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  • 1
    Electronic Resource
    Electronic Resource
    Springer
    Environmental management 4 (1980), S. 111-124 
    ISSN: 1432-1009
    Keywords: Carolinian ; Ecology ; Ideology ; Policy ; Rondeau ; Technology ; Wildland Management ; Parks
    Source: Springer Online Journal Archives 1860-2000
    Topics: Energy, Environment Protection, Nuclear Power Engineering
    Notes: Abstract This is a critical examination of some of the basic concepts that have guided management of parks and related reserves, often termed wildlands. Study is focussed on Rondeau Provincial Park, Ontario, and on concepts such as wilderness, primeval forest, and the Carolinian forest. Deer culling and other management policies and practices have been based upon the idea that the highly valued sassafras, tulip, and other species of the Carolinian forest are decreasing due to browsing. Field mapping and analysis of historic vegetation records indicate that this trend is not in fact occurring. Historic research also reveals difficulties in defining the Carolinian or other perceived types of forest for management purposes. A major reassessment of ideology and management policy and practice seem to be required in Rondeau and other wildlands. Vague or general concepts such as wilderness or preservation should be strongly complemented and supported by more precise statements of objectives, a learning attitude, and experimentation and research. As a result of the technical uncertainties and value judgments frequently involved, management should also be based upon the expressed preferences and continuing involvement of citizens.
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  • 2
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    Environmental management 8 (1984), S. 309-324 
    ISSN: 1432-1009
    Keywords: Animals ; Indicators ; Air pollution ; Ecosystem responses
    Source: Springer Online Journal Archives 1860-2000
    Topics: Energy, Environment Protection, Nuclear Power Engineering
    Notes: Abstract With existing and proposed air-quality regulations, ecological disasters resulting from air emissions such as those observed at Copperhill, Tennessee, and Sudbury, Ontario, are unlikely. Current air-quality standards, however, may not protect ecosystems from subacute and chronic exposure to air emissions. The encouragement of the use of coal for energy production and the development of the fossil-fuel industries, including oil shales, tar sands, and coal liquification, point to an increase and spread of fossil-fuel emissions and the potential to influence a number of natural ecosystems. This paper reviews the reported responses of ecosystems to air-borne pollutants and discusses the use of animals as indicators of ecosystem responses to these pollutants. Animal species and populations can act as important indicators of biotic and abiotic responses of aquatic and terrestrial ecosystems. These responses can indicate long-term trends in ecosystem health and productivity, chemical cycling, genetics, and regulation. For short-term trends, fish and wildlife also serve as monitors of changes in community structure, signaling food-web contamination, as well as providing a measure of ecosystem vitality. Information is presented to show not only the importance of animals as indicators of ecosystem responses to air-quality degradation, but also their value as air-pollution indices, that is, as air-quality-related values (AQRV), required in current air-pollution regulation.
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  • 3
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    Environmental management 5 (1981), S. 495-505 
    ISSN: 1432-1009
    Keywords: Suitability analysis ; Land-use assessment ; Ecology ; Planning ; Human ecology
    Source: Springer Online Journal Archives 1860-2000
    Topics: Energy, Environment Protection, Nuclear Power Engineering
    Notes: Abstract Beginning with the passage of the National Environmental Policy Act in 1969, the federal government of the United States has enacted numerous pieces of legislation intended to protect or conserve the environment. Other national governments have also enacted environmental legislation during the past two decades. State and local governments have also adopted policies concerned with environmental planning and management. Multiple laws and overlapping governmental agency responsibilities have confused development and resource management efforts. A comprehensive methodology that integrates the legal mandates and the agency missions into a common and unified framework is needed. Ecological planning offers such a method. Application of the method allows planners and resource managers to better understand the nature and character of the land and/or resource and therefore make better decisions about its appropriate use or management. The steps taken in an ecological planning process—1) goal setting, 2) inventory and analysis of data, 3) suitability analysis, 4) developing alternatives, 5) implementation, 6) administration, and 7) evaluation—are outlined and explained. Hand-drawn overlays and computer programs as techniques for handling ecological planning information are compared. Observations and suggestions for further research are offered.
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  • 4
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    Archives of microbiology 131 (1982), S. 107-111 
    ISSN: 1432-072X
    Keywords: Cyanophyta ; Cyanobacteria ; Oscillatoria rubescens ; Photosynthetic pathways ; Photosynthetic enzymes ; Ecology
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology
    Notes: Abstract Short term14C labelling experiments and enzymatic activities related to primary pathways of photosynthesis have been studied in the cyanophytaOscillatoria rubescens D.C. from axenic cyclostat cultures. Responses of samples from cultures with different amounts of nitrogen are presented and compared. Variations in photosynthetic pigments are used to quantify the degree of nitrogen starvation at different levels. PEPcarboxylase activity remains low and is not affected by nitrogen starvation. RuBPcarboxylase activity is lowered to nearly two thirds of its normal metabolic rate by starvation but PEPcarboxykinase and aspartate aminotransferase activities are significantly higher in this case. Malate dehydrogenase is slightly altered and malic enzyme is never active. Starved algae replaced in fresh complete media fix rapidly14C in nitrogen compounds such as amino acids. Results are discussed in regard to both physiological and ecological characteristics ofO. rubescens. PEPcarboxykinase can play a role in making efficient use of HCO 3 - .
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  • 5
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    Archives of microbiology 139 (1984), S. 351-354 
    ISSN: 1432-072X
    Keywords: Aerobic denitrification ; Thiosphaera pantotropha ; Nitrate reduction ; Bacterial selection ; Ecology ; Oxygen
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology
    Notes: Abstract During studies on the denitrifying mixotroph, Thiosphaera pantotropha, it has been found that this organism is capable of simultaneously utilizing nitrate and oxygen as terminal electron acceptors in respiration. This phenomenon, termed aerobic denitrification, has been found in cultures maintained at dissolved oxygen concentrations up to 90% of air saturation. The evidence for aerobic denitrification was obtained from a number of independant experiments. Denitrifying enzymes were present even in organisms growing aerobically without nitrate. Aerobic yields on acetate were higher (8.1 g protein/mol) without than with (6.0 g protein/mol) nitrate, while the anaerobic yield with nitrate was even lower (4 g protein/mol). The maximum specific growth rate of Tsa. pantotropha was higher (0.34 h-1) in the presence of both oxygen (〉80% air saturation) and nitrate than in similar cultures not supplied with nitrate (0.27 h-1), indicating that the rate of electron transport to oxygen was limiting. This was confirmed by oxygen uptake experiments which showed that although the rate of respiration on acetate was not affected by nitrate, the total oxygen uptake was reduced in its presence. The original oxygen uptake could be restored by the addition of denitrification inhibitors.
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  • 6
    ISSN: 1432-072X
    Keywords: Bacillus tusciae ; New species ; Taxonomy ; Ecology ; Chemolithoautotrophy ; Hydrogen oxidation ; Hydrogenase ; Thermophily ; Geothermal manifestation ; Solfatara
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology
    Notes: Abstract A thermophilic, chemolithoautotrophic, hydrogen-oxidizing sporeformer has been isolated from ponds in a solfatara in the geothermal area of Tuscany (Italy). Some physicochemical parameters of the habitat were determined. The habitat was characterized by the presence of molecular hydrogen in the escaping gases, a very low content of phosphate and organic matter. Temperature and water level in the ponds varied widely. The organism formed oval, subterminal spores, which swelled distinctly the sporangium. Optimal growth occured between pH 4.2 and 4.8 at 55°C. It grew best under autotrophic conditions, but organic substrates including short chain fatty acids, amino acids and alcohols could also support heterotrophic growth. Sugars were not metabolized. The hydrogenase was soluble but did not reduce pyridine nucleotides. Based on its morphological and biochemical features, the organism belongs to the genus Bacillus, but differs from all the previously described species. It is therefore proposed as constituting a new species, Bacillus tusciae.
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  • 7
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    Journal of mathematical biology 12 (1981), S. 343-354 
    ISSN: 1432-1416
    Keywords: Ecology ; Periodic differential equations ; Optimization
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Mathematics
    Notes: Summary The theory developed here applies to populations whose size x obeys a differential equation, $$\dot x = r(t)xF(x,t)$$ in which r and F are both periodic in t with period p. It is assumed that the function r, which measures a population's intrinsic rate of growth or intrinsic rate of adjustment to environmental change, is measurable and bounded with a positive lower bound. It is further assumed that the function F, which is determined by the density-dependent environmental influences on growth, is such that there is a closed interval J, with a positive lower bound, in which there lies, for each t, a number K(t) for which $$F(K(t),t) = 0$$ and, as functions on J × ℝ, F is continuous, while ∂F/∂x is continuous, negative, and bounded. Because x(t) = 0, 〉 0, or 〈 0 in accord with whether K(t) = x(t), K(t) 〉 x(t), or K(t) 〈 x(t), the number K(t) is called the “carrying capacity of the environment at time t”. The assumptions about F imply that the number K(t) is unique for each t, depends continuously and periodically on t with period P, and hence attains its extrema, K min and K max. It is, moreover, easily shown that the differential equation for x has precisely one solution x * which has its values in J and is bounded for all t in ℝ; this solution is of period p, is asymptotically stable with all of J in its domain of attraction, and is such that its minimum and maximum values, x min * and x max * , obey $$K_{min} \leqslant x_{min}^* \leqslant x_{max}^* \leqslant K_{max}^* .$$ The following question is discussed: If the function F is given, and the function r can be chosen, which choices of r come close to maximizing, x min * ? The results obtained yield a procedure for constructing, for each F and each ɛ 〉 0, a function r such that x min * 〉 K max − ɛ.
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  • 8
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    Journal of mathematical biology 18 (1983), S. 255-280 
    ISSN: 1432-1416
    Keywords: Population dyamics ; Ecology ; Periodic solutions
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Mathematics
    Notes: Abstract A model of the competition of n species for a single essential periodically fluctuating nutrient is considered. Instead of the familiar Michaelis-Menten kinetics for nutrient uptake, we assume only that the uptake rate functions are positive, increasing and bounded above. Sufficient conditions for extinction are given. The existence of a nutrient threshold under which the Principle of Competitive Exclusion holds, is proven. For two species systems the following very general result is proven: All solutions of a τ-periodic, dissipative, competitive system are either τ-periodic or approach a τ-periodic solution. A complete description of the geometry of the Poincaré operator of the two species system is given.
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  • 9
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    Plant ecology 44 (1981), S. 13-24 
    ISSN: 1573-5052
    Keywords: Aceri-Fagetum ; Alpine timberline ; Dynamics of stands ; Ecology ; Fagus silvatica ; Morphogenesis ; Polycormons ; Vegetative regeneration
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology
    Notes: Summary In the Central Europaean mountain ranges, the alpine timberline is usually formed by Picea abies or by other conifers (Larix decidua, Pinus mugo, Pinus cembra). Unlike in the East Europaean mountains, the Balkan Peninsula, the Europaean Mediterranean and Les Vosges, Fagus silvatica occurs sporadically on the alpine timberline in this area where it forms very specific woods. This type of the alpine timberline is bound to the association Aceri-Fagetum (Bartsch 1940, Moor 1952). This association is found on the highest sites of the Fagion alliance in the subalpine vegetation zone. Within this zone, the association is bound to localities with heavy snowfall and a submaritime climat. It occupies larger areas in the Swiss Jura and in Les Vosges. In other Central Europaean mountains (the Alps, Schwarzwald, Krkonoše etc.) it occus in isolated areas only. Many trunk deformations and bush forms are found with Fagus on a large scale in the snow impacted localities (steep slopes, periphery of corries, avalanche slopes etc.). Crawling and sliding snow causes these growth deformations in the Fagus seedlings since their first year. The general increase of the vegetative propagation is a remarkable and exceptional response of Fagus in adapting to these extreme growth conditions. Under alpine timberline conditions, the generative propagation is very limited. The vegetative shoots with adventitious root systems are formed mainly from branches layering in the humus. The typical monocormonal tree-form of Fagus from lower altitudes turns in this way into a polycormon. From an evolutionary point of view, it is a suitable substitution; but from the ecological viewpoint, however, it is a sturdy growth form. In its typical form, the polycormon is formed by a number of vegetative shoots, which may be deformed but are very elastic and resistent. The number of shoots in a polycormon varies from 3–5 below, and up to 40–50 at and above the timberline. They are formed by shoots of a number of filial successions. The decay of a polycormon results from decreasing vitality of single shoots or, very often, it is caused by the impact of snow and ice. Considering, however, the fact that single shoots have a sufficient adventitious root system and are thus physiologically independent, the dying of the other shoots does not mean a danger for the existence of the remaining part of the polycormon. The age of a polycormon as a whole is difficult to determine. Fagus polycormons can be considered as a typical growthform of the highest sites of the association Aceri-Fagetum. No other tree species is able to form close stands under these conditions. This phenomenon is of primary importance for the existence of this plant community. The unusual character of the structure and dynamics of the highest Aceri-Fagetum stands gives rise to a special type of the alpine timberline which should be understood not as a ‘line’ but as a transitional zone between the closed stands and the hon-wooded plant communities of the subalpine vegetation zone. The dynamic succession of the Fagus polycormons guarantees the stability of the Fagus stands forming the alpine timberline.
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  • 10
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    Plant ecology 48 (1982), S. 123-131 
    ISSN: 1573-5052
    Keywords: Ecology ; Fringe communities ; Numerical classification ; Ostrya carpinifolia woods ; Phytogeographic elements ; Phytosociology ; Southern Alps (N-Italy) ; Vegetation dynamics ; Wood edge communities
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology
    Notes: Abstract Forest regeneration in the vegetation complex of the submontane belt in the Southern Alps involves the active participation ofOstrya carpinifolia woods and their wood edge communities. The corresponding syndynamical processes are described by employing phytosociological, phytogeographical and ecological methods. It is concluded that: (i) The communities of the grassland-wood transition are of major importance in the successional developments in this man-made vegetation complex. (ii) Many species occurring in the region of the deciduous forests of Eurasia find their refuge in such transitional communities and are supposed to play an important part in the succession. (iii) Ostrya carpinifolia is considered as an early successional tree species.
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  • 11
    ISSN: 1573-5052
    Keywords: Alyssum serpyllifolium subspecies ; Nickel accumulation ; Nickel tolerance ; Ecology
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology
    Notes: Abstract Experiments were carried out on the tolerance to, and uptake of, nickel by three iberian subspecies of Alyssum serpylliforium Desf. Two of these subspecies, the serpentine-endemic ssp. lusitanicum from Bragança, Portugal and ssp. malacitanum from Málaga, Spain, are hyperaccumulators (〉 1000 μg/g in dried material) of nickel. Their possible ancestor, ssp. serpyllifolium (from Granada, Spain) was a non-accumulator of this element. Seeds of the two serpentine-endemics germinated extensively in nickel concentrations up to 12 000 μg/g (1.2%) whereas ssp. serpyllifolium only germinated in nickel concentrations below 60 μg/ml. Tolerance tests involving measurement of new root lengths of excised seedlings placed in varying nickel concentrations, again showed much greater tolerance of the two serpentinophytes. In both series of experiments, the order of tolerance was: ssp. lusitanicum 〉 ssp. malacitanum 〉 ssp. serpyllifolium. In pot trials involving seedlings of ssp. malacitanum grown in mixtures containing varying amounts of calcium, magnesium, and nickel, the most important finding was that plants will tolerate higher nickel contents in the soil when excess calcium is added. This is achieved by lowering the uptake of nickel. There appeared to be some concomitant reduction in calcium uptake in the presence of nickel, and some increase in uptake of magnesium. The resultant lower calcium/magnesium ratio in the plant, though not symptomatic of a favourable condition for colonization of serpentine soils, probably results from a mechanism which renders nickel innocuous to the plant at the expense of calcium uptake. It is suggested that the physiological characters of ssp. lusitanicum and ssp malacitanum are sufficiently different to support arguments for promoting the latter to full specific rank as has now been done for ssp. lusitanicum.
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  • 12
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    Plant ecology 55 (1984), S. 57-64 
    ISSN: 1573-5052
    Keywords: Ecology ; Hepaticae ; Pioneer vegetation ; Resurrection (poikilohydric) plants ; Riccia ; South West Africa
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology
    Notes: Abstract Three associations of the Nanocyperion teneriffae Lebrun 1947 (Sporoboletalia festivi Lebrun 1947) are described. They are physiognomically and ecologically similar to associations of the Mediterranean Isoeto-Nanojuncetea Br.-Bl. et Tx. 1943 and Helianthemetalia guttati Br.-Bl. 1940. They are rich in very specialized therophytes and resurrection plants.
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  • 13
    ISSN: 1573-5036
    Keywords: Actinorhizas ; Ecology ; Gamma irradiation ; Hippophaë rhamnoides ; Longidorus ; Nematode ; Nodulation ; Root nodules ; Soil sterilization ; Succession
    Source: Springer Online Journal Archives 1860-2000
    Topics: Agriculture, Forestry, Horticulture, Fishery, Domestic Science, Nutrition
    Notes: Summary To explain the decline of Hippophaë scrub in the vegetation succession in the dunes of The Netherlands, the growth and nodulation of Hippophaë plants grown in pots, using soil from an early stage (site AH) and a post-optimum stage (site HP), were investigated. In HP-soil nodulation, yield, and the nitrogen and phosphorus content of test plants were always lower and the number of necrotic nodules and the dry matter content were always higher than in AH-soil, even after inoculation with crushed nodules and the addition of a nutrient solution. Plants in HP-soil also had darker roots, less root hairs, a higher number of short lateral roots and a higher percentage of dead roots than those in AH-soil. These characteristics of adverse growth conditions disappeared upon ignition or gamma-irradiation of HP-soil. Possible explanations of these results are discussed. The degeneration of Hippophaë scrub cannot be ascribed to the age of the plants, the absence of sufficient infective endophyte particles or to abiotic factors such as unfavourable physical (particle size) or chemical soil conditions but is caused by biotic factors. No indications were obtained that plant-pathogenic fungi and bacteria are involved. HP-soil in contrast to AH-soil, however, contained large numbers of the nematodeLongidorus sp., a species known to cause root deformations. The conclusion was that this nematode is one of the biotic factors involved in the degeneration of the Hippophaë scrub. This degeneration is due to a restriction of the root system resulting in a low phosphate uptake, a low nodulation capacity and, as a consequence, a low nitrogen content. The results demonstrate that biotic soil factors are important in influencing succession in higher plant communities.
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  • 14
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    Plant and soil 69 (1982), S. 293-297 
    ISSN: 1573-5036
    Keywords: Ecology ; Frankia ; Nitrogen fixation ; Water potential
    Source: Springer Online Journal Archives 1860-2000
    Topics: Agriculture, Forestry, Horticulture, Fishery, Domestic Science, Nutrition
    Notes: Summary Growth responses of Frankia isolates to decreasing water potential were monitored in systems where potentials were controlled by KCl, NaCl and Polyethylene glycol. The highest potential tested was −2 bar (basal medium). The general pattern emerging was that isolates fromAlnus glutinosa, A. viridis andComptonia peregrina showed declining growth at potentials below −2 to −5 bar. AMyrica gale isolate showed declining growth with decreasing potential. All isolates were more sensitive to decreases in potential in a matric controlled than an osmotic controlled system. They all showed approximately 50 percent growth reduction at −5 to −8 bar, and meagre growth at −16 bar after 35 days. The Comptonia isolate was the most vigorous at low potentials. Nitrogen fixation ability was monitored for two isolates. Highest specific activities were observed between −3 and −5 bar for the Myrica isolate and between −5 and −7.5 bar for theA. glutinosa isolate.
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  • 15
    ISSN: 1573-5036
    Keywords: Actinorhizas ; (Actinomycetes) ; Ecology ; Hippophaë ; (Mystiflora: Elaeagnaceae) ; Longidorus ; (Nematoda: Longidoridae) ; Nodulation ; Soil ; sterization ; Vegetational succession ; Tylenchorhynchus (Nematoda: Tylenchrohynchidae)
    Source: Springer Online Journal Archives 1860-2000
    Topics: Agriculture, Forestry, Horticulture, Fishery, Domestic Science, Nutrition
    Notes: Summary Hippophaë rhamnoides seedlings were grown in sterilized and unsterilized soil from a decliningH. rhamnoides scrub, to which different numbers ofLongidorus sp. andTylenchorhynchus microphasmis were added. In sterilized and unsterilized soil, retardation of growth, content of dry matter in the shoots, and incidence of deformed short lateral roots of test plants were positively correlated with counts of both nematode species. Nitrogen content in the shoots, nodulation on the roots of test plants and increase increase in nematodes were negatively correlated with the initial number of both nematode species in sterilized soil. In unsterilized soil, an unknown biotic factor was present that reduces growth ofH. rhamnoides, nodulation and multiplication of the nematodes. This factor seems to interact with the nematodes in reducing growth ofH. rhamnoides.
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  • 16
    ISSN: 1573-5036
    Keywords: Catalase ; Ecology ; Fertilizers ; H2O2∶H2O2 oxidoreductase ; Rhizosphere effects ; Soil enzymes
    Source: Springer Online Journal Archives 1860-2000
    Topics: Agriculture, Forestry, Horticulture, Fishery, Domestic Science, Nutrition
    Notes: Summary Catalase activity of a loamy sand under a 3-year crop rotation in the southeastern U.S.A. was monitored. Corn (Zea mays L.), cotton (Gossypium hirsutum L.), and soybean [Glycine max (L.) Merr.] were the summer crops in the rotation. Winter wheat (Triticum aestivum L.) was planted after corn, and soybean was followed by a winter fallow period. Cotton was followed by a mixture of common vetch (Vicia sativa L.) and crimson clover (Trifolium incarnatum Gibelli & Belli) which was eventually plow-incorporated as a green manure. Highest mean catalase activities were recorded in soil under the wheat, soybean, and winter legume crops; lowest activities were found in soil bearing corn and cotton, and during the winter fallow period. The fertilization regime influenced soil catalase activity independently of the crop. Soil deficient in any of the major elements showed low enzyme activity. Highest activity was found in soil fertilized with P and K, and with N supplied by a winter legume crop. Addition of supplementary mineral nitrogen to this regime reduced catalase activity. Elimination of the winter legume crop from an otherwise complete fertilization regime resulted in a drastic reduction in enzyme activity. In soil receiving a complete fertilization regime there was a close correlation between soil catalase and xylanase activities. A similar correlation between these two enzymes was not found in soil receiving incomplete fertilization.
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  • 17
    ISSN: 1573-5036
    Keywords: Chitin ; Chitinase ; Chitinglycanohydrolase ; E. C. 3.2.1.14 ; Ecology ; Fertilizers ; Rhizosphere effects ; Soil enzymes
    Source: Springer Online Journal Archives 1860-2000
    Topics: Agriculture, Forestry, Horticulture, Fishery, Domestic Science, Nutrition
    Notes: Summary Chitinase activity was determined by incubating a mixture of toluene-treated soil with 1% (w/w) colloidal chitin suspension for 18 h at 37°C and then, after dilution, assaying the amount of N-acetyl-glucosamine released. Maximal chitinase activity was observed at 45°C and optimal pH for enzymatic reaction was 5.0–5.5. Soil chitinase activity decreased with increasing soil depth and was significantly affected by crop cover and fertilization regime. Chitin added to soil stimulated chitinase activity. Enzyme activity was correlated with the soil fungal population but not with numbers of actinomycetes or bacteria. A specialized mycoflora was associated with chitin decomposition.
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  • 18
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    Hydrobiologia 76 (1981), S. 87-96 
    ISSN: 1573-5117
    Keywords: Ecology ; production ; Gulf of Bothnia ; pelagial ; benthos
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology
    Notes: Abstract Production biology in the Bothnian Bay is discussed and compared to that of the southern parts of the Baltic. Severe ice-conditions, low water temperatures in spring and early summer and a pronounced water-colouring cause a delay of the spring development of phytoplankton and a low annual production in the Bothnian Bay. This delay makes possible a higher efficiency of the pelagic system as the zooplankton fauna can develop in harmony with the food resources. The downward transport of energy and matter to the bottom communities from an efficient pelagial should be small and temporally unpredictable, which is thought to be an adequate explanation of the observed very low benthic fauna biomasses in the Bothnian Bay.
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  • 19
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    Hydrobiologia 73 (1980), S. 181-193 
    ISSN: 1573-5117
    Keywords: Ecology ; feeding ; invertebrate behavior ; larval biology ; Rotifer ; sessile rotifer ; substrate-dependent survivorship ; substrate selection
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology
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  • 20
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    Environmental biology of fishes 5 (1980), S. 27-32 
    ISSN: 1573-5133
    Keywords: Salvelinus fontinalis ; Salmo salar (ouananiche) ; Ecology ; Salmonids ; Atlantic salmon
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology
    Notes: Synopsis The age structures of brook charr (Salvelinus fontinalis) and ouananiche (Salmo salar) stocks inhabiting a large rapid the river Méo, tributary to the Caniapiscau River were used to compare population stability and production of these species in north central Quebec. The brook chart stock was stable whereas ouananiche showed considerable variation in year class strength. Stock estimates were not significantly different for the two species although the brook charr estimate was 1.5 that of the ouananiche. Production estimates differed by a greater margin because of different growth patterns. Brook chair production was estimated at 19.4 kg ha−1 yr−1. Above age 2+ it was 11.4 kg ha−1 yr−1 which compares with 4.8 kg ha−1 yr−1 for the same age groups of ouananiche.
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  • 21
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    Environmental biology of fishes 5 (1980), S. 117-133 
    ISSN: 1573-5133
    Keywords: Cycles ; Communities ; Diversity ; Ecology ; Estuary ; Multiple regressions ; Oceanography ; Salinity ; Seasons ; Time-series analysis
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology
    Notes: Synopsis From November 1975 to April 1977 nocturnal dermersal fish were sampled fortnightly at ten sites in Serpentine Creek using a three meter beam trawl with a 3.2 cm mesh net. Forty-five species from thirty-four families were obtained totalling 14 518 individuals with the six most abundant species comprising approximately 72% of the catch. Using multiple regression techniques with Fourier transformations, the mean number of species (S) and abundance (N) of all fish were found to conform to a regular annual cyclical pattern with maxima in April and May. A trend toward declining abundances of individuals and species was present. Shannon (H′) and Gleason (G) diversity indices showed no regular seasonal trends and are considered poor indicators of pollution. In comparison with other estuarine studies at different latitudes Serpentine Creek conforms to the theory that more tropical waters have the greatest faunal diversity. Seventeen of the 22 most abundant species demonstrated a regular annual cycle of abundance. The number of species, abundance and diversity measures were greatest about 1 km from the mouth of the creek and gradually declined upstream. This was the region with highest macrobenthos diversity and with the most stable abiotic values. Temperature and/or salinity were positively correlated with the abundance of eleven species. The species were placed in five groups according to their periodic characteristics. The proportion of ‘resident’ species was low and this is consistent with Tyler's (1971) theory of temperature stabilized fish assemblages. The known biology of six species is related to their occurrence. Salinity and temperature values in the creek exhibit an annual cycle which preceeds that of Bramble Bay by approximately one month. Rainfall in the watershed was correlated with observed salinity values. It is postulated that salinity is the common feature between temperate and tropical estuaries in the maintenance of community cycles.
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  • 22
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    Environmental biology of fishes 6 (1981), S. 95-103 
    ISSN: 1573-5133
    Keywords: Behavior ; Ecology ; Parental care ; Reproductive cycles ; Colonial nesting ; Etroplus maculatus ; Etroplus suratensis
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology
    Notes: Synopsis The Asian cichlids,Etroplus maculatus (the orange chromide) and E. suratensis (the green chromide) in Sri Lanka reproduce twice during the year when water conditions are favorable for nest construction and maintaining visual contact with offspring. These are the drier premonsoonal and monsoonal seasons when water turbidity decreased and salinity increased. When breeding in isolation orange chromide pairs selected dense vegetation where nests were camouflaged. During the peak breeding cycle (July) orange chromide pairs selected sparse vegetation for nesting as a compromise between survival of young and availability of adult food. These areas were also occupied by foraging non-breeding conspecifics which increased the threat of cannibalism of offspring. Under these pressures most orange chromides nested in colonies which helped decrease both actual and attempted cannibalism. The sympatric green chromide does not forage during nesting and nest site selection was determined mainly by factors favoring offspring survival. Biparental care is exhibited by both species. One member of an orange chromide pair stands guard over offspring while the other leaves the territory to forage — their roles are reversed every few minutes. The total parental investment is equivalent to the full investment of a single parent. Monogamy appears to be maintained by their metabolic constraints. In the green chromide both parents are vigilant over offspring and neither forages thus spending twice as much time in parental investment.
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  • 23
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    Environmental biology of fishes 6 (1981), S. 207-211 
    ISSN: 1573-5133
    Keywords: Fish ; Ecology ; Population density ; Exploitation ; Tagging ; Catch per effort
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology
    Notes: Synopsis Population and exploitation estimates were made from angler recaptures of Chautauqua Lake muskellunge,Esox masquinongy Mitchill. Fish were tagged during Conservation Department studies in 1941–1946, 1961–1965 and 1976–1978. Population estimates of adult fish ranged from one to seven fish per hectare and angler exploitation rates of tagged fish fluctuated from 3.8% to 14.1%. Relative catch indicators suggest a major decline in the lake's muskellunge population during the last decade. Overexploitation, habitat alteration and interspecific competition with recently introduced fish species were cited as probable causes of the decline.
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  • 24
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    Environmental biology of fishes 6 (1981), S. 213-218 
    ISSN: 1573-5133
    Keywords: Australia ; Communities ; Cycles ; Diversity ; Ecology ; Estuary ; Lunar periodicity ; Migration ; Sub-tropics ; Tides
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology
    Notes: Synopsis A series of 10 sites were sampled at new and full moon phases in a vertically homogenous estuary, Serpentine Creek, Queensland, Australia. Forty-five species (14,518 individuals) were caught and analysed using standardized Shannon & Gleason diversity indices, and total number of species and individuals. The coefficients of variation for these values were greater for times than for sites. There were no significant differences between 14 pairs of new and full moon phases fort,t,t, andt, or between mean number of individuals for the 16 most abundant species. If significant variations do exist within months, then experiments should be done between spring and neap tides as this study found no differences between the spring tides associated with new and full moon phases.
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  • 25
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    Environmental biology of fishes 6 (1981), S. 371-375 
    ISSN: 1573-5133
    Keywords: Anguilliformes ; Anguillidae ; Leptocephalus ; Fish larvae ; Horizontal distribution ; Vertical distribution ; Spawning area ; Migration ; Ultrasonic tracking ; Hydrography ; Ecology ; North Atlantic ; Anguilla anguilla ; A. rostrata
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology
    Notes: Synopsis This report presents preliminary results of the 1979 Sargasso Sea expedition from February to May 1979. Information is given on horizontal and vertical distribution of eel larvae and adults, adult eel tracking and pelagic trawling. Related matters such as electrophoretic studies on anguilliform larvae, feeding of eel larvae, predation on leptocephali, occurrence of other anguilliform larvae and hydrography are mentioned.
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  • 26
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    Environmental biology of fishes 7 (1982), S. 177-180 
    ISSN: 1573-5133
    Keywords: Temperature ; Behavior ; Ecology ; Fisheries ; Fish ; Marine juveniles
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology
    Notes: Synopsis Sixteen yearling winter flounder, tested individually for 3-day periods in electronic shuttleboxes, voluntarily occupied an 8–27°C range of temperature, with a modal final thermal preferendum of 18.5°C (mean 18.7°C, median 19°C, midpoint 17.5°C, s.d. 1.9°C, S k + 0.33). The locomotor activity pattern of the yearling fish in the laboratory was markedly nocturnal, with mean hourly nocturnal activity exceeding mean hourly diurnal activity by a factor of 3.4. Maximum activity occurred at 0300 EST, minimum activity at 1400 EST. While activity generally increased with temperature, a local activity minimum occurred at 18.7°C, coinciding with the 24-hour mean final thermal preferendum. Comparison of these laboratory data with previously published field data suggest that behavioral responses to temperature and light play significant roles in determining age- and size-specific differences in seasonal depth stratification and onshore-offshore distributions in this species.
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  • 27
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    Environmental biology of fishes 5 (1980), S. 109-116 
    ISSN: 1573-5133
    Keywords: Bay ; Dispersal ; Ecology ; Egg type ; Fish larvae ; Islands ; Points ; Rocky habitats ; Species turnover
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology
    Notes: Synopsis Reef fish community composition in three segments of a peninsular rocky shoreline in the Gulf of California was estimated over four periods by visual observation. ‘Point’ and ‘bay’ segments had regular and distinct species compositions over most periods while a ‘middle’ segment was least distinct but consistently had the greatest number of species. Compositional change along the peninsula was least regular during the coldest sea temperature period (April). Mean species turnover between segments was highest between point and bay. Within segments, the point had greater compositional predictable composition (lowest species turnover). When species with regular frequency of encounter were classified into ‘point’, ‘middle’, ‘bay’, and ‘no trend’ groups it was found that comparatively more ‘point’ species had pelagic eggs and comparatively more ‘bay’ species had demersal eggs. Beta diversity of rocky-shore fishes along the physical gradient of the Punta Doble peninsula reflects a transition between exposed and protected rocky shoreline communities. The correlated physical environmental characteristics associated with exposed and protected habitats are discussed in relation to diversity regulation and dispersal strategies in reef fishes.
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  • 28
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    Environmental biology of fishes 6 (1981), S. 361-365 
    ISSN: 1573-5133
    Keywords: Mimicry ; Shamming death ; Africa ; Fish ; Chafing ; Predation ; Ecology ; Cyrtocara
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology
    Notes: Synopsis Haplochromis (=Cyrtocara) livingstoni, one of the predatory cichlids of the sand community of Lake Malawi, Africa, occurs at a density of 1.3 individuals per hectare. They are territorial, defending areas 15 m wide by 40 m long along the interface of sand andVallisneria weed beds. Individuals use a ‘death feigning’ hunting pattern to capture prey. From a position of lying on their sides semiburied in the sand, these fish attack small cichlids. During four hours of SCUBA observations three successful attacks from this position were seen. After an attack the small cichlids scatter and the predator moves on toward a new aggregation of fish where it again plays dead. Individuals feign death an average of seven times per thirty minutes watch. Death feigning behavior is initiated in two ways. The fish either 1) is stationary with its ventral surface on or close to the sand, and then falls onto its side, or 2) drops from the water colum into `lying on side' position. The initial behavioral actions of the latter method are similar to chafing behavior. But instead of chafing the sand and rising again off the bottom, the fish plows into the sand and remains immobile. These data further add to the evidence that cichlids are remarkably flexible in their feeding behavior.
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  • 29
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    Environmental biology of fishes 7 (1982), S. 121-136 
    ISSN: 1573-5133
    Keywords: Seasonality ; Predator-prey ; Predator interference ; Turnoverrate ; Diversity ; Ecology
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology
    Notes: Synopsis Development of the fish community on a submerged 16 m barge and variation in fish abundance on nearby transects were surveyed twice monthly for twenty months. A steady increase in abundance was observed for certain fishes on the barge, whereas a few species exhibited distinct seasonal variation on both the barge and transects. Most of the seasonal species settled between March and May. Some seasonal species appeared to be site selective in their settlement and consequently settled juveniles were clumped in their distribution. An abundance of preferred topographical features may be why settlement was relatively high at the study site and indirectly why predators became significantly (r3 = 7.67***, N = 37) more abundant at the study area during the months of maximum prey settlement. Concurrent settlement of several species during the same few months may be important because juveniles become an abundant food source to predators during those few months only. Periodic swamping of predators by abundant juvenile prey may improve the chances for individuals of rarer prey species to be overlooked and therefore be succesfully recruited.
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  • 30
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    Environmental biology of fishes 9 (1983), S. 41-53 
    ISSN: 1573-5133
    Keywords: Artificial reefs ; Competition ; Intermediate disturbance ; Ecology ; Mortality ; Predation ; Recruitment ; Stability
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology
    Notes: Synopsis In January 1977, a record breaking cold spell caused fish kills at Big Pine Key, Florida. Census data collected before and after the cold spell from a series of model reefs constructed in 1975 showed a significant drop in mean number of reef fish species and individuals. Following this disturbance, high recruitment of juveniles occurred, presumably due to reduced competition, predation, or a combination of these. Model and natural patch reef communities examined the summer following the cold spell (1977) were significantly different from those examined the summer before (1976) and the second summer following the cold spell (1978). During the summer of 1977, a significantly smaller mean fish size and a significantly greater mean number of species and individuals were observed. Increased species richness following the cold spell is consistent with the intermediate disturbance hypothesis. Contrary to some theoretical predictions, results suggest reef fish communities are highly resilient to some regional disturbance.
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  • 31
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    Plant and soil 56 (1980), S. 123-139 
    ISSN: 1573-5036
    Keywords: Actinorhizas ; Ecology ; Endophyte distribution ; Hippophaë rhamnoides ; Infective potential ; Nodulation ; Root nodules
    Source: Springer Online Journal Archives 1860-2000
    Topics: Agriculture, Forestry, Horticulture, Fishery, Domestic Science, Nutrition
    Notes: Summary The infective potential (IP) of nodule homogenates from field-grownHippophaë rhamnoides L. ssp.rhamnoides was determined by counting the number of nodules formed on test plants after inoculation with various dilutions of the homogenates. The IP was almost constant,i.e. 105 to 106 per gram of fresh nodule material. Methods to store nodule material without loss of IP were tested. The IP of air-dried nodule powders stored at 6°C hardly decreased during a period of more than a year. Data are presented on the IP of soil samples from sites representing various stages of dune formation. BeforeH. rhamnoides appeared, the IP was low: 1 to 36 nodules were formed on test plants per kg of soil. This low IP was due to low numbers of infective endophyte particles in these soils. During the succession of theH. rhamnoides scrub, the IP of the soil increased, due to the increase in the number of endophyte particles in the soil. Gradually, however, nodulation was limited by other environmental factors. The nature of these factors is discussed.
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    Plant and soil 61 (1981), S. 71-80 
    ISSN: 1573-5036
    Keywords: Ecology ; Fluorescent antibody ; Immunofluorescence ; Rhizobium japonicum ; Rhizosphere ; Root surfaces ; Soybean
    Source: Springer Online Journal Archives 1860-2000
    Topics: Agriculture, Forestry, Horticulture, Fishery, Domestic Science, Nutrition
    Notes: Summary Populations of nativeRhizobium japonicum 123 in the rhizospheres of field and pot grown plants as determined by immunofluorescence were calculated on the basis of root surface area. The density ofR. japonicum 123 on the root fluctuated between a few hundred to over a thousand per square centimeter of root surface. As root volume expanded rapidly, the Rhizobium density fell to less than one hundred per unit area. There was no appreciable effect due to different plant, nitrogen amendment, or addition of another strain ofR. japonicum, on the surface density of the nativeR. japonicum population on roots. Nor did the native population influence the added strain. Direct examination of root surface segments revealed that naturalized rhizobia existed sparsely on root surfaces in the form of short rods. They were observed to be attached sideways or in a polar manner on root hairs, epidermal cells, and at junctions of tap and lateral roots. There was no evidence of specific stimulation of the homologous Rhizobium by the host plant as a prelude to nodulation.
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  • 33
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    Environmental biology of fishes 11 (1984), S. 121-130 
    ISSN: 1573-5133
    Keywords: Ecology ; Habitat ; Feeding ; Age ; Growth ; Reproduction ; Mississippi
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology
    Notes: Synopsis Etheostoma swaini, the gulf darter, was collected from the Black Creek drainage in southern Mississippi (February 1978 – April 1979). The gulf darter generally inhabits small- to moderate-size creeks and occurs over a sand or sandy mud bottom, often in association with aquatic vegetation or a layer of organic debris. Larval dipterans were the most important food items, both numerically and volumetrically. Chironomids were found in 71–100% of the stomachs in all except the unusual March 16 collection. The length frequency distribution and the scale annuli analysis indicated there were three year-classes present in the population at any one time. Fifty-one percent of the specimens taken were less than 12 months old. During the mid-February to late March spawning season gulf darters were most often collected over clean gravel or gravelsand substrates. Laboratory observations suggest that the female burrows into the gravel where the demersal, adhesive eggs are deposited. Female gulf darters significantly outnumbered males at a ratio of 59:41.
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    Environmental biology of fishes 11 (1984), S. 173-190 
    ISSN: 1573-5133
    Keywords: Percidae ; Etheostomatini ; Darters ; Ecomorphology ; Embryology ; Ecology ; Early life history
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology
    Notes: Synopsis The early development of northern logperch, Percina caprodes semifasciata, was examined from an ecological perspective and in relation to the theory of saltatory ontogeny. Steps, the intervals of relative homeostasis, separated by thresholds, rapid switches to new form and function resulting from canalization of changes in the preceeding step, are described and related to environmental factors. Adaptive shifts in growth allometries provided further evidence of the saltatory nature of ontogeny. Logperch eggs are small (1.2 mm diameter), demersal, and adhesive. The simple embryonic respiratory system reflects high oxygen availability on the lotic spawning grounds. Hatching occurs early, relative to other darters, and free embryos are pelagic. The small free embryos presumably drift downstream to lentic areas, where small planktonic food is more abundant. Logperch are therefore nonguarding, open substrate spawning lithopelagophils and, along with other Percina species, have not advanced from ancestral percid reproductive styles. Percina species have generally remained in ancestral habitats-rivers and lakes. The close correlation between developmental patterns of logperch and environmental factors is therefore interpreted as a restriction based on retention of ancestral characteristics, not as evidence of novel adaptations to new habitats.
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    Environmental biology of fishes 11 (1984), S. 277-299 
    ISSN: 1573-5133
    Keywords: Percidae ; Etheostomatini ; Ecomorphology ; Embryology ; Ecology ; Early life history ; Heterochrony
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology
    Notes: Synopsis The early development of rainbow darter, Etheostoma caeruleum, was examined from an ecological perspective. Steps and thresholds of ontogeny to completion of body squammation are defined, and related to environmental factors. Rainbow darter eggs are about 2 mm diameter, considerably larger than those of related logperch (Percina caprodes). The embryonic vitelline respiratory plexus is much more extensive. The pelagic interval characteristic of logperch and ancestral percids is eliminated and onset of exogenous feeding is delayed. The larger larvae of the rainbow darter can begin feeding directly on aquatic insects, and complete their life cycle in streams. Therefore, shifts in the timing of important thresholds (e.g. exogenous feeding) are ecologically important. Furthermore, early maturation and/or delayed bone and scale formation may be responsible for reductions in the lateralis system and scalation in this and other darter species.
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  • 36
    ISSN: 1573-5133
    Keywords: Cichlid ; Ecology ; Behavior ; Evolution ; Tropics ; Polymorphism ; Central America ; Lake Malawi ; Africa
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology
    Notes: Synopsis Cichlasoma citrinellum is a polymorphic species whose individual coloration varies from the dark grey markings typical of the species to yellow, orange, and red. In Lake Jiloá, Nicaragua the depth distribution of these latter, nongrey, golden morphs shows dramatic seasonal variation. In the height of the dry season in February over 50% of the gold morphs occur above 9 m, but as the breeding season approaches they migrate deeper such that less than 7% of the gold population occurs above 9 m at the onset of the breeding season. During the rainy season when breeding occurs most of the gold morphs occur below 15 m. It appears that gold morphs ‘voluntarily’ move into deeper water to breed rather than being aggressively forced deeper by larger, territorial grey morphs as was implied in an earlier paper (McKaye & Barlow 1976). Since the morphs of this species assortatively mate and select different habitats in which to breed, future sympatric splitting of this species is possible. Likely examples of sympatric speciation and of incipient speciation in the family Cichlidae are discussed.
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  • 37
    ISSN: 1573-5133
    Keywords: Fish ; Nematode ; Populations ; Life cycle ; Host factors ; Ecology ; Parasites
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology
    Notes: Synopsis A total of 314 white suckers (Catostomus commersoni) taken monthly during May to December 1975 and in April and May 1976 from southern Lake Huron, Ontario, Canada, were examined forCapillaria catostomi. Prevalence determined from fresh white suckers (66%) was significantly lower than from frozen white suckers (81%). However, there was no significant difference in prevalence ofC. catostomi in samples taken at monthly intervals; in male and female white suckers; or in the age categories. Mean intensity of infection was not significantly different in fresh (9.6 [± 13.41]) or frozen (10.4 [± 13.11]) white suckers. There was no significant difference in intensities between monthly samples in male and female white suckers or in the age categories. Suckers were infected with 1–172 worms. The percentage of male, female and immature worms did not change with sex or age of host or by month. The frequency distribution showed the parasites were overdispersed. A possible life cycle forC. catostomi involving an oligochaete intermediate host is discussed and an attempt made to explain the almost constant levels of prevalence and intensity.
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  • 38
    ISSN: 1432-1955
    Keywords: Argas persicus ; Bionomics ; Ecology
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Notes: Abstract The fowl tickArgas (Persicargas) persicus occurs in warm areas of Slovakia, where its distribution is limited by the 650–700 mm annual average isohyet and the +8° C annual average isotherm. In Slovakia, larvae hatch from spring to autumn, and nymphal and adult moultings occur chiefly in July and August. Larvae feed for four days, nymphs and adults for less than one hour. The tick develops and reproduces during the warm season in the wild but throughout the year under favourable laboratory conditions in which the life cycle requires 17 months.
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  • 39
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    Publication Date: 1980-05-30
    Description: 〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Brownell, R L Jr -- Omura, H -- New York, N.Y. -- Science. 1980 May 30;208(4447):976.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/7189604" target="_blank"〉PubMed〈/a〉
    Keywords: Animals ; Humans ; Japan ; Meat/*analysis ; Organomercury Compounds/*analysis ; Whales
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    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
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    American Association for the Advancement of Science (AAAS)
    Publication Date: 1980-10-31
    Description: Timing of the repetitive movements that constitute any rhythmic behavior is regulated by intrinsic properties of the central nervous system rather than by sensory feedback from moving parts of the body. Evidence of this permits resolution of the long-standing controversy over the neural basis of rhythmic behavior and aids in the identification of this mechanism as a general principle of neural organization applicable to all animals with central nervous systems.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Delcomyn, F -- NS 15632/NS/NINDS NIH HHS/ -- S07 RR 7030/RR/NCRR NIH HHS/ -- New York, N.Y. -- Science. 1980 Oct 31;210(4469):492-8.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/7423199" target="_blank"〉PubMed〈/a〉
    Keywords: Animals ; Behavior, Animal/*physiology ; Biological Clocks ; Central Nervous System/physiology ; Feedback ; Locomotion ; Mastication ; *Nervous System Physiological Phenomena ; *Periodicity ; Peripheral Nerves/physiology ; Respiration ; Vocalization, Animal/physiology
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  • 41
    Publication Date: 1980-06-27
    Description: The enzyme NADPH-cytochrome c (P-450) reductase was identified by indirect immunofluorescence in hepatocytes, bronchioles, and proximal tubules of liver, lung, and kidney, respectively, of rats and minipigs that had been injected with phenobarbital or saline. The distribution of this component of the cytochrome P-450-mediated microsomal system may be relevant to sites of drug toxicity and carcinogenesis.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Dees, J H -- Coe, L D -- Yasukochi, Y -- Masters, B S -- New York, N.Y. -- Science. 1980 Jun 27;208(4451):1473-5.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/6770464" target="_blank"〉PubMed〈/a〉
    Keywords: Animals ; Fluorescent Antibody Technique ; Kidney/drug effects/*enzymology ; Liver/drug effects/*enzymology ; Lung/drug effects/*enzymology ; Male ; NADPH-Ferrihemoprotein Reductase/*metabolism ; Organ Specificity ; Phenobarbital/*pharmacology ; Rats
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  • 42
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    Publication Date: 1980-03-07
    Description: Antiserum specific for purified canine renal renin was used to inhibit this enzyme in trained, conscious dogs. The antiserum did not affect blood pressure in sodium-replete dogs but decreased plasma renin activity and blood pressure in sodium-depleted animals. The antiserum also reduced blood pressure to control levels concomitant with suppression of plasma renin activity in uninephrectomized dogs with acute renovascular hypertension. These observations establish the role of the renin-angiotensin system in the maintenance of blood pressure in the sodium-depleted state as well as in the initiation of renovascular hypertension.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Dzau, V J -- Kopelman, R I -- Barger, A C -- Haber, E -- New York, N.Y. -- Science. 1980 Mar 7;207(4435):1091-3.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/6986653" target="_blank"〉PubMed〈/a〉
    Keywords: Animals ; Antibody Specificity ; Antigen-Antibody Reactions ; *Blood Pressure ; Diet, Sodium-Restricted ; Dogs ; Homeostasis ; Hypertension, Renal/*enzymology ; Hypertension, Renovascular/*enzymology ; Immunologic Techniques ; Kidney/blood supply ; Renin/antagonists & inhibitors/blood/*immunology ; Vascular Resistance
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  • 43
    Publication Date: 1980-05-02
    Description: The highly selective, enzyme-activated, irreversible inhibitor of L-ornithine decarboxylase, DL-alpha-difluoromethylornithine, suppresses the increase in uterine L-ornithine decarboxylase activity associated with early embryogenesis in the mouse and arrests embryonic development at that stage. Contragestational effects were confirmed in the rat and rabbit. An increase in L-ornithine decarboxylase activity that leads to a rapid increase in putrescine concentration appears to be essential during a critical period after implantation for continued mammalian embryonal growth.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Fozard, J R -- Part, M L -- Prakash, N J -- Grove, J -- Schechter, P J -- Sjoerdsma, A -- Koch-Weser, J -- New York, N.Y. -- Science. 1980 May 2;208(4443):505-8.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/6768132" target="_blank"〉PubMed〈/a〉
    Keywords: Adenosylmethionine Decarboxylase/metabolism ; Animals ; Carboxy-Lyases/*physiology ; Eflornithine ; Embryo, Mammalian/drug effects/*physiology ; Female ; Gestational Age ; Mice ; Ornithine/*analogs & derivatives/pharmacology ; Ornithine Decarboxylase/*physiology ; Ornithine Decarboxylase Inhibitors ; Polyamines/metabolism ; Pregnancy ; Rabbits ; Rats ; Uterus/drug effects/*metabolism
    Print ISSN: 0036-8075
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  • 44
    Publication Date: 1980-11-07
    Description: An analog of luteinizing hormone-releasing hormone containing a gamma-lactam as a conformational constraint has been prepared with the use of a novel cyclization of a methionine sulfonium salt. The analog is more active as a luteinizing hormone-releasing hormone agonist that the parent hormone, and provides evidence for a bioactive conformation containing a beta-turn.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Freidinger, R M -- Veber, D F -- Perlow, D S -- Brooks, J R -- Saperstein, R -- New York, N.Y. -- Science. 1980 Nov 7;210(4470):656-8.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/7001627" target="_blank"〉PubMed〈/a〉
    Keywords: Amino Acid Sequence ; Animals ; Biological Assay ; Cells, Cultured ; Female ; *Gonadotropin-Releasing Hormone/analogs & derivatives ; Hydrogen Bonding ; Lactams ; Protein Conformation ; Rats ; Structure-Activity Relationship
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  • 45
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    American Association for the Advancement of Science (AAAS)
    Publication Date: 1980-03-21
    Description: Intensive research in the last decade has revealed a wealth of detail on the mechanism of biosynthesis, molecular structure, and covalent cross-linking of collagen. Tissues of higher animals express a family of at least five genetically distinct types of collagen molecule, each apparently tailored for different construction work outside the cell. Within each genetic type of collagen, further chemical heterogeneity is also evident; the variations in hydroxylation, glycosylation, and cross-linking are dependent, for example, on tissue type, age, and hormonal status. The functional significance of collagen's molecular diversity and its control by different cells and tissues are not yet well understood but abnormalities of collagen in many human diseases keep this protein a focal molecule of medical research.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Eyre, D R -- New York, N.Y. -- Science. 1980 Mar 21;207(4437):1315-22.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/7355290" target="_blank"〉PubMed〈/a〉
    Keywords: Amino Acid Sequence ; Animals ; Calcification, Physiologic ; Cartilage/ultrastructure ; *Collagen/genetics/metabolism ; Epithelium/ultrastructure ; Extracellular Space/ultrastructure ; Humans ; Hydrogen Bonding ; Polymorphism, Genetic ; Protein Biosynthesis ; Protein Conformation ; Vertebrates
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  • 46
    Publication Date: 1980-05-30
    Description: Neurons in deep laminae of the rabbit cingulate cortex develop discriminative activity at an early stage of behavioral discrimination learning, whereas neurons in the anteroventral nucleus of thalamus and neurons in the superficial cortical laminae develop such activity in a late stage of behavioral learning. It is hypothesized that early-forming discriminative neuronal activity, relayed to anteroventral neurons via the corticothalamic pathway, contributes to the construction of changes underlying the late-forming neuronal discrimination in the anteroventral nucleus. The resultant late discriminative activity in the anteroventral nucleus is then relayed via the thalamocortical pathway back to the superficial cortical laminae, promoting disengagement of cortex from further task-processing.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Gabriel, M -- Foster, K -- Orona, E -- New York, N.Y. -- Science. 1980 May 30;208(4447):1050-2.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/7375917" target="_blank"〉PubMed〈/a〉
    Keywords: Animals ; Avoidance Learning/*physiology ; Brain Mapping ; Cerebral Cortex/cytology/*physiology ; Discrimination (Psychology)/*physiology ; Gyrus Cinguli/*physiology ; Neural Pathways/physiology ; Rabbits ; Thalamus/*physiology ; Time Factors
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  • 47
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    American Association for the Advancement of Science (AAAS)
    Publication Date: 1980-08-08
    Description: 〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Garcia-Bunuel, L -- New York, N.Y. -- Science. 1980 Aug 8;209(4457):720-1.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/7394536" target="_blank"〉PubMed〈/a〉
    Keywords: Animals ; Caudate Nucleus/physiology ; Gallamine Triethiodide/*pharmacology ; Receptors, Dopamine/drug effects/*physiology ; Synapses/drug effects/*physiology
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  • 48
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    American Association for the Advancement of Science (AAAS)
    Publication Date: 1980-02-08
    Description: The distribution of active polyadenylate-messenger RNA sequences in fractionated chicken liver chromatin was examined. A portion of these active gene sequences is concentrated in a DNA fraction retained by tightly bound nonhistone chromosomal proteins, while the nonretained DNA fraction is substantially depleted of a portion of these sequences. These findings suggest that the tightly bound nonhistones are physically associated with a subset of active gene sequences.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Gates, D M -- Bekhor, I -- New York, N.Y. -- Science. 1980 Feb 8;207(4431):661-2.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/7352280" target="_blank"〉PubMed〈/a〉
    Keywords: Animals ; Base Sequence ; Chickens ; Chromatin/ultrastructure ; Chromosomal Proteins, Non-Histone/*metabolism ; DNA/*metabolism ; *Genes ; Liver/*metabolism ; Nucleic Acid Hybridization ; Protein Binding ; RNA, Messenger/genetics ; Sodium Chloride
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  • 49
    Publication Date: 1980-05-02
    Description: Amphibians of the family Bufonidae contain high levels of skin compounds that both inhibit Na+- and K+-dependent adenosinetriphosphatase and antagonize the binding of ouabain to the enzyme. In species of Bufo and Atelopus, these compounds are relatively nonpolar bufodienolides, whereas Dendrophryniscus and Melanophryniscus contain more polar compounds of unknown structure. Skin extracts from 30 of 48 species of frogs representing an additional eight families contained relatively low levels of compounds that inhibit binding of ouabain to Na+,K+-adenosinetriphosphatase. The widespread occurrence of low levels of inhibitory compounds is consonant with the role for these compounds as physiological regulators of Na+,K+-adenosinetriphosphatase in amphibian skin; high levels in the Bufonidae probably also serve as a defense against some predators.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Flier, J -- Edwards, M W -- Daly, J W -- Myers, C W -- New York, N.Y. -- Science. 1980 May 2;208(4443):503-5.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/6245447" target="_blank"〉PubMed〈/a〉
    Keywords: Animals ; Anura/*metabolism ; Binding Sites ; Bufanolides/pharmacology ; Ouabain/antagonists & inhibitors/*metabolism ; Skin/analysis/enzymology/*metabolism ; Sodium-Potassium-Exchanging ATPase/*metabolism ; Species Specificity ; Tissue Extracts/pharmacology
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  • 50
    Publication Date: 1980-11-07
    Description: Cytochemical staining of demyelinated peripheral axons revealed two types of axon membrane organization, one of which suggests that the demyelinated axolemma acquires a high density of sodium channels. Ferric ion-ferrocyanide stain was confined to a restricted region of axon membrane at the beginning of a demyelinated segment or was distributed throughout the demyelinated segment of axon. The latter pattern represents one possible morphological correlate of continuous conduction through a demyelinated segment and suggests a reorganization of the axolemma after demyelination.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Foster, R E -- Whalen, C C -- Waxman, S G -- NS-15320/NS/NINDS NIH HHS/ -- New York, N.Y. -- Science. 1980 Nov 7;210(4470):661-3.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/6159685" target="_blank"〉PubMed〈/a〉
    Keywords: Animals ; Demyelinating Diseases/metabolism/*pathology ; Disease Models, Animal ; Ion Channels/*metabolism ; Male ; Neural Conduction ; Neurilemma/*metabolism/pathology ; Rats ; Staining and Labeling
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  • 51
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    American Association for the Advancement of Science (AAAS)
    Publication Date: 1980-10-01
    Description: 〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Fox, M W -- New York, N.Y. -- Science. 1980 Oct;210(4468):376-9.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/7433981" target="_blank"〉PubMed〈/a〉
    Keywords: *Animal Feed ; Animals ; Anti-Bacterial Agents/*adverse effects ; Food Additives/adverse effects ; Swine
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  • 52
    Publication Date: 1980-01-11
    Description: A new N-methylpurine riboside (doridosine), probably N1-Methylisoguanosine, was isolated from the digestive glands of a nudibranch. Doridosine produces prolonged hypotension and bradycardia in anesthetized rats, decreases the rate and the amplitude of contraction of guinea pig atria in vitro, and causes the heart rate in anesthetized mice to be reduced by 50 percent for many hours after which the animals recover completely.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Fuhrman, F A -- Fuhrman, G J -- Kim, Y H -- Pavelka, L A -- Mosher, H S -- New York, N.Y. -- Science. 1980 Jan 11;207(4427):193-5.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/7350655" target="_blank"〉PubMed〈/a〉
    Keywords: Animals ; Antihypertensive Agents/*isolation & purification ; Guanosine/*analogs & derivatives/isolation & purification/pharmacology ; Guinea Pigs ; Heart Rate/drug effects ; Mice ; Mollusca/analysis ; Rats
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  • 53
    Publication Date: 1980-05-02
    Description: Analysis of extracts of the bloodstream forms of Trypanosoma brucei showed that both DNA polymerase-alpha and DNA polymerase-beta activities were present. The detection of DNA polymerase-beta in T. brucei demonstrates the presence of this enzyme in unicellular organisms. DNA polymerase-beta is present also in Leishmania mexicana. The DNA polymerases in T. brucei are immunologically distinct from the host enzymes. The structural differences between the parasite and the host enzymes could be exploited for the development of agents to combat parasitic diseases.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Chang, L M -- Cheriathundam, E -- Mahoney, E M -- Cerami, A -- New York, N.Y. -- Science. 1980 May 2;208(4443):510-1.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/7367875" target="_blank"〉PubMed〈/a〉
    Keywords: Animals ; Centrifugation, Density Gradient ; Chickens ; DNA Polymerase I/analysis ; DNA Polymerase II/analysis ; DNA Polymerase III/analysis ; DNA-Directed DNA Polymerase/*analysis ; Fishes ; Immune Sera ; Leishmania/*enzymology ; Molecular Weight ; Rabbits ; Rats ; Species Specificity ; Trypanosoma brucei brucei/*enzymology
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  • 54
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    American Association for the Advancement of Science (AAAS)
    Publication Date: 1980-06-27
    Description: A discussion of drug-receptor theory is used to show that the three-dimensional structure, or shape, of molecules is important for biological activity. The computer-assisted molecular modeling system at Merck is described, and it is shown that this system is useful for generating and storing molecular structures, determining preferred conformation, comparing molecular shapes, and computing molecular properties. Applications of the system to the study of anti-inflammatory drugs, somatostatin-like compounds, and dihydrofolate reductase inhibitors are summarized.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Gund, P -- Andose, J D -- Rhodes, J B -- Smith, G M -- New York, N.Y. -- Science. 1980 Jun 27;208(4451):1425-31.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/6104357" target="_blank"〉PubMed〈/a〉
    Keywords: Animals ; Arachidonic Acids ; Binding Sites ; Computers ; Cyclooxygenase Inhibitors ; Humans ; Indomethacin ; *Models, Molecular ; *Models, Structural ; *Molecular Conformation ; *Pharmaceutical Preparations ; Receptors, Drug/metabolism ; Somatostatin/analogs & derivatives ; Structure-Activity Relationship
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  • 55
    Publication Date: 1980-04-25
    Description: In BALB/c female mice with melanoma transplants, the incidence of "takes" is decreased and survival is increased by hydroquinone, a melanocytolytic agent. The mechanism of drug action is suggested by via DNA. The significant and high degree of positive response to hydroquinone treatment in vivo is encouraging for the clinical management of melanoma with melanocytolytic agents.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Chavin, W -- Jelonek, E J Jr -- Reed, A H -- Binder, L R -- New York, N.Y. -- Science. 1980 Apr 25;208(4442):408-10.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/7367868" target="_blank"〉PubMed〈/a〉
    Keywords: Animals ; Disease Models, Animal ; Dose-Response Relationship, Drug ; Female ; Hydroquinones/metabolism/*therapeutic use ; Melanocytes/metabolism ; Melanoma/*drug therapy ; Mice ; Neoplasm Transplantation ; Neoplasms, Experimental/drug therapy
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  • 56
    Publication Date: 1980-04-04
    Description: Lysyl oxidase activity was found in the isthmus (the membrane-forming region) of the hen's oviduct in a copper-rich region proximal to the shell gland. Desmosine and isodesmosine, cross-linking compounds associated with mature elastin, were found in hydrolysates of the shell membrane, confirming the necessity for lysyl oxidase in its biosynthesis. Shell membranes from hens fed a copper-deficient diet or a diet supplemented with beta-aminopropionitrile had a reduced content of desmosine and isodesmosine.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Harris, E D -- Blount, J E -- Leach, R M Jr -- New York, N.Y. -- Science. 1980 Apr 4;208(4439):55-6.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/6102412" target="_blank"〉PubMed〈/a〉
    Keywords: Amino Acid Oxidoreductases/*metabolism ; Animals ; Chickens/*metabolism ; Copper/metabolism ; Cross-Linking Reagents ; Desmosine/analysis ; *Egg Shell ; Isodesmosine/analysis ; Oviducts/*enzymology ; Protein-Lysine 6-Oxidase/*metabolism
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  • 57
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    American Association for the Advancement of Science (AAAS)
    Publication Date: 1980-11-07
    Description: Lanosterol, a cholesterol precursor that increases considerably in the platelets of rats treated with oral contraceptives, was incubated with either platelet-rich plasma or washed platelet suspension. After 2 minutes there was a remarkable dose-related increase in platelet activity. This platelet hyperactivity was measured by clotting time and platelet aggregation could not be reproduced by cholesterol or ethinylestradiol.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Ciavatti, M -- Dumont, E -- Benoit, C -- Renaud, S -- New York, N.Y. -- Science. 1980 Nov 7;210(4470):642-4.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/7433990" target="_blank"〉PubMed〈/a〉
    Keywords: Animals ; Blood Coagulation/*drug effects ; Blood Platelets/*drug effects ; Contraceptives, Oral/*pharmacology ; Dose-Response Relationship, Drug ; Female ; Lanosterol/*pharmacology ; Platelet Aggregation/*drug effects ; Rats
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  • 58
    Publication Date: 1980-09-05
    Description: The flavin adenine dinucleotide--dependent monooxygenase in mammalian hepatic microsomes plays a major role in the oxidative metabolism of thioether-containing pesticides. Thirty-four compounds were tested, and it was determined that organophosphorus insecticides such as disulfoton and phorate are rapidly oxidized by the purified enzyme to their corresponding sulfoxides. The enzyme does not catalyze the oxidation of the thiophosphoryl and thiol sulfur atoms of these or other phosphorothioates and phosphorodithioates, or the oxidation of the sulfoxide to the sulfone. Carbamates aldicarb and Croneton are also oxidized, but at a lower rate.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Hajjar, N P -- Hodgson, E -- New York, N.Y. -- Science. 1980 Sep 5;209(4461):1134-6.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/7403873" target="_blank"〉PubMed〈/a〉
    Keywords: Aniline Compounds/metabolism ; Animals ; Biotransformation ; Microsomes, Liver/enzymology/*metabolism ; Oxidation-Reduction ; Oxygenases/*metabolism ; Pesticides/*metabolism ; Substrate Specificity ; Sulfur ; Swine
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  • 59
    Publication Date: 1980-12-05
    Description: A new dopamine analog, 6,7-dihydroxy-2-dimethylaminotetralin (TL-99), was compared to apomorphine in three tests of dopaminergic function in the central nervous system. The tests, performed on rats, included production of changes in locomotor activity (involving both presynaptic and postsynaptic receptors), inhibition of dopa accumulation (quantifying presynaptic receptor activity), and the rotation model (quantifying postsynaptic receptor activation). Apomorphine was efficacious at both presynaptic and postsynaptic receptors, whereas TL-99 was much more efficacious at the presynaptic receptor. This result indicates not only that differences exist between presynaptic and postsynaptic dopamine receptors, but also that these differences may be exploited in the design of selective dopamine agonists.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Goodale, D P -- Rusterholz, D B -- Long, J P -- Flynn, J R -- Walsh, B -- Cannon, J G -- Lee, T -- GM 12675/GM/NIGMS NIH HHS/ -- GM-22365/GM/NIGMS NIH HHS/ -- New York, N.Y. -- Science. 1980 Dec 5;210(4474):1141-3.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/7444443" target="_blank"〉PubMed〈/a〉
    Keywords: Animals ; Apomorphine/pharmacology ; Behavior, Animal/drug effects ; Brain/*drug effects ; Levodopa/metabolism ; Motor Activity/drug effects ; Naphthols ; Rats ; Receptors, Dopamine/*drug effects ; Synaptic Membranes/*drug effects ; *Tetrahydronaphthalenes
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  • 60
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    American Association for the Advancement of Science (AAAS)
    Publication Date: 1980-04-04
    Description: A new transport mechanism explains the importance of the shape of bronchial bifurcations in the transfer of gases and particles between the atmosphere and the alveoli. Photographs of flow visualization experiments illustrate the effect in models of bronchial branching. The mechanism provides a means of nondiffusional transport that helps to explain normal respiratory exchange of gases as well as successful ventilation with very low tidal volumes, as in some lung diseases and in the high-frequency panting of dogs.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Haselton, F R -- Scherer, P W -- New York, N.Y. -- Science. 1980 Apr 4;208(4439):69-71.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/7361109" target="_blank"〉PubMed〈/a〉
    Keywords: Animals ; Bronchi/*anatomy & histology/physiology ; Humans ; *Respiration ; Tidal Volume
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  • 61
    Publication Date: 1980-03-21
    Description: The indirect method of immunofluorescence was used to demonstrate the presence of amelogenins in the enameloid of teeth and dermal denticles of Chondrichthyes; in the enameloid of Teleostei and Amphibia; and in the enamel of Reptilia. Nonmammalian amelogenins are formed in the ectodermal cells of tooth organs and chemically are so similar to mammalian amelogenins that they interact with antiserum prepared from bovine enamel matrix.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Herold, R C -- Graver, H T -- Christner, P -- New York, N.Y. -- Science. 1980 Mar 21;207(4437):1357-8.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/6986656" target="_blank"〉PubMed〈/a〉
    Keywords: Amelogenesis ; Animals ; Dental Enamel Proteins/immunology/*metabolism ; Fluorescent Antibody Technique ; Species Specificity ; Tooth/*anatomy & histology ; Vertebrates/*anatomy & histology
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  • 62
    Publication Date: 1980-12-19
    Description: Anglerfish (Lophius americanus) insulin complementary DNA was cloned in bacterial plasmids, and its sequence was determined. Fish insulin messenger RNA is larger (1.5 times) than the messenger RNA encoding mammalian (rat and human) insulin, in part because of a larger C peptide (an additional six amino acids or 18 nucleotides in length) but mainly because of increases in the 5' and 3' untranslated regions. Comparison of the fish, rat, and human insulin messenger RNA (from the complementary DNA) reveals that, in addition to the regions coding for the A and B peptides, sequence conservation is limited to a segment within the 5' untranslated region which may be involved in ribosomal binding, two small segments of the signal peptide, and two stretches of sequence in the 3' untranslated region.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Hobart, P M -- Shen, L P -- Crawford, R -- Pictet, R L -- Rutter, W J -- AM 21344/AM/NIADDK NIH HHS/ -- New York, N.Y. -- Science. 1980 Dec 19;210(4476):1360-3.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/7001633" target="_blank"〉PubMed〈/a〉
    Keywords: Amino Acid Sequence ; Animals ; *Biological Evolution ; Cloning, Molecular ; Codon ; Fishes/*genetics ; Insulin/*genetics ; Nucleic Acid Conformation ; Proinsulin/genetics ; Protein Biosynthesis ; Protein Precursors/genetics ; RNA, Messenger/*genetics
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  • 63
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    American Association for the Advancement of Science (AAAS)
    Publication Date: 1980-09-05
    Description: Many types of cells methylate phospholipids using two methyltransferase enzymes that are asymmetrically distributed in membranes. As the phospholipids are successively methylated, they are translocated from the inside to the outside of the membrane. When catecholamine neurotransmitters, lectins, immunoglobulins or chemotaxic peptides bind to the cell surface, they stimulate the methyltransferase enzymes and reduce membrane viscosity. The methylation of phospholipids is coupled to Ca2+ influx and the release of arachidonic acid, lysophosphatidylcholine, and prostaglandins. These closely associated biochemical changes facilitate the transmission of many signals through membranes, resulting in the generation of adenosine 3',5'-monophophate in many cell types, release of histamine in mast cells and basophils, mitogenesis in lymphocytes, and chemotaxis in neutrophils.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Hirata, F -- Axelrod, J -- New York, N.Y. -- Science. 1980 Sep 5;209(4461):1082-90.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/6157192" target="_blank"〉PubMed〈/a〉
    Keywords: Adrenal Medulla/metabolism ; Animals ; Arachidonic Acids/metabolism ; Calcium/metabolism ; Cell Membrane/metabolism ; Chemotaxis, Leukocyte ; Histamine Release ; Lymphocyte Activation ; *Membrane Fluidity ; Membrane Lipids/*metabolism ; Methylation ; Phosphatidylcholines/metabolism ; Phosphatidylethanolamines/metabolism ; Phospholipids/*metabolism ; Rats ; Receptors, Adrenergic, beta/metabolism ; Receptors, Drug/*physiology ; S-Adenosylmethionine/metabolism
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  • 64
    Publication Date: 1980-01-04
    Description: Morphine and beta-endorphin inhibit the shaking response of pentobarbital-anesthetized rats to ice water. Stereotaxically guided administration of antibodies to cerebroside sulfate into the periaqueductal gray region, the most sensitive brain region in which to demonstrate inhibition of this response, antagonizes the effect of morphine and beta-endorphin. These results suggest that cerebroside sulfate may be an integral component of an opiate receptor in rat brain.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Craves, F B -- Zalc, B -- Leybin, L -- Baumann, N -- Loh, H H -- New York, N.Y. -- Science. 1980 Jan 4;207(4426):75-6.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/6243189" target="_blank"〉PubMed〈/a〉
    Keywords: Animals ; Antigen-Antibody Reactions ; Behavior, Animal/drug effects ; Biological Assay ; Brain/*immunology ; Cerebral Aqueduct ; Endorphins/*antagonists & inhibitors ; Male ; Morphine/*antagonists & inhibitors ; Pentobarbital/pharmacology ; Rats ; Receptors, Opioid/*immunology ; Sulfoglycosphingolipids/*immunology
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  • 65
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    American Association for the Advancement of Science (AAAS)
    Publication Date: 1980-02-29
    Description: A virus was isolated from an adult goat with chronic arthritis and shown to belong to the retrovirus group by electron microscopy and biochemical methods. Inoculation of the virus into cesarean-derived specific-pathogen-free goats' kids produced arthritic lesions similar to those in the spontaneous disease. Vrus was reisolated from the experimentally induced lesions.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Crawford, T B -- Adams, D S -- Cheevers, W P -- Cork, L C -- New York, N.Y. -- Science. 1980 Feb 29;207(4434):997-9.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/6153243" target="_blank"〉PubMed〈/a〉
    Keywords: Animals ; Arthritis, Infectious/microbiology/*veterinary ; Encephalomyelitis/microbiology/*veterinary ; Goats/*microbiology ; RNA-Directed DNA Polymerase/metabolism ; Retroviridae/ultrastructure ; Virus Diseases/complications/transmission/*veterinary
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  • 66
    Publication Date: 1980-10-10
    Description: Photosynthesis of previtamin D3 can occur throughout the epidermis in the dermis when hypopigmented Caucasian skin is exposed to solar ultraviolet radiation. Once previtamin D3 is formed in the skin, it undergoes a temperature-dependent thermal isomerization that takes at least 3 days to complete. The vitamin D-binding protein preferentially translocates the thermal product, vitamin D3, into the circulation. These processes suggest a unique mechanism for the synthesis, storage, and slow, steady release of vitamin D3 from the skin into the circulation.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Holick, M F -- MacLaughlin, J A -- Clark, M B -- Holick, S A -- Potts, J T Jr -- Anderson, R R -- Blank, I H -- Parrish, J A -- Elias, P -- AM25395-01/AM/NIADDK NIH HHS/ -- AM27334-01/AM/NIADDK NIH HHS/ -- New York, N.Y. -- Science. 1980 Oct 10;210(4466):203-5.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/6251551" target="_blank"〉PubMed〈/a〉
    Keywords: Animals ; Carrier Proteins/metabolism ; Cholecalciferol/*biosynthesis ; Cholestadienols/*biosynthesis ; Dose-Response Relationship, Radiation ; Hot Temperature ; Humans ; Isomerism ; Photochemistry ; Rats ; Skin/cytology/*metabolism ; Ultraviolet Rays ; Vitamin D/metabolism ; Vitamin D-Binding Protein
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  • 67
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    American Association for the Advancement of Science (AAAS)
    Publication Date: 1980-07-11
    Description: Synthetic metal complexes can closely approach the properties of metal ions in proteins and yield useful information concerning biological structure and function.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Ibers, J A -- Holm, R H -- New York, N.Y. -- Science. 1980 Jul 11;209(4453):223-35.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/7384796" target="_blank"〉PubMed〈/a〉
    Keywords: Animals ; Binding Sites ; Electron Transport ; Humans ; Iron-Sulfur Proteins ; *Metalloproteins ; *Metals ; Molecular Conformation ; Myoglobin ; Oxygen/blood ; Oxyhemoglobins ; Protein Binding ; Protein Conformation
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  • 68
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    American Association for the Advancement of Science (AAAS)
    Publication Date: 1980-10-03
    Description: Both natural (-)-morphine and its unnatural enantiomer (+)-morphine exert an excitatory action on electrically stimulated contractions of rat vas deferens. Preexposure to (-)-morphine results in cross-tolerance to the inhibitory action of beta-endorphin. (-)-Naloxone and its stereoisomer (+)-naloxone also exert an excitatory action, but only (-)-naloxone bocks the inhibtory action of beta-endorphin. Thus morphine exerts a dual action on a peripheral organ: one an inhibitory action mediated by the stereospecific endorphin receptor that is blocked stereospecifically by naloxone, the other an excitatory action mediated by a nonstereospecific receptor that is not blocked by naloxone. The opiate abstinence syndrome is seen as due to the unmasking of the excitatory action of opiates when its concomitant inhibitory influence is removed by selective blockade by naloxone or weakened by selective tolerance. The view that the rat vas deferens is devoid of morphine receptors is now seen as arising from a reverse example of morphine's dual action: the masking of the inhibitory action of morphine by its concomitant and more potent excitatory action.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Jacquet, Y F -- DA 00367/DA/NIDA NIH HHS/ -- New York, N.Y. -- Science. 1980 Oct 3;210(4465):95-7.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/6158098" target="_blank"〉PubMed〈/a〉
    Keywords: Animals ; Drug Interactions ; Endorphins/pharmacology ; Male ; Morphine/antagonists & inhibitors/pharmacology ; Muscle Contraction/drug effects ; Naloxone/pharmacology ; Narcotics/*pharmacology ; Rats ; Receptors, Opioid/drug effects ; Stereoisomerism ; Substance P/pharmacology ; Vas Deferens/*drug effects
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  • 69
    Publication Date: 1980-12-05
    Description: Comparison was made of the distribution of the insulin receptor sites on adipocyte and liver plasma membranes by using ferritin-insulin. Two-thirds of the occupied insulin receptors on adipocytes occurred in groups of two or more whereas up to two-thirds of the receptors on liver occurred as single receptors. Ferritin-insulin did not cause aggregation of the receptor sites in either tissue. The naturally occurring groups of receptors on adipocyte membranes may play a role in the greater sensitivity of adipocytes to insulin.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Jarett, L -- Schweitzer, J B -- Smith, R M -- AM 20097/AM/NIADDK NIH HHS/ -- T32 AM 07296/AM/NIADDK NIH HHS/ -- New York, N.Y. -- Science. 1980 Dec 5;210(4474):1127-8.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/7003710" target="_blank"〉PubMed〈/a〉
    Keywords: Adipose Tissue/*ultrastructure ; Animals ; Cell Membrane/ultrastructure ; Insulin/metabolism ; Liver/*ultrastructure ; Macromolecular Substances ; Membrane Fluidity ; Oxidation-Reduction ; Protein Binding ; Rats ; *Receptor, Insulin/metabolism ; Sulfhydryl Compounds
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  • 70
    Publication Date: 1980-11-21
    Description: A hormonally defined medium was used to isolate a homogeneous epithelioid cell population from canine kidney. Monolayers of these cells form domes, an indication of active ion transport, and this process is inhibited by ouabain. This technique allows the isolation of primary cultures of renal epithelial cells, free of fibroblasts, for the characterization of biochemical and physiological properties related to renal function.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Jefferson, D M -- Cobb, M H -- Gennaro, J F Jr -- Scott, W N -- New York, N.Y. -- Science. 1980 Nov 21;210(4472):912-4.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/7434005" target="_blank"〉PubMed〈/a〉
    Keywords: Animals ; Biological Transport, Active ; Cell Adhesion ; Cells, Cultured ; Culture Media ; Dogs ; Epithelium/metabolism ; Female ; Kidney/*cytology ; Male ; Sodium/metabolism
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  • 71
    Publication Date: 1980-11-21
    Description: Rats and guinea pigs, when immunized with mouse nerve growth factor, produce antibodies that cross-react with their own nerve growth factor. The antibodies reach developing offspring of these animals both prenatally (rats and guinea pigs) and postnatally (rats). Depriving the fetus of nerve growth factor in this way results in the destruction of up to 85 percent of dorsal root ganglion neurons as well as destruction of sympathetic neurons. Sensory neurons of placodal origin in the nodose ganglion were not affected. These data demonstrate that dorsal root ganglion neurons go through a phase of nerve growth factor dependence in vivo.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Johnson, E M Jr -- Gorin, P D -- Brandeis, L D -- Pearson, J -- HD12260/HD/NICHD NIH HHS/ -- HL20604/HL/NHLBI NIH HHS/ -- New York, N.Y. -- Science. 1980 Nov 21;210(4472):916-8.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/7192014" target="_blank"〉PubMed〈/a〉
    Keywords: Animals ; *Antibodies ; Female ; Ganglia, Spinal/cytology/*embryology/growth & development ; Guinea Pigs ; Lactation ; Maternal-Fetal Exchange ; Milk/immunology ; Nerve Growth Factors/*immunology ; Pregnancy ; Rats
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  • 72
    Publication Date: 1980-10-31
    Description: Treatment of pregnant rats with reserpine prevented the normal disappearance of catecholamine fluorescence in presumptive neuroblasts of the embryonic gut. These cells normally express the noradrenergic phenotype transiently during embryonic development. The effect of reserpine was reproduced by treating mothers with hydrocortisone acetate. Moreover, the reserpine effect was blocked by treatment with dexamethasone, which inhibits the stress-induced increase in plasma glucocorticoids, and by mitotone, which causes adrenocortical cytolysis. It is concluded that reserpine, through the mediation of maternal glucocorticoid hormones, alters the phenotypic expression of these embryonic neuroblasts.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Jonakait, G M -- Bohn, M C -- Black, I B -- HD 12108/HD/NICHD NIH HHS/ -- NS 06400/NS/NINDS NIH HHS/ -- NS 10259/NS/NINDS NIH HHS/ -- New York, N.Y. -- Science. 1980 Oct 31;210(4469):551-3.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/7423206" target="_blank"〉PubMed〈/a〉
    Keywords: Animals ; Catecholamines/metabolism ; Female ; Hydrocortisone/*pharmacology ; Intestines/*embryology/innervation ; Maternal-Fetal Exchange ; Pregnancy ; Pregnancy, Animal/*drug effects ; Rats ; Reserpine/*pharmacology ; Sympathetic Nervous System/*embryology
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  • 73
    Publication Date: 1980-06-27
    Description: Gas deposition rates in the swim bladders of postmetamorphic (silver) Anguilla rostrata eels are about five times greater than those of premetamorphic (yellow) individuals. This extends the maximum depth at which silver eels can maintain swim bladder volume and prepares them for their spawning migration to the Sargasso Sea.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Kleckner, R C -- New York, N.Y. -- Science. 1980 Jun 27;208(4451):1481-2.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/7384792" target="_blank"〉PubMed〈/a〉
    Keywords: Acclimatization ; Air Sacs/*physiology ; Anguilla/*physiology ; Animals ; Species Specificity
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  • 74
    Publication Date: 1980-03-21
    Description: Differential interference microscopy and time-lapse cinematography were used to determine unequivocally the origin of cushion tissue cells migrating in situ in the atrioventricular region of the embryonic chick heart. These studies have verified the presumed endocardial origin of cushion tissue mesenchyme.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Kinsella, M G -- Fitzharris, T P -- New York, N.Y. -- Science. 1980 Mar 21;207(4437):1359-60.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/7355294" target="_blank"〉PubMed〈/a〉
    Keywords: Animals ; Cell Membrane/physiology ; Cell Movement ; Chick Embryo ; Endocardium/cytology/embryology ; Extracellular Space/cytology ; Heart/*embryology ; Heart Valves/embryology ; Mesoderm/cytology ; Methods
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  • 75
    Publication Date: 1980-08-29
    Description: In kidney proximal tubules of male mice the mitochondria are larger and more electron-lucent, autophagic vacuoles and lysosomes (predominantly myeloid bodies) more numerous and voluminous, and exocytosed intraluminal myeloid bodies more common than in females. Males also have higher kidney activities of mitochondrial cytochrome c oxidase and lysosomal hydrolases, and excrete larger quantities of hydrolases and protein in the urine. Orchiectomy evokes the feminine pattern whereas testosterone administration induces the male pattern. Endogenous testosterone modulates mitochondrial structure and function and enhances the activity of the lysosomal-vacuolar system in proximal tubule cells.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Koenig, H -- Goldstone, A -- Blume, G -- Lu, C Y -- New York, N.Y. -- Science. 1980 Aug 29;209(4460):1023-6.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/7403864" target="_blank"〉PubMed〈/a〉
    Keywords: Animals ; Castration ; Enzymes/urine ; Female ; Kidney/drug effects ; Kidney Tubules, Proximal/*ultrastructure ; Lysosomes/drug effects/enzymology ; Male ; Mice ; Mitochondria/drug effects/enzymology ; Organ Size/drug effects ; Sex Differentiation/*drug effects ; Testosterone/*pharmacology
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  • 76
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    American Association for the Advancement of Science (AAAS)
    Publication Date: 1980-02-29
    Description: Intraocular grafts of chick epithelium combined with mouse molar mesenchyme produced a variety of dental structures including perfectly formed crowns with differentiated ameloblasts depositing enamel matrix. The results suggest that the loss of teeth in Aves did not result from a loss of genetic coding for enamel synthesis in the oral epithelium but from an alteration in the tissue interactions requisite for odontogenesis.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Kollar, E J -- Fisher, C -- New York, N.Y. -- Science. 1980 Feb 29;207(4434):993-5.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/7352302" target="_blank"〉PubMed〈/a〉
    Keywords: *Amelogenesis ; Animals ; Chick Embryo/*cytology ; Culture Techniques ; Dental Enamel Proteins/*biosynthesis/genetics ; Embryonic Induction ; Epithelial Cells ; Genes ; Mandible/cytology ; Mesoderm/cytology ; Mice ; *Odontogenesis
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  • 77
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    American Association for the Advancement of Science (AAAS)
    Publication Date: 1980-01-25
    Description: 〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Kolata, G B -- New York, N.Y. -- Science. 1980 Jan 25;207(4429):392-3.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/7350671" target="_blank"〉PubMed〈/a〉
    Keywords: Animals ; Biological Evolution ; *Genes ; Globins/genetics ; Histones/genetics ; Insulin/genetics ; Nucleic Acid Precursors/*genetics ; Transcription, Genetic
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  • 78
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    American Association for the Advancement of Science (AAAS)
    Publication Date: 1980-04-04
    Description: A spontaneous B cell leukemia (BCL1) grew progressively in normal BALB/c mice after injection of tumor cells but did not grow in splenectomized recipients. Despite the absence of progressive tumor growth, residual tumor cells with malignant potential were found in the peripheral blood of the splenectomized animals. Splenectomy performed after injection of tumor cells but before the development of marked leukocytosis also prevented progressive tumor growth and death of the host. Thus the spleen appears to be necessary for progressive proliferation of this lymphocytic leukemia early after passage in vivo.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Kotzin, B L -- Strober, S -- New York, N.Y. -- Science. 1980 Apr 4;208(4439):59-61.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/6965803" target="_blank"〉PubMed〈/a〉
    Keywords: Animals ; B-Lymphocytes/*pathology ; Disease Models, Animal ; Female ; Leukemia, Experimental/etiology/physiopathology ; Leukemia, Lymphoid/*etiology/physiopathology ; Mice ; Mice, Inbred BALB C ; Spleen/*physiology ; Splenectomy
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  • 79
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    American Association for the Advancement of Science (AAAS)
    Publication Date: 1980-02-15
    Description: The compound eye of the grasshopper Phlaeoba has alternating bands that appear clear or brown. Electroretinograms recorded from the individual bands have different action spectra: The spectrum of the clear band peaks at 525 nanometers and that of the brown band at 545 nanometers. Spectrally selective whole-eye adaptation with light of eight long of short wavelength yields identical action spectra. This evidence suggests that this eye has only one visual pigment, whose spectrum is altered in the brown bands by a screening pigment. In behavioral tests of spontaneous choices between stimuli that appear green to the normal human and those that appear red, the green stimuli are preferred even when the relative intensity is varied by 0.9 log units around the equal-brightness level (determined by the electroretinogram). When some red light is mixed with the green light, the preference for the mixture is less than for the green light alone, even though the mixture is more intense. True color vision therefore seems to exist. Painting the bands shows that behavioral color vision requires the presence of both types. These data suggest that Phlaeoba has true color vision mediated by one visual pigment and suitable optical filters.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Kong, K L -- Fung, Y M -- Wasserman, G S -- New York, N.Y. -- Science. 1980 Feb 15;207(4432):783-6.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/7352289" target="_blank"〉PubMed〈/a〉
    Keywords: Animals ; Behavior, Animal/physiology ; Color Perception/*physiology ; Electroretinography ; Filtration ; Grasshoppers/*physiology ; Retinaldehyde/*physiology ; Vitamin A/*analogs & derivatives
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  • 80
    Publication Date: 1980-11-14
    Description: The organum vasculosum of the lamina terminalis has been implicated as the site of receptors mediating central responses of angiotensin II. Up to now, this had been based on indirect evidence, but direct visualization of angiotensin II at its site of action has now been achieved by the use of a biologically active fluorescent angiotensin II agonist. The ventricular surface of the organum vasculosum lamina terminalis showed intense fluorescence, which was virtually eliminated by an excess of unlabeled angiotensin II.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Landas, S -- Phillips, M I -- Stamler, J F -- Raizada, M K -- AM25295/AM/NIADDK NIH HHS/ -- HL14388/HL/NHLBI NIH HHS/ -- New York, N.Y. -- Science. 1980 Nov 14;210(4471):791-3.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/6254147" target="_blank"〉PubMed〈/a〉
    Keywords: Angiotensin II/*metabolism/physiology ; Animals ; Cerebral Ventricles/*metabolism ; Drinking Behavior/physiology ; Male ; Microscopy, Fluorescence ; Rats ; Receptors, Angiotensin/*metabolism ; Receptors, Cell Surface/*metabolism
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  • 81
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    American Association for the Advancement of Science (AAAS)
    Publication Date: 1980-07-11
    Description: The survival of isolated rat islets transplanted into diabetic mice was prolonged markedly by maintaining the rat islets in vitro at 24 degrees C for 7 days before transplantation and administering to the recipients a single injection of antiserum to mouse and rat lymphocytes shortly before transplantation.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Lacy, P E -- Davie, J M -- Finke, E H -- New York, N.Y. -- Science. 1980 Jul 11;209(4453):283-5.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/6770465" target="_blank"〉PubMed〈/a〉
    Keywords: Animals ; Blood Glucose/analysis ; Cell Survival ; Cells, Cultured ; Diabetes Mellitus, Experimental/*therapy ; *Immunosuppression ; *Islets of Langerhans Transplantation ; Lymphocytes/immunology ; Male ; Mice ; Mice, Inbred BALB C ; Rats ; Transplantation, Heterologous ; Transplantation, Isogeneic
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  • 82
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    American Association for the Advancement of Science (AAAS)
    Publication Date: 1980-03-14
    Description: The protozoan parasite Babesia bovis, a causative agent of bovine babesiosis, has been continuously cultivated in a settled layer of bovine erythrocytes. Lowered oxygen tension within the layer of host erythrocytes results in a darkening of infected cultures and provides a rapid means of evaluating parasite growth. Deprivation of carbon dioxide causes the merozoites to accumulate in the medium rather than involving new erythrocytes. When separated from the culture, these extraerythrocytic parasites retain their infectivity. Parasites produced in vitro are morphologically identical to parasites from the blood of infected cattle and are susceptible to antibabesial drugs.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Levy, M G -- Ristic, M -- New York, N.Y. -- Science. 1980 Mar 14;207(4436):1218-20.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/7355284" target="_blank"〉PubMed〈/a〉
    Keywords: Animals ; Babesia/*growth & development ; Cattle ; *Cells, Cultured ; Culture Media ; Erythrocytes/cytology/*parasitology
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  • 83
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    American Association for the Advancement of Science (AAAS)
    Publication Date: 1980-11-21
    Description: Single implantation of microencapsulated islets into rats with streptozotocin-induced diabetes corrected the diabetic state for 2 to 3 weeks. The microencapsulated islets remained morphologically and functionally intact throughout long-term culture studies lasting over 15 weeks.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Lim, F -- Sun, A M -- New York, N.Y. -- Science. 1980 Nov 21;210(4472):908-10.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/6776628" target="_blank"〉PubMed〈/a〉
    Keywords: Alginates/*therapeutic use ; Animals ; Cell Survival ; Diabetes Mellitus, Experimental/*therapy ; *Islets of Langerhans Transplantation ; Permeability ; Rats ; Transplantation, Homologous
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  • 84
    Publication Date: 1980-08-15
    Description: The antihistaminic over-the-counter drug methapyrilene hydrochloride, mixed with food at a concentration of 0.1 percent, was administered to 50 male and 50 female Fischer rats. A second group of 50 male and 50 female rats was given the same treatment together with 0.2 percent of sodium nitrite added to the food. Almost all of the rats in both groups developed liver neoplasms, mainly hepatocellular carcinomas and cholangiocarcinomas. The first rat died with a liver neoplasm at the 43rd week. Over 50 percent of the rats in both groups had metastases from the carcinomas of the liver to distant organs. Control rats treated with nitrite only, or untreated, did not develop liver neoplasms. There was no discernible effect of nitrite on the carcinogenicity of methapyrilene hydrochloride.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Lijinsky, W -- Reuber, M D -- Blackwell, B N -- New York, N.Y. -- Science. 1980 Aug 15;209(4458):817-9.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/7403848" target="_blank"〉PubMed〈/a〉
    Keywords: Aminopyridines/*toxicity ; Animals ; *Carcinogens ; Drug Interactions ; Female ; Liver Neoplasms, Experimental/*chemically induced/pathology ; Male ; Methapyrilene/*toxicity ; Neoplasm Metastasis ; Nitrites ; Rats
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  • 85
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    American Association for the Advancement of Science (AAAS)
    Publication Date: 1980-08-29
    Description: Extracts from several different photocopies were mutagenic in the Ames Salmonella assay. The mutagenic behavior was similar for extracts from copies and corresponding toners indicating that toners are directly responsible for the mutagenicity. The mutagenicity is caused by at least two classes of compounds which may be present either alone or in combination in any toner.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Lofroth, G -- Hefner, E -- Alfheim, I -- Mooller, M -- New York, N.Y. -- Science. 1980 Aug 29;209(4460):1037-9.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/6996094" target="_blank"〉PubMed〈/a〉
    Keywords: Animals ; Biotransformation ; Carbon ; *Copying Processes ; Drug Evaluation, Preclinical/methods ; Microsomes, Liver/metabolism ; *Mutagens ; Photography ; Pyrenes/adverse effects ; Rats ; Salmonella typhimurium/drug effects
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  • 86
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    American Association for the Advancement of Science (AAAS)
    Publication Date: 1980-06-13
    Description: Sympathetic axons, normally innervating the extracerebral vasculature, sprout into denervated regions of the hippocampal formation after lesions of the medial septal nucleus or fimbria in adult female rats. Similar lesions in adult males also elicit the sympathetic ingrowth; however, the number of anomalous axons is greatly reduced and their distribution is altered. In adult males the sympathetic axons do not send out collaterals within the stratum oriens of region CA3 or the molecular layer or deep hilar regions of the area dentata, as they do in adult females. Lesions in juveniles of both sexes result in more vigorous sprouting than in their adult counterparts. In the young males the anomalous axons are distributed more extensively into the dentate molecular layer; in the young females the axons merely send out more collaterals within the same regions as in the adults. This sexually dimorphic response to central nervous system damage suggests either that the sprouting is affected by the hormonal environment of the mature hippocampal system or that this brain region, like the hypothalamus, may express permanent morphological or physiological differences as a result of exposure to sex steroids during development.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Loy, R -- Milner, T A -- New York, N.Y. -- Science. 1980 Jun 13;208(4449):1282-4.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/7375941" target="_blank"〉PubMed〈/a〉
    Keywords: Aging ; Animals ; Axons/growth & development ; Denervation ; Female ; Gonadal Steroid Hormones/physiology ; Hippocampus/*cytology ; Male ; Neural Pathways/cytology ; Rats ; *Sex ; Sympathetic Nervous System/*cytology/growth & development
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  • 87
    Publication Date: 1980-10-10
    Description: A transient increase in ornithine decarboxylase activity and polyamine biosynthesis occurs in the intestinal mucosa of the newborn rat in the third week after birth. During this period, there is a rapid conversion of the mucosa from a fetal to a mature adult status. A similar increase in ornithine decarboxylase activity also accompanies the rapid recovery of the mucosa 1 week after an injury is induced by chemotherapy in adult rats. In vivo, alpha-difluoromethyl ornithine, a highly selective, enzyme-activated, irreversible inhibitor, suppresses these increases in mucosal ornithine decarboxylase and delays both intestinal mucosal maturation and recovery from injury. Thus increased ornithine decarboxylase activity, with the resultant increase in polyamine content, may play an essential role in intestinal mucosal maturation and regeneration in the rat.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Lux, G D -- Marton, L J -- Baylin, S B -- 5-R01-18404/PHS HHS/ -- 5-T32-AM-07192-03/AM/NIADDK NIH HHS/ -- P50-HL-19157-01/HL/NHLBI NIH HHS/ -- etc. -- New York, N.Y. -- Science. 1980 Oct 10;210(4466):195-8.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/6774420" target="_blank"〉PubMed〈/a〉
    Keywords: Amine Oxidase (Copper-Containing)/metabolism ; Animals ; Carboxy-Lyases/*physiology ; Cell Differentiation ; Cell Division ; Cytarabine/pharmacology ; Intestinal Mucosa/cytology/drug effects/*physiology ; Ornithine Decarboxylase/*physiology ; Ornithine Decarboxylase Inhibitors ; Putrescine/metabolism ; Rats ; Spermidine/metabolism ; Wound Healing
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  • 88
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    American Association for the Advancement of Science (AAAS)
    Publication Date: 1980-01-11
    Description: 〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Macklin, A W -- Welch, R M -- New York, N.Y. -- Science. 1980 Jan 11;207(4427):129-30, 132.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/7350647" target="_blank"〉PubMed〈/a〉
    Keywords: Aminopyrine/adverse effects/toxicity ; Animals ; Humans ; Mice ; Mutagens ; Phenacetin/administration & dosage/*adverse effects/toxicity ; Rats
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  • 89
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    American Association for the Advancement of Science (AAAS)
    Publication Date: 1980-09-19
    Description: Two types of immature B cells, namely fetal liver hybridomas and the leukemic cell line 70Z/3, both of which have cytoplasmic mu chains but no light chains, were examined for DNA rearrangements of their light chain and heavy chain immunoglobulin genes. In the fetal liver hybridomas, which were constructed from fetal liver cells and a tumor cell, no light chain gene rearrangement was observed, whereas in the 70Z/3 cell line a kappa light chain rearrangement probably occurred. The results suggest that, although the lack of light chain synthesis can be due to a lack of gene rearrangement, there may also be transcriptional regulation, which may also be important for the expression of light chain immunoglobulins in immature B cells.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Maki, R -- Kearney, J -- Paige, C -- Tonegawa, S -- New York, N.Y. -- Science. 1980 Sep 19;209(4463):1366-9.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/6774416" target="_blank"〉PubMed〈/a〉
    Keywords: Animals ; B-Lymphocytes/*immunology ; Genes ; Hybrid Cells/immunology ; Immunoglobulin Constant Regions/genetics ; Immunoglobulin Heavy Chains/*genetics ; Immunoglobulin Light Chains/*genetics ; Immunoglobulin Variable Region/genetics ; Immunoglobulin kappa-Chains/*genetics ; Immunoglobulin mu-Chains/*genetics ; Leukemia, Experimental/*immunology ; Liver/*embryology ; Mice ; Recombination, Genetic ; Transcription, Genetic
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  • 90
    Publication Date: 1980-09-19
    Description: A single DNA fragment containing both mu and delta immunoglobulin heavy chain genes has been cloned from normal BALB/c mouse liver DNA with a new lambda phage vector Charon 28. The physical distance between the membrane terminal exon of mu and the first domain of delta is 2466 base pairs, with delta on the 3' side of mu. A single transcript could contain a variable region and both mu and delta constant regions. The dual expression of immunoglobulins M and D on spleen B cells may be due to alternate splicing of this transcript.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Liu, C P -- Tucker, P W -- Mushinski, J F -- Blattner, F R -- New York, N.Y. -- Science. 1980 Sep 19;209(4463):1348-53.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/6774414" target="_blank"〉PubMed〈/a〉
    Keywords: Animals ; B-Lymphocytes/immunology ; Chromosome Deletion ; *Genes ; Immunoglobulin Constant Regions/genetics ; Immunoglobulin Heavy Chains/*genetics ; Immunoglobulin delta-Chains/*genetics ; Immunoglobulin mu-Chains/*genetics ; Liver/physiology ; Membrane Proteins/genetics ; Mice ; Myeloma Proteins/genetics ; Plasmids ; RNA, Messenger/genetics ; Recombination, Genetic
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  • 91
    Publication Date: 1980-03-07
    Description: Nuclear receptors for both estradiol and progesterone were present in twofold higher concentrations in implantation sites than in nonimplantation regions of the endometrium of 6-day pregnant rats. Decidualization in the absence of an embryo was not accompanied by a similar increase in the concentration of nuclear receptors. Moreover, this difference in receptor distribution between the implantation and nonimplantation areas persisted when a major part of the maternal supply of sex steroids was suppressed by ovariectomy on day 5 of pregnancy. These results support the hypothesis that steroids originating from the embryo affect the endometrial implantation site.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Logeat, F -- Sartor, P -- Hai, M T -- Milgrom, E -- New York, N.Y. -- Science. 1980 Mar 7;207(4435):1083-5.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/7355273" target="_blank"〉PubMed〈/a〉
    Keywords: Animals ; Blastocyst/*metabolism ; Castration ; Cell Nucleus/metabolism ; Decidua/metabolism ; Endometrium/*metabolism/ultrastructure ; Female ; Gestational Age ; Pregnancy ; Pseudopregnancy ; Rats ; Receptors, Estrogen/*metabolism ; Receptors, Progesterone/*metabolism
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  • 92
    Publication Date: 1980-02-01
    Description: A 200-fold inhibition in the titer of infectious vesicular stomatitis virus (VSV) was produced in cultures of Ly cells treated with 30 reference units of interferon per milliliter. Virus particle production, as measured by VSV particle-associated transcriptase, or nucleocapsid protein was inhibited by a maximum of tenfold. The glycoprotein and membrane protein content was reduced in VSV derived from interferon-treated cells. Thus interferon-treated cells may have produced VSV particles with low infectivity, which may be related to the reduced amount of glycoprotein incorporated into such particles. These findings resemble those reported in interferon-treated cells infected with murine leukemia viruses.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Maheshwari, R K -- Jay, F T -- Friedman, R M -- New York, N.Y. -- Science. 1980 Feb 1;207(4430):540-1.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/6243416" target="_blank"〉PubMed〈/a〉
    Keywords: Animals ; Cells, Cultured ; Defective Viruses/growth & development ; Glycoproteins/*biosynthesis ; Interferons/*pharmacology ; Membrane Proteins/*biosynthesis ; Mice ; RNA, Viral/metabolism ; Vesicular stomatitis Indiana virus/*growth & development ; Viral Proteins/*biosynthesis ; Virus Replication/*drug effects
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  • 93
    Publication Date: 1980-09-26
    Description: 〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Mardian, J K -- Paton, A E -- Bunick, G J -- Olins, D E -- GM 19334/GM/NIGMS NIH HHS/ -- GM 7438/GM/NIGMS NIH HHS/ -- New York, N.Y. -- Science. 1980 Sep 26;209(4464):1534-6.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/7433974" target="_blank"〉PubMed〈/a〉
    Keywords: Animals ; Binding Sites ; Chickens ; Chromosomal Proteins, Non-Histone/*metabolism ; Erythrocytes/ultrastructure ; Nucleosomes/*metabolism/ultrastructure ; Poly dA-dT/metabolism ; Protein Binding
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  • 94
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    American Association for the Advancement of Science (AAAS)
    Publication Date: 1980-04-18
    Description: 〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Marx, J L -- New York, N.Y. -- Science. 1980 Apr 18;208(4441):274-6.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/6102798" target="_blank"〉PubMed〈/a〉
    Keywords: Actomyosin/physiology ; Animals ; Calcium/*physiology ; Calcium-Binding Proteins/*physiology ; Calcium-Transporting ATPases/metabolism ; Calmodulin/*physiology ; Cyclic AMP/metabolism ; Humans ; Mitosis ; Muscle Contraction ; Muscle, Smooth/physiology ; NAD/metabolism ; Neurotransmitter Agents/metabolism ; Phosphoric Diester Hydrolases/metabolism ; Protein Kinases/metabolism
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  • 95
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    American Association for the Advancement of Science (AAAS)
    Publication Date: 1980-03-21
    Description: 〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Marx, J L -- New York, N.Y. -- Science. 1980 Mar 21;207(4437):1330-3.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/7355293" target="_blank"〉PubMed〈/a〉
    Keywords: *Animal Communication ; Animals ; Hominidae/*physiology ; *Language ; Sign Language
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  • 96
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    American Association for the Advancement of Science (AAAS)
    Publication Date: 1980-07-25
    Description: Intracellular recordings from voltage-clamped mouse spinal neurons in tissue culture were used to study the membrane mechanisms underlying inhibitory responses to gamma-aminobutyric acid and the (-) isomer of pentobarbital. Fluctuation analysis suggested that both substances activated ion channels in the membranes. However, the channels activated by pentobarbital remained open five times longer than those activated by gamma-aminobutyric acid.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Mathers, D A -- Barker, J L -- New York, N.Y. -- Science. 1980 Jul 25;209(4455):507-9.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/6248961" target="_blank"〉PubMed〈/a〉
    Keywords: Animals ; Cell Membrane/drug effects/physiology ; Cells, Cultured ; Ion Channels/drug effects/*physiology ; Membrane Potentials/drug effects ; Mice ; Neurons/drug effects/*physiology ; Pentobarbital/*pharmacology ; Spinal Cord/*physiology ; gamma-Aminobutyric Acid/pharmacology
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  • 97
    Publication Date: 1980-01-18
    Description: When unilamellar vesicles were administered subcutaneously in mice, the half-time for the destruction of the vesicles varied from 12 to 600 hours, depending on their composition. The vesicles tested consisted of distearoyl phosphatidylcholine, cholesterol, and certain sugar and amino-sugar derivatives of cholesterol. Vesicle with amino-sugar derivatives showed the greatest longevity and became localized with high specificity in aggregates of polymorphonuclear leukocytes. A substantial delay between the time that the vesicles broke open and the time that labels contained in the vesicles were excreted suggests that the vesicles undergo endocytosis before destruction.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Mauk, M R -- Gamble, R C -- Baldeschwieler, J D -- New York, N.Y. -- Science. 1980 Jan 18;207(4428):309-11.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/7350660" target="_blank"〉PubMed〈/a〉
    Keywords: Animals ; Cholesterol/analogs & derivatives ; Endocytosis ; Liposomes/*therapeutic use ; Lysosomes/metabolism ; Metabolic Clearance Rate ; Mice ; Neutrophils/*metabolism ; Phosphatidylcholines ; Structure-Activity Relationship
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  • 98
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    American Association for the Advancement of Science (AAAS)
    Publication Date: 1980-06-06
    Description: Most models of the saccadic eye movement system imply that saccades are programmed for a certain distance and direction. Electrical stimulation of the brain was used to move the eyes of monkeys just before saccades to visual targets. Despite the stimulation-induced perturbation, saccades brought gaze to the target locations. This compensation indicates that saccades are coded to direct the eyes to a certain position in the orbit (or in space).〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Mays, L E -- Sparks, D L -- New York, N.Y. -- Science. 1980 Jun 6;208(4448):1163-5.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/6769161" target="_blank"〉PubMed〈/a〉
    Keywords: Animals ; Electric Stimulation ; *Eye Movements ; Feedback ; Haplorhini ; Macaca ; Orientation/physiology ; Retina/*physiology ; *Saccades ; Space Perception/*physiology ; Superior Colliculi/physiology
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  • 99
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    American Association for the Advancement of Science (AAAS)
    Publication Date: 1980-03-14
    Description: Mebendazole was highly effective against the helminth parasite Trichinella spiralis in mice subjected to a 3-day course of treatment during the invasive and encystment phases of experimental trichinellosis. When treatment began either 2 or 4 weeks after the mice were inoculated with parasites, the number of larvae developing in the host musculature was greatly reduced by twice-daily oral administration of 3.125, 6.25, or 12.5 milligrams of mebendazole per kilogram of body weight.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉McCracken, R O -- Taylor, D D -- New York, N.Y. -- Science. 1980 Mar 14;207(4436):1220-2.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/7355285" target="_blank"〉PubMed〈/a〉
    Keywords: Administration, Oral ; Animals ; Benzimidazoles/*therapeutic use ; Disease Models, Animal ; Dose-Response Relationship, Drug ; Larva ; Male ; Mebendazole/administration & dosage/*therapeutic use ; Mice ; Muscles/parasitology ; Trichinella/drug effects ; Trichinellosis/*drug therapy
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  • 100
    Publication Date: 1980-01-18
    Description: Studies of the effect of the dopamine agonist apomorphine on local cerebral glucose utilization by means of the carbon-14-labeled deoxyglucose method demonstrate a dose-dependent metabolic activation in the superficial layer of the superior colliculus in the rat. Apomorphine stimulated glucose utilization in a number of other cerebral structures, but only the effect in the superficial layer of the superior colliculus depended on an intact retinal input. This effect was present with the animal in the light or in the dark, but was abolished by enucleation, which left the effects in other cerebral structures unimpaired. Activation of the superificial layer of the superior colliculus appears, therefore, to be secondary to an action of apomorphine on dopaminergic systems within the retina.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉McCulloch, J -- Savaki, H E -- McCulloch, M C -- Sokoloff, L -- New York, N.Y. -- Science. 1980 Jan 18;207(4428):313-5.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/7350662" target="_blank"〉PubMed〈/a〉
    Keywords: Animals ; Apomorphine/*pharmacology ; Dark Adaptation ; Dopamine/*physiology ; Functional Laterality ; Geniculate Bodies/metabolism ; Glucose/*metabolism ; Rats ; Retina/*physiology ; Superior Colliculi/drug effects/*metabolism ; Visual Cortex/metabolism ; Visual Pathways/physiology ; Visual Perception/*physiology
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    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
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