually been associated with neuropsychiatric disease and support theories that mental illnesses with delayed onsets involve multiple environmental hits.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Giovanoli, Sandra -- Engler, Harald -- Engler, Andrea -- Richetto, Juliet -- Voget, Mareike -- Willi, Roman -- Winter, Christine -- Riva, Marco A -- Mortensen, Preben B -- Feldon, Joram -- Schedlowski, Manfred -- Meyer, Urs -- New York, N.Y. -- Science. 2013 Mar 1;339(6123):1095-9. doi: 10.1126/science.1228261.〈br /〉〈span class="detail_caption"〉Author address: 〈/span〉Physiology and Behavior Laboratory, Swiss Federal Institute of Technology (ETH) Zurich, 8603 Schwerzenbach, Switzerland.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/23449593" target="_blank"〉PubMed〈/a〉
    Keywords: Animals ; Cytokines/immunology ; Disease Models, Animal ; Female ; Humans ; Mental Disorders/*immunology ; Mice ; Mice, Inbred C57BL ; Poly I-C/immunology/pharmacology ; Pregnancy ; Prenatal Exposure Delayed Effects/*immunology/virology ; Puberty/*immunology ; Stress, Physiological/*immunology
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
    Published by American Association for the Advancement of Science (AAAS)
    Location Call Number Expected Availability
    BibTip Others were also interested in ...
    PAPER CURRENT
  • 96
    facet.materialart.
    Unknown
    Research funding. A framework for decisions about research with HPAI H5N1 viruses (2013)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 2013-02-23
    Description: 〈br /〉〈br /〉〈a href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4011183/" target="_blank"〉〈img src="https://static.pubmed.gov/portal/portal3rc.fcgi/4089621/img/3977009" border="0"〉〈/a〉   〈a href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4011183/" target="_blank"〉This paper as free author manuscript - peer-reviewed and accepted for publication〈/a〉〈br /〉〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Patterson, Amy P -- Tabak, Lawrence A -- Fauci, Anthony S -- Collins, Francis S -- Howard, Sally -- Z99 AI999999/Intramural NIH HHS/ -- Z99 OD999999/Intramural NIH HHS/ -- New York, N.Y. -- Science. 2013 Mar 1;339(6123):1036-7. doi: 10.1126/science.1236194. Epub 2013 Feb 21.〈br /〉〈span class="detail_caption"〉Author address: 〈/span〉National Institutes of Health, Bethesda, MD 20892, USA. pattersa@od.nih.gov〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/23429700" target="_blank"〉PubMed〈/a〉
    Keywords: Animals ; Biomedical Research/*education ; Birds ; Guidelines as Topic ; Humans ; Influenza A Virus, H5N1 Subtype/genetics/*pathogenicity ; Influenza in Birds/*transmission ; Influenza, Human/*transmission ; Safety
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
    Published by American Association for the Advancement of Science (AAAS)
    Location Call Number Expected Availability
    BibTip Others were also interested in ...
    PAPER CURRENT
  • 97
    facet.materialart.
    Unknown
    Natural systems in changing climates. Once and future climate change. Introduction (2013)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 2013-08-03
    Description: 〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Ash, Caroline -- Culotta, Elizabeth -- Fahrenkamp-Uppenbrink, Julia -- Malakoff, David -- Smith, Jesse -- Sugden, Andrew -- Vignieri, Sacha -- New York, N.Y. -- Science. 2013 Aug 2;341(6145):472-3. doi: 10.1126/science.341.6145.472.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/23908216" target="_blank"〉PubMed〈/a〉
    Keywords: *Climate Change ; Forecasting ; Humans
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
    Published by American Association for the Advancement of Science (AAAS)
    Location Call Number Expected Availability
    BibTip Others were also interested in ...
    PAPER CURRENT
  • 98
    facet.materialart.
    Unknown
    Microbiology. Genomes from metagenomics (2013)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 2013-11-30
    Description: 〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Sharon, Itai -- Banfield, Jillian F -- New York, N.Y. -- Science. 2013 Nov 29;342(6162):1057-8. doi: 10.1126/science.1247023.〈br /〉〈span class="detail_caption"〉Author address: 〈/span〉Department of Earth and Planetary Science, University of California, Berkeley, CA 94720, USA.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/24288324" target="_blank"〉PubMed〈/a〉
    Keywords: Drug Resistance, Microbial/genetics ; Gastrointestinal Tract/microbiology ; Genome, Bacterial/*genetics ; Humans ; Infant ; Metagenomics/*methods ; Single-Cell Analysis/methods ; Virulence/genetics
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
    Published by American Association for the Advancement of Science (AAAS)
    Location Call Number Expected Availability
    BibTip Others were also interested in ...
    PAPER CURRENT
  • 99
    facet.materialart.
    Unknown
    Fueling immunity: insights into metabolism and lymphocyte function (2013)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 2013-10-12
    Description: Lymphocytes face major metabolic challenges upon activation. They must meet the bioenergetic and biosynthetic demands of increased cell proliferation and also adapt to changing environmental conditions, in which nutrients and oxygen may be limiting. An emerging theme in immunology is that metabolic reprogramming and lymphocyte activation are intricately linked. However, why T cells adopt specific metabolic programs and the impact that these programs have on T cell function and, ultimately, immunological outcome remain unclear. Research on tumor cell metabolism has provided valuable insight into metabolic pathways important for cell proliferation and the influence of metabolites themselves on signal transduction and epigenetic programming. In this Review, we highlight emerging concepts regarding metabolic reprogramming in proliferating cells and discuss their potential impact on T cell fate and function.〈br /〉〈br /〉〈a href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4486656/" target="_blank"〉〈img src="https://static.pubmed.gov/portal/portal3rc.fcgi/4089621/img/3977009" border="0"〉〈/a〉   〈a href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4486656/" target="_blank"〉This paper as free author manuscript - peer-reviewed and accepted for publication〈/a〉〈br /〉〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Pearce, Erika L -- Poffenberger, Maya C -- Chang, Chih-Hao -- Jones, Russell G -- AI091965/AI/NIAID NIH HHS/ -- CA158823/CA/NCI NIH HHS/ -- MOP-93799/Canadian Institutes of Health Research/Canada -- R01 AI091965/AI/NIAID NIH HHS/ -- R01 CA181125/CA/NCI NIH HHS/ -- New York, N.Y. -- Science. 2013 Oct 11;342(6155):1242454. doi: 10.1126/science.1242454.〈br /〉〈span class="detail_caption"〉Author address: 〈/span〉Department of Pathology and Immunology, Washington University School of Medicine, St. Louis, MO 63110, USA. erikapearce@path.wustl.edu〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/24115444" target="_blank"〉PubMed〈/a〉
    Keywords: Animals ; Carrier Proteins/metabolism ; Cell Differentiation ; Cell Proliferation ; *Citric Acid Cycle ; Gene Expression Regulation ; *Glycolysis ; Humans ; Ketoglutaric Acids/metabolism ; *Lymphocyte Activation ; Membrane Proteins/metabolism ; Mitochondria/immunology/metabolism ; Neoplasms/immunology/metabolism ; Protein Kinases/metabolism ; Protein-Serine-Threonine Kinases/metabolism ; T-Lymphocytes/*immunology/*metabolism ; Thyroid Hormones/metabolism
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
    Published by American Association for the Advancement of Science (AAAS)
    Location Call Number Expected Availability
    BibTip Others were also interested in ...
    PAPER CURRENT
  • 100
    facet.materialart.
    Unknown
    Public health. DNA identification after conflict or disaster (2013)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 2013-09-14
    Description: 〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉London, Alex John -- Parker, Lisa S -- Aronson, Jay D -- R01 HG005702/HG/NHGRI NIH HHS/ -- New York, N.Y. -- Science. 2013 Sep 13;341(6151):1178-9. doi: 10.1126/science.1238085.〈br /〉〈span class="detail_caption"〉Author address: 〈/span〉Center for Ethics and Policy, Carnegie Mellon University, Pittsburgh, PA 15213, USA. ajlondon@andrew.cmu.edu〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/24031004" target="_blank"〉PubMed〈/a〉
    Keywords: *Access to Information ; *Crime Victims ; *DNA Fingerprinting ; *Disasters ; Family ; *Forensic Genetics ; Humans ; International Cooperation
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
    Published by American Association for the Advancement of Science (AAAS)
    Location Call Number Expected Availability
    BibTip Others were also interested in ...
    PAPER CURRENT
Close ⊗
This website uses cookies and the analysis tool Matomo. More information can be found here...