Microencapsulated islets as bioartificial endocrine pancreas

F Lim; A M Sun

doi:10.1126/science.6776628

Microencapsulated islets as bioartificial endocrine pancreas

Science. 1980 Nov 21;210(4472):908-10. doi: 10.1126/science.6776628.

Authors

F Lim, A M Sun

PMID: 6776628
DOI: 10.1126/science.6776628

Abstract

Single implantation of microencapsulated islets into rats with streptozotocin-induced diabetes corrected the diabetic state for 2 to 3 weeks. The microencapsulated islets remained morphologically and functionally intact throughout long-term culture studies lasting over 15 weeks.

Publication types

Research Support, Non-U.S. Gov't

MeSH terms

Alginates / therapeutic use*
Animals
Cell Survival
Diabetes Mellitus, Experimental / therapy*
Islets of Langerhans Transplantation*
Permeability
Rats
Transplantation, Homologous

Substances

Alginates