Abstract
The survival of isolated rat islets transplanted into diabetic mice was prolonged markedly by maintaining the rat islets in vitro at 24 degrees C for 7 days before transplantation and administering to the recipients a single injection of antiserum to mouse and rat lymphocytes shortly before transplantation.
Publication types
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Research Support, U.S. Gov't, P.H.S.
MeSH terms
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Animals
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Blood Glucose / analysis
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Cell Survival
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Cells, Cultured
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Diabetes Mellitus, Experimental / therapy*
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Immunosuppression Therapy*
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Islets of Langerhans Transplantation*
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Lymphocytes / immunology
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Male
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Mice
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Mice, Inbred BALB C
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Rats
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Transplantation, Heterologous
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Transplantation, Isogeneic