Publication Date:
1980-04-04
Description:
Lysyl oxidase activity was found in the isthmus (the membrane-forming region) of the hen's oviduct in a copper-rich region proximal to the shell gland. Desmosine and isodesmosine, cross-linking compounds associated with mature elastin, were found in hydrolysates of the shell membrane, confirming the necessity for lysyl oxidase in its biosynthesis. Shell membranes from hens fed a copper-deficient diet or a diet supplemented with beta-aminopropionitrile had a reduced content of desmosine and isodesmosine.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Harris, E D -- Blount, J E -- Leach, R M Jr -- New York, N.Y. -- Science. 1980 Apr 4;208(4439):55-6.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/6102412" target="_blank"〉PubMed〈/a〉
Keywords:
Amino Acid Oxidoreductases/*metabolism
;
Animals
;
Chickens/*metabolism
;
Copper/metabolism
;
Cross-Linking Reagents
;
Desmosine/analysis
;
*Egg Shell
;
Isodesmosine/analysis
;
Oviducts/*enzymology
;
Protein-Lysine 6-Oxidase/*metabolism
Print ISSN:
0036-8075
Electronic ISSN:
1095-9203
Topics:
Biology
,
Chemistry and Pharmacology
,
Computer Science
,
Medicine
,
Natural Sciences in General
,
Physics