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  • 1
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    American Association for the Advancement of Science (AAAS)
    Publication Date: 1984-07-20
    Description: 〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Carroll, P T -- New York, N.Y. -- Science. 1984 Jul 20;225(4659):306.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/17749557" target="_blank"〉PubMed〈/a〉
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
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  • 2
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    American Association for the Advancement of Science (AAAS)
    Publication Date: 1995-09-29
    Description: 〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Carroll, P T -- New York, N.Y. -- Science. 1995 Sep 29;269(5232):1891-3.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/17820247" target="_blank"〉PubMed〈/a〉
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
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  • 3
    Publication Date: 1978-11-10
    Description: beta,beta'-Iminodipropionitrile (IDPN) administration prevented normal slow axonal transport of [35S]methionine- or [3H]leucine-labeled proteins in rat sciatic motor axons. Ultrastructural and electrophoretic studies showed that the neurofilament triplet proteins in particular were retained within the initial 5 millimeters of the axons, resulting in neurofilament-filled axonal swellings. Fast anterograde and retrograde axonal transport were not affected. The IDPN thus selectively impaired slow axonal transport. The neurofibrillary pathology in this model is the result of the defective slow transport of neurofilaments.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Griffin, J W -- Hoffman, P N -- Clark, A W -- Carroll, P T -- Price, D L -- New York, N.Y. -- Science. 1978 Nov 10;202(4368):633-5.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/81524" target="_blank"〉PubMed〈/a〉
    Keywords: Axonal Transport/*drug effects ; Kinetics ; Molecular Weight ; Nerve Tissue Proteins/*metabolism ; Neurofibrils/metabolism/ultrastructure ; Nitriles/*pharmacology/toxicity ; Sciatic Nerve/metabolism
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
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  • 4
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    American Association for the Advancement of Science (AAAS)
    Publication Date: 1980-11-07
    Description: Samples of minced mouse forebrain were treated in a way that resulted in a high ratio of false cholinergic transmitter (acetylhomocholine) to true transmitter (acetylcholine) in a synaptic vesicle fraction, and a low ratio of false to true transmitter in the nerve terminal cytoplasm. The spontaneous release of cholinergic transmitters from this minced tissue occurred independently of calcium and had a ratio of false to true transmitter similar to that of the cytoplasm, whereas the evoked transmitter release required calcium and had a ratio of false to true transmitter similar to that of the vesicular fraction.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Carroll, P T -- Aspry, J M -- New York, N.Y. -- Science. 1980 Nov 7;210(4470):641-2.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/7433989" target="_blank"〉PubMed〈/a〉
    Keywords: Acetylcholine/analogs & derivatives/*metabolism ; Animals ; Brain/*metabolism ; Calcium/physiology ; Cytoplasm/metabolism ; Exocytosis/drug effects ; Lithium/pharmacology ; Magnesium/physiology ; Male ; Mice ; Potassium/pharmacology ; Synaptic Vesicles/metabolism
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
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  • 5
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    American Association for the Advancement of Science (AAAS)
    Publication Date: 1980-07-04
    Description: For many years American science in the late 19th century was regarded as an intellectual backwater. This view derived from the assumption that the health of American science at the time was equivalent to the condition of pure science, especially pure physics. However, a closer look reveals that there was considerable vitality in American scientific research, especially in the earth and life sciences. This vitality is explainable in part by the natural scientific resources of the American continent but also in part by the energy given science from religious impulses, social reformism, and practicality. Furthermore, contrary to recent assumptions, the federal government was a significant patron of American science. The portrait of American science circa 1880 advanced in this article suggests that the nation's scientific enterprise was characterized by pluralism of institutional support and motive and that such pluralism has historically been the normal mode.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Kevles, D J -- Sturchio, J L -- Carroll, P T -- New York, N.Y. -- Science. 1980 Jul 4;209(4452):27-32.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/17836559" target="_blank"〉PubMed〈/a〉
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
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  • 6
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    American Association for the Advancement of Science (AAAS)
    Publication Date: 1980-07-04
    Description: For many years American science in the late 19th century was regarded as an intellectual backwater. This view derived from the assumption that the health of American science at the time was equivalent to the condition of pure science, especially pure physics. However, a closer look reveals that there was considerable vitality in American scientific research, especially in the earth and life sciences. This vitality is explainable in part by the natural scientific resources of the American continent but also in part by the energy given science from religious impulses, social reformism, and practicality. Furthermore, contrary to recent assumptions, the federal government was a significant patron of American science. The portrait of American science circa 1880 advanced in this article suggests that the nation's scientific enterprise was characterized by pluralism of institutional support and motive and that such pluralism has historically been the normal mode.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Kevles, D J -- Sturchio, J L -- Carroll, P T -- New York, N.Y. -- Science. 1980 Jul 4;209(4452):26-32.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/7025200" target="_blank"〉PubMed〈/a〉
    Keywords: Government ; History, 19th Century ; Periodicals as Topic/history ; Religion and Science ; Research ; Science/*history ; United States
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
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  • 7
    Publication Date: 2016-10-14
    Description: Bell et al. reported the first detection of the cyanopolyyne HC 11 N towards the cold dark cloud TMC-1; no subsequent detections have been reported towards any source. Additional observations of cyanopolyynes and other carbon-chain molecules towards TMC-1 have shown a log-linear trend between molecule size and column density, and in an effort to further explore the underlying chemical processes driving this trend, we have analysed Green Bank Telescope observations of HC 9 N and HC 11 N towards TMC-1. Although we find an HC 9 N column density consistent with previous values, HC 11 N is not detected and we derive an upper limit column density significantly below that reported in Bell et al. Using a state-of-the-art chemical model, we have investigated possible explanations of non-linearity in the column density trend. Despite updating the chemical model to better account for ion–dipole interactions, we are not able to explain the non-detection of HC 11 N, and we interpret this as evidence of previously unknown carbon-chain chemistry. We propose that cyclization reactions may be responsible for the depleted HC 11 N abundance, and that products of these cyclization reactions should be investigated as candidate interstellar molecules.
    Print ISSN: 0035-8711
    Electronic ISSN: 1365-2966
    Topics: Physics
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