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  • *Ecosystem  (112)
  • 03. Hydrosphere::03.04. Chemical and biological::03.04.06. Hydrothermal systems
  • 04. Solid Earth::04.04. Geology::04.04.10. Stratigraphy
  • 04. Solid Earth::04.06. Seismology::04.06.08. Volcano seismology
  • Acoustics
  • Applied geophysics
  • Binding Sites
  • Data analysis / ~ processing
  • Fluids
  • Schussler
  • Textbook of geophysics
  • American Association for the Advancement of Science (AAAS)  (165)
  • Elsevier  (24)
  • Springer  (4)
  • Cambridge U. Press
  • Cambridge Univ. Press
  • Kluwer
  • Soc. of Exploration Geophys.
  • W.H. Freeman
  • 2020-2023
  • 2010-2014  (174)
  • 2000-2004
  • 1980-1984  (19)
  • 2010  (174)
  • 1984  (19)
Collection
Keywords
Publisher
Years
  • 2020-2023
  • 2010-2014  (174)
  • 2000-2004
  • 1980-1984  (19)
Year
  • 1
    Publication Date: 2020-11-16
    Description: Active volcanoes characterized by open conduit conditions generate sonic and infrasonic signals, whose investigation provides useful information for both monitoring purposes and studying the dynamics of explosive processes. In this work, we discuss the automatic procedures implemented for a real-time application to the data acquired by a permanent network of five infrasound stations running at Mt. Etna volcano. The infrasound signals at Mt. Etna consist in amplitude transients, called infrasound events. The adopted procedure uses a multi-algorithm approach for event detection, counting, characterization and location. It is designed for an efficient and accurate processing of infrasound records provided by single-site and array stations. Moreover, the source mechanism of these events can be investigated off-line or in near real-time by using three different models: i) Strombolian bubble; ii) resonating conduit and iii) Helmholtz resonator. The infrasound waveforms allow us to choose the most suitable model, to get quantitative information about the source and to follow the time evolution of the source parameters.
    Description: Published
    Description: 1215–1231
    Description: 6V. Pericolosità vulcanica e contributi alla stima del rischio
    Description: JCR Journal
    Description: open
    Keywords: infrasound ; monitoring system ; Mt. Etna ; 04. Solid Earth::04.06. Seismology::04.06.08. Volcano seismology
    Repository Name: Istituto Nazionale di Geofisica e Vulcanologia (INGV)
    Type: article
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  • 2
    Publication Date: 2021-01-07
    Description: The quaternary volcanic complex of Mount Amiata is located in southern Tuscany (Italy) and represents the most recent manifestation of the Tuscan Magmatic Province. The region is characterised by a large thermal anomaly and by the presence of numerous CO2-rich gas emissions and geothermal features, mainly located at the periphery of the volcanic complex. Two geothermal systems are located, at increasing depths, in the carbonate and metamorphic formations beneath the volcanic complex. The shallow volcanic aquifer is separated from the deep geothermal systems by a low permeability unit (Ligurian Unit). A measured CO2 discharge through soils of 1.8 109 mol a 1 shows that large amounts of CO2 move from the deep reservoir to the surface. A large range in d13CTDIC ( 21.07 to +3.65) characterises the waters circulating in the aquifers of the region and the mass and isotopic balance of TDIC allows distinguishing a discharge of 0.3 109 mol a 1 of deeply sourced CO2 in spring waters. The total natural CO2 discharge (2.1 109 mol a 1) is slightly less than minimum CO2 output estimated by an indirect method (2.8 109 mol a 1), but present-day release of 5.8 109 mol a 1 CO2 from deep geothermal wells may have reduced natural CO2 discharge. The heat transported by groundwater, computed considering the increase in temperature from the infiltration area to the discharge from springs, is of the same order of magnitude, or higher, than the regional conductive heat flow (〉200 mWm 2) and reaches extremely high values (up to 2700mWm 2) in the north-eastern part of the study area. Heat transfer occurs mainly by conductive heating in the volcanic aquifer and by uprising gas and vapor along fault zones and in those areas where low permeability cover is lacking. The comparison of CO2 flux, heat flow and geological setting shows that near surface geology and hydrogeological setting play a central role in determining CO2 degassing and heat transfer patterns.
    Description: Published
    Description: 860–875
    Description: 1.2. TTC - Sorveglianza geochimica delle aree vulcaniche attive
    Description: 2.4. TTC - Laboratori di geochimica dei fluidi
    Description: 4.5. Studi sul degassamento naturale e sui gas petroliferi
    Description: JCR Journal
    Description: reserved
    Keywords: Carbon dioxide degassing ; Monte Amiata ; 03. Hydrosphere::03.04. Chemical and biological::03.04.05. Gases ; 03. Hydrosphere::03.04. Chemical and biological::03.04.06. Hydrothermal systems ; 04. Solid Earth::04.04. Geology::04.04.12. Fluid Geochemistry ; 04. Solid Earth::04.08. Volcanology::04.08.06. Volcano monitoring
    Repository Name: Istituto Nazionale di Geofisica e Vulcanologia (INGV)
    Type: article
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  • 3
    Publication Date: 2020-11-12
    Description: Fogo volcano is an active central volcano, with a lake filled caldera, in the central part of São Miguel Island, Azores, whose current activity is limited to hydrothermal manifestations such as active fumarolic fields, thermal and CO2 cold springs and soil diffuse degassing areas. It is affected by important active tectonic structures, with high seismic activity and practically continuous micro-seismicity. A recurrent feature from the seismicity observed in volcanic regions is the occurrence of clusters of similar earthquakes, whose origin can be attributed to the repeated action of a similar source mechanism at the same focal area. Doublets/multiplets were identified in this study within a catalogue of small magnitude (usually 〈 3) volcano tectonic events recorded in 2003–2004 by a selection of stations around Fogo volcano. All events have been cross-correlated and pairs whose waveforms exhibited a cross-correlation coefficient equal to or higher than 0.9 were analysed using the coda-wave interferometry technique. Subtle velocity variations found between events highlight a seasonal cycle of the velocity patterns, with lower velocity in winter time and higher velocity during summer months. Those results, together with quantitative differences between the same doublets at different stations, exhibit an excellent correlation with rainfall. A seasonal effect can also be broadly seen in the seismicity occurrence, and some of the swarms recorded over the two year period occur during the wettest season or close to episodes of abundant (above average) rainfall. Moreover, temporal and spatial analysis of several swarms highlighted the lack of any mainshock–aftershock sequence and organized migration of the hypocenters. This is suggestive of a very heterogeneous stress field. Vp/Vs is found to be lower than usually observed in volcanic areas, an occurrence likely related to the presence of steamy fluid associated with the geothermal system. Taken together, these observations suggest that pore pressurisation plays a major role in controlling a considerable part of the recorded seismicity. The geothermal fluids around Fogo massif have been identified as derived from meteoric water, which infiltrates through Fogo Lake and the volcano flanks and flows from south to north on the northern flank. All those elements seem to point to a role played by rainfall in triggering seismicity at São Miguel, possibly through pressure changes at depth in response to surface rain and/or an interaction with the geothermal system.
    Description: Published
    Description: 231-246
    Description: 1.4. TTC - Sorveglianza sismologica delle aree vulcaniche attive
    Description: JCR Journal
    Description: reserved
    Keywords: velocity changes ; rainfall ; volcano seismicity ; triggered seismicity ; Azores archipelago ; 04. Solid Earth::04.06. Seismology::04.06.08. Volcano seismology
    Repository Name: Istituto Nazionale di Geofisica e Vulcanologia (INGV)
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  • 4
    Publication Date: 2021-01-25
    Description: Continuous marine successions covering the Middle Miocene Climate Transition (MMCT; ∼15–13.7 Ma) are scarce and the lack of a high-resolution magnetobiostratigraphic framework hampers the construction of astronomically tuned age models for this time interval. The La Vedova High Cliff section, exposed along the coast of the Cònero Riviera near Ancona (Italy), is one of the few Mediterranean sections covering the critical time interval of the MMCT. Starting from an initial magnetobiostratigraphic age model, a robust astronomical tuning was constructed for the interval between 14.2 and 13.5 Ma, using geochemical element data and time series analysis. A shift in δ18O of bulk sediment towards heavier values occurs between ∼13.92 and 13.78 Ma and could be related to the Mi3b oxygen isotope event, which reflects the rapid expansion of the East Antarctic Ice Sheet in the middle Miocene. The onset of the CM6 carbon excursion is reflected in the bulk record by a rapid increase in δ13C at 13.86 Ma. Our results confirm the proposition that these events coincide with a 405-kyr minimum in eccentricity and a node in obliquity related to the ∼1.2 Myr cycle. From 13.8 Ma onwards, distinct quadruplet cycles containing sapropelitic sediments were deposited. This may suggest a causal connection between the main middle Miocene cooling step and the onset of sapropel formation in the Mediterranean.
    Description: Published
    Description: 249–261
    Description: 2.2. Laboratorio di paleomagnetismo
    Description: JCR Journal
    Description: restricted
    Keywords: Middle Miocene ; Mediterranean ; astronomical tuning ; paleomagnetism ; biostratigraphy ; environmental changes ; orbital forcing ; sapropels ; 04. Solid Earth::04.04. Geology::04.04.10. Stratigraphy ; 04. Solid Earth::04.05. Geomagnetism::04.05.06. Paleomagnetism
    Repository Name: Istituto Nazionale di Geofisica e Vulcanologia (INGV)
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  • 5
    Publication Date: 2020-11-12
    Description: The number of tornillo events has recently increased at the Vulcano Island, Italy. While only 15 tornillos were recorded during 2004–2006, 584 events occurred in 2007–2008. They were located just below La Fossa Crater at depths ranging between 0.1 and 1 km b.s.l. During two intervals in 2007–2008 increases in the number of tornillos took place at the same time as temperature and geochemical anomalies were observed. The spectral content of the tornillos, generally characterized by one–two dominant spectral peaks near 6 and 10 Hz, varied over time, with changes also noted in the quality factors. The simplest source mechanism proposed for tornillos is the free eigenvibration of a fluid volume within a crack or a conduit. Based on this model, we propose a causal relationship between the temperature and geochemical anomalies and the increases in numbers of tornillos. As the amount of hydrothermal fluids increases during the anomalies, the upward flux of fluids grows. The consequent changes in the pressure, temperature and dynamics of the system of cracks and conduits result in the generation of tornillos. Based on the fluid-filled crack/conduit model, the shallow depths of the sources and the values of the quality factors, the fluid within the resonant crack/conduit was inferred to be an ash–gas or water droplet–gas mixture. Moreover, the observed variations in the wavefield can be caused by small changes in the location of the source, in the source mechanism, or in the medium in between the source and the seismic station. Finally, another peculiar feature of tornillos is the amplitude modulation that can be explained as a result of a beating phenomenon.
    Description: Published
    Description: 377-393
    Description: 3V. Proprietà chimico-fisiche dei magmi e dei prodotti vulcanici
    Description: JCR Journal
    Description: reserved
    Keywords: Tornillos ; Vulcano Island ; Hydrothermal system ; Volcano seismology ; 04. Solid Earth::04.06. Seismology::04.06.08. Volcano seismology
    Repository Name: Istituto Nazionale di Geofisica e Vulcanologia (INGV)
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  • 6
    Publication Date: 2021-01-27
    Description: Na–HCO3–CO2-rich thermomineral waters issue in the N of Portugal, within the Galicia-Trás-os-Montes region, linked to a major NNE-trending fault, the so-called Penacova-Régua-Verin megalineament. Along this tectonic structure different occurrences of CO2-rich thermomineral waters are found: Chaves hot waters (67 °C) and also several cold (16.1 °C) CO2-rich waters. The δ2H and δ18O values of the thermomineral waters are similar to those of the local meteoric waters. The chemical composition of both hot and cold mineral waters suggests that water–rock reactions are mainly controlled by the amount of dissolved CO2 (g) rather than by the water temperature. Stable carbon isotope data indicate an external CO2 inorganic origin for the gas. δ13CCO2 values ranging between −7.2‰ and −5.1‰ are consistent with a two-component mixture between crustal and mantle-derived CO2. Such an assumption is supported by the 3He/4He ratios measured in the gas phase, are between 0.89 and 2.68 times the atmospheric ratio (Ra). These ratios which are higher than that those expected for a pure crustal origin (≈0.02 Ra), indicating that 10 to 30% of the He has originated from the upper mantle. Release of deep-seated fluids having a mantle-derived component in a region without recent volcanic activity indicates that extensive neo-tectonic structures originating during the Alpine Orogeny are still active (i.e., the Chaves Depression).
    Description: Published
    Description: 49-56
    Description: 4.5. Studi sul degassamento naturale e sui gas petroliferi
    Description: JCR Journal
    Description: reserved
    Keywords: CO2-rich thermomineral waters ; mantle volatiles ; isotopes ; Chaves geothermal system ; N-Portugal ; 03. Hydrosphere::03.02. Hydrology::03.02.02. Hydrological processes: interaction, transport, dynamics ; 03. Hydrosphere::03.02. Hydrology::03.02.03. Groundwater processes ; 03. Hydrosphere::03.04. Chemical and biological::03.04.03. Chemistry of waters ; 03. Hydrosphere::03.04. Chemical and biological::03.04.06. Hydrothermal systems ; 04. Solid Earth::04.08. Volcanology::04.08.01. Gases
    Repository Name: Istituto Nazionale di Geofisica e Vulcanologia (INGV)
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  • 7
    Publication Date: 2017-04-04
    Description: The Piànico-Sèllere is a lacustrine succession from northern Italy that records a sequence of climatic transitions across two Pleistocene glacial stages. The intervening interglacial stage is represented by well-preserved varves with calcitic (summer) and clastic (winter) laminae. There is a tight coupling between climate-driven lithologic changes and magnetic susceptibility variations, and stable paleomagnetic components were retrieved from all investigated lithologies including the largely diamagnetic calcite varves. These components were used to delineate a sequence of magnetic polarity reversals that was interpreted as a record of excursions of the Earth’s magnetic field. Comparison of the magnetostratigraphic results with previously published data allows discussion of two possible models which have generated controversy regarding the age of the Piànico Formation. The data indicates that the Piànico Formation magnetostratigraphy correlates to geomagnetic field excursions across the Brunhes/Matuyama transition, and consequently the Piànico interglacial correlates to marine isotope stage 19. This correlation option is substantially consistent with K-Ar radiometric age estimates recently obtained from a tepha layer interbedded in the Piànico Formation. The alternative option, considering the Piànico interglacial correlative to marine isotope stage 11 within the Brunhes Chron as supported by tephrochronological dating reported in the literature, is not supported by the magnetostratigraphic results.
    Description: Published
    Description: 44-53
    Description: 3.2. Tettonica attiva
    Description: JCR Journal
    Description: open
    Keywords: Piànico Formation ; Pleistocene ; magnetostratigraphy ; polarity excursions ; Brunhes Chron ; Southern Alps ; 04. Solid Earth::04.04. Geology::04.04.02. Geochronology ; 04. Solid Earth::04.04. Geology::04.04.08. Sediments: dating, processes, transport ; 04. Solid Earth::04.04. Geology::04.04.10. Stratigraphy ; 04. Solid Earth::04.05. Geomagnetism::04.05.02. Geomagnetic field variations and reversals ; 04. Solid Earth::04.05. Geomagnetism::04.05.06. Paleomagnetism
    Repository Name: Istituto Nazionale di Geofisica e Vulcanologia (INGV)
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  • 8
    Publication Date: 2017-04-04
    Description: Na–HCO3–CO2-rich thermomineral waters issue in the N of Portugal, within the Galicia-Trás-os-Montes region, linked to a major NNE-trending fault, the so-called Penacova-Régua-Verin megalineament. Along this tectonic structure different occurrences of CO2-rich thermomineral waters are found: Chaves hot waters (67 °C) and also several cold (16.1 °C) CO2-rich waters. The δ2H and δ18O values of the thermomineral waters are similar to those of the local meteoric waters. The chemical composition of both hot and cold mineral waters suggests that water–rock reactions are mainly controlled by the amount of dissolved CO2 (g) rather than by the water temperature. Stable carbon isotope data indicate an external CO2 inorganic origin for the gas. δ13CCO2 values ranging between −7.2‰ and −5.1‰ are consistent with a two-component mixture between crustal and mantle-derived CO2. Such an assumption is supported by the 3He/4He ratios measured in the gas phase, are between 0.89 and 2.68 times the atmospheric ratio (Ra). These ratios which are higher than that those expected for a pure crustal origin (≈0.02 Ra), indicating that 10 to 30% of the He has originated from the upper mantle. Release of deep-seated fluids having a mantle-derived component in a region without recent volcanic activity indicates that extensive neo-tectonic structures originating during the Alpine Orogeny are still active (i.e., the Chaves Depression).
    Description: In press
    Description: 4.5. Studi sul degassamento naturale e sui gas petroliferi
    Description: JCR Journal
    Description: open
    Keywords: CO2-rich thermomineral waters ; mantle volatiles ; isotopes ; Chaves geothermal 9 system ; 03. Hydrosphere::03.02. Hydrology::03.02.02. Hydrological processes: interaction, transport, dynamics ; 03. Hydrosphere::03.02. Hydrology::03.02.03. Groundwater processes ; 03. Hydrosphere::03.04. Chemical and biological::03.04.03. Chemistry of waters ; 03. Hydrosphere::03.04. Chemical and biological::03.04.05. Gases ; 03. Hydrosphere::03.04. Chemical and biological::03.04.06. Hydrothermal systems
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  • 9
    Publication Date: 2017-04-04
    Description: The Miano borehole of 1047 m depth is located close to the river Parma in the Northern Apennines, Italy. A measuring station is installed to observe the discharge of fluids continuously since November 2004. The upwelling fluid of this artesian well is a mixture of thermal water and methane as main components. In non-seismogenic areas, we would expect a relative constant fluid emission perhaps overlaid with long term variations from that kind of deep reservoirs during the time. However, the continuously record of the fluid emission, in particular the water discharge, the gas flow rate and the water temperature, show periods of stable values interrupted by anomalous periods of fluctuations in the recorded parameters. The anomalous variations of these parameters are of low amplitude in comparison to the total values but significant in their long-term trend. Meteorological influences of rain and barometric pressure were not detected in recorded data probably due to reservoir depth and relatively high reservoir overpressure. Influences due to the ambient temperature after the discharge were evaluated by statistical analysis. We consider that recorded changes in fluid emission parameters can be interpreted as a mixing process of different fluid components in depth by variations in pore pressure as result of seismogenic stress variation. Local seismicity was analyzed in comparison to fluid’s physico-chemical data. The analysis supports the idea of an influence to fluid transport conditions due to geodynamic processes exist. Water temperature data show frequent anomalies probably connected with possible precursory phenomena of local seismic events.
    Description: In press
    Description: 3.2. Tettonica attiva
    Description: JCR Journal
    Description: open
    Keywords: Fluids ; Earthquakes ; Continous monitoring ; 04. Solid Earth::04.04. Geology::04.04.12. Fluid Geochemistry
    Repository Name: Istituto Nazionale di Geofisica e Vulcanologia (INGV)
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  • 10
    Publication Date: 2017-04-04
    Description: Mercury is outstanding among the global environmental pollutants of continuing concern. Although degassing of active volcanic areas represents an important natural source of mercury into the atmosphere, still little is known about the amount and behaviour of Hg in volcanic aquifers, especially regarding its chemical speciation. In order to assess the importance of mercury emissions from active volcanoes, thermal waters were sampled in the area surrounding La Solfatara, Pozzuoli bay. This is the most active zone of the Phlegrean Fields complex (coastal area north–west of Naples), with intense hydrothermal activity at present day. Studied groundwaters show total Hg (THg) concentrations range from 56 to 171 ng/l and are lower than the 1000 ng/l threshold value for human health protection fixed by the World Health Organization (WHO, 1993). We also carefully discriminated the different aqueous species of Hg in the collected water samples. Besides, original data on Hg determination in gaseous manifestations at La Solfatara crater are also reported. We measured volcanogenic mercury concentration and Hg/Stot ratio both in the volcanic plume and in fumarolic condensates in order to better constrain Hg reactivity once emitted into the atmosphere. Data on Hg/Stot reveal that there is no significant difference between Hg volcanic composition at the venting source (fumaroles) and in near-vent diluted volcanic plumes (1.6×10−5 and 1.9×10−5, respectively), suggesting that there is limited Hg chemical processing in volcanic fumarole plumes, at least on the timescales of a few seconds investigated here. Combining the mean fumaroles Hg/CO2 mass ratio of about 1.3×10−8 (molar ratio: 2.1×10−9) with the hydrothermal soil diffuse CO2 degassing of the area, the annual Hg flux from La Solfatara is estimated as 7 kg y−1 (0.007 t y−1). Current mercury emission from La Solfatara volcano represents a very small contribution to the estimated global volcanic budget for this element, and the estimated Hg flux is considerably lower than that estimated from open-conduit active basaltic volcanoes.
    Description: Published
    Description: 250–260
    Description: 1.2. TTC - Sorveglianza geochimica delle aree vulcaniche attive
    Description: 2.4. TTC - Laboratori di geochimica dei fluidi
    Description: 4.5. Studi sul degassamento naturale e sui gas petroliferi
    Description: JCR Journal
    Description: reserved
    Keywords: hydrothermal waters ; total mercury ; mercury speciation ; fumaroles ; 03. Hydrosphere::03.04. Chemical and biological::03.04.05. Gases ; 03. Hydrosphere::03.04. Chemical and biological::03.04.06. Hydrothermal systems ; 04. Solid Earth::04.04. Geology::04.04.12. Fluid Geochemistry ; 04. Solid Earth::04.08. Volcanology::04.08.06. Volcano monitoring
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  • 11
    Publication Date: 2017-04-04
    Description: The soil CO2 degassing is affected by processes of isotope exchange and fractionation during transport across the soil, which can deeply modify the pristine isotope composition. This has been observed in the Solfatara volcano, upon a field survey of 110 points, where the CO2 flux was measured, together with temperature, CO2 concentration and oxygen and carbon isotopes within the soil. Furthermore, in some selected sites, the measurements were made at different depths, in order to analyze vertical gradients. Oxygen isotope composition appears controlled by exchange with soil water (either meteoric or fumarolic condensate), due to the fast kinetic of the isotopic equilibrium between CO2 and water. Carbon isotope composition is reliably controlled by transport-driven fractionation, due to the differences in diffusion coefficients between 13C16O2 and 12C16O2. We model the processes affecting CO2 transport across the soil in La Solfatara volcano by means of the Dusty Gas Model applied to a multicomponent system, to evaluate the reciprocal effect on diffusion of involved gases, i.e. 12C16O2, 13C16O2, N2 and O2 in our case. Both numerical and simplified analytical solutions of the equations based on the Dusty Gas Model are given. The modeling results fit well with the experimental data and put in evidence an isotope fractionation of carbon up to about þ4:4& with respect to the source value in the soil gas. This fractionation is independent from the entity of the CO2 flux, and occurs as long as a concentration gradient exists within the soil. On these grounds, the Dusty Gas Model can be applied to whichever diffusing gas mixture to evaluate the extent of chemical and/or isotopic fractionation that can affect ascending gases upon diffusion in any geothermal, volcanic or tectonic area.
    Description: Published
    Description: 3521-3528
    Description: 1.2. TTC - Sorveglianza geochimica delle aree vulcaniche attive
    Description: JCR Journal
    Description: reserved
    Keywords: isotope exchange ; degassing ; 03. Hydrosphere::03.04. Chemical and biological::03.04.05. Gases ; 03. Hydrosphere::03.04. Chemical and biological::03.04.06. Hydrothermal systems ; 03. Hydrosphere::03.04. Chemical and biological::03.04.08. Instruments and techniques
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  • 12
    Publication Date: 2017-04-04
    Description: Active volcanoes characterized by open conduit conditions generate sonic and infrasonic signals, whose investigation provides useful information for both monitoring purposes and studying the dynamics of explosive processes. In this work, we discuss the automatic procedures implemented for a real-time application to the data acquired by a permanent network of five infrasound stations running at Mt. Etna volcano. The infrasound signals at Mt. Etna consist in amplitude transients, called infrasound events. The adopted procedure uses a multi-algorithm approach for event detection, counting, characterization and location. It is designed for an efficient and accurate processing of infrasound records provided by single-site and array stations. Moreover, the source mechanism of these events can be investigated off-line or in near real-time by using three different models: (1) Strombolian bubble; (2) resonating conduit and (3) Helmholtz resonator. The infrasound waveforms allow us to choose the most suitable model, to get quantitative information about the source and to follow the time evolution of the source parameters.
    Description: Published
    Description: 1215–1231
    Description: 1.4. TTC - Sorveglianza sismologica delle aree vulcaniche attive
    Description: JCR Journal
    Description: reserved
    Keywords: Infrasound ; monitoring system ; Mt. Etna volcano ; 04. Solid Earth::04.06. Seismology::04.06.08. Volcano seismology ; 04. Solid Earth::04.08. Volcanology::04.08.06. Volcano monitoring ; 04. Solid Earth::04.08. Volcanology::04.08.07. Instruments and techniques
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  • 13
    Publication Date: 2017-04-04
    Description: Stromboli is considered one of the most active volcanoes in the world, and its persistent but moderate explosive activity is only interrupted by occasional episodes of more vigorous activity accompanied by lava flows. A new effusive eruption began in late February, 2007 and was characterised by intense seismic activity throughout the whole period. The accurate seismic signals analysis showed the presence of families of events with similar waveform signatures (i.e. multiplets) located beneath the crater region. Since traditional location techniques do not allow obtaining reliable hypocentres, our analysis focused on high precision locations of the seismicity, in order to better define the source geometry of the events. Hypocentres, therefore, have been relocated considering two steps: the first, based on a robust probabilistic approach, is used to find the absolute position of the clusters; the second exploits a master-event concept for the relative location of the events. Finally, the shape of the clusters and the temporal migration of the foci were correlated with the eruptive phases. The results show that the occurrence of a cluster of events is related to the opening and closure of a vent opened in the Sciara del Fuoco slope and, in particular, to the intrusion of a dike injected by central conduit in a radial direction, whereas another cluster lies in a narrow vertical volume positioned under the crater area. The geometry of the clusters suggests a source region depicting the shallower feeding system. Overall, the results highlight that the high precision locations method is an efficient and quick tool to obtain a better understanding of the magmatic processes occurring during an ongoing eruption.
    Description: Published
    Description: 405-415
    Description: 1.4. TTC - Sorveglianza sismologica delle aree vulcaniche attive
    Description: JCR Journal
    Description: reserved
    Keywords: eruption ; high precision location ; seismic swarms ; magma dynamics ; 04. Solid Earth::04.06. Seismology::04.06.08. Volcano seismology
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  • 14
    Publication Date: 2017-04-04
    Description: The first comprehensive geochemical data-set of the fluids circulating over a 14,000 km2-wide seismicprone area of the Southern Apennines, Calabria Region (Italy), is presented here. The geochemical investigations were carried out with the twofold aim of constraining the origin and interactions of the circulating fluids and to investigate possible relationships with local faults. Sixty samples of both thermal and cold waters were collected, from which the dissolved gases were extracted. The geochemical features of the water samples display different types and degrees of water–rock interactions, irrespective of the outlet temperature. The calculated equilibrium temperatures of the thermal waters (60–160 C) and the low heat flow of thewhole study area, are consistent with a heating process due to deep water circulation and rapid upflow through lithospheric structures. The composition of the dissolved gases reveals that crustal-originating gases (N2 and CO2-dominated) feed all the groundwaters. The 3He/4He ratios of the dissolved He, in the range of 0.03–0.22Rac for the thermal waters and 0.05–0.63Rac for the cold waters (Rac = He isotope ratio corrected for atmospheric contamination), are mainly the result of a two-component (radiogenic and atmospheric) mixing, although indications of mantle-derived He are found in some cold waters. As the study area had been hit by 18 of the most destructive earthquakes (magnitude ranging from 5.9 to 7.2) occurring over a 280-a time span (1626–1908) in the Southern Apennines, the reported results on the circulating fluids may represent the reference for a better inside knowledge of the fault-fluid relationships and for the development of long-term geochemical monitoring strategies for the area.
    Description: Published
    Description: 540–554
    Description: 3.2. Tettonica attiva
    Description: JCR Journal
    Description: open
    Keywords: Fluids ; Geochemistry ; Faults ; Seismicity ; 04. Solid Earth::04.02. Exploration geophysics::04.02.01. Geochemical exploration
    Repository Name: Istituto Nazionale di Geofisica e Vulcanologia (INGV)
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  • 15
    Publication Date: 2017-04-04
    Description: The Miano borehole, 1047 m deep, is located close to the river Parma in the Northern Apennines, Italy. A measuring station has been installed to observe the discharge of fluids continuously since November 2004. The upwelling fluid of this artesian well is a mixture of thermal water and CH4 as main components. In non-seismogenic areas, a relatively constant fluid emission would be expected, perhaps overlaid with long term variations from that kind of deep reservoir over time. However, the continuous record of the fluid emission, in particular the water discharge, the gas flow rate and the water temperature, show periods of stable values interrupted by anomalous periods of fluctuations in the recorded parameters. The anomalous variations of these parameters are of low amplitude in comparison to the total values but significant in their long-term trend. Meteorological effects due to rain and barometric pressure were not detected in recorded data probably due to reservoir depth and relatively high reservoir overpressure. Influences due to the ambient temperature after the discharge were evaluated by statistical analysis. Our results suggest that recorded changes in fluid emission parameters can be interpreted as a mixing process of different fluid components at depth by variations in pore pressure as a result of seismogenic stress variation. Local seismicity was analyzed in comparison to the fluid physico-chemical data. The analysis supports the idea that an influence on fluid transport conditions due to geodynamic processes exists. Water temperature data show frequent anomalies probably connected with possible precursory phenomena of local seismic events.
    Description: Published
    Description: 555–571
    Description: 3.2. Tettonica attiva
    Description: JCR Journal
    Description: open
    Keywords: Fluids ; Seismicity ; 04. Solid Earth::04.02. Exploration geophysics::04.02.01. Geochemical exploration
    Repository Name: Istituto Nazionale di Geofisica e Vulcanologia (INGV)
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  • 16
    Publication Date: 2017-04-04
    Description: An integrated high-resolution magnetobiocyclostratigraphy including radioisotopic dating and astronomical tuning is presented for the interval between 15.29 and 14.17 Ma in the marine La Vedova section in northern Italy. The natural remanent magnetization is carried by the iron sulphide greigite and the resultant magnetostratigraphy can be correlated straightforwardly to the interval ranging from C5Bn.2n to C5ADn in the Astronomically Tuned Neogene Time Scale (ATNTS2004). Spectral analysis on high-resolution magnetic susceptibility and geochemical proxy records in the depth domain and, using our magnetobiostratigraphic age model, in the time domain demonstrate that the various scales of cyclicity in the section are related to astronomical climate forcing. Starting from our initial age model, larger-scale cycles were first tuned to eccentricity. This first-order tuning was followed by tuning the basic cycle to precession and boreal summer insolation using inferred phase relations between maxima in Ca/Al, redox-sensitive elements and Ba, and minima in magnetic susceptibility, and maxima in precession and minima in obliquity and boreal summer insolation. Our astronomical ages for reversal boundaries are supported by analysis of sea floor spreading rates and should replace the existing ages in the ATNTS2004 lacking direct astronomical control. Two major steps in the geochemical proxy records, astronomically dated at 15.074 and 14.489 Ma, coincide with abrupt changes in sedimentation rate, and are the result of the combined effect of the ∼400-kyr eccentricity cycle superimposed upon a longer-term climatic or tectonic induced trend.
    Description: Published
    Description: 254–269
    Description: 2.2. Laboratorio di paleomagnetismo
    Description: JCR Journal
    Description: restricted
    Keywords: Middle Miocene ; Langhian ; Mediterranean ; astronomical tuning ; palaeomagnetism ; biostratigraphy ; environmental changes ; orbital forcing ; 04. Solid Earth::04.04. Geology::04.04.10. Stratigraphy ; 04. Solid Earth::04.05. Geomagnetism::04.05.06. Paleomagnetism
    Repository Name: Istituto Nazionale di Geofisica e Vulcanologia (INGV)
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  • 17
    Publication Date: 2019-03-05
    Description: A three-dimensional S wave attenuation tomography of Mt. Vesuvius has been obtained with multiple measurements of coda-normalized S-wave spectra of local small magnitude earthquakes.We used 6609 waveforms, relative to 826 volcano-tectonic earthquakes, located close to the crater axis in a depth range between 1 and 4 km (below the sea level), recorded at seven 3-component digital seismic stations. We adopted a two-point ray-tracing; rays were traced in an high resolution 3-D velocity model. The spatial resolution achieved in the attenuation tomography is comparable with that of the velocity tomography (we resolve 300m side cubic cells). We statistically tested that the results are almost independent from the radiation pattern. We also applied an improvement of the ordinary spectral-slope method to both P- and S-waves, assuming that the differences between the theoretical and the experimental high frequency spectral-slope are only due to the attenuation effects. Consequently we could check the codanormalization method also comparing the S attenuation image with the P attenuation image. The images were obtained inverting the spectral data with a multiple resolution approach. Results have shown the general coincidence of low attenuation with high velocity zones. The joint interpretation of velocity and attenuation images allows us to interpret the low attenuation zone intruding toward the surface until a depth of 500m below the sea level as related to the residual part of solidified magma from the last eruption. In the depth range between −700 and −2300 images are consistent with the presence of multiple acquifer layers. No evidence of magma patches greater than the minimum cell dimension (300m) has been found. A shallow P wave attenuation anomaly (beneath the southern flank of the volcano) is consitent with the presence of gas saturated rocks. The zone characterized by the maximum seismic energy release cohincides with a high attenuation and low velocity volume, interpreted as a cracked medium.
    Description: Published
    Description: 17–32
    Description: 3.1. Fisica dei terremoti
    Description: JCR Journal
    Description: reserved
    Keywords: Attenuation tomography ; Mt. Vesuvius ; Coda normalization method ; Spectral slope ; Multi resolution inversion ; 04. Solid Earth::04.06. Seismology::04.06.07. Tomography and anisotropy ; 04. Solid Earth::04.06. Seismology::04.06.08. Volcano seismology ; 04. Solid Earth::04.06. Seismology::04.06.09. Waves and wave analysis
    Repository Name: Istituto Nazionale di Geofisica e Vulcanologia (INGV)
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  • 18
    Publication Date: 2020-02-24
    Description: We investigated the relationship between volcano-seismic events, recorded at La Fossa crater of Vulcano (Aeolian Islands, Italy) during 2004-2006, and the dynamics of the hydrothermal system. During the period of study, three episodes of increasing numbers of volcano-seismic events took place at the same time as geothermal and geochemical anomalies were observed. These geothermal and geochemical anomalies have been interpreted as resulting from an increasing deep magmatic component of the hydrothermal fluids. Three classes of seismic events (long period, high frequency and monochromatic events), characterised by different spectral content and various similarity of the waveforms, have been recognised. These events, clustered mainly below La Fossa crater area at depths of 0.5–1.1 km b.s.l., were space-distributed according to the classes. Based on their features, we can infer that such events at Vulcano are related to two different source mechanisms: (1) fracturing processes of rocks and (2) resonance of cracks (or conduits) filled with hydrothermal fluid. In the light of these source mechanisms, the increase in the number of events, at the same time as geochemical and geothermal anomalies were observed, was interpreted as the result of an increasing magmatic component of the hydrothermal fluids, implying an increase of their flux. Indeed, such variation caused an increase of both the pore pressure within the rocks of the volcanic system and the amount of ascending fluids. Increased pore pressures gave rise to fracturing processes, while the increased fluid flux favoured resonance and vibration processes in cracks and conduits. Finally, a gradual temporal variation of the waveform of the hybrid events (one of the subclasses of long period events) was observed, likely caused by heating and drying of the hydrothermal system.
    Description: Published
    Description: 803-816
    Description: 1.4. TTC - Sorveglianza sismologica delle aree vulcaniche attive
    Description: JCR Journal
    Description: reserved
    Keywords: Volcano seismology ; Vulcano Island ; 04. Solid Earth::04.06. Seismology::04.06.08. Volcano seismology
    Repository Name: Istituto Nazionale di Geofisica e Vulcanologia (INGV)
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  • 19
    Publication Date: 2017-04-04
    Description: A crucial point in the analysis of tectonic earthquakes occurring in a volcanic area is the inference of the orientation of the structures along which the ruptures occur. These structures represent zones of weakness which could favor the migration of melt toward the surface and the assessment of their geometry is a fundamental step toward efficient evaluation of volcanic risk. We analyzed a high-quality dataset of 171 lowmagnitude, tectonic earthquakes that occurred at Mt. Etna during the 2002–2003 eruption. We applied a recently developed technique aimed at inferring the source parameters (source size, dip and strike fault) and the intrinsic quality factor Qp of P waves from the inversion of rise times. The technique is based on numerically calibrated relationships among the rise time of first P waves and the source parameters for a circular crack rupturing at a constant velocity. For the most of the events the directivity source effect did not allow us to constrain the fault plane orientation. For a subset of 45 events with well constrained focal mechanisms we were able to constrain the “true” fault plane orientation. The level of resolution of the fault planes was assessed through a non linear analysis based on the random deviates technique. The significance of the retrieved fault plane solutions and the fit of the assumed source model to data were assessed through a χ-square test. Most of the retrieved fault plane solutions agree with the geometrical trend of known surface faults. The inferred source parameters and Qp are in agreement with the results of previous studies
    Description: Published
    Description: 247-256
    Description: 3.1. Fisica dei terremoti
    Description: JCR Journal
    Description: reserved
    Keywords: rise time ; directivity ; 04. Solid Earth::04.06. Seismology::04.06.08. Volcano seismology
    Repository Name: Istituto Nazionale di Geofisica e Vulcanologia (INGV)
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  • 20
    Publication Date: 2017-04-04
    Description: The Danian–Selandian (D–S) boundary has been identified for the first time in the Black Sea coast at Bjala (Bulgaria) based on a new integrated bio-, magneto- and cyclostratigraphic study. Several correlation criteria as established for the basal Selandian GSSP from Zumaia (Basque Basin) are evaluated. Noteworthy, is the almost complete lack of calcareous nannoplankton species Braarudosphaera bigelowi in the Bulgarian sections, a sharp decrease of which was indicated as suitable criteria for defining the D–S boundary as it occurred both at Zumaia and in the classical locations of the North Sea basin. Conversely, the second evolutionary radiation of the calcareous nannofossil genus Fasciculithus together with the occurrence of Fasciculithus tympaniformis that define the NP4/NP5 zonal boundary seem to be reliable criteria to approximate the D–S boundary. In detail, however, the best approach is to integrate biostratigraphic data within a magnetostratigraphic and/or cyclostratigraphic framework. Refinements on the placement of chron C27n at Zumaia and robust bed-by-bed correlation between several Basque sections and Bjala indicates that the D–S boundary is located 30 precession cycles (~630 ky) above C27n. In addition to the precession-related marl–limestone couplets and 100-ky eccentricity bundles recognized in the studied sections, expression of the stable 405-ky long eccentricity allows direct tuning to the astronomical solutions. A correlation of the land-based sections with previously tuned data from ODP Site1262 from the Southern Atlantic is challenged. Our choice is consistent with original tuning at Zumaia but shifts one 100-ky cycle older previous tuning from Site 1262 along the interval above C27n. Under the preferred tuning scheme the D–S boundary can be given an age of 61.641± 0.040 Ma on the La04 orbital solution.
    Description: Published
    Description: 511-533
    Description: 2.2. Laboratorio di paleomagnetismo
    Description: JCR Journal
    Description: restricted
    Keywords: Paleocene ; Magnetostratigraphy ; Orbital tuning ; Calcareous nannofossils ; Selandian GSSP ; 04. Solid Earth::04.04. Geology::04.04.08. Sediments: dating, processes, transport ; 04. Solid Earth::04.04. Geology::04.04.10. Stratigraphy ; 04. Solid Earth::04.05. Geomagnetism::04.05.06. Paleomagnetism
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  • 21
    Publication Date: 2017-04-04
    Description: The Fortuna Basin is an example of a marginal Mediterranean basin with evaporitic sedimentation during the Late Tortonian and Messinian. This basin shows an early restriction event before the main Messinian Salinity Crisis (MSC) that allows the Tortonian Salinity Crisis (TSC) to be proposed as a tectonic uplift event isolating the eastern Betic basins. Four evaporitic events are present in the central part of the Fortuna Basin, from bottom to top: Los Baños Marls Formation (composed by Fenazar Conglomerate Bed, Lower Gypsum Member [Mb] and Sanel Mb), Tale Gypsum Formation (Fm), Chicamo Diatomites and Gypsum Cycles Fm, and Rambla Salada Gypsum Fm. The present work documents the first biostratigraphic dating based on calcareous nannoplankton of these events. The lowest occurrence (LO) of Amaurolithus primus is registered at the upper part of the Sanel Mb, below the Tale Gypsum Fm. The LOs of Amaurolithus delicatus and Reticulofenestra rotaria, which mark the base of the Messinian, occur in the lower part of the Chicamo Cycles Fm, above the Tale Gypsum Fm, the Triquetrorhabdulus rugosus-Nicklithus amplificus integrate form and the LO of Nicklithus cf. amplificus in the upper part of the Chicamo Cycles Fm. Taking into account these results, a new calibration of the available magnetostratigraphic data is presented: the Chicamo Cycles Fm were formed during the reverse chron C3Ar and the Tortonian-Messinian boundary should be found within the Tale Gypsum Fm or near the top of the Sanel Mb. The onset of the TSC, the first restriction phase of the Fortuna Basin, is represented by the Fenazar Conglomerate Bed, bottom of the Los Baños Fm, and not by the Tale Gypsum Fm, as previously considered.
    Description: Published
    Description: 201-217
    Description: 2.2. Laboratorio di paleomagnetismo
    Description: JCR Journal
    Description: restricted
    Keywords: Betic Cordillera ; Tortonian Salinity Crisis ; Calcareous nannoplankton ; Messinian ; Fortuna Basin ; 04. Solid Earth::04.04. Geology::04.04.08. Sediments: dating, processes, transport ; 04. Solid Earth::04.04. Geology::04.04.10. Stratigraphy ; 04. Solid Earth::04.05. Geomagnetism::04.05.06. Paleomagnetism
    Repository Name: Istituto Nazionale di Geofisica e Vulcanologia (INGV)
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  • 22
    Publication Date: 2017-04-04
    Description: The Pleistocene history of climate control on sedimentation in the Southern Alps-Po Plain system, northern Italy, was reconstructed using an integrated magnetostratigraphic, palynological, and petrographical approach on a 47-m-deep core. The core mainly consists of lacustrine sediments pertaining to the Bagaggera sequence, deposited at the foothills of the Southern Alps during the late Matuyama subchron (0.99-0.78 Ma). At that time, climate worsened globally and locally it caused the progradation of an alluvial fan unit onto the nearby Po Plain, triggering lake formation by damming of a tributary valley. These new data are used in conjunction with data from the literature to highlight and track the effects of climate forcing on sedimentation during the late Matuyama subchron in different orographic and geodynamic settings of the Southern Alps-Po Plain system as part of the greater Alpine area. We found that the episodes of alluvial fan and braidplam progradation observed in the southern foreland of the Alps during the late Matuyama global cooling seem broadly synchronous with the deposition of most of the so-called Gunz and Alterer Deckenschotter deposits in the northern forelands of the Alps as well as with the first major waxing of the Alpine valley glaciers, possibly around the Marine Isotope Stage 22 (~0.87 Ma).
    Description: Regione Lombardia, IREALP
    Description: Published
    Description: 832–846
    Description: 3.2. Tettonica attiva
    Description: JCR Journal
    Description: restricted
    Keywords: Paleomagnetism ; Climate Change ; Early Pleistocene ; Italy ; Stratigraphy ; Petrography ; Palynology ; 03. Hydrosphere::03.01. General::03.01.03. Global climate models ; 04. Solid Earth::04.04. Geology::04.04.02. Geochronology ; 04. Solid Earth::04.04. Geology::04.04.03. Geomorphology ; 04. Solid Earth::04.04. Geology::04.04.08. Sediments: dating, processes, transport ; 04. Solid Earth::04.04. Geology::04.04.10. Stratigraphy ; 04. Solid Earth::04.05. Geomagnetism::04.05.06. Paleomagnetism
    Repository Name: Istituto Nazionale di Geofisica e Vulcanologia (INGV)
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  • 23
    Publication Date: 2017-04-04
    Description: A critical assessment of the available magnetostratigraphic and/or radiometric age constraints on key sites bearing hominin remains and/or lithic industries from southern Europe (Italy, France, Spain) leads us to propose that the main window of early hominin presence in southern Europe is broadly comprised between the Jaramillo subchron and the Brunhes–Matuyama boundary (i.e., subchron C1r.1r, 0.99–0.78 Ma). Within the dating uncertainties, this ~200 ky time window broadly coincides with the late Early Pleistocene global climate transition that contains marine isotope stage (MIS) 22 (~0.87Ma), the first prominent cold stage of the Pleistocene. We suggest that aridification in North Africa and Eastern Europe, particularly harsh during MIS22 times, triggered migration pulses of large herbivores, particularly elephants, from these regions into southern European refugia, and that hominins migrated with them. Finally, we speculate on common pathways of late Early Pleistocene dispersal of elephants and hominins from their home in savannah Africa to southern Europe, elephant and hominin buen retiro. In particular, we stress the importance of the Po Valley of northern Italy that became largely and permanently exposed only since MIS22, thus allowing possibly for the first time in the Pleistocene viable new migration routes for large mammals and hominins across northern Italy to southern France and Spain in the west.
    Description: Published
    Description: 79-93
    Description: 3.2. Tettonica attiva
    Description: JCR Journal
    Description: restricted
    Keywords: Pleistocene ; Magnetostratigraphy ; Hominins ; Migration ; Europe ; Galerian ; Jaramillo ; Brunhes-Matuyama ; 04. Solid Earth::04.04. Geology::04.04.02. Geochronology ; 04. Solid Earth::04.04. Geology::04.04.08. Sediments: dating, processes, transport ; 04. Solid Earth::04.04. Geology::04.04.10. Stratigraphy ; 04. Solid Earth::04.05. Geomagnetism::04.05.06. Paleomagnetism
    Repository Name: Istituto Nazionale di Geofisica e Vulcanologia (INGV)
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  • 24
    Publication Date: 2017-04-04
    Description: Aim of this paper is to identify variations in Very-Long-Period (VLP) source associated with eruptive style changes at Stromboli volcano (Italy) and to retrieve information about the shallow plumbing system that sustains the eruptive activity. We have considered a dataset of 74493 VLP events recorded during the period from January through August 2007, when an effusive eruption occurred (February 27–April 2).We performed a polarization analysis of the entire dataset and divided the considered period into four sub-periods on the basis of polarization characteristics. We then located the events and selected a subset of these events by applying a location quality threshold. The high quality locations demonstrate that during the effusive eruption the VLP sources first moved downward and then moved southwestward. To retrieve information about the geometry of the structures where the source processes take place, we further consider a subset of events and estimate their source mechanisms by using a moment tensor source function (MTSF) inversion technique. Inversion of the waveforms of the VLP events that occurred on February 27 allows us to obtain information about the dynamics of different source centroids distributed along different portions of the shallow magmatic conduits. The structure defined by the locations and source mechanisms shows a greater complexity compared with previous studies and their time variations give an insight into the kinematics of the eruption.
    Description: Published
    Description: 162–171
    Description: 1.4. TTC - Sorveglianza sismologica delle aree vulcaniche attive
    Description: JCR Journal
    Description: reserved
    Keywords: stromboli ; very-long-period events ; seismic source mechanism ; volcano seismology ; 04. Solid Earth::04.06. Seismology::04.06.08. Volcano seismology ; 04. Solid Earth::04.08. Volcanology::04.08.06. Volcano monitoring
    Repository Name: Istituto Nazionale di Geofisica e Vulcanologia (INGV)
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  • 25
    Electronic Resource
    Electronic Resource
    Springer
    Pure and applied geophysics 122 (1984), S. 492-530 
    ISSN: 1420-9136
    Keywords: Lithosphere ; Fluids ; Earthquakes ; Fracture
    Source: Springer Online Journal Archives 1860-2000
    Topics: Geosciences , Physics
    Notes: Abstract The Earth is continuously expelling gases and liquids from great depths—juvenile volatiles from the mantle and recycled metamorphic products. Some of these fluids ascend through liquid rock in volcanic processes, but others utilize fractures and faults as conduits through the solid lithosphere. The latter process may have a major influence on earthquakes, since fluids at near lithostatic pressures appear to be required to activate deep faults that would otherwise remain locked. Fluids can be driven upward through solid rock by buoyancy, but only if present in sufficient concentration to form large-scale domains occupying interconnected fracture porosity. A growing fluid domain becomes so mobilized only when it attains the critical vertical dimension required for hydrostatic instability. This dimension, depending on the ultimate compressive yield strength of the rock, may be as much as several kilometers. Any column of fluid ascending through fractures in the solid lithosphere from a prolific deep source must become organized into a vertical sequence of discrete domains, separated by fluid-pressure discontinuities. This is required because a continuous hydrostatic-fluid-pressure profile extending from an arbitrarily deep source to the surface cannot be permitted by the finite strength of rock. A vertically stacked sequence of domains allows the internal fluid-pressure profile to approximate the external rock-stress profile in a stepwise fashion. The pressure discontinuity below the base of the uppermost hydrostatic domain may be responsible for some occurrences of so-called anomalous geopressures. An ascending stream of fluid that percolates upward from a deep source through a column of domains must encounter a sequence of abrupt pressure decreases at the transitions between successive domains. If supercritical gases act as solvents, the dissolved substances may drop out of solution at such pressure discontinuities, resulting in a local concentration of minerals and other substances. At great depths, brittle fracture would normally be prevented by high pressure and temperature, with all excessive stress discharged by ductile flow. Rock strata invaded by an ascending fluid domain are weakened, however, because cracks generated or reactivated by the high-pressure fluid can support the overburden, greatly reducing internal friction. This reduction of strength may cause a previously stressed rock to fail, resulting in hydraulic shear fracture. Thus, earthquakes may be triggered by the buoyant migration of deep-source fluids. The actual timing of the failure that leads to such an earthquake may be determined by the relatively rapid inflation of a fluid domain and not by any significant increase in the probably much slower rate of regional tectonic strain. Many earthquake precursory phenomena may be secondary symptoms of an increase in pore-fluid pressure, and certain coseismic phenomena may result from the venting of high-pressure fluids when faults break the surface. Instabilities in the migration of such fluid domains may also contribute to or cause the eruption of mud volcanoes, magma volcanoes, and kimberlite pipes.
    Type of Medium: Electronic Resource
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  • 26
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    Unknown
    Elsevier
    In:  Amsterdam, Elsevier, vol. 14 B, pp. 225, (ISBN 3-7643-7011-4)
    Publication Date: 1984
    Keywords: Applied geophysics ; seismic Migration ; Seismics (controlled source seismology) ; Acoustics
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  • 27
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    Unknown
    Elsevier
    In:  Amsterdam, Elsevier, vol. Developments in Petroleum Science vol. 15A, no. Publ. No. 12, pp. 9, (ISBN: 0-12-636380-3)
    Publication Date: 1984
    Keywords: Borehole geophys. ; Textbook of geophysics ; GFZ ; RUB ; GMG ; 3.45.8 ; UniL ; IfGuG ; in ; Französisch
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  • 28
    facet.materialart.
    Unknown
    Elsevier
    In:  Amsterdam, Elsevier, vol. 81A and 81B, no. 22, pp. 65-70, (1405101733, 336 p.)
    Publication Date: 1984
    Keywords: Textbook of geophysics ; Earth model, also for more shallow analyses !
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  • 29
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    Unknown
    American Association for the Advancement of Science (AAAS)
    Publication Date: 2010-08-14
    Description: 〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Bascompte, Jordi -- New York, N.Y. -- Science. 2010 Aug 13;329(5993):765-6. doi: 10.1126/science.1194255.〈br /〉〈span class="detail_caption"〉Author address: 〈/span〉Integrative Ecology Group, Estacion Biologica de Donana, Consejo Superior de Investigaciones Cientificas, Americo Vespucio s/n, E-41092 Sevilla, Spain. bascompte@ebd.csic.es〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/20705836" target="_blank"〉PubMed〈/a〉
    Keywords: Animals ; *Ecosystem ; Food Chain ; Insects/*physiology ; Models, Biological ; *Plant Physiological Phenomena ; Pollination ; *Symbiosis
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
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  • 30
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    Unknown
    American Association for the Advancement of Science (AAAS)
    Publication Date: 2010-03-06
    Description: 〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Clutton-Brock, Tim -- Sheldon, Ben C -- New York, N.Y. -- Science. 2010 Mar 5;327(5970):1207-8. doi: 10.1126/science.1187796.〈br /〉〈span class="detail_caption"〉Author address: 〈/span〉Department of Zoology, University of Cambridge, Cambridge CB2 3EJ, UK. thcb@cam.ac.uk〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/20203037" target="_blank"〉PubMed〈/a〉
    Keywords: Animals ; *Behavior, Animal ; *Ecosystem ; Female ; Interdisciplinary Communication ; Male ; *Mammals/physiology ; Pan troglodytes/physiology ; *Primates/physiology ; Reproduction ; *Research ; Research Support as Topic ; Time Factors
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
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  • 31
    Publication Date: 2010-01-02
    Description: Meiotic recombination events cluster into narrow segments of the genome, defined as hotspots. Here, we demonstrate that a major player for hotspot specification is the Prdm9 gene. First, two mouse strains that differ in hotspot usage are polymorphic for the zinc finger DNA binding array of PRDM9. Second, the human consensus PRDM9 allele is predicted to recognize the 13-mer motif enriched at human hotspots; this DNA binding specificity is verified by in vitro studies. Third, allelic variants of PRDM9 zinc fingers are significantly associated with variability in genome-wide hotspot usage among humans. Our results provide a molecular basis for the distribution of meiotic recombination in mammals, in which the binding of PRDM9 to specific DNA sequences targets the initiation of recombination at specific locations in the genome.〈br /〉〈br /〉〈a href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4295902/" target="_blank"〉〈img src="https://static.pubmed.gov/portal/portal3rc.fcgi/4089621/img/3977009" border="0"〉〈/a〉   〈a href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4295902/" target="_blank"〉This paper as free author manuscript - peer-reviewed and accepted for publication〈/a〉〈br /〉〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Baudat, F -- Buard, J -- Grey, C -- Fledel-Alon, A -- Ober, C -- Przeworski, M -- Coop, G -- de Massy, B -- 03S1/PHS HHS/ -- GM83098/GM/NIGMS NIH HHS/ -- HD21244/HD/NICHD NIH HHS/ -- HL085197/HL/NHLBI NIH HHS/ -- R01 GM083098/GM/NIGMS NIH HHS/ -- R01 HD021244/HD/NICHD NIH HHS/ -- R01 HL085197/HL/NHLBI NIH HHS/ -- Howard Hughes Medical Institute/ -- New York, N.Y. -- Science. 2010 Feb 12;327(5967):836-40. doi: 10.1126/science.1183439. Epub 2009 Dec 31.〈br /〉〈span class="detail_caption"〉Author address: 〈/span〉Institut de Genetique Humaine, UPR1142, CNRS, Montpellier, France.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/20044539" target="_blank"〉PubMed〈/a〉
    Keywords: Alleles ; Amino Acid Sequence ; Animals ; Base Sequence ; Binding Sites ; DNA/chemistry/metabolism ; DNA Breaks, Double-Stranded ; DNA-Binding Proteins/chemistry/genetics/metabolism ; Genome ; Genome, Human ; Genotype ; Histone-Lysine N-Methyltransferase/chemistry/*genetics/*metabolism ; Humans ; Meiosis/*genetics ; Mice ; Mice, Inbred C57BL ; Molecular Sequence Data ; Phenotype ; *Recombination, Genetic ; Zinc Fingers/genetics
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  • 32
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    American Association for the Advancement of Science (AAAS)
    Publication Date: 2010-01-23
    Description: Forests both take up CO2 and enhance absorption of solar radiation, with contrasting effects on global temperature. Based on a 9-year study in the forests' dry timberline, we show that substantial carbon sequestration (cooling effect) is maintained in the large dry transition zone (precipitation from 200 to 600 millimeters) by shifts in peak photosynthetic activities from summer to early spring, and this is counteracted by longwave radiation (L) suppression (warming effect), doubling the forestation shortwave (S) albedo effect. Several decades of carbon accumulation are required to balance the twofold S + L effect. Desertification over the past several decades, however, contributed negative forcing at Earth's surface equivalent to approximately 20% of the global anthropogenic CO2 effect over the same period, moderating warming trends.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Rotenberg, Eyal -- Yakir, Dan -- New York, N.Y. -- Science. 2010 Jan 22;327(5964):451-4. doi: 10.1126/science.1179998.〈br /〉〈span class="detail_caption"〉Author address: 〈/span〉Environmental Sciences and Energy Research, Weizmann Institute of Science, Rehovot 76100, Israel.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/20093470" target="_blank"〉PubMed〈/a〉
    Keywords: Carbon/*metabolism ; Carbon Dioxide/metabolism ; *Climatic Processes ; Conservation of Natural Resources ; *Ecosystem ; Geography ; Israel ; Photosynthesis ; Seasons ; Temperature ; *Trees/growth & development/metabolism
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  • 33
    Publication Date: 2010-03-20
    Description: 〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Bawa, Kamaljit S -- Koh, Lian Pin -- Lee, Tien Ming -- Liu, Jianguo -- Ramakrishnan, P S -- Yu, Douglas W -- Zhang, Ya-ping -- Raven, Peter H -- New York, N.Y. -- Science. 2010 Mar 19;327(5972):1457, 1459. doi: 10.1126/science.1185164.〈br /〉〈span class="detail_caption"〉Author address: 〈/span〉University of Massachusetts, Boston, MA 02125, USA.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/20299578" target="_blank"〉PubMed〈/a〉
    Keywords: Biodiversity ; China ; *Climate Change ; *Conservation of Natural Resources ; *Ecosystem ; *Environment ; India ; *International Cooperation ; Politics ; Trees ; Water
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  • 34
    Publication Date: 2010-10-23
    Description: CD4(+)Foxp3(+) regulatory T (T(reg)) cells are important for maintaining immune tolerance. Understanding the molecular mechanism that regulates T(reg) differentiation will facilitate the development of effective therapeutic strategies against autoimmune diseases. We report here that the SUMO E3 ligase PIAS1 restricts the differentiation of natural T(reg) cells by maintaining a repressive chromatin state of the Foxp3 promoter. PIAS1 acts by binding to the Foxp3 promoter to recruit DNA methyltransferases and heterochromatin protein 1 for epigenetic modifications. Pias1 deletion caused promoter demethylation, reduced histone H3 methylation at Lys(9), and enhanced promoter accessibility. Consistently, Pias1(-/-) mice displayed an increased natural T(reg) cell population and were resistant to the development of experimental autoimmune encephalomyelitis. Our studies have identified an epigenetic mechanism that negatively regulates the differentiation of natural T(reg) cells.〈br /〉〈br /〉〈a href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3043201/" target="_blank"〉〈img src="https://static.pubmed.gov/portal/portal3rc.fcgi/4089621/img/3977009" border="0"〉〈/a〉   〈a href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3043201/" target="_blank"〉This paper as free author manuscript - peer-reviewed and accepted for publication〈/a〉〈br /〉〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Liu, Bin -- Tahk, Samuel -- Yee, Kathleen M -- Fan, Guoping -- Shuai, Ke -- K01 AR52717-01/AR/NIAMS NIH HHS/ -- R01 AI063286/AI/NIAID NIH HHS/ -- R01 AI063286-05/AI/NIAID NIH HHS/ -- R01 GM085797/GM/NIGMS NIH HHS/ -- R01 GM085797-03/GM/NIGMS NIH HHS/ -- R01AI063286/AI/NIAID NIH HHS/ -- R01GM085797/GM/NIGMS NIH HHS/ -- New York, N.Y. -- Science. 2010 Oct 22;330(6003):521-5. doi: 10.1126/science.1193787.〈br /〉〈span class="detail_caption"〉Author address: 〈/span〉Division of Hematology-Oncology, Department of Medicine, 11-934 Factor Building, 10833 Le Conte Avenue, University of California, Los Angeles, Los Angeles, CA 90095, USA. bliu@ucla.edu〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/20966256" target="_blank"〉PubMed〈/a〉
    Keywords: Animals ; Binding Sites ; CD4-Positive T-Lymphocytes/cytology ; Chromatin/metabolism ; DNA (Cytosine-5-)-Methyltransferase/metabolism ; DNA Methylation ; Encephalomyelitis, Autoimmune, Experimental/immunology ; *Epigenesis, Genetic ; Female ; Forkhead Transcription Factors/genetics ; Histones/metabolism ; Lymphopoiesis/*genetics ; Male ; Mice ; Mice, Inbred C57BL ; Mice, Inbred Strains ; Promoter Regions, Genetic ; Protein Inhibitors of Activated STAT/*physiology ; Repressor Proteins/*physiology ; T-Lymphocytes, Regulatory/*cytology/immunology ; Ubiquitin-Protein Ligases/*physiology
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  • 35
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    American Association for the Advancement of Science (AAAS)
    Publication Date: 2010-06-19
    Description: 〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Kaiser, Jocelyn -- New York, N.Y. -- Science. 2010 Jun 18;328(5985):1506. doi: 10.1126/science.328.5985.1506.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/20558704" target="_blank"〉PubMed〈/a〉
    Keywords: Animals ; Atlantic Ocean ; *Ecosystem ; Pacific Ocean ; Particle Size ; Particulate Matter ; *Plastics/toxicity ; *Seawater ; Water Movements ; *Water Pollution ; Zooplankton
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  • 36
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    American Association for the Advancement of Science (AAAS)
    Publication Date: 2010-05-22
    Description: 〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Levy, Emmanuel D -- Landry, Christian R -- Michnick, Stephen W -- New York, N.Y. -- Science. 2010 May 21;328(5981):983-4. doi: 10.1126/science.1190993.〈br /〉〈span class="detail_caption"〉Author address: 〈/span〉Departement de Biochimie, Universite de Montreal, Montreal, Quebec, Canada H3T 1J4.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/20489011" target="_blank"〉PubMed〈/a〉
    Keywords: Binding Sites ; Mass Spectrometry ; Metabolic Networks and Pathways ; Models, Biological ; Phosphoprotein Phosphatases/*metabolism ; Phosphorylation ; Protein Interaction Mapping ; Protein Kinases/*metabolism ; Saccharomyces cerevisiae/enzymology/*metabolism ; Saccharomyces cerevisiae Proteins/*metabolism ; *Signal Transduction
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  • 37
    Publication Date: 2010-10-16
    Description: Food chain length (FCL) is a fundamental component of food web structure. Studies in a variety of ecosystems suggest that FCL is determined by energy supply, environmental stability, and/or ecosystem size, but the nature of the relationship between environmental stability and FCL, and the mechanism linking ecosystem size to FCL, remain unclear. Here we show that FCL increases with drainage area and decreases with hydrologic variability and intermittency across 36 North American rivers. Our analysis further suggests that hydrologic variability is the mechanism underlying the correlation between ecosystem size and FCL in rivers. Ecosystem size lengthens river food chains by integrating and attenuating discharge variation through stream networks, thereby enhancing environmental stability in larger river systems.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Sabo, John L -- Finlay, Jacques C -- Kennedy, Theodore -- Post, David M -- New York, N.Y. -- Science. 2010 Nov 12;330(6006):965-7. doi: 10.1126/science.1196005. Epub 2010 Oct 14.〈br /〉〈span class="detail_caption"〉Author address: 〈/span〉Faculty of Ecology, Evolution, and Environmental Sciences, School of Life Sciences, Arizona State University, Post Office Box 874501, Tempe, AZ 85287-4501, USA. John.L.Sabo@asu.edu〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/20947729" target="_blank"〉PubMed〈/a〉
    Keywords: Animals ; *Ecosystem ; Environment ; Fishes ; *Food Chain ; Invertebrates ; North America ; *Rivers ; Water Cycle ; Water Movements
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  • 38
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    American Association for the Advancement of Science (AAAS)
    Publication Date: 2010-03-27
    Description: 〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Normile, Dennis -- New York, N.Y. -- Science. 2010 Mar 26;327(5973):1568-70. doi: 10.1126/science.327.5973.1568.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/20339043" target="_blank"〉PubMed〈/a〉
    Keywords: Animals ; *Ecosystem ; *Environment ; Financing, Government ; Republic of Korea ; *Rivers ; Water Movements ; *Wetlands
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  • 39
    Publication Date: 2010-08-07
    Description: The class Ib ribonucleotide reductase of Escherichia coli can initiate reduction of nucleotides to deoxynucleotides with either a Mn(III)2-tyrosyl radical (Y*) or a Fe(III)2-Y* cofactor in the NrdF subunit. Whereas Fe(III)2-Y* can self-assemble from Fe(II)2-NrdF and O2, activation of Mn(II)2-NrdF requires a reduced flavoprotein, NrdI, proposed to form the oxidant for cofactor assembly by reduction of O2. The crystal structures reported here of E. coli Mn(II)2-NrdF and Fe(II)2-NrdF reveal different coordination environments, suggesting distinct initial binding sites for the oxidants during cofactor activation. In the structures of Mn(II)2-NrdF in complex with reduced and oxidized NrdI, a continuous channel connects the NrdI flavin cofactor to the NrdF Mn(II)2 active site. Crystallographic detection of a putative peroxide in this channel supports the proposed mechanism of Mn(III)2-Y* cofactor assembly.〈br /〉〈br /〉〈a href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3020666/" target="_blank"〉〈img src="https://static.pubmed.gov/portal/portal3rc.fcgi/4089621/img/3977009" border="0"〉〈/a〉   〈a href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3020666/" target="_blank"〉This paper as free author manuscript - peer-reviewed and accepted for publication〈/a〉〈br /〉〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Boal, Amie K -- Cotruvo, Joseph A Jr -- Stubbe, JoAnne -- Rosenzweig, Amy C -- GM58518/GM/NIGMS NIH HHS/ -- GM81393/GM/NIGMS NIH HHS/ -- R01 GM058518/GM/NIGMS NIH HHS/ -- R01 GM058518-13/GM/NIGMS NIH HHS/ -- Y1-CO-1020/CO/NCI NIH HHS/ -- Y1-GM-1104/GM/NIGMS NIH HHS/ -- New York, N.Y. -- Science. 2010 Sep 17;329(5998):1526-30. doi: 10.1126/science.1190187. Epub 2010 Aug 5.〈br /〉〈span class="detail_caption"〉Author address: 〈/span〉Department of Biochemistry, Molecular Biology and Cell Biology, Northwestern University, Evanston, IL 60208, USA.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/20688982" target="_blank"〉PubMed〈/a〉
    Keywords: Binding Sites ; Catalytic Domain ; Coenzymes/chemistry/metabolism ; Crystallography, X-Ray ; Enzyme Activation ; Escherichia coli/*enzymology ; Escherichia coli Proteins/*chemistry/*metabolism ; Ferrous Compounds/chemistry/metabolism ; Flavin Mononucleotide/chemistry/metabolism ; Flavodoxin/*chemistry/metabolism ; Hydrogen Bonding ; Ligands ; Manganese/*chemistry/metabolism ; Models, Molecular ; Oxidants/chemistry/metabolism ; Oxidation-Reduction ; Oxygen/chemistry/metabolism ; Peroxides/chemistry/metabolism ; Protein Folding ; Protein Multimerization ; Protein Subunits/chemistry/metabolism ; Ribonucleotide Reductases/*chemistry/*metabolism
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  • 40
    Publication Date: 2010-10-23
    Description: The biosphere is the major source and sink of nonmethane volatile organic compounds (VOCs) in the atmosphere. Gas-phase chemical reactions initiate the removal of these compounds from the atmosphere, which ultimately proceeds via deposition at the surface or direct oxidation to carbon monoxide or carbon dioxide. We performed ecosystem-scale flux measurements that show that the removal of oxygenated VOC via dry deposition is substantially larger than is currently assumed for deciduous ecosystems. Laboratory experiments indicate efficient enzymatic conversion and potential up-regulation of various stress-related genes, leading to enhanced uptake rates as a response to ozone and methyl vinyl ketone exposure or mechanical wounding. A revised scheme for the uptake of oxygenated VOCs, incorporated into a global chemistry-transport model, predicts appreciable regional changes in annual dry deposition fluxes.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Karl, T -- Harley, P -- Emmons, L -- Thornton, B -- Guenther, A -- Basu, C -- Turnipseed, A -- Jardine, K -- New York, N.Y. -- Science. 2010 Nov 5;330(6005):816-9. doi: 10.1126/science.1192534. Epub 2010 Oct 21.〈br /〉〈span class="detail_caption"〉Author address: 〈/span〉National Center for Atmospheric Research, Boulder, CO 80301, USA. tomkarl@ucar.edu〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/20966216" target="_blank"〉PubMed〈/a〉
    Keywords: Atmosphere/*chemistry ; *Ecosystem ; Gene Expression Regulation, Plant ; Oxidation-Reduction ; Plant Leaves/*metabolism ; Plants/genetics/*metabolism ; Populus/genetics/metabolism ; Stress, Physiological ; Trees/*metabolism ; Tropical Climate ; Up-Regulation ; Volatile Organic Compounds/*analysis/*metabolism
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  • 41
    Publication Date: 2010-02-27
    Description: Transcriptional positive-feedback loops are widely associated with bistability, characterized by two stable expression states that allow cells to respond to analog signals in a digital manner. Using a synthetic system in budding yeast, we show that positive feedback involving a promoter with multiple transcription factor (TF) binding sites can induce a steady-state bimodal response without cooperative binding of the TF. Deterministic models of this system do not predict bistability. Rather, the bimodal response requires a short-lived TF and stochastic fluctuations in the TF's expression. Multiple binding sites provide these fluctuations. Because many promoters possess multiple binding sites and many TFs are unstable, positive-feedback loops in gene regulatory networks may exhibit bimodal responses, but not necessarily because of deterministic bistability, as is commonly thought.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉To, Tsz-Leung -- Maheshri, Narendra -- New York, N.Y. -- Science. 2010 Feb 26;327(5969):1142-5. doi: 10.1126/science.1178962.〈br /〉〈span class="detail_caption"〉Author address: 〈/span〉Department of Chemical Engineering, Massachusetts Institute of Technology, Cambridge, MA 02139, USA.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/20185727" target="_blank"〉PubMed〈/a〉
    Keywords: Active Transport, Cell Nucleus ; Binding Sites ; Cell Nucleus/metabolism ; Doxycycline/metabolism ; Feedback, Physiological ; *Gene Expression Regulation, Fungal ; *Gene Regulatory Networks ; Models, Genetic ; Models, Statistical ; Promoter Regions, Genetic ; Protein Stability ; Recombinant Fusion Proteins/metabolism ; Saccharomyces cerevisiae/*genetics/metabolism ; Saccharomyces cerevisiae Proteins/chemistry/genetics/metabolism ; Stochastic Processes ; Transcription Factors/chemistry/genetics/*metabolism ; *Transcription, Genetic
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  • 42
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    American Association for the Advancement of Science (AAAS)
    Publication Date: 2010-02-20
    Description: 〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Schulze, E Detlef -- Schulze, Inge -- New York, N.Y. -- Science. 2010 Feb 19;327(5968):957. doi: 10.1126/science.327.5968.957-a.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/20167771" target="_blank"〉PubMed〈/a〉
    Keywords: Animals ; Biodiversity ; Climate Change ; *Conservation of Natural Resources/economics ; *Ecosystem ; *Forestry/economics ; Germany ; *Trees/growth & development ; Wood
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  • 43
    Publication Date: 2010-03-20
    Description: Differences in gene expression may play a major role in speciation and phenotypic diversity. We examined genome-wide differences in transcription factor (TF) binding in several humans and a single chimpanzee by using chromatin immunoprecipitation followed by sequencing. The binding sites of RNA polymerase II (PolII) and a key regulator of immune responses, nuclear factor kappaB (p65), were mapped in 10 lymphoblastoid cell lines, and 25 and 7.5% of the respective binding regions were found to differ between individuals. Binding differences were frequently associated with single-nucleotide polymorphisms and genomic structural variants, and these differences were often correlated with differences in gene expression, suggesting functional consequences of binding variation. Furthermore, comparing PolII binding between humans and chimpanzee suggests extensive divergence in TF binding. Our results indicate that many differences in individuals and species occur at the level of TF binding, and they provide insight into the genetic events responsible for these differences.〈br /〉〈br /〉〈a href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2938768/" target="_blank"〉〈img src="https://static.pubmed.gov/portal/portal3rc.fcgi/4089621/img/3977009" border="0"〉〈/a〉   〈a href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2938768/" target="_blank"〉This paper as free author manuscript - peer-reviewed and accepted for publication〈/a〉〈br /〉〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Kasowski, Maya -- Grubert, Fabian -- Heffelfinger, Christopher -- Hariharan, Manoj -- Asabere, Akwasi -- Waszak, Sebastian M -- Habegger, Lukas -- Rozowsky, Joel -- Shi, Minyi -- Urban, Alexander E -- Hong, Mi-Young -- Karczewski, Konrad J -- Huber, Wolfgang -- Weissman, Sherman M -- Gerstein, Mark B -- Korbel, Jan O -- Snyder, Michael -- R01 CA077808/CA/NCI NIH HHS/ -- R01 CA077808-09/CA/NCI NIH HHS/ -- T32 GM007205/GM/NIGMS NIH HHS/ -- T32 GM007205-34/GM/NIGMS NIH HHS/ -- T32GM07205/GM/NIGMS NIH HHS/ -- U54 HG004558/HG/NHGRI NIH HHS/ -- U54 HG004558-04/HG/NHGRI NIH HHS/ -- Howard Hughes Medical Institute/ -- New York, N.Y. -- Science. 2010 Apr 9;328(5975):232-5. doi: 10.1126/science.1183621. Epub 2010 Mar 18.〈br /〉〈span class="detail_caption"〉Author address: 〈/span〉Department of Molecular, Cellular, and Developmental Biology, Yale University, New Haven, CT 06520, USA.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/20299548" target="_blank"〉PubMed〈/a〉
    Keywords: Animals ; Binding Sites ; Cell Line ; Chromatin Immunoprecipitation ; DNA Copy Number Variations ; DNA, Intergenic ; Female ; *Gene Expression Regulation ; Humans ; Male ; Pan troglodytes/genetics ; *Polymorphism, Single Nucleotide ; Protein Binding ; RNA Polymerase II/genetics/*metabolism ; Sequence Analysis, DNA ; Species Specificity ; Transcription Factor RelA/genetics/*metabolism ; Transcription Initiation Site
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  • 44
    Publication Date: 2010-01-16
    Description: Integrins mediate cell adhesion to the extracellular matrix and transmit signals within the cell that stimulate cell spreading, retraction, migration, and proliferation. The mechanism of integrin outside-in signaling has been unclear. We found that the heterotrimeric guanine nucleotide-binding protein (G protein) Galpha13 directly bound to the integrin beta3 cytoplasmic domain and that Galpha13-integrin interaction was promoted by ligand binding to the integrin alphaIIbbeta3 and by guanosine triphosphate (GTP) loading of Galpha13. Interference of Galpha13 expression or a myristoylated fragment of Galpha13 that inhibited interaction of alphaIIbbeta3 with Galpha13 diminished activation of protein kinase c-Src and stimulated the small guanosine triphosphatase RhoA, consequently inhibiting cell spreading and accelerating cell retraction. We conclude that integrins are noncanonical Galpha13-coupled receptors that provide a mechanism for dynamic regulation of RhoA.〈br /〉〈br /〉〈a href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2842917/" target="_blank"〉〈img src="https://static.pubmed.gov/portal/portal3rc.fcgi/4089621/img/3977009" border="0"〉〈/a〉   〈a href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2842917/" target="_blank"〉This paper as free author manuscript - peer-reviewed and accepted for publication〈/a〉〈br /〉〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Gong, Haixia -- Shen, Bo -- Flevaris, Panagiotis -- Chow, Christina -- Lam, Stephen C-T -- Voyno-Yasenetskaya, Tatyana A -- Kozasa, Tohru -- Du, Xiaoping -- GM061454/GM/NIGMS NIH HHS/ -- GM074001/GM/NIGMS NIH HHS/ -- HL062350/HL/NHLBI NIH HHS/ -- HL068819/HL/NHLBI NIH HHS/ -- HL080264/HL/NHLBI NIH HHS/ -- R01 GM061454/GM/NIGMS NIH HHS/ -- R01 GM061454-09/GM/NIGMS NIH HHS/ -- R01 GM074001/GM/NIGMS NIH HHS/ -- R01 GM074001-02/GM/NIGMS NIH HHS/ -- R01 HL062350/HL/NHLBI NIH HHS/ -- R01 HL062350-09/HL/NHLBI NIH HHS/ -- R01 HL068819/HL/NHLBI NIH HHS/ -- R01 HL068819-08/HL/NHLBI NIH HHS/ -- R01 HL080264/HL/NHLBI NIH HHS/ -- R01 HL080264-04/HL/NHLBI NIH HHS/ -- New York, N.Y. -- Science. 2010 Jan 15;327(5963):340-3. doi: 10.1126/science.1174779.〈br /〉〈span class="detail_caption"〉Author address: 〈/span〉Department of Pharmacology, University of Illinois at Chicago, 835 South Wolcott Avenue, Room E403, Chicago, IL 60612, USA.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/20075254" target="_blank"〉PubMed〈/a〉
    Keywords: Animals ; Binding Sites ; Blood Platelets/*physiology ; Clot Retraction ; Fibrinogen/metabolism ; GTP-Binding Protein alpha Subunits, G12-G13/genetics/*metabolism ; Humans ; Integrin beta3/*metabolism ; Ligands ; Mice ; Mice, Inbred C57BL ; Phosphorylation ; Platelet Adhesiveness ; Platelet Glycoprotein GPIIb-IIIa Complex/*metabolism ; Protein Binding ; Protein Structure, Tertiary ; Proto-Oncogene Proteins pp60(c-src)/metabolism ; RNA, Small Interfering ; Recombinant Fusion Proteins/metabolism ; *Signal Transduction ; rhoA GTP-Binding Protein/antagonists & inhibitors/metabolism
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  • 45
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    American Association for the Advancement of Science (AAAS)
    Publication Date: 2010-09-04
    Description: 〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Marshall, Charles R -- New York, N.Y. -- Science. 2010 Sep 3;329(5996):1156-7. doi: 10.1126/science.1194924.〈br /〉〈span class="detail_caption"〉Author address: 〈/span〉Department of Integrative Biology, University of California Museum of Paleontology, University of California, Berkeley, Berkeley, CA 94720, USA. crmarshall@berkeley.edu〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/20813942" target="_blank"〉PubMed〈/a〉
    Keywords: Animals ; *Biodiversity ; Data Interpretation, Statistical ; *Databases, Factual ; *Ecosystem ; Extinction, Biological ; *Fossils ; Geography ; *Invertebrates ; Marine Biology ; Oceans and Seas ; *Paleontology ; Population Dynamics ; Time
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  • 46
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    American Association for the Advancement of Science (AAAS)
    Publication Date: 2010-06-19
    Description: 〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Kerr, Richard A -- New York, N.Y. -- Science. 2010 Jun 18;328(5985):1500-1. doi: 10.1126/science.328.5985.1500.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/20558701" target="_blank"〉PubMed〈/a〉
    Keywords: Animals ; Anthozoa/physiology ; Bicarbonates/analysis/chemistry ; Calcification, Physiologic ; Calcium Carbonate/chemistry ; Carbon Dioxide/chemistry ; *Ecosystem ; Foraminifera/physiology ; Human Activities ; Humans ; Hydrogen-Ion Concentration ; Oceans and Seas ; Seawater/*chemistry
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  • 47
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    American Association for the Advancement of Science (AAAS)
    Publication Date: 2010-07-24
    Description: 〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Vince, Gaia -- New York, N.Y. -- Science. 2010 Jul 23;329(5990):382-5. doi: 10.1126/science.329.5990.382.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/20651130" target="_blank"〉PubMed〈/a〉
    Keywords: Chile ; *Ecosystem ; *Electricity ; *Environment ; *Power Plants ; *Rivers ; Trees
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  • 48
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    American Association for the Advancement of Science (AAAS)
    Publication Date: 2010-04-03
    Description: 〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Bohannon, John -- New York, N.Y. -- Science. 2010 Apr 2;328(5974):23-5. doi: 10.1126/science.328.5974.23.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/20360072" target="_blank"〉PubMed〈/a〉
    Keywords: Animals ; *Biodiversity ; Commerce/legislation & jurisprudence ; *Conservation of Natural Resources/legislation & jurisprudence ; *Ecosystem ; Endangered Species ; Madagascar ; *Trees ; Wood
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  • 49
    Publication Date: 2010-08-28
    Description: 〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Machlis, Gary E -- McNutt, Marcia K -- New York, N.Y. -- Science. 2010 Aug 27;329(5995):1018-9. doi: 10.1126/science.1195382.〈br /〉〈span class="detail_caption"〉Author address: 〈/span〉Strategic Sciences Working Group, U.S. Department of the Interior, Washington, DC 20024, USA. gary_machlis@nps.gov〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/20798302" target="_blank"〉PubMed〈/a〉
    Keywords: *Accidents ; Animals ; Atlantic Ocean ; Decision Making ; *Disasters ; *Ecosystem ; Environmental Pollution ; Fisheries ; Forecasting ; Interdisciplinary Communication ; *Petroleum ; Planning Techniques ; Public Policy ; United States ; United States Government Agencies ; Wetlands
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  • 50
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    American Association for the Advancement of Science (AAAS)
    Publication Date: 2010-01-23
    Description: 〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Schimel, David S -- New York, N.Y. -- Science. 2010 Jan 22;327(5964):418-9. doi: 10.1126/science.1184946.〈br /〉〈span class="detail_caption"〉Author address: 〈/span〉National Ecological Observatory, Inc., 5340 Airport Boulevard, Boulder, CO 80301, USA. dschimel@naeoninc.org〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/20093461" target="_blank"〉PubMed〈/a〉
    Keywords: Carbon/*metabolism ; Climate Change ; *Climatic Processes ; Conservation of Natural Resources ; *Ecosystem ; Geography ; Israel ; Photosynthesis ; Seasons ; Temperature ; *Trees/growth & development/metabolism
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  • 51
    Publication Date: 2010-06-26
    Description: The factors determining species commonness and rarity are poorly understood, particularly in highly diverse communities. Theory predicts that interactions with neighbors of the same (conspecific) and other (heterospecific) species can influence a species' relative abundance, but empirical tests are lacking. By using a hierarchical model of survival for more than 30,000 seedlings of 180 tropical tree species on Barro Colorado Island, Panama, we tested whether species' sensitivity to neighboring individuals relates to their relative abundance in the community. We found wide variation among species in the effect of conspecific, but not heterospecific, neighbors on survival, and we found a significant relationship between the strength of conspecific neighbor effects and species abundance. Specifically, rare species suffered more from the presence of conspecific neighbors than common species did, suggesting that conspecific density dependence shapes species abundances in diverse communities.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Comita, Liza S -- Muller-Landau, Helene C -- Aguilar, Salomon -- Hubbell, Stephen P -- New York, N.Y. -- Science. 2010 Jul 16;329(5989):330-2. doi: 10.1126/science.1190772. Epub 2010 Jun 24.〈br /〉〈span class="detail_caption"〉Author address: 〈/span〉National Center for Ecological Analysis and Synthesis, 735 State Street, Suite 300, Santa Barbara, CA 93101, USA. comita@nceas.ucsb.edu〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/20576853" target="_blank"〉PubMed〈/a〉
    Keywords: Bayes Theorem ; *Biodiversity ; *Ecosystem ; Panama ; Population Density ; Seedlings/growth & development ; Species Specificity ; *Trees/growth & development ; *Tropical Climate
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  • 52
    Publication Date: 2010-07-22
    Description: Since the collapse of the pelagic fisheries off southwest Africa in the late 1960s, jellyfish biomass has increased and the structure of the Benguelan fish community has shifted, making the bearded goby (Sufflogobius bibarbatus) the new predominant prey species. Despite increased predation pressure and a harsh environment, the gobies are thriving. Here we show that physiological adaptations and antipredator and foraging behaviors underpin the success of these fish. In particular, body-tissue isotope signatures reveal that gobies consume jellyfish and sulphidic diatomaceous mud, transferring "dead-end" resources back into the food chain.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Utne-Palm, Anne C -- Salvanes, Anne G V -- Currie, Bronwen -- Kaartvedt, Stein -- Nilsson, Goran E -- Braithwaite, Victoria A -- Stecyk, Jonathan A W -- Hundt, Matthias -- van der Bank, Megan -- Flynn, Bradley -- Sandvik, Guro K -- Klevjer, Thor A -- Sweetman, Andrew K -- Bruchert, Volker -- Pittman, Karin -- Peard, Kathleen R -- Lunde, Ida G -- Strandabo, Ronnaug A U -- Gibbons, Mark J -- New York, N.Y. -- Science. 2010 Jul 16;329(5989):333-6. doi: 10.1126/science.1190708.〈br /〉〈span class="detail_caption"〉Author address: 〈/span〉Department of Biology, University of Bergen, Bergen, Norway. anne.palm@bio.uib.no〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/20647468" target="_blank"〉PubMed〈/a〉
    Keywords: *Adaptation, Physiological ; Anaerobiosis ; Animals ; Bacteria ; Behavior, Animal ; Biomass ; Cardiovascular Physiological Phenomena ; Digestion ; *Ecosystem ; Feeding Behavior ; Fisheries ; Fishes/physiology ; *Food Chain ; Geologic Sediments/microbiology ; Hydrogen Sulfide/analysis ; Namibia ; Oxygen/analysis ; Oxygen Consumption ; Perciformes/*physiology ; Population Dynamics ; Predatory Behavior ; *Scyphozoa ; Seawater/chemistry
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  • 53
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    American Association for the Advancement of Science (AAAS)
    Publication Date: 2010-01-16
    Description: 〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Gilg, Olivier -- Yoccoz, Nigel G -- New York, N.Y. -- Science. 2010 Jan 15;327(5963):276-7. doi: 10.1126/science.1184964.〈br /〉〈span class="detail_caption"〉Author address: 〈/span〉Department of Biological and Environmental Sciences, 00014 University of Helsinki, Finland. olivier.gilg@gmail.com〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/20075236" target="_blank"〉PubMed〈/a〉
    Keywords: *Animal Migration ; Animals ; Arctic Regions ; Birds/*physiology ; *Ecosystem ; *Nesting Behavior ; Population Density ; Population Dynamics ; *Predatory Behavior
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  • 54
    Publication Date: 2010-10-12
    Description: Efficient enzymatic conversion of crystalline polysaccharides is crucial for an economically and environmentally sustainable bioeconomy but remains unfavorably inefficient. We describe an enzyme that acts on the surface of crystalline chitin, where it introduces chain breaks and generates oxidized chain ends, thus promoting further degradation by chitinases. This enzymatic activity was discovered and further characterized by using mass spectrometry and chromatographic separation methods to detect oxidized products generated in the absence or presence of H(2)(18)O or (18)O(2). There are strong indications that similar enzymes exist that work on cellulose. Our findings not only demonstrate the existence of a hitherto unknown enzyme activity but also provide new avenues toward more efficient enzymatic conversion of biomass.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Vaaje-Kolstad, Gustav -- Westereng, Bjorge -- Horn, Svein J -- Liu, Zhanliang -- Zhai, Hong -- Sorlie, Morten -- Eijsink, Vincent G H -- New York, N.Y. -- Science. 2010 Oct 8;330(6001):219-22. doi: 10.1126/science.1192231.〈br /〉〈span class="detail_caption"〉Author address: 〈/span〉Department of Chemistry, Biotechnology and Food Science, Norwegian University of Life Sciences, Post Office Box 5003, 1432 As, Norway.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/20929773" target="_blank"〉PubMed〈/a〉
    Keywords: Bacterial Proteins/antagonists & inhibitors/chemistry/genetics/*metabolism ; Binding Sites ; Biocatalysis ; Biomass ; Carrier Proteins/antagonists & inhibitors/chemistry/genetics/*metabolism ; Cations, Divalent/metabolism/pharmacology ; Chitin/*metabolism ; Chitinase/*metabolism ; Chromatography, High Pressure Liquid ; Edetic Acid/pharmacology ; Enzyme Inhibitors/pharmacology ; Hydrolysis ; Isotope Labeling ; Oligosaccharides/metabolism ; Oxidation-Reduction ; Oxygen Isotopes/metabolism ; Serratia marcescens/*enzymology ; Solubility ; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization
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  • 55
    Publication Date: 2010-12-04
    Description: 〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Blight, Louise K -- Ainley, David G -- Ackley, Stephen F -- Ballard, Grant -- Ballerini, Tosca -- Brownell, Robert L Jr -- Cheng, C-H Christina -- Chiantore, Mariachiara -- Costa, Daniel -- Coulter, Malcolm C -- Dayton, Paul -- Devries, Arthur L -- Dunbar, Robert -- Earle, Sylvia -- Eastman, Joseph T -- Emslie, Steven D -- Evans, Clive W -- Garrott, Robert A -- Kim, Stacy -- Kooyman, Gerald -- Lescroel, Amelie -- Lizotte, Michael -- Massaro, Melanie -- Olmastroni, Silvia -- Ponganis, Paul J -- Russell, Joellen -- Siniff, Donald B -- Smith, Walker O Jr -- Stewart, Brent S -- Stirling, Ian -- Willis, Jay -- Wilson, Peter -- Woehler, Eric J -- New York, N.Y. -- Science. 2010 Dec 3;330(6009):1316. doi: 10.1126/science.330.6009.1316.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/21127229" target="_blank"〉PubMed〈/a〉
    Keywords: Animals ; Antarctic Regions ; *Bass ; Certification ; *Conservation of Natural Resources ; *Ecosystem ; Fisheries/*standards
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    American Association for the Advancement of Science (AAAS)
    Publication Date: 2010-11-13
    Description: 〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Malakoff, David -- New York, N.Y. -- Science. 2010 Nov 12;330(6006):910-1. doi: 10.1126/science.330.6006.910.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/21071645" target="_blank"〉PubMed〈/a〉
    Keywords: Acid Rain/*legislation & jurisprudence ; Air Pollution/*legislation & jurisprudence ; Animals ; Biodiversity ; *Ecosystem ; Fishes ; *Fresh Water/chemistry/microbiology ; Hydrogen-Ion Concentration ; Sulfur ; United States
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  • 57
    Publication Date: 2010-05-22
    Description: 〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Kerr, Richard A -- Kintisch, Eli -- Schenkman, Lauren -- Stokstad, Erik -- New York, N.Y. -- Science. 2010 May 21;328(5981):962-3. doi: 10.1126/science.328.5981.962.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/20489000" target="_blank"〉PubMed〈/a〉
    Keywords: *Accidents ; Animals ; Atlantic Ocean ; *Disasters ; *Ecosystem ; Environmental Monitoring ; *Environmental Pollution ; Fisheries ; Food Chain ; *Petroleum ; Plants ; Wetlands
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  • 58
    Publication Date: 2010-10-16
    Description: 〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Kerr, Richard A -- Stokstad, Erik -- New York, N.Y. -- Science. 2010 Oct 15;330(6002):302-3. doi: 10.1126/science.330.6002.302.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/20947731" target="_blank"〉PubMed〈/a〉
    Keywords: *Advisory Committees ; *Ecosystem ; *Environmental Pollution ; *Information Dissemination ; *Petroleum ; United States ; United States Government Agencies
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  • 59
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    American Association for the Advancement of Science (AAAS)
    Publication Date: 2010-06-05
    Description: 〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Peh, Kelvin S-H -- New York, N.Y. -- Science. 2010 Jun 4;328(5983):1228-9. doi: 10.1126/science.328.5983.1228-d.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/20522756" target="_blank"〉PubMed〈/a〉
    Keywords: Biodiversity ; China ; *Conservation of Natural Resources ; *Ecosystem ; Environment ; India ; *International Cooperation ; Military Personnel
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  • 60
    Publication Date: 2010-01-09
    Description: Large-scale biodiversity gradients among environments and habitats are usually attributed to a complex array of ecological and evolutionary factors. We tested the evolutionary component of such gradients by compiling the environments of the geologically oldest occurrences of marine genera and using sampling standardization to assess if originations tended to be clustered in particular environments. Shallow, tropical environments and carbonate substrates all tend to have harbored high origination rates. Diversity within these environments tended to be preferentially generated in reefs, probably because of their habitat complexity. Reefs were also prolific at exporting diversity to other environments, which might be a consequence of low-diversity habitats being more susceptible to invasions.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Kiessling, Wolfgang -- Simpson, Carl -- Foote, Michael -- New York, N.Y. -- Science. 2010 Jan 8;327(5962):196-8. doi: 10.1126/science.1182241.〈br /〉〈span class="detail_caption"〉Author address: 〈/span〉Museum fur Naturkunde, Leibniz Institute for Research on Evolution and Biodiversity at the Humboldt University Berlin, 10115 Berlin, Germany. wolfgang.kiessling@mfn-berlin.de〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/20056888" target="_blank"〉PubMed〈/a〉
    Keywords: Animals ; *Anthozoa ; *Biodiversity ; *Biological Evolution ; Calcium Carbonate ; *Ecosystem ; Environment ; Fishes ; *Fossils ; Geography ; *Invertebrates/classification
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  • 61
    Publication Date: 2010-10-12
    Description: Oceanic bacteria perform many environmental functions, including biogeochemical cycling of many elements, metabolizing of greenhouse gases, functioning in oceanic food webs (microbial loop), and producing valuable natural products and viruses. We demonstrate that the widespread capability of marine bacteria to participate in horizontal gene transfer (HGT) in coastal and oceanic environments may be the result of gene transfer agents (GTAs), viral-like particles produced by alpha-Proteobacteria. We documented GTA-mediated gene transfer frequencies a thousand to a hundred million times higher than prior estimates of HGT in the oceans, with as high as 47% of the culturable natural microbial community confirmed as gene recipients. These findings suggest a plausible mechanism by which marine bacteria acquire novel traits, thus ensuring resilience in the face of environmental change.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉McDaniel, Lauren D -- Young, Elizabeth -- Delaney, Jennifer -- Ruhnau, Fabian -- Ritchie, Kim B -- Paul, John H -- New York, N.Y. -- Science. 2010 Oct 1;330(6000):50. doi: 10.1126/science.1192243.〈br /〉〈span class="detail_caption"〉Author address: 〈/span〉University of South Florida College of Marine Science, St. Petersburg, FL 33701, USA. mcdaniel@marine.usf.edu〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/20929803" target="_blank"〉PubMed〈/a〉
    Keywords: Adaptation, Physiological ; DNA Transposable Elements ; Drug Resistance, Bacterial/genetics ; *Ecosystem ; Flavobacterium/drug effects/genetics ; Flexibacter/drug effects/genetics ; *Gene Transfer, Horizontal ; Kanamycin Resistance/genetics ; Oceans and Seas ; Prophages/genetics ; Rhodobacteraceae/drug effects/*genetics/virology ; Seawater/*microbiology ; Streptomycin/metabolism/pharmacology
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    American Association for the Advancement of Science (AAAS)
    Publication Date: 2010-06-19
    Description: Climate change, rising atmospheric carbon dioxide, excess nutrient inputs, and pollution in its many forms are fundamentally altering the chemistry of the ocean, often on a global scale and, in some cases, at rates greatly exceeding those in the historical and recent geological record. Major observed trends include a shift in the acid-base chemistry of seawater, reduced subsurface oxygen both in near-shore coastal water and in the open ocean, rising coastal nitrogen levels, and widespread increase in mercury and persistent organic pollutants. Most of these perturbations, tied either directly or indirectly to human fossil fuel combustion, fertilizer use, and industrial activity, are projected to grow in coming decades, resulting in increasing negative impacts on ocean biota and marine resources.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Doney, Scott C -- New York, N.Y. -- Science. 2010 Jun 18;328(5985):1512-6. doi: 10.1126/science.1185198.〈br /〉〈span class="detail_caption"〉Author address: 〈/span〉Marine Chemistry and Geochemistry Department, Woods Hole Oceanographic Institution, Woods Hole, MA 02543, USA. sdoney@whoi.edu〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/20558706" target="_blank"〉PubMed〈/a〉
    Keywords: Animals ; Atmosphere ; Carbon Dioxide/analysis ; Climate Change ; *Ecosystem ; Fossil Fuels ; *Human Activities ; Humans ; Hydrogen-Ion Concentration ; Industrial Waste/analysis ; Mercury/analysis ; Nitrogen/analysis ; Oceans and Seas ; Oxygen/analysis ; Photosynthesis ; *Seawater/chemistry/microbiology ; Water Pollutants/analysis
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    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
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  • 63
    Publication Date: 2010-10-12
    Description: 〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Poiner, Ian -- New York, N.Y. -- Science. 2010 Oct 1;330(6000):25. doi: 10.1126/science.330.6000.25.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/20929784" target="_blank"〉PubMed〈/a〉
    Keywords: Animals ; *Biodiversity ; Biomass ; *Ecosystem ; Marine Biology ; Oceans and Seas
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  • 64
    Publication Date: 2010-02-13
    Description: Microorganisms can switch from a planktonic, free-swimming life-style to a sessile, colonial state, called a biofilm, which confers resistance to environmental stress. Conversion between the motile and biofilm life-styles has been attributed to increased levels of the prokaryotic second messenger cyclic di-guanosine monophosphate (c-di-GMP), yet the signaling mechanisms mediating such a global switch are poorly understood. Here we show that the transcriptional regulator VpsT from Vibrio cholerae directly senses c-di-GMP to inversely control extracellular matrix production and motility, which identifies VpsT as a master regulator for biofilm formation. Rather than being regulated by phosphorylation, VpsT undergoes a change in oligomerization on c-di-GMP binding.〈br /〉〈br /〉〈a href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2828054/" target="_blank"〉〈img src="https://static.pubmed.gov/portal/portal3rc.fcgi/4089621/img/3977009" border="0"〉〈/a〉   〈a href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2828054/" target="_blank"〉This paper as free author manuscript - peer-reviewed and accepted for publication〈/a〉〈br /〉〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Krasteva, Petya V -- Fong, Jiunn C N -- Shikuma, Nicholas J -- Beyhan, Sinem -- Navarro, Marcos V A S -- Yildiz, Fitnat H -- Sondermann, Holger -- 1R01GM081373/GM/NIGMS NIH HHS/ -- P30 EB009998/EB/NIBIB NIH HHS/ -- R01 AI055987/AI/NIAID NIH HHS/ -- R01 AI055987-06A1/AI/NIAID NIH HHS/ -- R01 GM081373/GM/NIGMS NIH HHS/ -- R01 GM081373-03/GM/NIGMS NIH HHS/ -- R01AI055987/AI/NIAID NIH HHS/ -- New York, N.Y. -- Science. 2010 Feb 12;327(5967):866-8. doi: 10.1126/science.1181185.〈br /〉〈span class="detail_caption"〉Author address: 〈/span〉Department of Molecular Medicine, College of Veterinary Medicine, Cornell University, Ithaca, NY 14853, USA.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/20150502" target="_blank"〉PubMed〈/a〉
    Keywords: Amino Acid Motifs ; Bacterial Proteins/chemistry/genetics/*metabolism ; Binding Sites ; Biofilms/*growth & development ; Crystallography, X-Ray ; Cyclic GMP/*analogs & derivatives/metabolism ; DNA, Bacterial/metabolism ; Dimerization ; Extracellular Matrix/*metabolism ; Gene Expression Profiling ; Gene Expression Regulation, Bacterial ; Models, Molecular ; Movement ; Point Mutation ; Polysaccharides, Bacterial/genetics/metabolism ; Protein Folding ; Protein Multimerization ; Protein Structure, Tertiary ; Signal Transduction ; Transcription Factors/chemistry/genetics/*metabolism ; Transcription, Genetic ; Vibrio cholerae O1/cytology/genetics/*physiology
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  • 65
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    American Association for the Advancement of Science (AAAS)
    Publication Date: 2010-04-24
    Description: 〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Pennisi, Elizabeth -- New York, N.Y. -- Science. 2010 Apr 23;328(5977):418-20. doi: 10.1126/science.328.5977.418.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/20413469" target="_blank"〉PubMed〈/a〉
    Keywords: Access to Information ; Animals ; Biodiversity ; Climatic Processes ; Data Collection ; *Ecology/economics/instrumentation/methods/organization & administration ; *Ecosystem ; *Environment ; *Environmental Monitoring/instrumentation/methods ; Financing, Government ; National Academy of Sciences (U.S.) ; United States ; United States Government Agencies/economics
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  • 66
    Publication Date: 2010-04-24
    Description: The structure of the sodium-benzylhydantoin transport protein Mhp1 from Microbacterium liquefaciens comprises a five-helix inverted repeat, which is widespread among secondary transporters. Here, we report the crystal structure of an inward-facing conformation of Mhp1 at 3.8 angstroms resolution, complementing its previously described structures in outward-facing and occluded states. From analyses of the three structures and molecular dynamics simulations, we propose a mechanism for the transport cycle in Mhp1. Switching from the outward- to the inward-facing state, to effect the inward release of sodium and benzylhydantoin, is primarily achieved by a rigid body movement of transmembrane helices 3, 4, 8, and 9 relative to the rest of the protein. This forms the basis of an alternating access mechanism applicable to many transporters of this emerging superfamily.〈br /〉〈br /〉〈a href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2885435/" target="_blank"〉〈img src="https://static.pubmed.gov/portal/portal3rc.fcgi/4089621/img/3977009" border="0"〉〈/a〉   〈a href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2885435/" target="_blank"〉This paper as free author manuscript - peer-reviewed and accepted for publication〈/a〉〈br /〉〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Shimamura, Tatsuro -- Weyand, Simone -- Beckstein, Oliver -- Rutherford, Nicholas G -- Hadden, Jonathan M -- Sharples, David -- Sansom, Mark S P -- Iwata, So -- Henderson, Peter J F -- Cameron, Alexander D -- 062164/Z/00/Z/Wellcome Trust/United Kingdom -- 079209/Wellcome Trust/United Kingdom -- BB/C51725/Biotechnology and Biological Sciences Research Council/United Kingdom -- BB/G020043/1/Biotechnology and Biological Sciences Research Council/United Kingdom -- BB/G023425/1/Biotechnology and Biological Sciences Research Council/United Kingdom -- BBS/B/14418/Biotechnology and Biological Sciences Research Council/United Kingdom -- New York, N.Y. -- Science. 2010 Apr 23;328(5977):470-3. doi: 10.1126/science.1186303.〈br /〉〈span class="detail_caption"〉Author address: 〈/span〉Division of Molecular Biosciences, Membrane Protein Crystallography Group, Imperial College, London SW7 2AZ, UK.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/20413494" target="_blank"〉PubMed〈/a〉
    Keywords: Actinomycetales/*chemistry/metabolism ; Amino Acid Motifs ; Bacterial Proteins/chemistry/metabolism ; Binding Sites ; Biological Transport ; Crystallography, X-Ray ; Hydantoins/chemistry/*metabolism ; Ion Transport ; Membrane Transport Proteins/*chemistry/*metabolism ; Models, Molecular ; Molecular Dynamics Simulation ; Protein Conformation ; Protein Folding ; Protein Structure, Secondary ; Sodium/*metabolism
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  • 67
    Publication Date: 2010-11-13
    Description: Nitrogen cycling is normally thought to dominate the biogeochemistry and microbial ecology of oxygen-minimum zones in marine environments. Through a combination of molecular techniques and process rate measurements, we showed that both sulfate reduction and sulfide oxidation contribute to energy flux and elemental cycling in oxygen-free waters off the coast of northern Chile. These processes may have been overlooked because in nature, the sulfide produced by sulfate reduction immediately oxidizes back to sulfate. This cryptic sulfur cycle is linked to anammox and other nitrogen cycling processes, suggesting that it may influence biogeochemical cycling in the global ocean.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Canfield, Don E -- Stewart, Frank J -- Thamdrup, Bo -- De Brabandere, Loreto -- Dalsgaard, Tage -- Delong, Edward F -- Revsbech, Niels Peter -- Ulloa, Osvaldo -- New York, N.Y. -- Science. 2010 Dec 3;330(6009):1375-8. doi: 10.1126/science.1196889. Epub 2010 Nov 11.〈br /〉〈span class="detail_caption"〉Author address: 〈/span〉Institute of Biology and Nordic Center for Earth Evolution, University of Southern Denmark, Campusvej 55, 5230 Odense M, Denmark. dec@biology.sdu.dk〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/21071631" target="_blank"〉PubMed〈/a〉
    Keywords: Anaerobiosis ; Bacteria/classification/genetics/*metabolism ; Chile ; Deltaproteobacteria/classification/genetics/metabolism ; Denitrification ; *Ecosystem ; Gammaproteobacteria/classification/genetics/metabolism ; Genes, Bacterial ; Metagenome ; Nitrates/metabolism ; Nitrites/metabolism ; Nitrogen Cycle ; Oxidation-Reduction ; Oxygen/*analysis ; Pacific Ocean ; Quaternary Ammonium Compounds/metabolism ; Seawater/chemistry/*microbiology ; Sequence Analysis, DNA ; Sulfates/metabolism ; Sulfides/metabolism ; Sulfur/*metabolism
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  • 68
    Publication Date: 2010-07-22
    Description: Sea surface temperature (SST) across much of the tropics has increased by 0.4 degrees to 1 degrees C since the mid-1970s. A parallel increase in the frequency and extent of coral bleaching and mortality has fueled concern that climate change poses a major threat to the survival of coral reef ecosystems worldwide. Here we show that steadily rising SSTs, not ocean acidification, are already driving dramatic changes in the growth of an important reef-building coral in the central Red Sea. Three-dimensional computed tomography analyses of the massive coral Diploastrea heliopora reveal that skeletal growth of apparently healthy colonies has declined by 30% since 1998. The same corals responded to a short-lived warm event in 1941/1942, but recovered within 3 years as the ocean cooled. Combining our data with climate model simulations by the Intergovernmental Panel on Climate Change, we predict that should the current warming trend continue, this coral could cease growing altogether by 2070.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Cantin, Neal E -- Cohen, Anne L -- Karnauskas, Kristopher B -- Tarrant, Ann M -- McCorkle, Daniel C -- New York, N.Y. -- Science. 2010 Jul 16;329(5989):322-5. doi: 10.1126/science.1190182.〈br /〉〈span class="detail_caption"〉Author address: 〈/span〉Woods Hole Oceanographic Institution, Woods Hole, MA 02543, USA.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/20647466" target="_blank"〉PubMed〈/a〉
    Keywords: Animals ; Anthozoa/*growth & development ; *Climate Change ; *Ecosystem ; Eukaryota/growth & development ; Hydrogen-Ion Concentration ; Indian Ocean ; Seasons ; *Seawater ; Stress, Physiological ; Symbiosis ; *Temperature
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  • 69
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    American Association for the Advancement of Science (AAAS)
    Publication Date: 2010-01-30
    Description: 〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Pennisi, Elizabeth -- New York, N.Y. -- Science. 2010 Jan 29;327(5965):519. doi: 10.1126/science.327.5965.519.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/20110481" target="_blank"〉PubMed〈/a〉
    Keywords: Animals ; *Anthozoa/classification/genetics ; Biodiversity ; *Biological Evolution ; Cnidaria/classification/genetics ; *Ecosystem ; Genes ; Genetic Speciation ; Geologic Sediments ; Phylogeny ; *Seawater
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  • 70
    Publication Date: 2010-10-28
    Description: Quantitative scenarios are coming of age as a tool for evaluating the impact of future socioeconomic development pathways on biodiversity and ecosystem services. We analyze global terrestrial, freshwater, and marine biodiversity scenarios using a range of measures including extinctions, changes in species abundance, habitat loss, and distribution shifts, as well as comparing model projections to observations. Scenarios consistently indicate that biodiversity will continue to decline over the 21st century. However, the range of projected changes is much broader than most studies suggest, partly because there are major opportunities to intervene through better policies, but also because of large uncertainties in projections.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Pereira, Henrique M -- Leadley, Paul W -- Proenca, Vania -- Alkemade, Rob -- Scharlemann, Jorn P W -- Fernandez-Manjarres, Juan F -- Araujo, Miguel B -- Balvanera, Patricia -- Biggs, Reinette -- Cheung, William W L -- Chini, Louise -- Cooper, H David -- Gilman, Eric L -- Guenette, Sylvie -- Hurtt, George C -- Huntington, Henry P -- Mace, Georgina M -- Oberdorff, Thierry -- Revenga, Carmen -- Rodrigues, Patricia -- Scholes, Robert J -- Sumaila, Ussif Rashid -- Walpole, Matt -- New York, N.Y. -- Science. 2010 Dec 10;330(6010):1496-501. doi: 10.1126/science.1196624. Epub 2010 Oct 26.〈br /〉〈span class="detail_caption"〉Author address: 〈/span〉Centro de Biologia Ambiental, Faculdade de Ciencias da Universidade de Lisboa, 1749-016 Lisboa, Portugal. hpereira@fc.ul.pt〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/20978282" target="_blank"〉PubMed〈/a〉
    Keywords: Animals ; Aquatic Organisms ; *Biodiversity ; Conservation of Natural Resources ; *Ecosystem ; Extinction, Biological ; Forecasting ; Models, Biological ; Plants ; Policy ; Population Dynamics
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  • 71
    Publication Date: 2010-10-16
    Description: 〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Perrings, C -- Naeem, S -- Ahrestani, F -- Bunker, D E -- Burkill, P -- Canziani, G -- Elmqvist, T -- Ferrati, R -- Fuhrman, J -- Jaksic, F -- Kawabata, Z -- Kinzig, A -- Mace, G M -- Milano, F -- Mooney, H -- Prieur-Richard, A-H -- Tschirhart, J -- Weisser, W -- New York, N.Y. -- Science. 2010 Oct 15;330(6002):323-4. doi: 10.1126/science.1196431.〈br /〉〈span class="detail_caption"〉Author address: 〈/span〉Arizona State University, Tempe, AZ 85287, USA. Charles.Perrings@asu.edu〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/20947748" target="_blank"〉PubMed〈/a〉
    Keywords: *Biodiversity ; *Conservation of Natural Resources/trends ; *Ecosystem ; Environment ; Forecasting ; International Cooperation
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  • 72
    Publication Date: 2010-02-13
    Description: 〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Wilson, Edward O -- New York, N.Y. -- Science. 2010 Feb 12;327(5967):775. doi: 10.1126/science.327.5967.775.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/20150461" target="_blank"〉PubMed〈/a〉
    Keywords: Animals ; *Ants ; Biology ; *Ecosystem ; *Literature, Modern
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  • 73
    Publication Date: 2010-06-19
    Description: T cells transformed by Herpesvirus saimiri express seven viral U-rich noncoding RNAs of unknown function called HSURs. We noted that conserved sequences in HSURs 1 and 2 constitute potential binding sites for three host-cell microRNAs (miRNAs). Coimmunoprecipitation experiments confirmed that HSURs 1 and 2 interact with the predicted miRNAs in virally transformed T cells. The abundance of one of these miRNAs, miR-27, is dramatically lowered in transformed cells, with consequent effects on the expression of miR-27 target genes. Transient knockdown and ectopic expression of HSUR 1 demonstrate that it directs degradation of mature miR-27 in a sequence-specific and binding-dependent manner. This viral strategy illustrates use of a ncRNA to manipulate host-cell gene expression via the miRNA pathway.〈br /〉〈br /〉〈a href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3075239/" target="_blank"〉〈img src="https://static.pubmed.gov/portal/portal3rc.fcgi/4089621/img/3977009" border="0"〉〈/a〉   〈a href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3075239/" target="_blank"〉This paper as free author manuscript - peer-reviewed and accepted for publication〈/a〉〈br /〉〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Cazalla, Demian -- Yario, Therese -- Steitz, Joan A -- CA16038/CA/NCI NIH HHS/ -- P01 CA016038/CA/NCI NIH HHS/ -- Howard Hughes Medical Institute/ -- New York, N.Y. -- Science. 2010 Jun 18;328(5985):1563-6. doi: 10.1126/science.1187197.〈br /〉〈span class="detail_caption"〉Author address: 〈/span〉Department of Molecular Biophysics and Biochemistry, Howard Hughes Medical Institute, Yale University School of Medicine, Boyer Center for Molecular Medicine, 295 Congress Avenue, New Haven, CT 06536, USA.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/20558719" target="_blank"〉PubMed〈/a〉
    Keywords: Animals ; Base Pairing ; Binding Sites ; Callithrix ; Cell Line, Transformed ; Cell Transformation, Viral ; Conserved Sequence ; *Down-Regulation ; Herpesvirus 2, Saimiriine/*genetics/metabolism ; Humans ; Jurkat Cells ; MicroRNAs/chemistry/genetics/*metabolism ; *RNA Stability ; RNA, Untranslated/chemistry/*metabolism ; RNA, Viral/chemistry/*metabolism ; T-Lymphocytes
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  • 74
    Publication Date: 2010-03-13
    Description: 〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Wasser, Samuel -- Poole, Joyce -- Lee, Phyllis -- Lindsay, Keith -- Dobson, Andrew -- Hart, John -- Douglas-Hamilton, Iain -- Wittemyer, George -- Granli, Petter -- Morgan, Bethan -- Gunn, Jody -- Alberts, Susan -- Beyers, Rene -- Chiyo, Patrick -- Croze, Harvey -- Estes, Richard -- Gobush, Kathleen -- Joram, Ponjoli -- Kikoti, Alfred -- Kingdon, Jonathan -- King, Lucy -- Macdonald, David -- Moss, Cynthia -- Mutayoba, Benezeth -- Njumbi, Steve -- Omondi, Patrick -- Nowak, Katarzyna -- New York, N.Y. -- Science. 2010 Mar 12;327(5971):1331-2. doi: 10.1126/science.1187811.〈br /〉〈span class="detail_caption"〉Author address: 〈/span〉University of Washington, Seattle, WA 98195, USA. wassers@u.washington.edu〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/20223971" target="_blank"〉PubMed〈/a〉
    Keywords: Animals ; *Commerce/legislation & jurisprudence ; *Conservation of Natural Resources ; Crime ; *Ecosystem ; *Elephants ; *Endangered Species ; International Cooperation ; Population Dynamics ; Tanzania ; Trees ; Zambia
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  • 75
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    American Association for the Advancement of Science (AAAS)
    Publication Date: 2010-07-31
    Description: Barton et al. (Reports, 19 March 2010, p. 1509) argued that stable conditions enable neutral coexistence of many phytoplankton species in the tropical oceans, whereas seasonal variation causes low biodiversity in subpolar oceans. However, their model prediction is not robust. A minor deviation from the neutrality assumption favors coexistence in fluctuating rather than stable environments.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Huisman, Jef -- New York, N.Y. -- Science. 2010 Jul 30;329(5991):512; author reply 512. doi: 10.1126/science.1189880.〈br /〉〈span class="detail_caption"〉Author address: 〈/span〉Aquatic Microbiology, Institute for Biodiversity and Ecosystem Dynamics, University of Amsterdam, Post Office Box 94248, 1090 GE Amsterdam, Netherlands. j.huisman@uva.nl〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/20671171" target="_blank"〉PubMed〈/a〉
    Keywords: *Biodiversity ; *Ecosystem ; Environment ; Geography ; Models, Biological ; Oceans and Seas ; *Phytoplankton/growth & development/physiology ; Population Dynamics ; Seasons ; *Seawater
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  • 76
    Publication Date: 2010-07-03
    Description: Proton-pumping respiratory complex I is one of the largest and most complicated membrane protein complexes. Its function is critical for efficient energy supply in aerobic cells, and malfunctions are implicated in many neurodegenerative disorders. Here, we report an x-ray crystallographic analysis of mitochondrial complex I. The positions of all iron-sulfur clusters relative to the membrane arm were determined in the complete enzyme complex. The ubiquinone reduction site resides close to 30 angstroms above the membrane domain. The arrangement of functional modules suggests conformational coupling of redox chemistry with proton pumping and essentially excludes direct mechanisms. We suggest that a approximately 60-angstrom-long helical transmission element is critical for transducing conformational energy to proton-pumping elements in the distal module of the membrane arm.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Hunte, Carola -- Zickermann, Volker -- Brandt, Ulrich -- New York, N.Y. -- Science. 2010 Jul 23;329(5990):448-51. doi: 10.1126/science.1191046. Epub 2010 Jul 1.〈br /〉〈span class="detail_caption"〉Author address: 〈/span〉Institute for Biochemistry and Molecular Biology, Centre for Biological Signalling Studies (BIOSS), University of Freiburg, D-79104 Freiburg, Germany.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/20595580" target="_blank"〉PubMed〈/a〉
    Keywords: Amino Acid Sequence ; Binding Sites ; Crystallography, X-Ray ; Electron Transport Complex I/*chemistry/*metabolism ; Fungal Proteins/chemistry/metabolism ; Iron/chemistry ; Mitochondria/enzymology ; Mitochondrial Proteins/*chemistry/*metabolism ; Models, Molecular ; Molecular Sequence Data ; Oxidation-Reduction ; Protein Conformation ; Protein Structure, Quaternary ; Protein Structure, Tertiary ; Protein Subunits/chemistry/metabolism ; Protons ; Sulfur/chemistry ; Ubiquinone/chemistry/metabolism ; Yarrowia/*enzymology
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  • 77
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    American Association for the Advancement of Science (AAAS)
    Publication Date: 2010-03-27
    Description: 〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Stokstad, Erik -- New York, N.Y. -- Science. 2010 Mar 26;327(5973):1574-5. doi: 10.1126/science.327.5973.1574.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/20339047" target="_blank"〉PubMed〈/a〉
    Keywords: Animals ; California ; *Conservation of Natural Resources/economics/legislation & jurisprudence ; *Ecosystem ; Fisheries ; *Fishes ; Guidelines as Topic ; Models, Biological ; Models, Economic ; Pacific Ocean ; Politics
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  • 78
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    American Association for the Advancement of Science (AAAS)
    Publication Date: 2010-07-03
    Description: 〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Puyravaud, Jean-Philippe -- Davidar, Priya -- Laurance, William F -- New York, N.Y. -- Science. 2010 Jul 2;329(5987):32. doi: 10.1126/science.329.5987.32-b.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/20595597" target="_blank"〉PubMed〈/a〉
    Keywords: *Conservation of Natural Resources ; *Ecosystem ; India ; *Trees
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  • 79
    Publication Date: 2010-10-12
    Description: Marx and Uhen (Reports, 19 February 2010, p. 993) suggested that correlated diversity changes in the fossil record of whales and diatoms reflects secular evolutionary signals of underlying ecological drivers. We question the meaning of this association and outline avenues for more complete testing of correlations between productivity and marine consumers through geologic time.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Pyenson, Nicholas D -- Irmis, Randall B -- Lipps, Jere H -- New York, N.Y. -- Science. 2010 Oct 8;330(6001):178; author reply 178. doi: 10.1126/science.1189866.〈br /〉〈span class="detail_caption"〉Author address: 〈/span〉Department of Zoology, 6270 University Boulevard, University of British Columbia, Vancouver, BC V6T 1Z4, Canada. pyensonn@si.edu〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/20929760" target="_blank"〉PubMed〈/a〉
    Keywords: Animals ; Biodiversity ; *Biological Evolution ; Climate ; *Diatoms ; *Ecosystem ; Food Chain ; *Fossils ; Geologic Sediments ; Oceans and Seas ; *Whales
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    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
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  • 80
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    American Association for the Advancement of Science (AAAS)
    Publication Date: 2010-03-20
    Description: 〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Wright, Bruce -- New York, N.Y. -- Science. 2010 Mar 19;327(5972):1452. doi: 10.1126/science.327.5972.1452-a.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/20299575" target="_blank"〉PubMed〈/a〉
    Keywords: Alaska ; Animals ; *Ecosystem ; *Fisheries ; Mining ; *Salmon
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  • 81
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    American Association for the Advancement of Science (AAAS)
    Publication Date: 2010-06-05
    Description: 〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Charles, Daniel -- New York, N.Y. -- Science. 2010 Jun 4;328(5983):1225. doi: 10.1126/science.328.5983.1225.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/20522753" target="_blank"〉PubMed〈/a〉
    Keywords: *Agriculture/economics ; Animal Husbandry ; Animals ; *Ecosystem ; *Poaceae ; Ukraine
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  • 82
    Publication Date: 2010-07-24
    Description: DNA methylation at proximal promoters facilitates lineage restriction by silencing cell type-specific genes. However, euchromatic DNA methylation frequently occurs in regions outside promoters. The functions of such nonproximal promoter DNA methylation are unclear. Here we show that the de novo DNA methyltransferase Dnmt3a is expressed in postnatal neural stem cells (NSCs) and is required for neurogenesis. Genome-wide analysis of postnatal NSCs indicates that Dnmt3a occupies and methylates intergenic regions and gene bodies flanking proximal promoters of a large cohort of transcriptionally permissive genes, many of which encode regulators of neurogenesis. Surprisingly, Dnmt3a-dependent nonproximal promoter methylation promotes expression of these neurogenic genes by functionally antagonizing Polycomb repression. Thus, nonpromoter DNA methylation by Dnmt3a may be used for maintaining active chromatin states of genes critical for development.〈br /〉〈br /〉〈a href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3539760/" target="_blank"〉〈img src="https://static.pubmed.gov/portal/portal3rc.fcgi/4089621/img/3977009" border="0"〉〈/a〉   〈a href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3539760/" target="_blank"〉This paper as free author manuscript - peer-reviewed and accepted for publication〈/a〉〈br /〉〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Wu, Hao -- Coskun, Volkan -- Tao, Jifang -- Xie, Wei -- Ge, Weihong -- Yoshikawa, Kazuaki -- Li, En -- Zhang, Yi -- Sun, Yi Eve -- Howard Hughes Medical Institute/ -- New York, N.Y. -- Science. 2010 Jul 23;329(5990):444-8. doi: 10.1126/science.1190485.〈br /〉〈span class="detail_caption"〉Author address: 〈/span〉Department of Molecular and Medical Pharmacology, University of California Los Angeles (UCLA), Los Angeles, CA 90095, USA. haowu7@gmail.com〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/20651149" target="_blank"〉PubMed〈/a〉
    Keywords: Animals ; Binding Sites ; Brain/cytology/growth & development/*metabolism ; Chromatin Immunoprecipitation ; DNA (Cytosine-5-)-Methyltransferase/*metabolism ; *DNA Methylation ; DNA, Intergenic ; Gene Expression Profiling ; *Gene Expression Regulation, Developmental ; Genome ; Histones/genetics/metabolism ; Mice ; Mice, Knockout ; Nervous System/growth & development ; Neurogenesis/*genetics ; Neuroglia/cytology ; Neurons/*cytology/metabolism ; Polycomb-Group Proteins ; Promoter Regions, Genetic ; Repressor Proteins/metabolism ; Stem Cells/*metabolism ; *Transcription, Genetic
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  • 83
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    American Association for the Advancement of Science (AAAS)
    Publication Date: 2010-01-30
    Description: 〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Miller, Greg -- New York, N.Y. -- Science. 2010 Jan 29;327(5965):512-3. doi: 10.1126/science.327.5965.512.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/20110475" target="_blank"〉PubMed〈/a〉
    Keywords: Animals ; California ; Conservation of Natural Resources ; *Ecosystem ; *Endangered Species ; *Fisheries ; *Oncorhynchus kisutch/physiology ; Population Dynamics ; Reproduction
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  • 84
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    American Association for the Advancement of Science (AAAS)
    Publication Date: 2010-10-12
    Description: 〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Stokstad, Erik -- New York, N.Y. -- Science. 2010 Sep 24;329(5999):1596-7. doi: 10.1126/science.329.5999.1596.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/20929825" target="_blank"〉PubMed〈/a〉
    Keywords: Animals ; Antarctic Regions ; *Bass ; Certification ; *Conservation of Natural Resources ; *Ecosystem ; Fisheries/*standards ; *Organizations, Nonprofit
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  • 85
    Publication Date: 2010-03-27
    Description: Phosphoinositide 3-kinases (PI3Ks) are lipid kinases with diverse roles in health and disease. The primordial PI3K, Vps34, is present in all eukaryotes and has essential roles in autophagy, membrane trafficking, and cell signaling. We solved the crystal structure of Vps34 at 2.9 angstrom resolution, which revealed a constricted adenine-binding pocket, suggesting the reason that specific inhibitors of this class of PI3K have proven elusive. Both the phosphoinositide-binding loop and the carboxyl-terminal helix of Vps34 mediate catalysis on membranes and suppress futile adenosine triphosphatase cycles. Vps34 appears to alternate between a closed cytosolic form and an open form on the membrane. Structures of Vps34 complexes with a series of inhibitors reveal the reason that an autophagy inhibitor preferentially inhibits Vps34 and underpin the development of new potent and specific Vps34 inhibitors.〈br /〉〈br /〉〈a href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2860105/" target="_blank"〉〈img src="https://static.pubmed.gov/portal/portal3rc.fcgi/4089621/img/3977009" border="0"〉〈/a〉   〈a href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2860105/" target="_blank"〉This paper as free author manuscript - peer-reviewed and accepted for publication〈/a〉〈br /〉〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Miller, Simon -- Tavshanjian, Brandon -- Oleksy, Arkadiusz -- Perisic, Olga -- Houseman, Benjamin T -- Shokat, Kevan M -- Williams, Roger L -- MC_U105184308/Medical Research Council/United Kingdom -- U.1051.03.014(78824)/Medical Research Council/United Kingdom -- Howard Hughes Medical Institute/ -- New York, N.Y. -- Science. 2010 Mar 26;327(5973):1638-42. doi: 10.1126/science.1184429.〈br /〉〈span class="detail_caption"〉Author address: 〈/span〉Medical Research Council Laboratory of Molecular Biology, Hills Road, Cambridge CB2 0QH, UK.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/20339072" target="_blank"〉PubMed〈/a〉
    Keywords: Adenine/*analogs & derivatives/metabolism/pharmacology ; Adenosine Triphosphatases/metabolism ; Animals ; Autophagy/*drug effects ; Binding Sites ; Catalysis ; Catalytic Domain ; Cell Membrane/metabolism ; Crystallography, X-Ray ; Drosophila Proteins/*antagonists & inhibitors/*chemistry/genetics/metabolism ; Drosophila melanogaster ; Enzyme Inhibitors/chemical synthesis/chemistry/*metabolism/pharmacology ; Furans/chemistry/metabolism/pharmacology ; Humans ; Hydrophobic and Hydrophilic Interactions ; Models, Molecular ; Phosphatidylinositol 3-Kinases/*antagonists & ; inhibitors/*chemistry/genetics/metabolism ; Phosphatidylinositols/metabolism ; Point Mutation ; Protein Conformation ; Protein Structure, Secondary ; Protein Structure, Tertiary ; Pyridines/chemistry/metabolism/pharmacology ; Pyrimidines/chemistry/metabolism/pharmacology
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  • 86
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    American Association for the Advancement of Science (AAAS)
    Publication Date: 2010-07-24
    Description: 〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Stone, Richard -- New York, N.Y. -- Science. 2010 Jul 23;329(5990):378. doi: 10.1126/science.329.5990.378.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/20651127" target="_blank"〉PubMed〈/a〉
    Keywords: Animals ; China ; *Conservation of Natural Resources ; *Ecosystem ; *Endangered Species ; Extinction, Biological ; Female ; Fisheries ; *Fishes ; Human Activities ; Humans ; Male ; Population Dynamics ; *Porpoises ; *Rivers
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  • 87
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    American Association for the Advancement of Science (AAAS)
    Publication Date: 2010-10-30
    Description: 〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Mindell, Joseph A -- New York, N.Y. -- Science. 2010 Oct 29;330(6004):601-2. doi: 10.1126/science.1198306.〈br /〉〈span class="detail_caption"〉Author address: 〈/span〉Membrane Transport Biophysics Section, Porter Neuroscience Research Center, National Institute of Neurological Disorders and Stroke, National Institutes of Health, Bethesda, MD 20892, USA. mindellj@ninds.nih.gov〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/21030639" target="_blank"〉PubMed〈/a〉
    Keywords: Algal Proteins/*chemistry/metabolism ; Antiporters/*chemistry/metabolism ; Binding Sites ; Chloride Channels/*chemistry/metabolism ; Chlorides/*metabolism ; Crystallization ; Crystallography, X-Ray ; Cytoplasm/chemistry ; Eukaryota/*chemistry ; Glutamic Acid/metabolism ; Ion Channel Gating ; Ion Transport ; Models, Molecular ; Protein Structure, Tertiary ; Protons
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  • 88
    Publication Date: 2010-03-20
    Description: 〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Xin, Hao -- Stone, Richard -- New York, N.Y. -- Science. 2010 Mar 19;327(5972):1440-1. doi: 10.1126/science.327.5972.1440-a.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/20299561" target="_blank"〉PubMed〈/a〉
    Keywords: *Budgets ; China ; Conservation of Natural Resources/*economics ; *Ecosystem ; Energy-Generating Resources ; Environmental Pollution/*prevention & control ; Financing, Government
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  • 89
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    American Association for the Advancement of Science (AAAS)
    Publication Date: 2010-06-19
    Description: 〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Stone, Richard -- New York, N.Y. -- Science. 2010 Jun 18;328(5985):1476-7. doi: 10.1126/science.328.5985.1476.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/20558685" target="_blank"〉PubMed〈/a〉
    Keywords: Bacteria/*metabolism ; Carbon/analysis/*metabolism ; Carbon Dioxide/*metabolism ; Ecological and Environmental Processes ; *Ecosystem ; Organic Chemicals/analysis/*metabolism ; Organic Chemistry Processes ; Phytoplankton/growth & development/metabolism ; Seawater/*chemistry/*microbiology
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  • 90
    Publication Date: 2010-02-06
    Description: The bacterial flagellar switch that controls the direction of flagellar rotation during chemotaxis has a highly cooperative response. This has previously been understood in terms of the classic two-state, concerted model of allosteric regulation. Here, we used high-resolution optical microscopy to observe switching of single motors and uncover the stochastic multistate nature of the switch. Our observations are in detailed quantitative agreement with a recent general model of allosteric cooperativity that exhibits conformational spread--the stochastic growth and shrinkage of domains of adjacent subunits sharing a particular conformational state. We expect that conformational spread will be important in explaining cooperativity in other large signaling complexes.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Bai, Fan -- Branch, Richard W -- Nicolau, Dan V Jr -- Pilizota, Teuta -- Steel, Bradley C -- Maini, Philip K -- Berry, Richard M -- BB/E00458X/1/Biotechnology and Biological Sciences Research Council/United Kingdom -- BB/H01991X/1/Biotechnology and Biological Sciences Research Council/United Kingdom -- New York, N.Y. -- Science. 2010 Feb 5;327(5966):685-9. doi: 10.1126/science.1182105.〈br /〉〈span class="detail_caption"〉Author address: 〈/span〉Clarendon Laboratory, Department of Physics, University of Oxford, Parks Road, Oxford OX1 3PU, UK.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/20133571" target="_blank"〉PubMed〈/a〉
    Keywords: Allosteric Regulation ; Bacterial Proteins/chemistry/metabolism ; Binding Sites ; Escherichia coli/metabolism ; Escherichia coli Proteins/*chemistry/*metabolism ; Flagella/*chemistry ; Membrane Proteins/chemistry/metabolism ; Models, Biological ; Models, Molecular ; Molecular Motor Proteins/*chemistry/*metabolism ; Monte Carlo Method ; Protein Binding ; Protein Conformation ; Protein Subunits/*chemistry/*metabolism ; Signal Transduction ; Thermodynamics
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  • 91
    Publication Date: 2010-01-02
    Description: 〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Jansen, Patrick A -- Muller-Landau, Helene C -- Wright, S Joseph -- New York, N.Y. -- Science. 2010 Jan 1;327(5961):30. doi: 10.1126/science.327.5961.30-a.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/20044556" target="_blank"〉PubMed〈/a〉
    Keywords: Animals ; Biodiversity ; *Carbon ; *Climatic Processes ; *Ecosystem ; *Meat ; *Trees ; Tropical Climate ; *Vertebrates
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  • 92
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    American Association for the Advancement of Science (AAAS)
    Publication Date: 2010-02-06
    Description: 〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Lehmann, Caroline E R -- New York, N.Y. -- Science. 2010 Feb 5;327(5966):642-3. doi: 10.1126/science.327.5966.642-c.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/20133552" target="_blank"〉PubMed〈/a〉
    Keywords: Animals ; Biodiversity ; *Conservation of Natural Resources ; *Ecosystem
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  • 93
    Publication Date: 2010-05-29
    Description: High-conductance voltage- and Ca2+-activated K+ (BK) channels encode negative feedback regulation of membrane voltage and Ca2+ signaling, playing a central role in numerous physiological processes. We determined the x-ray structure of the human BK Ca2+ gating apparatus at a resolution of 3.0 angstroms and deduced its tetrameric assembly by solving a 6 angstrom resolution structure of a Na+-activated homolog. Two tandem C-terminal regulator of K+ conductance (RCK) domains from each of four channel subunits form a 350-kilodalton gating ring at the intracellular membrane surface. A sequence of aspartic amino acids that is known as the Ca2+ bowl, and is located within the second of the tandem RCK domains, creates four Ca2+ binding sites on the outer perimeter of the gating ring at the "assembly interface" between RCK domains. Functionally important mutations cluster near the Ca2+ bowl, near the "flexible interface" between RCK domains, and on the surface of the gating ring that faces the voltage sensors. The structure suggests that the Ca2+ gating ring, in addition to regulating the pore directly, may also modulate the voltage sensor.〈br /〉〈br /〉〈a href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3022345/" target="_blank"〉〈img src="https://static.pubmed.gov/portal/portal3rc.fcgi/4089621/img/3977009" border="0"〉〈/a〉   〈a href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3022345/" target="_blank"〉This paper as free author manuscript - peer-reviewed and accepted for publication〈/a〉〈br /〉〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Yuan, Peng -- Leonetti, Manuel D -- Pico, Alexander R -- Hsiung, Yichun -- MacKinnon, Roderick -- P30 EB009998/EB/NIBIB NIH HHS/ -- R01 GM043949/GM/NIGMS NIH HHS/ -- R01 GM043949-20/GM/NIGMS NIH HHS/ -- Howard Hughes Medical Institute/ -- New York, N.Y. -- Science. 2010 Jul 9;329(5988):182-6. doi: 10.1126/science.1190414. Epub 2010 May 27.〈br /〉〈span class="detail_caption"〉Author address: 〈/span〉Laboratory of Molecular Neurobiology and Biophysics, Rockefeller University, Howard Hughes Medical Institute, 1230 York Avenue, New York, NY 10065, USA.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/20508092" target="_blank"〉PubMed〈/a〉
    Keywords: Amino Acid Sequence ; Binding Sites ; Calcium/*metabolism ; Crystallography, X-Ray ; Humans ; *Ion Channel Gating ; Large-Conductance Calcium-Activated Potassium Channel alpha ; Subunits/*chemistry/genetics/*metabolism ; Ligands ; Models, Molecular ; Molecular Sequence Data ; Mutant Proteins/chemistry/metabolism ; Patch-Clamp Techniques ; Protein Conformation ; Protein Folding ; Protein Structure, Quaternary ; Protein Structure, Secondary ; Protein Structure, Tertiary ; Protein Subunits/chemistry ; Sodium/metabolism
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  • 94
    Publication Date: 2010-10-12
    Description: CLC proteins transport chloride (Cl(-)) ions across cell membranes to control the electrical potential of muscle cells, transfer electrolytes across epithelia, and control the pH and electrolyte composition of intracellular organelles. Some members of this protein family are Cl(-) ion channels, whereas others are secondary active transporters that exchange Cl(-) ions and protons (H(+)) with a 2:1 stoichiometry. We have determined the structure of a eukaryotic CLC transporter at 3.5 angstrom resolution. Cytoplasmic cystathionine beta-synthase (CBS) domains are strategically positioned to regulate the ion-transport pathway, and many disease-causing mutations in human CLCs reside on the CBS-transmembrane interface. Comparison with prokaryotic CLC shows that a gating glutamate residue changes conformation and suggests a basis for 2:1 Cl(-)/H(+) exchange and a simple mechanistic connection between CLC channels and transporters.〈br /〉〈br /〉〈a href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3079386/" target="_blank"〉〈img src="https://static.pubmed.gov/portal/portal3rc.fcgi/4089621/img/3977009" border="0"〉〈/a〉   〈a href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3079386/" target="_blank"〉This paper as free author manuscript - peer-reviewed and accepted for publication〈/a〉〈br /〉〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Feng, Liang -- Campbell, Ernest B -- Hsiung, Yichun -- MacKinnon, Roderick -- P30 EB009998/EB/NIBIB NIH HHS/ -- R01 GM043949/GM/NIGMS NIH HHS/ -- R01 GM043949-20/GM/NIGMS NIH HHS/ -- R01 GM043949-21/GM/NIGMS NIH HHS/ -- Howard Hughes Medical Institute/ -- New York, N.Y. -- Science. 2010 Oct 29;330(6004):635-41. doi: 10.1126/science.1195230. Epub 2010 Sep 30.〈br /〉〈span class="detail_caption"〉Author address: 〈/span〉Laboratory of Molecular Neurobiology and Biophysics, Rockefeller University, Howard Hughes Medical Institute, 1230 York Avenue, New York, NY 10065, USA.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/20929736" target="_blank"〉PubMed〈/a〉
    Keywords: Algal Proteins/chemistry/metabolism ; Animals ; Antiporters/*chemistry/metabolism ; Binding Sites ; Cell Line ; Cell Membrane/chemistry ; Chloride Channels/*chemistry/metabolism ; Chlorides/*metabolism ; Crystallization ; Crystallography, X-Ray ; Cystathionine beta-Synthase/chemistry ; Cytoplasm/chemistry ; Glutamic Acid/metabolism ; Ion Channel Gating ; Ion Transport ; Models, Biological ; Models, Molecular ; Protein Conformation ; Protein Multimerization ; Protein Structure, Secondary ; Protein Structure, Tertiary ; Protein Subunits/chemistry ; Protons ; Rhodophyta/*chemistry/metabolism
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    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
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  • 95
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    American Association for the Advancement of Science (AAAS)
    Publication Date: 2010-07-22
    Description: 〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Swaisgood, Ronald R -- Terborgh, John W -- Blumstein, Daniel T -- New York, N.Y. -- Science. 2010 Jul 16;329(5989):276. doi: 10.1126/science.329.5989.276-a.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/20647447" target="_blank"〉PubMed〈/a〉
    Keywords: Animals ; Behavioral Research/*economics ; *Ecosystem ; Research/*economics ; *Research Support as Topic ; Time Factors
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    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
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  • 96
    Publication Date: 2010-05-29
    Description: 〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Barrett, Meredith A -- Brown, Jason L -- Morikawa, Megan K -- Labat, Jean-Noel -- Yoder, Anne D -- New York, N.Y. -- Science. 2010 May 28;328(5982):1109-10. doi: 10.1126/science.1187740.〈br /〉〈span class="detail_caption"〉Author address: 〈/span〉University Program in Ecology, Duke University, Durham, NC 27708, USA. meredith.barrett@duke.edu〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/20508116" target="_blank"〉PubMed〈/a〉
    Keywords: Biodiversity ; *Commerce ; *Conservation of Natural Resources ; *Dalbergia ; *Ecosystem ; *Endangered Species ; Industry ; *International Cooperation ; Madagascar ; *Trees ; Wood/economics
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
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  • 97
    Publication Date: 2010-02-27
    Description: Spatial diversity gradients are a pervasive feature of life on Earth. We examined a global ocean circulation, biogeochemistry, and ecosystem model that indicated a decrease in phytoplankton diversity with increasing latitude, consistent with observations of many marine and terrestrial taxa. In the modeled subpolar oceans, seasonal variability of the environment led to competitive exclusion of phytoplankton with slower growth rates and lower diversity. The relatively weak seasonality of the stable subtropical and tropical oceans in the global model enabled long exclusion time scales and prolonged coexistence of multiple phytoplankton with comparable fitness. Superimposed on the decline in diversity seen from equator to pole were "hot spots" of enhanced diversity in some regions of energetic ocean circulation, which reflected lateral dispersal.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Barton, Andrew D -- Dutkiewicz, Stephanie -- Flierl, Glenn -- Bragg, Jason -- Follows, Michael J -- New York, N.Y. -- Science. 2010 Mar 19;327(5972):1509-11. doi: 10.1126/science.1184961. Epub 2010 Feb 25.〈br /〉〈span class="detail_caption"〉Author address: 〈/span〉Department of Earth, Atmospheric, and Planetary Sciences, Massachusetts Institute of Technology, 77 Massachusetts Avenue, Cambridge, MA 02139, USA. adbarton@mit.edu〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/20185684" target="_blank"〉PubMed〈/a〉
    Keywords: *Biodiversity ; Biomass ; Climate ; *Ecosystem ; Environment ; Geography ; Models, Biological ; Oceans and Seas ; *Phytoplankton/growth & development/physiology ; Population Dynamics ; Seasons ; *Seawater
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    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
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  • 98
    Publication Date: 2010-02-20
    Description: Large-bodied suspension feeders (planktivores), which include the most massive animals to have ever lived, are conspicuously absent from Mesozoic marine environments. The only clear representatives of this trophic guild in the Mesozoic have been an enigmatic and apparently short-lived Jurassic group of extinct pachycormid fishes. Here, we report several new examples of these giant bony fishes from Asia, Europe, and North America. These fossils provide the first detailed anatomical information on this poorly understood clade and extend its range from the lower Middle Jurassic to the end of the Cretaceous, showing that this group persisted for more than 100 million years. Modern large-bodied, planktivorous vertebrates diversified after the extinction of pachycormids at the Cretaceous-Paleogene boundary, which is consistent with an opportunistic refilling of vacated ecospace.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Friedman, Matt -- Shimada, Kenshu -- Martin, Larry D -- Everhart, Michael J -- Liston, Jeff -- Maltese, Anthony -- Triebold, Michael -- New York, N.Y. -- Science. 2010 Feb 19;327(5968):990-3. doi: 10.1126/science.1184743.〈br /〉〈span class="detail_caption"〉Author address: 〈/span〉University of Chicago, 1025 East 57th Street, Chicago, IL 60637, USA. mattf@earth.ox.ac.uk [corrected]〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/20167784" target="_blank"〉PubMed〈/a〉
    Keywords: Animals ; Asia ; Biological Evolution ; Body Size ; Bone and Bones/anatomy & histology ; *Ecosystem ; Europe ; Extinction, Biological ; Feeding Behavior ; *Fishes/anatomy & histology/classification/physiology ; Fossils ; Jaw/anatomy & histology ; North America ; Oceans and Seas ; Phylogeny ; *Plankton ; *Seawater ; Skull/anatomy & histology ; Time
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    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
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  • 99
    Publication Date: 2010-04-03
    Description: Voltage sensors regulate the conformations of voltage-dependent ion channels and enzymes. Their nearly switchlike response as a function of membrane voltage comes from the movement of positively charged amino acids, arginine or lysine, across the membrane field. We used mutations with natural and unnatural amino acids, electrophysiological recordings, and x-ray crystallography to identify a charge transfer center in voltage sensors that facilitates this movement. This center consists of a rigid cyclic "cap" and two negatively charged amino acids to interact with a positive charge. Specific mutations induce a preference for lysine relative to arginine. By placing lysine at specific locations, the voltage sensor can be stabilized in different conformations, which enables a dissection of voltage sensor movements and their relation to ion channel opening.〈br /〉〈br /〉〈a href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2869078/" target="_blank"〉〈img src="https://static.pubmed.gov/portal/portal3rc.fcgi/4089621/img/3977009" border="0"〉〈/a〉   〈a href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2869078/" target="_blank"〉This paper as free author manuscript - peer-reviewed and accepted for publication〈/a〉〈br /〉〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Tao, Xiao -- Lee, Alice -- Limapichat, Walrati -- Dougherty, Dennis A -- MacKinnon, Roderick -- GM43949/GM/NIGMS NIH HHS/ -- NS 34407/NS/NINDS NIH HHS/ -- P30 EB009998/EB/NIBIB NIH HHS/ -- R01 GM043949/GM/NIGMS NIH HHS/ -- R01 GM043949-20/GM/NIGMS NIH HHS/ -- R37 NS034407/NS/NINDS NIH HHS/ -- R37 NS034407-15/NS/NINDS NIH HHS/ -- R37 NS034407-15S1/NS/NINDS NIH HHS/ -- Howard Hughes Medical Institute/ -- New York, N.Y. -- Science. 2010 Apr 2;328(5974):67-73. doi: 10.1126/science.1185954.〈br /〉〈span class="detail_caption"〉Author address: 〈/span〉Laboratory of Molecular Neurobiology and Biophysics, Rockefeller University, Howard Hughes Medical Institute, 1230 York Avenue, New York, NY 10065, USA.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/20360102" target="_blank"〉PubMed〈/a〉
    Keywords: Amino Acid Sequence ; Amino Acid Substitution ; Animals ; Arginine/chemistry ; Binding Sites ; Crystallography, X-Ray ; Electric Capacitance ; *Ion Channel Gating ; Kv1.2 Potassium Channel/*chemistry/*metabolism ; Lysine/chemistry ; Models, Molecular ; Molecular Sequence Data ; Patch-Clamp Techniques ; Phenylalanine/chemistry ; Protein Conformation ; Rats ; Recombinant Fusion Proteins/chemistry/metabolism ; Shab Potassium Channels/*chemistry/*metabolism ; Shaker Superfamily of Potassium Channels/chemistry/metabolism ; Tryptophan/chemistry ; Xenopus laevis
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    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
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  • 100
    Publication Date: 2010-12-24
    Description: To gain insight into how genomic information is translated into cellular and developmental programs, the Drosophila model organism Encyclopedia of DNA Elements (modENCODE) project is comprehensively mapping transcripts, histone modifications, chromosomal proteins, transcription factors, replication proteins and intermediates, and nucleosome properties across a developmental time course and in multiple cell lines. We have generated more than 700 data sets and discovered protein-coding, noncoding, RNA regulatory, replication, and chromatin elements, more than tripling the annotated portion of the Drosophila genome. Correlated activity patterns of these elements reveal a functional regulatory network, which predicts putative new functions for genes, reveals stage- and tissue-specific regulators, and enables gene-expression prediction. Our results provide a foundation for directed experimental and computational studies in Drosophila and related species and also a model for systematic data integration toward comprehensive genomic and functional annotation.〈br /〉〈br /〉〈a href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3192495/" target="_blank"〉〈img src="https://static.pubmed.gov/portal/portal3rc.fcgi/4089621/img/3977009" border="0"〉〈/a〉   〈a href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3192495/" target="_blank"〉This paper as free author manuscript - peer-reviewed and accepted for publication〈/a〉〈br /〉〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉modENCODE Consortium -- Roy, Sushmita -- Ernst, Jason -- Kharchenko, Peter V -- Kheradpour, Pouya -- Negre, Nicolas -- Eaton, Matthew L -- Landolin, Jane M -- Bristow, Christopher A -- Ma, Lijia -- Lin, Michael F -- Washietl, Stefan -- Arshinoff, Bradley I -- Ay, Ferhat -- Meyer, Patrick E -- Robine, Nicolas -- Washington, Nicole L -- Di Stefano, Luisa -- Berezikov, Eugene -- Brown, Christopher D -- Candeias, Rogerio -- Carlson, Joseph W -- Carr, Adrian -- Jungreis, Irwin -- Marbach, Daniel -- Sealfon, Rachel -- Tolstorukov, Michael Y -- Will, Sebastian -- Alekseyenko, Artyom A -- Artieri, Carlo -- Booth, Benjamin W -- Brooks, Angela N -- Dai, Qi -- Davis, Carrie A -- Duff, Michael O -- Feng, Xin -- Gorchakov, Andrey A -- Gu, Tingting -- Henikoff, Jorja G -- Kapranov, Philipp -- Li, Renhua -- MacAlpine, Heather K -- Malone, John -- Minoda, Aki -- Nordman, Jared -- Okamura, Katsutomo -- Perry, Marc -- Powell, Sara K -- Riddle, Nicole C -- Sakai, Akiko -- Samsonova, Anastasia -- Sandler, Jeremy E -- Schwartz, Yuri B -- Sher, Noa -- Spokony, Rebecca -- Sturgill, David -- van Baren, Marijke -- Wan, Kenneth H -- Yang, Li -- Yu, Charles -- Feingold, Elise -- Good, Peter -- Guyer, Mark -- Lowdon, Rebecca -- Ahmad, Kami -- Andrews, Justen -- Berger, Bonnie -- Brenner, Steven E -- Brent, Michael R -- Cherbas, Lucy -- Elgin, Sarah C R -- Gingeras, Thomas R -- Grossman, Robert -- Hoskins, Roger A -- Kaufman, Thomas C -- Kent, William -- Kuroda, Mitzi I -- Orr-Weaver, Terry -- Perrimon, Norbert -- Pirrotta, Vincenzo -- Posakony, James W -- Ren, Bing -- Russell, Steven -- Cherbas, Peter -- Graveley, Brenton R -- Lewis, Suzanna -- Micklem, Gos -- Oliver, Brian -- Park, Peter J -- Celniker, Susan E -- Henikoff, Steven -- Karpen, Gary H -- Lai, Eric C -- MacAlpine, David M -- Stein, Lincoln D -- White, Kevin P -- Kellis, Manolis -- R01 HG004037/HG/NHGRI NIH HHS/ -- R01HG004037/HG/NHGRI NIH HHS/ -- RC2HG005639/HG/NHGRI NIH HHS/ -- U01 HG004258/HG/NHGRI NIH HHS/ -- U01 HG004271/HG/NHGRI NIH HHS/ -- U01 HG004279/HG/NHGRI NIH HHS/ -- U01HG004258/HG/NHGRI NIH HHS/ -- U01HG004261/HG/NHGRI NIH HHS/ -- U01HG004264/HG/NHGRI NIH HHS/ -- U01HG004271/HG/NHGRI NIH HHS/ -- U01HG004274/HG/NHGRI NIH HHS/ -- U01HG004279/HG/NHGRI NIH HHS/ -- U41HG004269/HG/NHGRI NIH HHS/ -- ZIA DK015600-14/Intramural NIH HHS/ -- Howard Hughes Medical Institute/ -- New York, N.Y. -- Science. 2010 Dec 24;330(6012):1787-97. doi: 10.1126/science.1198374. Epub 2010 Dec 22.〈br /〉〈span class="detail_caption"〉Author address: 〈/span〉Computer Science and Artificial Intelligence Laboratory, Massachusetts Institute of Technology (MIT), Cambridge, MA 02139, USA.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/21177974" target="_blank"〉PubMed〈/a〉
    Keywords: Animals ; Binding Sites ; *Chromatin/genetics/metabolism ; Computational Biology/methods ; Drosophila Proteins/genetics/metabolism ; Drosophila melanogaster/*genetics/growth & development/metabolism ; Epigenesis, Genetic ; Gene Expression Regulation ; *Gene Regulatory Networks ; Genes, Insect ; *Genome, Insect ; Genomics/methods ; Histones/metabolism ; *Molecular Sequence Annotation ; Nucleosomes/genetics/metabolism ; Promoter Regions, Genetic ; RNA, Small Untranslated/genetics/metabolism ; Transcription Factors/metabolism ; Transcription, Genetic
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    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
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