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  • General Chemistry  (2,207)
  • Organic Chemistry  (2,076)
  • Polymer and Materials Science  (2,009)
  • Aircraft Propulsion and Power
  • Seismology
  • 2005-2009  (610)
  • 1950-1954  (6,379)
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  • 1
    Publication Date: 2017-04-04
    Description: The West side of lake of Garda, in Northern Italy, was struck by a ML=5.2 earthquake on November 24, 2004. The felt area is rather large (from Venice to Milan) and the damaged area consists of 66 municipalities, with a number of homeless of about 2200 and estimated direct damages of 215 millions of euros. Most of the damaged structures are old masonry buildings and churches, while there were almost no damage to reinforced concrete structures. The observed distribution of macroseismic intensity shows a strong azimuthal dependence, with high intensity level in a 10x10 km2 area located SW to the epicentre and rather large dispersion of values (ranging from V to VII-VIII) in the first 10 km epicentral distance. Taking into account the vulnerability level of the damaged structures and the features of the geological formations, we tried to explain the observed damage distribution in terms of finite fault properties of the source, despite the moderate magnitude of the event. Thus we hypothesised a fault geometry from seismotectonic considerations and we simulated the event by a high frequency simulation technique (Deterministic Stochastic Method, DSM). The synthetic ground motion parameters were converted into intensity values by empirical relationships and local geological conditions were considered to explain some discrepancies between simulated and observed intensities. It was possible to adequately reproduce both the observed distribution of macroseismic intensity and the ground motion recorded by an accelerometric station located at about 13 km epicentral distance.
    Description: Unpublished
    Description: Geneva, Switzerland
    Description: open
    Keywords: Damage ; Seismology ; 04. Solid Earth::04.06. Seismology::04.06.04. Ground motion
    Repository Name: Istituto Nazionale di Geofisica e Vulcanologia (INGV)
    Type: Conference paper
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  • 2
    Publication Date: 2017-04-04
    Description: To mark the centennial anniversary of the 1908 earthquake that shook Messina, Italy, the Istituto Nazionale di Geofisica e Vulcanologia (INGV) began the “Messina 1908–2008” research project. The aim is to clarify the extension deformation processes that occur in the Strait of Messina and to understand relationships between subduction and crustal deformation there by merging existing data and studies, and by collecting new and more detailed seismological, geodetic, historical, and satellite observations.
    Description: INGV
    Description: Published
    Description: 225–226
    Description: 3.3. Geodinamica e struttura dell'interno della Terra
    Description: N/A or not JCR
    Description: reserved
    Keywords: Seismology ; geodesy ; 01. Atmosphere::01.03. Magnetosphere::01.03.04. Structure and dynamics
    Repository Name: Istituto Nazionale di Geofisica e Vulcanologia (INGV)
    Type: article
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  • 3
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    Earthquake Engineering Research Institute
    Publication Date: 2017-04-04
    Description: Two earthquakes (both having Mw 5.7) struck the eastern portion of Molise on October 31 and November 1, 2002. Both caused severe damage over a 2000 km2 region straddling Molise and Puglia. The two larger shocks and the rather unusual aftershock sequence surprised most Italian seismologists and tectonicists. Although Italy has a good record of historical and instrumental seismicity and its main seismogenic trends are quite established, the epicentral location, depth and kinematics of this earthquake sequence were largely unexpected. In fact, the 2002 Molise earthquakes shed light on a previously unsuspected style of seismogenic faulting in this region. From the seismotectonic perspective, much of the significance of the two quakes arises from the possibility that this style of faulting might be shared by several much larger quakes that took place on the Adriatic side of the southern Apennines. In the first part of this paper we briefly describe the main seismological characteristics of the sequence. These were largely derived from the analysis of data supplied by permanent networks and from a preliminary analysis of data recorded by a portable network deployed a few hours after the first shock. In the second part of the paper we discuss the seismotectonic characteristics of the sequence in the framework of Italian tectonics and the implications for future earthquakes in the same region.
    Description: Published
    Description: S23-S37
    Description: reserved
    Keywords: Earthquake ; Molise 2002 ; Seismology ; Tectonic ; 04. Solid Earth::04.06. Seismology::04.06.04. Ground motion ; 04. Solid Earth::04.07. Tectonophysics::04.07.07. Tectonics
    Repository Name: Istituto Nazionale di Geofisica e Vulcanologia (INGV)
    Type: article
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  • 4
    Publication Date: 2017-04-04
    Description: A field survey performed during the 1997 Umbria-Marche earthquake sequence led us to recognize ground and pavement ruptures associated with the three largest shocks (M〉= 5.7). The ruptures are concentrated in narrow bands that, in part, are on and near previously mapped high-angle normal fauts. The geometry of the ground deformation is consistent with the NE-trending extension indicated by CMT focal solutions of the mainshocks. The distribution of aftershocks suggests that the three mainshocks occurred on ~40 degree SW-dipping normal faults. Geological investigations, modelling of expected coseismic elevation changes, and seismic data, suggest that the surface deformation is not the direct result of primary rupture of faults at depth.
    Description: Published
    Description: 895-898
    Description: reserved
    Keywords: Structural geology ; Fractures and faults ; Seismology ; Seismicity and seismotectonics ; Europe ; 04. Solid Earth::04.04. Geology::04.04.01. Earthquake geology and paleoseismology
    Repository Name: Istituto Nazionale di Geofisica e Vulcanologia (INGV)
    Type: article
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  • 5
    Publication Date: 2017-04-04
    Description: A correlation has been recently found between large earthquakes and the succeeding largest 9 explosive eruptions of the last century, which has been interpreted as a product of co- and post-seismic stress diffusion. Here, we check the statistical significance of the proposed coupling by using a larger dataset, and investigate the reliability of the causality hypothesis. We find that the volcanoes with VEI ≥ 4 eruptions underwent, in the few decades before the volcanic event, higher seismic stress perturbations due to large earthquakes compared to other volcanic areas. The correlation is statistically significant and it is not explained by a spatio-temporal clustering of eruptions and earthquakes due to tectonic pulses. This implies that the large earthquakes indeed triggered the eruptions.
    Description: Gruppo Nazionale di Vulcanologia and e-Ruption projects
    Description: Published
    Description: reserved
    Keywords: Volcanology ; Eruption mechanisms ; Seismology ; Volcano seismology ; Tectonophysics ; Stresses - general ; 05. General::05.01. Computational geophysics::05.01.04. Statistical analysis
    Repository Name: Istituto Nazionale di Geofisica e Vulcanologia (INGV)
    Type: article
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  • 6
    Publication Date: 2017-04-03
    Description: We describe and discuss some activities of our working group to disseminate scientific issues concerning seismology to the students of the Region Liguria.
    Description: Published
    Description: Rimini, Italy
    Description: 5.9. Formazione e informazione
    Description: open
    Keywords: Education ; Seismology ; Preparedness ; 05. General::05.03. Educational, History of Science, Public Issues::05.03.99. General or miscellaneous
    Repository Name: Istituto Nazionale di Geofisica e Vulcanologia (INGV)
    Type: Abstract
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  • 7
    Publication Date: 2019-11-04
    Description: We investigate conceptually, analytically, and numerically the biases in the estimation of the b-value of the Gutenberg-Richter law and of its uncertainty made through the least squares technique. The biases are introduced by the cumulation operation for the cumulative form of the Gutenberg-Richter law, by the logarithmic transformation, and by the measurement errors on the magnitude. We find that the least squares technique, applied to the cumulative and binned form of the Gutenberg-Richter law, produces strong bias in the b-value and its uncertainty, whose amplitudes depend on the size of the sample. Furthermore, the logarithmic transformation produces two different endemic bends in the Log(N) versus M curve. This means that this plot might produce fake significant departures from the Gutenberg-Richter law. The effect of the measurement errors is negligible compared to those of cumulation operation and logarithmic transformation. The results obtained show that the least squares technique should never be used to determine the slope of the Gutenberg-Richter law and its uncertainty.
    Description: Submitted
    Description: JCR Journal
    Description: open
    Keywords: b-value ; Seismology ; Least Squares technique ; Synthetic-earthquake catalogs ; 05. General::05.01. Computational geophysics::05.01.04. Statistical analysis
    Repository Name: Istituto Nazionale di Geofisica e Vulcanologia (INGV)
    Type: article
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  • 8
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    Massachusetts Institute of Technology and Woods Hole Oceanographic Institution
    Publication Date: 2022-05-25
    Description: Submitted in partial fulfillment of the requirements for the degree of Doctor of Philosophy at the Massachusetts Institute of Technology and the Woods Hole Oceanographic Institution February 2007
    Description: Oceanic spreading centers are sites of magmatic, tectonic, and hydrothermal processes. In this thesis I present experimental and seismological constraints on the evolution of these complex regions of focused crustal accretion and extension. Experimental results from drained, triaxial deformation experiments on partially molten olivine reveal that melt extraction rates are linearly dependent on effective mean stress when the effective mean stress is low and non-linearly dependent on effective mean stress when it is high. Microearthquakes recorded above an inferred magma reservoir along the TAG segment of the Mid-Atlantic Ridge delineate for the first time the arcuate, subsurface structure of a long-lived, active detachment fault. This fault penetrates the entire oceanic crust and forms the high-permeability pathway necessary to sustain long-lived, high-temperature hydrothermal venting in this region. Long-lived detachment faulting exhumes lower crustal and mantle rocks. Residual stresses generated by thermal expansion anisotropy and mismatch in the uplifting, cooling rock trigger grain boundary microfractures if stress intensities at the tips of naturally occurring flaws exceed a critical stress intensity factor. Experimental results coupled with geomechanical models indicate that pervasive grain boundary cracking occurs in mantle peridotite when it is uplifted to within 4 km of the seafloor. Whereas faults provide the high-permeability pathways necessary to sustain high-temperature fluid circulation, grain boundary cracks form the interconnected network required for pervasive alteration of the oceanic lithosphere. This thesis provides fundamental constraints on the rheology, evolution, and alteration of the lithosphere at oceanic spreading centers.
    Description: Research was funded by a MIT Presidential Fellowship and NSF grants OCE-0095936, OCE-9907224, OCE-0137329, OCE-6892222, and OCE-6897400.
    Keywords: Seismology ; Sea-floor spreading
    Repository Name: Woods Hole Open Access Server
    Type: Thesis
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  • 9
    Publication Date: 2022-05-25
    Description: Author Posting. © American Geophysical Union, 2003. It is posted here by permission of American Geophysical Union for personal use, not for redistribution. The definitive version was published in Geochemistry Geophysics Geosystems 4 (2003): 1092, doi:10.1029/2002GC000485.
    Description: The primary goal of the Ocean Seismic Network Pilot Experiment (OSNPE) was to learn how to make high quality broadband seismic measurements on the ocean bottom in preparation for a permanent ocean seismic network. The experiment also had implications for the development of a capability for temporary (e.g., 1 year duration) seismic experiments on the ocean floor. Equipment for installing, operating and monitoring borehole observatories in the deep sea was also tested including a lead-in package, a logging probe, a wire line packer and a control vehicle. The control vehicle was used in three modes during the experiment: for observation of seafloor features and equipment, for equipment launch and recovery, and for power supply and telemetry between ocean bottom units and the ship. The OSNPE which was completed in June 1998 acquired almost four months of continuous data and it demonstrated clearly that a combination of shallow buried and borehole broadband sensors could provide comparable quality data to broadband seismic installations on islands and continents. Burial in soft mud appears to be adequate at frequencies below the microseism peak. Although the borehole sensor was subject to installation noise at low frequencies (0.6 to 50 mHz), analysis of the OSNPE data provides new insights into our understanding of ocean bottom ambient noise. The OSNPE results clearly demonstrate the importance of sediment borne shear modes in ocean bottom ambient noise behavior. Ambient noise drops significantly at high frequencies for a sensor placed just at the sediment basalt interface. At frequencies above the microseism peak, there are two reasons that ocean bottom stations have been generally regarded as noisier than island or land stations: ocean bottom stations are closer to the noise source (the surface gravity waves) and most ocean bottom stations to date have been installed on low rigidity sediments where they are subject to the effects of shear wave resonances. When sensors are placed in boreholes in basement the performance of ocean bottom seismic stations approaches that of continental and island stations. A broadband borehole seismic station should be included in any real-time ocean bottom observatory.
    Description: This work was sponsored by the National Science Foundation (NSF Grant Numbers: OCE-9522114, OCE-9523541 and OCE-9819439) with additional support from Incorporated Research Institutions for Seismology (IRIS), Joint Oceanographic Institutions, Inc. (JOI Contract No: 12-94), Scripps Institution of Oceanography, a Mellon Grant from Woods Hole Oceanographic Institution, and the Earthquake Research Institute at the University of Tokyo (Visiting Professorship for RAS).
    Keywords: Ocean Seismic Network Pilot Experiment (OSNPE) ; Seismology ; Instruments and techniques ; Body wave propagation ; Surface waves and free oscillations
    Repository Name: Woods Hole Open Access Server
    Type: Article
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  • 10
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    Acoustical Society of America
    Publication Date: 2022-05-25
    Description: Author Posting. © Acoustical Society of America, 2007. This article is posted here by permission of Acoustical Society of America for personal use, not for redistribution. The definitive version was published in Journal of the Acoustical Society of America 122 (2007): 777-785, doi:10.1121/1.2751268.
    Description: A highly efficient frequency-controlled sound source based on a tunable high-Q underwater acoustic resonator is described. The required spectrum width was achieved by transmitting a linear frequency-modulated signal and simultaneously tuning the resonance frequency, keeping the sound source in resonance at the instantaneous frequency of the signal transmitted. Such sound sources have applications in ocean-acoustic tomography and deep-penetration seismic tomography. Mathematical analysis and numerical simulation show the Helmholtz resonator's ability for instant resonant frequency switching and quick adjustment of its resonant frequency to the instantaneous frequency signal. The concept of a quick frequency adjustment filter is considered. The discussion includes the simplest lumped resonant source as well as the complicated distributed system of a tunable organ pipe. A numerical model of the tunable organ pipe is shown to have a form similar to a transmission line segment. This provides a general form for the principal results, which can be applied to tunable resonators of a different physical nature. The numerical simulation shows that the “state-switched” concept also works in the high-Q tunable organ pipe, and the speed of frequency sweeping in a high-Q tunable organ pipe is analyzed. The simulation results were applied to a projector design for ocean-acoustic tomography.
    Description: The work was supported by ONR.
    Keywords: Acoustic generators ; Underwater sound ; Acoustic resonators ; Oceanographic equipment ; Seismology
    Repository Name: Woods Hole Open Access Server
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  • 11
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    Massachusetts Institute of Technology and Woods Hole Oceanographic Institution
    Publication Date: 2022-05-25
    Description: Submitted in partial fulfillment of the requirements for the degree of Doctor of Philosophy at the Massachusetts Institute of Technology and the Woods Hole Oceanographic Institution December 1997
    Description: A new tomographic technique is employed to investigate the structure and dynamics of the Pacific upper mantle. We invert band-center travel times of ScS reverberations and frequency-dependent travel times of direct S phases, upper-mantle guided waves such as SS and SSS, and the R1 and G1 surface waves for the 2D composite structure in the plane of two Pacific corridors. The frequency-dependent travel times of the turning and surface waves are measured from all three components of ground motion as phase delays relative to a radially-anisotropic, spherically-symmetric oceanic mantle model, and their 2D Fréchet kernels are constructed by a coupled-mode algorithm. The travel times of the primary ScSn and sScSn phases and their first-order reverberations from the 410 and 660 discontinuities are measured as individual phases and the 2D Fréchet kernels for these band-limited signals are calculated using the paraxial ray approximation. The model parameters include shear-speed variations throughout the mantle, perturbations to radial shear-wave anisotropy in the uppermost mantle, and the topography of the 410 and 660 discontinuities. We construct vertical tomograms through two mantle corridors: one between the Tonga subduction zone and Oahu, Hawaii, which traverses the central Pacific Ocean; and the other between the Ryukyu subduction zone and Oahu, which samples the northern Philippine Sea, the western Pacific, and the entire Hawaiian swell. Tests demonstrate that the data sets for the two corridors resolve the lateral structure in the upper mantle with a scale length of a few hundreds kilometers and greater but that the resolving power decreases rapidly in the lower mantle. The model for the Tonga-Hawaii corridor reveals several interesting features, the most significant being a regular pattern of high and low shear velocities in the upper mantle between Tonga and Hawaii. These variations, which are well resolved by the data set, have a horizontal wavelength of 1500 km, a vertical dimension of 700 km, and an amplitude of about 3%, and they show a strong positive correlation with seafloor topography and geoid-height variations along this corridor. The geoid highs correspond to a series of northwest-trending swells associated with the major hotspots of the Society, Marquesas, and Hawaiian Islands. Where these swells cross the corridor, they are underlain by high shear velocities throughout the uppermost mantle, so it is unlikely that their topography is supported by thermal buoyancy. This result is substantiated by the model from the Ryukyu-Hawaii corridor, which exhibits a prominent, fast region that extends beneath the entire Hawaiian swell. This anomaly, which resides in the uppermost 200-300 km of the mantle, is also positively correlated with the undulations of the Hawaiian-swell height. The other dominant features in the Ryukyu-Hawaii model include the high-velocity subducting slabs beneath the Ryukyu and Izu-Bonin seismic zones, which extend throughout the entire upper mantle; a very low-velocity in the uppermost 160 km of the mantle beneath the northern Philippine Sea, which is ascribed to the presence of extra water in this region; and a pronounced minimum in the amount of radial anisotropy near Hawaii, which is also seen along the Tonga-Hawaii corridor. A joint inversion of the data from the two corridors reveals the same anomaly pattern and clearly demonstrates that the swells in the Central Pacific are underlain by fast velocities. It is therefore implied that the topography of the swells in the central Pacific is supported by a chemical buoyancy mechanism which is generated by basaltic volcanism and the formation of its low-density peridotitic residuum. While the basaltic depletion mechanism can produce high shear velocities in the uppermost 200 km, it cannot explain the depth extent of the fast anomalies beneath the swells which, along Tonga-Hawaii corridor, extend well into the transition zone. It is therefore hypothesized that the central Pacific is underlain by a system of convective rolls that are confined above the 660-km discontinuity. It is likely that these rolls are predominantly oriented in the direction of plate motion (like "Richter rolls ") but the limited depth of the fast anomaly beneath the Hawaiian swell (200-300 km) suggests that their pattern is probably more complicated. Nevertheless, this convection pattern appears to be strongly correlated with the locations of the Tahitian, Marquesan, and Hawaiian hotspots, which raises interesting questions for Morgan's hypothesis that these hotspots are the surface manifestations of deep-mantle plumes.
    Description: This research was supported by the National Science Foundation under grant EAR- 9628351 and by the Defense Special Weapons Agency under grant DSW A-F49620-95-1- 0051.
    Keywords: Seismic tomography ; Seismology ; Upwelling ; Ocean waves
    Repository Name: Woods Hole Open Access Server
    Type: Thesis
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  • 12
    Publication Date: 2022-05-25
    Description: This report describes a preliminary analysis of borehole seismic data to determine VLF/Sub-bottom Seismic Noise in the Atlantic and the preliminary results of finite difference modelling for a Cape Fear environment. Noise levels were not a simple function of depth and there are indications that noise levels may depend on local geology about a given receiver position and/or on clamping. Coherency of the noise was generally poor (〈0.8) and was independent of depth. There is no evidence for distinct polarizations or directionality of the noise. The lowest determined value for ambient noise power on the vertical component was 10-4 nm2/Hz in the frequency range from 5-50 Hz. The better clamped horizontal component had comparable power values. In conclusion, although the drill ship was on the site and drill pipe was in the hole, analysis of the data for a large number of windows can provide meaningful upper bounds on the ambient noise levels in the upper crust.
    Description: Prepared for the Naval Ocean Research and Development Activity as the final report for Contract Purchase Order No. N62306-86-l4-7589
    Keywords: Ambient sounds ; Seismology
    Repository Name: Woods Hole Open Access Server
    Type: Working Paper
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  • 13
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    Massachusetts Institute of Technology and Woods Hole Oceanographic Institution
    Publication Date: 2022-05-26
    Description: Submitted in partial fulfillment of the requirements of the degree of Master of Science at the Massachusetts Institute of Technology and the Woods Hole Oceanographic Institution June 2004
    Description: Laterally extensive, well-developed clinoforms have been mapped in Early Cretaceous deposits located in the northeastern 27,000 km2 of the Colvile Basin, North Slope of Alaska. Using public domain 2-D seismic data, well logs, core photographs, and grain size data, depositional geometries within the Nanushuk and Torok formations were interpreted in order to constrain the transport conditions associated with progradation of the shoreline and construction of the continental margin out of detritus shed from the ancestral Brooks Range. Using STRATA, a synthetic stratigraphic modeling package, constructional clinoform geometries similar to those preserved in the North Slope clinoform volume (32,400 km3) were simulated. Sediment flux, marine and nonmarine diffusivities, and basin subsidence were systematically varied until a match was found for the foreset and topset slopes, as well as progradation rates over a 6 milion year period. The ability of STRATA to match the seismically interpreted geometries allows us to constrain measures of possible water and sediment discharges consistent with the observed development of the Early Cretaceous c1inoform suite. Simulations indicate that, in order to reproduce observed geometries and trends using constant input parameters, the subsidence rate must be very small, only a fraction of the most likely rate calculated from the seismic data. Constant sediment transport parameters can successfully describe the evolution of the prograding margin only in the absence of tectonic subsidence. However, further work is needed to constrain the absolute magnitude of these values and determine a unique solution for the NPR-A clinoforms.
    Keywords: Sediment transport ; Seismology ; Drill cores
    Repository Name: Woods Hole Open Access Server
    Type: Thesis
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  • 14
    Publication Date: 2022-05-26
    Description: Author Posting. © Acoustical Society of America, 2008. This article is posted here by permission of Acoustical Society of America for personal use, not for redistribution. The definitive version was published in Journal of the Acoustical Society of America 123 (2008): 667-678, doi:10.1121/1.2821975.
    Description: This paper introduces a perturbative inversion algorithm for determining sea floor acoustic properties, which uses modal amplitudes as input data. Perturbative inverse methods have been used in the past to estimate bottom acoustic properties in sediments, but up to this point these methods have used only the modal eigenvalues as input data. As with previous perturbative inversion methods, the one developed in this paper solves the nonlinear inverse problem using a series of approximate, linear steps. Examples of the method applied to synthetic and experimental data are provided to demonstrate the method's feasibility. Finally, it is shown that modal eigenvalue and amplitude perturbation can be combined into a single inversion algorithm that uses all of the potentially available modal data.
    Description: Funding for the research presented here was provided by the Office of Naval Research, and the WHOI Academic Programs Office.
    Keywords: Geophysical techniques ; Inverse problems ; Sediments ; Seismology
    Repository Name: Woods Hole Open Access Server
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  • 15
    Electronic Resource
    Electronic Resource
    New York, NY : Wiley-Blackwell
    Helvetica Chimica Acta 33 (1950), S. 23-24 
    ISSN: 0018-019X
    Keywords: Chemistry ; Organic Chemistry
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology
    Notes: Das Verhalten von BCG-Kulturen in Nährlösungen, die mit 35S indiziertes Sulfat enthalten, wird unter verschiedenen Bedingungen ermittelt.
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  • 16
    Electronic Resource
    Electronic Resource
    New York, NY : Wiley-Blackwell
    Helvetica Chimica Acta 33 (1950), S. 36-38 
    ISSN: 0018-019X
    Keywords: Chemistry ; Organic Chemistry
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology
    Notes: Für den Hauptanteil des Mono-bromierungsproduktes des Diallyls mit Bromsuccinimid wird die Konstitution des 3-Bromhexadiens-(1, 4) durch Ozonabbau bewiesen.
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  • 17
    Electronic Resource
    Electronic Resource
    New York, NY : Wiley-Blackwell
    Helvetica Chimica Acta 33 (1950), S. 25-36 
    ISSN: 0018-019X
    Keywords: Chemistry ; Organic Chemistry
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology
    Notes: Es wird über Erfahrungen mit einer fluorometrischen Methode zur Bestimmung von Uran berichtet und eine für Serienbestimmungen geeignete Arbeitsweise zur Abtrennung und Anreicherung von Uran angegeben. Mit Hilfe dieser Methoden wurde die Urankonzentration in einer Reihe von Gesteinen ermittelt.
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  • 18
    ISSN: 0018-019X
    Keywords: Chemistry ; Organic Chemistry
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology
    Notes: Es wird die Spaltung der Mutterkornalkaloide vom Polypetid-Typus mit Hydrazin beschrieben. Neben kleineren Spaltstücken wird die vollständige Peptidseitenkette als dreigliedriges saures Spaltstück erhalten, wobei das bei der totalen Hydrolyse mit Säuren und Alkalien als Ketosäure auftretende Glied nun in reduzierter Form erhalten wird. Aus Dihydro-ergotamin isolierte man Propionyl-L-phenyl-alanyl-L-prolin und aus den anderen Alkaloiden die entsprechend aufgebauten Peptidsäuren, deren Konstitution durch Synthese bewiesen werden konnte.
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  • 19
    Electronic Resource
    Electronic Resource
    New York, NY : Wiley-Blackwell
    Helvetica Chimica Acta 33 (1950), S. 130-139 
    ISSN: 0018-019X
    Keywords: Chemistry ; Organic Chemistry
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology
    Notes: Bei der Hydrierung der in β-oder γ-Stellung alkylierten, enolisierbaren α-Keto-γ-lactone bzw. ihrer Enolacetate in Gegenwart von Palladium-Calciumcarbonat oder Raney-Nickel entstehen quantitativ die entsprechenden α-Oxy-γ-lactone bzw. ihre Acetate. In neutralem, saurem und alkalischem Milieu wird immer nur das eine der beiden möglichen Diastereomeren erhalten.
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  • 20
    Electronic Resource
    Electronic Resource
    New York, NY : Wiley-Blackwell
    Helvetica Chimica Acta 33 (1950), S. 150-164 
    ISSN: 0018-019X
    Keywords: Chemistry ; Organic Chemistry
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology
    Notes: 1. Das Cinchonamin ist eine einsäurige Base C19H24ON2, welche im UV. ein für Indol-Derivate charakteristisches Absorptionsspektrum aufweist und zusätzlich zum Indol-Ring eine leicht hydrierbare Doppelbindung besitzt. Der Sauerstoff ist in Form einer Hydroxyl-Gruppe anwesend.
    Additional Material: 5 Ill.
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  • 21
    ISSN: 0018-019X
    Keywords: Chemistry ; Organic Chemistry
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology
    Notes: 1. Homogenat oder Suspensionen von Mitochondrien aus Rattenleber bilden aus Glutaminsäure Asparaginsäure. Die Asparaginsäure wurde durch Papierchromatographie nachgewiesen. Malonat hemmt die Reaktion.
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  • 22
    Electronic Resource
    Electronic Resource
    New York, NY : Wiley-Blackwell
    Helvetica Chimica Acta 33 (1950), S. 294-300 
    ISSN: 0018-019X
    Keywords: Chemistry ; Organic Chemistry
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology
    Notes: Durch Reduktion von Phenanthridin-jodmethylat mit LiAlH4 oder Zinn und Salzsäure, ferner durch Reduktion von N-Methyl-phenanthridon mit LiAlH4 entsteht dasselbe N-Methyl-o-dihydro-phenanthridin vom Smp. 48°. Die unter diesem Namen in der Literatur früher erwähnte Substanz ist ein Oxydationsprodukt des N-Methyl-o-dihydro-phenanthridins und geht allmählich in N-Methyl-phenanthridon über. Diese Oxydationsvorgänge wurden näher verfolgt.
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    Helvetica Chimica Acta 33 (1950), S. 337-342 
    ISSN: 0018-019X
    Keywords: Chemistry ; Organic Chemistry
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology
    Notes: β-Methyl-D-gluco-pyranosid wurde mit Distickstofftetroxyd oxydiert. Aus den Oxydationsprodukten konnten kristallisierte Derivate der D-Zuckersäure und des β-Methyl-D-glucuro-pyranosids isoliert werden. Das kristallisiertere β-Methyl-glucuronid wurde als Amid und Hydrazid charakterisiert und mit Perjodsäure abgebaut. Die Pyranosid-Struktur des β-Methyl-glucuronids wurde sichergestellt.
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    Helvetica Chimica Acta 33 (1950), S. 365-369 
    ISSN: 0018-019X
    Keywords: Chemistry ; Organic Chemistry
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology
    Notes: Durch Reduktion der Cyclanon-oxime mit Natrium und absolutem Alkohol wurden Cycloalkyl-amine mit 6 bis 18 Ringgliedern hergestellt. Von den hergestellten ringhomologen Cycloalkylaminen wurden die Dissoziationskonstanten in 80-proz. Methylcellosolve gemessen. Der Einfluss der Ringgrösse auf die Basizität der Cyclo-alkyl-amine ist gering.
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    Helvetica Chimica Acta 33 (1950), S. 398-404 
    ISSN: 0018-019X
    Keywords: Chemistry ; Organic Chemistry
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology
    Notes: Dans le mélange constituant la caséine du lait de vache, nous distinguons à côté des fractions α et β, décrites déjà par Warner, encore une fraction γ et une fraction δ (cette dernière identique à la protéose de Hammarsten). La fraction α se dédouble en αI et αII par précipitation à 40° en présence de sulfate d'ammonium.
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    Helvetica Chimica Acta 33 (1950), S. 10-13 
    ISSN: 0018-019X
    Keywords: Chemistry ; Organic Chemistry
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology
    Notes: Aus formaldehyd-vernetztem Oxypropylester der Pektinsäure werden durch alkalische Verseifung Natriumsalze verschiedenen Veresterungsgrades gewonnen. Die Quellung dieser Präparate in Wasser nimmt mit steigendem Veresterungsgrad deutlich zu. Diese Erscheinung wird auf eine Streckung der Fadenmolekeln bei Einführung von Estergruppen zurückgeführt.
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    Helvetica Chimica Acta 33 (1950), S. 13-16 
    ISSN: 0018-019X
    Keywords: Chemistry ; Organic Chemistry
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology
    Notes: La production des pigments caroténoïdes par le Bacille de la fléole, cultivé en milieu de Ingraham & Steenbock modifié, est nettement exaltée en présence de fer ou de manganèse; le cuivre active aussi cette biosynthèse mais, en sa présence, le Bacille végète et acidifie le milieu.
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    Helvetica Chimica Acta 33 (1950), S. 417-422 
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    Keywords: Chemistry ; Organic Chemistry
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    Helvetica Chimica Acta 33 (1950), S. 410-417 
    ISSN: 0018-019X
    Keywords: Chemistry ; Organic Chemistry
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology
    Notes: A) La Nadi-réaction ne constitue done pas un test spécifique de la cytochrome-oxydase; une Nadi-réaction négative «in vivo» peut résulter non seulement de l'absence de cytochrome-oxydase, mais aussi de la présence massive d'un système oxydo-réducteur à l'état réduit. L'effet cytochrome-oxydasique du CU+2 se distingue de celui de l'enzyme de Keilin par le fait qu'il n'exige pas, pour parachever l'oxydation du Nadi, le concours du cytochrome c.Etant donné la grande similitude de comportement de notre réaction catalytique spécifique à base de cuivre avec certaines réactions enzymatiques (pour la plupart oxydatives), ne doit-on pas incriminer plus souvent le cuivre d'être l'élément actif de ces systèmes? Nous pensons en particulier à la cytochrome-oxydase. Cette hypothèse élargit singulièrement la conception de Keilin, à savoir assimilation de l'indophénoloxydase à la cytochrome-oxydase.
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    Helvetica Chimica Acta 33 (1950), S. 433-443 
    ISSN: 0018-019X
    Keywords: Chemistry ; Organic Chemistry
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology
    Notes: Il est connu que le glutathion du germe de blé disparaît lorsque ce dernier est fermenté par de la levure. Nous avons établi qu'il s'agit d'une condensation entre ce tripeptide et un produit qui apparaît au cours de la fermentation. Nous avons isolé et cristallisé ce produit; il s'agit vraisemblablement d'un α-cétoaldéhyde encore inconnu.
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    Helvetica Chimica Acta 33 (1950), S. 462-465 
    ISSN: 0018-019X
    Keywords: Chemistry ; Organic Chemistry
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology
    Notes: Die Reindarstellung von Cäsiumalaun aus schwedischen Pollucit kann sehr einfach dadurch überwacht werden, dass man die spezifische Leitfähigkeit der Mutterlaugen verfogt. Dazu wird das abgeschiedene Kristallmehl mit seiner Mutterlauge 3 Tage bei 0° in Berührung gelassen und die Leitfähigkeit der überstehenden Lösung bei 25° bestimmt. Bei geeigneter Versuchsführung enthält der Cäsiumalaun nach 6 Kristallisationen keine anderen Alkalien mehr.
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    Helvetica Chimica Acta 33 (1950), S. 530-538 
    ISSN: 0018-019X
    Keywords: Chemistry ; Organic Chemistry
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology
    Notes: 1Der Mechanismus der Kupplungsreaktion wird auf Grund der Resonanztheorie erklärt und der Einfluss der Resonanzgrezstrukturen der Kupplungskomponente an zwei Beispielen erläutert.
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    Helvetica Chimica Acta 33 (1950), S. 550-554 
    ISSN: 0018-019X
    Keywords: Chemistry ; Organic Chemistry
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology
    Notes: Le titrage potentiométrique des solutions alcalines d'α-nitroso-β-naphtol a permis de calculer deux constantes de dissociation (formes tautomères) et la solubilité, au pH 9, de ce réactif.
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    Helvetica Chimica Acta 33 (1950), S. 557-559 
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    Keywords: Chemistry ; Organic Chemistry
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    Topics: Chemistry and Pharmacology
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    Helvetica Chimica Acta 33 (1950), S. 563-567 
    ISSN: 0018-019X
    Keywords: Chemistry ; Organic Chemistry
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology
    Notes: Es wurde die Zusammensetzung, Löslichkeit und Quellbarkeit von Calciumpektinaten verschiedenen Veresterungsgrades untersucht. Ihre Eigenschaften sind bei Annahme von „Calciumbrücken“ zwischen Carboxylgruppen benachbarter Fadenmolekeln nicht verständlich. Es wird darauf hingewiesen, dass allgemein bei Gelen von Polyelektrolyten fixierte Salzbindungen zwischen den Molekeln theoretisch und experimentell nicht begründet sind.
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    Helvetica Chimica Acta 33 (1950), S. 639-650 
    ISSN: 0018-019X
    Keywords: Chemistry ; Organic Chemistry
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology
    Notes: Aus den Samen von Strophanthus Eminii Asch. et Pax. konnten nach Einwirkung des wasserlöslichen Teils der darin enthaltenen Fermente von den 4 Hauptglykosiden 0,143% Periplocymarin, 0,182% Cymarol und 0,483% Emicymarin in kristallisierter Form isoliert werden. Aus dem Gewichtsverlust bei der Behandlung mit Girard's Reagens T ergibt sich ein Maximalgehalt an Cymarin von ca. 0,41%. Ausserdem wurden kleine Mengen Allo-cmicymarin, Periplogenin und Strophanthidol isoliert sowie 3 Stoffe. die als Nebenprodukt A, B und C bezeichnet wurden. Die stärker wasserlöslichen, erst mit Chloroform-Alkohol-Gemischen aus Wasser extrahierbaren Glykoside (15,7% der Gesamt-Rohglykoside) wurden noch nicht untersucht.
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    Helvetica Chimica Acta 33 (1950), S. 666-671 
    ISSN: 0018-019X
    Keywords: Chemistry ; Organic Chemistry
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology
    Notes: Aus den Samen von Strophanthus specious (Ward. et Harv.) Reber konnten nach Einwirkung des waserlöslichen Teils der darin enthaltenen Fermente insgesamt etwa 9,3% rohes Glykosidgemisch gewonnen werden. Bisher wurden zwei kristallisierte, herzaktive Glykoside daraus isoliert, die vorläufig als Substanzen Nr. 763 und Nr. 764 bezeichnet werden. Sie besitzen wahrscheinlich die Formeln C30H46O9 und C30H44O9, jeweils mit einer Methoxylgruppe.
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    Topics: Chemistry and Pharmacology
    Notes: Es wurde die Herstellung der isomeren ungesättigten Kohlenwasserstoffe IX, XXIV und XXV aus dem Triterpendiol Betulin (I) und der Oleanolsäure (II) beschrieben und eine Hypothese über die Biosynthese pentacyclischer Triterpene aufgestellt.
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    Helvetica Chimica Acta 33 (1950), S. 766-771 
    ISSN: 0018-019X
    Keywords: Chemistry ; Organic Chemistry
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology
    Notes: Es wird über eine neue Synthese des 1-Oxy-phenazins, ausgehend von Chlorbenzol, berichtet. Sie verläuft wie folgt: Chlorbenzol → Kaliumsalz der 2,6-Dinitrochlorbenzol-4-sulfosäure → Kaliumsalz der 2,6-Dinitroanilin-4-sulfosäure → 2,6-Dinitranilin. Letztere Verbindung wird mit o-Nitro-jodbenzol zu 2,6,2′-Trinitro-diphenylamin kondensiert. Durch katalytische Hydrierung und anschliessende milde Oxydation entsteht daraus 1-Aminophenazin, das durch energische Hydrolyse in 1-Oxy-phenazin übergeht.
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    Helvetica Chimica Acta 33 (1950), S. 776-781 
    ISSN: 0018-019X
    Keywords: Chemistry ; Organic Chemistry
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology
    Notes: 3-Oxyanthranilsäure, ein Zwischenprodukt bei der Bildung von Nikotinsäure aus Tryptophan, wird duch homogenisierte Rattenlberoxydiert. Das wirksame Enzym findet sich im Rückstand des zentrifugierten Homogenats. Es ist hitze- und cyanidempfindlich. Die Oxydation führt zu einem tief rot gefärbten Produkt. Kohlendioxyd und Ammoniak entstehen bei dieser Oxydation nicht.
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    Helvetica Chimica Acta 33 (1950), S. 821-833 
    ISSN: 0018-019X
    Keywords: Chemistry ; Organic Chemistry
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology
    Notes: 1. In tierischen Giften findet sich ein Agens, das Adenosintriphosphorsäure (ATP) dephosphoryliert und Fermentnatur besitzt.
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    Helvetica Chimica Acta 33 (1950), S. 854-857 
    ISSN: 0018-019X
    Keywords: Chemistry ; Organic Chemistry
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology
    Notes: Es wurden die experimentellen Grundlagen einer Arbeit von E. Baur & E. Herzfeld über die Labgerinnung der Milch als Reizleitung nachgeprüft. Es wurde festgestellt. dass nach der Labgerinnung keine labaktiven Abbauprodukte des Caseins in der Molke zu finden sind. Die beiden Autoren gelangten zu ihrem Fehlschluss, weil sie der Milchsäuregärung zu wenig Aufmerksamkeit schenkten.
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    Helvetica Chimica Acta 33 (1950), S. 878-888 
    ISSN: 0018-019X
    Keywords: Chemistry ; Organic Chemistry
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology
    Notes: Das aus den äthanol-leichtlöslichen Oxalaten der „starken Basenfraktionen“ aus Buxus sempervirens L. isolierte, sauerstoffreie Alkaloid L enthält eine Doppelbindung, ein sekundäres und ein tertiäres Stickstoffatom. Das eine ist aliphatisch gebunden, während das andere sich in einem Ring befinden dürfte.
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    Keywords: Chemistry ; Organic Chemistry
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology
    Notes: Pikrotoxinin, Brompikrotoxinin und α-Pikrotoxininsäure wurden mit Diazomethan umgesetzt. Bei Pikrotoxinin und Brompikrotoxinin konnte die Öffnung eines Lactonrings nachgewiesen werden. Beim Pikrotoxinin findet noch eine weitere Umwandlung eines sauerstoffhaltigen, noch unbekannten Systems statt, wobei man die Substanz C erhält. Diese wurde untersucht und die funktionellen Gruppen weitgehend bestimmt.
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    Helvetica Chimica Acta 33 (1950), S. 937-941 
    ISSN: 0018-019X
    Keywords: Chemistry ; Organic Chemistry
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology
    Notes: Aus den Ringen D und E der Oleanolsäure wurden das 2,2,7-Trimethyl-1,2,3,4-tetrahydro-naphtalin (IX) sowie die entsprechende 8-Carbonsäure XI gewonnen.
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    Helvetica Chimica Acta 33 (1950), S. 974-985 
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    Keywords: Chemistry ; Organic Chemistry
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology
    Notes: Es wurden die Gleichgewichte bei der Komplexbildung mit β,β′-Diamino-N,N′-diäthyl-äthylendiamin (= „trien“) und folgenden Metallkationen: Mn+2, Fe+2, Co+2, Ni+2, Cu+2, Cu+2, Zn+2, Cd+2, Hg+2 und Ag+ untersucht. Dieses Tetramin unterscheidet sich vom „tren“, das kompakter gebaut ist, vorallem dadurch, dass bie der Komplexbildung fast stets  -  eine Ausnahme machen nur Mn und Fe  -  Hydrogen-komplexe von der Zusammensetzung MHtrien auftreten. Die Bildungskonstanten von Mtrien sind fast alle kleiner als diejenigen von Mtren. Besonders gross ist der Unterschied bei Co, Zn und Cd. Kupfer bildet als einziges mit „tren“ einen stabileren Komplex als mit „tren“. Die Silberkomplexe der beiden Tetramine sind etwa von derselben Stabilität und es treten auch wieder die Partikeln, AgHtrien, AgH2trien und Ag2trien auf.
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    Helvetica Chimica Acta 33 (1950), S. 1035-1040 
    ISSN: 0018-019X
    Keywords: Chemistry ; Organic Chemistry
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology
    Notes: A. Le mélange d'acides qui résulte de la déshydratation de l'ester β-hydroxy-α,β-dihydro-géranique par le mélange PBr3-pyridine et de la saponification des esters non saturés donne sous l'action de l'acide formique, outre l'acide α-cyclogéranique, un autre acide cyclique C10H16O2. Les propriétés de ce dernier, que nous avons appelé acide allo-cyclogéranique, sont décrites.
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    Helvetica Chimica Acta 33 (1950), S. 1449-1457 
    ISSN: 0018-019X
    Keywords: Chemistry ; Organic Chemistry
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology
    Notes: Für die Halide des ein- und zweiwertigen Aluminiums wurden auf Grund vorhandener Daten und durch Vergleich mit analogen Verbindungen die Bildungswärmen ermittelt.
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    Helvetica Chimica Acta 33 (1950), S. 1481-1482 
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    Keywords: Chemistry ; Organic Chemistry
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    Helvetica Chimica Acta 33 (1950), S. 1494-1502 
    ISSN: 0018-019X
    Keywords: Chemistry ; Organic Chemistry
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology
    Notes: Es wird die Darstellung einer neuen, bei 32-33° schmelzenden 9, 11-Oktadekadiensäure aus Elaidinsäure und der 13, 15-Dokosadiensäure vom Schmelzpunkt 53-54° aus Brassidinsäure beschrieben.
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    Helvetica Chimica Acta 33 (1950), S. 108-116 
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    Keywords: Chemistry ; Organic Chemistry
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology
    Notes: Als Modellversuche für die Partialsynthese der natürlichen Mutterkornalkaloide vom Peptidtypus und zum Studium des Zusammenhanges zwischen Struktur der Peptidseitenkette und pharmakologischer Wirkung wurde eine grössere Anzahl von Peptiden der isomeren Lysergsäuren und Dihydro-lysergsäuren hergestellt, analysiert und charakterisiert.
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    Keywords: Chemistry ; Organic Chemistry
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology
    Notes: 1. α-Oxymethyl-indole IV, V und VI lassen sich in guter Ausbeute durch Reduktion der entsprechenden Indol-α-carbonsäure-ester I, II und III mit Lithiumaluminiumhydrid gewinnen.
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    Helvetica Chimica Acta 33 (1950), S. 178-184 
    ISSN: 0018-019X
    Keywords: Chemistry ; Organic Chemistry
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology
    Notes: Die neue Synthese der α-Bisdehydro-doisynolsäure nach Johnson ergibt nach unseren Untersuchungen neben dem erwarteten 1,2,3,4-Tetrahydro-phenanthren-derivat zur Hauptsache eine Cyclopentanonaphtalin-essigsäure, wie durch Dehydrierung und Verknüpfung des erhaltenen Produktes mit der C-Nor-bisdehydro-doisynolsäure von Billeter & Miescher gezeigt werden konnte.
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    Helvetica Chimica Acta 33 (1950), S. 207-210 
    ISSN: 0018-019X
    Keywords: Chemistry ; Organic Chemistry
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology
    Notes: L'α-amylase de salive humaine pure et la salive humaine brute ont exactement la même action sur les empois d'amidon, tant au point de vue de la viscosité que de l'apparition de groupes réducteurs. II en est conclu que la salive humaine ne contient ni «enzyme spécifiquement liquéfiant», ni «enzyme saccharifiant» (β-amylase).
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    Helvetica Chimica Acta 33 (1950), S. 232-232 
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    Keywords: Chemistry ; Organic Chemistry
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    Topics: Chemistry and Pharmacology
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    Helvetica Chimica Acta 33 (1950), S. 1787-1796 
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    Keywords: Chemistry ; Organic Chemistry
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology
    Notes: Die Acetylierung des β-Aminocrotonsäure-äthylesters mit Acetylchlorid und Pyridin liefert je nach den Bedingungen β-Acetylaminocrotonsäure-äthylester (stabile β-Form IX) und β-Acetylamino-iso-crotonsäure-äthylester (labile α-Form X). Daneben wird stets ca. 30 Prozent des C-acylierten Produktes, nämlich 2-Acetyl-3-amino-2-butensäure-äthylester (IV) gebildet.
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    Helvetica Chimica Acta 33 (1950), S. 273-285 
    ISSN: 0018-019X
    Keywords: Chemistry ; Organic Chemistry
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology
    Notes: N-substituierte Aminomethylen-bernsteinsäure-nitrile der allgemeinen Formel IV gehen unter der Einwirkung von Alkalialkoholaten in α-Aminopyrrolderivate VII über. Die in gleicher Weise erhältlichen Derivate des 1-Carbäthoxymethyl-2-amino-pyrrols (VIa und b) erleiden spontan einen weiteren Ringschluss und bilden bicyclische Lactame VIII. Letztere unterscheiden sich deutlich vom analog gebauten α-Acetylamino-pyrrol (XV) durch ihre stark erhöhte Acidität und längerwellige Absorption im UV.
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    Helvetica Chimica Acta 33 (1950), S. 300-301 
    ISSN: 0018-019X
    Keywords: Chemistry ; Organic Chemistry
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology
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    Helvetica Chimica Acta 33 (1950), S. 313-336 
    ISSN: 0018-019X
    Keywords: Chemistry ; Organic Chemistry
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology
    Notes: Die Konstitution der Sennoside A und B als Derivate des Dihydro-dianthrons wird bewiesen durch ihre reduktive Spaltung zu 9-Rheinanthron-Derivaten und durch Darstellung von 9,9′-Diacetyl-verbindungen mit Dianthranol-Struktur.
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    Helvetica Chimica Acta 33 (1950), S. 356-364 
    ISSN: 0018-019X
    Keywords: Chemistry ; Organic Chemistry
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology
    Notes: Durch Kondensation von Cyclanon-(2)-carbonsäure-(1)-estern mit der quaternären Base aus 1,1-Bis-(diäthylamino-methyl)-aceton wurden ungesättigte δ-Diketo-carbonsäure-ester IV mit 6, 7, 8, 9 und 13gliedrigem Ring erhalten. Diese cyclisierte man mit Salzsäure in Eisessig, wobei sich aus den 6 und 7 gliedrigen monocyclischen Ausgangsprodukten 3,4-Polymethylen-phenole VI, aus denjenigen mit 8. 9 und 13 Ringgliedern dagegen 2,6-Polymethylen-phenole V bildeten.
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    Helvetica Chimica Acta 33 (1950), S. 388-397 
    ISSN: 0018-019X
    Keywords: Chemistry ; Organic Chemistry
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology
    Notes: Ausgehend Tom tricyclischen Oxyketon von Köster & Logemann wurde eine Reihe verwandter, gesättigter und ungesättigter Oxyketone und Diketone der Phenanthrenreihe hergestellt.
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    Helvetica Chimica Acta 33 (1950) 
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    Keywords: Chemistry ; Organic Chemistry
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology
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    Keywords: Chemistry ; Organic Chemistry
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology
    Notes: Nous avons préparé. par la méthode de Königs et Knorr légèrement modifiée, les β-D-quinovosides du cholestérol et du cholestanol. Le β-D-quinovoside triacétylé de ľester benzhydrylique de ľacide Δ5-hydroxy-3 β-cholénique, obtenu de façon identique, fut transformé, par hydrogénation catalytique au charbon-palladium, en β-D-quinovoside triacétylé de ľacide hydroxy-3 β-allo-cholanique. Tous les hétérosides, de même que leurs dérivés acétylés. ont été obtenus sous la forme cristalline.
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    Helvetica Chimica Acta 33 (1950), S. 503-505 
    ISSN: 0018-019X
    Keywords: Chemistry ; Organic Chemistry
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology
    Notes: Es wird die Synthese des Thiazol-5-essigsäure-äthylesters durch eine direkte Thiazol-Kondensation durchgeführt. Ein Vergleich mit dem früher bei der Zersetzung des Thiazolyl-(5)-diazomethylketons in Gegenwart von Kupferoxyd erhaltenen und von uns als Thiazol-5-essigsäureester formulierten Produkt ergab die Verschiedenheit der Verbindungen. Von dem aus dem Thiazolyl-(5)-diazomethylketon entstandenen Produkt konnte ein 2,4-Dinitrophenylhydrazon erhalten werden, so dass diese Verbindung als Thiazolyl-(5)-ω-äthoxymethyl-keton zu formulieren ist.
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    Helvetica Chimica Acta 33 (1950), S. 522-529 
    ISSN: 0018-019X
    Keywords: Chemistry ; Organic Chemistry
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology
    Notes: Die Beschaffung authentischer Samen von Strophanthus Gerrardi Stapf. wird beschrieben. Nach Einwirkung des bei 0° wasserlöslichen Anteils der in den Samen enthaltenen Fermente wurden die folgenden 4 kristallisierten Stoffe in den angegebenen Ausbeuten erhalten .
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    Helvetica Chimica Acta 33 (1950), S. 555-557 
    ISSN: 0018-019X
    Keywords: Chemistry ; Organic Chemistry
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology
    Notes: Durch Reduktion von Thiamin-hydrochlorid mit Lithium-aluminiumhydrid entsteht o-Dihydro-thiamin, eine gut kristallisierte Verbindung von starkem Reduktionsvermögen, empfindlich gegen Säuren.
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    Helvetica Chimica Acta 33 (1950), S. 591-593 
    ISSN: 0018-019X
    Keywords: Chemistry ; Organic Chemistry
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology
    Notes: Es werden die Synthesen einiger mit p-Aminosalicylsäure verwandter Derivate beschrieben.
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    Helvetica Chimica Acta 33 (1950), S. 655-658 
    ISSN: 0018-019X
    Keywords: Chemistry ; Organic Chemistry
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology
    Notes: Einige Thioharnstoffe wurden an der Ratte unter einheitlichen Bedingungen auf ihre Toxizität geprüft. Die Toxizität dieser Verbindungen wurde mit der Wirkung auf Kartoffelphenoloxydase verglichen. Zwischen Toxizität und Wirkung von Thioharnstoffen auf Phenolase besteht keine strenge Beziehung.
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    Helvetica Chimica Acta 33 (1950), S. 687-699 
    ISSN: 0018-019X
    Keywords: Chemistry ; Organic Chemistry
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology
    Notes: Es wurden Zusammenhänge zwischen den Sojasapogenolen D und B einerseits sowie dem Sojasapogenol C und der α-Boswellinsäure anderseits festgestellt. Das Sojasapogenol D ist carbotetracyclisch und enthält einen Oxydring, der sich mit ätherspaltenden Reagenzien leicht öffnen lässt. Bei der Ätherspaltung findet gleichzeitig eine Cyclisierung statt. So führte die Einwirkung von Chlorwasserstoff auf Sojasapogenol-D-diacetat zum Δ13, 18-2, 24-Diacetoxy-x-chlor-oleanen (III) und die Umsetzung mit Borfluorid-Äther-Komplex in Acetanhydrid zum Δ13, 18-2, 24, x-Triacetoxy-oleanen (VIII). Die Verbindungen III und VIII wurden in das Δ13, 18-2, 24-Diacetoxy-oleanen (IV) übergeführt, welches auch aus dem Δ12, 13-2, 24-Diacetoxy-oleanen (VI) bereitet werden konnte. Für das Sojasapogenol D wird die Strukturformel I zur Diskussion gestellt.
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    Helvetica Chimica Acta 33 (1950), S. 725-736 
    ISSN: 0018-019X
    Keywords: Chemistry ; Organic Chemistry
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology
    Notes: ADurch Einwirkung von Thionylchlorid auf die Enolacetate und Enol-methyläther einiger α-Ketosäuren wurden die entsprechenden Säurechloride dargestellt.
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    Helvetica Chimica Acta 33 (1950), S. 781-781 
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    Keywords: Chemistry ; Organic Chemistry
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology
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    Helvetica Chimica Acta 33 (1950), S. 790-796 
    ISSN: 0018-019X
    Keywords: Chemistry ; Organic Chemistry
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology
    Notes: Für das Normalpotential des Natriums wird eine Neubestimmung durchgeführt. Sie ergibt den Wert von  -  2,7109 Volt (Potential der ges. Kalomelektrode: 244,3 mV gegen die Normal wasserstoffelektrode).
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    Helvetica Chimica Acta 33 (1950), S. 812-814 
    ISSN: 0018-019X
    Keywords: Chemistry ; Organic Chemistry
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology
    Notes: Allyl-phenyläther und Phenyl-benzyläther, die durch Lithiumaluminiumhydrid bei der Siedetemperatur des Äthyläthers nicht angegriffen werden, lassen sich in gewissem Umfange durch Lithiumaluminiumhydrid zu Phenol verseifen, wenn als Katalysator etwas Kobalt(II)-chlorid zugesetzt wird.
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    Helvetica Chimica Acta 33 (1950), S. 1070-1079 
    ISSN: 0018-019X
    Keywords: Chemistry ; Organic Chemistry
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology
    Notes: Es wird die Synthese der beiden diastereomeren 7,8-Bis-acetyl-amino-6-keto-nonansäuren (XI), ausgehend von Cyclohexanon, Nitromethan und Acetaldehyd, beschrieben. Die beiden als Zwischenprodukte auftretenden diastereomeren 1-Nitro-1-cyclohexenyl-2-acetyl-amino-propane (VIII) lassen sich ineinander überführen, so dass die Synthese stereochemisch kontrolliert werden kann.
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    Helvetica Chimica Acta 33 (1950), S. 1118-1126 
    ISSN: 0018-019X
    Keywords: Chemistry ; Organic Chemistry
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology
    Notes: Es wurden unter bestimmten Voraussetzungen lineare Differentialgleichungen für das Verhalten von Adsorbern und Reaktionsrohren abgeleitet. Die Integrale dieser Gleichungen wurden für gewisse Rand- und Anfangsbedingungen explizite angegeben.
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    Helvetica Chimica Acta 33 (1950), S. 1129-1136 
    ISSN: 0018-019X
    Keywords: Chemistry ; Organic Chemistry
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology
    Notes: Das in einer früheren Abhandlung beschriebene feste Bicyclofarnesol wird durch das Allophanat vom Smp. 181 - 182°, das flüssige Stereoisomere durch das Allophanat vom Smp. 191 - 192° charakterisiert.
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    Helvetica Chimica Acta 33 (1950), S. 1365-1369 
    ISSN: 0018-019X
    Keywords: Chemistry ; Organic Chemistry
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology
    Notes: Es wird die Darstellung einiger Monoaminotriazine-(1,3,5) beschrieben, einerseits durch Hydrierung der entsprechenden Dichloraminotriazine, anderseits durch Umsetzung des leichter erhältlichen Phenoxytriazins mit Aminen. Daneben werden einige Alkyl-dichlortriazine und deren Umsetzung zu Alkylamino-alkyltriazinen beschrieben. Die Alkylamino-triazine können am externen N mittels Natriumamid zu tertiären Basen alkyliert werden.
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    Helvetica Chimica Acta 33 (1950), S. 1386-1407 
    ISSN: 0018-019X
    Keywords: Chemistry ; Organic Chemistry
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology
    Notes: Es wurde eine grosse Zahl Aminoalkyl-imidazoline durch Umsetzung von Chloralkyl-imidazolinen mit Basen der aliphatischen, aromatischen und heterocyclischen Reihe dargestellt. Manche Vertreter zeigen ausgeprägte pharmakologische Eigenschaften, z.B. das 2-[N-Phenyl-N-benzyl-aminomethyl]-imidazolin („Antistin“), das 2-[Phenyl-aminomethyl]-imidazolin („Otrivin“) und das 2-[N-p-Tolyl-N-(m'-oxy-phenyl)-aminomethyl]-imidazolin („Regitin“).
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    Helvetica Chimica Acta 33 (1950), S. 1379-1385 
    ISSN: 0018-019X
    Keywords: Chemistry ; Organic Chemistry
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology
    Notes: Die Ätherspaltung des „Oestron-methyläthers c“ vom Smp. 162-161° und der damit identischen, aber noch unreinen Verbindung vom Smp. 146-147° (als Oestron-methyläther e bezeichnet) ergab je nach der angewandten Methode verschiedene Verbindungen. Nur bei der Behandlung mit Pyridinhydrochlorid entstand in beiden Fällen Oestron e vom Smp. 230-232°. Verseifung mit Bromwasserstoffsäure-Eisessig lieferte dagegen ein sauerstoffärmeres Produkt, das früher irrtümlich als „Oestron c“ bezeichnet wurde.
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    Helvetica Chimica Acta 33 (1950), S. 1433-1437 
    ISSN: 0018-019X
    Keywords: Chemistry ; Organic Chemistry
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology
    Notes: Es wird eine Totalsynthese eines ε1-Carotins beschrieben, welches sich vom β-Carotin darin unterscheidet, dass es an Stelle von 2 β-Jononringen 2 α-Jononringe enthält.
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    Helvetica Chimica Acta 33 (1950), S. 1458-1463 
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    Keywords: Chemistry ; Organic Chemistry
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology
    Notes: La formation des complexes cuivre(II)-α-nitroso-β-naphtol et fer (III)-α-nitroso-β-naphtol a été étudiée au potentiomètre et au p Hmètre. Des méthodes de dosages gravimétrique pour le cuivre et potentiométrique pour le cuivre(II) et le fer(III) ont été mises au point. La solubilité et la constante de dissociation du complexe cuivre-α-nitroso-β-naphtol ont été déterminées.
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    Helvetica Chimica Acta 33 (1950), S. 1698-1704 
    ISSN: 0018-019X
    Keywords: Chemistry ; Organic Chemistry
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology
    Notes: Bei der elektrophoretischen Untersuchung von Caseinatlösungen verschiedener Konzentration (0,3 bis 3,8%) findet man bei Auswertung der absteigenden Gradienten prozentual um so weniger β-Casein, je konzentrierter die Lösung ist. Dies ist weniger durch Grenzflächenanomalien als durch die reversible Komplexbildung zwischen α- und β-Casein bedingt, die in erwarteter Weise konzentrationsabhängig ist. Das gebundene β-Casein verschwindet auf den Diagrammen im α-Casein-Gradient. Interpolation der Werte auf die Konzentration gleich Null ergibt einen Maximalwert für das β-Casein von 25%. Dies dürfte dem wirklichen Gehalt des normalen Caseins entsprechen.
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    Helvetica Chimica Acta 33 (1950), S. 1730-1745 
    ISSN: 0018-019X
    Keywords: Chemistry ; Organic Chemistry
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology
    Notes: 1. Es wurde gezeigt, dass bei der thermischen Zersetzung des aus Dehydro-abietinsäure (I) zugänglichen tert.-Diphenyl-carbinols V ein Gemisch von Kohlenwasserstoffen C19H28 (VII) und C19H26 (IX, X oder XI) sowie Benzophenon und Benzhydrol entstehen. Die Oxydation von C19H28 mit Chromsäure führte zu einem Gemisch von sauren und neutralen Oxydationsprodukten. Aus den letzteren liessen sich die Ketone C19H26O (XII) und C18H22O2 (XIII) isolieren.
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    Helvetica Chimica Acta 33 (1950), S. 1773-1775 
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    Keywords: Chemistry ; Organic Chemistry
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology
    Notes: Es wird die Herstellung eines neuen Reagenzes, des N-Dimethylglycin-hydrazid-hydrochlorids beschrieben, das sich wie Girard-Reagenz zur Isolierung von Aldehyden und Ketonen eignet.
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    Helvetica Chimica Acta 33 (1950), S. 1823-1834 
    ISSN: 0018-019X
    Keywords: Chemistry ; Organic Chemistry
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology
    Notes: 1. Es wurden allgemeine Regeln für die Ableitung von Valenzsymmetriekoordinaten aufgestellt.
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    Helvetica Chimica Acta 33 (1950), S. 1847-1864 
    ISSN: 0018-019X
    Keywords: Chemistry ; Organic Chemistry
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology
    Notes: 2 Mol Acetessigester und 1 Mol Formaldehyd lassen sich in Gegenwart von 1 Mol NaOH und geringer Mengen sekundärer Base in verdünnter, wässeriger Lösung unter Bildung des Hagemann-Esters (IX) kondensieren. Diese Tatsache dient als Ausgangspunkt einer Hypothese über die Biosynthese der Steroide, wonach als wesentlichste Aufbauelemente Acetessigsäure und Formaldehyd anzusehen wären. Es ergeben sich damit enge Beziehungen im natürlichen Aufbau verschiedenartigster Naturstoffe.
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    Helvetica Chimica Acta 33 (1950), S. 1893-1910 
    ISSN: 0018-019X
    Keywords: Chemistry ; Organic Chemistry
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology
    Notes: Für Lanostadienol (C30H50O), einen zweifach ungesättigten, tetracyclischen Alkohol aus dem Wollfett der Schafe, wurde die Partialformel I zur Diskussion gestellt.
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    Helvetica Chimica Acta 33 (1950), S. 1937-1951 
    ISSN: 0018-019X
    Keywords: Chemistry ; Organic Chemistry
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology
    Notes: Aus den Dimethylestern der ω, ω'-Dicarboxy-dialkyläther XI, XV und XIX wurden durch Kondensation mit Natrium in Xylol die vielgliedrigen cyclischen Acyloine XX, XXI und XXII mit Sauerstoff als Ringglied hergestellt, welche nach den bekannten Verfahren in die Oxa-cyclanone XXIII, XXIV und XXV übergeführt werden konnten.
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    Helvetica Chimica Acta 33 (1950), S. 38-39 
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    Keywords: Chemistry ; Organic Chemistry
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    Topics: Chemistry and Pharmacology
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    Helvetica Chimica Acta 33 (1950), S. 67-75 
    ISSN: 0018-019X
    Keywords: Chemistry ; Organic Chemistry
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology
    Notes: Es wird die Synthese von rac. Dihydro-nor-lysergsäure und deren Aufspaltung in drei einheitliche, racemische Stereoisomere beschrieben. Diese Isomeren können den drei bekannten Dihydro-lysergsäuren natürlicher Herkunft sterisch zugeordnet und somit als rac. Dihydronor-lysergsäure, rac. Dihydro-nor-isolysergsäure(I) und rac. Dihydronor-isolysergsäure(II) bezeichnet werden. Die drei Säuren werden durch einige einfache Derivate charakterisiert.
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    Helvetica Chimica Acta 33 (1950), S. 100-100 
    ISSN: 0018-019X
    Keywords: Chemistry ; Organic Chemistry
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology
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  • 92
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    Helvetica Chimica Acta 33 (1950), S. 116-130 
    ISSN: 0018-019X
    Keywords: Chemistry ; Organic Chemistry
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology
    Notes: A. Es wird ein vereinfachtes Verfahren zur Darstellung von in β-Stellung nicht verzweigten α-Ketosäuren, sowie der entsprechenden Ester aus α-Äthoxalyl-fettsäureestern angegeben.
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  • 93
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    Helvetica Chimica Acta 33 (1950), S. 140-145 
    ISSN: 0018-019X
    Keywords: Chemistry ; Organic Chemistry
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology
    Notes: Das bei der katalytischen Hydrierung von α-Keto-β-methyl-γ-lacton erhaltene α-Oxy-β-methyl-γ-lacton wurde durch mehrstündiges Erhitzen der Natriumverbindung auf 144 - 148° epimerisiert. Die gleiche Umwandlung wurde auch über das p-Toluolsulfonat durch Umsetzen mit Natriumacetat in Eisessig und Alkoholyse der entstandenen Acetoxyverbindung ausgeführt. Das so gewonnene isomere Oxylacton, welches niedrigere Dichte, kleinern Brechungsindex und höhere Molekularrefraktion aufweist, ist reaktionsträger als das Ausgangslacton. Es wird deshalb angenommen, dass in der durch Epimerisieren gewonnenen Verbindung die Oxy- und die Methylgruppe zueinander in cis-, in dem bei der katalytischen Hydrierung gewonnenen dagegen in trans-Stellung stehen. Dieser Befund steht im Widerspruch zur Regel von Auwers-Skita.
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  • 94
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    Helvetica Chimica Acta 33 (1950), S. 171-177 
    ISSN: 0018-019X
    Keywords: Chemistry ; Organic Chemistry
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology
    Notes: Der leicht erfolgende Übergang des Zingiberens in ein bicyclisches Isomeres spricht gegen die Konstitutionsformel I. Durch Einwirkung von Acetylendicarbonsäuredimethylester auf Zingiberen bei 200° wurde 2, 6-Dimethyl-octadien-(2, 7) und 4-Methyl-phtalsäure-dimethylester erhalten. Deshalb wird für Zingiberen Formel XII vorgeschlagen.
    Additional Material: 3 Ill.
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  • 95
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    Helvetica Chimica Acta 33 (1950), S. 210-213 
    ISSN: 0018-019X
    Keywords: Chemistry ; Organic Chemistry
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology
    Notes: L'amylose qui se trouve dans l'amylopectine brute peut être éliminé quantitativement par adsorption sur de l'acide stéarique solide, ce qui permet d'obtenir de l'amylopectine exempte de traces d'amylose.
    Additional Material: 1 Ill.
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  • 96
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    Helvetica Chimica Acta 33 (1950), S. 231-231 
    ISSN: 0018-019X
    Keywords: Chemistry ; Organic Chemistry
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology
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  • 97
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    Helvetica Chimica Acta 33 (1950), S. 233-243 
    ISSN: 0018-019X
    Keywords: Chemistry ; Organic Chemistry
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology
    Notes: 1. In Rattenleberhomogenat wird aus zugesetztem DL-Serin aerob und anaerob Glykokoll gebildet.
    Additional Material: 1 Ill.
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  • 98
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    Helvetica Chimica Acta 33 (1950), S. 256-261 
    ISSN: 0018-019X
    Keywords: Chemistry ; Organic Chemistry
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology
    Notes: Es wurde eine Reihe von z. T. neu dargestellten Verbindungen, die als isoster mit p-Aminobenzoesäure bzw. mit p-Aminobenzoesäure-äthylester zu formulieren sind, auf ihre tuberkulostatische Wirkung geprüft.
    Additional Material: 1 Tab.
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  • 99
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    Helvetica Chimica Acta 33 (1950), S. 286-290 
    ISSN: 0018-019X
    Keywords: Chemistry ; Organic Chemistry
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology
    Notes: Das Scillirosid, das sehr aktive ratizide und herzwirksame Hauptglykosid aus der roten Meerzwiebel, wird durch Enzyme der Coronilla- und der Luzernesamen, welche die Bindung zwischen Aglykon und Glucose angreifen, in das Aglykon Scillirosidin und Glucose zerlegt. Das erst durch diese enzymatische Spaltung zugänglich gewordene Scillirosidin besitzt eine gegenüber Scillirosid gesteigerte, sehr hohe Wirksamkeit auf das Herz.
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    Helvetica Chimica Acta 33 (1950), S. 302-306 
    ISSN: 0018-019X
    Keywords: Chemistry ; Organic Chemistry
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology
    Notes: Aus L-Cystein und d, l-α-Jodpropionsäure bzw. l(-)-α-Brompropionsäure wurden zwei diastereomere [1-Carboxy-äthyl-(1)]-L-S-cysteine und aus L-Cystein und l-α-Brom-isocapronsäure[l-1-Carboxy-3-methyl-butyl-(1)]-L-S-cystein hergestellt und aus diesen Verbindungen die entsprechenden Sulfoxyde bereitet. Ausserdem wurde L-S-Propyl-cysteinol synthetisiert.
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