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  • Male  (129)
  • Rat  (39)
  • Immunocytochemistry
  • American Association for the Advancement of Science (AAAS)  (129)
  • Springer  (56)
  • Blackwell Publishing Ltd
  • International Union of Crystallography
  • 1980-1984  (185)
  • 1970-1974
  • 1925-1929
  • 1980  (185)
Collection
Keywords
Publisher
  • American Association for the Advancement of Science (AAAS)  (129)
  • Springer  (56)
  • Blackwell Publishing Ltd
  • International Union of Crystallography
Years
  • 1980-1984  (185)
  • 1970-1974
  • 1925-1929
Year
  • 101
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    Interchangeability of stress and amphetamine in sensitization (1980)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1980-01-18
    Description: In view of similarities between the behavioral, biochemical, and electrophysiological effects of amphetamine and stress, we tested the hypothesis that presentation of a stressor, mild tail pressure, can sensitize an animal to the later effects of amphetamine, and vice versa. Our findings supported this hypothesis and suggest that amphetamine and at least some stressors may be interchangeable in their ability to induce a sensitization. The data raise the possibility that stress might be a common variable contributing to both amphetamine psychosis and some forms of schizophrenia.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Antelman, S M -- Eichler, A J -- Black, C A -- Kocan, D -- New York, N.Y. -- Science. 1980 Jan 18;207(4428):329-31.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/7188649" target="_blank"〉PubMed〈/a〉
    Keywords: Animals ; Behavior, Animal/drug effects/*physiology ; Dextroamphetamine/*pharmacology ; Dopamine/physiology ; Dose-Response Relationship, Drug ; Haloperidol/pharmacology ; Humans ; Male ; Rats ; Schizophrenia/physiopathology ; Stereotyped Behavior/drug effects ; Stress, Physiological/*physiopathology
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
    Published by American Association for the Advancement of Science (AAAS)
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  • 102
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    Goal orientation by blindfolded humans after long-distance displacement: possible involvement of a magnetic sense (1980)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1980-10-31
    Description: A wide range of animals are able to orient toward home when subjected to displacement-release experiments. When comparable experiments are performed on blindfolded humans, a similar ability emerges. Such goal-orientation does not result from following the complete journey on a mental map, nor is it influenced by cloud cover. Bar magnets worn on the head do seem to exert an influence.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Baker, R R -- New York, N.Y. -- Science. 1980 Oct 31;210(4469):555-7.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/7423208" target="_blank"〉PubMed〈/a〉
    Keywords: Adult ; Female ; Humans ; Magnetics ; Male ; Orientation/*physiology
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
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  • 103
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    Role of ornithine decarboxylase in cardiac growth and hypertrophy (1980)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1980-11-14
    Description: Inhibition of cardiac ornithine decarboxylase (ODC) by alpha-difluoromethylornithine (DFMO) did not prevent normal cardiac growth in mature rats but attenuated isoproterenol-induced hypertrophy. Hypertrophy caused by triiodothyronine was not prevented by DFMO. There appear to be both ODC-dependent and ODC-independent processes contributing to the subcellular mechanisms associated with growth, which must be considered in the potential laboratory and clinical use of DFMO.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Bartolome, J -- Huguenard, J -- Slotkin, T A -- DA-00006/DA/NIDA NIH HHS/ -- HD-09713/HD/NICHD NIH HHS/ -- New York, N.Y. -- Science. 1980 Nov 14;210(4471):793-4.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/6449079" target="_blank"〉PubMed〈/a〉
    Keywords: Animals ; Carboxy-Lyases/*metabolism ; Cardiomegaly/chemically induced/*metabolism/prevention & control ; Eflornithine ; Heart/*growth & development ; Isoproterenol/antagonists & inhibitors ; Male ; Myocardium/enzymology ; Ornithine/analogs & derivatives/pharmacology ; Ornithine Decarboxylase/*metabolism ; Ornithine Decarboxylase Inhibitors ; Rats ; Triiodothyronine/antagonists & inhibitors
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
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  • 104
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    Sex differences in mathematical ability: fact or artifact? (1980)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1980-12-12
    Description: A substantial sex difference in mathematical reasoning ability (score on the mathematics test of the Scholastic Aptitude Test) in favor of boys was found in a study of 9927 intellectually gifted junior high school students. Our data contradict the hypothesis that differential course-taking accounts for observed sex differences in mathematical ability, but support the hypothesis that these differences are somewhat increased by environmental influences.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Benbow, C P -- Stanley, J C -- New York, N.Y. -- Science. 1980 Dec 12;210(4475):1262-4.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/7434028" target="_blank"〉PubMed〈/a〉
    Keywords: Adolescent ; Environment ; Female ; Humans ; Intelligence ; Logic ; Male ; Mathematics ; *Sex ; Sociology
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
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  • 105
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    Site-specific X-chromosome rearrangements from hybrid dysgenesis in Drosophila melanogaster (1980)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1980-10-01
    Description: When the germ line of Drosophila males is destabilized by a syndrome known as hybrid dysgenesis, X-chromosome rearrangements are found in up to 10 percent of the gametes produced. Some of these aberrations are simple inversions, but many are complex multibreak rearrangements. Furthermore, most of the breakpoints fall into a few highly localized positions on the chromosome. These positions are mostly at points of intercalary heterochromatin and may vary from one strain to the next. the results suggest that they may represent points of insertion of mobile DNA sequences.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Berg, R -- Engels, W R -- Kreber, R A -- GM 07131/GM/NIGMS NIH HHS/ -- GM 22038/GM/NIGMS NIH HHS/ -- New York, N.Y. -- Science. 1980 Oct;210(4468):427-9.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/6776625" target="_blank"〉PubMed〈/a〉
    Keywords: Animals ; Chromosome Inversion ; Chromosome Mapping ; DNA/genetics ; Drosophila melanogaster/*genetics ; Female ; Male ; Meiosis ; Repetitive Sequences, Nucleic Acid ; *Sex Chromosomes ; Translocation, Genetic ; *X Chromosome
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
    Published by American Association for the Advancement of Science (AAAS)
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  • 106
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    Adrenocorticotropic hormone may be transported directly from the pituitary to the brain (1980)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1980-10-31
    Description: Experiments were designed to test the hypothesis that pituitary hormones may be delivered directly to the brain. Concentrations of adrenocorticotropic hormone (ACTH) in the plasma were determined in blood samles obtained simultaneously from the carotid artery, the sagittal sinus, and the jugular vein of three awake sheep. Seizures were induced electrically to stimulate ACTH secretion, and at precise intervals thereafter several simultaneous comparisons were made in each animal. In many of the post-seizure comparisons, the ACTH plasma concentrations within the sagital sinus exceeded those within the carotid artery as well as those within the jugular vein, indicating that this hormone was released from the pituitary and carried directly through capillary beds of brain to the venous blood within the sagittal sinus. The experiment was repeated in one hypophysectomized sheep and, in this animal, ACTH concentration in the plasma was reduced, but that in the sagittal sinus still was elevated after the seizure, an indication that some ACTH (or ACTH-like material) was released from the brain itself.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Bergland, R -- Blume, H -- Hamilton, A -- Monica, P -- Paterson, R -- New York, N.Y. -- Science. 1980 Oct 31;210(4469):541-3.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/6252607" target="_blank"〉PubMed〈/a〉
    Keywords: Adrenocorticotropic Hormone/*blood ; Animals ; Blood-Brain Barrier ; Brain/*blood supply ; Carotid Arteries ; Epilepsy, Tonic-Clonic/blood ; Female ; Hypophysectomy ; Jugular Veins ; Male ; Sheep ; Time Factors
    Print ISSN: 0036-8075
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  • 107
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    Tumor anorexia: a learned food aversion? (1980)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1980-07-18
    Description: Anorexia can occur when a specific diet is associated with a developing illness. The studies reported here show that the decline in food intake which accompanies tumor growth is accompanied by the development of aversions to the specific diet consumed during tumor growth. An immediate elevation in food consumption occurred when a novel diet was introduced. Therefore, the development of learned aversions to the specific diet eaten during tumor growth may be a causal factor in the development of tumor anorexia.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Bernstein, I L -- Sigmundi, R A -- New York, N.Y. -- Science. 1980 Jul 18;209(4454):416-8.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/6930106" target="_blank"〉PubMed〈/a〉
    Keywords: Animals ; Anorexia/*etiology ; Feeding and Eating Disorders/*etiology ; Food Preferences ; Humans ; *Learning ; Male ; Rats ; Sarcoma, Experimental/complications/*physiopathology
    Print ISSN: 0036-8075
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  • 108
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    Abnormality of the X chromosome in human 46,XY female siblings with dysgenetic ovaries (1980)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1980-02-15
    Description: An abnormal extra band was found on the short arm of the X chromosome in a 46,XY female and in her 46,XY female fetal sibling. Despite presence of the intact Y chromosome, there was no evidence of testicular differentiation in either subject. Production of H-Y antigen was suppressed in both subjects. The data suggest that development of the mammalian testis requires a normal function of the X chromosome.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Bernstein, R -- Koo, G C -- Wachtel, S S -- New York, N.Y. -- Science. 1980 Feb 15;207(4432):768-9.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/7352285" target="_blank"〉PubMed〈/a〉
    Keywords: Female ; Gonadal Dysgenesis/*genetics ; Gonadal Dysgenesis, 46,XY/*genetics ; H-Y Antigen/analysis/genetics ; Humans ; Male ; Ovary/abnormalities/embryology ; Sex Chromosome Aberrations/*genetics ; *Sex Chromosomes ; Sex Determination Analysis ; Testis/embryology ; *X Chromosome
    Print ISSN: 0036-8075
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  • 109
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    Plaminogen is synthesized by primary cultures of rat hepatocytes (1980)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1980-07-18
    Description: The accumulation of rat plasminogen in the medium of primary monolayer cultures of adult parenchymal hepatocytes was detected with a quantitative immunological assay. These primary cultures synthetisized and secreted both circulating isozymic forms of plasminogen at rates sufficient to account for the majority of the in vivo plasminogen turnover.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Bohmfalk, J F -- Fuller, G M -- New York, N.Y. -- Science. 1980 Jul 18;209(4454):408-10.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/7384814" target="_blank"〉PubMed〈/a〉
    Keywords: Animals ; Cells, Cultured ; Electrophoresis, Polyacrylamide Gel ; Enzyme-Linked Immunosorbent Assay ; Liver/*metabolism ; Male ; Plasminogen/*biosynthesis ; Rats
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
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  • 110
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    Does malnutrition affect fecundity? A summary of evidence (1980)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1980-05-09
    Description: Moderate chronic malnutrition has only a minor effect on fecundity (reproductive capacity), and the resulting effect on fertility (actural reproduction) is very small. Among the fecundity components examined here in noncontracepting populations, age at menarche and the duration of lactational amenorrhea appear to be the ones most affected by malnutrition. But from neither of those effects can a difference in fertility of more than a few percent be expected between poorly and well-nourished women in developing countries.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Bongaarts, J -- New York, N.Y. -- Science. 1980 May 9;208(4444):564-9.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/7367878" target="_blank"〉PubMed〈/a〉
    Keywords: Abortion, Induced ; Adolescent ; Adult ; Age Factors ; Behavior ; Birth Intervals ; Contraception ; Female ; *Fertility ; Fetal Death/epidemiology ; Humans ; Lactation ; Male ; Marriage ; Menarche ; Menopause ; Middle Aged ; Nutrition Disorders/*physiopathology ; Nutritional Physiological Phenomena ; Ovulation ; Pregnancy ; Spermatogenesis
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
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  • 111
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    Hormone accumulation in a sexually dimorphic motor nucleus of the rat spinal cord (1980)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1980-10-31
    Description: The fifth and sixth lumbar segments of the rat spinal cord were found to contain a sexually dimorphic nucleus, the spinal nucleus of the bulbocavernosus (SNB). The SNB, which contains motoneurons innervating perineal striated muscles in normal male rats, is adiminished or absent in normal females and in males with a genetic mutation rendering them insensitive to androgens. The presence of the nucleus is apparently not dependent on genetic sex, but on the action of androgens. The motoneurons of the adult male SNGH accumulate hormone after systemic injections of radioactive testosterone or dihydrotestosterone, but not estradiol, and the SNB motoneurons accumulate more of the injected androgens than do other motoneurons in the same spinal segments. These results demonstrate a morphological sex difference in hormone-sensitive motoneurons that are probably involved in the sexually dimorphic copulatory behavior of the rat.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Breedlove, S M -- Arnold, A P -- 5-S07/PHS HHS/ -- RR07009-14/RR/NCRR NIH HHS/ -- New York, N.Y. -- Science. 1980 Oct 31;210(4469):564-6.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/7423210" target="_blank"〉PubMed〈/a〉
    Keywords: Animals ; Autoradiography ; Copulation/physiology ; Dihydrotestosterone/*metabolism ; Estradiol/*metabolism ; Female ; Male ; Motor Neurons/*metabolism ; Rats ; Sex ; Spinal Cord/*metabolism ; Testosterone/*metabolism
    Print ISSN: 0036-8075
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  • 112
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    Histamine-mediated delayed permeability response after scald burn inhibited by cimetidine or cold-water treatment (1980)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1980-08-15
    Description: Scald injury to one ear of the hairless mouse induced significant (P 〈 .05) delayed edema formation in remote, uninjured skin. This remote edema formation was completely inhibited by immediate cold-water treatment of the scalded ear. Cold-water treatment significantly reduced histamine loss from the scalded ear, and the edema-inhibiting effect of the treatment could be mimicked by treating the animal prior to injury with the H2-histamine receptor antagonist cimetidine or a drug that causes histamine depletion. These observations suggest (i) that a histamine-mediated, delayed permeability response occurs after thermal injury that causes remote edema formation and (ii) that one mechanism of remote edema inhibition by cold-water treatment is the prevention of histamine release from thermally injured tissues.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Boykin, J V Jr -- Eriksson, E -- Sholley, M M -- Pittman, R N -- New York, N.Y. -- Science. 1980 Aug 15;209(4458):815-7.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/6157189" target="_blank"〉PubMed〈/a〉
    Keywords: Animals ; Burns/complications/physiopathology/*therapy ; Cell Membrane Permeability ; Cimetidine/*pharmacology ; *Cold Temperature ; Edema/etiology/physiopathology ; Guanidines/*pharmacology ; Histamine Release/*drug effects ; Indomethacin/pharmacology ; Male ; Mice ; Receptors, Histamine H2/physiology
    Print ISSN: 0036-8075
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    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
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  • 113
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    A bank for Nobel sperm (1980)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1980-03-21
    Description: 〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Broad, W J -- New York, N.Y. -- Science. 1980 Mar 21;207(4437):1326-7.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/7355292" target="_blank"〉PubMed〈/a〉
    Keywords: Adult ; Female ; Humans ; *Insemination, Artificial ; *Insemination, Artificial, Heterologous ; Male ; *Nobel Prize ; *Spermatozoa ; *Tissue Banks ; Tissue Donors
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
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  • 114
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    Elastase digestion of demembranated sperm flagella (1980)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1980-03-21
    Description: The changes in adenosine triphosphate-reactivated motility resulting from digestion of Triton-demembranated sea urchin sperm flagella by elastase are those expected if the elastic interdoublet linkages between flagellar microtubules are particularly sensitive to digestion by elastase and take part in regulating the amplitude of flagellar bending.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Brokaw, C J -- New York, N.Y. -- Science. 1980 Mar 21;207(4437):1365-7.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/6898364" target="_blank"〉PubMed〈/a〉
    Keywords: Animals ; Flagella/*physiology/ultrastructure ; Male ; Microtubules/physiology ; Movement ; Pancreatic Elastase/metabolism ; Proteins/physiology ; Sea Urchins ; *Sperm Motility ; Trypsin/metabolism
    Print ISSN: 0036-8075
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  • 115
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    Excitatory and inhibitory effects of serotonin on sensorimotor reactivity measured with acoustic startle (1980)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1980-07-25
    Description: Serotonin infused into the lateral ventricle in rats produced a dose-dependent depression of the acoustic startle reflex. When infused onto the spinal cord, serotonin produced a dose-dependent increase in startle. Thus the same neurotransmitter can modulate the same behavior in opposite ways, depending on which part of the central nervous system is involved.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Davis, M -- Strachan, D I -- Kass, E -- New York, N.Y. -- Science. 1980 Jul 25;209(4455):521-3.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/7394520" target="_blank"〉PubMed〈/a〉
    Keywords: Animals ; Dose-Response Relationship, Drug ; Kinetics ; Male ; Rats ; Reflex, Acoustic/*drug effects ; Reflex, Startle/*drug effects ; Serotonin/*pharmacology
    Print ISSN: 0036-8075
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  • 116
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    Origin of chi46,XX/46,XY chimerism in a human true hermaphrodite (1980)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1980-01-18
    Description: Using chromosome heteromorphisms and blood cell types as genetic markers, we demonstrated chimerism in a chi46,XX/46,XY true hermaphrodite. The pattern of inheritance of the chromosome heteromorphisms indicates that this individual was probably conceived by the fertilization, by two different spermatozoa, of an ovum and the second meiotic division polar body derived from the ovum and subsequent fusion of the two zygotes. This conclusion is based on the identification of the same maternal chromosomes 13, 16, and 21 in both the 46,XX and 46,XY cells of the patient. In the two cell lines of the chimera, chromosomal markers showed different paternal No. 9 chromosomes and sex chromosomes, as well as the same paternal chromosome 22.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Dewald, G -- Haymond, M W -- Spurbeck, J L -- Moore, S B -- New York, N.Y. -- Science. 1980 Jan 18;207(4428):321-3.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/7350665" target="_blank"〉PubMed〈/a〉
    Keywords: *Chimera ; Disorders of Sex Development/blood/*genetics/pathology ; Fertilization ; Functional Laterality ; Humans ; Infant, Newborn ; Kidd Blood-Group System/genetics ; Male ; Meiosis ; Sex Chromosome Aberrations
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    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
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  • 117
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    Sparing of the brain in neonatal undernutrition: amino acid transport and incorporation into brain and muscle (1980)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1980-02-22
    Description: Rates of tyrosine and lysine transport and incorporation into protein were measured in control and undernourished weanling rats. Undernutrition was induced by feeding lactating dams a low protein diet (12 percent casein) from birth to day 21. At weaning, body and brain weights of undernourished rats were 50 percent and 88 percent, respectively, of control values. Lysine and tyrosine transport rates into skeletal muscle were reduced by over 75 percent, more than twice the reduction seen in brain. Rates of amino acid incorporation into muscle protein were reduced by approximately 50 percent; the change in rate of incorporation into brain protein was not statistically significant. These data indicate that, in spite of marked retardation of amino acid transport into brain, the brain seems fully capable of maintaining normal rates of protein synthesis.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Freedman, L S -- Samuels, S -- Fish, I -- Schwartz, S A -- Lange, B -- Katz, M -- Morgano, L -- New York, N.Y. -- Science. 1980 Feb 22;207(4433):902-4.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/6766565" target="_blank"〉PubMed〈/a〉
    Keywords: Amino Acids/*metabolism ; Animals ; Animals, Newborn/metabolism ; Biological Transport ; Body Weight ; Brain/growth & development/*metabolism ; Disease Models, Animal ; Female ; Lactation ; Male ; Muscles/*metabolism ; Pregnancy ; Protein-Energy Malnutrition/*metabolism ; Rats
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    Fasting associated with decrease in hypothalamic beta-endorphin (1980)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1980-12-12
    Description: In rats that were fasted for 2 to 3 days there was a decline in hypothalamic, but not pituitary, beta-endorphin. There was no change in pituitary or hypothalamic adrenocorticotropin content as a result of fasting. Endogenous opiates may be involved in physiological adaptation to fasting.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Gambert, S R -- Garthwaite, T L -- Pontzer, C H -- Hagen, T C -- New York, N.Y. -- Science. 1980 Dec 12;210(4475):1271-2.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/6254156" target="_blank"〉PubMed〈/a〉
    Keywords: Adrenocorticotropic Hormone/metabolism ; Animals ; Endorphins/*metabolism ; *Fasting ; Hypothalamus/*metabolism ; Male ; Pituitary Gland/metabolism ; Rats ; Time Factors
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    Ala-Gly- and Val-Asp-[Arg8]-vasopressin: bovine storage forms of arginine vasopressin with natriuretic activity (1980)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1980-02-22
    Description: Extracts of fresh-frozen bovine neurohypophysis were purified by chromatographic techniques to isolate and characterize the components that produce natriuresis in nondiuretic dogs. Two compounds with natiuretic properties similar to those of synthetic arginine vasopressin accounted for most of the natriuretic activity and appeared to be the prevalent vasopressin-like molecules in the extract. These peptides were Ala-Gly-[Arg8]-vasopressin and Val-Asp-[Arg8]-vasopressin; the natriuretic potency of each appeared to be similar to synthetic arginine vasopressin and could be observed with doses in the range of 50 picomoles. In the dog the most conspicuous difference between synthetic arginine vasopressin and the new vasopressin peptides was the smaller pressor responses to natriuretic doses of the new compounds.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Gitelman, H J -- Klapper, D G -- Alderman, F R -- Blythe, W B -- New York, N.Y. -- Science. 1980 Feb 22;207(4433):893-6.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/7355269" target="_blank"〉PubMed〈/a〉
    Keywords: Amino Acid Sequence ; Animals ; Arginine Vasopressin/analogs & derivatives/*metabolism/pharmacology ; Biological Assay ; Blood Pressure/drug effects ; Cattle ; Dogs ; Male ; Natriuresis/*drug effects ; Pituitary Gland, Posterior/*metabolism ; Protein Precursors/metabolism ; Structure-Activity Relationship
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    Privacy, confidentiality, and the use of medical records in research (1980)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1980-01-11
    Description: 〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Gordis, L -- Gold, E -- New York, N.Y. -- Science. 1980 Jan 11;207(4427):153-6.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/7350648" target="_blank"〉PubMed〈/a〉
    Keywords: Cardiovascular Diseases/etiology ; *Confidentiality ; Diethylstilbestrol/adverse effects ; Disease Outbreaks/etiology ; *Epidemiologic Methods ; Female ; Humans ; Informed Consent ; Male ; *Medical Records ; Neoplasms/etiology
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  • 121
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    Classical conditioning: induction of luteinizing hormone and testosterone secretion in anticipation of sexual activity (1980)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1980-11-28
    Description: A classical conditioning paradigm was used to demonstrate that male rats can learn to secrete luteinizing hormone and testosterone in anticipation of sexual activity. Sexually naive males were exposed to a neutral stimulus and then to a sexually receptive female once daily. After exposure to the paired stimuli for 14 trials, the neutral stimulus was as effective as the female in triggering luteinizing hormone and testosterone secretion. These findings provide two novel perspectives on the control of reproductive hormone secretion in male rats: (i) environmental cues, which males learn to associate with sexual activity, induce the secretion of hormones that regulate pituitary-testis function, and (ii) classical conditioning may be used as a noninvasive method to evoke functional alterations in the secretion of luteinizing hormone and presumably the neuroendocrine pathways that mediate its release.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Graham, J M -- Desjardins, C -- HD-13470/HD/NICHD NIH HHS/ -- New York, N.Y. -- Science. 1980 Nov 28;210(4473):1039-41.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/7434016" target="_blank"〉PubMed〈/a〉
    Keywords: Animals ; Arousal/physiology ; Conditioning, Classical/*physiology ; Humans ; Luteinizing Hormone/*secretion ; Male ; Pituitary Gland, Anterior/secretion ; Rats ; Sexual Behavior, Animal/*physiology ; Testis/secretion ; Testosterone/*secretion ; Time Factors
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    Brainstem catecholamine neurons are target sites for sex steroid hormones (1980)
    American Association for the Advancement of Science (AAAS)
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    Publication Date: 1980-03-21
    Description: Sex steroid hormones and catecholamines have physiological interactions in the brain. By the combined use of autoradiography and fluorescence histochemistry, steroid hormone target sites and catecholamine neurons were visualized simultaneously in the same tissue preparation. By this dual localization method, [3H]estradiol and [3H]dihydrotestosterone target sites were identified in nuclei of many catecholamine cell bodies in the brainstem, and catecholamine nerve terminals were observed near certain steroid hormone target neurons. These results suggest close anatomical interrelations between steroid hormone sites of action and catecholamine sites of production and action in the brain.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Heritage, A S -- Stumpf, W E -- Sar, M -- Grant, L D -- New York, N.Y. -- Science. 1980 Mar 21;207(4437):1377-9.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/7355296" target="_blank"〉PubMed〈/a〉
    Keywords: Adrenalectomy ; Animals ; Brain/cytology/*metabolism ; Castration ; Catecholamines/*metabolism ; Diencephalon/metabolism ; Dihydrotestosterone/*metabolism ; Estradiol/*metabolism ; Female ; Male ; Mesencephalon/metabolism ; Microscopy, Fluorescence ; Rats
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    Feeding increases dopamine metabolism in the rat brain (1980)
    American Association for the Advancement of Science (AAAS)
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    Publication Date: 1980-06-06
    Description: Feeding induced by food deprivation is accompanied by an increased production of the dopamine metabolite 3,4-dihydroxyphenylacetic acid in the brains of rats. This neurochemical change occurs in the nucleus accumbens, the posterior hypothalamus, and the amygdala but not in other dopaminergic nerve terminal fields such as the corpus striatum. These results indicate that the release of dopamine from particular groups of central neurons is increased during feeding and suggest that anatomically distinct subgroups of central dopaminergic neurons serve different roles in the regulation of food intake.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Heffner, T G -- Hartman, J A -- Seiden, L S -- New York, N.Y. -- Science. 1980 Jun 6;208(4448):1168-70.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/7375926" target="_blank"〉PubMed〈/a〉
    Keywords: 3,4-Dihydroxyphenylacetic Acid/metabolism ; Amygdala/metabolism ; Animals ; Brain/*metabolism ; Dopamine/*metabolism ; *Eating ; Food Deprivation ; Hypothalamus/metabolism ; Male ; Nucleus Accumbens/metabolism ; Putamen/metabolism ; Rats ; Satiation/*physiology
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    Purinergic receptors: photoaffinity analog of adenosine triphosphate is a specific adenosine triphosphate antagonist (1980)
    American Association for the Advancement of Science (AAAS)
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    Publication Date: 1980-06-13
    Description: Arylazido aminopropionyl adenosine triphosphate (ANAPP3), a photoaffinity label, antagonized specifically adenine nucleotide-induced contractions of the guinea pig vas deferens. Irradiation of tissues with visible light in the presence of ANAPP3 resulted in an irreversible antagonism, which was prevented when adenosine triphosphate was present. In the absence of light, the antagonism was reversible and may have resulted from an autoinhibition phenomenon. Responses to acetylcholine, histamine, norepinephrine, and potassium chloride were not affected by ANAPP3.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Hogaboom, G K -- O'Donnell, J P -- Fedan, J S -- New York, N.Y. -- Science. 1980 Jun 13;208(4449):1273-6.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/6103581" target="_blank"〉PubMed〈/a〉
    Keywords: Adenine Nucleotides/antagonists & inhibitors ; Adenosine Triphosphate/*analogs & derivatives/*antagonists & ; inhibitors/pharmacology ; Affinity Labels ; Animals ; *Azides ; Guinea Pigs ; In Vitro Techniques ; Light ; Male ; Muscle Contraction/drug effects ; Muscle, Smooth/drug effects ; Neurotransmitter Agents/antagonists & inhibitors ; Potassium Chloride/antagonists & inhibitors ; Receptors, Neurotransmitter/drug effects ; Vas Deferens
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    Rand issues final alcoholism report (1980)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1980-02-22
    Description: 〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Holden, C -- New York, N.Y. -- Science. 1980 Feb 22;207(4433):855-6.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/7355266" target="_blank"〉PubMed〈/a〉
    Keywords: Adult ; Alcohol Drinking ; Alcoholism/*physiopathology/prevention & control/therapy ; Follow-Up Studies ; Humans ; Male
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    Motile flagellum with a "3 + 0" ultrastructure (1980)
    American Association for the Advancement of Science (AAAS)
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    Publication Date: 1980-03-28
    Description: The male gamete of the parasitic protozoan Diplauxis hatti has a flagellum consisting of three doublet microtubules. This flagellum exhibits a helicoidal waveform in which bends propagate toward the tip with a frequency of about 1.5 hertz. It is the simplest motile eukaryotic flagellum yet described.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Prensier, G -- Vivier, E -- Goldstein, S -- Schrevel, J -- New York, N.Y. -- Science. 1980 Mar 28;207(4438):1493-4.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/7189065" target="_blank"〉PubMed〈/a〉
    Keywords: Animals ; Eukaryota/*ultrastructure ; Flagella/*physiology/ultrastructure ; Male ; Microtubules/ultrastructure ; Motion ; Spermatozoa/ultrastructure
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    Faster cholinergic REM sleep induction in euthymic patients with primary affective illness (1980)
    American Association for the Advancement of Science (AAAS)
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    Publication Date: 1980-04-11
    Description: Arecoline, a cholinergic muscarinic receptor agonist, induced rapid eye movement sleep significantly more rapidly in patients with primary affective illness in remission than in normal control subjects matched for age and sex. These results, and others, suggest that patients with primary affective illness may have a supersensitive cholinergic system both when they are ill and when their symptoms are in clinical remission.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Sitaram, N -- Nurnberger, J I Jr -- Gershon, E S -- Gillin, J C -- New York, N.Y. -- Science. 1980 Apr 11;208(4440):200-2.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/7361118" target="_blank"〉PubMed〈/a〉
    Keywords: Adult ; Affective Symptoms/drug therapy/*physiopathology ; Arecoline/*pharmacology ; Female ; Humans ; Injections, Intravenous ; Male ; Sleep Wake Disorders/physiopathology ; Sleep, REM/*drug effects
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    Anticonvulsants specific for petit mal antagonize epileptogenic effect of leucine enkephalin (1980)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1980-11-28
    Description: The anticonvulsants ethosuximide, sodium valproate, and trimethadione that are specific for petit mal epilepsy abolished in rats the electrical seizure activity and behavioral abnormalities produced by leucine enkephalin, whereas phenobarbital and phenytoin had no effect. The dose-response curve for naloxone against seizure activity induced by leucine enkephalin was the same as that in gamma-hydroxybutyrate-induced petit mal. These data indicate that the epileptic properties of leucine enkephalin are petit mal-like and raise the possibility of involvement of enkephalinergic systems in. The dose-response curve for naloxone against seizure activity induced by leucine enkephalin was the same as that in gamma-hydroxybutyrate-induced petit mal. These data indicate that the epileptic properties of leucine enkephalin are petit mal-like and raise the possibility of involvement of enkephalinergic systems in petit mal epilepsy.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Snead, O C 3rd -- Bearden, L J -- 1K07 NS 00 484-01/NS/NINDS NIH HHS/ -- New York, N.Y. -- Science. 1980 Nov 28;210(4473):1031-3.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/6254150" target="_blank"〉PubMed〈/a〉
    Keywords: Animals ; Anticonvulsants/*pharmacology ; Disease Models, Animal ; Endorphins/*antagonists & inhibitors ; Enkephalins/*antagonists & inhibitors ; Epilepsy, Absence/drug therapy/*physiopathology ; Ethosuximide/pharmacology ; Male ; Rats ; Receptors, Opioid/drug effects ; Seizures/*prevention & control ; Trimethadione/pharmacology ; Valproic Acid/pharmacology
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    Evidence for a vesicular transport mechanism in hepatocytes for biliary secretion of immunoglobulin A (1980)
    American Association for the Advancement of Science (AAAS)
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    Publication Date: 1980-06-13
    Description: Quantitative electron microscopic autoradiography and diaminobenzidine cytochemistry provide evidence for an uptake and vesicular transport mechanism for iodine-125-labeled immunoglobulin A from plasma to bile by hepatocytes in vivo. The data confirm the existence of a hepatobiliary pathway for secretion of immunoglobulin A into the intestine and are consistent with a vesicular transport mechanism for biliary proteins within liver parenchymal cells.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Renston, R H -- Jones, A L -- Christiansen, W D -- Hradek, G T -- Underdown, B J -- New York, N.Y. -- Science. 1980 Jun 13;208(4449):1276-8.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/7375938" target="_blank"〉PubMed〈/a〉
    Keywords: Animals ; Autoradiography ; Bile/*immunology ; Biological Transport ; Cell Membrane/metabolism ; Cytoplasm/metabolism ; Immunoglobulin A/*metabolism ; Immunoglobulin A, Secretory/*metabolism ; Liver/immunology/*secretion ; Male ; Organoids/metabolism ; Rats ; Secretory Component/metabolism
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    Antireproductive effects of a potent gonadotropin-releasing hormone antagonist in the male rat (1980)
    American Association for the Advancement of Science (AAAS)
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    Publication Date: 1980-10-03
    Description: Administration of a potent antagonist of gondadotropin-releasing hormone (GnRH) antagonist [Ac-dehydro-Pro1, pCl-D-Phe2, D-Trp3,6]-N alpha-MeLeu7-GnRH to adult male rats for 2 weeks resulted in decreased testosterone production and sexual organ weights and in disrupted spermatogenesis. The results demonstrate the essential role of gonadotropin-releasing hormone in the maintenance of reproductive functions and have implications for the regulation of male fertility.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Rivier, C -- Rivier, J -- Vale, W -- HD09690/HD/NICHD NIH HHS/ -- RFP CD-78-5/FP/OFP OPHS HHS/ -- New York, N.Y. -- Science. 1980 Oct 3;210(4465):93-5.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/6774418" target="_blank"〉PubMed〈/a〉
    Keywords: Animals ; Chorionic Gonadotropin/pharmacology ; Drug Interactions ; Follicle Stimulating Hormone/blood ; *Gonadotropin-Releasing Hormone/*analogs & derivatives ; Infertility, Male/*chemically induced ; Luteinizing Hormone/blood ; Male ; Organ Size ; Pituitary Hormone Release Inhibiting Hormones/*pharmacology ; Pituitary Hormone-Releasing Hormones/*antagonists & inhibitors/physiology ; Prostate/drug effects ; Rats ; Seminal Vesicles/drug effects ; Spermatogenesis/drug effects ; Testis/drug effects ; Testosterone/blood
    Print ISSN: 0036-8075
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    Magnesium deficiency produces spasms of coronary arteries: relationship to etiology of sudden death ischemic heart disease (1980)
    American Association for the Advancement of Science (AAAS)
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    Publication Date: 1980-04-11
    Description: Isolated coronary arteries from dogs were incubated in Krebs-Ringer bicarbonate isolation and exposed to normal, high, and low concentrations of magnesium in the medium. Sudden withdrawal of magnesium from the medium increased whereas high concentrations of magnesium decreased the basal tension of the arteries. The absence of magnesium in the medium significantly potentiated the contractile responses of both small and large coronary arteries to norepinephrine, acetylcholine, serotonin, angiotensin, and potassium. These data support the hypothesis that magnesium deficiency, associated with sudden death ischemic heart disease, produces coronary arterial spasm.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Turlapaty, P D -- Altura, B M -- New York, N.Y. -- Science. 1980 Apr 11;208(4440):198-200.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/7361117" target="_blank"〉PubMed〈/a〉
    Keywords: Acetylcholine/pharmacology ; Angiotensin II/pharmacology ; Animals ; Calcium/metabolism ; Coronary Disease/*etiology ; Coronary Vessels/drug effects/physiopathology ; Death, Sudden/etiology ; Dogs ; Female ; Magnesium/metabolism/pharmacology ; Magnesium Deficiency/*complications/physiopathology ; Male ; Norepinephrine/pharmacology ; Potassium Chloride/pharmacology ; Serotonin/pharmacology ; Spasm/etiology ; Vasomotor System/drug effects
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    Carboxyhemoglobin levels in an unstable hemoglobin disorder (Hb Zurich): effect on phenotypic expression (1980)
    American Association for the Advancement of Science (AAAS)
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    Publication Date: 1980-07-18
    Description: The affinity of Hb Zurich for carbon monoxide is approximately 65 times that of normal hemoglobin. The carboxyhemoglobin content in serum from individuals with Hb Zurich ranged from 3.9 to 6.7 percent in nine nonsmokers and from 9.8 to 19.7 percent in six smokers. Rates of hemolysis and hemoglobin denaturation were less in smokers than in nonsmokers, effects that may be secondary to the stabilization of Hb Zurich by carbon monoxide.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Zinkham, W H -- Houtchens, R A -- Caughey, W S -- New York, N.Y. -- Science. 1980 Jul 18;209(4454):406-8.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/7384813" target="_blank"〉PubMed〈/a〉
    Keywords: Adolescent ; Adult ; Carboxyhemoglobin/*analysis/genetics ; Child ; Female ; Hematocrit ; Hemoglobins/*analysis ; Hemoglobins, Abnormal/*analysis/genetics ; Humans ; Male ; Middle Aged ; Phenotype ; Smoking
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    Two coronaviruses isolated from central nervous system tissue of two multiple sclerosis patients (1980)
    American Association for the Advancement of Science (AAAS)
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    Publication Date: 1980-08-22
    Description: Two coronaviruses were isolated from brain material obtained at autopsy from two multiple sclerosis patients. The viruses were neutralized by serum and spinal fluid from these patients. Although most of the population have antibody to these virus isolates, multiple sclerosis patients have slightly higher concentrations of serum antibody than controls. The results suggest that coronaviruses should be considered as one additional virus with a potential implication in the etiology of multiple sclerosis.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Burks, J S -- DeVald, B L -- Jankovsky, L D -- Gerdes, J C -- New York, N.Y. -- Science. 1980 Aug 22;209(4459):933-4.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/7403860" target="_blank"〉PubMed〈/a〉
    Keywords: Aged ; Animals ; Antibodies, Viral/analysis ; Brain/*microbiology ; Cells, Cultured ; Coronaviridae/immunology/*isolation & purification ; Female ; Freezing ; Humans ; Male ; Mice ; Middle Aged ; Multiple Sclerosis/*microbiology/pathology
    Print ISSN: 0036-8075
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    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
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    Insulin receptors in hepatocytes: postreceptor events mediate down regulation (1980)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1980-11-28
    Description: Down regulation of the insulin receptor of primary cultures of rat hepatocytes occurs in the presence of insulin and several agents with insulin-like activity, which act through or distal to the insulin receptor. These findings indicate that the interaction of insulin with its specific binding site is not in itself sufficient to down-regulate this receptor and that one or more steps subsequent to this interaction are necessary. Thus, down regulation may be a complex biological response to insulin, and if a cell were resistant to this effect of insulin, our data may explain how target cells from a patient or animal can have a normal number of receptors in the presence of increased concentrations of circulating insulin.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Caro, J F -- Amatruda, J M -- AM 00366/AM/NIADDK NIH HHS/ -- AM 20948/AM/NIADDK NIH HHS/ -- New York, N.Y. -- Science. 1980 Nov 28;210(4473):1029-31.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/7001632" target="_blank"〉PubMed〈/a〉
    Keywords: Animals ; Insulin/metabolism ; Kinetics ; Liver/*metabolism ; Male ; Peroxides/pharmacology ; Rats ; Receptor, Insulin/drug effects/immunology/*metabolism ; Spermine/pharmacology ; Vitamin K/pharmacology
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  • 135
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    Subcellular origin of cholinergic transmitter release from mouse brain (1980)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1980-11-07
    Description: Samples of minced mouse forebrain were treated in a way that resulted in a high ratio of false cholinergic transmitter (acetylhomocholine) to true transmitter (acetylcholine) in a synaptic vesicle fraction, and a low ratio of false to true transmitter in the nerve terminal cytoplasm. The spontaneous release of cholinergic transmitters from this minced tissue occurred independently of calcium and had a ratio of false to true transmitter similar to that of the cytoplasm, whereas the evoked transmitter release required calcium and had a ratio of false to true transmitter similar to that of the vesicular fraction.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Carroll, P T -- Aspry, J M -- New York, N.Y. -- Science. 1980 Nov 7;210(4470):641-2.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/7433989" target="_blank"〉PubMed〈/a〉
    Keywords: Acetylcholine/analogs & derivatives/*metabolism ; Animals ; Brain/*metabolism ; Calcium/physiology ; Cytoplasm/metabolism ; Exocytosis/drug effects ; Lithium/pharmacology ; Magnesium/physiology ; Male ; Mice ; Potassium/pharmacology ; Synaptic Vesicles/metabolism
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  • 136
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    Identification of mosquitoes of Anopheles gambiae species complex A and B by analysis of cuticular components (1980)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1980-03-07
    Description: Two important vectors of malaria in Africa, Anopheles gambiae and Anopheles arabiensis (Diptera: Culicidae), often occur sympatrically and cannot be distinguished morphologically. A chemical method was developed to identify individual laboratory-reared adult males or females of either species by extraction and analysis of cuticular components with gas chromatography. Statistically significant differences were seen between species when selected pairs of peaks were compared.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Carlson, D A -- Service, M W -- New York, N.Y. -- Science. 1980 Mar 7;207(4435):1089-91.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/7355276" target="_blank"〉PubMed〈/a〉
    Keywords: Animals ; Anopheles/analysis/*classification ; Chromatography, Gas ; Female ; Lipids/analysis ; Male ; Paraffin/analysis ; Sex Factors ; Skin/analysis ; Species Specificity
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  • 137
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    Recall (versus recognition) of taste and immunization against aversive taste anticipations based on illness (1980)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1980-08-15
    Description: Two experiments show that, after taste-aversion conditioning, rats can use external retrieval cues to recall or anticipate the aversive taste solution and avoid its location without making contact with the flavor. They also show that the rat's avoidance of a conditioned aversive taste and its consumption of the aversive flavored solution can be attenuated by giving it prior runway training in which taste reward is given inconsistently on a partial reinforcement schedule.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Chen, J S -- Amsel, A -- New York, N.Y. -- Science. 1980 Aug 15;209(4458):831-3.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/7403850" target="_blank"〉PubMed〈/a〉
    Keywords: Animals ; Avoidance Learning/*physiology ; Conditioning (Psychology) ; Extinction, Psychological ; Female ; Lithium ; Male ; Memory/*physiology ; Mental Recall/*physiology ; Rats ; Reinforcement (Psychology) ; Sodium Chloride ; Taste/*physiology ; Time Factors
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  • 138
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    Angiotoxicity of oxygenated sterols and possible precursors (1980)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1980-02-08
    Description: Cell death, inflammation, and repair in rabbits' aortas and pulmonary arteries were observed at 3-, 7-, and 10-day periods after the intravenous injection of oxygenated sterols. Thus, oxygenated sterols, not cholesterol, may play the primary role in arterial wall injury and lesion development.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Imai, H -- Werthessen, N T -- Subramanyam, V -- LeQuesne, P W -- Soloway, A H -- Kanisawa, M -- New York, N.Y. -- Science. 1980 Feb 8;207(4431):651-3.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/7352277" target="_blank"〉PubMed〈/a〉
    Keywords: Animals ; Aorta/drug effects ; Blood Vessels/*drug effects/pathology ; Cholesterol/*analogs & derivatives/toxicity ; Epoxy Compounds/*toxicity ; Ethers, Cyclic/*toxicity ; Female ; Hydroxycholesterols/toxicity ; Lanosterol/analogs & derivatives/toxicity ; Male ; Necrosis ; Oxidation-Reduction ; Pulmonary Artery/drug effects ; Rabbits ; Structure-Activity Relationship
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  • 139
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    Medial nucleus of the amygdala mediates chemosensory control of male hamster sexual behavior (1980)
    American Association for the Advancement of Science (AAAS)
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    Publication Date: 1980-10-31
    Description: Bilateral lesions restricted to the medial nucleus of the amygdala eliminate mating behavior in the male hamster and severely diminish the male's sniffing and licking investigation of the female hamster's anogenital region. The results suggest that olfactory and vomeronasal sensory information critical to male mating behavior is processed in the medial nucleus, which is an androgen-binding brain area. Thus the medial nucleus may act as a relay through which chemosensory information influences activity in the medial preoptic-anterior hypothalamic junction and the bed nucleus of the stria terminals, areas important in the mediation of male sexual behavior.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Lehman, M N -- Winans, S S -- Powers, J B -- 5 T32/PHS HHS/ -- MH14279-05/MH/NIMH NIH HHS/ -- NS 14071/NS/NINDS NIH HHS/ -- New York, N.Y. -- Science. 1980 Oct 31;210(4469):557-60.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/7423209" target="_blank"〉PubMed〈/a〉
    Keywords: Amygdala/cytology/*physiology ; Animals ; Chemoreceptor Cells/physiology ; Copulation/physiology ; Cricetinae ; Functional Laterality ; Male ; Sexual Behavior, Animal/*physiology ; Smell/physiology ; Testosterone/physiology
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  • 140
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    beta-Adrenergic regulation of alpha 2-adrenergic receptors in the central nervous system (1980)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1980-02-08
    Description: Incubation of rat cerebral cortical slices with the beta-adrenergic agonist isoproterenol causes an increase in alpha 2-adrenergic receptor binding in addition to a decrease in beta-adrenergic receptor binding. The effects are rapid and reversible, show a parallel time course, and are blocked by sotalol, a beta-adrenergic receptor antagonist. The beta-mediated regulation of alpha 2-receptor sensitivity at brain norepinephrine synapses may be a mechanism for the homeostatic control of central noradrenergic activity.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Maggi, A -- U'Prichard, D C -- Enna, S J -- New York, N.Y. -- Science. 1980 Feb 8;207(4431):645-7.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/6101510" target="_blank"〉PubMed〈/a〉
    Keywords: Adrenergic alpha-Agonists/pharmacology ; Animals ; Brain/*drug effects/metabolism ; Clonidine/analogs & derivatives/metabolism ; Dihydroalprenolol/metabolism ; In Vitro Techniques ; Isoproterenol/antagonists & inhibitors/*pharmacology ; Male ; Rats ; Receptors, Adrenergic/*drug effects ; Receptors, Adrenergic, alpha/*drug effects ; Receptors, Adrenergic, beta/*drug effects/metabolism ; Sotalol/pharmacology
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  • 141
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    Opioid and nonopioid mechanisms of stress analgesia (1980)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1980-05-09
    Description: Inescapable foot shock in rats caused profound analgesia that was antagonized by naloxone or dexamethasone when shock was delivered intermittently for 30 minutes, but not when it was delivered continuously for 3 minutes. Thus, depending only on its temporal characteristics, foot-shock stress appears to activate opioid or nonopioid analgesia mechanisms. Certain forms of stress may act as natural inputs to an endogenous opiate analgesia system.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Lewis, J W -- Cannon, J T -- Liebeskind, J C -- New York, N.Y. -- Science. 1980 May 9;208(4444):623-5.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/7367889" target="_blank"〉PubMed〈/a〉
    Keywords: *Analgesia ; Animals ; Dexamethasone/*pharmacology ; Electroshock ; Endorphins/*physiology ; Male ; Naloxone/pharmacology ; Pain/*physiopathology ; Pituitary Gland/physiology ; Rats ; Stress, Physiological/*physiopathology ; Time Factors
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  • 142
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    Osteoporosis: new help for thinning bones (1980)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1980-02-08
    Description: 〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Marx, J L -- New York, N.Y. -- Science. 1980 Feb 8;207(4431):628-30.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/7352275" target="_blank"〉PubMed〈/a〉
    Keywords: Aging ; Bone Resorption ; Calcitonin/therapeutic use ; Calcium/*metabolism ; Dihydroxycholecalciferols/therapeutic use ; Estrogens/therapeutic use ; Female ; Humans ; Male ; Menopause ; Osteoporosis/drug therapy/*physiopathology/prevention & control ; Parathyroid Hormone/physiology
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  • 143
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    Opiate receptor function may be modulated through an oxidation-reduction mechanism (1980)
    American Association for the Advancement of Science (AAAS)
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    Publication Date: 1980-06-06
    Description: Cupric ion, a thiol oxidant, caused naloxone-reversible analgesia when injected intracerebroventricularly in mice; its potency was close to that of morphine. Dithiothreitol, a thiol reductant, reversed the analgesia induced by cupric ion and antagonized analgesia induced by morphine. Oxidized dithiothreitol had no effect. These findings, together with evidence for redox modification of opiate receptor binding in vitro, suggest that a mechanism of oxidation-reduction of thiols may modulate opiate receptor function.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Marzullo, G -- Hine, B -- New York, N.Y. -- Science. 1980 Jun 6;208(4448):1171-3.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/6246583" target="_blank"〉PubMed〈/a〉
    Keywords: Animals ; Brain/*physiology ; Copper/antagonists & inhibitors/*pharmacology ; Dithiothreitol/pharmacology ; Male ; Mice ; Naloxone/pharmacology ; Oxidation-Reduction ; Pain/*physiopathology ; Rats ; Receptors, Opioid/drug effects/*physiology ; Sulfhydryl Compounds/pharmacology ; Zinc/pharmacology
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  • 144
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    Associative learning in premature hydranencephalic and normal twins (1980)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1980-11-28
    Description: A hydranencephalic infant lacking cerebral hemispheres and a normal twin were tested for associative learning. After repeated trials in which two stimuli were temporally paired, test trials were given in which the second stimulus was omitted. Cardiac orienting responses to stimulus omission indicated that learning had taken place in both infants.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Tuber, D S -- Berntson, G G -- Bachman, D S -- Allen, J N -- New York, N.Y. -- Science. 1980 Nov 28;210(4473):1035-7.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/7192015" target="_blank"〉PubMed〈/a〉
    Keywords: Anencephaly/*physiopathology ; Association/*physiology ; Behavior/physiology ; Brain/physiology ; Brain Stem/physiology ; Female ; Heart Rate ; Humans ; Hydranencephaly/*physiopathology ; Infant ; Infant, Newborn ; Infant, Premature/*psychology ; Male ; Pregnancy ; Twins, Dizygotic
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  • 145
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    Cigarette smoking associated with sleep difficulty (1980)
    American Association for the Advancement of Science (AAAS)
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    Publication Date: 1980-02-01
    Description: A group of 50 smokers experienced greater sleep difficulty than a group of 50 nonsmokers matched by age and sex. The two groups did not differ in personality patterns or drug consumption. Also, sleep patterns significantly improved in a group of eight chronic smokers when they abstained from cigarette smoking. These findings are consistent with reports on the stimulant effects of nicotine.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Soldatos, C R -- Kales, J D -- Scharf, M B -- Bixler, E O -- Kales, A -- New York, N.Y. -- Science. 1980 Feb 1;207(4430):551-3.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/7352268" target="_blank"〉PubMed〈/a〉
    Keywords: Adult ; Coffee/adverse effects ; Female ; Humans ; Male ; Sleep Stages ; Sleep Wake Disorders/*etiology ; Smoking/*complications ; Substance Withdrawal Syndrome/physiopathology
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  • 146
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    Deficient natural killer cell activity in x-linked lymphoproliferative syndrome (1980)
    American Association for the Advancement of Science (AAAS)
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    Publication Date: 1980-10-31
    Description: The activity of natural killer cells was found to be deficient in 10 of 12 males with X-linked lymphoproliferative syndrome, a life-threatening proliferation of lymphocytes after infection by Epstein-Barr virus. The activity levels of natural killer cells from affected males were increased after treatment with interferon in vitro, but normal levels of killing were not obtained. Deficient activity of killer cells in individuals with immunodeficiency and chronic infection by Epstein-Barr virus may contribute to the development of lymphoproliferative disorders.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Sullivan, J L -- Byron, K S -- Brewster, F E -- Purtilo, D T -- CA 23561-01/CA/NCI NIH HHS/ -- New York, N.Y. -- Science. 1980 Oct 31;210(4469):543-5.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/6158759" target="_blank"〉PubMed〈/a〉
    Keywords: Adolescent ; Adult ; Child ; Child, Preschool ; Cytotoxicity, Immunologic ; Female ; Humans ; *Immunity, Innate ; Immunologic Deficiency Syndromes/*genetics ; Infectious Mononucleosis/immunology ; Interferons/pharmacology ; Killer Cells, Natural/*immunology ; Lymphoproliferative Disorders/genetics/*immunology ; Male ; X Chromosome
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  • 147
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    Sexual characteristics of adult female mice are correlated with their blood testosterone levels during prenatal development (1980)
    American Association for the Advancement of Science (AAAS)
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    Publication Date: 1980-05-09
    Description: Mice produce litters containing many pups, and the female fetuses that develop between male fetuses have significantly higher concentrations of the male sex steroid testosterone in both their blood and amniotic fluid than do females that develop between other female fetuses. These two types of females differ during later life in many sexually related characteristics. Thus, individual variation in sexual characteristics of adult female mice may be traceable to differential exposure to testosterone during prenatal development because of intrauterine proximity to male fetuses.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉vom Saal, F S -- Bronson, F H -- New York, N.Y. -- Science. 1980 May 9;208(4444):597-9.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/7367881" target="_blank"〉PubMed〈/a〉
    Keywords: Age Factors ; Amniotic Fluid/*metabolism ; Animals ; Estradiol/blood ; Estrus ; Female ; Fetal Blood/*metabolism ; Male ; Mice/*embryology ; Pregnancy ; Progesterone/blood ; *Sex Differentiation ; Sex Ratio ; Sexual Behavior, Animal/*physiology ; Testosterone/*blood
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  • 148
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    Evidence for homologous actions of pro-opiocortin products (1980)
    American Association for the Advancement of Science (AAAS)
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    Publication Date: 1980-12-12
    Description: alpha-Melanocyte-stimulating hormone (alpha-MSH), a modified fragment of adrenocorticotropic hormone, derives from the same biosynthetic route as beta-endorphin and is stored by the same arcuate neurons. Microinjection of alpha-melanocyte-stimulating hormone and several related peptides into the periaqueductal gray matter significantly reduced responsiveness to pain and had a behavioral profile similar to that produced by beta-endorphin.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Walker, J M -- Akil, H -- Watson, S J -- 1F32DAO5183/DA/NIDA NIH HHS/ -- New York, N.Y. -- Science. 1980 Dec 12;210(4475):1247-9.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/6254152" target="_blank"〉PubMed〈/a〉
    Keywords: Adrenocorticotropic Hormone/*pharmacology ; Analgesia ; Animals ; Brain/*drug effects ; Cerebral Aqueduct ; Endorphins/*pharmacology ; Male ; Melanocyte-Stimulating Hormones/*pharmacology ; Pain/*physiopathology ; Pituitary Hormones, Anterior/*metabolism ; Pro-Opiomelanocortin ; Protein Precursors/*pharmacology ; Rats
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  • 149
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    Maternal stress alters plasma testosterone in fetal males (1980)
    American Association for the Advancement of Science (AAAS)
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    Publication Date: 1980-01-18
    Description: Titers of testosterone in plasma were determined by radioimmunoassay in male rat fetuses of stressed and control mothers on days 17, 18, 19, 21, and 23 (the day of birth) after conception. In fetuses of stressed mothers, testosterone concentrations were highest on day 17, declined on days 18 and 19, and then remained unchanged. In the control fetuses, testosterone increased from relatively low concentrations on day 17 to the highest amounts on days 18 and 19, and then declined. Thus, the persistence of feminine and impaired masculine sexual behavior in male offspring of stressed mothers could be due to the absence of a surge of circulating testosterone during days 18 and 19 after conception, a period postulated to be critical in the development of the central nervous system in the rat.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Ward, I L -- Weisz, J -- New York, N.Y. -- Science. 1980 Jan 18;207(4428):328-9.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/7188648" target="_blank"〉PubMed〈/a〉
    Keywords: Animals ; Disorders of Sex Development/embryology ; Female ; Fetal Blood/*analysis ; Gestational Age ; Humans ; Male ; Pregnancy ; Rats ; *Sex Differentiation ; Stress, Psychological/blood/*physiopathology ; Testosterone/*blood
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  • 150
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    Behavioral responses to artificial food colors (1980)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1980-03-28
    Description: Twenty-two young children, maintained on a diet that excluded certain foods, were challenged intermittently with a blend of seven artificial colors in a double-blind trial. Parents' observations provided the criteria of response. One child that responded mildly to the challenge and one that responded dramatically were detected. The latter, a 34-month-old female, showed a significant increase in aversive behaviors. These results further confirm previous controlled studies.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Weiss, B -- Williams, J H -- Margen, S -- Abrams, B -- Caan, B -- Citron, L J -- Cox, C -- McKibben, J -- Ogar, D -- Schultz, S -- New York, N.Y. -- Science. 1980 Mar 28;207(4438):1487-9.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/7361103" target="_blank"〉PubMed〈/a〉
    Keywords: Behavior/*drug effects ; Child ; Child, Preschool ; Double-Blind Method ; Female ; Food Coloring Agents/adverse effects/*pharmacology ; Humans ; Hyperkinesis/etiology ; Male
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  • 151
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    Glucose suppresses basal firing and haloperidol-induced increases in the firing rate of central dopaminergic neurons (1980)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1980-12-12
    Description: In the rat, doses of glucose sufficient to raise glucose concentrations in the blood to levels equivalent to those produced by a meal or stress suppress the firing of dopamine-containing neurons located within the substantia nigra. Glucose also prevents or reverses the increase in discharge rates of dopaminergic cells normally elicited by the antipsychotic agent haloperidol.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Saller, C F -- Chiodo, L A -- 5T 32-MH14634/MH/NIMH NIH HHS/ -- MH 16581/MH/NIMH NIH HHS/ -- New York, N.Y. -- Science. 1980 Dec 12;210(4475):1269-71.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/6254155" target="_blank"〉PubMed〈/a〉
    Keywords: Action Potentials/drug effects ; Animals ; Dopamine/*physiology ; Fructose/pharmacology ; Glucose/*pharmacology ; Haloperidol/*antagonists & inhibitors ; Male ; Rats ; Substantia Nigra/*drug effects/physiology ; Synaptic Transmission/*drug effects
    Print ISSN: 0036-8075
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  • 152
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    Asymmetry in facial expression (1980)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1980-08-15
    Description: 〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Sackeim, H A -- Gur, R C -- New York, N.Y. -- Science. 1980 Aug 15;209(4458):834-6.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/7403854" target="_blank"〉PubMed〈/a〉
    Keywords: Emotions ; *Facial Expression ; Female ; *Functional Laterality ; Humans ; Male ; Photography
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  • 153
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    Access of urinary nonvolatiles to the mammalian vomeronasal organ (1980)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1980-02-15
    Description: Guinea pigs were allowed to investigate urine that contained rhodamine, a nonvolatile fluorescent dye. Guinea pigs given free access to dyed urine exhibited fluorescence in their vomeronasal and septal organs but not on their olfactory epithelium. Fluorescence was not seen when unadulterated urine was presented. Thus compounds of low volatility, which do not reach the olfactory epithelium, may stimulate the vomeronasal system and provide information that is normally not provided by gustation or olfaction.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Wysocki, C J -- Wellington, J L -- Beauchamp, G K -- New York, N.Y. -- Science. 1980 Feb 15;207(4432):781-3.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/7352288" target="_blank"〉PubMed〈/a〉
    Keywords: Animals ; Female ; Fluorescent Dyes ; Functional Laterality ; Male ; Nasal Septum/physiology ; *Pheromones ; Sexual Behavior, Animal/physiology ; Smell/*physiology ; Urine/*physiology
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  • 154
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    Auditory brainstem anomalies in human albinos (1980)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1980-09-12
    Description: Brainstem auditory evoked potentials recorded from human albinos indicate significant hemispheric asymmetry. The asymmetry is symptomatic of differences between decussated and nondecussated auditory pathways in albino and pigmented humans at approximately the level of the superior olivary nuclei. Abnormal decussation of auditory pathways in albinos probably coincides with known visual system anomalies.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Creel, D -- Garber, S R -- King, R A -- Witkop, C J Jr -- New York, N.Y. -- Science. 1980 Sep 12;209(4462):1253-5.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/7403883" target="_blank"〉PubMed〈/a〉
    Keywords: Adult ; Albinism/*physiopathology ; Auditory Pathways/*physiopathology ; Brain Stem/*physiopathology ; Evoked Potentials ; Female ; Functional Laterality ; Humans ; Male ; Olivary Nucleus/physiopathology
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  • 155
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    Of human bonding: newborns prefer their mothers' voices (1980)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1980-06-06
    Description: By sucking on a nonnutritive nipple in different ways, a newborn human could produce either its mother's voice or the voice of another female. Infants learned how to produce the mother's voice and produced it more often than the other voice. The neonate's preference for the maternal voice suggests that the period shortly after birth may be important for initiating infant bonding to the mother.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉DeCasper, A J -- Fifer, W P -- New York, N.Y. -- Science. 1980 Jun 6;208(4448):1174-6.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/7375928" target="_blank"〉PubMed〈/a〉
    Keywords: Auditory Perception/*physiology ; Discrimination (Psychology)/physiology ; Female ; Humans ; *Infant, Newborn ; Male ; *Mother-Child Relations ; Sucking Behavior/*physiology
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  • 156
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    Environmental influences on serotonin and cyclic nucleotides in rat cerebral cortex (1980)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1980-11-07
    Description: The response to different environmental conditions and negative air ions was investigated on cerebral cortical serotonin and cyclic nucleotides. The results indicated that negative air ions alter the weight of the cerebral cortex and that concentrations of serotonin and cyclic nucleotides can be altered both by different environments and by negative air ions. The data stress the importance of the role of the environment when studying the structure and chemistry of the cerebral cortex.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Diamond, M C -- Connor, J R Jr -- Orenberg, E K -- Bissell, M -- Yost, M -- Krueger, A -- New York, N.Y. -- Science. 1980 Nov 7;210(4470):652-4.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/6254145" target="_blank"〉PubMed〈/a〉
    Keywords: Animals ; Anions ; Atmosphere ; Brain/growth & development ; Cerebral Cortex/*metabolism ; Crowding ; Cyclic AMP/metabolism ; Cyclic GMP/metabolism ; *Environment ; Male ; Nucleotides, Cyclic/*metabolism ; Rats ; Serotonin/*metabolism
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  • 157
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    Cerebral regional oxygen consumption and supply in anesthetized cat (1980)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1980-07-25
    Description: The study involved quantitative measurement of arterial and venous oxygen saturation, oxygen extraction, blood flow, and oxygen consumption in specific areas of the brain. No regional differences in oxygen consumption were found in anesthetized cat brain, and the amount of oxygen available to all regions studied was more than 2.5 times the consumption throughout the brain.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Buckweitz, E -- Sinha, A K -- Weiss, H R -- New York, N.Y. -- Science. 1980 Jul 25;209(4455):499-501.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/7394515" target="_blank"〉PubMed〈/a〉
    Keywords: Anesthesia, General ; Animals ; Brain/blood supply/drug effects/*metabolism ; Cats ; Chloralose/*pharmacology ; Female ; Male ; Oxygen/*blood ; Oxygen Consumption/*drug effects ; Regional Blood Flow ; Tissue Distribution
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  • 158
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    Acquisition of a memory skill (1980)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1980-06-06
    Description: After more than 230 hours of practice in the laboratory, a subject was able to increase his memory span from 7 to 79 digits. His performance on other memory tests with digits equaled that of memory experts with lifelong training. With an appropriate mnemonic system, there is seemingly no limit to memory performance with practice.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Ericcson, K A -- Chase, W G -- Faloon, S -- New York, N.Y. -- Science. 1980 Jun 6;208(4448):1181-2.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/7375930" target="_blank"〉PubMed〈/a〉
    Keywords: Adult ; Association Learning/physiology ; Humans ; Male ; Memory/*physiology ; Memory, Short-Term/physiology ; Time Factors
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  • 159
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    Relation of mammalian sperm chromatin heterogeneity to fertility (1980)
    American Association for the Advancement of Science (AAAS)
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    Publication Date: 1980-12-05
    Description: Flow cytometry of heated sperm nuclei revealed a significant decrease in resistance to in situ denaturation of spermatozoal DNA in samples from bulls, mice, and humans of low or questionable fertility when compared with others of high fertility. Since thermal denaturation of DNA in situ depends on chromatin structure, it is assumed that changes in sperm chromatin conformation may be related to the diminished fertility. Flow cytometry of heated sperm nuclei may provide a new and independent determinant of male fertility.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Evenson, D P -- Darzynkiewicz, Z -- Melamed, M R -- New York, N.Y. -- Science. 1980 Dec 5;210(4474):1131-3.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/7444440" target="_blank"〉PubMed〈/a〉
    Keywords: Acridine Orange ; Animals ; Cattle ; Cell Nucleus/ultrastructure ; Chromatin/*ultrastructure ; *Fertility ; Hot Temperature ; Humans ; Infertility, Male/*pathology ; Male ; Mice ; Nucleic Acid Denaturation ; Sperm Head/*ultrastructure ; Spermatozoa/*physiology/*ultrastructure ; Zinc/deficiency
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  • 160
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    Long-lasting depletion of striatal dopamine by a single injection of amphetamine in iprindole-treated rats (1980)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1980-07-11
    Description: A single injection of amphetamine given to rats treated concurrently with iprindole so that they could not metabolize the amphetamine by para-hydroxylation resulted in a decrease in the concentration of striatal dopamine 1 week later. The decrease was antagonized by amfonelic acid, an inhibitor of uptake into dopamine neurons. The long-lasting depletion of cerebral dopamine by amphetamine may be analogous to the depletion of cerebral serotonin by halogenated derivatives of amphetamine.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Fuller, R W -- Hemrick-Luecke, S -- New York, N.Y. -- Science. 1980 Jul 11;209(4453):305-7.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/7384808" target="_blank"〉PubMed〈/a〉
    Keywords: Amphetamine/*pharmacology ; Animals ; Brain/drug effects/metabolism ; Corpus Striatum/drug effects/*metabolism ; Dopamine/*metabolism ; Epinephrine/metabolism ; Indoles/*pharmacology ; Iprindole/*pharmacology ; Male ; Naphthyridines/pharmacology ; Norepinephrine/metabolism ; Organ Specificity ; Rats ; p-Chloroamphetamine/pharmacology
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  • 161
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    Ultrastructural demonstration of trypsin-like protease in acrosomes of sea urchin sperm (1980)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1980-07-18
    Description: Two independent cytochemical techniques were used to demonstrate that a trypsin-like protease is bound to the acrosomal tubule of the sea urchin sperm. The enzyme is associated with binding on the reacted acrosome and presumably functions in the early phases of fertilization.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Green, J D -- Summers, R G -- New York, N.Y. -- Science. 1980 Jul 18;209(4454):398-400.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/6992277" target="_blank"〉PubMed〈/a〉
    Keywords: Acrosome/*enzymology/ultrastructure ; Animals ; Histocytochemistry ; Male ; Microscopy, Electron ; Peptide Hydrolases/*analysis ; Sea Urchins ; Spermatozoa/*enzymology ; Trypsin/*analysis
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  • 162
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    Factors influencing the inhibitory effect of selenium on mice inoculated with Ehrlich ascites tumor cells (1980)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1980-08-15
    Description: Selenium, administered to mice with Ehrlich ascites tumors, effectively limited tumor growth. The response was dependent on the chemical form and dose of selenium administered. At the doses administered, there were no detectable adverse effects to the host.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Greeder, G A -- Milner, J A -- New York, N.Y. -- Science. 1980 Aug 15;209(4458):825-7.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/7406957" target="_blank"〉PubMed〈/a〉
    Keywords: Animals ; Carcinoma, Ehrlich Tumor/*drug therapy/pathology ; Cell Line ; Cell Membrane Permeability ; Cystine/analogs & derivatives ; Dose-Response Relationship, Drug ; Male ; Mice ; Neoplasm Transplantation ; Selenium/*administration & dosage/metabolism/therapeutic use ; Selenomethionine/administration & dosage
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  • 163
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    Alterations in brain norepinephrine metabolism induced by environmental stimuli previously paired with inescapable shock (1980)
    American Association for the Advancement of Science (AAAS)
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    Publication Date: 1980-09-05
    Description: Footshock stress produced an immediate increase in brain concentrations of 3-methoxy-4-hydroxyphenylglycol sulfate (MHPG-SO4), a major metabolite of the neurotransmitter norepinephrine, in the rat brain. Twenty-four hours after footshock stress, when concentrations had returned to baseline, increases in MHPG-SO4 and emotional behavior could be elicited by previously neutral environmental stimuli that had been paired with the stress.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Cassens, G -- Roffman, M -- Kuruc, A -- Orsulak, P J -- Schildkraut, J J -- New York, N.Y. -- Science. 1980 Sep 5;209(4461):1138-40.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/7403874" target="_blank"〉PubMed〈/a〉
    Keywords: Animals ; Behavior, Animal/physiology ; Brain/*metabolism ; *Conditioning (Psychology) ; Electroshock ; Environment ; Male ; Methoxyhydroxyphenylglycol/metabolism ; Norepinephrine/*metabolism ; Posture ; Rats ; Stress, Physiological/*metabolism ; Sulfates
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  • 164
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    Successful culture of rat embryos on human serum: use in the detection of teratogens (1980)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1980-03-28
    Description: Growth of head-fold-stage rat embryos cultured with human serum for 48 hours was enhanced by supplementation with glucose. Embryo growth (protein and DNA contents) varied with the source of the serum. Serum from 16 of 19 untreated subjects produced normal embryos. Serum from five subjects undergoing cancer chemotherapy and six subjects receiving anticonvulsants was either lethal or teratogenic.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Chatot, C L -- Klein, N W -- Piatek, J -- Pierro, L J -- New York, N.Y. -- Science. 1980 Mar 28;207(4438):1471-3.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/7361097" target="_blank"〉PubMed〈/a〉
    Keywords: Adult ; Animals ; Anticonvulsants/pharmacology ; Antineoplastic Agents/pharmacology ; Blood ; Culture Media ; *Culture Techniques ; Drug Evaluation, Preclinical/*methods ; *Embryo, Mammalian/drug effects ; Female ; Glucose ; Humans ; Male ; Rats ; *Teratogens
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  • 165
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    Sodium-induced elevation of blood pressure in the anephric state (1980)
    American Association for the Advancement of Science (AAAS)
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    Publication Date: 1980-08-22
    Description: Normotensive anephric rats infused with 2 milliliters of a hyperosmolar solution of either sodium chloride or mannitol showed an increase in arterial pressure that was very pronounced with the sodium chloride and that could be partly abolished by administration of an antagonist to the vasopressor action of antidiuretic hormone (ADH). Rats with congenital ADH deficiency subjected to the same treatment showed smaller increments in arterial pressure that remained unchanged after administration of the ADH antagonist. Expansion of intravascular fluid volume was similar in all four groups and bore no correlation to the change in arterial pressure. It is concluded that about half of the increase in blood pressure induced by saline was attributable to the vasopressor effect of stimulated ADH and the remainder to an additional sodium-related factor, since it was more pronounced in the saline-infused than in the mannitol-infused groups. Expansion of the intravascular volume per se could only account for a minimal part of the increment in pressure.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Hatzinikolaou, P -- Gavras, H -- Brunner, H R -- Gavras, I -- New York, N.Y. -- Science. 1980 Aug 22;209(4459):935-6.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/7403861" target="_blank"〉PubMed〈/a〉
    Keywords: Animals ; Blood Pressure ; *Blood Volume ; Disease Models, Animal ; Hypertension/*etiology/physiopathology ; Male ; *Nephrectomy ; Rats ; Sodium/*blood ; Vasoconstriction ; Vasopressins/antagonists & inhibitors/deficiency/physiology
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  • 166
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    Male contraception; synergism of gonadotropin-releasing hormone analog and testosterone in suppressing gonadotropin (1980)
    American Association for the Advancement of Science (AAAS)
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    Publication Date: 1980-08-22
    Description: Long-term administration of either superactive analog's of gonadotropin-releasing hormone or of testosterone suppresses gonadotropin secretion in male animals and humans. Testosterone administered in combination with gonadotropin-releasing hormone analog further suppresses serum gonadotropin levels in male rats. This observation indicates synergistic activity and suggests that the gonadotropin-releasing hormone analog and testosterone act at independent sites within the hypothalamic-pituitary axis. The primary actions of superactive analog are probably mediated by changes at a postreceptor site in the pituitary gonadotropin-secreting cells.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Heber, D -- Swerdloff, R S -- New York, N.Y. -- Science. 1980 Aug 22;209(4459):936-8.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/6773142" target="_blank"〉PubMed〈/a〉
    Keywords: Animals ; *Contraceptive Agents, Male/pharmacology ; Dose-Response Relationship, Drug ; Drug Synergism ; Follicle Stimulating Hormone/*secretion ; Gonadotropin-Releasing Hormone/*analogs & derivatives/pharmacology ; Luteinizing Hormone/*secretion ; Male ; Rats ; Spermatogenesis/*drug effects ; Testosterone/*pharmacology
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  • 167
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    Differences in the distribution of gray and white matter in human cerebral hemispheres (1980)
    American Association for the Advancement of Science (AAAS)
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    Publication Date: 1980-03-14
    Description: The distribution of gray matter in the two cerebral hemispheres was determined by the xenon-133 inhalation method. There was more gray matter relative to white matter in the left hemisphere than in the right, particularly in the frontal and precentral regions. This finding suggests that the organization of the left hemisphere, relative to that of the right, emphasizes processing or transfer within regions, or both, rather than transfer across regions.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Gur, R C -- Packer, I K -- Hungerbuhler, J P -- Reivich, M -- Obrist, W D -- Amarnek, W S -- Sackeim, H A -- New York, N.Y. -- Science. 1980 Mar 14;207(4436):1226-8.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/7355287" target="_blank"〉PubMed〈/a〉
    Keywords: Brain/*anatomy & histology ; Cerebrovascular Circulation ; Functional Laterality ; Humans ; Male ; Xenon Radioisotopes
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  • 168
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    Increased dopamine receptor sensitivity after estrogen treatment using the rat rotation model (1980)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1980-06-27
    Description: Estrogen was administered to male rats that had received unilateral injections of 6-hydroxydopamine into the striatum. Following this treatment, their duration of rotation increased in response to amphetamine. Estrogen treatment resulted in a corresponding increase in the number of striatal dopamine receptors. Therefore, both behavioral and biochemical evidence suggests that striatal dopamine function is influenced by peripherally administered estrogens. These results are relevant to the clinical cases of chorea associated with elevated concentrations of estrogen, which occur in pregnancy and during oral contraceptive use.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Hruska, R E -- Silbergeld, E K -- New York, N.Y. -- Science. 1980 Jun 27;208(4451):1466-8.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/7189902" target="_blank"〉PubMed〈/a〉
    Keywords: Animals ; Apomorphine/pharmacology ; Corpus Striatum/drug effects/*metabolism ; Dextroamphetamine/pharmacology ; Estradiol/*pharmacology ; Humans ; Hydroxydopamines/*pharmacology ; Male ; Rats ; Receptors, Dopamine/drug effects/*metabolism ; Rotation ; Spiperone/metabolism ; Stereotyped Behavior
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  • 169
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    Dexamethasone fails to suppress beta-endorphin plasma concentrations in humans and rhesus monkeys (1980)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1980-08-15
    Description: In humans and rhesus monkeys, dexamethasone decreased concentrations of plasma cortisol but did not alter circulating beta-endorphin immunoreactivity. Contrary to current theory suggesting that pituitary beta-endorphin and adrenocorticotropic hormone are controlled by identical regulatory mechanisms for synthesis and release, our evidence suggests that in higher primates the established glucocorticoid feedback mechanism for the adrenocorticotropic hormone-cortisol system does not regulate beta-endorphin secretion in the same way.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Kalin, N H -- Risch, S C -- Cohen, R M -- Insel, T -- Murphy, D L -- New York, N.Y. -- Science. 1980 Aug 15;209(4458):827-8.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/6250217" target="_blank"〉PubMed〈/a〉
    Keywords: Adrenocorticotropic Hormone/secretion ; Adult ; Animals ; Dexamethasone/*pharmacology ; Endorphins/*blood/secretion ; Feedback ; Female ; Haplorhini ; Humans ; Hydrocortisone/blood ; Macaca mulatta ; Male ; Pituitary Gland, Anterior/secretion ; Protein Precursors/metabolism ; Species Specificity ; Stress, Physiological/blood
    Print ISSN: 0036-8075
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  • 170
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    Auditory and vocal nuclei in the frog brain concentrate sex hormones (1980)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1980-02-01
    Description: Mate calling by South African clawed frogs, Xenopus laevis, is under the control of androgens. Autoradiographic studies demonstrate androgen-concentrating neurons in a motor nucleus that controls mate calling and a midbrain nucleus that is stimulated by sound. Hormone concentration by laryngeal motor neurons suggests that steroids regulate the final common path for vocal behavior. Modulation of auditory sensitivity by hormones could explain seasonal variations in behavioral responsiveness to conspecific vocalizations.〈br /〉〈br /〉〈a href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3493211/" target="_blank"〉〈img src="https://static.pubmed.gov/portal/portal3rc.fcgi/4089621/img/3977009" border="0"〉〈/a〉   〈a href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3493211/" target="_blank"〉This paper as free author manuscript - peer-reviewed and accepted for publication〈/a〉〈br /〉〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Kelley, D B -- R01 NS023684/NS/NINDS NIH HHS/ -- New York, N.Y. -- Science. 1980 Feb 1;207(4430):553-5.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/7352269" target="_blank"〉PubMed〈/a〉
    Keywords: Animals ; Auditory Pathways/*metabolism ; Auditory Perception/physiology ; Autoradiography ; Brain/*metabolism ; Brain Mapping ; Dihydrotestosterone/*metabolism ; Male ; Mesencephalon/metabolism ; Vocalization, Animal/*physiology ; Xenopus/*physiology
    Print ISSN: 0036-8075
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  • 171
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    Math and sex: are girls born with less ability? (1980)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1980-12-12
    Description: 〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Kolata, G B -- New York, N.Y. -- Science. 1980 Dec 12;210(4475):1234-5.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/7434024" target="_blank"〉PubMed〈/a〉
    Keywords: Environment ; Female ; Humans ; Intelligence ; Male ; *Mathematics ; *Sex Factors
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  • 172
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    Erythrosine (Red No. 3) and its nonspecific biochemical actions: what relation to behavioral changes? (1980)
    American Association for the Advancement of Science (AAAS)
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    Publication Date: 1980-02-01
    Description: Biochemical studies have shown that the ability of erythrosine to inhibit dopamine uptake into brain synaptosomal preparations is dependent on the concentration of tissue present in the assay mixture. Thus, the finding that erythrosine inhibits dopamine uptake (which, if true, would provide a plausible explanation of the Feingold hypothesis of childhood hyperactivity) may simply be an artifact that results from nonspecific interactions with brain membranes. In addition, although erythrosine given parenterally (50 milligrams per kilogram) did not alter locomotor activity of control of 6-hydroxydopamine-treated rats, erythrosine (50 to 300 milligrams per kilogram) attenuated the effect of punishment in a "conflict" paradigm.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Mailman, R B -- Ferris, R M -- Tang, F L -- Vogel, R A -- Kilts, C D -- Lipton, M A -- Smith, D A -- Mueller, R A -- Breese, G R -- New York, N.Y. -- Science. 1980 Feb 1;207(4430):535-7.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/7352264" target="_blank"〉PubMed〈/a〉
    Keywords: Animals ; Behavior, Animal/*drug effects ; Biological Transport/drug effects ; Brain/*drug effects/metabolism ; Dopamine/*metabolism ; Food Coloring Agents/*pharmacology ; Hydroxydopamines/pharmacology ; Male ; Motor Activity/drug effects ; Nerve Tissue Proteins/metabolism ; Rats ; Synaptosomes/metabolism
    Print ISSN: 0036-8075
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  • 173
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    Mental symptoms in Huntington's disease and a possible primary aminergic neuron lesion (1980)
    American Association for the Advancement of Science (AAAS)
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    Publication Date: 1980-12-19
    Description: Monoamine oxidase activity was higher in the cerebral cortex and basal ganglia of patients dying from Huntington's disease than in controls. Enzyme kinetics and multiple substrate studies indicated that the increased activity was due to elevated concentrations of monoamine oxidase type B. Concentrations of homovanillic acid were increased in the cerebral cortex but not in the basal ganglia of brains of patients with Huntington's disease. These changes may represent a primary aminergic lesion that could underlie some of the mental symptoms of this disease.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Mann, J J -- Stanley, M -- Gershon, S -- Rossor, M -- New York, N.Y. -- Science. 1980 Dec 19;210(4476):1369-71.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/6449080" target="_blank"〉PubMed〈/a〉
    Keywords: Basal Ganglia/*enzymology ; Cerebral Cortex/*enzymology ; Dopamine/physiology ; Female ; Homovanillic Acid/*metabolism ; Humans ; Huntington Disease/complications/*physiopathology ; Male ; Monoamine Oxidase/*metabolism ; Phenylacetates/*metabolism ; Psychotic Disorders/etiology/physiopathology ; Substrate Specificity
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  • 174
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    AMIS negative on aspirin and heart attacks (1980)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1980-02-22
    Description: 〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Marx, J L -- New York, N.Y. -- Science. 1980 Feb 22;207(4433):859-60.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/6986648" target="_blank"〉PubMed〈/a〉
    Keywords: Aspirin/*therapeutic use ; Blood Coagulation/drug effects ; Clinical Trials as Topic ; Female ; Humans ; Ischemic Attack, Transient/prevention & control ; Male ; Myocardial Infarction/*prevention & control ; Time Factors
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  • 175
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    Monkey responses to three different alarm calls: evidence of predator classification and semantic communication (1980)
    American Association for the Advancement of Science (AAAS)
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    Publication Date: 1980-11-14
    Description: Vervet monkeys give different alarm calls to different predators. Recordings of the alarms played back when predators were absent caused the monkeys to run into trees for leopard alarms, look up for eagle alarms, and look down for snake alarms. Adults call primarily to leopards, martial eagles, and pythons, but infants give leopard alarms to various mammals, eagle alarms to many birds, and snake alarms to various snakelike objects. Predator classification improves with age and experience.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Seyfarth, R M -- Cheney, D L -- Marler, P -- MH07446/MH/NIMH NIH HHS/ -- New York, N.Y. -- Science. 1980 Nov 14;210(4471):801-3.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/7433999" target="_blank"〉PubMed〈/a〉
    Keywords: *Animal Communication ; Animals ; Behavior, Animal/*physiology ; Cercopithecidae/*physiology ; *Fear ; Female ; Male ; Predatory Behavior ; Vocalization, Animal
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  • 176
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    The testicular feminized rat: a naturally occurring model of androgen independent brain masculinization (1980)
    American Association for the Advancement of Science (AAAS)
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    Publication Date: 1980-07-18
    Description: Although genotypically male (XY), the testicular feminized rat develops as an anatomic female because of an inherited deficiency in intracellular androgen receptors that prevents androgen imprinting of sexual primordia. However, the ability of testicular feminized rats to exhibit male-like sexual behavior and little feminine sexual behavior suggests that the brain can be masculinized without androgens.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Shapiro, B H -- Levine, D C -- Adler, N T -- New York, N.Y. -- Science. 1980 Jul 18;209(4454):418-20.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/7384816" target="_blank"〉PubMed〈/a〉
    Keywords: Androgen-Insensitivity Syndrome/*physiopathology ; Animals ; Brain/*physiopathology ; Castration ; Estradiol/pharmacology ; Female ; Male ; Posture ; Rats ; Sex Factors ; *Sexual Behavior, Animal/drug effects ; Testosterone/pharmacology
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  • 177
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    Synthesis of human plasminogen by the liver (1980)
    American Association for the Advancement of Science (AAAS)
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    Publication Date: 1980-05-30
    Description: Genetic types of plasminogen were determined from a donor and a recipient before and after hepatic homotransplantation. Examination of the plasminogen types demonstrated that the liver is the principal site of synthesis of human plasminogen.〈br /〉〈br /〉〈a href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2981173/" target="_blank"〉〈img src="https://static.pubmed.gov/portal/portal3rc.fcgi/4089621/img/3977009" border="0"〉〈/a〉   〈a href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2981173/" target="_blank"〉This paper as free author manuscript - peer-reviewed and accepted for publication〈/a〉〈br /〉〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Raum, D -- Marcus, D -- Alper, C A -- Levey, R -- Taylor, P D -- Starzl, T E -- R01 AM007772/AM/NIADDK NIH HHS/ -- New York, N.Y. -- Science. 1980 May 30;208(4447):1036-7.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/6990488" target="_blank"〉PubMed〈/a〉
    Keywords: Female ; Humans ; Liver/*metabolism ; Liver Transplantation ; Male ; Plasminogen/*biosynthesis/genetics ; Polymorphism, Genetic ; Transplantation, Homologous
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  • 178
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    Esterase 6 and reproduction in Drosophila melanogaster (1980)
    American Association for the Advancement of Science (AAAS)
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    Publication Date: 1980-03-28
    Description: A nonspecific carboxylesterase (esterase 6) of Drosophila melanogaster shows greater activity in adult males than in females and is highly concentrated in the anterior ejaculatory duct of the reproductive tract of the male. Esterase 6 is depleted in males by copulation and is transferred to females early during copulation as a component of the seminal fluid. That esterase 6 may be involved in a system controlling the timing of remating is suggested by differences in the activity of this enzyme in a strain of Drosophila selected for a decrease in time to remating and by differences in the timing of remating in females initially inseminated by males lacking or having active esterase 6.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Richmond, R C -- Gilbert, D G -- Sheehan, K B -- Gromko, M H -- Butterworth, F M -- New York, N.Y. -- Science. 1980 Mar 28;207(4438):1483-5.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/6767273" target="_blank"〉PubMed〈/a〉
    Keywords: Animals ; Carboxylic Ester Hydrolases/genetics/*metabolism ; Drosophila melanogaster/*enzymology/physiology ; Female ; Genitalia, Female/enzymology ; Male ; Polymorphism, Genetic ; Reproduction ; Semen/enzymology ; Sexual Behavior, Animal
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  • 179
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    Gastrin injected into the lateral hypothalamus stimulates secretion of gastric acid in rats (1980)
    American Association for the Advancement of Science (AAAS)
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    Publication Date: 1980-09-05
    Description: Intrahypothalamic injections of 100 picomoles of pentagastrin or natural gastrin promptly increased secretion of gastric acid in conscious rats. The response was blocked by atropine and by vagotomy. The same doses, injected intravenously or into other forebrain sites, did not increase secretion, nor did intrahypothalamic injections of other peptides common to the gut and brain.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Tepperman, B L -- Evered, M D -- New York, N.Y. -- Science. 1980 Sep 5;209(4461):1142-3.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/7403876" target="_blank"〉PubMed〈/a〉
    Keywords: Animals ; Gastric Juice/*secretion ; Gastrins/*pharmacology ; Hypothalamus/*drug effects/*physiology ; Male ; Pentagastrin/blood/pharmacology ; Rats ; Stimulation, Chemical
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  • 180
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    Gonadal steroids: effects on excitability of hippocampal pyramidal cells (1980)
    American Association for the Advancement of Science (AAAS)
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    Publication Date: 1980-08-29
    Description: Electrophysiological field potentials from hippocampal slices of rat brain show sex-linked differences in response to 1 X 10(-10)M concentrations of estradiol and testosterone added to the incubation medium. Slices from male rats show increased excitability to estradiol and not to testosterone. Slices from female rats are not affected by estradiol, but slices from female rats in diestrus show increased excitability in response to testosterone whereas slices from females in proestrus show decreased excitability.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Teyler, T J -- Vardaris, R M -- Lewis, D -- Rawitch, A B -- New York, N.Y. -- Science. 1980 Aug 29;209(4460):1017-8.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/7190730" target="_blank"〉PubMed〈/a〉
    Keywords: Action Potentials/drug effects ; Animals ; Biotransformation ; Diestrus ; Estradiol/metabolism/*pharmacology ; *Estrus ; Female ; Hippocampus/*drug effects ; Male ; Membrane Potentials/drug effects ; Pregnancy ; Proestrus ; Pyramidal Tracts/*drug effects ; Rats ; Sex Differentiation ; Testosterone/*pharmacology
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  • 181
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    Neuronal loss in hippocampus induced by prolonged ethanol consumption in rats (1980)
    American Association for the Advancement of Science (AAAS)
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    Publication Date: 1980-08-08
    Description: Quantitative neurohistological techniques were used to examine the hippocampal complex of laboratory rats maintained on ethanol-containing or control diets for 5 months followed by a 2-month alcohol-free period. Chronic ethanol consumption resulted in a significant loss of hippocampal pyramidal and dentate gyrus granule cells. This study provides direct evidence that long-term ethanol consumption, in the absence of malnutrition, produces neuronal loss in the central nervous system.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Walker, D W -- Barnes, D E -- Zornetzer, S F -- Hunter, B E -- Kubanis, P -- New York, N.Y. -- Science. 1980 Aug 8;209(4457):711-3.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/7394532" target="_blank"〉PubMed〈/a〉
    Keywords: Animals ; Ethanol/*pharmacology ; Hippocampus/drug effects/*physiology ; Male ; Neurons/drug effects/*physiology ; Pyramidal Tracts/drug effects/physiology ; Rats ; Time Factors
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  • 182
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    Cholecystokinin receptors in the brain: characterization and distribution (1980)
    American Association for the Advancement of Science (AAAS)
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    Publication Date: 1980-06-06
    Description: Specific cholecystokinin binding sites in particulate fractions of rat brain were measured with iodine 125-labeled Bolton-Hunter cholecystokinin, a cholecystokinin analog that has full biological activity. Binding was detected in brain regions known to contain immunoreactive cholecystokinin. Binding was saturable, reversible, of high affinity (dissociation constant, 1.7 x 10(-9) M), and was inhibited by cholecystokinin analogs but not by unrelated hormones.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Saito, A -- Sankaran, H -- Goldfine, I D -- Williams, J A -- New York, N.Y. -- Science. 1980 Jun 6;208(4448):1155-6.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/6246582" target="_blank"〉PubMed〈/a〉
    Keywords: Animals ; Binding, Competitive ; Brain/*metabolism ; Brain Mapping ; Cerebral Cortex/metabolism ; Cholecystokinin/*metabolism ; Gastrins/metabolism ; Kinetics ; Male ; Olfactory Bulb/metabolism ; Pancreas/metabolism ; Rats ; Receptors, Cell Surface/*metabolism
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  • 183
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    Inhibition of biological activity of mouse beta-nerve growth factor by monoclonal antibody (1980)
    American Association for the Advancement of Science (AAAS)
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    Publication Date: 1980-11-21
    Description: A continuous hybrid cell line was derived that secretes monoclonal antibody capable of inhibiting the biological activity of mouse beta-nerve growth factor (beta-NGF). Results obtained with monovalent fragments indicate that the monoclonal antibody inhibits activity by interfering with the direct interaction between beta-NGF and the cell membrane receptor rather than by precipitating the dimeric form of beta-NGF. This monoclonal antibody binds to an antigenic determinant common to mouse beta-NGF, snake venom (Naja naja) beta-NGF, and human beta-NGF. These antibodies should provide specific molecular probes for a variety of studies of nerve growth factor including its tissue distribution and mechanism of action.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Warren, S L -- Fanger, M -- Neet, K E -- A110148/PHS HHS/ -- CA27915/CA/NCI NIH HHS/ -- New York, N.Y. -- Science. 1980 Nov 21;210(4472):910-2.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/6159686" target="_blank"〉PubMed〈/a〉
    Keywords: Animals ; Antigen-Antibody Reactions ; Clone Cells/immunology ; Epitopes ; Hybrid Cells ; Immunoglobulin Fab Fragments ; Male ; Mice ; Nerve Growth Factors/*antagonists & inhibitors/immunology ; Receptors, Cell Surface/immunology
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  • 184
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    Primate memory: retention of serial list items by a rhesus monkey (1980)
    American Association for the Advancement of Science (AAAS)
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    Publication Date: 1980-08-22
    Description: A rhesus monkey correctly recognized 86 and 81 percent of 10- and 20-item lists, respectively. It serial position curve was similar in form to a human's curve, revealing prominent primacy and recency effects. The key to these findings was in minimizing proactive interference through the use of a large pool of 211 color photographs.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Sands, S F -- Wright, A A -- New York, N.Y. -- Science. 1980 Aug 22;209(4459):938-40.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/6773143" target="_blank"〉PubMed〈/a〉
    Keywords: Adult ; Animals ; Female ; Haplorhini ; Humans ; Macaca/*physiology ; Macaca mulatta/*physiology ; Male ; Memory/*physiology ; Memory, Short-Term/physiology ; Methods ; Retention (Psychology)/*physiology
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    Artificial sweetener use and bladder cancer: a case-control study (1980)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1980-03-14
    Description: In a case-control study of 302 male and 65 female bladder cancer patients and an equal number of other patients matched to them in age, sex, hospital, and hospital-room status, no association was found between use of artificial sweeteners or diet beverages and bladder cancer. No dose-response was observed with respect to quantity or duration of use of the two combined. No evidence was found to suggest that artificial sweeteners or diet beverages promote the tumorigenic effect of tobacco smoking. Artificial sweetener and diet beverage use strongly reflected socioeconomic status among controls with various diagnoses.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Wynder, E L -- Stellman, S D -- New York, N.Y. -- Science. 1980 Mar 14;207(4436):1214-6.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/7355283" target="_blank"〉PubMed〈/a〉
    Keywords: Female ; Humans ; Male ; Sex Factors ; Smoking/*complications ; Sweetening Agents/*adverse effects ; Urinary Bladder Neoplasms/chemically induced/*etiology
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
    Published by American Association for the Advancement of Science (AAAS)
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