Publication Date:
1984-12-07
Description:
The origins of several of the differentiated cell lineages of the advanced sea urchin embryo are well defined. Cytological application of molecular probes to three lineages, those responsible for the formation of the skeleton, the gut, and the aboral ectodermal wall of the late embryo, has demonstrated expression of lineage-specific genes long before overt morphological differentiation. These observations lead to useful generalizations regarding the processes of gene regulation that underlie the molecular biology of cell lineage specification in the embryo.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Angerer, R C -- Davidson, E H -- GM-25553/GM/NIGMS NIH HHS/ -- HD-05753/HD/NICHD NIH HHS/ -- New York, N.Y. -- Science. 1984 Dec 7;226(4679):1153-60.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/6594757" target="_blank"〉PubMed〈/a〉
Keywords:
Actins/genetics
;
Animals
;
Blastomeres/physiology
;
Calcium-Binding Proteins/genetics
;
*Cell Differentiation
;
Cytoplasm/physiology
;
Ectoderm/physiology
;
*Gene Expression Regulation
;
Genetic Markers
;
Germ Layers/physiology
;
Intestines/embryology
;
Morphogenesis
;
RNA, Messenger/metabolism
;
Sea Urchins/*embryology
Print ISSN:
0036-8075
Electronic ISSN:
1095-9203
Topics:
Biology
,
Chemistry and Pharmacology
,
Computer Science
,
Medicine
,
Natural Sciences in General
,
Physics
