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  • American Association for the Advancement of Science (AAAS)  (2,084)
  • 1980-1984  (2,084)
  • 1950-1954
  • 1984  (2,084)
  • 101
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    EPA review of lead study (1984)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1984-01-13
    Description: 〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉New York, N.Y. -- Science. 1984 Jan 13;223(4632):116-8.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/6691138" target="_blank"〉PubMed〈/a〉
    Keywords: Child ; Environmental Exposure ; Humans ; *Intelligence ; *Lead ; United States ; United States Environmental Protection Agency
    Print ISSN: 0036-8075
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    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
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  • 102
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    Volunteers invited for museum project (1984)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1984-01-13
    Description: 〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉New York, N.Y. -- Science. 1984 Jan 13;223(4632):159.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/17733797" target="_blank"〉PubMed〈/a〉
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    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
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  • 103
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    Indian development trends (1984)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1984-08-03
    Description: 〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Abelson, P H -- New York, N.Y. -- Science. 1984 Aug 3;225(4661):463.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/17750829" target="_blank"〉PubMed〈/a〉
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  • 104
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    Erratum (1984)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1984-01-13
    Description: In the Research News article "New test of variable gravitational constant" (23 Dec., p. 1316), in the third paragraph of column two on page 1317, a minus sign was left out of an exponent. The correct value for the drift of atomic clocks relative to gravitational clocks is (0.1 +/- 0.8) x 10(-11) per year.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉New York, N.Y. -- Science. 1984 Jan 13;223(4632):118.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/17733781" target="_blank"〉PubMed〈/a〉
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    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
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  • 105
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    Hemispheric cooperation in science (1984)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1984-09-14
    Description: 〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Abelson, P H -- New York, N.Y. -- Science. 1984 Sep 14;225(4667):1107.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/17782405" target="_blank"〉PubMed〈/a〉
    Print ISSN: 0036-8075
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    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
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  • 106
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    Materials science and engineering (1984)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1984-11-09
    Description: 〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Abelson, P H -- New York, N.Y. -- Science. 1984 Nov 9;226(4675):613.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/17774923" target="_blank"〉PubMed〈/a〉
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    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
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  • 107
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    Analytical instruments (1984)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1984-10-19
    Description: 〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Abelson, P H -- New York, N.Y. -- Science. 1984 Oct 19;226(4672):249.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/17749869" target="_blank"〉PubMed〈/a〉
    Print ISSN: 0036-8075
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    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
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  • 108
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    Ca2+-dependent protein kinase injection in a photoreceptor mimics biophysical effects of associative learning (1984)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1984-06-15
    Description: Iontophoretic injection of phosphorylase kinase, a Ca2+-calmodulin-dependent protein kinase, increased input resistance, enhanced the long-lasting depolarization component of the light response, and reduced the early transient outward K+ current, IA, and the late K+ currents, IB, in type B photoreceptors of Hermissenda crassicornis in a Ca2+-dependent manner. Since behavioral and biophysical studies have shown that similar membrane changes persist after associative conditioning, these results suggest that Ca2+-dependent protein phosphorylation could mediate the long-term modulation of specific K+ channels as a step in the generation of a coditioned behavioral change.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Acosta-Urquidi, J -- Alkon, D L -- Neary, J T -- New York, N.Y. -- Science. 1984 Jun 15;224(4654):1254-7.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/6328653" target="_blank"〉PubMed〈/a〉
    Keywords: Action Potentials/drug effects ; Animals ; *Association Learning ; Horseshoe Crabs ; Ion Channels/drug effects ; Iontophoresis ; *Learning ; Light ; Mollusca ; Phosphorylase Kinase/*pharmacology ; Photoreceptor Cells/*drug effects ; Potassium/metabolism
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    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
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  • 109
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    Plasticity of substance P in mature and aged sympathetic neurons in culture (1984)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1984-09-28
    Description: The effect of age on the plasticity of the putative peptide neurotransmitter substance P (SP) was examined in the rat superior cervical sympathetic ganglion. Explantation of ganglia from 6-month-old rats to serum-supplemented culture resulted in a tenfold increase in SP concentration, reproducing results previously obtained for ganglia from neonatal rats. Veratridine prevented the increase in SP concentration in adult ganglia, and tetrodotoxin blocked the veratridine effect, suggesting that membrane depolarization and sodium influx prevented the rise in the SP content of adult ganglia as well as of neonatal ganglia. However, the time courses of the increase in the amount of the peptide differed in neonatal and mature ganglia, suggesting that some aspects of regulation may differ in the two. The effects of aging on neural plasticity were further analyzed by explanting ganglia from 2-year-old rats. No significant increase in SP concentration was observed in these ganglia. Remarkable plasticity thus seems to persist in mature neurons but may be deficient in aged sympathetic neurons.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Adler, J E -- Black, I B -- HD 12108/HD/NICHD NIH HHS/ -- NS 10259/NS/NINDS NIH HHS/ -- New York, N.Y. -- Science. 1984 Sep 28;225(4669):1499-500.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/6206570" target="_blank"〉PubMed〈/a〉
    Keywords: Aging ; Animals ; Culture Techniques ; Ganglia, Sympathetic/*analysis/cytology/physiology ; *Neuronal Plasticity ; Neurons/*analysis/physiology ; Rats ; Substance P/*analysis ; Tetrodotoxin/pharmacology ; Veratridine/pharmacology
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  • 110
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    Gas reactors (1984)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1984-06-29
    Description: 〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Agnew, H M -- Johnston, T A -- New York, N.Y. -- Science. 1984 Jun 29;224(4656):1382.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/17793356" target="_blank"〉PubMed〈/a〉
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  • 111
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    Spacelab 1 (1984)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1984-07-13
    Description: 〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Abelson, P H -- New York, N.Y. -- Science. 1984 Jul 13;225(4658):127.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/17837907" target="_blank"〉PubMed〈/a〉
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  • 112
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    Groundwater contamination (1984)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1984-05-18
    Description: 〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Abelson, P H -- New York, N.Y. -- Science. 1984 May 18;224(4650):673.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/17780578" target="_blank"〉PubMed〈/a〉
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  • 113
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    Recombinant DNA committee (1984)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1984-02-03
    Description: 〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Ahmed, A K -- New York, N.Y. -- Science. 1984 Feb 3;223(4635):440.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/6691155" target="_blank"〉PubMed〈/a〉
    Keywords: *Advisory Committees ; *Containment of Biohazards ; *DNA, Recombinant ; *Federal Government ; *Government Regulation ; *National Institutes of Health (U.S.) ; United States
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  • 114
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    Avian pancreatic polypeptide phase shifts hamster circadian rhythms when microinjected into the suprachiasmatic region (1984)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1984-02-24
    Description: The suprachiasmatic nucleus has been identified tentatively as a circadian pacemaker. To examine the functional role of peptides found within suprachiasmatic neurons, avian pancreatic polypeptide and vasopressin were microinjected into the suprachiasmatic region. Avian pancreatic polypeptide, but not vasopressin, shifted the phase of the wheelrunning rhythm as a function of the time of its injection within the circadian cycle. Avian pancreatic polypeptide or a similar peptide may be one component of the neurochemical processes underlying entrainment to the light-dark cycle.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Albers, H E -- Ferris, C F -- Leeman, S E -- Goldman, B D -- GM-31199/GM/NIGMS NIH HHS/ -- HD-18022/HD/NICHD NIH HHS/ -- New York, N.Y. -- Science. 1984 Feb 24;223(4638):833-5.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/6546454" target="_blank"〉PubMed〈/a〉
    Keywords: Animals ; Birds ; Cerebral Ventricles/drug effects ; *Circadian Rhythm ; Cricetinae ; Motor Activity/drug effects ; Nerve Tissue Proteins/pharmacology ; Neuropeptide Y ; Pancreatic Polypeptide/*pharmacology ; Species Specificity ; Suprachiasmatic Nucleus/*drug effects ; Vasopressins/pharmacology
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  • 115
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    Magendie and his milieu: science and medicine in france (1984)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1984-06-15
    Description: 〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Albury, W R -- New York, N.Y. -- Science. 1984 Jun 15;224(4654):1229-30.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/17819489" target="_blank"〉PubMed〈/a〉
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  • 116
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    Physician-investigators (1984)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1984-03-02
    Description: 〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Alderson, L M -- New York, N.Y. -- Science. 1984 Mar 2;223(4639):878.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/17781607" target="_blank"〉PubMed〈/a〉
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  • 117
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    Biotechnology as an intellectual property (1984)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1984-04-27
    Description: Recent advances in biotechnology have created many public policy and legal issues, one of the most significant of which is the treatment of biotechnological industrial products, particularly under the patent system. Patents represent one of several types of intellectual property; their ownership confers the right to exclude others from benefitting from the tangible products of a proprietary subject matter. Intellectual property law and its protections will play a major role in the rate at which biotechnology develops in the United States. In this article biotechnological intellectual property issues are reviewed in the context of their underlying legal requirements. The implications of other factors, such as international competition, research funding, and gene ownership, are also considered.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Adler, R G -- New York, N.Y. -- Science. 1984 Apr 27;224(4647):357-63.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/6584975" target="_blank"〉PubMed〈/a〉
    Keywords: *Biomedical Research ; Cell Line ; Copyright ; DNA, Recombinant ; Economic Competition ; Federal Government ; *Genetic Engineering ; *Genetics, Microbial ; Government Regulation ; Legislation as Topic ; Ownership ; *Patents as Topic ; Research ; *Technology ; United States ; as a question of intellectual property rights. Attention is focused on the major ; role played by the U.S. patent system in establishing such rights, as illustrated ; by the case of products of recombinant DNA research. Trade secret, copyright, and ; trademark protections are also considered, as are policy issues such as ; international competition in the development of biomedical technologies and ; financing arrangements.
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  • 118
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    Progress toward energy security (1984)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1984-01-13
    Description: 〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Abelson, P H -- New York, N.Y. -- Science. 1984 Jan 13;223(4632):121.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/17733784" target="_blank"〉PubMed〈/a〉
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  • 119
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    Commercial biotechnology (1984)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1984-03-23
    Description: 〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Abelson, P H -- New York, N.Y. -- Science. 1984 Mar 23;223(4642):1253.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/6701523" target="_blank"〉PubMed〈/a〉
    Keywords: *Biological Products ; *Medical Laboratory Science ; *Technology, Pharmaceutical
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  • 120
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    Chemistry without test tubes (1984)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1984-06-22
    Description: 〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Abelson, P H -- New York, N.Y. -- Science. 1984 Jun 22;224(4655):1297.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/17837181" target="_blank"〉PubMed〈/a〉
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  • 121
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    "Nuclear winter" studies (1984)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1984-09-07
    Description: 〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Aleksandrov, V -- New York, N.Y. -- Science. 1984 Sep 7;225(4666):978.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/17783018" target="_blank"〉PubMed〈/a〉
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  • 122
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    Carbohydrate dramatically influences immune reactivity of antisera to viral glycoprotein antigens (1984)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1984-12-14
    Description: Analysis of the ability of heteroantisera, monoclonal antibodies, and antibodies to synthetic peptides to react with viral glycoproteins deglycosylated with endoglycosidase F revealed that the reactivities of most of the antibodies to these glycoprotein antigens were influenced by the attached carbohydrate moieties. All heteroantisera prepared in rabbits or goats to either fully glycosylated retroviruses or influenza virus were virtually unreactive toward the viral glycoproteins after carbohydrate removal. Analyses with a panel of monoclonal antibodies to purified Rauscher murine leukemia virus gp70 indicated that the reactivity of most of these antibodies improved while the reactivity of others decreased or remain unchanged after carbohydrate removal. Most of the antibodies to synthetic peptide sequences in the influenza virus hemagglutinin also improved in reactivity after carbohydrate removal. These data indicate that carbohydrate side chains on viral glycoproteins influence the immune response to these antigens, and the more native the glycoprotein immunogen, the more dramatic the carbohydrate influence. Thus the immune response to these glycoproteins is not simply a function of the immunogenicity of certain domains over others but rather is a direct measure of carbohydrate influences on the host's perception of the foreign antigen.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Alexander, S -- Elder, J H -- CA25533/CA/NCI NIH HHS/ -- CA25803/CA/NCI NIH HHS/ -- New York, N.Y. -- Science. 1984 Dec 14;226(4680):1328-30.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/6505693" target="_blank"〉PubMed〈/a〉
    Keywords: Antibodies, Monoclonal/immunology ; *Antigen-Antibody Reactions ; Antigens, Viral/*immunology ; Carbohydrates/*physiology ; Immune Sera/*immunology ; Orthomyxoviridae/immunology ; Rauscher Virus/immunology ; Viral Proteins/*immunology
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  • 123
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    The East coast magnetic anomaly (1984)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1984-12-07
    Description: A model is proposed for the East Coast Magnetic Anomaly that, for the first time, incorporates an observed basement feature-a normal fault that consistently lies below the landward flank of the anomaly. The East Coast Magnetic Anomaly is similar to slope anomalies found over passive continental margins in many parts of the world. Thus the proposed model can be used to interpret slope anomalies in general.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Alsop, L E -- Talwani, M -- New York, N.Y. -- Science. 1984 Dec 7;226(4679):1189-91.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/17770989" target="_blank"〉PubMed〈/a〉
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    The end of the cretaceous: sharp boundary or gradual transition? (1984)
    American Association for the Advancement of Science (AAAS)
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    Publication Date: 1984-03-16
    Description: Evidence indicates that the Cretaceous-Tertiary boundary is very sharp, and, within the limits of resolution, it is apparently synchronous at the various boundary localities. Arguments to the contrary, particularly those of Officer and Darke, are shown to invalid.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Alvarez, W -- Alvarez, L W -- Asaro, F -- Michel, H V -- New York, N.Y. -- Science. 1984 Mar 16;223(4641):1183-6.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/17742934" target="_blank"〉PubMed〈/a〉
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    Transmission of HTLV-III infection from human plasma to chimpanzees: an animal model for AIDS (1984)
    American Association for the Advancement of Science (AAAS)
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    Publication Date: 1984-11-02
    Description: Two of three chimpanzees given plasma from patients with acquired immune deficiency syndrome (AIDS) or pre-AIDS showed serum antibodies to type III human T-cell leukemia virus (HTLV-III) 10 to 12 weeks after transfusion. One animal also developed lymphadenopathy, transient depression of the ratio of T4 to T8 lymphocytes, and impaired blastogenic responses. No opportunistic infections occurred. Adenopathy persisted for 32 weeks, and antibody to HTLV-III persisted for at least 48 weeks. This transmission of HTLV-III by lymphocyte-poor plasma confirms the potential risk of such plasma or plasma derivatives to recipients. The susceptibility of the chimpanzee to HTLV-III infection and the ability to simulate the human lymphadenopathy syndrome in this animal makes it a valuable model for further study of AIDS.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Alter, H J -- Eichberg, J W -- Masur, H -- Saxinger, W C -- Gallo, R -- Macher, A M -- Lane, H C -- Fauci, A S -- New York, N.Y. -- Science. 1984 Nov 2;226(4674):549-52.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/6093251" target="_blank"〉PubMed〈/a〉
    Keywords: Acquired Immunodeficiency Syndrome/blood/pathology/*transmission ; Animals ; Antibodies, Viral/immunology ; *Deltaretrovirus/immunology ; *Disease Models, Animal ; Humans ; Leukocyte Count ; Lymph Nodes/pathology ; *Pan troglodytes/microbiology ; T-Lymphocytes
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    Calcium-mediated reduction of ionic currents: a biophysical memory trace (1984)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1984-11-30
    Description: Learning behavior similar to vertebrate classical conditioning was demonstrated for the mollusc Hermissenda crassicornis. Postsynaptic membrane changes within well-defined neural systems that mediate the learning play a casual role in recording the learned association for later recall. Specific ionic currents in neural tissue undergo transformations lasting days after associative training with physiologic stimuli. During acquisition the intracellular calcium increases; this increase is accompanied by specific potassium current reduction that lasts for days after conditioning. The increase of calcium enhances calmodulin-dependent phosphorylation of proteins that either regulate or are part of ion channels. These currents and the conditions that precede their transformation occur in many types of vertebrate neurons, and hence this biophysical basis of Hermissenda learning could have relevance for species other than the gastropod studied.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Alkon, D L -- New York, N.Y. -- Science. 1984 Nov 30;226(4678):1037-45.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/6093258" target="_blank"〉PubMed〈/a〉
    Keywords: Animals ; Calcium/*metabolism ; Electric Conductivity ; Ion Channels/*physiology ; *Learning ; *Memory ; Mollusca ; Neurons/physiology ; Ocular Physiological Phenomena ; Potassium/metabolism ; Synapses/physiology
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    Daniel e. Koshland, jr., new editor of science (1984)
    American Association for the Advancement of Science (AAAS)
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    Publication Date: 1984-12-21
    Description: 〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Ames, B N -- New York, N.Y. -- Science. 1984 Dec 21;226(4681):1396-7.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/17788983" target="_blank"〉PubMed〈/a〉
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    Leptospirosis in laboratory mice (1984)
    American Association for the Advancement of Science (AAAS)
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    Publication Date: 1984-06-15
    Description: The obituary for William A. Altemeier, Jr. (4 May, p. 525), was incorrect. Dr. Altemeier was chairman of the Department of Surgery at the University of Cincinnati.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Alexander, A D -- New York, N.Y. -- Science. 1984 Jun 15;224(4654):1158.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/6729449" target="_blank"〉PubMed〈/a〉
    Keywords: Animals ; Animals, Laboratory/*microbiology ; Dogs ; Humans ; Leptospira ; Leptospirosis/*microbiology/transmission ; Mice ; Mice, Inbred ICR ; Primates ; Rats
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    The endocrine system (1984)
    American Association for the Advancement of Science (AAAS)
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    Publication Date: 1984-04-20
    Description: 〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Anctil, M -- New York, N.Y. -- Science. 1984 Apr 20;224(4646):240.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/17734899" target="_blank"〉PubMed〈/a〉
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    Heterochronic mutants of the nematode Caenorhabditis elegans (1984)
    American Association for the Advancement of Science (AAAS)
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    Publication Date: 1984-10-26
    Description: Mutations in the Caenorhabditis elegans genes lin-14, lin-28, and lin-29 cause heterochronic developmental defects: the timing of specific developmental events in several tissues is altered relative to the timing of events in other tissues. These defects result from temporal transformations in the fates of specific cells, that is, certain cells express fates normally expressed by cells generated at other developmental stages. The identification and characterization of genes that can be mutated to cause heterochrony support the proposal that heterochrony is a mechanism for phylogenetic change and suggest cellular and genetic bases for heterochronic variation.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Ambros, V -- Horvitz, H R -- GM24663/GM/NIGMS NIH HHS/ -- GM24943/GM/NIGMS NIH HHS/ -- HD00369/HD/NICHD NIH HHS/ -- etc. -- New York, N.Y. -- Science. 1984 Oct 26;226(4673):409-16.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/6494891" target="_blank"〉PubMed〈/a〉
    Keywords: Animals ; Caenorhabditis/*genetics ; Female ; *Genes ; Genetic Variation ; Male ; *Mutation ; *Phylogeny ; Time Factors
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    The Earth as a planet: paradigms and paradoxes (1984)
    American Association for the Advancement of Science (AAAS)
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    Publication Date: 1984-01-27
    Description: The independent growth of the various branches of the earth sciences in the past two decades has led to a divergence of geophysical, geochemical, geological, and planetological models for the composition and evolution of a terrestrial planet. Evidence for differentiation and volcanism on small planets and a magma ocean on the moon contrasts with hypotheses for a mostly primitive, still undifferentiated, and homogeneous terrestrial mantle. In comparison with the moon, the earth has an extraordinarily thin crust. The geoid, which should reflect convection in the mantle, is apparently unrelated to the current distribution of continents and oceanic ridges. If the earth is deformable, the whole mantle should wander relative to the axis of rotation, but the implications of this are seldom discussed. The proposal of a mantle rich in olivine violates expectations based on evidence from extraterrestrial sources. These and other paradoxes force a reexamination of some long-held assumptions.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Anderson, D L -- New York, N.Y. -- Science. 1984 Jan 27;223(4634):347-55.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/17829875" target="_blank"〉PubMed〈/a〉
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    Bob ormes: an appreciation (1984)
    American Association for the Advancement of Science (AAAS)
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    Publication Date: 1984-08-24
    Description: 〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Altman, P L -- New York, N.Y. -- Science. 1984 Aug 24;225(4664):786.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/17801133" target="_blank"〉PubMed〈/a〉
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    Magnesium deficiency and hypertension: correlation between magnesium-deficient diets and microcirculatory changes in situ (1984)
    American Association for the Advancement of Science (AAAS)
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    Publication Date: 1984-03-23
    Description: Rats maintained for 12 weeks on diets moderately or more severely deficient in magnesium showed significant elevations in arterial blood pressure compared to control animals. Examination of the mesenteric microcirculation in situ revealed that dietary magnesium deficiency resulted in reduced capillary, postcapillary, and venular blood flow concomitant with reduced terminal arteriolar, precapillary sphincter, and venular lumen sizes. The greater the degree of dietary magnesium deficiency the greater the reductions in microvascular lumen sizes. These findings may provide a rationale for the etiology, as well as treatment, of some forms of hypertensive vascular disease.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Altura, B M -- Altura, B T -- Gebrewold, A -- Ising, H -- Gunther, T -- HL18015/HL/NHLBI NIH HHS/ -- HL29600/HL/NHLBI NIH HHS/ -- New York, N.Y. -- Science. 1984 Mar 23;223(4642):1315-7.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/6701524" target="_blank"〉PubMed〈/a〉
    Keywords: Animals ; Arterioles/pathology ; *Blood Pressure ; Capillaries/pathology ; Magnesium/blood ; Magnesium Deficiency/pathology/*physiopathology ; Male ; *Microcirculation ; Rats ; Rats, Inbred Strains ; *Vasoconstriction ; Venules/pathology
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    In reply: cancer and diet (1984)
    American Association for the Advancement of Science (AAAS)
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    Publication Date: 1984-05-18
    Description: 〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Ames, B N -- New York, N.Y. -- Science. 1984 May 18;224(4650):668-760.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/17780577" target="_blank"〉PubMed〈/a〉
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    Impact theory of mass extinctions and the invertebrate fossil record (1984)
    American Association for the Advancement of Science (AAAS)
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    Publication Date: 1984-03-16
    Description: There is much evidence that the Cretaceous-Tertiary boundary was marked by a massive meteorite impact. Theoretical consideration of the consquences of such an impact predicts sharp extinctions in many groups of animals precisely at the boundary. Paleontological data clearly show gradual declines in diversity over the last 1 to 10 million years in various invertebrate groups.Reexamination of data from careful studies of the best sections shows that, in addition to undergoing the decline, four groups (ammonites, cheilostomate beyozoans, brachiopods, and bivalves) were affected by sudden truncations precisely at the iridium anomaly that marks the boundary. The paleontological record thus bears witness to terminal-Cretaceous extinctions on two time scales: a slow decline unrelated to the impact and a sharp truncation synchronous with and probably caused by the impact.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Alvarez, W -- Kauffman, E G -- Surlyk, F -- Alvarez, L W -- Asaro, F -- Michel, H V -- New York, N.Y. -- Science. 1984 Mar 16;223(4641):1135-41.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/17742919" target="_blank"〉PubMed〈/a〉
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    Gene therapy researchers (1984)
    American Association for the Advancement of Science (AAAS)
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    Publication Date: 1984-04-27
    Description: 〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Anderson, W F -- New York, N.Y. -- Science. 1984 Apr 27;224(4647):340.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/17741202" target="_blank"〉PubMed〈/a〉
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    Gas reactors (1984)
    American Association for the Advancement of Science (AAAS)
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    Publication Date: 1984-06-29
    Description: 〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Anderson, C A Jr -- New York, N.Y. -- Science. 1984 Jun 29;224(4656):1382.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/17793355" target="_blank"〉PubMed〈/a〉
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    Astronomy and Solar Physics: X-ray Gas Scintillation Spectrometer Experiment (1984)
    American Association for the Advancement of Science (AAAS)
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    Publication Date: 1984-07-13
    Description: The payload complement on Spacelab 1 included a spectrometer for observations of the brighter cosmic x-ray sources. The primary scientific objective was to study the detailed spectral features of cosmic x-ray sources and their associated temporal variations over a wide energy range from about 2 to 80 kiloelectron volts. The instrument, based on the gas scintillation proportional counter, had a geometrical area of some 180 square centimeters with an energy resolution of about 9 percent at 7 kiloelectron volts. The results presented here show new results from two galactic binary x-ray sources, Cygnus X-3 and Centaurus X-3, and from the Perseus cluster of galaxies. The excellent energy resolution of the instrument permits line features to be identified in these sources with unprecedented quality.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Andresen, R D -- Boella, G -- Falconi, B -- Lamb, P -- Manzo, G -- Raymont, J -- Re, S -- Sims, M R -- Villa, G -- New York, N.Y. -- Science. 1984 Jul 13;225(4658):177-9.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/17837931" target="_blank"〉PubMed〈/a〉
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    The new refuseniks (1984)
    American Association for the Advancement of Science (AAAS)
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    Publication Date: 1984-05-25
    Description: 〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Anfinsen, C -- Axelrod, J -- Gottesman, M -- Plotz, P -- New York, N.Y. -- Science. 1984 May 25;224(4651):794.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/17743180" target="_blank"〉PubMed〈/a〉
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    Sinking of volcanic ash in uncompacted sediment in williams lake, washington (1984)
    American Association for the Advancement of Science (AAAS)
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    Publication Date: 1984-08-03
    Description: Volcanic ash from the eruption of Mount St. Helens on 18 May 1980 fell into Williams Lake in eastern Washington and was temporarily suspended at the sediment-water interface. After several months of compaction, the ash layer broke up and sank into lower density uncompacted lake sediment. Stratigraphic time displacements of several hundred years and a failure to recognize discontinuous ash layers in sediment cores are possible consequences of this process.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Anderson, R Y -- Nuhfer, E B -- Dean, W E -- New York, N.Y. -- Science. 1984 Aug 3;225(4661):505-8.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/17750852" target="_blank"〉PubMed〈/a〉
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    Molecular indices of cell lineage specification in sea urchin embryos (1984)
    American Association for the Advancement of Science (AAAS)
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    Publication Date: 1984-12-07
    Description: The origins of several of the differentiated cell lineages of the advanced sea urchin embryo are well defined. Cytological application of molecular probes to three lineages, those responsible for the formation of the skeleton, the gut, and the aboral ectodermal wall of the late embryo, has demonstrated expression of lineage-specific genes long before overt morphological differentiation. These observations lead to useful generalizations regarding the processes of gene regulation that underlie the molecular biology of cell lineage specification in the embryo.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Angerer, R C -- Davidson, E H -- GM-25553/GM/NIGMS NIH HHS/ -- HD-05753/HD/NICHD NIH HHS/ -- New York, N.Y. -- Science. 1984 Dec 7;226(4679):1153-60.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/6594757" target="_blank"〉PubMed〈/a〉
    Keywords: Actins/genetics ; Animals ; Blastomeres/physiology ; Calcium-Binding Proteins/genetics ; *Cell Differentiation ; Cytoplasm/physiology ; Ectoderm/physiology ; *Gene Expression Regulation ; Genetic Markers ; Germ Layers/physiology ; Intestines/embryology ; Morphogenesis ; RNA, Messenger/metabolism ; Sea Urchins/*embryology
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    Cytochrome a3 structure in carbon monoxide-bound cytochrome oxidase (1984)
    American Association for the Advancement of Science (AAAS)
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    Publication Date: 1984-07-20
    Description: The iron-carbon monoxide stretching mode and the iron-carbon-oxygen bending mode in carbon monoxide-bound cytochrome oxidase have been assigned at 520 and 578 cm-1, respectively. The frequencies, widths, and intensities of these modes show that the Fe-C-O grouping in carbon monoxide-cytochrome a3 is linear but tilted from the normal to the heme plane; that the iron-histidine bond in both five- and six-coordinate cytochrome a3 is strained; and that the carbon monoxide and the proximal histidine each have characteristic, well-defined orientations in all molecules. These data can account for the binding affinities of carbon monoxide and dioxygen under physiological conditions.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Argade, P V -- Ching, Y C -- Rousseau, D L -- New York, N.Y. -- Science. 1984 Jul 20;225(4659):329-31.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/6330890" target="_blank"〉PubMed〈/a〉
    Keywords: Animals ; Carbon Monoxide/metabolism ; Cattle ; Chemical Phenomena ; Chemistry ; Electron Transport Complex IV/*metabolism ; Myoglobin/metabolism ; Oxidation-Reduction ; Oxygen/metabolism ; Spectrum Analysis, Raman
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    Computer-based instructional dialogs in science courses (1984)
    American Association for the Advancement of Science (AAAS)
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    Publication Date: 1984-06-08
    Description: The personal computer is opening the door to supplemental, essentially tutorial, modes of science instruction that, particularly at introductory levels, can significantly enhance understanding of science and develop abstract reasoning skills. Competently prepared and judiciously utilized materials have the potential to improve the education of science and engineering professionals, elementary and secondary teachers, and, to some degree, the public at large.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Arons, A B -- New York, N.Y. -- Science. 1984 Jun 8;224(4653):1051-6.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/17735229" target="_blank"〉PubMed〈/a〉
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    Prospects for human gene therapy (1984)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1984-10-26
    Description: Procedures have now been developed for inserting functional genes into the bone marrow of mice. The most effective delivery system at present uses retroviral-based vectors to transfer a gene into murine bone marrow cells in culture. The genetically altered bone marrow is then implanted into recipient animals. These somatic cell gene therapy techniques are becoming increasingly efficient. Their future application in humans should result in at least partial correction of a number of genetic disorders. However, the safety of the procedures must still be established by further animal studies before human clinical trials would be ethical.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Anderson, W F -- New York, N.Y. -- Science. 1984 Oct 26;226(4673):401-9.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/6093246" target="_blank"〉PubMed〈/a〉
    Keywords: Animal Experimentation ; Bone Marrow ; Containment of Biohazards ; DNA Viruses/genetics ; *DNA, Recombinant ; Ethics Committees, Research ; Ethics, Medical ; Federal Government ; Gene Expression Regulation ; *Genes ; Genetic Diseases, Inborn/*therapy ; *Genetic Engineering ; Genetic Vectors ; Government Regulation ; Humans ; Microinjections ; Operon ; Plasmids ; Retroviridae/genetics ; Risk Assessment ; Skin ; Transcription, Genetic ; future clinical trials in humans are being debated among scientists and policy ; makers. Anderson, chief of the Laboratory of Molecular Hematology at the National ; Heart, Lung, and Blood Institute, examines how soon gene therapy might be ; available for the treatment of diseases in humans, and what criteria should be ; met before experimentation with human subjects begins. He identifies delivery, ; gene expression, and safety as the three requisites that must be satisfied, and ; reviews the animal work that has been done in these areas. Human trials should ; begin only after more animal studies have demonstrated to local and federal ; review committees that gene therapy is safe and offers the possibility of benefit ; to patients.
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    Task-relevant late positive component of the auditory event-related potential in monkeys resembles P300 in humans (1984)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1984-01-13
    Description: A long-latency (300-millisecond), vertex-positive component of the event-related potential recorded from monkeys was present only when the eliciting stimulus was relevant to the task. The amplitude of this component varied inversely with stimulus probability and was dissociable from motor responses.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Arthur, D L -- Starr, A -- MH14599-06/MH/NIMH NIH HHS/ -- NS11876-08/NS/NINDS NIH HHS/ -- New York, N.Y. -- Science. 1984 Jan 13;223(4632):186-8.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/6691145" target="_blank"〉PubMed〈/a〉
    Keywords: Acoustic Stimulation ; Animals ; Electroencephalography ; Electrooculography ; *Evoked Potentials, Auditory ; Humans ; Macaca nemestrina ; Probability
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    Formaldehyde risk assessment (1984)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1984-06-08
    Description: 〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Ashford, N A -- Ryan, C W -- Caldart, C C -- Hattis, D -- New York, N.Y. -- Science. 1984 Jun 8;224(4653):1128.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/17735248" target="_blank"〉PubMed〈/a〉
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    Formaldehyde regulation (1984)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1984-05-11
    Description: 〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Ashford, N A -- Ryan, C W -- Caldart, C C -- Hattis, D -- New York, N.Y. -- Science. 1984 May 11;224(4649):554-6.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/17838339" target="_blank"〉PubMed〈/a〉
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    A botanical explorer: frank N. Meyer (1984)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1984-09-14
    Description: 〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Ashton, P -- New York, N.Y. -- Science. 1984 Sep 14;225(4667):1140-1.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/17782414" target="_blank"〉PubMed〈/a〉
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  • 149
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    Rapid expulsion of Trichinella spiralis in suckling rats (1984)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1984-10-05
    Description: Orally administered Trichinella spiralis muscle larvae were rapidly expelled by rat pups suckling an immune dam. The immunity was delivered in the milk; substantial resistance was conferred on normal rat pups suckled for only 24 hours by a Trichinella-immune foster mother. The pups were protected by oral or systemic administration of specific serum antibodies. When infused into a normal lactating dam, these antibodies accumulated in the serum of her suckling pups.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Appleton, J A -- McGregor, D D -- AI 14490/AI/NIAID NIH HHS/ -- New York, N.Y. -- Science. 1984 Oct 5;226(4670):70-2.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/6474191" target="_blank"〉PubMed〈/a〉
    Keywords: Animals ; Animals, Suckling ; Antibodies/immunology ; Colostrum/immunology ; Female ; *Immunity, Maternally-Acquired ; Immunization, Passive ; Intestinal Diseases, Parasitic/*immunology/parasitology ; Intestinal Mucosa/parasitology ; Milk/*immunology ; Rats ; Trichinella/*immunology/physiology ; Trichinellosis/*immunology/parasitology
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    Susceptibility of skeletal muscle to Coxsackie A2 virus infection: effects of botulinum toxin and denervation (1984)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1984-02-17
    Description: Coxsackie A viruses can infect denervated but not innervated mature skeletal muscles. The role of synaptic transmission in preventing susceptibility to Coxsackievirus infection was studied by surgically denervating leg muscles of mice or injecting the muscles with botulinum toxin to block quantal release of acetylcholine. Control muscles were injected with heat-inactivated toxin. Subsequent injection of Coxsackie A2 virus resulted in extensive virus replication and tissue destruction in the denervated and botulinum toxin-treated muscles, while the control muscles showed only minimal changes. This suggests that the susceptibility of skeletal muscle to Coxsackievirus infection is regulated by synaptic transmission.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Andrew, C G -- Drachman, D B -- Pestronk, A -- Narayan, O -- 5 K07 NS 00531-02/NS/NINDS NIH HHS/ -- 5R01 HD04817/HD/NICHD NIH HHS/ -- New York, N.Y. -- Science. 1984 Feb 17;223(4637):714-6.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/6320369" target="_blank"〉PubMed〈/a〉
    Keywords: Animals ; Botulinum Toxins/*pharmacology ; Coxsackievirus Infections/*microbiology ; Enterovirus/*pathogenicity ; Mice ; *Muscle Denervation ; Muscles/drug effects/microbiology ; Muscular Diseases/*microbiology ; Sciatic Nerve/physiology
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    Native cellulose: a composite of two distinct crystalline forms (1984)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1984-01-20
    Description: Multiplicities in the resonances of chemically equivalent carbons, which appear in the solid-state carbon-13 nuclear magnetic resonance spectra of native celluloses, have been examined at high resolution. The patterns of variation are consistent with the existence of two distinct crystalline forms. One form is dominant in bacterial and algal celluloses, whereas the other is dominant in celluloses from higher plants.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Atalla, R H -- Vanderhart, D L -- New York, N.Y. -- Science. 1984 Jan 20;223(4633):283-5.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/17801599" target="_blank"〉PubMed〈/a〉
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    Inhibition of aldosterone production by an atrial extract (1984)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1984-06-01
    Description: Crude extracts of rat atria reduced the basal amount of aldosterone released from rat zona glomerulosa cells and partially inhibited aldosterone stimulation by adrenocorticotropic hormone and angiotensin II. The destruction of this activity by trypsin suggests that the active factor is a peptide, possibly atrial natriuretic factor. These data suggest that atrial natriuretic factor affects sodium excretion by the kidneys both directly and through the inhibition of aldosterone production.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Atarashi, K -- Mulrow, P J -- Franco-Saenz, R -- Snajdar, R -- Rapp, J -- New York, N.Y. -- Science. 1984 Jun 1;224(4652):992-4.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/6326267" target="_blank"〉PubMed〈/a〉
    Keywords: Adrenocorticotropic Hormone/pharmacology ; Aldosterone/*biosynthesis ; Angiotensin II/pharmacology ; Animals ; *Atrial Function ; Dogs ; Female ; Kidney/drug effects/metabolism ; Mineralocorticoid Receptor Antagonists/pharmacology ; Natriuresis/drug effects ; Rats ; Rats, Inbred Strains ; Trypsin/pharmacology
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    Education for an age of science (1984)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1984-03-30
    Description: 〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Atkinson, R C -- New York, N.Y. -- Science. 1984 Mar 30;223(4643):1355.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/17746038" target="_blank"〉PubMed〈/a〉
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    Neuroscience advances (1984)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1984-09-21
    Description: 〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Axelrod, J -- New York, N.Y. -- Science. 1984 Sep 21;225(4668):1253.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/6474174" target="_blank"〉PubMed〈/a〉
    Keywords: Animals ; Humans ; *Neurology
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    Salivary proline-rich protein genes on chromosome 8 of mouse (1984)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1984-11-23
    Description: Endonuclease restriction (Hind III) fragments of DNA from Chinese hamster X mouse somatic cell hybrids hybridized with proline-rich protein complementary DNA clones only when the DNA was isolated from cells containing mouse chromosome 8, or a fragment of chromosome 8. The evidence suggests that proline-rich protein genes are located at the proximal portion of chromosome 8 toward the centromere.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Azen, E A -- Carlson, D M -- Clements, S -- Lalley, P A -- Vanin, E -- AM 19175/AM/NIADDK NIH HHS/ -- DEO 3658-19/DE/NIDCR NIH HHS/ -- GM 20069/GM/NIGMS NIH HHS/ -- New York, N.Y. -- Science. 1984 Nov 23;226(4677):967-9.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/6095444" target="_blank"〉PubMed〈/a〉
    Keywords: Animals ; Chromosome Mapping ; DNA Restriction Enzymes ; *Genes ; Humans ; Mice ; Mice, Inbred Strains ; Nucleic Acid Hybridization ; Peptides/*genetics ; Proline-Rich Protein Domains ; Protein Biosynthesis ; RNA, Messenger/genetics ; Salivary Proteins and Peptides/*genetics ; Species Specificity
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    Stress hormones: their interaction and regulation (1984)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1984-05-04
    Description: Stress stimulates several adaptive hormonal responses. Prominent among these responses are the secretion of catecholamines from the adrenal medulla, corticosteroids from the adrenal cortex, and adrenocorticotropin from the anterior pituitary. A number of complex interactions are involved in the regulation of these hormones. Glucocorticoids regulate catecholamine biosynthesis in the adrenal medulla and catecholamines stimulate adrenocorticotropin release from the anterior pituitary. In addition, other hormones, including corticotropin-releasing factor, vasoactive intestinal peptide, and arginine vasopressin stimulate while the corticosteroids and somatostatin inhibit adrenocorticotropin secretion. Together these agents appear to determine the complex physiologic responses to a variety of stressors.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Axelrod, J -- Reisine, T D -- New York, N.Y. -- Science. 1984 May 4;224(4648):452-9.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/6143403" target="_blank"〉PubMed〈/a〉
    Keywords: Adenylyl Cyclases/metabolism ; Adrenal Cortex/metabolism ; Adrenal Medulla/metabolism ; Adrenocorticotropic Hormone/*metabolism ; Animals ; Brain/metabolism ; Catecholamines/*metabolism ; Cell Line ; Corticotropin-Releasing Hormone/metabolism ; Cyclic AMP/metabolism ; Glucocorticoids/*metabolism ; Humans ; Phospholipases A/metabolism ; Pituitary Gland, Anterior/metabolism ; Receptors, Adrenergic, alpha/metabolism ; Receptors, Adrenergic, beta/metabolism ; Receptors, Cell Surface/metabolism ; Receptors, Corticotropin-Releasing Hormone ; Receptors, Somatostatin ; Somatostatin/pharmacology ; Stress, Physiological/*metabolism ; Stress, Psychological/metabolism ; Sympathetic Nervous System/metabolism ; Vasoactive Intestinal Peptide/pharmacology ; Vasopressins/pharmacology
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    Regulation of a hybrid gene by glucose and temperature in hamster fibroblasts (1984)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1984-10-12
    Description: A novel eukaryotic hybrid gene has been constructed from the 5' sequence of a rat gene and the bacterial neomycin-resistance gene. After transfection into hamster fibroblasts, the neo transcripts can be induced to high levels by the absence of glucose. Furthermore, this hybrid gene can be regulated by temperature when it is introduced into a temperature-sensitive mutant cell line.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Attenello, J W -- Lee, A S -- CA-27607/CA/NCI NIH HHS/ -- New York, N.Y. -- Science. 1984 Oct 12;226(4671):187-90.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/6484570" target="_blank"〉PubMed〈/a〉
    Keywords: Animals ; Cell Line ; Cricetinae ; DNA, Recombinant ; Drug Resistance, Microbial ; Fibroblasts ; *Gene Expression Regulation ; Genes, Bacterial ; *Genes, Regulator ; Glucose/*pharmacology ; *HSP70 Heat-Shock Proteins ; Membrane Proteins/biosynthesis/*genetics ; Mutation ; Neomycin/pharmacology ; Rats ; Temperature ; Transcription, Genetic ; Transfection
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    The standardization of manufacturing: from the american system to mass production, 1800-1932 (1984)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1984-10-19
    Description: 〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Atack, J -- New York, N.Y. -- Science. 1984 Oct 19;226(4672):331-2.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/17749881" target="_blank"〉PubMed〈/a〉
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  • 159
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    Trace elements in tree rings: evidence of recent and historical air pollution (1984)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1984-05-04
    Description: Annual growth rings from short-leaf pine trees in the Great Smoky Mountains National Park show suppressed growth and increased iron content between 1863 and 1912, a period of smelting activity and large sulfur dioxide releases at Copperhill, Tennessee, 88 kilometers upwind. Similar growth suppression and increases of iron and other metals were found in rings formed in the past 20 to 25 years, a period when regional fossil fuel combustion emissions increased about 200 percent. Metals concentrations in phloem and cambium are high, but whether they exceed toxic thresholds for these tissues is not known.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Baes, C F 3rd -- McLaughlin, S B -- New York, N.Y. -- Science. 1984 May 4;224(4648):494-7.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/17753775" target="_blank"〉PubMed〈/a〉
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    Raman spectroscopy of a coal liquid shows that fluorescence interference is minimized with ultraviolet excitation (1984)
    American Association for the Advancement of Science (AAAS)
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    Publication Date: 1984-07-20
    Description: The first ultraviolet resonance Raman measurements of a coal liquid are reported. The spectra detail the presence of numerous polycyclic aromatic hydrocarbons with ring systems similar to those of naphthalene, fluorene, phenanthrene, pyrene, and triphenylene . The ultraviolet resonance Raman measurements of this highly complex sample show no significant interference from fluorescence. The lack of fluorescence interference and the high selectivity indicate that ultraviolet resonance Raman spectroscopy is a powerful new technique for characterizing highly complex samples and mixtures.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Asher, S A -- Johnson, C R -- 1R01 GM 30741-01/GM/NIGMS NIH HHS/ -- New York, N.Y. -- Science. 1984 Jul 20;225(4659):311-3.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/6740313" target="_blank"〉PubMed〈/a〉
    Keywords: Coal/*analysis ; Fluorescence ; Polycyclic Compounds/analysis ; *Spectrum Analysis, Raman ; Ultraviolet Rays
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    T-cell growth factor gene: lack of expression in human T-cell leukemia-lymphoma virus-infected cells (1984)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1984-03-09
    Description: Activated mature T cells require T-cell growth factor (TCGF) for continuous proliferation. However, many mature T cells infected with human T-cell leukemia-lymphoma virus grow independently of exogenously added TCGF. It is now reported that cells infected with this virus also lack detectable TCGF messenger RNA (less than one copy per cell) and thus do not produce their own growth factor. The results apparently rule out an autostimulation mechanism of growth control.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Arya, S K -- Wong-Staal, F -- Gallo, R C -- New York, N.Y. -- Science. 1984 Mar 9;223(4640):1086-7.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/6320374" target="_blank"〉PubMed〈/a〉
    Keywords: Cell Line ; Deltaretrovirus/*physiology ; *Gene Expression Regulation/drug effects ; Humans ; Interferon-gamma/genetics ; Interleukin-2/*genetics ; Phytohemagglutinins/pharmacology ; RNA, Messenger/*genetics ; T-Lymphocytes/metabolism/*microbiology ; Tetradecanoylphorbol Acetate/pharmacology
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  • 162
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    Homology of genome of AIDS-associated virus with genomes of human T-cell leukemia viruses (1984)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1984-08-31
    Description: A T lymphotropic virus found in patients with the acquired immune deficiency syndrome (AIDS) or lymphadenopathy syndrome has been postulated to be the cause of AIDS. Immunological analysis of this retrovirus and its biological properties suggest that it is a member of the family of human T-lymphotropic retroviruses known as HTLV. Accordingly, it has been named HTLV-III. In the present report it is shown by nucleic acid hybridization that sequences of the genome of HTLV-III are homologous to the structural genes (gag, pol, and env) of both HTLV-I and HTLV-II and to a potential coding region called pX located between the env gene and the long terminal repeating sequence that is unique to the HTLV family of retroviruses.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Arya, S K -- Gallo, R C -- Hahn, B H -- Shaw, G M -- Popovic, M -- Salahuddin, S Z -- Wong-Staal, F -- New York, N.Y. -- Science. 1984 Aug 31;225(4665):927-30.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/6089333" target="_blank"〉PubMed〈/a〉
    Keywords: Acquired Immunodeficiency Syndrome/*microbiology ; Base Sequence ; Cloning, Molecular ; Dna ; DNA, Viral ; Deltaretrovirus/classification/*genetics ; Genes ; *Genes, Viral ; Humans ; *Nucleic Acid Hybridization ; RNA, Viral ; Repetitive Sequences, Nucleic Acid
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    Growth self-incitement in murine melanoma B16: a phenomenological model (1984)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1984-08-31
    Description: The growing murine melanoma B16 secretes increasing quantities of a substance or substances immunologically cross-reactive with insulin. The elevated concentrations of these substances in blood are accompanied by a decrease in blood glucose concentration and release of growth hormone, which is followed by increased tumor growth. By use of a phenomenological model based on these data, we show that B16 incites its own growth by positive feedback.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Bajzer, Z -- Pavelic, K -- Vuk-Pavlovic, S -- New York, N.Y. -- Science. 1984 Aug 31;225(4665):930-2.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/6382606" target="_blank"〉PubMed〈/a〉
    Keywords: Animals ; Blood Glucose/*analysis ; Growth Hormone/blood ; Insulin/blood/*secretion ; Male ; Mathematics ; Melanoma/blood/pathology/*secretion ; Mice ; Mice, Inbred C57BL ; Models, Biological
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    SWARM Meets in Lubbock (1984)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1984-05-04
    Description: 〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Balcomb, M M -- New York, N.Y. -- Science. 1984 May 4;224(4648):482-3.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/17753763" target="_blank"〉PubMed〈/a〉
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    Fibrinogen and fibrin: molecular biology of fibrinogen and fibrin (1984)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1984-04-06
    Description: 〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Bang, N U -- New York, N.Y. -- Science. 1984 Apr 6;224(4644):52-3.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/17783519" target="_blank"〉PubMed〈/a〉
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    Soviet science (1984)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1984-05-04
    Description: 〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Bard, A J -- New York, N.Y. -- Science. 1984 May 4;224(4648):446.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/17753748" target="_blank"〉PubMed〈/a〉
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  • 167
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    Chromosomal location of human T-cell receptor gene Ti beta (1984)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1984-10-19
    Description: A complementary DNA probe corresponding to the beta-chain gene of Ti, the human T lymphocyte receptor, has been molecularly cloned. The chromosomal origin of the Ti beta gene was determined with the complementary DNA by screening a series of 12 cell hybrid (mouse X human) DNA's containing overlapping subsets of human chromosomes. DNA hybridization (Southern) experiments showed that the human Ti beta gene resides on chromosome 7 and is thus not linked to the immunoglobulin loci or to the major histocompatibility locus in humans.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Barker, P E -- Ruddle, F H -- Royer, H D -- Acuto, O -- Reinherz, E L -- AI 21226/AI/NIAID NIH HHS/ -- GM-09966/GM/NIGMS NIH HHS/ -- R0 1 AI 19807/AI/NIAID NIH HHS/ -- New York, N.Y. -- Science. 1984 Oct 19;226(4672):348-9.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/6435246" target="_blank"〉PubMed〈/a〉
    Keywords: Animals ; Chromosome Mapping ; *Chromosomes, Human, 6-12 and X ; Cloning, Molecular ; Dna ; *Genes ; Genetic Linkage ; Humans ; Hybrid Cells ; Immunoglobulin kappa-Chains/genetics ; Major Histocompatibility Complex ; Mice ; Nucleic Acid Hybridization ; Receptors, Antigen, T-Cell/*genetics
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    Late miocene vegetational and climatic variations inferred from a pollen record in northwest wyoming (1984)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1984-01-06
    Description: A pollen stratigraphy from late Miocene lacustrine strata (Teewinot Formation) in Jackson Hole, Wyoming, permits analysis of vegetation and climate history over a time interval of less than 300,000 years with better temporal resolution of data than has been reported from terrestrial Tertiary deposits. The flora was essentially modern, and six successive pollen assemblages indicate alternating dry and wet conditions. The frequency of climatic change in this record is similar to that inferred from marine isotope records for both late Tertiary and Quaternary time.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Barnosky, C W -- New York, N.Y. -- Science. 1984 Jan 6;223(4631):49-51.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/17752988" target="_blank"〉PubMed〈/a〉
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    Soluble lectins (1984)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1984-08-10
    Description: 〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Barondes, S H -- New York, N.Y. -- Science. 1984 Aug 10;225(4662):568.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/17729830" target="_blank"〉PubMed〈/a〉
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  • 170
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    Soluble lectins: a new class of extracellular proteins (1984)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1984-03-23
    Description: Soluble lectins of cellular slime molds and vertebrates are present at extracellular sites in the developing or adult tissues that make them. Some lectins are concentrated around cell groups, as in extracellular matrix or elastic fibers. Others are at the interface between cells and the external environment, as in mucin or slime. Specific glycoproteins, proteoglycans, or polysaccharides that bind these endogenous lectins may also be present at these sites. Interactions between the lectins and glycoconjugates appear to play a role in shaping extracellular environments.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Barondes, S H -- New York, N.Y. -- Science. 1984 Mar 23;223(4642):1259-64.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/6367039" target="_blank"〉PubMed〈/a〉
    Keywords: Adhesiveness ; Animals ; Dictyostelium/physiology ; Embryo, Nonmammalian/metabolism ; Extracellular Matrix/metabolism ; Fungal Proteins/analysis/metabolism/*physiology ; Galactosides/metabolism ; Glycoproteins/metabolism ; Intestines/metabolism ; *Lectins/analysis ; Ligands ; Liver/metabolism ; Macromolecular Substances ; Muscles/metabolism ; Polysaccharides/metabolism ; Proteoglycans/metabolism ; *Protozoan Proteins ; Receptors, Mitogen/metabolism ; Solubility
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  • 171
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    The spiracular organ of sharks and skates: anatomical evidence indicating a mechanoreceptive role (1984)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1984-11-23
    Description: The elasmobranch spiracular organ is a specialized receptor associated with the first visceral pouch. The structure of the sensory epithelium of the spiracular organ and the pattern of central termination of the afferent neurons that innervate it show that the spiracular organ is a mechanoreceptor closely related to the lateral line system of sense organs. Its position and orientation within the spiracular cleft suggest that it plays a role in proprioception or equilibrium-audition.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Barry, M A -- Boord, R L -- NS 11272/NS/NINDS NIH HHS/ -- New York, N.Y. -- Science. 1984 Nov 23;226(4677):990-2.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/6505680" target="_blank"〉PubMed〈/a〉
    Keywords: Afferent Pathways/anatomy & histology ; Animals ; Fishes/*anatomy & histology ; Mechanoreceptors/*physiology/ultrastructure ; Microscopy, Electron, Scanning ; Sharks/*anatomy & histology ; Species Specificity
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    Fast and slow magnetic phenomena in focal epileptic seizures (1984)
    American Association for the Advancement of Science (AAAS)
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    Publication Date: 1984-11-16
    Description: The magnetic fields associated with penicillin-induced focal epilepsy were measured in laboratory rats. Interictal magnetic spikes were similar to those previously observed in humans with focal seizure disorders. The magnetic fields of the seizure itself displayed both slow and fast phenomena, reversing in direction on opposite sides of the head.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Barth, D S -- Sutherling, W -- Beatty, J -- 1-R01-NS20806-01/NS/NINDS NIH HHS/ -- 1K07NS00678-01A1/NS/NINDS NIH HHS/ -- 5-S07 RR07009/RR/NCRR NIH HHS/ -- New York, N.Y. -- Science. 1984 Nov 16;226(4676):855-7.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/6436979" target="_blank"〉PubMed〈/a〉
    Keywords: Animals ; Electroencephalography ; *Electromagnetic Fields ; *Electromagnetic Phenomena ; Electrophysiology ; Epilepsies, Partial/*physiopathology ; Humans ; Penicillins/pharmacology ; Rats ; Rats, Inbred Strains ; Seizures/physiopathology
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  • 173
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    Neuromagnetic evidence of spatially distributed sources underlying epileptiform spikes in the human brain (1984)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1984-01-20
    Description: Neuromagnetic measurements were performed on 17 subjects with focal seizure disorders. In all of the subjects, the interictal spike in the scalp electroencephalogram was associated with an orderly extracranial magnetic field pattern. In eight of these subjects, multiple current sources underlay the magnetic spike complex. The multiple sources within a given subject displayed a fixed chronological sequence of discharge, demonstrating a high degree of spatial and temporal organization within the interictal focus.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Barth, D S -- Sutherling, W -- Engle, J Jr -- Beatty, J -- 5-S07 RR07009/RR/NCRR NIH HHS/ -- 78040-29867-5/PHS HHS/ -- New York, N.Y. -- Science. 1984 Jan 20;223(4633):293-6.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/6422552" target="_blank"〉PubMed〈/a〉
    Keywords: Brain/*physiopathology ; Electroencephalography ; Epilepsies, Partial/*physiopathology ; Humans ; Magnetics
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    Autoantibodies to a 64-kilodalton islet cell protein precede the onset of spontaneous diabetes in the BB rat (1984)
    American Association for the Advancement of Science (AAAS)
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    Publication Date: 1984-06-22
    Description: Spontaneous insulin-dependent diabetes mellitus (IDDM) in the BB rat is associated with the presence of antibodies to a 64-kilodalton rat islet cell protein. These protein antibodies appeared in young animals and remained for as long as 8 weeks before the clinical onset of IDDM. Antibodies to a 64-kilodalton human islet cell protein were found to be associated with human IDDM. Detection of the antibodies may therefore be used to predict an early immune reaction against pancreatic B cells.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Baekkeskov, S -- Dyrberg, T -- Lernmark, A -- AM26190/AM/NIADDK NIH HHS/ -- New York, N.Y. -- Science. 1984 Jun 22;224(4655):1348-50.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/6374896" target="_blank"〉PubMed〈/a〉
    Keywords: Animals ; Autoantibodies/*immunology ; Diabetes Mellitus, Experimental/*immunology ; Diabetes Mellitus, Type 1/immunology ; Humans ; Islets of Langerhans/*immunology ; Rats ; Rats, Inbred Strains ; Rats, Mutant Strains
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    The malaria parasite monitored by photoacoustic spectroscopy (1984)
    American Association for the Advancement of Science (AAAS)
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    Publication Date: 1984-02-24
    Description: Noninvasive photoacoustic spectroscopy was used to study the malaria parasites Plasmodium chabaudi and Plasmodium berghei, their pigment, and ferriprotoporphyrin IX, which is a by-product of the hemoglobin that the parasite ingests. The results indicate that the pigment consists of ferriprotophorphyrin self-aggregates and a noncovalent complex of ferriprotoporphyrin and protein. Spectra of chloroquine-treated parasites reveal in situ interaction between the drug and ferriprotoporphyrin. Chloroquine-resistant parasites, readily distinguishable by this method, appear to degrade hemoglobin only partially.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Balasubramanian, D -- Mohan Rao, C -- Panijpan, B -- New York, N.Y. -- Science. 1984 Feb 24;223(4638):828-30.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/6695185" target="_blank"〉PubMed〈/a〉
    Keywords: Animals ; Chloroquine/pharmacology ; Drug Resistance ; Erythrocytes/*parasitology ; Hemeproteins/metabolism ; Hemin/metabolism ; Hemoglobins/metabolism ; Mice ; Plasmodium/*physiology ; Protoporphyrins/metabolism ; Spectrum Analysis/*methods
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    The 1984 morgan hill, california, earthquake (1984)
    American Association for the Advancement of Science (AAAS)
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    Publication Date: 1984-07-20
    Description: The Morgan Hill, California, earthquake (magnitude 6.1) of 24 April 1984 ruptured a 30-kilometer-long segment of the Calaveras fault zone to the east of San Jose. Although it was recognized in 1980 that an earthquake of magnitude 6 occurred on this segment in 1911 and that a repeat of this event might reasonably be expected, no short-term precursors were noted and so the time of the 1984 earthquake was not predicted. Unilateral rupture propagation toward the south-southeast and an energetic late source of seismic radiation located near the southeast end of the rupture zone contributed to the highly focused pattern of strong motion, including an exceptionally large horizontal acceleration of 1.29g at a site on a dam abutment near the southeast end of the rupture zone.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Bakun, W H -- Clark, M M -- Cockerham, R S -- Ellsworth, W L -- Lindh, A G -- Prescott, W H -- Shakal, A F -- Spudich, P -- New York, N.Y. -- Science. 1984 Jul 20;225(4659):288-91.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/17749545" target="_blank"〉PubMed〈/a〉
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    Residential firewood use (1984)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1984-02-17
    Description: 〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Bailey, M R -- New York, N.Y. -- Science. 1984 Feb 17;223(4637):716-7.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/6695180" target="_blank"〉PubMed〈/a〉
    Keywords: Air Pollution ; *Fires ; Humans ; United States ; *Wood
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    Ionospheric sporadic-e parameters: long-term trends (1984)
    American Association for the Advancement of Science (AAAS)
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    Publication Date: 1984-08-24
    Description: The results of observations over 3(1/2) solar cycles of ionosonde parameters describing sporadic-E patches (E(s)) are given for two Southern Hemisphere stations. Analysis has revealed systematic changes in the occurrence probabilities of f(o)E(s) and f(b)E(s), changes that are independent of time of day or season. It is unlikely that observational effects can be entirely responsible for the trends, which suggest that major long-term changes may be occurring at E region heights.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Baggaley, W J -- New York, N.Y. -- Science. 1984 Aug 24;225(4664):830-3.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/17801151" target="_blank"〉PubMed〈/a〉
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    Secondary Education in Japan: Japan's High Schools (1984)
    American Association for the Advancement of Science (AAAS)
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    Publication Date: 1984-05-18
    Description: 〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Bartholomew, J R -- New York, N.Y. -- Science. 1984 May 18;224(4650):714-5.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/17780595" target="_blank"〉PubMed〈/a〉
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  • 180
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    The cultures of science and technology (1984)
    American Association for the Advancement of Science (AAAS)
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    Publication Date: 1984-04-06
    Description: 〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Baruch, J J -- New York, N.Y. -- Science. 1984 Apr 6;224(4644):7.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/17783497" target="_blank"〉PubMed〈/a〉
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  • 181
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    Ancient bisexual flowers (1984)
    American Association for the Advancement of Science (AAAS)
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    Publication Date: 1984-05-04
    Description: Fossil flowers discovered in 94-million-year-old clays of the Dakota Formation in Nebraska are among the earliest known demonstrably bisexual flowers. The flowers are of medium size and have pentamerous whorls of clearly differentiated floral parts, petals alternate with the sepals, short stamens are borne opposite the petals, the carpels are fused, and a receptacular disk is present. The pollen is small and tricolporate. These flowers appear to be well adapted to insect pollination. The numerous floral features and pollen characters provide sufficient diagnostic data to assess its systematic position. No extant order accommodates the features of this flower and it shares some features of various extant orders. The classification of flowering plants and our understanding of their evolution must be influenced by the fossilized remains of ancient flowers.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Basinger, J F -- Dilcher, D L -- New York, N.Y. -- Science. 1984 May 4;224(4648):511-3.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/17753776" target="_blank"〉PubMed〈/a〉
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    The European landscape: geomorphology of europe (1984)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1984-07-13
    Description: 〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Baker, V R -- New York, N.Y. -- Science. 1984 Jul 13;225(4658):161-2.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/17837922" target="_blank"〉PubMed〈/a〉
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  • 183
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    An argument for moderation: the culture of technology (1984)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1984-09-07
    Description: 〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Baum, R J -- New York, N.Y. -- Science. 1984 Sep 7;225(4666):1015.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/17783041" target="_blank"〉PubMed〈/a〉
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  • 184
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    Kin recognition (1984)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1984-05-04
    Description: 〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Bateson, P -- New York, N.Y. -- Science. 1984 May 4;224(4648):446.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/17753750" target="_blank"〉PubMed〈/a〉
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  • 185
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    The mohole project (1984)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1984-10-12
    Description: 〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Bascom, W -- New York, N.Y. -- Science. 1984 Oct 12;226(4671):114.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/17814317" target="_blank"〉PubMed〈/a〉
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  • 186
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    Successors to newton: optics after newton (1984)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1984-06-01
    Description: 〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Becher, H W -- New York, N.Y. -- Science. 1984 Jun 1;224(4652):982-3.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/17731993" target="_blank"〉PubMed〈/a〉
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  • 187
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    Space plasma physics: isotopic stack: measurement of heavy cosmic rays (1984)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1984-07-13
    Description: A stack of plastic nuclear track detectors was exposed to heavy cosmic rays on the pallet of Spacelab 1. Some layers of the stack were rotated with respect to the main stack to determine the arrival time of the particles. After return of the stack the latent particle tracks are revealed by chemical etching. Under the optical microscope the charge, mass, energy, and impact direction of the particles can be deduced from the track geometry.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Beaujean, R -- Schmidt, M -- Enge, W -- Siegmon, G -- Krause, J -- Fischer, E -- New York, N.Y. -- Science. 1984 Jul 13;225(4658):193-5.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/17837938" target="_blank"〉PubMed〈/a〉
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  • 188
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    Mississippi deltaic wetland survival: sedimentation versus coastal submergence (1984)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1984-06-08
    Description: Seasonal sedimentation, measured with the aid of artificial marker horizons, was markedly different in deteriorating as compared with stable marshes in the Mississippi River deltaic plain. Deteriorating marshes receive most sediment during storm events, whereas stable marshes receive substantial amounts of sediments during the spring river flood. The deteriorating marshes are accreting at a faster rate (1.5 centimeters per year at streamside, 0.9 centimeter per year at inland areas) than the stable marshes (1.3 centimeters per year at streamside, 0.6 centimeter per year at inland areas). However, relative to local apparent sea-level rise as measured by tide gauges in each area, the deteriorating marshes are not maintaining their intertidal elevation as well as the stable marshes. These results indicate the importance of considering accretion relative to submergence.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Baumann, R H -- Day, J W Jr -- Miller, C A -- New York, N.Y. -- Science. 1984 Jun 8;224(4653):1093-5.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/17735245" target="_blank"〉PubMed〈/a〉
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  • 189
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    Space plasma physics: phenomena induced by charged particle beams (1984)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1984-07-13
    Description: The effects of electron beam emissions from Spacelab were recorded with onboard diagnostic instruments. The variation of the Spacelab-shuttle potential with respect to the ambient plasma near the scientific air lock was investigated. Data on the waves and instabilities triggered by the electron beams are discussed. Within the electron gyrofrequency and electron plasma frequency range, strong signals were detected by both electric and magnetic antennas during the beam emissions. The frequencies of the emitted waves were compared to the characteristic plasma frequencies to enable mode identification.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Beghin, C -- Lebreton, J P -- Maehlum, B N -- Troim, J -- Ingsoy, P -- Mimacrchau, J L -- New York, N.Y. -- Science. 1984 Jul 13;225(4658):188-91.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/17837936" target="_blank"〉PubMed〈/a〉
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  • 190
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    Designs and ideals: campus (1984)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1984-05-18
    Description: 〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Bender, T -- New York, N.Y. -- Science. 1984 May 18;224(4650):715-7.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/17780596" target="_blank"〉PubMed〈/a〉
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  • 191
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    Dissolution of kroc foundation (1984)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1984-01-20
    Description: 〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Benes, E E -- New York, N.Y. -- Science. 1984 Jan 20;223(4633):238.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/17801575" target="_blank"〉PubMed〈/a〉
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  • 192
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    Event-related brain potentials in boys at risk for alcoholism (1984)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1984-09-28
    Description: Recent neurophysiological findings have demonstrated that abstinent chronic alcoholics manifest deficits in event-related brain potentials. To explore possible biological antecedents of alcoholism the present study examined boys at high risk for alcoholism. Event-related brain potentials were recorded from biological sons of alcoholic fathers and matched control boys. Differences in the P3 component of the potentials were obtained between the high-risk and control subjects.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Begleiter, H -- Porjesz, B -- Bihari, B -- Kissin, B -- AA 05524/AA/NIAAA NIH HHS/ -- New York, N.Y. -- Science. 1984 Sep 28;225(4669):1493-6.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/6474187" target="_blank"〉PubMed〈/a〉
    Keywords: Adolescent ; Adult ; Alcoholism/*genetics/physiopathology ; Analysis of Variance ; Brain/*physiopathology ; Child ; Evoked Potentials ; Fathers ; Humans ; Male ; Memory Disorders/etiology ; Risk
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  • 193
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    Allometry: scaling (1984)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1984-12-21
    Description: 〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Bennett, A F -- New York, N.Y. -- Science. 1984 Dec 21;226(4681):1412-3.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/17788992" target="_blank"〉PubMed〈/a〉
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  • 194
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    Functional expression of a cloned I-A beta k gene in B-lymphoma cells (1984)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1984-02-24
    Description: The immune response genes of the mouse encode two cell-surface glycoproteins, I-A and I-E, that play critical roles in determining the animal's immune responsiveness. The I-A antigen contains two chains, alpha and beta. A cloned beta-chain gene, I-A beta k, was introduced into B-lymphoma cells that express I-Ad. The transfected gene was successfully expressed on the cell surface of the recipient cells and was functional in stimulating allospecific T cells.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Ben-Nun, A -- Glimcher, L H -- Weis, J -- Seidman, J G -- AI18436/AI/NIAID NIH HHS/ -- New York, N.Y. -- Science. 1984 Feb 24;223(4638):825-8.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/6420890" target="_blank"〉PubMed〈/a〉
    Keywords: Animals ; B-Lymphocytes/*physiology ; Cloning, Molecular ; Gene Expression Regulation ; *Genes, MHC Class II ; Heterozygote ; Lymphocyte Cooperation ; Lymphoma ; Macromolecular Substances ; Mice ; T-Lymphocytes/physiology ; Transfection ; Transformation, Genetic
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  • 195
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    Paleoceanographic events and deep-sea ostracodes (1984)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1984-06-22
    Description: Eight recognized or theorized paleoceanographic events during the past 70 million years were tested against changes in the global deep-sea benthic ostracode fauna. Two events, the sudden Cretaceous-Tertiary boundary event at 66 million years ago and the more gradual 40-million-year event (formation of the psychrosphere), show up most dramatically. Before the 40-million-year event, ostracodes freely radiated into the deeper water regions but were provincial. The development of thermal stratification isolated these deep-water taxa, mostly the survivors of the Cretaceous-Tertiary boundary event, which adapted to a new, free-flowing but more frigid ecosystem and spread rapidly throughout the world.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Benson, R H -- Chapman, R E -- Deck, L T -- New York, N.Y. -- Science. 1984 Jun 22;224(4655):1334-6.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/17837191" target="_blank"〉PubMed〈/a〉
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  • 196
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    Patents and research freedom (1984)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1984-07-27
    Description: 〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Berkowitz, K P -- New York, N.Y. -- Science. 1984 Jul 27;225(4660):366.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/17813237" target="_blank"〉PubMed〈/a〉
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  • 197
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    Invertebrate vision: photoreception and vision in invertebrates (1984)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1984-08-24
    Description: 〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Bernard, G D -- New York, N.Y. -- Science. 1984 Aug 24;225(4664):827-8.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/17801148" target="_blank"〉PubMed〈/a〉
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  • 198
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    Induction of pituitary lactotrope differentiation by luteinizing hormone alpha subunit (1984)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1984-11-02
    Description: Addition of gonadotropin releasing hormone to cultures of fetal rat pituitary induced differentiation of lactotropes as revealed by immunocytochemistry. Antiserum to luteinizing hormone (LH) (recognizing native LH), but not antiserum to LH-beta (recognizing both native LH and its beta subunit), inhibited this induction. Further addition of highly purified LH-alpha subunit in culture medium also induced lactotrope differentiation. Thus, the alpha subunit may have a specific biological activity of its own with probable practical use in clinical investigations.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Begeot, M -- Hemming, F J -- Dubois, P M -- Combarnous, Y -- Dubois, M P -- Aubert, M L -- New York, N.Y. -- Science. 1984 Nov 2;226(4674):566-8.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/6208610" target="_blank"〉PubMed〈/a〉
    Keywords: Animals ; Fetus/physiology ; Glycoprotein Hormones, alpha Subunit ; Humans ; Luteinizing Hormone/immunology/pharmacology/physiology ; Peptide Fragments/*pharmacology/physiology ; Pituitary Gland/*drug effects/growth & development ; Pituitary Hormone-Releasing Hormones/pharmacology ; Pituitary Hormones, Anterior/*pharmacology/physiology ; Rats
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  • 199
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    The imprint of upwelling: coastal upwelling (1984)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1984-03-23
    Description: 〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Berger, W H -- New York, N.Y. -- Science. 1984 Mar 23;223(4642):1283-4.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/17759361" target="_blank"〉PubMed〈/a〉
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  • 200
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    Extrapulmonary gas exchange enhances brain oxygen in pigeons (1984)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1984-11-02
    Description: Blood in mouth, nose, and eye tissues of birds cools by evaporation, then flows to a cephalic vascular heat exchanger, the ophthalmic rete. There, acting as a heat sink, blood from the evaporative surfaces cools arterial blood flowing counter-current to it toward the brain. The brain thus remains cooler than the body core. Data for unanesthetized domestic pigeons (Columba livia) suggest that in addition to losing heat, blood perfusing the evaporative surfaces also exchanges oxygen and carbon dioxide with air. In the heat exchanger, this blood apparently gives up oxygen to, and gains carbon dioxide from, arterial blood. The consequent increase in oxygen and decrease in carbon dioxide in the brain's arterial blood enhance diffusion of these gases in, and oxygen supply to, the brain. Such events may help birds maintain the brain's oxygen supply during the high systemic demand of exercise and at the reduced oxygen availability of high altitude.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Bernstein, M H -- Duran, H L -- Pinshow, B -- RR08136/RR/NCRR NIH HHS/ -- New York, N.Y. -- Science. 1984 Nov 2;226(4674):564-6.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/6436975" target="_blank"〉PubMed〈/a〉
    Keywords: Animals ; Body Temperature Regulation ; Brain/metabolism ; *Brain Chemistry ; Carbon Dioxide/analysis/cerebrospinal fluid ; Cerebrovascular Circulation ; Columbidae ; Hydrogen-Ion Concentration ; Oxygen/*analysis/cerebrospinal fluid ; Partial Pressure
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