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  • Chemistry  (44,126)
  • ASTRONOMY  (1,733)
  • Biochemistry and Biotechnology  (1,710)
  • 1980-1984  (35,448)
  • 1925-1929
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Keywords
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  • 1
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    Rational approaches to chemotherapy: antisickling agents (1981)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1981-08-14
    Description: 〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Klotz, I M -- Haney, D N -- King, L C -- New York, N.Y. -- Science. 1981 Aug 14;213(4509):724-31.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/7256275" target="_blank"〉PubMed〈/a〉
    Keywords: Anemia, Sickle Cell/*drug therapy ; Aspirin/analogs & derivatives/therapeutic use ; Chemical Phenomena ; Chemistry ; *Hemoglobin, Sickle ; Humans ; Protein Binding/drug effects ; Protein Conformation ; Salicylates/*therapeutic use ; Solubility ; Structure-Activity Relationship
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
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  • 2
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    Alpha-substituted gamma-butyrolactones: new class of anticonvulsant drugs (1982)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1982-09-10
    Description: Alkyl-Substituted gamma-butyrolactones were synthesized and tested for their convulsant and anticonvulsant actions in mice and guinea pigs. The alpha-substituted compounds, alpha, alpha-dimethyl-, and alpha-ethyl-alpha-methyl-gamma-butyrolactone were anticonvulsant compounds with a spectrum of activity similar to that of ethosuximide. In contrast, beta-substituted compounds were convulsant agents similar to picrotoxinin. The alpha-substituted-gama-butyrolactones represent a new class of anticonvulsant drug with experimental and clinical potential.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Klunk, W E -- McKeon, A -- Covey, D F -- Ferrendelli, J A -- GM-07200/GM/NIGMS NIH HHS/ -- GM-24483/GM/NIGMS NIH HHS/ -- NS-14834/NS/NINDS NIH HHS/ -- etc. -- New York, N.Y. -- Science. 1982 Sep 10;217(4564):1040-2.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/6810462" target="_blank"〉PubMed〈/a〉
    Keywords: *4-Butyrolactone/analogs & derivatives/*therapeutic use/toxicity ; Animals ; *Anticonvulsants ; Chemical Phenomena ; Chemistry ; Convulsants ; Drug Evaluation, Preclinical ; Electroencephalography ; Epilepsy, Absence/drug therapy ; Ethosuximide/pharmacology ; *Furans/*therapeutic use ; Guinea Pigs ; Mice ; Structure-Activity Relationship ; Trimethadione/pharmacology
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  • 3
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    Phase transition and crystal structure of the 37 degrees C form of cholesterol (1983)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1983-05-06
    Description: Crystalline cholesterol undergoes a phase transition a few degrees below human body temperature. The high-temperature form has an unusually complex structure with 16 independent molecules. In the transition two molecules change side chain conformation, four reorient about their long axes, and ten remain unchanged. The transition mechanism implies relatively nonspecific intermolecular interactions, qualitatively consistent with the behavior of cholesterol in biomembranes. The transition preserves a remarkably closely obeyed pseudosymmetry present in the structure.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Hsu, L Y -- Nordman, C E -- GM15259/GM/NIGMS NIH HHS/ -- New York, N.Y. -- Science. 1983 May 6;220(4597):604-6.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/6836303" target="_blank"〉PubMed〈/a〉
    Keywords: Body Temperature ; Chemical Phenomena ; Chemistry ; *Cholesterol ; Crystallization ; Humans ; Magnetic Resonance Spectroscopy ; Molecular Conformation
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  • 4
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    Cytochrome a3 structure in carbon monoxide-bound cytochrome oxidase (1984)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1984-07-20
    Description: The iron-carbon monoxide stretching mode and the iron-carbon-oxygen bending mode in carbon monoxide-bound cytochrome oxidase have been assigned at 520 and 578 cm-1, respectively. The frequencies, widths, and intensities of these modes show that the Fe-C-O grouping in carbon monoxide-cytochrome a3 is linear but tilted from the normal to the heme plane; that the iron-histidine bond in both five- and six-coordinate cytochrome a3 is strained; and that the carbon monoxide and the proximal histidine each have characteristic, well-defined orientations in all molecules. These data can account for the binding affinities of carbon monoxide and dioxygen under physiological conditions.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Argade, P V -- Ching, Y C -- Rousseau, D L -- New York, N.Y. -- Science. 1984 Jul 20;225(4659):329-31.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/6330890" target="_blank"〉PubMed〈/a〉
    Keywords: Animals ; Carbon Monoxide/metabolism ; Cattle ; Chemical Phenomena ; Chemistry ; Electron Transport Complex IV/*metabolism ; Myoglobin/metabolism ; Oxidation-Reduction ; Oxygen/metabolism ; Spectrum Analysis, Raman
    Print ISSN: 0036-8075
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  • 5
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    Leukotrienes: mediators of immediate hypersensitivity reactions and inflammation (1983)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1983-05-06
    Description: Arachidonic acid plays a central role in a biological control system where such oxygenated derivatives as prostaglandins, thromboxanes, and leukotrienes are mediators. The leukotrienes are formed by transformation of arachidonic acid into an unstable epoxide intermediate, leukotriene A4, which can be converted enzymatically by hydration to leukotriene B4, and by addition of glutathione to leukotriene C4. This last compound is metabolized to leukotrienes D4 and E4 by successive elimination of a gamma-glutamyl residue and glycine. Slow-reacting substance of anaphylaxis consists of leukotrienes C4, D4, and E4. The cysteinyl-containing leukotrienes are potent bronchoconstrictors, increase vascular permeability in postcapillary venules, and stimulate mucus secretion. Leukotriene B4 causes adhesion and chemotactic movement of leukocytes and stimulates aggregation, enzyme release, and generation of superoxide in neutrophils. Leukotrienes C4, D4, and E4, which are released from the lung tissue of asthmatic subjects exposed to specific allergens, seem to play a pathophysiological role in immediate hypersensitivity reactions. These leukotrienes, as well as leukotriene B4, have pro-inflammatory effects.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Samuelsson, B -- New York, N.Y. -- Science. 1983 May 6;220(4597):568-75.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/6301011" target="_blank"〉PubMed〈/a〉
    Keywords: Animals ; Arachidonic Acids/metabolism/pharmacology/physiology ; Bronchi/drug effects ; Cats ; Chemical Phenomena ; Chemistry ; Cricetinae ; Guinea Pigs ; Haplorhini ; Humans ; Hypersensitivity, Immediate/*physiopathology ; Inflammation/*physiopathology ; Leukocytes/drug effects/metabolism ; Leukotriene B4/pharmacology/*physiology ; Mice ; Microcirculation/drug effects ; Rabbits ; Rats ; SRS-A/*physiology
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  • 6
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    Amphiphilic secondary structure: design of peptide hormones (1984)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1984-01-20
    Description: Peptide synthesis can be used for elucidating the roles of secondary structures in the specificity of hormones, antigens, and toxins. Intermediate sized peptides with these activities assume amphiphilic secondary structures in the presence of membranes. When models are designed to optimize the amphiphilicity of the secondary structure, stronger interactions can be observed with the synthetic peptides than with the naturally occurring analogs.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Kaiser, E T -- Kezdy, F J -- HL-18577/HL/NHLBI NIH HHS/ -- New York, N.Y. -- Science. 1984 Jan 20;223(4633):249-55.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/6322295" target="_blank"〉PubMed〈/a〉
    Keywords: Amino Acid Sequence ; Apolipoprotein A-I ; Apolipoproteins ; Binding Sites ; Calcitonin ; Chemical Phenomena ; Chemistry ; Corticotropin-Releasing Hormone ; Endorphins ; Glucagon ; Growth Hormone-Releasing Hormone ; *Hormones/pharmacology ; Lipoproteins, HDL ; Melitten ; Models, Structural ; *Peptides/chemical synthesis/metabolism/pharmacology ; Protein Conformation ; Structure-Activity Relationship ; beta-Endorphin
    Print ISSN: 0036-8075
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  • 7
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    Fourier transform mass spectrometry (1984)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1984-10-19
    Description: Fourier transform mass spectrometry will play an important role in the future because of its unique combination of high mass resolution, high upper mass limit, and multichannel advantage. These features have already found application in gas chromatography-mass spectrometry, multiphoton ionization, laser desorption, and secondary ion mass spectrometry. However, its most notable feature is the ability to store ions. This characteristic, when combined with the others, will allow expeditious study of the interaction of gas-phase ions with both photons (photodissociation) and neutral molecules, and the convenient application of this fundamental information for chemical analysis.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Gross, M L -- Rempel, D L -- 2-8423576/PHS HHS/ -- New York, N.Y. -- Science. 1984 Oct 19;226(4672):261-8.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/6385250" target="_blank"〉PubMed〈/a〉
    Keywords: Chemical Phenomena ; Chemistry ; *Fourier Analysis ; Ions ; Lasers ; *Mass Spectrometry/instrumentation/methods
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  • 8
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    Studying enzyme mechanism by 13C nuclear magnetic resonance (1984)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1984-08-31
    Description: High-resolution carbon-13 nuclear magnetic resonance (NMR) spectra of enzyme-inhibitor and enzyme-substrate complexes provide detailed structural and stereochemical information on the mechanism of enzyme action. The proteases trypsin and papain are shown to form tetrahedrally coordinated complexes and acyl derivatives with a variety of compounds artificially enriched at the site or sites of interest. These results are compared with the structural information derived from x-ray diffraction. Detailed NMR studies have provided a clearer picture of the ionization state of the residues participating in enzyme-catalyzed processes than other more classical techniques. The dynamics of enzymic catalysis can be observed at sub-zero temperatures by a combination of cryoenzymology and carbon-13 NMR spectroscopy. With these powerful techniques, transient, covalently bound intermediates in enzyme-catalyzed reactions can be detected and their structures rigorously assigned.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Mackenzie, N E -- Malthouse, J P -- Scott, A I -- New York, N.Y. -- Science. 1984 Aug 31;225(4665):883-9.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/6433481" target="_blank"〉PubMed〈/a〉
    Keywords: Binding Sites ; Carbon Isotopes ; Carboxypeptidases/metabolism ; Carboxypeptidases A ; Catalysis ; Chemical Phenomena ; Chemistry ; Coenzymes/*metabolism ; Endopeptidases/metabolism ; Enzymes/*metabolism ; Freezing ; Fructose-Bisphosphate Aldolase/metabolism ; Magnetic Resonance Spectroscopy ; Papain/metabolism ; Pepsin A/metabolism ; Peptide Hydrolases/*metabolism ; Protease Inhibitors ; Pterins/metabolism ; Pyridoxal Phosphate/metabolism ; Serine Endopeptidases
    Print ISSN: 0036-8075
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  • 9
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    What is the risk from chlorofluorocarbons? (1984)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1984-03-09
    Description: 〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Maugh, T H 2nd -- New York, N.Y. -- Science. 1984 Mar 9;223(4640):1051-2.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/6695193" target="_blank"〉PubMed〈/a〉
    Keywords: *Air Pollutants ; *Atmosphere ; Carbon Tetrachloride ; Chemical Phenomena ; Chemistry ; *Chlorofluorocarbons, Methane ; Free Radicals ; Nitrogen Dioxide ; Nitrous Oxide ; Oxygen ; *Ozone ; Photochemistry ; Risk ; Singlet Oxygen ; Trichloroethanes ; Ultraviolet Rays
    Print ISSN: 0036-8075
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    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
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  • 10
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    Pyrolysis mass spectrometry of complex organic materials (1984)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1984-10-19
    Description: Pyrolysis mass spectrometry in combination with computerized multivariate statistical analysis enables qualitative and quantitative analysis of nonvolatile organic materials containing molecular assemblies of a complexity and size far beyond the capabilities of direct mass spectrometry. The state of the art in pyrolysis mass spectrometry techniques is illustrated through specific applications, including structural determination and quality control of synthetic polymers, quantitative analysis of polymer mixtures, classification and structural characterization of fossil organic matter, and nonsupervised numerical extraction of component patterns from complex biological samples.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Meuzelaar, H L -- Windig, W -- Harper, A M -- Huff, S M -- McClennen, W H -- Richards, J M -- New York, N.Y. -- Science. 1984 Oct 19;226(4672):268-74.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/6484572" target="_blank"〉PubMed〈/a〉
    Keywords: Biochemical Phenomena ; Biochemistry ; Chemical Phenomena ; Chemistry ; Coal ; Enterobacteriaceae/analysis/isolation & purification ; Hot Temperature ; Mass Spectrometry/*methods ; Polymers
    Print ISSN: 0036-8075
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  • 11
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    Lariat RNA's as intermediates and products in the splicing of messenger RNA precursors (1984)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1984-08-31
    Description: The splicing of messenger RNA precursors in vitro proceeds through an intermediate that has the 5' end of the intervening sequence joined to a site near the 3' splice site. This lariat structure, which has been characterized for an adenovirus 2 major late transcript, has a branch point, with 2'-5' and 3'-5' phosphodiester bonds emanating from a single adenosine residue. The excised intervening sequence retains the branch site and terminates in a guanosine residue with a 3' hydroxyl group. The phosphate group at the splice junction between the two exons originates from the 3' splice site at the precursor.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Padgett, R A -- Konarska, M M -- Grabowski, P J -- Hardy, S F -- Sharp, P A -- P01-CA14051/CA/NCI NIH HHS/ -- P01-CA26717/CA/NCI NIH HHS/ -- R01-GM32467/GM/NIGMS NIH HHS/ -- New York, N.Y. -- Science. 1984 Aug 31;225(4665):898-903.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/6206566" target="_blank"〉PubMed〈/a〉
    Keywords: Adenoviruses, Human/metabolism ; Base Sequence ; Chemical Phenomena ; Chemistry ; Nucleic Acid Conformation ; Nucleic Acid Precursors/analysis/*metabolism ; Oligoribonucleotides/metabolism ; Phosphates/metabolism ; RNA/analysis/*metabolism ; RNA Precursors ; *RNA Splicing ; RNA, Messenger/analysis/*metabolism ; RNA, Viral/analysis/*metabolism
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  • 12
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    beta-Carotene: an unusual type of lipid antioxidant (1984)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1984-05-11
    Description: The mechanism of lipid peroxidation and the manner in which antioxidants function is reviewed. beta-Carotene is a purported anticancer agent, which is believed by some to have antioxidant action of a radical-trapping type. However, definitive experimental support for such action has been lacking. New experiments in vitro show that beta-carotene belongs to a previously unknown class of biological antioxidants. Specifically, it exhibits good radical-trapping antioxidant behavior only at partial pressures of oxygen significantly less than 150 torr, the pressure of oxygen in normal air. Such low oxygen partial pressures are found in most tissues under physiological conditions. At higher oxygen pressures, beta-carotene loses its antioxidant activity and shows an autocatalytic, prooxidant effect, particularly at relatively high concentrations. Similar oxygen-pressure-dependent behavior may be shown by other compounds containing many conjugated double bonds.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Burton, G W -- Ingold, K U -- New York, N.Y. -- Science. 1984 May 11;224(4649):569-73.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/6710156" target="_blank"〉PubMed〈/a〉
    Keywords: Antioxidants/*metabolism ; Carotenoids/*metabolism ; Chemical Phenomena ; Chemistry ; Free Radicals ; Humans ; Linoleic Acids/metabolism ; *Lipid Metabolism ; Oxidation-Reduction ; Oxygen/metabolism ; Partial Pressure ; Peroxides/metabolism ; Tetrahydronaphthalenes/metabolism ; beta Carotene
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  • 13
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    Bromine residue at hydrophilic region influences biological activity of aplysiatoxin, a tumor promoter (1983)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1983-12-16
    Description: Aplysiatoxin and debromoaplysiatoxin, which are isolated from the seaweed, Lyngbya gracilis, differ in their chemical structure only by the presence or absence of a bromine residue in the hydrophilic region. The function and the structure-activity relation of the hydrophilic region are not known. Aplysiatoxin increased malignant transformation, stimulated DNA synthesis, and inhibited the binding of phorbol-12,13-dibutyrate and epidermal growth factor to cell receptors. Debromoaplysiatoxin inhibited the binding of these two substances as strongly as aplysiatoxin but did not increase malignant transformation or stimulate DNA synthesis. These results indicate that a slight change in the chemical structure of the hydrophilic region of aplysiatoxin affects its abilities to increase cell transformation and stimulate DNA synthesis and that the abilities of the tumor promoters to inhibit the binding of phorbol-12,13-dibutyrate and epidermal growth factor are dissociable from their abilities to increase cell transformation and stimulate DNA synthesis under some circumstances.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Shimomura, K -- Mullinix, M G -- Kakunaga, T -- Fujiki, H -- Sugimura, T -- New York, N.Y. -- Science. 1983 Dec 16;222(4629):1242-4.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/6316505" target="_blank"〉PubMed〈/a〉
    Keywords: Animals ; *Caenorhabditis elegans Proteins ; Carcinogens/*pharmacology ; Carrier Proteins ; Cell Line ; Cell Transformation, Neoplastic/*drug effects ; Chemical Phenomena ; Chemistry ; DNA/biosynthesis ; Epidermal Growth Factor/metabolism ; Lactones/analysis/*pharmacology ; *Lyngbya Toxins ; Mice ; Phorbol 12,13-Dibutyrate ; Phorbol Esters/metabolism ; *Protein Kinase C ; Receptor, Epidermal Growth Factor ; Receptors, Cell Surface/metabolism ; *Receptors, Drug ; Structure-Activity Relationship
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  • 14
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    Phenylalanine transfer RNA: molecular dynamics simulation (1984)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1984-03-16
    Description: Yeast phenylalanine transfer RNA was subjected to a 12-picosecond molecular dynamics simulation. The principal features of the x-ray crystallographic analysis are reproduced, and the amplitudes of atomic displacements appear to be determined by the degree of exposure of the atoms. An analysis of the hydrogen bonds shows a correlation between the average length of a bond and the fluctuation in that length and reveals a rocking motion of bases in Watson-Crick guanine X cytosine base pairs. The in-plane motions of the bases are generally of larger amplitude than the out-of-plane motions, and there are correlations in the motions of adjacent bases.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Harvey, S C -- Prabhakaran, M -- Mao, B -- McCammon, J A -- New York, N.Y. -- Science. 1984 Mar 16;223(4641):1189-91.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/6560785" target="_blank"〉PubMed〈/a〉
    Keywords: Chemical Phenomena ; Chemistry ; Computers ; Cytosine ; Guanine ; Hydrogen Bonding ; Nucleic Acid Conformation ; *RNA, Fungal ; *RNA, Transfer, Amino Acyl ; Yeasts/analysis
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  • 15
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    Reaction of the antitumor antibiotic CC-1065 with DNA: structure of a DNA adduct with DNA sequence specificity (1984)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1984-11-16
    Description: Sequence-dependent variations in DNA revealed by x-ray crystallographic studies have suggested that certain DNA-reactive drugs may react preferentially with defined sequences in DNA. Drugs that wind around the helix and reside within one of the grooves of DNA have perhaps the greatest chance of recognizing sequence-dependent features of DNA. The antitumor antibiotic CC-1065 covalently binds through N-3 of adenine and resides within the minor groove of DNA. This drug overlaps with five base pairs for which a high sequence specificity exists.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Hurley, L H -- Reynolds, V L -- Swenson, D H -- Petzold, G L -- Scahill, T A -- New York, N.Y. -- Science. 1984 Nov 16;226(4676):843-4.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/6494915" target="_blank"〉PubMed〈/a〉
    Keywords: Antibiotics, Antineoplastic/*metabolism ; *Base Sequence ; Binding Sites ; Chemical Phenomena ; Chemistry ; DNA/*metabolism ; *Indoles ; Leucomycins/*metabolism ; Molecular Conformation ; X-Ray Diffraction
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  • 16
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    Allylamine derivatives: new class of synthetic antifungal agents inhibiting fungal squalene epoxidase (1984)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1984-06-15
    Description: A new class of synthetic antifungal agents, the allylamines , has been developed by modification of naftifine , a topical antimycotic. SF 86-327, the most effective of these compounds so far, is highly active in vitro against a wide range of fungi and exceeds clinical standards in the oral and topical treatment of guinea pig dermatophytoses. SF 86-327 is a powerful specific inhibitor of fungal squalene epoxidase, a key enzyme in sterol biosynthesis.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Petranyi, G -- Ryder, N S -- Stutz, A -- New York, N.Y. -- Science. 1984 Jun 15;224(4654):1239-41.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/6547247" target="_blank"〉PubMed〈/a〉
    Keywords: Allylamine/analogs & derivatives/*chemical synthesis/pharmacology ; Amines/*chemical synthesis ; Animals ; Antifungal Agents/*chemical synthesis/pharmacology ; Chemical Phenomena ; Chemistry ; Dermatomycoses/drug therapy ; Fungi/*drug effects/enzymology ; Guinea Pigs ; Naphthalenes/chemical synthesis/pharmacology ; Oxygenases/*antagonists & inhibitors ; Squalene Monooxygenase
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    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
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    Disulfide bond engineered into T4 lysozyme: stabilization of the protein toward thermal inactivation (1984)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1984-11-02
    Description: By recombinant DNA techniques, a disulfide bond was introduced at a specific site in T4 lysozyme, a disulfide-free enzyme. This derivative retained full enzymatic activity and was more stable toward thermal inactivation than the wild-type protein. The derivative, T4 lysozyme (Ile3----Cys), was prepared by substituting a Cys codon for an Ile codon at position 3 in the cloned lysozyme gene by means of oligonucleotide-dependent, site-directed mutagenesis. The new gene was expressed in Escherichia coli under control of the (trp-lac) hybrid tac promoter, and the protein was purified. Mild oxidation generated a disulfide bond between the new Cys3 and Cys97, one of the two unpaired cysteines of the native molecule. Oxidized T4 lysozyme (Ile3----Cys) exhibited specific activity identical to that of the wild-type enzyme when measured at 20 degrees C in a cell-clearing assay. The cross-linked protein was more stable than the wild type during incubation at elevated temperatures as determined by recovered enzymatic activity at 20 degrees C.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Perry, L J -- Wetzel, R -- New York, N.Y. -- Science. 1984 Nov 2;226(4674):555-7.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/6387910" target="_blank"〉PubMed〈/a〉
    Keywords: Chemical Phenomena ; Chemistry ; DNA, Recombinant/metabolism ; Escherichia coli/enzymology ; *Genetic Engineering ; Kinetics ; Muramidase/*genetics/metabolism ; Protein Denaturation
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  • 18
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    DNA-binding proteins (1983)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1983-09-09
    Description: The structures of three proteins that regulate gene expression have been determined recently and suggest how these proteins may bind to their specific recognition sites on the DNA. One protein (Cro) is a repressor of gene expression, the second (CAP) usually stimulates gene expression, and the third (lambda repressor) can act as either a repressor or an activator. The three proteins contain a substructure consisting of two consecutive alpha helices that is virtually identical in each case. Structural and amino acid sequence comparisons suggest that this bihelical fold occurs in a number of proteins that regulate gene expression, and is an intrinsic part of the DNA-protein recognition event. The modes of repression and activation by Cro and lambda repressor are understood reasonably well, but the mode of action of CAP is still unclear.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Takeda, Y -- Ohlendorf, D H -- Anderson, W F -- Matthews, B W -- GM20066/GM/NIGMS NIH HHS/ -- GM28138/GM/NIGMS NIH HHS/ -- GM30894/GM/NIGMS NIH HHS/ -- New York, N.Y. -- Science. 1983 Sep 9;221(4615):1020-6.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/6308768" target="_blank"〉PubMed〈/a〉
    Keywords: Amino Acid Sequence ; Chemical Phenomena ; Chemistry ; *DNA Helicases ; DNA-Binding Proteins ; Escherichia coli/genetics ; Gene Expression Regulation ; Models, Chemical ; Protein Conformation
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  • 19
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    A nitrogen pressure of 50 atmospheres does not prevent evolution of hydrogen by nitrogenase (1984)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1984-06-08
    Description: The effect of a partial pressure of nitrogen of 50 atmospheres (5065 kilopascals ) on the hydrogen evolution reaction of nitrogenase has been investigated. Evolution of hydrogen was not blocked completely by 50 atmospheres of nitrogen in any of four experiments; rather, 27.3 +/- 2.4 percent of the total electron flux through nitrogenase was directed toward production of hydrogen. The ratio of hydrogen evolved to nitrogen fixed was close to 1:1, which implies that hydrogen evolution is obligatory in the fixation of molecular nitrogen by nitrogenase.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Simpson, F B -- Burris, R H -- AI-00848/AI/NIAID NIH HHS/ -- New York, N.Y. -- Science. 1984 Jun 8;224(4653):1095-7.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/6585956" target="_blank"〉PubMed〈/a〉
    Keywords: Chemical Phenomena ; Chemistry ; *Hydrogen ; *Nitrogen ; Nitrogen Fixation ; *Nitrogenase ; Partial Pressure
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  • 20
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    Nonvolatile mutagens in drinking water: production by chlorination and destruction by sulfite (1980)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1980-01-04
    Description: In concentrates of water produced in a laboratory simulation of a drinking water treatment process, direct-acting, nonvolatile mutagens were readily detected by means of the Ames Salmonella test. The mutagens were shown to be produced by the chlorination process. Treatment of the water with chloramine resulted in less mutagenic activity than treatment with free chlorine. Dechlorination of drinking water with sulfite sharply reduced the mutagenic activity. Treatment with sulfur dioxide is proposed as an effective, inexpensive method of reducing the direct-acting mutagenic activity of drinking water and of aqueous industrial effluents.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Cheh, A M -- Skochdopole, J -- Koski, P -- Cole, L -- New York, N.Y. -- Science. 1980 Jan 4;207(4426):90-2.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/6985746" target="_blank"〉PubMed〈/a〉
    Keywords: Chemical Phenomena ; Chemistry ; Chloramines ; Chlorine ; Mutagens/*analysis ; Salmonella typhimurium/genetics ; Sulfites ; Water Pollutants/*analysis ; Water Pollutants, Chemical/*analysis ; Water Supply/*analysis
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  • 21
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    Automated synthesis of gene fragments (1981)
    American Association for the Advancement of Science (AAAS)
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    Publication Date: 1981-10-16
    Description: The DNA/RNA Synthesizer provides a complete and automated procedure for the synthesis of DNA sequences. Each base unit is added in a 30-minute cycle, permitting a tetradecamer to be constructed in 6 1/2 hours. The complete procedure is described, including a practical procedure for isolation and purification of the desired DNA sequence.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Alvarado-Urbina, G -- Sathe, G M -- Liu, W C -- Gillen, M F -- Duck, P D -- Bender, R -- Ogilvie, K K -- New York, N.Y. -- Science. 1981 Oct 16;214(4518):270-4.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/6169150" target="_blank"〉PubMed〈/a〉
    Keywords: Automation ; Chemical Phenomena ; Chemistry ; DNA/*chemical synthesis ; *Genes, Synthetic ; RNA/*chemical synthesis ; Solubility
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  • 22
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    Chitin: New facets of research (1981)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1981-05-15
    Description: Research on chitin as a marine resource is pointing to novel applications for this cellulose-like biopolymer. Discovery of nondegrading solvent systems has permitted the spinning of filaments, for example, for use as surgical sutures. New methods for preparing the bioactive alkyl glycoside of N-acetyl-D-glucosamine (the monomer unit of chitin) and a microcrystalline chitin has encouraged their use as promoters for growth of bifidobacteria and as an aid in digestion of high-lactose cheese whey by domestic animals. Chitin-protein complexes of several crustacean species show great variability in ratios of chitin to covalently bound protein and in residual protein in the "purified" chitins.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Austin, P R -- Brine, C J -- Castle, J E -- Zikakis, J P -- New York, N.Y. -- Science. 1981 May 15;212(4496):749-53.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/7221561" target="_blank"〉PubMed〈/a〉
    Keywords: Animal Feed ; Animals ; Cheese ; Chemical Phenomena ; Chemistry ; Chickens ; *Chitin ; Crystallography ; Lactose/metabolism ; Proteins/analysis ; Sutures ; *Technology
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  • 23
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    DNA sequencing and gene structure (1981)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1981-12-18
    Description: 〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Gilbert, W -- New York, N.Y. -- Science. 1981 Dec 18;214(4527):1305-12.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/7313687" target="_blank"〉PubMed〈/a〉
    Keywords: Base Sequence ; Chemical Phenomena ; Chemistry ; DNA/*genetics ; Eukaryotic Cells/physiology ; *Genes ; Hydrazines ; Lac Operon ; Methylation ; Prokaryotic Cells/physiology ; Sulfuric Acid Esters
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  • 24
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    Boradeption: a new procedure for transferring water-insoluble agents across cell membranes (1982)
    American Association for the Advancement of Science (AAAS)
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    Publication Date: 1982-07-09
    Description: A new process has been developed which is called "Boradeption" to signify boronic acid--dependent phase transfer of water-insoluble agents. Highly fluorescent boronic acid dervatives, FluoroBoras, are solubilized with a physiologically compatible carrier buffer containing a receptor group for boronate adduct formation. The system can be used to stain living cells. In another variation of the Boradeption concept, an insoluble reporter molecule containing a boronate receptor is solubilized with a carrier buffer containing a boronic acid functional group. The boronate-receptor complexes, which are in dynamic equilibrium, can be designed as vital stains and reagents for a variety of biological and medical applications.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Gallop, P M -- Paz, M A -- Henson, E -- AG-00376-07/AG/NIA NIH HHS/ -- HL-20764-04A1/HL/NHLBI NIH HHS/ -- New York, N.Y. -- Science. 1982 Jul 9;217(4555):166-9.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/6178158" target="_blank"〉PubMed〈/a〉
    Keywords: Animals ; *Biological Transport ; *Boron Compounds/therapeutic use ; *Boronic Acids/therapeutic use ; *Cell Membrane Permeability ; Cells, Cultured ; Chemical Phenomena ; Chemistry ; Chromogenic Compounds/metabolism ; Cricetinae ; Fibroblasts ; Fluorescent Dyes/metabolism ; Humans ; Rats ; Staining and Labeling
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    Reversible chemical modification of the scrapie agent (1981)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1981-12-11
    Description: The scrapie agent causes a degenerative nervous system disease in sheep and goats. Studies with extensively purified preparations demonstrated that the agent contains a protein that is required for infectivity. Chemical modification of the scrapie agent by diethyl pyrocarbonate reduced the titer 1000-fold. Exposure of the inactivated agent to hydroxylamine, a strong nucleophile, resulted in complete restoration of infectivity. Presumably, nucleophilic residues within a scrapie agent protein undergo carbethoxylation on reaction with diethyl pyrocarbonate, and subsequent addition of hydroxylamine displaces these carbethoxy groups.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉McKinley, M P -- Masiarz, F R -- Prusiner, S B -- NS14069/NS/NINDS NIH HHS/ -- New York, N.Y. -- Science. 1981 Dec 11;214(4526):1259-61.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/6795721" target="_blank"〉PubMed〈/a〉
    Keywords: Animals ; Biological Assay ; Brain/microbiology ; Chemical Phenomena ; Chemistry ; Cricetinae ; Diethyl Pyrocarbonate/pharmacology ; Histidine/pharmacology ; *Prions ; Ribonucleases/pharmacology ; Serum Albumin, Bovine/pharmacology ; Viral Proteins/*isolation & purification/pharmacology
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    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
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  • 26
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    Nonenzymatic browning in vivo: possible process for aging of long-lived proteins (1981)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1981-01-30
    Description: The incubation of lens proteins with reducing sugars leads to the formation of fluorescent yellow pigments and cross-like similar to those reported in aging and cataractous human lenses. Called nonenzymatic browning or the Maillard reaction, this aging process also occurs in stored foods. Reducing sugars condense with the free amino group of proteins, then rearrange and dehydrate to form unsaturated pigments and cross-linked products. Although most proteins in living systems turn over with sufficient rapidity to avoid nonenzymatic browning, some, such as lens crystallins and skin collagen, are exceptionally long-lived and may be vulnerable.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Monnier, V M -- Cerami, A -- AM 19655/AM/NIADDK NIH HHS/ -- New York, N.Y. -- Science. 1981 Jan 30;211(4481):491-3.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/6779377" target="_blank"〉PubMed〈/a〉
    Keywords: *Aging ; Animals ; Cattle ; Chemical Phenomena ; Chemistry ; *Crystallins ; Diabetes Mellitus/physiopathology ; Glucose ; Glucosephosphates ; In Vitro Techniques ; Lysine ; *Proteins ; Spectrophotometry, Ultraviolet
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    The National Science Foundation looks to the future (1981)
    American Association for the Advancement of Science (AAAS)
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    Publication Date: 1981-03-13
    Description: Great advances have been made in fundamental scientific research in recent years. The new knowledge gathered, in addition to deepening our understanding of the physical universe, contributes a range of abilities and opportunities to society that would not otherwise be available. Much research that may be called applied because it addresses needs of society is quite fundamental in character, and support of such research at the National Science Foundation is to be handled in tandem by the research directorates. Other areas that require a refocusing of support are engineering science and education, at all levels, in science and engineering. Increasing our strength in these areas is essential to achieve our national economic, social, and political goals. Steps are being taken by the National Science Foundation to make its structure better able to deal with engineering and applied research and to provide greater mutual reinforcement between applied and basic research.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Slaughter, J B -- New York, N.Y. -- Science. 1981 Mar 13;211(4487):1131-6.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/7466384" target="_blank"〉PubMed〈/a〉
    Keywords: Cell Biology ; Chemical Phenomena ; Chemistry ; *Forecasting ; Geological Phenomena ; Geology ; *Government Agencies ; Molecular Biology ; Neurochemistry ; Physical Phenomena ; Physics ; Research Support as Topic ; United States
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  • 28
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    New chemistry of an old molecule: cis-[Pt(NH3)2Cl2] (1982)
    American Association for the Advancement of Science (AAAS)
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    Publication Date: 1982-12-10
    Description: The discovery that cis-diamminedichloroplatinum(II) (cis-DDP) has clinically useful antitumor properties and can form platinum blues spawned an extensive investigation of its chemistry in water. Several new molecules have been synthesized, some rather old ones have been characterized for the first time, and clues have begun to emerge about the chemical interaction of cis-DDP with its likely biological target, DNA.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Lippard, S J -- New York, N.Y. -- Science. 1982 Dec 10;218(4577):1075-82.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/6890712" target="_blank"〉PubMed〈/a〉
    Keywords: Chemical Phenomena ; Chemistry ; *Cisplatin ; *Dna ; Hydrolysis ; Pigments, Biological
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  • 29
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    The chemistry of vision (1982)
    American Association for the Advancement of Science (AAAS)
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    Publication Date: 1982-12-03
    Description: The visual response is initiated by light reception and transduction into chemical and electrical energy in the outer-segment membranes of rod and cone cells. Recent research on the molecular events controlled by light has clarified the roles of some of the rod outer-segment biomolecules. These developments and the current unresolved questions are described.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉O'Brien, D F -- New York, N.Y. -- Science. 1982 Dec 3;218(4576):961-6.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/6291153" target="_blank"〉PubMed〈/a〉
    Keywords: Animals ; Blood Proteins/metabolism ; Calcium/metabolism ; Chemical Phenomena ; Chemistry ; Enzyme Activation ; Enzymes/metabolism ; GTP-Binding Proteins ; Light ; Membranes/metabolism ; Models, Biological ; Phosphoric Diester Hydrolases/biosynthesis ; Photoreceptor Cells/*metabolism ; Receptors, Cell Surface/metabolism ; Rhodopsin/metabolism ; Rod Cell Outer Segment/*metabolism ; Vision, Ocular/*physiology
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  • 30
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    Antiviral agents (1983)
    American Association for the Advancement of Science (AAAS)
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    Publication Date: 1983-06-10
    Description: 〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Krenitsky, T A -- Beauchamp, L -- New York, N.Y. -- Science. 1983 Jun 10;220(4602):1106.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/6857236" target="_blank"〉PubMed〈/a〉
    Keywords: Acyclovir/metabolism ; *Antiviral Agents/metabolism ; Chemical Phenomena ; Chemistry ; Humans ; Vidarabine/metabolism
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  • 31
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    Metastable species of hemoglobin: room temperature transients and cryogenically trapped intermediates (1983)
    American Association for the Advancement of Science (AAAS)
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    Publication Date: 1983-05-06
    Description: Resonance Raman spectra of photolyzed carbonmonoxyhemoglobin obtained with 10-nanosecond pulses are compared with the spectra of photolyzed carbonmonoxyhemoglobin stabilized at 80 K. In comparing the deoxy with the photodissociated species, the changes in the Raman spectra are the same for these two experimental regimes. These results show that at ambient and cryogenic temperatures the heme pocket in liganded hemoglobin is significantly different from that of deoxyhemoglobin. It is concluded that measurements of the properties of intermediate species from photodissociated hemoglobin stabilized at low temperatures can be used to probe the short-lived metastable forms of hemoglobin present after photodissociation under biologically relevant solution conditions.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Ondrias, M R -- Friedman, J M -- Rousseau, D L -- New York, N.Y. -- Science. 1983 May 6;220(4597):615-7.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/6836305" target="_blank"〉PubMed〈/a〉
    Keywords: Carboxyhemoglobin ; Chemical Phenomena ; Chemistry ; Freezing ; *Hemoglobins ; Humans ; Ligands ; Spectrum Analysis, Raman ; Temperature
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  • 32
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    Irreversible ligands with high selectivity toward delta and mu opiate receptors (1983)
    American Association for the Advancement of Science (AAAS)
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    Publication Date: 1983-04-15
    Description: Alkylating agents that display strong selectivity for opiate receptor types delta or mu were prepared by appropriate modification of the structures of the strong analgesics fentanyl, etonitazene, and endoethenotetrahydrooripavine. The availability of these substances should facilitate studies of the structural basis of receptor specificity and of the physiologic roles of these receptors.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Rice, K C -- Jacobson, A E -- Burke, T R Jr -- Bajwa, B S -- Streaty, R A -- Klee, W A -- New York, N.Y. -- Science. 1983 Apr 15;220(4594):314-6.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/6132444" target="_blank"〉PubMed〈/a〉
    Keywords: Alkylation ; Animals ; Benzimidazoles/analogs & derivatives/metabolism ; Brain/physiology ; Cells, Cultured ; Chemical Phenomena ; Chemistry ; Enkephalin, Methionine/analogs & derivatives/metabolism ; Fentanyl/analogs & derivatives/metabolism ; *Isothiocyanates ; Ligands ; Rats ; Receptors, Opioid/*metabolism/physiology ; Thebaine/analogs & derivatives/pharmacology
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  • 33
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    Trace chemistries of fire: a source of chlorinated dioxins (1980)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1980-10-01
    Description: 〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Bumb, R R -- Crummett, W B -- Cutie, S S -- Gledhill, J R -- Hummel, R H -- Kagel, R O -- Lamparski, L L -- Luoma, E V -- Miller, D L -- Nestrick, T J -- Shadoff, L A -- Stehl, R H -- Woods, J S -- New York, N.Y. -- Science. 1980 Oct;210(4468):385-90.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/6159682" target="_blank"〉PubMed〈/a〉
    Keywords: Air Pollutants/analysis ; Chemical Phenomena ; Chemistry ; Chromatography, High Pressure Liquid ; *Dioxins/analysis ; *Fires ; Power Plants ; Smoke/analysis ; Soil Pollutants/analysis ; Tetrachlorodibenzodioxin/analysis ; Vehicle Emissions/analysis ; Water Pollutants, Chemical/analysis
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
    Published by American Association for the Advancement of Science (AAAS)
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  • 34
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    Synthetic competitive antagonists of corticotropin-releasing factor: effect on ACTH secretion in the rat (1984)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1984-05-25
    Description: Polypeptide analogs of the known members of the corticotropin-releasing factor (CRF) family were synthesized and tested in vitro and in vivo for enhanced potency or competitive antagonism. Predictive methods and physicochemical measurements had suggested an internal secondary alpha-helical conformation spanning about 25 residues for at least three members of the CRF family. Maximization of alpha-helix-forming potential by amino acid substitutions from the native known sequences (rat/human and ovine CRF, sauvagine, and carp and sucker urotensin 1) led to the synthesis of an analog that was found to be more than twice as potent as either of the parent peptides in vitro. In contrast, certain amino-terminally shortened fragments, such as alpha-helical CRF or ovine CRF residues 8 to 41, 9 to 41, and 10 to 41, were found to be competitive inhibitors in vitro. Selected antagonists were examined and also found to be active in vivo.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Rivier, J -- Rivier, C -- Vale, W -- AA03504/AA/NIAAA NIH HHS/ -- AM20917/AM/NIADDK NIH HHS/ -- AM26741/AM/NIADDK NIH HHS/ -- etc. -- New York, N.Y. -- Science. 1984 May 25;224(4651):889-91.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/6326264" target="_blank"〉PubMed〈/a〉
    Keywords: Adrenocorticotropic Hormone/secretion ; Animals ; Binding, Competitive ; Chemical Phenomena ; Chemistry ; Corticotropin-Releasing Hormone/*antagonists & inhibitors ; Rats
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
    Published by American Association for the Advancement of Science (AAAS)
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  • 35
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    The High Resolution Spectrograph for the Space Telescope (1982)
    In:  CASI
    Details
    Publication Date: 2009-11-16
    Description: The High Resoltuion Spectrograph (HRS) in conjunction with the Space Telescope (ST), extends ultraviolet astronomical spectroscopy to higher spectra, spatial, and time resolutions than previously achieved, as well as to fainter and more distant celestial objects. Other significant advances inherent in the instrument are high photometric accuracy and efficient operation via exposure meter control and real time rejection of bad data. These capabilities are provided to accomplish the scientific programs of the HRS investigation definition team, which concern the interstellar medium, stellar winds, and evolutionary aspects of stellar atmosphere studies; the determination of chemical abundances relevant to stellar evolution; the investigation of quasars and Seyfert galaxy nuclei; and the analysis of the atmospheres of solar system objects, including comets.
    Keywords: ASTRONOMY
    Type: Space Telescope Science Inst. The Space Telescope Obs.; p 76-105
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    The PDS-VAX intelligent plate scanning system of Trieste Astronomical Observatory (1984)
    In:  CASI
    Details
    Publication Date: 2006-02-14
    Description: An intelligent subsystem for interfacing a PDS1010A digital microdensitometer to a DEC DR11W DMA 16 bit UNIBUS port in DEC VAX VMS environment was tested. The subsystem employs two MOTOROLA M68000 microprocessors with 128 KB data memory. The PDS primitives and the user defined high level scanning functions and preprocessing modules are loaded from the host computer into two 8 KB RAM memories in the microprocessors using a dedicated PDS control language. The subsystem is planned to employ a nonstandard photomultiplier electronics. Two design schemes were tested: (1) based on three amplifiers of gain 10 cascaded and multiplexed to a 12 bit AD converter, and (2) based on a single amplifier of gain 100 and two 14 bit AD converters.
    Keywords: ASTRONOMY
    Type: NASA. Goddard Space Flight Center Astron. Microdensitometry Conf.; p 175-187
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  • 37
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    Reflections on the Space Telescope (1982)
    In:  CASI
    Details
    Publication Date: 2006-02-14
    Description: The significance of the Space Telescope for the advancement of astronomy and astrophysics is described. The current state of knowledge in astronomy and cosmology is summarized and unanswered questions in those fields discussed. The rapid evolution of modern astronomy and the need for systematic observations are stressed.
    Keywords: ASTRONOMY
    Type: Space Telescope Science Inst. The Space Telescope Obs.; p 121-134
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  • 38
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    Astrometric observations with the Space Telescope (1982)
    In:  CASI
    Details
    Publication Date: 2006-02-14
    Description: Astrometry with the Space Telescope (ST) is performed using one of the fine guidance sensors (FGS). The FGS, which is based on a pair of Koester's prism interferometers, one for each axis, is capable of measuring the position of one object relative to another with an accuracy of 0.002 arcseconds. Astrometric Data Reduction Software (ADRS) available to the astrometric user of ST is described. The kinds of problems the space telescope astrometry team plans to investigate using ST are discussed.
    Keywords: ASTRONOMY
    Type: Space Telescope Science Inst. The Space Telescope Obs.; p 114-120
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  • 39
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    The wide field/planetary camera (1982)
    In:  CASI
    Details
    Publication Date: 2006-02-14
    Description: A wide site of potential astronomical and solar system scientific studies using the wide field planetary camera on space telescope are described. The expected performance of the camera as it approaches final assembly and testing is also detailed.
    Keywords: ASTRONOMY
    Type: Space Telescope Science Inst. The Space Telescope Obs.; p 28-39
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  • 40
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    European astronomy and the Space Telescope: The Space Telescope European Coordinating Facility (1982)
    In:  CASI
    Details
    Publication Date: 2006-02-14
    Description: The role of the European Coordinating Facility is described. European participation in the Space Telescope Science Institute and the relation of Space Telescope to ground-based astronomy in Europe are discussed.
    Keywords: ASTRONOMY
    Type: Space Telescope Science Inst. The Space Telescope Obs.; p 16-19
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  • 41
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    Spectroscopy in X-ray astronomy (1981)
    In:  CASI
    Details
    Publication Date: 2006-06-04
    Description: Detailed features in cosmic X-ray sources and their associated temporal variation over a wide energy range were studied. Excess emission and absorption at approximately 6 to 7 kiloelectron volts in the spectra of supernova remnants, binary X-ray sources, and clusters of galaxies were observed. A gas scintillation proportional counter (GSPC) will be used as the detector system. In the gas scintillator the principal limitation is due to the statistics of the initial ionization process only.
    Keywords: ASTRONOMY
    Type: NASA. Marshall Space Flight Center Spacelab Mission 1 Expt. Descriptions; 3 p
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  • 42
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    Far ultraviolet astronomy using the FAUST telescope (1981)
    In:  CASI
    Details
    Publication Date: 2006-06-04
    Description: The Far Ultraviolet Space Telescope (FAUST) a compact, wide field-of-view, far ultraviolet instrument designed for astronomical observations of extended and point sources is discussed. The design and application of the instrument are described. The prime objective is to observe faint astronomical sources with sensitivities higher than previously available. Scientific programs will include: (1) a search for ultraviolet stars which are predicted to exist at the stage of evolution prior to the final death of a star; (2) observations of galaxies and quasars; and (3) joint programs with other Spacelab 1 experiments. The secondary objective is to verify the suitability of the Spacelab as a platform for far ultraviolet astronomy: data will be provided on the ultraviolet background levels due to astronomical, terrestrial, and spacecraft generated sources; the levels of contaminants which affect ultraviolet instruments; and the capability of the Orbiter for stable pointing at celestial sources for useful periods of time.
    Keywords: ASTRONOMY
    Type: NASA. Marshall Space Flight Center Spacelab Mission 1 Expt. Descriptions; 3 p
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  • 43
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    The High Speed Photometer for the Space Telescope (1982)
    In:  CASI
    Details
    Publication Date: 2006-02-14
    Description: An overview of the high speed photometer (HSP), its optics and detectors, its electronics, its mechanical structure, and some observational considerations are presented. The capabilities and limitations of the HSP are outlined.
    Keywords: ASTRONOMY
    Type: Space Telescope Science Inst. The Space Telescope Obs.; p 106-113
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  • 44
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    The Faint Object Camera (1982)
    In:  CASI
    Details
    Publication Date: 2006-02-14
    Description: The Faint Object Camera fully exploits the spatial resolution capability of the Space Telescope on the very faintest detectable objects over a broad wavelength range. A full complement of filters, objective prisms and polarizers, a choice of coronograhic masks, and a variety of scan formats extend the scientific versatility of the direct imaging mode. In addition, the Faint Object Camera provides the unique facility of long-slit spectroscopy to Space Telescope observers.
    Keywords: ASTRONOMY
    Type: Space Telescope Science Inst. The Space Telescope Obs.; p 40-54
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  • 45
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    Astronomical capabilities of the Faint Object Spectrograph on Space Telescope (1982)
    In:  CASI
    Details
    Publication Date: 2006-02-14
    Description: Examples of scientific observing programs planned with the Faint Object Spectrograph on Space Telescope are presented. An overview of the spectrograph design and operation is presented. The expected astronomical performance of the instrument is described in some detail.
    Keywords: ASTRONOMY
    Type: Space Telescope Science Inst. The Space Telescope Obs.; p 55-75
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  • 46
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    The Space Telescope Observatory (1982)
    In:  CASI
    Details
    Publication Date: 2006-02-14
    Description: The history of the observatory is briefly described, as is the overall system design. The principal design features that are important to the scientific user are described. The present status of preparation for launch in the spring of 1985 is summarized.
    Keywords: ASTRONOMY
    Type: Space Telescope Science Inst. The Space Telescope Obs.; p 20-27
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  • 47
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    STEP flight experiments Large Deployable Reflector (LDR) telescope (1984)
    In:  CASI
    Details
    Publication Date: 2006-04-03
    Description: Flight testing plans for a large deployable infrared reflector telescope to be tested on a space platform are discussed. Subsystem parts, subassemblies, and whole assemblies are discussed. Assurance of operational deployability, rigidization, alignment, and serviceability will be sought.
    Keywords: ASTRONOMY
    Type: NASA. Langley Research Center STEP Expt. Requirements; p 257-278
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  • 48
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    Science operations with Space Telescope (1982)
    In:  CASI
    Details
    Publication Date: 2006-02-14
    Description: The operation, instrumentation, and expected contributions of the Space Telescope are discussed. Space Telescope capabilities are described. The organization and nature of the Space Telescope Science Institute are outlined, including the allocation of observing time and the data rights and data access policies of the institute.
    Keywords: ASTRONOMY
    Type: The Space Telescope Obs.; p 1-15
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  • 49
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    Infrared mapping of galaxian centers: Star forming regions with kiloparsec scale sizes (1984)
    In:  Other Sources
    Details
    Publication Date: 2011-08-19
    Description: A 1 to 20 micron mapping of the centers of galaxies encompassing the regions that extend out to several kiloparsecs from the nuclei is reviewed. Power emerging at or = 5 microns is a direct measure of the number of young stars present. This conclusion is strongly supported by the large-scale association of the infrared-emitting regions with visual continuum and line emission indicative of young stars, and by the similarity of the energy distributions to those of Galactic HII region/molecular cloud complexes. Much of the young-star activity is completely hidden from view. At shorter wavelengths, a variety of processes, including bremsstrahlung, are evident.
    Keywords: ASTRONOMY
    Type: Royal Observatory Star Formation Workshop; p 183-198
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  • 50
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    The Gamma-Ray Observatory mission objectives and its significance for gamma-ray astronomy (1984)
    In:  Other Sources
    Details
    Publication Date: 2011-08-18
    Description: The Gamma Ray Observatory (GRO) is an approved NASA mission, programmed for launch in 1988. Its complement of four detectors has established goals: (1) to study the nature of compact gamma-ray sources such as neutron stars and black holes, or objects whose nature is yet to be understood; (2) to search for evidence of nucleosynthesis especially in the regions of supernovae; (3) to study structural features and dynamical properties of the Galaxy; (4) to explore other galaxies, especially the extraordinary types such as radio, Seyferts, and quasars; and (5) to study cosmological effects by examining the diffuse radiation in detail. This paper discusses the design, objectives, and expected scientific results of each of the GRO instruments in view of the GRO mission goals.
    Keywords: ASTRONOMY
    Type: Advances in Space Research (ISSN 0273-1177); 3; 10-12
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  • 51
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    The S201 far-ultraviolet imaging survey. II - A field in Cygnus (1984)
    In:  Other Sources
    Details
    Publication Date: 2011-08-18
    Description: Far-ultraviolet imagery of a region in Cygnus, a 20 deg diameter field centered near (1950) R. A. 21 h 31.2 m decl. +37 deg 25 arcmin, was obtained by the S201 far-ultraviolet camera during the Apollo 16 mission. In a 10 minute exposure covering the 1250-1600 A wavelength range (effective wavelength 1400 A), 730 star images can be detected, corresponding to a limiting ultraviolet magnitude of about m (1400) = 10. Assuming nominal interstellar extinction values in this region near the galactic plane, this result corresponds to the detection of A0 V stars to a distance of 300 pc and of B0 V stars to 1500 pc. Uncertainties in spectral classification and interstellar extinction for individual objects are probably more significant than calibration or measurement errors. Most of the objects detected are identified with stars in the Smithsonian Astrophysical Observatory Star Catalog (1966), or the Catalog of Stellar Identifications (1979) or both, but 87 objects remain unidentified (or are identified with late-type stars).
    Keywords: ASTRONOMY
    Type: Astrophysical Journal Supplement Series (ISSN 0067-0049); 54; 271-290
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  • 52
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    Determining asteroid masses from perturbations on Mars (1984)
    In:  Other Sources
    Details
    Publication Date: 2011-08-18
    Description: The orbit of Mars is perturbed more than 5 m, a value compatible with the accuracy of the Viking Lander ranging data, by about three dozen asteroids. In addition to larger asteroids throughout the belt, significant perturbations of long period are generated by smaller objects near commensurabilities with Mars. The largest periodic terms induced by 1 Ceres and 2 Pallas have amplitudes of 0.8 and 0.2 km, respectively, both with 10-year periods. Due to a near commensurability, 4 Vesta causes a 5-km, 52-year term. While the Viking ranges will yield significant mass determinations for the largest three asteroids, and some of the smaller bodies should be detectable, it will be difficult to separate the smaller bodies with useful accuracies. Accurate discrimination must await range data from future missions to Mars or other bodies in the neighborhood of the asteroid belt. The Viking ranges can also yield improved masses for the outer planets (except Pluto), an application which is being exploited by groups analyzing these data. Uncertainties in the asteroid masses limit the ultimate accuracy of the Viking determinations of both the long time scale motion of the system of the inner four planets with respect to an inertial frame and the rate of change of the gravitational constant.
    Keywords: ASTRONOMY
    Type: Icarus (ISSN 0019-1035); 57; 1-13
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  • 53
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    A search for the 10-micron silicate feature in periodic Comet Grigg-Skjellerup (1984)
    In:  Other Sources
    Details
    Publication Date: 2011-08-18
    Description: A 10-micron spectrum of periodic Comet Grigg-Skjellerup was obtained on 22 June 1982 with the UCL array spectrometer at the United Kingdom Infrared Telescope, Mauna Kea. No emission feature is obvious in the spectrum. The observed spectrum can be fit equally well by a model of small hot absorbing grains or by a composite model with less than or equal to 30 percent (3sigma) warm, 'dirty' silicate grains. The latter model is consistent with the silicate abundance in Comet Kohoutek, which did display an emission feature at 10 microns.
    Keywords: ASTRONOMY
    Type: Astronomical Journal (ISSN 0004-6256); 89; 170
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  • 54
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    Broad band X-ray astronomical spectroscopy (1984)
    In:  Other Sources
    Details
    Publication Date: 2011-08-18
    Description: The Broad Band X-Ray Telescope (BBXRT) experiment has been designed for high sensitivity, moderate resolution spectrophotometry of cosmic sources in the range 0.5 to 12 keV. Principal elements are two co-aligned imaging telescopes with cooled Si(Li) detectors at each focus. The mirror design uses an approximate geometry of tightly nested, conical, foil reflectors that allow a large filling factor (high throughput) at small grazing angles (high energy response). Each detector consists of a cluster of five elements defined with grooves on a single crystal. This arrangement affords some spatial resolution as well as a means of substantial background reduction. Shuttle borne measurements will typically be of 2000 s duration for sources with a flux of 10 to the -12 erg/sq cm-s.
    Keywords: ASTRONOMY
    Type: IEEE Transactions on Nuclear Science (ISSN 0018-9499); NS-31; 786-790
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    Ultraviolet spectra of planetary nebulae. X - Physical conditions in the compact planetary nebula Sw St 1 (1984)
    In:  Other Sources
    Details
    Publication Date: 2011-08-18
    Description: Photoelectric visual and ultraviolet observations of the compact planetary nebula Sw St 1 are analyzed. The electron density, determined from the C III 1907/1909 A line ratio, is N(e) = (1.1 + or - 0.1) x 10 to the 5th/cu cm, consistent with the high emission measure and high critical frequency determined from observations of the thermal radio emission. The C/O abundance ratio in the nebula is found to be N(C)/N(O) = 0.72 + or - 0.1, i.e. the envelope is oxygen-rich, as suggested by the identification of the silicate feature in the 8-13 micron infrared spectrum. Difficulties remain in accurately determining the reddening constant to the nebula and its electron temperature.
    Keywords: ASTRONOMY
    Type: Royal Astronomical Society, Monthly Notices (ISSN 0035-8711); 206; 293-304
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  • 56
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    Detection of silicate emission features in the 8- to 13-micron spectra of main belt asteroids (1983)
    In:  Other Sources
    Details
    Publication Date: 2011-08-18
    Description: A presentation is given of 8.0-13.0 micron spectra (Delta lambda/lambda = 0.02-0.03) for six main belt asteroids, which range from 58 to 220 km in diameter and sample the five principal taxonomic classes (C, S, M, R and E). Narrow, well-defined silicate emission features are present on two of the asteroids, the C-type 19 Fortuna and the M-type 21 Lutetia. No comparable emission features are observed on the S-types 11 Parthenope and 14 Irene, the R-type 349 Dembowska or the E-type 64 Angelina.
    Keywords: ASTRONOMY
    Type: Icarus (ISSN 0019-1035); 56; 393-397
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  • 57
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    Radioastronomical observations of comets IRAS-Araki-Alcock (1983d) and Sugano-Saigusa-Fujikawa (1983e) (1984)
    In:  Other Sources
    Details
    Publication Date: 2011-08-19
    Description: Continuum and spectral-line radio observations of the comets IRAS-Araki-Alcock and Sugano-Saigusa-Fujikawa obtained at a number of observatories during May and June, 1983, are compiled in tables and briefly characterized. The species NH3, H2O, CO, and HCN are considered in detail; visible-range observations of CN are compared; and the implications of the results and the experience gained in performing and coordinating the observations for the detection of important species in other comets, especially Halley's Comet, are explored.
    Keywords: ASTRONOMY
    Type: Icarus (ISSN 0019-1035); 60; 215-220
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  • 58
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    A search at the millijansky level for milli-arcsecond cores in a complete sample of radio galaxies (1984)
    In:  Other Sources
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    Publication Date: 2011-08-19
    Description: A complete sample of 26 extended radio galaxies was observed at 2.29 GHz with the Mark III VLBI system. The fringe spacing was about 3 milli-arcsec, and the detection limit was about 2 millijanskys. Half of the galaxies were found to possess milli-arcsec radio cores. In all but three sources, the nuclear flux density was less than 0.04 of the total flux density. Galaxies with high optical luminosity (less than -21.2) were more likely than less luminous galaxies to contain a detectable milliparcsec radio core (69 percent vs. 20 percent). For objects with arcsec cores, 80 percent were found to have a milli-arcsec core, even though the milli-arcsec object did not always contribute the greater part of the arcsec flux density.
    Keywords: ASTRONOMY
    Type: Astrophysical Journal, Part 1 (ISSN 0004-637X); 284; 519-522
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  • 59
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    The evolution of the infrared emission from the Type II supernova 1980k in NGC 6946 - The dust formation model (1983)
    In:  Other Sources
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    Publication Date: 2011-08-18
    Description: The paper presents 1-4 micron photometry of supernova 1980 k in NGC 6946 obtained over a period of 1 year following the outburst. During the period between 1980 November 1 and December 19, the infrared emission probably originated from the extended atmosphere of the expanding star. The JHKL colors and a 1.3-2.6-micron spectrum observed during this period correspond to those of a blackbody with an average temperature of about 5000 K. Observations around 1981 May 31 showed that the supernova developed an infrared excess after 1980 December. This infrared excess persisted through 1981 October and is consistent with the appearance of thermal emission from about 700 to 900 K dust in addition to a hotter photosphere. The similarity of this behavior to that of the infrared evolution of some novae suggests that dust formation may be occurring in the supernova ejecta. The hypothesis, that the emission arises from preexisting grains in a circumstellar shell which are heated by the supernova outburst, is also consistent with the data.
    Keywords: ASTRONOMY
    Type: Astrophysical Journal, Part 1 (ISSN 0004-637X); 274; 168-174
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  • 60
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    Ultraviolet and optical studies of binaries with luminous cool primaries and hot companions. III - Reticon radial velocities (1983)
    In:  Other Sources
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    Publication Date: 2011-08-18
    Description: Radial velocities for 72 stars, most of them known or suspected binaries with F - K giant-supergiant primaries, are derived from Reticon spectra in the region 6005-6235 A at a scale of 7 km/s per diode. Cross-correlation of the spectra normally produces results accurate to better than 1.0 km/s. Eight new radial velocity variables are found (HR 2786, R Pup, HR 3291, HR 4451, HD 114520, HR 5667, HR 7014, and Nu1 Sgr). Improved orbits are determined for 15 known spectroscopic binaries, and provisional orbits are obtained for seven new spectroscopic binaries.
    Keywords: ASTRONOMY
    Type: Astrophysical Journal Supplement Series (ISSN 0067-0049); 53; 553-571
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    Infrared observations of RS CVn stars (1983)
    In:  Other Sources
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    Publication Date: 2011-08-18
    Description: The paper presents infrared photometry of the RS CVn binary stars AR Lac (1.2-10 microns) and MM Her (1.2-3.5 microns) as they egressed from their primary and secondary eclipses; of the eclipsing systems RS CVn and Z Her at maximum light (1.2-10 microns) and of the non-eclipsing systems UX Ari and HR 1099 (1.2-10 microns). An analysis of these and published V data based on flux ratio diagrams (linear analogues of color-color diagrams) shows that G and K stars supply the infrared light of these systems. In AR Lac, the combined light of a G5-K0 subgiant and either a late F dwarf or an early F subgiant can account for the observed visual and infrared light curves. None of these systems shows infrared emission from circumstellar matter. This result is simply understood: dust grains would not be expected to form in the physical conditions surrounding the subgiant, and the corona and chromosphere (whose properties have been deduced from spectroscopic X-ray observations) should not produce appreciable infrared emission.
    Keywords: ASTRONOMY
    Type: Royal Astronomical Society, Monthly Notices (ISSN 0035-8711); 205; 859-873
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    Ultraviolet high-resolution spectroscopy from the Space Telescope (1983)
    In:  Other Sources
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    Publication Date: 2011-08-18
    Description: The High Resolution Spectrograph is one of five scientific instruments which will be part of the Space Telescope observatory. The spectrograph was designed to take advantage of the imaging and pointing capabilities of the telescope to obtain ultraviolet spectra with spectral resolution comparable to large, ground-based coudeinstruments. Some of the results of the ground-based testing program will be described, along with applications of these properties to future science programs.
    Keywords: ASTRONOMY
    Type: Astronomical Society of the Pacific, Publications (ISSN 0004-6280); 95; 543-549
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    Theoretical studies of the effects of grain noise on photographic stellar astrometry and photometry (1983)
    In:  Other Sources
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    Publication Date: 2011-08-18
    Description: A method of incorporating the effects of photographic emulsion grain noise into digital image centering algorithms is presented which improves the accuracy of the derived stellar positions and magnitudes. Theoretical formulae are then derived for the limiting error of the center, and the photometric parameters. For IIIa-J, this error is 0.2-0.3 mu for bright unsaturated images, which agrees quite well with measurements made with the Yale PDS microdensitometer. It is expected that, with further improvements in the positional accuracy of the PDS, it should be possible to reach the emulsion grain noise limit, providing that emulsion shifts or other large scale errors do not dominate. It is also shown that, with appropriate trimming, marginal distribution image centering algorithms can yield an accuracy only slightly poorer than that obtained with two-dimensional distributions.
    Keywords: ASTRONOMY
    Type: Astronomical Journal (ISSN 0004-6256); 88; 1683-168
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  • 64
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    An improved celestial radio reference frame: JPL 1982-4 (1983)
    In:  Other Sources
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    Publication Date: 2011-08-18
    Description: In the development of a celestial radio reference frame, there are now over 100 sources whose relative positions are known with an average uncertainty less than 5 milliarcseconds. These sources are fairly uniformly distributed over the celestial sphere north of -40 deg declination. Their positions are expressed in the new IAU system. This presentation describes the analysis involved in obtaining these results, as well as future plans for linking this system to the JPL planetary ephemerides.
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  • 65
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    New infrared observations of IRS1, IRS3, and the adjacent nebula in the OMC-2 cluster (1984)
    In:  Other Sources
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    Publication Date: 2011-08-18
    Description: Observations of the infrared cluster of low luminosity protostars in Orion Molecular Cloud 2 (OMC2) are reported. Results show that the asymmetric distribution of the extended emission seen about IRS1 is another infrared reflection nebula. Energy distributions show that the spectral shape is fairly constant throughout the nebula which indicates there is little internal extinction within this region. Integrated surface brightness values show that the nebula is 5 times brighter than IRS1 at K. Energy distributions show that IRS1 has a more pronounced ice band absorption feature at 3.1 micron; suggesting that there is more extinction along the direct line of sight to IRS1 than along a line from IRS1 to the scattering grains and then to the observer. The distribution of the extended emission around IRS1 is similar to the reflection nebula seen in NGC 7538 (Werner et al. 1979). The asymmetric shapes of the two nebulae are similar and in each case there is excess extinction along line of sight to the illuminating source.
    Keywords: ASTRONOMY
    Type: Royal Observatory Lab. and Observational Infrared Spectra of Interstellar Dust; p 162-166
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  • 66
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    Transient dips of Cygnus X-1 observed from Tenma (1984)
    In:  Other Sources
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    Publication Date: 2011-08-19
    Description: The transient intensity dips of the binary system Cyg X-1 have been observed, using the gas scintillation proportional counter (GSPC) array onboard the Tenma X-ray astronomy satellite. The duration of the dips was in the range from several seconds to 10 minutes, with several dips occurring as much as 15 h before the superior conjunction. Within the dips, complex structures were observed with time scales of several seconds, and, in at least one case, shorter than two seconds. For a dip lasting longer than 10 minutes, a high-quality spectrum was obtained which reveals the K-absorption edge of iron at 7.18 + or - 0.18 keV. On the basis of the observed absorption, it is suggested that the dips are caused by absorption due to relatively cool matter (less than about 30,000 k); the low-energy excess observed during the dips is due either to an extended soft X-ray emitting corona or to partial obscuration of the X-ray source by multiple blobs. From the time structure of the dip, a blob size of the order of 10 to the 9th cm is derived.
    Keywords: ASTRONOMY
    Type: Astronomical Society of Japan, Publications (ISSN 0004-6264); 36; 4, 19
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  • 67
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    IUE observations of the 'Butterfly' Nebula M2-9 (1984)
    In:  Other Sources
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    Publication Date: 2011-08-19
    Description: IUE observations of the peculiar 'Butterfy' nebula M2-9 indicate that it is not a normal planetary nebula. The ultraviolet spectrum is characterized by few emission lines and a weak continuum. Mg II 2800 A is the strongest emission line present and may be indicative of a binary nucleus. Lines of N v, Q I, N III, N IV, Si III, and C III are seen, but C IV and O III are conspicuous by their absence. T(e) = 10,250 + or - 400 K was determined for the core. Nitrogen in the core is found to be overabundant by about a factor of 5 over the solar value. M2-9 may be an object in the early stages of becoming a planetary nebula.
    Keywords: ASTRONOMY
    Type: Astrophysical Journal, Part 1 (ISSN 0004-637X); 287; 353-358
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  • 68
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    Cometary showers and unseen solar companions (1984)
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    Publication Date: 2011-08-19
    Description: The possibility that an invisible solar companion passing through the Oort cloud every 28 Myr precipitates a sufficiently high rate of cometary collisions with the earth to account for periodic mass species extinctions recorded in the fossil record is discussed. A Monte Carlo simulation shows that any hypothesized 'death star' with a 28 Myr orbit would experience an average 10 percent change in period per orbit. Production of an 18-fold increase in cometary impacts would be associated with a 0.055 probability that a 10 km nucleus would hit the earth in a shower once every 510 Myr, longer than the proposed extinction periodicity. However, if the death star orbit has a 0.6 eccentricity and the Oort cloud is sufficiently densely populated, a 2 billion comet shower may be possible. A survey of large terrestrial impact craters indicates that 6-12 craters with diameters over 10 km originated in periodic showers. The extinctions in any case occur at 26 Myr periods and cannot be correlated with the 33 Myr period of recrossing the galactic plane, or with any other known phenomena.
    Keywords: ASTRONOMY
    Type: Nature (ISSN 0028-0836); 312; 380; Rep
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  • 69
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    Evidence for material between Saturn's A and F rings from the Voyager 2 photopolarimeter experiment (1984)
    In:  Other Sources
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    Publication Date: 2011-08-19
    Description: The region in the Saturn system between the F ring and the outer edge of the A ring is an area that appears, in images from the imaging experiment, to be virtually devoid of material except for three small satellites. Near the orbit of 1980S28, Atlas - the innermost satellite - the Voyager Photopolarimeter Stellar Occultation data show a discontinuity in count rate which marks a boundary between the tenuous material near the outer edge of the A ring and the orbit of Atlas. The data pertaining to this region have been examined with the aid of statistics and models generated from other similar ring structures. It is concluded that the discontinuity is real, implying the existence of tenuous material of normal optical depth of 0.01 to 0.006 in this region.
    Keywords: ASTRONOMY
    Type: Icarus (ISSN 0019-1035); 60; 409-415
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  • 70
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    1984 AB - A unique Mars-crossing asteroid (1984)
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    Publication Date: 2011-08-19
    Description: Asteroid 1984 AB, discovered in January 1984, proved to be a unique object with a close dynamical relationship to Mars. A brief history of the discovery and subsequent 'evolution' of the orbit as it was refined is presented. The preliminary orbit of 1984 AB indicated that it might be a Mars Trojan, and an extended discussion of this interesting possibility is presented, but this hypothesis had to be dismissed after further observations had refined the orbit. The semimajor axis and orbital eccentricity are very similar to that of Mars. No other known Mars-crossing asteroid exists with an orbit as closely associated to Mars.
    Keywords: ASTRONOMY
    Type: Icarus (ISSN 0019-1035); 60; 404-408
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  • 71
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    A radar study of Comet IRAS-Araki-Alcock 1983d (1984)
    In:  Other Sources
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    Publication Date: 2011-08-19
    Description: Radar echoes from Comet IRAS-Araki-Alcock at wavelengths 3.54 and 12.9 cm indicate that the comet's nucleus is very rough on a scale larger than the radar wavelengths; however, the low polarization ratio (25 percent at 3.54 cm) indicates that the scattering is not dominated by multiple reflections, internal reflections, or large abundances of sharp edges, cracks, and pits. The shape of the nucleus probably departs greatly from a sphere with average radii near 3-4 km. The nucleus does not appear to look significantly different from a number of Apollo and Amor asteroids except that: (1) there is a suggestion that minor structure moves rapidly across the spectra, and (2) the debris not gravitationally bound to the comet was detected, and contributes 25 percent of the total radar cross section at the 12.9-cm wavelength. Other considerations suggest that the pole was at least 45 deg away from the line of sight on two days of observation, and that the rotation period is approximately 1-2 days.
    Keywords: ASTRONOMY
    Type: Astronomical Journal (ISSN 0004-6256); 89; 1745-175
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  • 72
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    A solar spectral line list between 10 and 200 A modified for application to high spectral resolution X-ray astronomy (1984)
    In:  Other Sources
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    Publication Date: 2011-08-19
    Description: A spectral line list for the 10-200 A range is developed from existing solar spectra for application to high spectral resolution measurements of astrophysical plasmas. The solar spectral line lists are merged into a single comprehensive list. The effect of the solar emission measure distribution is removed from the line intensities, which results in a set of emission rates for the lines that can be applied to many optically thin, low density high temperature plasmas in ionization equilibrium. In addition to the measured solar lines, 250 theoretical lines are added to this list. These lines fall in wavelength regions where the existing solar lists have few lines because of limitations in instrumental sensitivity. Also, some lines have been added because the sun has very little plasma at temperatures of about one million K, and consequently these lines are weak or absent in solar spectra. The entire list contains about 600 lines. Finally, predicted spectra of the two RS CVn stars, alpha Aur (Capella) and UX Ari, are presented at 1 and 0.25 A spectral resolution. Also, the solar spectrum is shown at 1 A resolution, and the emission rate spectrum (spectrum not modified by an emission measure distribution) is shown at very high spectral resolution. The predicted spectra for Capella and UX Ari are based on results obtained from the Einstein and International Ultraviolet Explorer (IUE) spacecraft.
    Keywords: ASTRONOMY
    Type: Astrophysical Journal Supplement Series (ISSN 0067-0049); 56; 67-89
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  • 73
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    Comets (1981)
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    Publication Date: 2011-08-18
    Description: The nature and origin of comets is discussed. Observations of the principal parts of comets, the dust and plasma tails, the hydrogen cloud, the coma and the cometary nucleus, are presented, and the icy conglomerate model of Whipple as extended by Delsemme accounting for the observed properties and their variation with heliocentric distance is examined. The origin of comets is considered in relation to the orbital statistics of the long-period comets and the existence of the Oort cloud on the edge of the solar system, and possible roles for comets in the solar nebula and the evolution of the solar system are indicated. Particular attention is then given to the discovery and properties of Halley's Comet, which is expected to reach perihelion in 1986, and to possible flyby and rendezvous missions to Halley's Comet and others.
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  • 74
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    Electron densities for 10 planetary nebulae derived from the semiforbidden C III lambda 1907/1909 ratio. II (1981)
    In:  Other Sources
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    Publication Date: 2011-08-18
    Description: Electron densities for IC 351, IC 2165, J900, IC 3568, NGC 6644, NGC 6891, IC 4997, NGC 7009, Hu 1-2, and IC 5217 are derived from high-dispersion semiforbidden C III spectrograms. For seven of these nebulae, the derived electron density is larger than the values derived from either surface brightness measurements or forbidden line ratios. Only one object, Hu 1-2, shows pronounced splitting of the semiforbidden C III emission lines due to a large expansion velocity.
    Keywords: ASTRONOMY
    Type: Astrophysical Journal; vol. 246
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  • 75
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    Medium energy gamma ray astronomy with transpacific balloon flights (1981)
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    Publication Date: 2011-08-18
    Description: Transpacific balloon flights with the University of California, Riverside (UCR) double scatter telescope are discussed. With flight durations from 5 days up to perhaps 15 days the long observation times necessary for medium energy (1-30 MeV) gamma ray astronomy can be obtained. These flights would be made under the auspices of the Joint U.S.-Japan Balloon Flight Program at NASA. It is proposed that flights can provide at least 30 hours of observation time per flight for many discrete source candidates and 120 hours for detecting low intensity cosmic gamma ray bursts.
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  • 76
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    Studies in astronomical time series analysis. I - Modeling random processes in the time domain (1981)
    In:  Other Sources
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    Publication Date: 2011-08-18
    Description: Several random process models in the time domain are defined and discussed. Attention is given to the moving average model, the autoregressive model, and relationships between and combinations of these models. Consideration is then given to methods for investigating pulse structure, procedures of model construction, computational methods, and numerical experiments. A FORTRAN algorithm of time series analysis has been developed which is relatively stable numerically. Results of test cases are given to study the effect of adding noise and of different distributions for the pulse amplitudes. A preliminary analysis of the light curve of the quasar 3C 272 is considered as an example.
    Keywords: ASTRONOMY
    Type: Astrophysical Journal Supplement Series; 45; Jan. 198
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  • 77
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    Three new 'nonterrestrial' molecules (1981)
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    Publication Date: 2011-08-18
    Description: Eight new interstellar lines have been detected from three molecules not previously observed spectroscopically in space or in the laboratory. One is a linear or nearly linear molecule with microwave constants B0 equals 21,337.15 plus or minus 0.06 MHz, D0 equals 21.4 plus or minus 1.5 kHz. This is the thioformyl ion HCS(plus), first identified because B0 and D0 are close to those calculated, and now confirmed by laboratory detection of one of the present lines (Gudeman et al.). The second molecule, also linear or nearly so, has microwave constants B0 equals 10,691,406 plus or minus 0.043 MHz, D0 equals 1.84 plus or minus 0.91 kHz close to those expected for the isoelectronic systems HOCO(plus) and HOCN; a choice between the two cannot be made on the basis of the available astronomical data. The existence of a third molecule is deduced from an unidentified line at 85,338 MHz that has been found in many sources, is fairly intense in several, and may be self-absorbed in Sgr B2.
    Keywords: ASTRONOMY
    Type: Astrophysical Journal; vol. 246
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  • 78
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    Discovery of phase-locked variable polarization in an RS Canum Venaticorum-like star, HR 5110 (1981)
    In:  Other Sources
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    Publication Date: 2011-08-18
    Description: Using measurements on 79 nights in 1980 January-August, it is established that the polarization in the ultraviolet (U band) varies synchronously on the known binary period of 2.6132 days, with a peak-to-peak amplitude of 0.03%. The pattern is mainly second harmonic in character, as typical of binary star examples such as Algol and Upsilon Her. Reflection by the cooler star, by a plasma concentration, or both, is suggested. The scale of the polarization seems to be consistent with Rayleigh scattering by neutral hydrogen on the cooler star, and a roughly lambda to the -4th wavelength dependence should be searched for. The QU curve suggests a sizeable inclination for the system, of about 45 deg, but this is preliminary. Separately, a possible weak periodicity might be present on a subsidiary period, conceivably related to a rotating star spot.
    Keywords: ASTRONOMY
    Type: Astrophysical Journal; vol. 246
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  • 79
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    The 45 micron H2O ice band in the Kleinmann-Low Nebula (1981)
    In:  Other Sources
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    Publication Date: 2011-08-18
    Keywords: ASTRONOMY
    Type: Astrophysical Journal; vol. 245
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  • 80
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    Concerning the Wolf-Rayet and other luminous early-type stars (1981)
    In:  Other Sources
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    Publication Date: 2011-08-18
    Description: Effective temperatures, radii, and luminosities were determined from S2/68, ANS, UBV, and uvby photometry for four B0/B1 supergiants, four O4 stars, and four WN7/WN8 stars as well as for four test stars having spectral types between B1.5 V and 09 V and five stars with known angular diameters and effective temperatures. The effective temperatures of B1 Ia+ stars are found to be near 17,000 K, those of O4 stars near 45,000, and those of WN7/WN8 stars near 26,000 K. The question of modeling the atmospheres of hot luminous stars is examined, and it is noted that the photosphere can be modeled adequately using a classical plane-parallel layer model atmosphere. In addition, it is found that the Wolf-Rayet stars of types WN7/WN8 fall in the H-R diagram near the B0 Ia stars, while the others fall near B0.5 III stars. The evolutionary relationship between the Wolf-Rayet and O stars is considered; it is suggested that a Wolf-Rayet spectrum is a short-lived phase in the life of a massive star.
    Keywords: ASTRONOMY
    Type: Astrophysical Journal; vol. 244
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  • 81
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    Observation of the core of the Perseus cluster with the Einstein solid state spectrometer - Cooling gas and elemental abundances (1981)
    In:  Other Sources
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    Publication Date: 2011-08-18
    Description: Solid State Spectrometer observations of the core of the Perseus cluster have resulted in the detection of X-ray emission lines due to Si, S, and Fe. Analysis of the spectrum indicates that the X-ray emission has at least two characteristic temperatures. This is interpreted in the framework of radiative accretion in the core of the cluster. The derived parameters are a cooling time less than or approximately equal to 2 x 10 to the ninth years for the low-temperature gas, a mass accretion rate of approximately 300 solar masses per year, and a characteristic size of 10-20 kpc for the cool gas. The Fe abundance in the core (approximately 0.4) is similar to the Fe abundance averaged over the whole cluster, indicating that Fe emission is not strongly concentrated about NGC 1275. The Si and S abundances are consistent with solar values.
    Keywords: ASTRONOMY
    Type: Astrophysical Journal; vol. 244
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  • 82
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    Non-linear stability around the triangular libration points (1981)
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    Publication Date: 2011-08-18
    Description: The configuration space around the triangular libration points in the Earth-Moon system is partitioned according to the stability of the motion. The regions around L4 and L5 are established where particles placed with zero initial velocity will librate. The complexity of the partitioning is revealed.
    Keywords: ASTRONOMY
    Type: Celestial Mechanics; 23; Mar. 198
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  • 83
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    High-resolution observations of the QSO 3C 345 at 1.3 centimeters (1981)
    In:  Other Sources
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    Publication Date: 2011-08-18
    Description: High-resolution VLBI observations made at a frequency of 22.235 GHz of the quasar 3C 345 are discussed. Antennas located at the Crimean Astrophysical Observatory, USSR; Onsala, Sweden; Effelsberg, West Germany; and the Haystack Observatory, Massachusetts were employed at 4-min integration times to provide baselines ranging up to 5.5 x 10 to the 8th wavelengths. About 40% of the total flux density of 7.85 Jy, observed in November 1977, and 8.05 Jy, observed in October 1978, is found to originate in an unresolved component of the quasar core in a region less than 0.1 milliarcsec in diameter. The elongated jet-like component of the quasar is observed to contain several peaks of emission extending up to 6 milliarsec from the core which decreased in extent between the two observations.
    Keywords: ASTRONOMY
    Type: Astrophysical Journal; vol. 243
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  • 84
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    Formation of the terrestrial planets (1980)
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    Publication Date: 2011-08-18
    Description: Two growth mechanisms are identified for the development of the terrestrial planets: (1) gravitational instability leading to a collapse, and (2) gravitational accumulation caused by two-body collisions and coherence. The presence of a dynamically-significant gas phase would not affect either mechanism. Theoretical expressions are presented for the production of giant gaseous protoplanets by gravitational instability within a central dust layer. Gravitational accumulation is discussed with reference to the accumulation of planetesimals from a gas-free circumsolar swarm of bodies. Numerical simulations are given for the early stages of accumulation. The Safronov steady-state velocity is considered, noting that the competition between mutual collisional damping and gravitational acceleration by the members of a solar swarm yields a steady-state velocity distribution where the mean velocity is comparable to the escape velocity of the largest body. A time scale for accumulation is postulated on the basis of the radial distribution of a swarm of non-accreting bodies of equal size. The simultaneous gas-free accumulation of several terrestrial planets is noted. Attention is also given to growth mechanisms in gas-rich interplanetary media.
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  • 85
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    Is the remnant of SN 1006 Crablike (1980)
    In:  Other Sources
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    Publication Date: 2011-08-18
    Description: The solid-state spectrometer on the Einstein Observatory and the GSFC cosmic X-ray spectrometer on OSO 8 have observed the X-ray spectrum of SN 1006. The data can be well represented by a power-law model with alpha = 1.2, similar to the spectrum of the Crab Nebula. This is in contrast to the radio and X-ray maps of SN 1006 which show a shell structure more typical of SNR with thermal X-ray emission. The X-ray spectrum is suggestive of nonthermal synchrotron emission, raising the possibility that the remnant of SN 1006 contains a source of relativistic electrons.
    Keywords: ASTRONOMY
    Type: Astrophysical Journal; vol. 240
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  • 86
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    Radio astronomy (1981)
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    Publication Date: 2011-08-18
    Description: The activities of the Deep Space Network in support of radio astronomy operations during the first quarter of 1981 are reported. Results of the use of a low noise maser are presented, as well as updates in DSN support of experiments sanctioned by the Radio Astronomy Experiment Selection Panel.
    Keywords: ASTRONOMY
    Type: The Telecommun. and Data Acquisition Rept.; p 1-2
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  • 87
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    Radio observation of comet Meier /1978f/ in 18-cm OH lines (1980)
    In:  Other Sources
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    Publication Date: 2011-08-17
    Description: Observations of 18-cm OH spectral lines in comet Meier (1978f) with the 1000-ft. Arecibo telescope show spatial resolution of the OH coma by the 2.9 arcmin beam (=3.7 x 10 to the 5th km). The data agree with predictions of the solar Fraunhofer spectrum-pumping theory of comet OH excitation. On the assumption that the OH parent molecule (e.g., H2O) has a Haser-model scale length of about 1.0 x 10 to the 5th km at heliocentric distance 1 AU, an OH scale length of less than 10 to the 6th km, and probably near 1.0 x 10 to the 5th km is derived. Assuming a recently calculated value of the OH lifetime and the solar radiative pumping model, the results indicate an OH production rate of 10 to the 29th Kayser at heliocentric distance 2 AU.
    Keywords: ASTRONOMY
    Type: Astronomy and Astrophysics; 85; 1-2,; Sept
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  • 88
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    Near infrared photographic sky survey - A field index (1980)
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    Publication Date: 2011-08-17
    Description: The book presents an index of previously cataloged objects located in the fields of the northern sky included in the Steward Observatory Near Infrared Photographic Sky Survey, which was intended to be used for identification purposes in an effort to locate extremely red objects. The objects included in the index were taken from 16 catalogs of bright nebulae, dark nebulae, infrared objects, reflection nebulae, supernova remnants and other objects, and appear with their corresponding field numbers, computed field center coordinates, object name and 1950 epoch equatorial coordinates, as well as supplementary descriptive information as available. An appendix is also provided in which the center coordinates of each field are listed.
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  • 89
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    SS 433 - Intensive 4 month light curves (1980)
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    Publication Date: 2011-08-17
    Description: Photometry covering 100 nights during 1979 July-November is reported, in an unfiltered band (effectively 5200-8000 A), in a V band, and with a few measures in B. Correlation with the 13 day period of Crampton, Cowley, and Hutchings is found in the form of a double-peaked light curve. A more tentative connection with the 164 day 'precession' period suggested by a broad light minimum near a critical phase in the long cycle is found.
    Keywords: ASTRONOMY
    Type: Astrophysical Journal; vol. 238
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  • 90
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    Near infrared photography with a vacuum-cold camera (1980)
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    Publication Date: 2011-08-17
    Description: Sensitized cooled plates have been obtained of the Orion nebula region and of Sh2-149 in the wavelength ranges 8000 A-9000 A and 9,000 A-11,000 A with a recently designed and constructed vacuum-cold camera. Sensitization procedures are described and the camera design is presented.
    Keywords: ASTRONOMY
    Type: Astronomical Society of the Pacific; vol. 92
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  • 91
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    Stability of planetary orbits in binary systems (1980)
    In:  Other Sources
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    Publication Date: 2011-08-17
    Description: The possible existence of stable orbits is investigated in binary systems using Hill's method. Analytical stability conditions are established for satellites, for inner planets and for outer planets, allowing arbitrary values for the mass-ratio of the binary.
    Keywords: ASTRONOMY
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  • 92
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    On the capture of the Moon (1980)
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    Publication Date: 2011-08-17
    Description: This paper studies the possibility of lunar capture depending on variations of the solar mass under certain well specified conditions and assumptions regarding the behaviour of the three-body dynamical system formed by the Sun, Earth and Moon. It is found that a large amount of decrease in the solar mass (approximately 37%) would be required to allow capture if the model of the planar restricted problem of three bodies is assumed, if the masses of the Earth and Moon did not change and if the angular momentum of the Sun-Earth system did not change. Such large mass-changes of the Sun can not be associated with radiation mass losses only with catastrophic events, such as stellar close approaches.
    Keywords: ASTRONOMY
    Type: Celestial Mechanics; 21; Apr. 198
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  • 93
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    The time-of-flight system on the Goddard medium energy gamma-ray telescope (1980)
    In:  Other Sources
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    Publication Date: 2011-08-17
    Description: A scintillation counter time-of-flight system has been incorporated into the Goddard 50 cm by 50 cm spark chamber gamma-ray telescope. This system, utilizing constant fraction timing and particle position compensation, digitizes up to 10 ns time differences to six bit accuracy in less than 500 ns. Event selection decisions, discriminating against upward-moving particles, are made prior to spark chamber triggering. The performance of this system during a November 1978 balloon flight is discussed.
    Keywords: ASTRONOMY
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  • 94
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    Submillimetre astronomy from space platforms (1982)
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    Publication Date: 2011-08-18
    Description: The scientific need and the technical feasibility of a 10-m class far infrared telescope in space were studied and culminated in the recommendation of the large deployable reflector (LDR). The scientific considerations for such a project are described and the general characteristics of LDR are derived. A scientific program culminating in LDR is suggested.
    Keywords: ASTRONOMY
    Type: ESA The Sci. Importance of Submillimetre Observations ap 91-96 (SEE N83-22034 11-88)
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  • 95
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    High-resolution IUE observations of the 1981 eclipse of 32 CYG (1981)
    In:  Other Sources
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    Publication Date: 2011-08-18
    Description: 32 Cyg shows a spectacular pure emission line spectrum during eclipse. Six weeks later, most lines, which were observed in emission during eclipse, are seen as P Cygni type profiles with strong absorption components. The lines are formed through line scattering of B star light in the extended atmosphere (wind) of the K supergiant. During eclipse, the emission parts of the P Cyg lines remain visible since the size of the line scattering sphere around the B star is larger than the red giant. Other emission lines are formed in a shock front near the B star (CIV, SiIV, FeIII) and possibly in an accretion disk. The strong FeII UV Mult. 191 lambda lambda 1785-88 A is shown to be formed through optical pumping via FeII UV Mult. 9 photons. The phase dependence of the P Cyg type profiles is modelled by means of line transfer calculations in nonspherical, 3-dimensional geometry with velocity fields.
    Keywords: ASTRONOMY
    Type: Smithsonian Astrophysics Observatory 2nd Cambridge Workshop on Cool Stars, Stellar Systems, and the Sun, Vol. 1; p 245-259
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  • 96
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    A simple criterion for determining the dynamical stability of three-body systems (1982)
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    Publication Date: 2011-08-18
    Description: Coplanar, prograde three-body systems (TBS) are discussed, emphasizing the specification of general criteria for determining whether such systems are dynamically stable. It is shown that the Graziani-Black (1981) criteria provide a quantitatively accurate characterization of the onset of dynamic instability for values of the dimensionless mass ranging from one millionth to one million. Harrington's (1977) general criterion and the Graziani-Black criterion are compared with results from analytic work that spans a 12-orders-of-magnitude variation in the mass ratios of the TBS components. Comparison of the Graziani-Black criteria with data for eight well-studied triple-star systems indicates that the observed lower limit for the ratio of periastron distance of the tertiary orbit to the semimajor axis of the binary orbit is due to dynamical instability rather than to cosmogonic processes.
    Keywords: ASTRONOMY
    Type: Astronomical Journal; 87; Sept
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  • 97
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    A 1400-MHz survey of 1478 Abell clusters of galaxies (1982)
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    Publication Date: 2011-08-18
    Description: Observations of 1478 Abell clusters of galaxies with the NRAO 91-m telescope at 1400 MHz are reported. The measured beam shape was deconvolved from the measured source Gaussian fits in order to estimate the source size and position angle. All detected sources within 0.5 corrected Abell cluster radii are listed, including the cluster number, richness class, distance class, magnitude of the tenth brightest galaxy, redshift estimate, corrected cluster radius in arcmin, right ascension and error, declination and error, total flux density and error, and angular structure for each source.
    Keywords: ASTRONOMY
    Type: Astronomical Journal; 87; Aug. 198
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  • 98
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    IUE observations of proto-planetary and variable planetary nebulae. I - V1016 Cygni, HM Sagittae, and HBV 475. II - A search for variability in IC 4997 and NGC 6905 (1982)
    In:  Other Sources
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    Publication Date: 2011-08-18
    Description: The IUE satellite has undertaken UV observations of the proto-planetary nebulae V1016 Cyg, HM Sge, and HBV 475, yielding emission line fluxes, line ratios, line profiles, electron densities, and distances from these objects. While levels of increasing excitation and ionization as a function of time are shown by the data for the first two nebulae, the trend for HBV 475 is found to lead in the opposite direction. The formation of a shell is suggested by dramatic changes in the HM Sge UV line profiles over the last four years, including the disappearance of W-R features and the incipient splitting of the semi-forbidden C III 1909 A line. An additional IUE search for UV variability in the planetary nebulae IC 4997 and NGC 6905 has yielded emission line fluxes, line ratios and profiles, and central star temperatures, as well as stratification effects data for several ions in NGC 6905
    Keywords: ASTRONOMY
    Type: Astrophysical Journal; vol. 258
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  • 99
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    Periodic orbits of the elliptic restricted problem for the Sun-Jupiter-Saturn system (1982)
    In:  Other Sources
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    Publication Date: 2011-08-18
    Description: A systematic approach to generate periodic orbits in the elliptic restricted problem of three bodies is introduced. The approach is based on (numerical) continuation from periodic orbits of the first and second kind in the circular restricted problem to periodic orbits in the elliptic restricted problem. Two families of periodic orbits of the elliptic restricted problem are found by this approach. The mass ratio of the primaries of these orbits is equal to that of the Sun-Jupiter system. The sidereal mean motions between the infinitesimal body and the smaller primary are in a 2:5 resonance, so as to approximate the Sun-Jupiter-Saturn system. The lineaar stabilities of these periodic orbits are studied as functions of the eccentricities of the primaries and of the infinitesimal body. The results show that both stable and unstable periodic orbits exist in the elliptic restricted problem that are close to the actual Sun-Jupiter-Saturn system. However, the periodic orbit closest to the actual Sun-Jupiter-Saturn system is (linearly) stable.
    Keywords: ASTRONOMY
    Type: Celestial Mechanics; 27; May 1982
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  • 100
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    Sky input horn for a far-infrared interferometer (1982)
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    Publication Date: 2011-08-18
    Description: A unique design has been developed whereby a compound parabolic concentrator (CPC) and a compound elliptical concentrator (CEC) are joined at their throats. The CPC serves as the field-defining optics, in that it accepts up to a certain maximum acceptance angle and then concentrates this accepted energy at its throat. Energy incident from angles greater than the acceptance angle is rejected. The CEC takes the energy concentrated at the CPC throat and then redirects this energy into a finite-sized pupil a given distance away. The considered design will be used as the sky input horn for a cryogenic far-infrared polarizing interferometer to be flown on NASA's Cosmic Background Explorer satellite. The interferometer will operate at 2 K and measure the 3-K cosmic background radiation of the universe in the 100-micrometer-1-cm spectral range.
    Keywords: ASTRONOMY
    Type: Optics Letters; 7; May 1982
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