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  • 1
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    Role of ANC-1 in tethering nuclei to the actin cytoskeleton (2002)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 2002-08-10
    Description: Mutations in anc-1 (nuclear anchorage defective) disrupt the positioning of nuclei and mitochondria in Caenorhabditis elegans. ANC-1 is shown to consist of mostly coiled regions with a nuclear envelope localization domain (called the KASH domain) and an actin-binding domain; this structure was conserved with the Drosophila protein Msp-300 and the mammalian Syne proteins. Antibodies against ANC-1 localized cytoplasmically and were enriched at the nuclear periphery in an UNC-84-dependent manner. Overexpression of the KASH domain or the actin-binding domain caused a dominant negative anchorage defect. Thus, ANC-1 may connect nuclei to the cytoskeleton by interacting with UNC-84 at the nuclear envelope and with actin in the cytoplasm.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Starr, Daniel A -- Han, Min -- F32 GM020127/GM/NIGMS NIH HHS/ -- New York, N.Y. -- Science. 2002 Oct 11;298(5592):406-9. Epub 2002 Aug 8.〈br /〉〈span class="detail_caption"〉Author address: 〈/span〉Howard Hughes Medical Institute and Department of Molecular, Cellular and Developmental Biology, University of Colorado, Boulder, CO 80309, USA.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/12169658" target="_blank"〉PubMed〈/a〉
    Keywords: Actins/*metabolism ; Alleles ; Animals ; Animals, Genetically Modified ; Caenorhabditis elegans/genetics/*metabolism/ultrastructure ; Caenorhabditis elegans Proteins/analysis/chemistry/genetics/*metabolism ; Cell Nucleus/*metabolism ; Cytoplasm/chemistry ; Cytoskeleton/*metabolism ; Genes, Helminth ; Membrane Glycoproteins/metabolism ; Microfilament Proteins/analysis/chemistry/genetics/*metabolism ; Mitochondria/ultrastructure ; Mutation ; Nuclear Envelope/chemistry/genetics/metabolism ; Nuclear Proteins/metabolism ; Phenotype ; Protein Binding ; Protein Structure, Tertiary ; Recombinant Fusion Proteins/metabolism
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
    Published by American Association for the Advancement of Science (AAAS)
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  • 2
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    The E3 Ubiquitin Ligase MIB-1 Is Necessary To Form the Nuclear Halo in Caenorhabditis elegans Sperm (2018)
    Genetics Society of America (GSA)
    Details
    Publication Date: 2018-07-03
    Description: Unlike the classical nuclear envelope with two membranes found in other eukaryotic cells, most nematode sperm nuclei are not encapsulated by membranes. Instead, they are surrounded by a nuclear halo of unknown composition. How the halo is formed and regulated is unknown. We used forward genetics to identify molecular lesions behind three classical fer (fertilization defective) mutations that disrupt the ultrastructure of the Caenorhabditis elegans sperm nuclear halo. We found fer-2 and fer-4 alleles to be nonsense mutations in mib-1 . fer-3 was caused by a nonsense mutation in eri-3 . GFP::MIB-1 was expressed in the germline during early spermatogenesis, but not in mature sperm. mib-1 encodes a conserved E3 ubiquitin ligase homologous to vertebrate Mib1 and Mib2, which function in Notch signaling. Here, we show that mib-1 is important for male sterility and is involved in the regulation or formation of the nuclear halo during nematode spermatogenesis.
    Electronic ISSN: 2160-1836
    Topics: Biology
    Published by Genetics Society of America (GSA)
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  • 3
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    Cell biology. Nuclei get TAN lines (2010)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 2010-08-21
    Description: 〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Starr, Daniel A -- New York, N.Y. -- Science. 2010 Aug 20;329(5994):909-10. doi: 10.1126/science.1194562.〈br /〉〈span class="detail_caption"〉Author address: 〈/span〉Department of Molecular and Cellular Biology, College of Biological Sciences, University of California, Davis, CA 95616, USA. dastarr@ucdavis.edu〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/20724623" target="_blank"〉PubMed〈/a〉
    Keywords: Actins/*physiology ; Animals ; Cell Movement ; Cell Nucleus/*physiology ; Cytoskeleton/physiology ; Fibroblasts ; Movement
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
    Published by American Association for the Advancement of Science (AAAS)
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  • 4
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    Endogenous late positive component of the evoked potential in cats corresponding to P300 in humans (1981)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1981-02-06
    Description: A long-latency component of the averaged evoked potential recorded from cats was present only when the evoking stimulus was relevant to the task. The amplitude of this component varied inversely with stimulus probability and was independent of stimulus modality.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Wilder, M B -- Farley, G R -- Starr, A -- NS 11876-06/NS/NINDS NIH HHS/ -- New York, N.Y. -- Science. 1981 Feb 6;211(4482):605-7.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/7455702" target="_blank"〉PubMed〈/a〉
    Keywords: Animals ; Avoidance Learning/physiology ; Brain/*physiology ; Cats ; Conditioning, Classical ; *Evoked Potentials ; Habituation, Psychophysiologic ; *Perception/physiology
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
    Published by American Association for the Advancement of Science (AAAS)
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  • 5
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    Task-relevant late positive component of the auditory event-related potential in monkeys resembles P300 in humans (1984)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1984-01-13
    Description: A long-latency (300-millisecond), vertex-positive component of the event-related potential recorded from monkeys was present only when the eliciting stimulus was relevant to the task. The amplitude of this component varied inversely with stimulus probability and was dissociable from motor responses.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Arthur, D L -- Starr, A -- MH14599-06/MH/NIMH NIH HHS/ -- NS11876-08/NS/NINDS NIH HHS/ -- New York, N.Y. -- Science. 1984 Jan 13;223(4632):186-8.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/6691145" target="_blank"〉PubMed〈/a〉
    Keywords: Acoustic Stimulation ; Animals ; Electroencephalography ; Electrooculography ; *Evoked Potentials, Auditory ; Humans ; Macaca nemestrina ; Probability
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
    Published by American Association for the Advancement of Science (AAAS)
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  • 6
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    Acute effects of alcohol on auditory brainstem potentials in humans (1978)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1978-07-14
    Description: Auditory brainstem potentials were recorded from human subjects before and after an intoxicating dose of alcohol. Following alcohol ingestion there were significant, progressive increases in the latencies of brainstem potential peaks III through VII. No changes in peak amplitudes were found. The results indicate that alcohol has a depressive effect on neural transmission within the primary auditory brainstem pathway.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Squires, K C -- Chu, N S -- Starr, A -- New York, N.Y. -- Science. 1978 Jul 14;201(4351):174-6.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/208148" target="_blank"〉PubMed〈/a〉
    Keywords: Adult ; Alcoholic Intoxication/*physiopathology ; Auditory Pathways/*drug effects ; Auditory Perception/drug effects ; Brain Stem/*drug effects/physiology ; Ethanol/*pharmacology ; Evoked Potentials/drug effects ; Humans ; Male ; Synaptic Transmission/drug effects
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
    Published by American Association for the Advancement of Science (AAAS)
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  • 7
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    Size Differentiation Of A Continuous Stream Of Particles Using Acoustic Emissions (2016)
    Institute of Physics (IOP)
    Details
    Publication Date: 2016-12-02
    Description: Procter and Gamble (P&G) require an online system that can monitor the particle size distribution of their washing powder mixing process. This would enable the process to take a closed loop form which would enable process optimisation to take place in real time. Acoustic Emission (AE) was selected as the sensing method due to its non-invasive nature and primary sensitivity to frequencies which particle events emanate. This work details the results of the first experiment carried out in this research project. This experiment involved the use of AE to distinguish between the sizes of sieved polyethylene particle (53-250microns) and glass beads (150-600microns) which were dispensed on a target plate using a funnel. By conducting a threshold analysis of the impact peaks in the signal, the sizes of the particles could be distinguished and a signal feature was found which could be directly linked to the sizes of the particles.
    Print ISSN: 1757-8981
    Electronic ISSN: 1757-899X
    Topics: Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics
    Published by Institute of Physics (IOP)
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  • 8
    Electronic Resource
    Electronic Resource
    Giant magnetoresistance in heterogeneous Cu–Co and Ag–Co alloy films (invited) : 37th Annual conference on magnetism and magnetic materials (1993)
    [S.l.] : American Institute of Physics (AIP)
    Journal of Applied Physics 73 (1993), S. 5320-5325 
    Details
    ISSN: 1089-7550
    Source: AIP Digital Archive
    Topics: Physics
    Notes: Giant magnetoresistance in sputtered single films of Cu–Co and Ag–Co heterogeneous alloys is discussed. The films consist of Co-rich precipitates in a nonferromagnetic matrix. The Ag–Co films have higher Δρ/ρ and Δρ values than the Cu–Co films, possibly due to less Co dissolved in the Ag matrix. Δρ scales inversely with precipitate particle size, implying that Co-rich clusters ≤20 A(ring) diameter may be most effective for spin dependent scattering. This trend of the data and a phenomenological model suggest that interfacial spin dependent scattering is significantly stronger than the scattering within the Co-rich particles.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1063/1.353767
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  • 9
    Electronic Resource
    Electronic Resource
    Apparatus for in situ measurement of surface magnetic moments prepared in UHV (1991)
    [S.l.] : American Institute of Physics (AIP)
    Review of Scientific Instruments 62 (1991), S. 484-488 
    Details
    ISSN: 1089-7623
    Source: AIP Digital Archive
    Topics: Physics , Electrical Engineering, Measurement and Control Technology
    Notes: An apparatus for making in situ measurements of the magnetic moment of submonolayer through multimonolayer samples deposited in a UHV chamber is described. The UHV chamber is designed to be used with a commercial SQUID magnetometer with a sensitivity of ∼10−8 emu. The component of magnetic moment parallel to the sample surface may be measured over the temperature range 4–400 K and for magnetic fields (applied parallel to the surface) up to 5 T. A thin re-entrant metal tape is used both as an initial substrate for the deposition of any desired films, and as the means of transporting the deposited sample from the evaporation and evaluation regions of the vacuum chamber to the SQUID analysis region. Some results for Fe evaporated on polycrystalline Ag films are presented.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1063/1.1142092
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  • 10
    Electronic Resource
    Electronic Resource
    Direct dc magnetization measurements of Fe on Ag (abstract) (1987)
    [S.l.] : American Institute of Physics (AIP)
    Journal of Applied Physics 61 (1987), S. 3366-3366 
    Details
    ISSN: 1089-7550
    Source: AIP Digital Archive
    Topics: Physics
    Notes: We have made measurements of the temperature and field dependence of the dc magnetization of Fe atoms deposited on polycrystalline Ag substrates in the range 0.1–100 monolayers equivalent mass coverage. Our experimental technique is to couple an ultrahigh vacuum sample preparation and transport chamber to a SQUID dc magnetometer. We shall present an analysis of these data and a comparison of the deduced saturation moment and anisotropy constant with the theoretical and experimental results of the companion papers in this symposium.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1063/1.338772
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