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  • Chemistry  (44,126)
  • Analytical Chemistry and Spectroscopy  (4,318)
  • EARTH RESOURCES AND REMOTE SENSING  (3,277)
  • ASTROPHYSICS  (2,970)
  • Magnetism
  • 1980-1984  (39,964)
  • 1925-1929
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Year
  • 1
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    Rational approaches to chemotherapy: antisickling agents (1981)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1981-08-14
    Description: 〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Klotz, I M -- Haney, D N -- King, L C -- New York, N.Y. -- Science. 1981 Aug 14;213(4509):724-31.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/7256275" target="_blank"〉PubMed〈/a〉
    Keywords: Anemia, Sickle Cell/*drug therapy ; Aspirin/analogs & derivatives/therapeutic use ; Chemical Phenomena ; Chemistry ; *Hemoglobin, Sickle ; Humans ; Protein Binding/drug effects ; Protein Conformation ; Salicylates/*therapeutic use ; Solubility ; Structure-Activity Relationship
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
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  • 2
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    Alpha-substituted gamma-butyrolactones: new class of anticonvulsant drugs (1982)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1982-09-10
    Description: Alkyl-Substituted gamma-butyrolactones were synthesized and tested for their convulsant and anticonvulsant actions in mice and guinea pigs. The alpha-substituted compounds, alpha, alpha-dimethyl-, and alpha-ethyl-alpha-methyl-gamma-butyrolactone were anticonvulsant compounds with a spectrum of activity similar to that of ethosuximide. In contrast, beta-substituted compounds were convulsant agents similar to picrotoxinin. The alpha-substituted-gama-butyrolactones represent a new class of anticonvulsant drug with experimental and clinical potential.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Klunk, W E -- McKeon, A -- Covey, D F -- Ferrendelli, J A -- GM-07200/GM/NIGMS NIH HHS/ -- GM-24483/GM/NIGMS NIH HHS/ -- NS-14834/NS/NINDS NIH HHS/ -- etc. -- New York, N.Y. -- Science. 1982 Sep 10;217(4564):1040-2.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/6810462" target="_blank"〉PubMed〈/a〉
    Keywords: *4-Butyrolactone/analogs & derivatives/*therapeutic use/toxicity ; Animals ; *Anticonvulsants ; Chemical Phenomena ; Chemistry ; Convulsants ; Drug Evaluation, Preclinical ; Electroencephalography ; Epilepsy, Absence/drug therapy ; Ethosuximide/pharmacology ; *Furans/*therapeutic use ; Guinea Pigs ; Mice ; Structure-Activity Relationship ; Trimethadione/pharmacology
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  • 3
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    Phase transition and crystal structure of the 37 degrees C form of cholesterol (1983)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1983-05-06
    Description: Crystalline cholesterol undergoes a phase transition a few degrees below human body temperature. The high-temperature form has an unusually complex structure with 16 independent molecules. In the transition two molecules change side chain conformation, four reorient about their long axes, and ten remain unchanged. The transition mechanism implies relatively nonspecific intermolecular interactions, qualitatively consistent with the behavior of cholesterol in biomembranes. The transition preserves a remarkably closely obeyed pseudosymmetry present in the structure.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Hsu, L Y -- Nordman, C E -- GM15259/GM/NIGMS NIH HHS/ -- New York, N.Y. -- Science. 1983 May 6;220(4597):604-6.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/6836303" target="_blank"〉PubMed〈/a〉
    Keywords: Body Temperature ; Chemical Phenomena ; Chemistry ; *Cholesterol ; Crystallization ; Humans ; Magnetic Resonance Spectroscopy ; Molecular Conformation
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  • 4
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    Cytochrome a3 structure in carbon monoxide-bound cytochrome oxidase (1984)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1984-07-20
    Description: The iron-carbon monoxide stretching mode and the iron-carbon-oxygen bending mode in carbon monoxide-bound cytochrome oxidase have been assigned at 520 and 578 cm-1, respectively. The frequencies, widths, and intensities of these modes show that the Fe-C-O grouping in carbon monoxide-cytochrome a3 is linear but tilted from the normal to the heme plane; that the iron-histidine bond in both five- and six-coordinate cytochrome a3 is strained; and that the carbon monoxide and the proximal histidine each have characteristic, well-defined orientations in all molecules. These data can account for the binding affinities of carbon monoxide and dioxygen under physiological conditions.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Argade, P V -- Ching, Y C -- Rousseau, D L -- New York, N.Y. -- Science. 1984 Jul 20;225(4659):329-31.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/6330890" target="_blank"〉PubMed〈/a〉
    Keywords: Animals ; Carbon Monoxide/metabolism ; Cattle ; Chemical Phenomena ; Chemistry ; Electron Transport Complex IV/*metabolism ; Myoglobin/metabolism ; Oxidation-Reduction ; Oxygen/metabolism ; Spectrum Analysis, Raman
    Print ISSN: 0036-8075
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  • 5
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    Leukotrienes: mediators of immediate hypersensitivity reactions and inflammation (1983)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1983-05-06
    Description: Arachidonic acid plays a central role in a biological control system where such oxygenated derivatives as prostaglandins, thromboxanes, and leukotrienes are mediators. The leukotrienes are formed by transformation of arachidonic acid into an unstable epoxide intermediate, leukotriene A4, which can be converted enzymatically by hydration to leukotriene B4, and by addition of glutathione to leukotriene C4. This last compound is metabolized to leukotrienes D4 and E4 by successive elimination of a gamma-glutamyl residue and glycine. Slow-reacting substance of anaphylaxis consists of leukotrienes C4, D4, and E4. The cysteinyl-containing leukotrienes are potent bronchoconstrictors, increase vascular permeability in postcapillary venules, and stimulate mucus secretion. Leukotriene B4 causes adhesion and chemotactic movement of leukocytes and stimulates aggregation, enzyme release, and generation of superoxide in neutrophils. Leukotrienes C4, D4, and E4, which are released from the lung tissue of asthmatic subjects exposed to specific allergens, seem to play a pathophysiological role in immediate hypersensitivity reactions. These leukotrienes, as well as leukotriene B4, have pro-inflammatory effects.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Samuelsson, B -- New York, N.Y. -- Science. 1983 May 6;220(4597):568-75.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/6301011" target="_blank"〉PubMed〈/a〉
    Keywords: Animals ; Arachidonic Acids/metabolism/pharmacology/physiology ; Bronchi/drug effects ; Cats ; Chemical Phenomena ; Chemistry ; Cricetinae ; Guinea Pigs ; Haplorhini ; Humans ; Hypersensitivity, Immediate/*physiopathology ; Inflammation/*physiopathology ; Leukocytes/drug effects/metabolism ; Leukotriene B4/pharmacology/*physiology ; Mice ; Microcirculation/drug effects ; Rabbits ; Rats ; SRS-A/*physiology
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  • 6
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    Amphiphilic secondary structure: design of peptide hormones (1984)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1984-01-20
    Description: Peptide synthesis can be used for elucidating the roles of secondary structures in the specificity of hormones, antigens, and toxins. Intermediate sized peptides with these activities assume amphiphilic secondary structures in the presence of membranes. When models are designed to optimize the amphiphilicity of the secondary structure, stronger interactions can be observed with the synthetic peptides than with the naturally occurring analogs.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Kaiser, E T -- Kezdy, F J -- HL-18577/HL/NHLBI NIH HHS/ -- New York, N.Y. -- Science. 1984 Jan 20;223(4633):249-55.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/6322295" target="_blank"〉PubMed〈/a〉
    Keywords: Amino Acid Sequence ; Apolipoprotein A-I ; Apolipoproteins ; Binding Sites ; Calcitonin ; Chemical Phenomena ; Chemistry ; Corticotropin-Releasing Hormone ; Endorphins ; Glucagon ; Growth Hormone-Releasing Hormone ; *Hormones/pharmacology ; Lipoproteins, HDL ; Melitten ; Models, Structural ; *Peptides/chemical synthesis/metabolism/pharmacology ; Protein Conformation ; Structure-Activity Relationship ; beta-Endorphin
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  • 7
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    Fourier transform mass spectrometry (1984)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1984-10-19
    Description: Fourier transform mass spectrometry will play an important role in the future because of its unique combination of high mass resolution, high upper mass limit, and multichannel advantage. These features have already found application in gas chromatography-mass spectrometry, multiphoton ionization, laser desorption, and secondary ion mass spectrometry. However, its most notable feature is the ability to store ions. This characteristic, when combined with the others, will allow expeditious study of the interaction of gas-phase ions with both photons (photodissociation) and neutral molecules, and the convenient application of this fundamental information for chemical analysis.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Gross, M L -- Rempel, D L -- 2-8423576/PHS HHS/ -- New York, N.Y. -- Science. 1984 Oct 19;226(4672):261-8.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/6385250" target="_blank"〉PubMed〈/a〉
    Keywords: Chemical Phenomena ; Chemistry ; *Fourier Analysis ; Ions ; Lasers ; *Mass Spectrometry/instrumentation/methods
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  • 8
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    Studying enzyme mechanism by 13C nuclear magnetic resonance (1984)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1984-08-31
    Description: High-resolution carbon-13 nuclear magnetic resonance (NMR) spectra of enzyme-inhibitor and enzyme-substrate complexes provide detailed structural and stereochemical information on the mechanism of enzyme action. The proteases trypsin and papain are shown to form tetrahedrally coordinated complexes and acyl derivatives with a variety of compounds artificially enriched at the site or sites of interest. These results are compared with the structural information derived from x-ray diffraction. Detailed NMR studies have provided a clearer picture of the ionization state of the residues participating in enzyme-catalyzed processes than other more classical techniques. The dynamics of enzymic catalysis can be observed at sub-zero temperatures by a combination of cryoenzymology and carbon-13 NMR spectroscopy. With these powerful techniques, transient, covalently bound intermediates in enzyme-catalyzed reactions can be detected and their structures rigorously assigned.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Mackenzie, N E -- Malthouse, J P -- Scott, A I -- New York, N.Y. -- Science. 1984 Aug 31;225(4665):883-9.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/6433481" target="_blank"〉PubMed〈/a〉
    Keywords: Binding Sites ; Carbon Isotopes ; Carboxypeptidases/metabolism ; Carboxypeptidases A ; Catalysis ; Chemical Phenomena ; Chemistry ; Coenzymes/*metabolism ; Endopeptidases/metabolism ; Enzymes/*metabolism ; Freezing ; Fructose-Bisphosphate Aldolase/metabolism ; Magnetic Resonance Spectroscopy ; Papain/metabolism ; Pepsin A/metabolism ; Peptide Hydrolases/*metabolism ; Protease Inhibitors ; Pterins/metabolism ; Pyridoxal Phosphate/metabolism ; Serine Endopeptidases
    Print ISSN: 0036-8075
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  • 9
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    What is the risk from chlorofluorocarbons? (1984)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1984-03-09
    Description: 〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Maugh, T H 2nd -- New York, N.Y. -- Science. 1984 Mar 9;223(4640):1051-2.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/6695193" target="_blank"〉PubMed〈/a〉
    Keywords: *Air Pollutants ; *Atmosphere ; Carbon Tetrachloride ; Chemical Phenomena ; Chemistry ; *Chlorofluorocarbons, Methane ; Free Radicals ; Nitrogen Dioxide ; Nitrous Oxide ; Oxygen ; *Ozone ; Photochemistry ; Risk ; Singlet Oxygen ; Trichloroethanes ; Ultraviolet Rays
    Print ISSN: 0036-8075
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    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
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  • 10
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    Pyrolysis mass spectrometry of complex organic materials (1984)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1984-10-19
    Description: Pyrolysis mass spectrometry in combination with computerized multivariate statistical analysis enables qualitative and quantitative analysis of nonvolatile organic materials containing molecular assemblies of a complexity and size far beyond the capabilities of direct mass spectrometry. The state of the art in pyrolysis mass spectrometry techniques is illustrated through specific applications, including structural determination and quality control of synthetic polymers, quantitative analysis of polymer mixtures, classification and structural characterization of fossil organic matter, and nonsupervised numerical extraction of component patterns from complex biological samples.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Meuzelaar, H L -- Windig, W -- Harper, A M -- Huff, S M -- McClennen, W H -- Richards, J M -- New York, N.Y. -- Science. 1984 Oct 19;226(4672):268-74.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/6484572" target="_blank"〉PubMed〈/a〉
    Keywords: Biochemical Phenomena ; Biochemistry ; Chemical Phenomena ; Chemistry ; Coal ; Enterobacteriaceae/analysis/isolation & purification ; Hot Temperature ; Mass Spectrometry/*methods ; Polymers
    Print ISSN: 0036-8075
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  • 11
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    Lariat RNA's as intermediates and products in the splicing of messenger RNA precursors (1984)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1984-08-31
    Description: The splicing of messenger RNA precursors in vitro proceeds through an intermediate that has the 5' end of the intervening sequence joined to a site near the 3' splice site. This lariat structure, which has been characterized for an adenovirus 2 major late transcript, has a branch point, with 2'-5' and 3'-5' phosphodiester bonds emanating from a single adenosine residue. The excised intervening sequence retains the branch site and terminates in a guanosine residue with a 3' hydroxyl group. The phosphate group at the splice junction between the two exons originates from the 3' splice site at the precursor.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Padgett, R A -- Konarska, M M -- Grabowski, P J -- Hardy, S F -- Sharp, P A -- P01-CA14051/CA/NCI NIH HHS/ -- P01-CA26717/CA/NCI NIH HHS/ -- R01-GM32467/GM/NIGMS NIH HHS/ -- New York, N.Y. -- Science. 1984 Aug 31;225(4665):898-903.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/6206566" target="_blank"〉PubMed〈/a〉
    Keywords: Adenoviruses, Human/metabolism ; Base Sequence ; Chemical Phenomena ; Chemistry ; Nucleic Acid Conformation ; Nucleic Acid Precursors/analysis/*metabolism ; Oligoribonucleotides/metabolism ; Phosphates/metabolism ; RNA/analysis/*metabolism ; RNA Precursors ; *RNA Splicing ; RNA, Messenger/analysis/*metabolism ; RNA, Viral/analysis/*metabolism
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  • 12
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    beta-Carotene: an unusual type of lipid antioxidant (1984)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1984-05-11
    Description: The mechanism of lipid peroxidation and the manner in which antioxidants function is reviewed. beta-Carotene is a purported anticancer agent, which is believed by some to have antioxidant action of a radical-trapping type. However, definitive experimental support for such action has been lacking. New experiments in vitro show that beta-carotene belongs to a previously unknown class of biological antioxidants. Specifically, it exhibits good radical-trapping antioxidant behavior only at partial pressures of oxygen significantly less than 150 torr, the pressure of oxygen in normal air. Such low oxygen partial pressures are found in most tissues under physiological conditions. At higher oxygen pressures, beta-carotene loses its antioxidant activity and shows an autocatalytic, prooxidant effect, particularly at relatively high concentrations. Similar oxygen-pressure-dependent behavior may be shown by other compounds containing many conjugated double bonds.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Burton, G W -- Ingold, K U -- New York, N.Y. -- Science. 1984 May 11;224(4649):569-73.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/6710156" target="_blank"〉PubMed〈/a〉
    Keywords: Antioxidants/*metabolism ; Carotenoids/*metabolism ; Chemical Phenomena ; Chemistry ; Free Radicals ; Humans ; Linoleic Acids/metabolism ; *Lipid Metabolism ; Oxidation-Reduction ; Oxygen/metabolism ; Partial Pressure ; Peroxides/metabolism ; Tetrahydronaphthalenes/metabolism ; beta Carotene
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  • 13
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    Bromine residue at hydrophilic region influences biological activity of aplysiatoxin, a tumor promoter (1983)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1983-12-16
    Description: Aplysiatoxin and debromoaplysiatoxin, which are isolated from the seaweed, Lyngbya gracilis, differ in their chemical structure only by the presence or absence of a bromine residue in the hydrophilic region. The function and the structure-activity relation of the hydrophilic region are not known. Aplysiatoxin increased malignant transformation, stimulated DNA synthesis, and inhibited the binding of phorbol-12,13-dibutyrate and epidermal growth factor to cell receptors. Debromoaplysiatoxin inhibited the binding of these two substances as strongly as aplysiatoxin but did not increase malignant transformation or stimulate DNA synthesis. These results indicate that a slight change in the chemical structure of the hydrophilic region of aplysiatoxin affects its abilities to increase cell transformation and stimulate DNA synthesis and that the abilities of the tumor promoters to inhibit the binding of phorbol-12,13-dibutyrate and epidermal growth factor are dissociable from their abilities to increase cell transformation and stimulate DNA synthesis under some circumstances.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Shimomura, K -- Mullinix, M G -- Kakunaga, T -- Fujiki, H -- Sugimura, T -- New York, N.Y. -- Science. 1983 Dec 16;222(4629):1242-4.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/6316505" target="_blank"〉PubMed〈/a〉
    Keywords: Animals ; *Caenorhabditis elegans Proteins ; Carcinogens/*pharmacology ; Carrier Proteins ; Cell Line ; Cell Transformation, Neoplastic/*drug effects ; Chemical Phenomena ; Chemistry ; DNA/biosynthesis ; Epidermal Growth Factor/metabolism ; Lactones/analysis/*pharmacology ; *Lyngbya Toxins ; Mice ; Phorbol 12,13-Dibutyrate ; Phorbol Esters/metabolism ; *Protein Kinase C ; Receptor, Epidermal Growth Factor ; Receptors, Cell Surface/metabolism ; *Receptors, Drug ; Structure-Activity Relationship
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  • 14
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    Phenylalanine transfer RNA: molecular dynamics simulation (1984)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1984-03-16
    Description: Yeast phenylalanine transfer RNA was subjected to a 12-picosecond molecular dynamics simulation. The principal features of the x-ray crystallographic analysis are reproduced, and the amplitudes of atomic displacements appear to be determined by the degree of exposure of the atoms. An analysis of the hydrogen bonds shows a correlation between the average length of a bond and the fluctuation in that length and reveals a rocking motion of bases in Watson-Crick guanine X cytosine base pairs. The in-plane motions of the bases are generally of larger amplitude than the out-of-plane motions, and there are correlations in the motions of adjacent bases.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Harvey, S C -- Prabhakaran, M -- Mao, B -- McCammon, J A -- New York, N.Y. -- Science. 1984 Mar 16;223(4641):1189-91.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/6560785" target="_blank"〉PubMed〈/a〉
    Keywords: Chemical Phenomena ; Chemistry ; Computers ; Cytosine ; Guanine ; Hydrogen Bonding ; Nucleic Acid Conformation ; *RNA, Fungal ; *RNA, Transfer, Amino Acyl ; Yeasts/analysis
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  • 15
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    Reaction of the antitumor antibiotic CC-1065 with DNA: structure of a DNA adduct with DNA sequence specificity (1984)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1984-11-16
    Description: Sequence-dependent variations in DNA revealed by x-ray crystallographic studies have suggested that certain DNA-reactive drugs may react preferentially with defined sequences in DNA. Drugs that wind around the helix and reside within one of the grooves of DNA have perhaps the greatest chance of recognizing sequence-dependent features of DNA. The antitumor antibiotic CC-1065 covalently binds through N-3 of adenine and resides within the minor groove of DNA. This drug overlaps with five base pairs for which a high sequence specificity exists.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Hurley, L H -- Reynolds, V L -- Swenson, D H -- Petzold, G L -- Scahill, T A -- New York, N.Y. -- Science. 1984 Nov 16;226(4676):843-4.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/6494915" target="_blank"〉PubMed〈/a〉
    Keywords: Antibiotics, Antineoplastic/*metabolism ; *Base Sequence ; Binding Sites ; Chemical Phenomena ; Chemistry ; DNA/*metabolism ; *Indoles ; Leucomycins/*metabolism ; Molecular Conformation ; X-Ray Diffraction
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  • 16
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    Allylamine derivatives: new class of synthetic antifungal agents inhibiting fungal squalene epoxidase (1984)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1984-06-15
    Description: A new class of synthetic antifungal agents, the allylamines , has been developed by modification of naftifine , a topical antimycotic. SF 86-327, the most effective of these compounds so far, is highly active in vitro against a wide range of fungi and exceeds clinical standards in the oral and topical treatment of guinea pig dermatophytoses. SF 86-327 is a powerful specific inhibitor of fungal squalene epoxidase, a key enzyme in sterol biosynthesis.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Petranyi, G -- Ryder, N S -- Stutz, A -- New York, N.Y. -- Science. 1984 Jun 15;224(4654):1239-41.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/6547247" target="_blank"〉PubMed〈/a〉
    Keywords: Allylamine/analogs & derivatives/*chemical synthesis/pharmacology ; Amines/*chemical synthesis ; Animals ; Antifungal Agents/*chemical synthesis/pharmacology ; Chemical Phenomena ; Chemistry ; Dermatomycoses/drug therapy ; Fungi/*drug effects/enzymology ; Guinea Pigs ; Naphthalenes/chemical synthesis/pharmacology ; Oxygenases/*antagonists & inhibitors ; Squalene Monooxygenase
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    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
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    Disulfide bond engineered into T4 lysozyme: stabilization of the protein toward thermal inactivation (1984)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1984-11-02
    Description: By recombinant DNA techniques, a disulfide bond was introduced at a specific site in T4 lysozyme, a disulfide-free enzyme. This derivative retained full enzymatic activity and was more stable toward thermal inactivation than the wild-type protein. The derivative, T4 lysozyme (Ile3----Cys), was prepared by substituting a Cys codon for an Ile codon at position 3 in the cloned lysozyme gene by means of oligonucleotide-dependent, site-directed mutagenesis. The new gene was expressed in Escherichia coli under control of the (trp-lac) hybrid tac promoter, and the protein was purified. Mild oxidation generated a disulfide bond between the new Cys3 and Cys97, one of the two unpaired cysteines of the native molecule. Oxidized T4 lysozyme (Ile3----Cys) exhibited specific activity identical to that of the wild-type enzyme when measured at 20 degrees C in a cell-clearing assay. The cross-linked protein was more stable than the wild type during incubation at elevated temperatures as determined by recovered enzymatic activity at 20 degrees C.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Perry, L J -- Wetzel, R -- New York, N.Y. -- Science. 1984 Nov 2;226(4674):555-7.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/6387910" target="_blank"〉PubMed〈/a〉
    Keywords: Chemical Phenomena ; Chemistry ; DNA, Recombinant/metabolism ; Escherichia coli/enzymology ; *Genetic Engineering ; Kinetics ; Muramidase/*genetics/metabolism ; Protein Denaturation
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  • 18
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    DNA-binding proteins (1983)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1983-09-09
    Description: The structures of three proteins that regulate gene expression have been determined recently and suggest how these proteins may bind to their specific recognition sites on the DNA. One protein (Cro) is a repressor of gene expression, the second (CAP) usually stimulates gene expression, and the third (lambda repressor) can act as either a repressor or an activator. The three proteins contain a substructure consisting of two consecutive alpha helices that is virtually identical in each case. Structural and amino acid sequence comparisons suggest that this bihelical fold occurs in a number of proteins that regulate gene expression, and is an intrinsic part of the DNA-protein recognition event. The modes of repression and activation by Cro and lambda repressor are understood reasonably well, but the mode of action of CAP is still unclear.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Takeda, Y -- Ohlendorf, D H -- Anderson, W F -- Matthews, B W -- GM20066/GM/NIGMS NIH HHS/ -- GM28138/GM/NIGMS NIH HHS/ -- GM30894/GM/NIGMS NIH HHS/ -- New York, N.Y. -- Science. 1983 Sep 9;221(4615):1020-6.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/6308768" target="_blank"〉PubMed〈/a〉
    Keywords: Amino Acid Sequence ; Chemical Phenomena ; Chemistry ; *DNA Helicases ; DNA-Binding Proteins ; Escherichia coli/genetics ; Gene Expression Regulation ; Models, Chemical ; Protein Conformation
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  • 19
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    A nitrogen pressure of 50 atmospheres does not prevent evolution of hydrogen by nitrogenase (1984)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1984-06-08
    Description: The effect of a partial pressure of nitrogen of 50 atmospheres (5065 kilopascals ) on the hydrogen evolution reaction of nitrogenase has been investigated. Evolution of hydrogen was not blocked completely by 50 atmospheres of nitrogen in any of four experiments; rather, 27.3 +/- 2.4 percent of the total electron flux through nitrogenase was directed toward production of hydrogen. The ratio of hydrogen evolved to nitrogen fixed was close to 1:1, which implies that hydrogen evolution is obligatory in the fixation of molecular nitrogen by nitrogenase.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Simpson, F B -- Burris, R H -- AI-00848/AI/NIAID NIH HHS/ -- New York, N.Y. -- Science. 1984 Jun 8;224(4653):1095-7.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/6585956" target="_blank"〉PubMed〈/a〉
    Keywords: Chemical Phenomena ; Chemistry ; *Hydrogen ; *Nitrogen ; Nitrogen Fixation ; *Nitrogenase ; Partial Pressure
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  • 20
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    Nonvolatile mutagens in drinking water: production by chlorination and destruction by sulfite (1980)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1980-01-04
    Description: In concentrates of water produced in a laboratory simulation of a drinking water treatment process, direct-acting, nonvolatile mutagens were readily detected by means of the Ames Salmonella test. The mutagens were shown to be produced by the chlorination process. Treatment of the water with chloramine resulted in less mutagenic activity than treatment with free chlorine. Dechlorination of drinking water with sulfite sharply reduced the mutagenic activity. Treatment with sulfur dioxide is proposed as an effective, inexpensive method of reducing the direct-acting mutagenic activity of drinking water and of aqueous industrial effluents.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Cheh, A M -- Skochdopole, J -- Koski, P -- Cole, L -- New York, N.Y. -- Science. 1980 Jan 4;207(4426):90-2.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/6985746" target="_blank"〉PubMed〈/a〉
    Keywords: Chemical Phenomena ; Chemistry ; Chloramines ; Chlorine ; Mutagens/*analysis ; Salmonella typhimurium/genetics ; Sulfites ; Water Pollutants/*analysis ; Water Pollutants, Chemical/*analysis ; Water Supply/*analysis
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  • 21
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    Automated synthesis of gene fragments (1981)
    American Association for the Advancement of Science (AAAS)
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    Publication Date: 1981-10-16
    Description: The DNA/RNA Synthesizer provides a complete and automated procedure for the synthesis of DNA sequences. Each base unit is added in a 30-minute cycle, permitting a tetradecamer to be constructed in 6 1/2 hours. The complete procedure is described, including a practical procedure for isolation and purification of the desired DNA sequence.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Alvarado-Urbina, G -- Sathe, G M -- Liu, W C -- Gillen, M F -- Duck, P D -- Bender, R -- Ogilvie, K K -- New York, N.Y. -- Science. 1981 Oct 16;214(4518):270-4.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/6169150" target="_blank"〉PubMed〈/a〉
    Keywords: Automation ; Chemical Phenomena ; Chemistry ; DNA/*chemical synthesis ; *Genes, Synthetic ; RNA/*chemical synthesis ; Solubility
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  • 22
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    Chitin: New facets of research (1981)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1981-05-15
    Description: Research on chitin as a marine resource is pointing to novel applications for this cellulose-like biopolymer. Discovery of nondegrading solvent systems has permitted the spinning of filaments, for example, for use as surgical sutures. New methods for preparing the bioactive alkyl glycoside of N-acetyl-D-glucosamine (the monomer unit of chitin) and a microcrystalline chitin has encouraged their use as promoters for growth of bifidobacteria and as an aid in digestion of high-lactose cheese whey by domestic animals. Chitin-protein complexes of several crustacean species show great variability in ratios of chitin to covalently bound protein and in residual protein in the "purified" chitins.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Austin, P R -- Brine, C J -- Castle, J E -- Zikakis, J P -- New York, N.Y. -- Science. 1981 May 15;212(4496):749-53.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/7221561" target="_blank"〉PubMed〈/a〉
    Keywords: Animal Feed ; Animals ; Cheese ; Chemical Phenomena ; Chemistry ; Chickens ; *Chitin ; Crystallography ; Lactose/metabolism ; Proteins/analysis ; Sutures ; *Technology
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  • 23
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    DNA sequencing and gene structure (1981)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1981-12-18
    Description: 〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Gilbert, W -- New York, N.Y. -- Science. 1981 Dec 18;214(4527):1305-12.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/7313687" target="_blank"〉PubMed〈/a〉
    Keywords: Base Sequence ; Chemical Phenomena ; Chemistry ; DNA/*genetics ; Eukaryotic Cells/physiology ; *Genes ; Hydrazines ; Lac Operon ; Methylation ; Prokaryotic Cells/physiology ; Sulfuric Acid Esters
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  • 24
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    Boradeption: a new procedure for transferring water-insoluble agents across cell membranes (1982)
    American Association for the Advancement of Science (AAAS)
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    Publication Date: 1982-07-09
    Description: A new process has been developed which is called "Boradeption" to signify boronic acid--dependent phase transfer of water-insoluble agents. Highly fluorescent boronic acid dervatives, FluoroBoras, are solubilized with a physiologically compatible carrier buffer containing a receptor group for boronate adduct formation. The system can be used to stain living cells. In another variation of the Boradeption concept, an insoluble reporter molecule containing a boronate receptor is solubilized with a carrier buffer containing a boronic acid functional group. The boronate-receptor complexes, which are in dynamic equilibrium, can be designed as vital stains and reagents for a variety of biological and medical applications.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Gallop, P M -- Paz, M A -- Henson, E -- AG-00376-07/AG/NIA NIH HHS/ -- HL-20764-04A1/HL/NHLBI NIH HHS/ -- New York, N.Y. -- Science. 1982 Jul 9;217(4555):166-9.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/6178158" target="_blank"〉PubMed〈/a〉
    Keywords: Animals ; *Biological Transport ; *Boron Compounds/therapeutic use ; *Boronic Acids/therapeutic use ; *Cell Membrane Permeability ; Cells, Cultured ; Chemical Phenomena ; Chemistry ; Chromogenic Compounds/metabolism ; Cricetinae ; Fibroblasts ; Fluorescent Dyes/metabolism ; Humans ; Rats ; Staining and Labeling
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    Reversible chemical modification of the scrapie agent (1981)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1981-12-11
    Description: The scrapie agent causes a degenerative nervous system disease in sheep and goats. Studies with extensively purified preparations demonstrated that the agent contains a protein that is required for infectivity. Chemical modification of the scrapie agent by diethyl pyrocarbonate reduced the titer 1000-fold. Exposure of the inactivated agent to hydroxylamine, a strong nucleophile, resulted in complete restoration of infectivity. Presumably, nucleophilic residues within a scrapie agent protein undergo carbethoxylation on reaction with diethyl pyrocarbonate, and subsequent addition of hydroxylamine displaces these carbethoxy groups.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉McKinley, M P -- Masiarz, F R -- Prusiner, S B -- NS14069/NS/NINDS NIH HHS/ -- New York, N.Y. -- Science. 1981 Dec 11;214(4526):1259-61.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/6795721" target="_blank"〉PubMed〈/a〉
    Keywords: Animals ; Biological Assay ; Brain/microbiology ; Chemical Phenomena ; Chemistry ; Cricetinae ; Diethyl Pyrocarbonate/pharmacology ; Histidine/pharmacology ; *Prions ; Ribonucleases/pharmacology ; Serum Albumin, Bovine/pharmacology ; Viral Proteins/*isolation & purification/pharmacology
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    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
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  • 26
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    Nonenzymatic browning in vivo: possible process for aging of long-lived proteins (1981)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1981-01-30
    Description: The incubation of lens proteins with reducing sugars leads to the formation of fluorescent yellow pigments and cross-like similar to those reported in aging and cataractous human lenses. Called nonenzymatic browning or the Maillard reaction, this aging process also occurs in stored foods. Reducing sugars condense with the free amino group of proteins, then rearrange and dehydrate to form unsaturated pigments and cross-linked products. Although most proteins in living systems turn over with sufficient rapidity to avoid nonenzymatic browning, some, such as lens crystallins and skin collagen, are exceptionally long-lived and may be vulnerable.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Monnier, V M -- Cerami, A -- AM 19655/AM/NIADDK NIH HHS/ -- New York, N.Y. -- Science. 1981 Jan 30;211(4481):491-3.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/6779377" target="_blank"〉PubMed〈/a〉
    Keywords: *Aging ; Animals ; Cattle ; Chemical Phenomena ; Chemistry ; *Crystallins ; Diabetes Mellitus/physiopathology ; Glucose ; Glucosephosphates ; In Vitro Techniques ; Lysine ; *Proteins ; Spectrophotometry, Ultraviolet
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    The National Science Foundation looks to the future (1981)
    American Association for the Advancement of Science (AAAS)
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    Publication Date: 1981-03-13
    Description: Great advances have been made in fundamental scientific research in recent years. The new knowledge gathered, in addition to deepening our understanding of the physical universe, contributes a range of abilities and opportunities to society that would not otherwise be available. Much research that may be called applied because it addresses needs of society is quite fundamental in character, and support of such research at the National Science Foundation is to be handled in tandem by the research directorates. Other areas that require a refocusing of support are engineering science and education, at all levels, in science and engineering. Increasing our strength in these areas is essential to achieve our national economic, social, and political goals. Steps are being taken by the National Science Foundation to make its structure better able to deal with engineering and applied research and to provide greater mutual reinforcement between applied and basic research.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Slaughter, J B -- New York, N.Y. -- Science. 1981 Mar 13;211(4487):1131-6.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/7466384" target="_blank"〉PubMed〈/a〉
    Keywords: Cell Biology ; Chemical Phenomena ; Chemistry ; *Forecasting ; Geological Phenomena ; Geology ; *Government Agencies ; Molecular Biology ; Neurochemistry ; Physical Phenomena ; Physics ; Research Support as Topic ; United States
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  • 28
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    New chemistry of an old molecule: cis-[Pt(NH3)2Cl2] (1982)
    American Association for the Advancement of Science (AAAS)
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    Publication Date: 1982-12-10
    Description: The discovery that cis-diamminedichloroplatinum(II) (cis-DDP) has clinically useful antitumor properties and can form platinum blues spawned an extensive investigation of its chemistry in water. Several new molecules have been synthesized, some rather old ones have been characterized for the first time, and clues have begun to emerge about the chemical interaction of cis-DDP with its likely biological target, DNA.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Lippard, S J -- New York, N.Y. -- Science. 1982 Dec 10;218(4577):1075-82.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/6890712" target="_blank"〉PubMed〈/a〉
    Keywords: Chemical Phenomena ; Chemistry ; *Cisplatin ; *Dna ; Hydrolysis ; Pigments, Biological
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  • 29
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    The chemistry of vision (1982)
    American Association for the Advancement of Science (AAAS)
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    Publication Date: 1982-12-03
    Description: The visual response is initiated by light reception and transduction into chemical and electrical energy in the outer-segment membranes of rod and cone cells. Recent research on the molecular events controlled by light has clarified the roles of some of the rod outer-segment biomolecules. These developments and the current unresolved questions are described.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉O'Brien, D F -- New York, N.Y. -- Science. 1982 Dec 3;218(4576):961-6.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/6291153" target="_blank"〉PubMed〈/a〉
    Keywords: Animals ; Blood Proteins/metabolism ; Calcium/metabolism ; Chemical Phenomena ; Chemistry ; Enzyme Activation ; Enzymes/metabolism ; GTP-Binding Proteins ; Light ; Membranes/metabolism ; Models, Biological ; Phosphoric Diester Hydrolases/biosynthesis ; Photoreceptor Cells/*metabolism ; Receptors, Cell Surface/metabolism ; Rhodopsin/metabolism ; Rod Cell Outer Segment/*metabolism ; Vision, Ocular/*physiology
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  • 30
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    Antiviral agents (1983)
    American Association for the Advancement of Science (AAAS)
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    Publication Date: 1983-06-10
    Description: 〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Krenitsky, T A -- Beauchamp, L -- New York, N.Y. -- Science. 1983 Jun 10;220(4602):1106.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/6857236" target="_blank"〉PubMed〈/a〉
    Keywords: Acyclovir/metabolism ; *Antiviral Agents/metabolism ; Chemical Phenomena ; Chemistry ; Humans ; Vidarabine/metabolism
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  • 31
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    Metastable species of hemoglobin: room temperature transients and cryogenically trapped intermediates (1983)
    American Association for the Advancement of Science (AAAS)
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    Publication Date: 1983-05-06
    Description: Resonance Raman spectra of photolyzed carbonmonoxyhemoglobin obtained with 10-nanosecond pulses are compared with the spectra of photolyzed carbonmonoxyhemoglobin stabilized at 80 K. In comparing the deoxy with the photodissociated species, the changes in the Raman spectra are the same for these two experimental regimes. These results show that at ambient and cryogenic temperatures the heme pocket in liganded hemoglobin is significantly different from that of deoxyhemoglobin. It is concluded that measurements of the properties of intermediate species from photodissociated hemoglobin stabilized at low temperatures can be used to probe the short-lived metastable forms of hemoglobin present after photodissociation under biologically relevant solution conditions.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Ondrias, M R -- Friedman, J M -- Rousseau, D L -- New York, N.Y. -- Science. 1983 May 6;220(4597):615-7.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/6836305" target="_blank"〉PubMed〈/a〉
    Keywords: Carboxyhemoglobin ; Chemical Phenomena ; Chemistry ; Freezing ; *Hemoglobins ; Humans ; Ligands ; Spectrum Analysis, Raman ; Temperature
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  • 32
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    Irreversible ligands with high selectivity toward delta and mu opiate receptors (1983)
    American Association for the Advancement of Science (AAAS)
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    Publication Date: 1983-04-15
    Description: Alkylating agents that display strong selectivity for opiate receptor types delta or mu were prepared by appropriate modification of the structures of the strong analgesics fentanyl, etonitazene, and endoethenotetrahydrooripavine. The availability of these substances should facilitate studies of the structural basis of receptor specificity and of the physiologic roles of these receptors.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Rice, K C -- Jacobson, A E -- Burke, T R Jr -- Bajwa, B S -- Streaty, R A -- Klee, W A -- New York, N.Y. -- Science. 1983 Apr 15;220(4594):314-6.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/6132444" target="_blank"〉PubMed〈/a〉
    Keywords: Alkylation ; Animals ; Benzimidazoles/analogs & derivatives/metabolism ; Brain/physiology ; Cells, Cultured ; Chemical Phenomena ; Chemistry ; Enkephalin, Methionine/analogs & derivatives/metabolism ; Fentanyl/analogs & derivatives/metabolism ; *Isothiocyanates ; Ligands ; Rats ; Receptors, Opioid/*metabolism/physiology ; Thebaine/analogs & derivatives/pharmacology
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  • 33
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    Trace chemistries of fire: a source of chlorinated dioxins (1980)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1980-10-01
    Description: 〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Bumb, R R -- Crummett, W B -- Cutie, S S -- Gledhill, J R -- Hummel, R H -- Kagel, R O -- Lamparski, L L -- Luoma, E V -- Miller, D L -- Nestrick, T J -- Shadoff, L A -- Stehl, R H -- Woods, J S -- New York, N.Y. -- Science. 1980 Oct;210(4468):385-90.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/6159682" target="_blank"〉PubMed〈/a〉
    Keywords: Air Pollutants/analysis ; Chemical Phenomena ; Chemistry ; Chromatography, High Pressure Liquid ; *Dioxins/analysis ; *Fires ; Power Plants ; Smoke/analysis ; Soil Pollutants/analysis ; Tetrachlorodibenzodioxin/analysis ; Vehicle Emissions/analysis ; Water Pollutants, Chemical/analysis
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
    Published by American Association for the Advancement of Science (AAAS)
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    Synthetic competitive antagonists of corticotropin-releasing factor: effect on ACTH secretion in the rat (1984)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1984-05-25
    Description: Polypeptide analogs of the known members of the corticotropin-releasing factor (CRF) family were synthesized and tested in vitro and in vivo for enhanced potency or competitive antagonism. Predictive methods and physicochemical measurements had suggested an internal secondary alpha-helical conformation spanning about 25 residues for at least three members of the CRF family. Maximization of alpha-helix-forming potential by amino acid substitutions from the native known sequences (rat/human and ovine CRF, sauvagine, and carp and sucker urotensin 1) led to the synthesis of an analog that was found to be more than twice as potent as either of the parent peptides in vitro. In contrast, certain amino-terminally shortened fragments, such as alpha-helical CRF or ovine CRF residues 8 to 41, 9 to 41, and 10 to 41, were found to be competitive inhibitors in vitro. Selected antagonists were examined and also found to be active in vivo.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Rivier, J -- Rivier, C -- Vale, W -- AA03504/AA/NIAAA NIH HHS/ -- AM20917/AM/NIADDK NIH HHS/ -- AM26741/AM/NIADDK NIH HHS/ -- etc. -- New York, N.Y. -- Science. 1984 May 25;224(4651):889-91.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/6326264" target="_blank"〉PubMed〈/a〉
    Keywords: Adrenocorticotropic Hormone/secretion ; Animals ; Binding, Competitive ; Chemical Phenomena ; Chemistry ; Corticotropin-Releasing Hormone/*antagonists & inhibitors ; Rats
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
    Published by American Association for the Advancement of Science (AAAS)
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    Computer processed LANDSAT data (1982)
    In:  CASI
    Details
    Publication Date: 2009-11-16
    Description: Background information and exercises are provided to: (1) establish or expand understanding of the concepts, methods, and terminology of computer processing of image producing data; (2) develop insight into the advantages of computer based image processing compared with the photointerpretation approach for processing, classifying, interpreting, and applying remote sensing data; (3) foster a broad perspective on the principal of the main techniques for image enhancement, pattern recognition, and thematic classification; (4) appreciate the pros and cons of batch and interactive modes of image analysis; (5) examine and evaluate some specific computer generated products for subscenes in Pennsylvania and New Jersey; and (6) interrelate these particular examples of output with more theoretical explanations of computer processing strategies and procedures.
    Keywords: EARTH RESOURCES AND REMOTE SENSING
    Type: The LANDSAT Tutorial Workbook; p 145-232
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    Radar-visible wind streaks in the Altiplano of Bolivia (1984)
    In:  CASI
    Details
    Publication Date: 2006-04-06
    Description: Isolated knobs that are erosional remnants of central volcanoes or of folded rocks occur in several areas of the Altiplano are visible on both optical and images. The optically visible streaks occur in the immediate lee of the knobs, whereas the radar visible streaks occur in the zone downwind between the knobs. Aerial reconnaissance and field studies showed that the optically visible streaks consist of a series of small ( 100 m wide) barchan and barchanoid dunes, intradune sand sheets, and sand hummocks (large shrub coppice dunes) up to 15 m across and 5 m high. On LANDSAT images these features are poorly resolved but combine to form a bright streak. On the radar image, this area also appears brighter than the zone of the radar dark streak; evidently, the dunes and hummocks serve as radar reflectors. The radar dark streak consists of a relatively flat, smooth sand sheet which lacks organized aerolian bedforms, other than occasional ripples. Wind velocity profiles show a greater U value in the optically bright streak zone than in the radar dark streak.
    Keywords: EARTH RESOURCES AND REMOTE SENSING
    Type: NASA. Washington Rept. of Planetary Geology Program, 1983; p 271-272
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    The erosion of streamlined islands, longitudinal grooves and scour marks: Implications to the origin of the Martian outflow channels (1984)
    In:  CASI
    Details
    Publication Date: 2006-04-06
    Description: The diversity of proposed origins for large Martian outflow channels results from the differing interpretations given to the landforms associated with the outflow channels. In an attempt to help limit the possible mechanisms of channel erosion, detailed studies of three of the channel features were done; the streamlined islands, longitudinal grooves and scour marks. This examination involved a comparison of the martian streamlined islands with various streamlined landforms on Earth including those found in the Channel Scabland in large rivers, glacial drumlins, and desert yardangs. The comparisons included statistical analyses of the landform lengths versus widths and positions of maximum width, and an examination of the degree of shape agreement with the geometric lemniscate which was in turn demonstrated to correspond closely with true airfoil shapes. The analyses showed that the shapes of the martian islands correspond closely to the streamlined islands in rivers and the Channel Scabland land. Drumlins show a much smaller correlation. Erosional rock islands formed by glaciers are very much different in shape.
    Keywords: EARTH RESOURCES AND REMOTE SENSING
    Type: NASA. Washington Rept. of Planetary Geol. Programs; p 200-202
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    Space debris impact experiment (S0001) (1984)
    In:  CASI
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    Publication Date: 2006-02-14
    Description: The specific objectives of this experiment are to establish the population and size distribution of meteoroids in the mass range from 10 to the minus 10 power to 10 to the minus 4 power G, to establish the current population of man-made debris in the same mass range, and to obtain data on the physical properties (composition and density) of meteoroids.
    Keywords: ASTROPHYSICS
    Type: Long Duration Exposure Facility (LDEF); p 136-137
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    Interplanetary dust experiment (A0201) (1984)
    In:  CASI
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    Publication Date: 2006-02-14
    Description: The objective of this experiment is to study interplanetary dust, variously referred to as cosmic dust, cometary dust, zodiacial dust, or meteoric dust particles. Specific objectives are to obtain information regarding particle mass and velocity, and to undertake correlative analyses with other experiments, both on LDEF or near the time of the LDEF flight.
    Keywords: ASTROPHYSICS
    Type: Long Duration Exposure Facility (LDEF); p 134-135
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  • 40
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    Attempt at dust debris collection with stacked detectors (A0138-2) (1984)
    In:  CASI
    Details
    Publication Date: 2006-02-14
    Description: The primary objective of this experiment is to investigate the feasibility of future missions of multilayer thin-film detectors acting as energy sorter to collect micrometeoroids, if not in their original shape, at least as fragments suitable for chemical analysis. It is expected that this kind of particle collector will help in solving one of the most puzzling topics in cosmic-dust studies: the mineralogical and chemical composition of the particles. This is a matter of great interest in the study of the origin and evolution of the solar system.
    Keywords: ASTROPHYSICS
    Type: NASA. Langley Research Center Long Duration Exposure Facility (LDEF); p 124-126
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  • 41
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    Appendix C. LANDSAT: A worldwide perspective (1982)
    In:  CASI
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    Publication Date: 2006-04-16
    Description: Images characteristics of geographic regions other than the northeastern part of the United States are presented for interpretation. Pre- and post-eruption imagery of Mt. St. Helens volcano serves to demonstrate the advantages of thermal infrared sensing, and the potential for developing a timely, decision oriented thematic map to be used in solving drought-related problems in Upper Volta is examined to show the applicability of satellite remote sensing in all geographic areas.
    Keywords: EARTH RESOURCES AND REMOTE SENSING
    Type: The LANDSAT Tutorial Workbook; p 455-475
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  • 42
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    Impact of Mount St. Helens eruption on hydrology and water quality (1982)
    In:  CASI
    Details
    Publication Date: 2006-04-12
    Description: The 1980 eruptions of Mount St. Helens in southeast Washington resulted in a pronounced effect on the surface and ground water resources of the state. In response to the volcanic activity, the U.S. Geological Survey intensified statewide surface and ground water sampling programs to determine the nature and magnitude of the volcanic-induced variations. Streams to the east of Mount St. Helens received the major ash fallout. Chemical effects were best noted in smaller streams sampled 60 to 70 miles northeast of Mount St. Helens. The chemical variations observed were pronounced but short lived. Sulfate and chloride increases in anionic composition were prevalent immediately following the eruption; however, the original bicarbonate predominance was again attained within several days. Suspended iron and aluminum concentrations were similarly elevated during the period of greatest ash deposition (highest turbidity); however, the dissolved concentrations remained relatively constant. Depressions of pH were minor and short lived. Streams draining to the south, tributaries to the Columbia river, showed little observable changes in water chemistry. Streams draining to the west (Toutle river and its tributaries) were compositionally affected by the various volcanic activities. Chloride and sulfate anion percentage exceeded the bicarbonate percentage up to one month following the eruption period. Streams and lakes sampled in the immediate vicinity of Mount St. Helens, in addition to trace metals, contained organic compounds derived from decomposing wood buried in the debris deposits. This organic material may constitute a significant source of organic compounds to surface and ground water for some time to come.
    Keywords: EARTH RESOURCES AND REMOTE SENSING
    Type: NASA. Langley Research Center Atmospheric Effects and Potential Climatic Impact of the 1980 Eruptions of Mt. St. Helens; p 43-46
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    Some closing thoughts: Practical payoffs from satellite systems (1982)
    In:  CASI
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    Publication Date: 2006-04-16
    Description: The benefits-to-cost ratio of satellite remote sensing, both as a substitute for conventional methods of monitoring and assessing resources, and as a supplement to these methods is examined using a model which analyzes the cost of aerial photography versus satellite scanner for producing and interpreting an image of the Earth's surface sized to LANDSAT dimensions. Examples of cost savings are tabulated for ground surveys, aerial photos, and LANDSAT. Possible additional benefits from LANDSAT D are assessed. The way in which satellites fit into more comprehensive models for resources management is discussed. It is shown that remote sensing is but one essential component in a complex system that aggregates technical. Socioeconomics, political, cultural, and other factors in the human decision process.
    Keywords: EARTH RESOURCES AND REMOTE SENSING
    Type: The LANDSAT Tutorial Workbook; p 389-407
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    Appendix B: Principles of computer processing of LANDSAT data (1982)
    In:  CASI
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    Publication Date: 2006-04-16
    Description: Computer processing facilitates extraction of information from every pixel by executing a variety of functional operations, called processed algorithms, in general or specialized routines. The best results are obtained when data from more than one multispectral band are used together. Multivariate tatistical analysis, computer tape characteristics, processing modes, and a choice of systems (batch or interactive) are discussed. The major operations in computer processing elaborated include: preprocessing, enhancement, effects of rationing, and classification. Techniques for multisource data correlation are considered with emphasis on geobased systems.
    Keywords: EARTH RESOURCES AND REMOTE SENSING
    Type: The LANDSAT Tutorial Workbook; p 421-453
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  • 45
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    Near surface observations (1982)
    In:  CASI
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    Publication Date: 2006-04-16
    Description: Learning objectives include: (1) developing an understanding of the implications of the term "near surface observations"; (2) associating the appearance of large ground features as seen in satellite imagery with their appearance as seen from the ground; (3) grasping criteria and procedures for selecting training sites on the ground for use in supervised classification; (4) running through an example of training site selection; (5) becoming familiar with several methods of accuracy assessment; (6) becoming aware of the approach and value of making supporting measurements of the spectral and physical properties of materials on the ground and from aircraft; (7) taking note of the different types of instruments used in making specific ground measurements; and (8) appreciating the rationale underlying laboratory and field studies on or near the Earth's surface for the purpose of developing new sensor systems.
    Keywords: EARTH RESOURCES AND REMOTE SENSING
    Type: The LANDSAT Tutorial Workbook; p 233-276
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  • 46
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    Photointerpretation of LANDSAT images (1982)
    In:  CASI
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    Publication Date: 2006-04-16
    Description: Learning objectives include: (1) developing a facility for applying conventional techniques of photointerpretation to small scale (satellite) imager; (2) promoting the ability to locate, identify, and interpret small natural and man made surface features in a LANDSAT image; (3) using supporting imagery, such as aerial and space photography, to conduct specific applications analyses; (4) learning to apply change detection techniques to recognize and explain transient and temporal events in individual or seasonal imagery; (5) producing photointerpretation maps that define major surface units, themes, or classes; (6) classifying or analyzing a scene for specific discipline applications in geology, agriculture, forestry, hyrology, coastal wetlands, and environmental pollution; and (7) evaluating both advantages and shortcomings in relying on the photointerpretive approach (rather than computer based analytical approach) for extracting information from LANDSAT data.
    Keywords: EARTH RESOURCES AND REMOTE SENSING
    Type: The LANDSAT Tutorial Workbook; p 101-143
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  • 47
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    Some spectral and spatial characteristics of LANDSAT data (1982)
    In:  CASI
    Details
    Publication Date: 2006-04-16
    Description: Activities are provided for: (1) developing insight into the way in which the LANDSAT MSS produces multispectral data; (2) promoting understanding of what a "pixel" means in a LANDSAT image and the implications of the term "mixed pixel"; (3) explaining the concept of spectral signatures; (4) deriving a simple signature for a class or feature by analysis: of the four band images; (5) understanding the production of false color composites; (6) appreciating the use of color additive techniques; (7) preparing Diazo images; and (8) making quick visual identifications of major land cover types by their characteristic gray tones or colors in LANDSAT images.
    Keywords: EARTH RESOURCES AND REMOTE SENSING
    Type: The LANDSAT Tutorial Workbook; p 81-99
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    Familiarization with LANDSAT imagery (1982)
    In:  CASI
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    Publication Date: 2006-04-16
    Description: Learning objectives of the activities provided include: (1) reading the annotation of a LANDSAT image; (2) becoming acquainted with the characteristics of 1:1,000,000 scale transparencies and prints of MSS images; (3) noting the general information visible in LANDSAT photo products; (4) observing changes of appearance of any ground feature or class in the black and white images made from the four MSS bands and the characteristic color of each class in color composites; (5) determining the degree to which a LANDSAT image meets map accuracy standards and can be fitted to map projections; (6) assessing the effects of LANDSAT enlargements and scale changes and of the limitations of satellite resolution relative to aerial photos; (7) observing the influence of time of acquisition (season) on a scene; (8) getting a feel for image quality as dependent on processing and photoreproduction; (9) appreciating the characteristics of the RBV and thermal band imagery obtained from LANDSAT-3; and (10) becoming familiar with certain attributes of adjacent LANDSAT images which permit them to be joined in mosaics and to be viewed in stereo.
    Keywords: EARTH RESOURCES AND REMOTE SENSING
    Type: The LANDSAT Tutorial Workbook; p 39-80
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    Appendix A: The LANDSAT system (1982)
    In:  CASI
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    Publication Date: 2006-04-16
    Description: The primary LANDSAT mission and the system requirements are summarized and pertinent parameters of the spacecraft, its orbit, and payload are tabulated. The history acquisition to entry into the archives for storage and product generation and dissemination is recounted. The LANDSAT D data handling plan is discussed showing requirements for both the MSS CCT and the thematic mapper CCT.
    Keywords: EARTH RESOURCES AND REMOTE SENSING
    Type: The LANDSAT Tutorial Workbook; p 409-419
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  • 50
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    Some fundamental concepts in remote sensing (1982)
    In:  CASI
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    Publication Date: 2006-04-16
    Description: The term remote sensing is defined as well as ideas such as class, pattern, feature, pattern recognition, feature extraction, and theme. The electromagnetic spectrum is examined especially those wavelength regions available to remote sensing. Relevant energy and wave propagation laws are discussed and the characteristics of emitted and reflected radiation and their detection are investigated. The identification of classes by their spectral signatures, the multispectral approach, and the principal types of sensors and platforms used in remote sensing are also considered.
    Keywords: EARTH RESOURCES AND REMOTE SENSING
    Type: The LANDSAT Tutorial Workbook; p 9-38
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    Microwave remote sensing experiment (1981)
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    Publication Date: 2006-06-04
    Description: Operation of the microwave instrument as a two frequency scatterometer, a synthetic aperture radar, and a passive microwave radiometer is planned. Operation of the instrument in each of its three modes is discussed and the antenna system described.
    Keywords: EARTH RESOURCES AND REMOTE SENSING
    Type: NASA. Marshall Space Flight Center Spacelab Mission 1 Expt. Descriptions; 3 p
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    Kinetic theory in astrophysics and cosmology (1982)
    In:  CASI
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    Publication Date: 2006-02-14
    Description: Results associated with exact solution of the Einstein-Boltzmann and Einstein-Maxwell-Boltzmann equations are presented. The generalization of Ehler's killing vector approach for the distribution function to charged particles is considered.
    Keywords: ASTROPHYSICS
    Type: Alabama Univ. in Huntsville The 1981 NASA(ASEE Summer Fac. Fellowship Program; 21 p
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    Multiprocess evolution of landforms in the Kharga Region, Egypt: Applications to Mars (1984)
    In:  CASI
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    Publication Date: 2006-04-06
    Description: In order to understand better the polygenetic evolution of landforms on the martian surface, field studies were conducted in and around the Kharga Depression, Egypt. The Kharga region, on the eastern edge of Egypt's Western Desert, was subject to erosion under mostly hyperarid climatic conditions, punctuated by brief pluvial episodes of lesser aridity, since early Pleistocene time. The region contains numerous landforms analogous to features on the martian surface: yardangs carved in layered surficial deposits and in bedrock, invasive dune trains, wind-modified channels and interfluves, and depressions bounded by steep scarps. Like many of the topographic depresions on Mars, the Kharga Depression was invaded by crescentic dunes. In Egypt, stratigraphic relations between dunes, yardangs, mass-wasting debris, and wind-eroded flash-flood deposits record shifts in the relative effectiveness of wind, water, and mass-wasting processes as a function of climate change.
    Keywords: EARTH RESOURCES AND REMOTE SENSING
    Type: NASA. Washington Rept. of Planetary Geology Program, 1983; p 225-227
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    A comparison of stratified versus regression estimators (1981)
    In:  CASI
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    Publication Date: 2006-02-14
    Description: LANDSAT data acquired over an agricultural area along with ground enumeration of the same area are used to obtain crop acreage estimates which are better (as measured in terms of bias and variance) than can be obtained from either data source alone. Two basic approaches considered within the AgRISTARS program are a stratified crop acreage estimator and a regression estimator. A statement of the problem was mathematically formulated and some theorems were proved which relate to the variance of the two estimators. For a particular set of data, the regression and stratified estimators are compared in terms of certain easily computed parameters.
    Keywords: EARTH RESOURCES AND REMOTE SENSING
    Type: Houston Univ. The 1981 NASA ASEE Summer Fac. Fellowship Program, Vol. 2; 17 p
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    Experiments examining the shapes of isolated bars in comparison with those occurring in braided rivers (1984)
    In:  CASI
    Details
    Publication Date: 2006-04-06
    Description: Sand bars and islands within braided rivers have characteristic rhomboid or diamond shapes, often becoming very complex in form as the density of islands increases. Similar forms are observed in the martian outflow channels where the islands occur in groups. This contrasts with the more isolated martian islands which have airfoil shapes, as do isolated streamlined islands in rivers and in the Channeled Scabland. These observations indicate that the bar and island forms are controlled by the density of the islands, with increasing island interaction and flow modification as the density increases. As a continuation of previous flume experiments on the shapes of isolated islands, a new series of experiments investigate the modifications produced by a progressive increase in island density, finally leading to a true braided system.
    Keywords: EARTH RESOURCES AND REMOTE SENSING
    Type: NASA. Washington Rept. of Planetary Geol. Programs; p 198-199
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    Interstellar-gas experiment (A0038) (1984)
    In:  CASI
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    Publication Date: 2006-02-14
    Description: The objectives of this experiment are to collect and isotopically analyze interstellar gas atoms around the orbit of the Earth for the purpose of obtaining new data relevant to understanding nucleosynthesis, and to study the dynamics of the interstellar wind inside the heliosphere and the isotopic composition of the interstellar medium outside the heliosphere. The experiment hardware will act as a set of simple cameras with high-purity copper-beryllium collecting foils serving as the film. The experiment housing will mount and thermally control the foils, establish the viewing angles and viewing direction, provide baffling to reject ambient neutral particles, provide a voltage grid to reject ionospheric charged particles, sequence collecting foils, control exposure times, and protect the foils from contamination during the deployment and retrieval of the LDEF. After being returned to Earth, the entrapped atoms can be analyzed by mass spectroscopy to determine the relative abundance of the different isotopes of helium and neon. An attempt will also be made to detect argon.
    Keywords: ASTROPHYSICS
    Type: NASA. Langley Research Center Long Duration Exposure Facility (LDEF); p 98-100
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    Other remote sensing systems: Retrospect and outlook (1982)
    In:  CASI
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    Publication Date: 2006-04-16
    Description: The history of remote sensing is reviewed and the scope and versatility of the several remote sensing systems already in orbit are discussed, especially those with sensors operating in other EM spectral modes. The multisensor approach is examined by interrelating LANDSAT observations with data from other satellite systems. The basic principles and practices underlying the use of thermal infrared and radar sensors are explored and the types of observations and interpretations emanating from the Nimbus, Heat Capacity Mapping Mission, and SEASAT programs are examined. Approved or proposed Earth resources oriented missions for the 1980's previewed include LANDSAT D, Stereosat, Gravsat, the French satellite SPOT-1, and multimission modular spacecraft launched from space shuttle. The pushbroom imager, the linear array pushbroom radiometer, the multispectral linear array, and the operational LANDSAT observing system, to be designed the LANDSAT-E series are also envisioned for this decade.
    Keywords: EARTH RESOURCES AND REMOTE SENSING
    Type: The LANDSAT Tutorial Workbook; p 327-387
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    A case study in the practical use of LANDSAT data (1982)
    In:  CASI
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    Publication Date: 2006-04-16
    Description: The use of computer aided classification of LANDSAT data in developing water quality plans for New Jersey watersheds is used to exemplify how a state natural resource management program benefits from satellite imagery. The transition of a research and development system into an operational remote sensing system to help decision makers is demonstrated. Nontechnial issues that can assist (or hinder) an agency in adopting a new technology are examined. The progress of LANDSAT use by state government from the earliest stage of curiosity through to incorporation in actual state planning methods is charted. Potential applications of LANDSAT data to real information needs and solutions to management problems are examined. The problems and mistakes that occurred in using LANDSAT data in the past are discussed as well as the ways by which these problems were overcome.
    Keywords: EARTH RESOURCES AND REMOTE SENSING
    Type: The LANDSAT Tutorial Workbook; p 309-326
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    Geographic information systems (1982)
    In:  CASI
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    Publication Date: 2006-04-16
    Description: Information and activities are provided to: (1) enhance the ability to distinguish between a Geographic Information System (GIS) and a data management system; (2) develop understanding of spatial data handling by conventional methods versus the automated approach; (3) promote awareness of GIS design and capabilities; (4) foster understanding of the concepts and problems of data base development and management; (5) facilitate recognition of how a computerized GIS can model conditions in the present "real world" to project conditions in the future; and (6) appreciate the utility of integrating LANDSAT and other remotely sensed data into the GIS.
    Keywords: EARTH RESOURCES AND REMOTE SENSING
    Type: The LANDSAT Tutorial Workbook; p 277-308
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    Characteristics of the SIR-A system and images (1984)
    In:  Other Sources
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    Publication Date: 2011-08-19
    Description: Sample images obtained with the Shuttle Imaging Radar A (SIR-A) are presented, along with design and performance features of the SIR-A, Seasat and Landsat images of the same scenes for comparison purposes. The SIR-A functions at the L-band 25 cm at a frequency of 1278 GHz with a spectral bandwidth of 6 MHz. The images were taken at an angle of 47 deg and furnished a resolution of 40 m from an altitude of 259 km. The images covered a ground swath 50 km wide. The images are provided to assist in the development of effective techniques for interpreting radar imagery. The SIR-A instrument is a precursor of another imaging device which will be flown around Venus. The images provided include sections of France, Sardinia and Algeria.
    Keywords: EARTH RESOURCES AND REMOTE SENSING
    Type: Photo Interpretation (ISSN 0031-8523); 23; 4-17
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    Analysis of Landsat-4 Thematic Mapper data for classification of forest stands in Baldwin County, Alabama (1984)
    In:  Other Sources
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    Publication Date: 2011-08-18
    Description: A computer-implemented classification has been derived from Landsat-4 Thematic Mapper data acquired over Baldwin County, Alabama on January 15, 1983. One set of spectral signatures was developed from the data by utilizing a 3x3 pixel sliding window approach. An analysis of the classification produced from this technique identified forested areas. Additional information regarding only the forested areas. Additional information regarding only the forested areas was extracted by employing a pixel-by-pixel signature development program which derived spectral statistics only for pixels within the forested land covers. The spectral statistics from both approaches were integrated and the data classified. This classification was evaluated by comparing the spectral classes produced from the data against corresponding ground verification polygons. This iterative data analysis technique resulted in an overall classification accuracy of 88.4 percent correct for slash pine, young pine, loblolly pine, natural pine, and mixed hardwood-pine. An accuracy assessment matrix has been produced for the classification.
    Keywords: EARTH RESOURCES AND REMOTE SENSING
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    Satellite land remote sensing advancements for the eighties; Proceedings of the Eighth Pecora Symposium, Sioux Falls, SD, October 4-7, 1983 (1984)
    In:  Other Sources
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    Publication Date: 2011-08-18
    Description: Among the topics discussed are NASA's land remote sensing plans for the 1980s, the evolution of Landsat 4 and the performance of its sensors, the Landsat 4 thematic mapper image processing system radiometric and geometric characteristics, data quality, image data radiometric analysis and spectral/stratigraphic analysis, and thematic mapper agricultural, forest resource and geological applications. Also covered are geologic applications of side-looking airborne radar, digital image processing, the large format camera, the RADARSAT program, the SPOT 1 system's program status, distribution plans, and simulation program, Space Shuttle multispectral linear array studies of the optical and biological properties of terrestrial land cover, orbital surveys of solar-stimulated luminescence, the Space Shuttle imaging radar research facility, and Space Shuttle-based polar ice sounding altimetry.
    Keywords: EARTH RESOURCES AND REMOTE SENSING
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    High spatial resolution IR observations of young stellar objects - A possible disk surrounding HL Tauri (1984)
    In:  Other Sources
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    Publication Date: 2011-08-18
    Description: High spatial resolution images of the T Tauri star HL Tau were obtained at 1.6 microns and 2.2 microns. The original images as well as maximum entropy image reconstructions reveal a circumstellar envelope structure, similar at both wavelenghts, and extended along P.A. = 112 deg; the 10 percent width of the structure is 1.9 sec (300 AU at 160 pc). The extended structure is interpreted as light scattered toward earth by dust in a disk surrounding this young stellar object. Polarization measurements made at 2.2 microns support this hypothesis. The total solid particle mass is, at minimum, 5 x 10 to the -7th solar mass.
    Keywords: ASTROPHYSICS
    Type: Astrophysical Journal, Part 2 - Letters to the Editor (ISSN 0004-637X); 283; L57-L61
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  • 64
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    X-ray spectra of young supernova remnants (1983)
    In:  Other Sources
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    Publication Date: 2011-08-18
    Description: Einstein solid-state-spectrometer (SSS) spectra are presented for the Crab Nebula, Cas A, SN 1006, the Tycho SNR, and the Kepler SNR. The history of X-ray observations of SNRs is reviewed; the SSS instrument is briefly characterized; a reduction technique which accounts for all background sources in the 0.5-4.5-keV band is applied; and the physical models of SNRs constructed to reproduce the refined spectra are discussed. The limitations of the modeling methods and the need for further observations, especially of localized regions, are indicated.
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    Offshore oil in the Alaskan Arctic (1984)
    In:  Other Sources
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    Publication Date: 2011-08-18
    Description: Oil and gas deposits in the Alaskan Arctic are estimated to contain up to 40 percent of the remaining undiscovered crude oil and oil-equivalent natural gas within U.S. jurisdiction. Most (65 to 70 percent) of these estimated reserves are believed to occuur offshore beneath the shallow, ice-covered seas of the Alaskan continental shelf. Offshore recovery operations for such areas are far from routine, with the primary problems associated with the presence of ice. Some problems that must be resolved if efficient, cost-effective, environmentally safe, year-round offshore production is to be achieved include the accurate estimation of ice forces on offshore structures, the proper placement of pipelines beneath ice-produced gouges in the sea floor, and the cleanup of oil spills in pack ice areas.
    Keywords: EARTH RESOURCES AND REMOTE SENSING
    Type: Science (ISSN 0036-8075); 225; 371-378
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  • 66
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    Magnetic topology and the heating of extended chromospheres (1983)
    In:  Other Sources
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    Publication Date: 2011-08-18
    Description: New data indicate that red giants are surrounded by geometrically thick chromospheres of several stellar radii extent. Such chromospheres occur among stars which apparently lack coronae. Maintenance of this extended warm region may require non-compressional wave heating of a magnetic character, and this may provide a crucial clue to the mechanism of rapid mass loss from red giant stars.
    Keywords: ASTROPHYSICS
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  • 67
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    A sampling procedure to guide the collection of narrow-band, high-resolution spatially and spectrally representative reflectance data (1983)
    In:  Other Sources
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    Publication Date: 2011-08-18
    Description: A multistage sampling procedure using image processing, geographical information systems, and analytical photogrammetry is presented which can be used to guide the collection of representative, high-resolution spectra and discrete reflectance targets for future satellite sensors. The procedure is general and can be adapted to characterize areas as small as minor watersheds and as large as multistate regions. Beginning with a user-determined study area, successive reductions in size and spectral variation are performed using image analysis techniques on data from the Multispectral Scanner, orbital and simulated Thematic Mapper, low altitude photography synchronized with the simulator, and associated digital data. An integrated image-based geographical information system supports processing requirements.
    Keywords: EARTH RESOURCES AND REMOTE SENSING
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    Very slow classical Cepheids - Theoretical models with periods longer than 50 days (1984)
    In:  Other Sources
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    Publication Date: 2011-08-18
    Description: Systematics of the light curves of classical Cepheids with the longest known periods have been investigated with the help of full-amplitude models of pulsating stellar envelopes. For periods exceeding about 60 days, flat-topped light curves of the S Vul type are found to replace the smooth, asymmetric light curves characteristic of the slightly faster Cepheids. Predicted light and velocity amplitudes (although not the predicted radius amplitudes) agree well with observations. Variables with fluctuating light minima are observed to lie well off the mean period-luminosity relation, as are a few other (more stable?) variables with similarly long periods. The explanation for the long periods is probably low effective temperature rather than a low stellar mass. Because of the abnormal slowness of the classical Cepheids with periods longer than about 100 days, it is recommended that these variables not be used to calibrate the mean period-luminosity relation. Analogies between the slow classical Cepheids and the slow Population II Cepheids are drawn.
    Keywords: ASTROPHYSICS
    Type: Astrophysical Journal, Part 1 (ISSN 0004-637X); 281; 811-814
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  • 69
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    On the '3 kiloparsec arm' - Resonance excitation of linear and nonlinear waves by an oval distortion in the central region (1984)
    In:  Other Sources
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    Publication Date: 2011-08-18
    Description: The mechanism responsible for the massive rapidly expanding Galactic feature known as the 3-kpc arm (Rougoor and Oort, 1960) is investigated theoretically in the framework of a density-wave model of the Galaxy. The arm is attributed to outgoing waves excited at the outer Lindblad resonance (OLR) of a small rotating oval distortion near the Galactic center. Linear and nonlinear models are developed, and it is shown that a density crest at 3.5 kpc with expansion velocity 53 km/s can be generated by a distortion turning at 118 km/s kpc with a 10-percent perturbation of the main gravitational field at the OLR (located at 3 kpc). The wave character of the nonlinear solution is found to be the same as that of the linear solution and to give good agreement with the observations in terms of expansion velocity, size, shape, and mass; only the observed asymmetry of the arm is not reproduced.
    Keywords: ASTROPHYSICS
    Type: Astrophysical Journal, Part 1 (ISSN 0004-637X); 281; 600-613
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  • 70
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    Superclustering and the large-scale structure of the Universe (1984)
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    Publication Date: 2011-08-18
    Description: A complete redshift survey of nearby rich galactic clusters is analyzed in terms of a spatial correlation function, the growth of supercluster, the presence of superclusters around the Bootes void and the discovery of a 300 Mpc void. Abell's (1958) statistical sampling of rich clusters is used for the study. Attention is given to the dependence of the correlation function on the richness of the system, with finding that chances are greater of finding rich neighbors closer together than poor neighbors. Samples of redshifts of 4 or less correlate well with clusters of redshift 5 or more. The size of intergalactic voids is proportional to the surrounding galactic excesses. Finally, the superclusters exist on scales of about 100 Mpc/h, which is larger than expected.
    Keywords: ASTROPHYSICS
    Type: Advances in Space Research (ISSN 0273-1177); 3; 10-12
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    Ultraviolet spectral morphology of the O stars - The remarkable luminosity dependence of the Si IV stellar wind effect (1984)
    In:  Other Sources
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    Publication Date: 2011-08-18
    Description: An extensive survey of ultraviolet O type spectra, by means of high-resolution data from the International Ultraviolet Explorer archives, shows a strong correlation between both the photospheric and stellar wind features, and the optical spectral types. In particular, the stellar wind effect in the Si IV resonance doublet displays a strong luminosity dependence which has not been completely described before: there is no effect anywhere on the main sequence, but it develops gradually through the intermediate luminosity classes into a full P Cygni profile in the supergiants. This behavior is in sharp contrast to that of the C IV and N V, which have strong P Cygni profiles throughout most of the O type domain, including the main sequence. The Si IV effect simultaneously provides a sensitive classification criterion and poses an outstanding problem for detailed astrophysical interpretation. In addition, a new emission feature at 1574 A, possibly due to N III or to N IV forbidden line, is reported.
    Keywords: ASTROPHYSICS
    Type: Astrophysical Journal, Part 2 - Letters to the Editor (ISSN 0004-637X); 280; L27-L30
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    Do bipolar magnetic regions exist on the surfaces of early-type stars? (1984)
    In:  Other Sources
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    Publication Date: 2011-08-18
    Description: The observations of relatively narrow absorption components of the UV resonance lines in the spectra of early-type stars are reviewed, and some new observational data are presented for Rho Leo (B1 Ib). It is shown that the discrete components which are seen in the UV resonance lines of early-type stars are a result of ejection from local spots above the photospheres of hot stars. It is suggested that localized ejection is caused by magnetic flux lines associated with a bipolar magnetic region on the surface of the star.
    Keywords: ASTROPHYSICS
    Type: Astrophysical Journal, Part 1 (ISSN 0004-637X); 280; 712-728
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  • 73
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    Models of the hard X-ray spectrum of AM Herculis and implications for the accretion rate (1984)
    In:  Other Sources
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    Publication Date: 2011-08-18
    Description: Phenomenological fits to the hard X-ray spectrum of AM Hercules have failed to explain the high equivalent width (0.8 + or - 0.1 keV) of Fe K-alpha emission. The scattering and fluorescent line production in a cold or partially ionized accretion column of hard X-rays emitted at the base are investigated using the Monte Carlo method. It is shown that the Fe emission equivalent width observed in the spectrum of AM Her can be explained without resorting to an overabundance of Fe in the accreting material. For sufficient optical depth across the accretion column, equivalent widths of K-alpha emission even larger than the observed values can be obtained. The accretion rate and gravitational power can be deduced from the optical depth across the column, if the column size is known, and, together with the observed hard X-ray and polarized light luminosities, imply a lower limit for the luminosity in the UV to soft X-ray range, for which the observations give model-dependent values.
    Keywords: ASTROPHYSICS
    Type: Astrophysical Journal, Part 1 (ISSN 0004-637X); 280; 734-743
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    Disappearance and disintegration of comets (1984)
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    Publication Date: 2011-08-18
    Description: The present investigation has the objective to provide a summary of the existing evidence on the disappearance of comets and to draw conclusions regarding the physical processes involved in the disappearance. Information concerning the classification of evidence and the causes of apparent disappearance of comets is presented in a table. Attention is given to the dissipating comets, the headless sungrazing comet 1887 I, and the physical behavior of the dissipating comets and the related phenomena. It is found that all comets confined to the planetary region of the solar system decay on astronomically short time scales. However, only some of them appear to perish catastrophically. Some of the observed phenomena could be successfully interpreted. But little insight has been obtained into the character of the processes which the dissipating comets experience.
    Keywords: ASTROPHYSICS
    Type: Icarus (ISSN 0019-1035); 58; 81-100
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  • 75
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    X-ray spectral signatures of accreting black holes (1984)
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    Publication Date: 2011-08-18
    Description: The X-ray properties of the binary black hole candidates include distinctive bimodal spectral behavior where the X-ray spectra switch between being very soft (alpha greater than 3) and hard (alpha about 0.7). It is pointed out that this spectral transition occurs at about 1 percent L(edd) (for accretion onto a 10 solar masses black hole), and that this corresponds to the luminosity where an optically thick electron-positron pair plasma will form. Active galactic nuclei (AGN) are often considered to be accreting black holes. An X-ray spectral similarity between the above binary sources and both the Seyfert I and BL Lac classes of AGN is demonstrated. As many of these objects radiate most of their luminosity as X-rays, such a similarity may be expected if the underlying mechanisms are similar.
    Keywords: ASTROPHYSICS
    Type: Astronomy and Astrophysics (ISSN 0004-6361); 133; 2, Ap
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    Spectral analysis of magnetohydrodynamic fluctuations near interplanetary shocks (1984)
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    Publication Date: 2011-08-18
    Description: Preliminary results of an investigation of magnetic fluctuations seen upstream of two interplanetary shocks are presented. The spectral analysis includes calculation of the normalized reduced magnetic helicity spectrum, the normalized reduced cross-helicity spectrum, and the Alfven ratio as discussed by Matthaeus and Goldstein (1982). Minimum variance methods are used to compute wave polarization as a function of frequency. The Taylor 'frozen in flow' hypothesis is assumed to convert frequencies to wave vectors. Some of the basic properties of the waves, including the probable mode of propagation in association with both quasi-parallel forward and reverse shocks, are described. A comparison with previous results on the generation of waves at interplanetary and planetary shocks is presented.
    Keywords: ASTROPHYSICS
    Type: Journal of Geophysical Research (ISSN 0148-0227); 89; 3762-377
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  • 77
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    Calculations of radar backscattering coefficient of vegetation-covered soils (1984)
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    Publication Date: 2011-08-18
    Description: The present investigation has the objective to develop a simple 'user's' model for simulating the measured radar backscattering coefficients from vegetation-covered fields in conjunction with the data obtained by Jackson et al. (1980, 1982). The theoretical work reported by Fung and Eom (1981) provides the basis for the model. Certain modifications are related to a consideration of the effect of a vegetation canopy. The first part of the model is concerned with a description of scatter from rough bare soil, while the second part takes into account the effect of a vegetation cover. It is shown that the measured angular distribution of the backscattering coefficient of vegetation-covered fields can be satisfactory reproduced by using the developed model.
    Keywords: EARTH RESOURCES AND REMOTE SENSING
    Type: Remote Sensing of Environment (ISSN 0034-4257); 15; 119-133
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    Atmospheric effect on classification of finite fields (1984)
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    Publication Date: 2011-08-18
    Description: The atmospheric effect on the upward radiance of sunlight scattered from the earth-atmosphere system is strongly influenced by the contrasts between fields and their sizes. In this paper, the radiances above finite fields are computed to simulate radiances measured by a satellite. A simulation case including 11 agricultural fields and four natural fields (water, soil, savanah, and forest) is used to test the effect of field size, background reflectance, and optical thickness of the atmosphere on the classification accuracy. For a given atmospheric turbidity, the atmospheric effect on classification of surface features may be much stronger for nonuniform surfaces than for uniform surfaces. Therefore, the classification accuracy of agricultural fields and urban areas is dependent not only on the optical characteristics of the atmosphere, but also on the size of the surface elements to be classified and their contrasts. It is concluded that new atmospheric correction methods, which take into account the finite size of the fields, are needed.
    Keywords: EARTH RESOURCES AND REMOTE SENSING
    Type: Remote Sensing of Environment (ISSN 0034-4257); 15; 95-118
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    HEAO 3 observations of the Crab pulsar (1984)
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    Publication Date: 2011-08-18
    Description: The Crab pulsar (PSR 0531+21) is the only pulsar which has been observed throughout almost the entire electromagnetic spectrum from 0.5 keV to over 2000 GeV. In general, the emission from the Crab nebula and its pulsar has been remarkably constant in time (except for the pulsations). However, several recent observations, especially of gamma-ray line emission, indicate possible time variations. The present investigation is concerned with the data obtained with the HEAO C-1 experiment. The data have been studied with the hope of finding information regarding a number of questions, taking into account the existence of line emission from the pulsar, the variation of the shape of the light curve with time, and the spectral variations as a function of pulsar phase. The spectrum of the total phase-averaged pulsed emission is found to be consistent with a single power-law spectrum from 50 keV to 10 MeV.
    Keywords: ASTROPHYSICS
    Type: Astrophysical Journal, Part 1 (ISSN 0004-637X); 278; 784-790
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    X-ray observations of X Persei (1984)
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    Publication Date: 2011-08-18
    Description: The HEAO 2 Einstein Observatory was used to confirm the identification of 4U 0352 + 30 with X Per. The HEAO 2 data were analyzed in order to determine an additional point in the pulse period history of the X-ray source and to search for short binary periods. In addition, a majority of the historical X-ray observations was reanalyzed and more refined values for the pulse period as a function of time were obtained. The period history possess significant scatter, but no evidence for a measurable long-term spin-up trend is found, and hence a lower limit to the spin-up time scale is set. This lower limit is consistent with the presence of a neutron star, but it does not rule out a degenerate dwarf. The period history was also searched for evidence of binary motion, and upper limits to a(x) sin i were obtained.
    Keywords: ASTROPHYSICS
    Type: Astrophysical Journal, Part 1 (ISSN 0004-637X); 278; 711-715
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    Variable ultraviolet emission in SY Muscae (1984)
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    Publication Date: 2011-08-18
    Description: The results of continued IUE monitoring of the symbiotic variable SY Muscae, following an earlier report of a radical enhancement in UV emission from the star, are reported. Over the course of one year, the prominent emission lines of N V, O V, C IV, and He II appear to be gradually decreasing in absolute intensity. This appears to coincide with a steady decline in electron density in the emission line forming region. The data are consistent with a sudden ejection event in which material expelled from the surface of a hot subdwarf has exposed the underlying UV continuum of the star. A number of strong emission lines that are photoexcited by the intense radiation field of the secondary also exhibit broad pedestal emission that suggests turbulent velocities of about 150-300 km/s in an expanding shell or possibly in an accretion disk.
    Keywords: ASTROPHYSICS
    Type: Royal Astronomical Society, Monthly Notices (ISSN 0035-8711); 207; 575-583
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    Radiometric calibration of Seasat SAR imagery (1983)
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    Publication Date: 2011-08-18
    Description: A goal of future synthetic aperture radar (SAR) system design is to yield the radiometrically accurate imagery necessary for use in classification problems. To accomplish this, a reliable calibration technique must be developed. Many such techniques have been proposed (e.g., Stiles and Holtzman, 1982); however, until now, none have been tested on spaceborne SAR digital data. In this paper, a method of significantly increasing the reproducibility of several independent Seasat SAR data sets of a test site using an automated correction procedure is described.
    Keywords: EARTH RESOURCES AND REMOTE SENSING
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    The influence of autocorrelation in signature extraction - An example from a geobotanical investigation of Cotter Basin, Montana (1984)
    In:  Other Sources
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    Publication Date: 2011-08-18
    Description: The presence of positive serial correlation (autocorrelation) in remotely sensed data results in an underestimate of the variance-covariance matrix when calculated using contiguous pixels. This underestimate produces an inflation in F statistics. For a set of Thematic Mapper Simulator data (TMS), used to test the ability to discriminate a known geobotanical anomaly from its background, the inflation in F statistics related to serial correlation is between 7 and 70 times. This means that significance tests of means of the spectal bands initially appear to suggest that the anomalous site is very different in spectral reflectance and emittance from its background sites. However, this difference often disappears and is always dramatically reduced when compared to frequency distributions of test statistics produced by the comparison of simulated training sets possessing equal means, but which are composed of autocorrelated observations.
    Keywords: EARTH RESOURCES AND REMOTE SENSING
    Type: International Journal of Remote Sensing (ISSN 0143-1161); 5; 315-332
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    Observational parameters for remote sensing in the next decade (1982)
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    Publication Date: 2011-08-18
    Description: The spectral and spatial requirements for remote sensing in the next decade are presented. The requirements presented were obtained through extensive literature research and discussions with leading members of the various remote sensing research communities. In the 0.35-2.5 micron region of the spectrum, numerous bands will be needed at bandwidths as narrow as 10-20 nanometers. There is also growing interest in the thermal infrared (8-14 microns). Spatial resolution (instantaneous field of view) of 5 to 10 meters will be of great benefit to many fields of remote sensing.
    Keywords: EARTH RESOURCES AND REMOTE SENSING
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    Objective assessment of Advanced Very High Resolution Radiometer data for land cover mapping (1984)
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    Publication Date: 2011-08-18
    Description: The validity of using data from the Advanced Very High Resolution Radiometer (AVHRR) of the satellites NOAA-6 and NOAA-7 for land cover mapping is assessed by making comparisons with much higher resolution LANDSAT multi-spectral scanner (MSS) data. Near synchronous data for both systems are analysed for test sites in the Imperial Valley, California, the Nile Delta, and southern Italy. The results strongly indicate that despite the very coarse resolution of the AVHRR data compared with conventional MSS data they are sufficiently strongly correlated to suggest that the former have significant potential for land cover mapping, especially at small scales and for large areas. Hence the outstanding benefits of AVHRR data, namely their high temporal frequency, relative cheapness and low data volumes for image processing, may readily be taken advantage of for such tasks.
    Keywords: EARTH RESOURCES AND REMOTE SENSING
    Type: International Journal of Remote Sensing (ISSN 0143-1161); 5; 497-504
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    The remarkable ultraviolet spectrum of the planetary nebula Abell 30 (1984)
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    Publication Date: 2011-08-18
    Description: Abell 30 has been identified as a planetary nebula in which the nucleus has experienced a final helium shell flash after ejection of the original, outer envelope. Around the central star of the nebula, four knots of material are observed. In view of the importance of the chemical composition of the ejected material for studies of advanced stages of stellar evolution, clarification of the physical conditions in the knots is vital. Data obtained of Abell 30 with the aid of the International Ultraviolet Explorer (IUE) satellite are discussed along with aspects of extinction, the He II flux, ionic abundances, the C II lambda 4267 line, questions regarding the existence of a carbon-rich core in the knot, the heating of the nebular gas, the central star, and heating by suprathermal particles from the stellar wind. The UV spectrum of the inner nebulosity of Abell 30 indicates that an extraordinary amount of energy is being deposited in the gas.
    Keywords: ASTROPHYSICS
    Type: Astrophysical Journal, Part 1 (ISSN 0004-637X); 277; 716-724
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    Thermal microwave emission from vegetated fields - A comparison between theory and experiment (1984)
    In:  Other Sources
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    Publication Date: 2011-08-18
    Description: The radiometric measurements over bare field and fields covered with grass, soybean, corn, and alfalfa were made with 1.4- and 5-GHz microwave radiometers during August-October 1978. The measured results are compared with radiative transfer theory treating the vegetated fields as a two-layer random medium. It is found that the presence of a vegetation cover generally gives a higher brightness temperature T sub B than that expected from a bare soil. The amount of this T sub B excess increases with increase in the vegetation biomass and in the frequency of the observed radiation. The results of radiative transfer calculations, which include a parameter characterizing ground surface roughness, generally match well with the experimental data.
    Keywords: EARTH RESOURCES AND REMOTE SENSING
    Type: IEEE Transactions on Geoscience and Remote Sensing (ISSN 0196-2892); GE-22; 143-150
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  • 88
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    A note on the oxygen gradient in NGC 628 (1983)
    In:  Other Sources
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    Publication Date: 2011-08-18
    Description: The Kitt Peak 2.1-m telescope and Intensified Image Dissector Scanner have been used to gather spectrophotometric data in the 3600-5200 A spectral region for five H II regions in the spiral galaxy NGC 628. The Pagel et al (1979) technique was then applied to determine the relative number abundances of O to H in each of the H II regions. An examination of the abundance values obtained as a function of the radial coordinate yields an O gradient of -0.05 + or - 0.03 dex/kpc.
    Keywords: ASTROPHYSICS
    Type: Astronomical Society of the Pacific, Publications (ISSN 0004-6280); 95; 986-988
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  • 89
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    Inversion of vegetation canopy reflectance models for estimating agronomic variables. II - Use of angle transforms and error analysis as illustrated by Suits' model (1984)
    In:  Other Sources
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    Publication Date: 2011-08-18
    Description: The technique for inverting a vegetation canopy reflectance model described earlier (Goel and Strebel, 1983) is investigated further. The novel concept of an 'angle transform' is introduced. This concept allows the formation of functions of reflectances at different view zenith and azimuth angles, which are either sensitive or insensitive to a certain agronomic parameter. A proper combination of these functions can allow determination of all the important agronomic and spectral parameters from measured canopy reflectance data. The technique is demonstrated using Suits' (1972) model for homogeneous canopies. It is shown that leaf area index, leaf reflectance and transmittance, and average leaf angle all can be determined from the canopy reflectance at a set of selected view zenith and azimuth angles. A sensitivity analysis of the calculated values to the errors in the data is also carried out. Guidelines are formulated for the number and types of observations required to obtain the values of a particular canopy variable to within a given degree of accuracy for a given level of error in the measurement of canopy reflectance.
    Keywords: EARTH RESOURCES AND REMOTE SENSING
    Type: Remote Sensing of Environment (ISSN 0034-4257); 14; 77-111
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  • 90
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    A study of extreme carbon stars. I - Silicon carbide emission features (1984)
    In:  Other Sources
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    Publication Date: 2011-08-18
    Description: 10-micron spectra of many extreme carbon stars reveal a prominent emission feature near 11 microns. This is compared with laboratory spectra of SiC grains. Two distinct types of features are found, perhaps indicative of different mechanisms of grain formation in different stars. Estimates are made of probable column densities and total masses of SiC in the circumstellar shells.
    Keywords: ASTROPHYSICS
    Type: Royal Astronomical Society, Monthly Notices (ISSN 0035-8711); 206; 137-147
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  • 91
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    Testing for a cosmological influence on local physics using atomic and gravitational clocks (1983)
    In:  Other Sources
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    Publication Date: 2011-08-18
    Description: The existence of a possible influence of the large-scale structure of the universe on local physics is discussed. A particular realization of such an influence is discussed in terms of the behavior in time of atomic and gravitational clocks. Two natural categories of metric theories embodying a cosmic infuence exist. The first category has geodesic equations of motion in atomic units, while the second category has geodesic equations of motion in gravitational units. Equations of motion for test bodies are derived for both categories of theories in the appropriate parametrized post-Newtonian limit and are applied to the Solar System. Ranging data to the Viking lander on Mars are of sufficient precision to reveal (1) if such a cosmological influence exists at the level of Hubble's constant, and (2) which category of theories is appropriate for a descripton of the phenomenon.
    Keywords: ASTROPHYSICS
    Type: Physical Review D - Particles and Fields, 3rd Series (ISSN 0556-2821); 28; 1822-182
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  • 92
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    MHD processes in the outer heliosphere (1984)
    In:  Other Sources
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    Publication Date: 2011-08-19
    Description: The magnetic field measurements from Voyager and the magnetohydrodynamic (MHD) processes in the outer heliosphere are reviewed. A bibliography of the experimental and theoretical work concerning magnetic fields and plasmas observed in the outer heliosphere is given. Emphasis in this review is on basic concepts and dynamical processes involving the magnetic field. The theory that serves to explain and unify the interplanetary magnetic field and plasma observations is magnetohydrodynamics. Basic physical processes and observations that relate directly to solutions of the MHD equations are emphasized, but obtaining solutions of this complex system of equations involves various assumptions and approximations. The spatial and temporal complexity of the outer heliosphere and some approaches for dealing with this complexity are discussed.
    Keywords: ASTROPHYSICS
    Type: Space Science Reviews (ISSN 0038-6308); 39; 255-316
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  • 93
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    Cosmogony as an extrapolation of magnetospheric research (1984)
    In:  Other Sources
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    Publication Date: 2011-08-19
    Description: A theory of the origin and evolution of the Solar System which considered electromagnetic forces and plasma effects is revised in light of information supplied by space research. In situ measurements in the magnetospheres and solar wind can be extrapolated outwards in space, to interstellar clouds, and backwards in time, to the formation of the solar system. The first extrapolation leads to a revision of cloud properties essential for the early phases in the formation of stars and solar nebulae. The latter extrapolation facilitates analysis of the cosmogonic processes by extrapolation of magnetospheric phenomena. Pioneer-Voyager observations of the Saturnian rings indicate that essential parts of their structure are fossils from cosmogonic times. By using detailed information from these space missions, it is possible to reconstruct events 4 to 5 billion years ago with an accuracy of a few percent.
    Keywords: ASTROPHYSICS
    Type: Space Science Reviews (ISSN 0038-6308); 39; 65-90
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  • 94
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    Mapping of glacial landforms from Seasat radar images (1984)
    In:  Other Sources
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    Publication Date: 2011-08-19
    Description: Glacial landforms in the drumlin drift belt of Ireland and the Alaska Range can be identified and mapped from Seasat synthetic-aperture radar (SAR) images. Drumlins cover 60 percent of the Ireland scene. The width/length ratio of individual drumlins can be measured on the SAR images, allowing regional differences in drumlin shape to be mapped. This cannot be done with corresponding Landsat multispectral scanner (MSS) images because of lower spatial resolution and because of shadowing effects that vary seasonally. The Alaska scene shows the extent and nature of morphological features such as medial and lateral moraines, stagnant ice, and fluted ground moraine in glaciated valleys. Perception of these features on corresponding Landsat MSS images is limited by seasonal diffrences in solar illumination. Because SAR is not affected by such differences or by cloud cover, it is particularly well suited for monitoring glacial movement. The disadvantage of distorted high-relief features on Seasat SAR images can be reduced in future SAR systems by modifying the radar illumination geometry.
    Keywords: EARTH RESOURCES AND REMOTE SENSING
    Type: Quaternary Research (ISSN 0033-5894); 22; 314-327
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  • 95
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    Abundances in galactic H II regions. III - G25.4-0.2, G45.5+0.06, M8, S159, and DR 22 (1984)
    In:  Other Sources
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    Publication Date: 2011-08-19
    Description: Measurements of the ARII (6.99 microns), ArIII (8.99 microns), NeI (12.81 microns), SIII (18.71 microns), and SIV (10.51 microns) lines are presented for five compact HII regions along with continuum spectroscopy. From these data and radio data, lower limits to the elemental abundances of Ar, S, and Ne were deduced. The complex G25.4-0.2 is only 5.5 kpc from the galactic center, and is considerably overabundant in all these elements. Complex G45.5+0.06 is at seven kpc from the galactic center, and appears to be approximately consistent with solar abundance. The complex S159 in the Perseus Arm, at 12 kpc from the galactic center, has solar abundance, while M8 in the solar neighborhood may be somewhat overabundant in Ar and Ne. Complex DR 22, at 10 kpc from the galactic center in the Cygnus Arm, is overabundant in Ar. A summary of results from a series of papers on abundances is given.
    Keywords: ASTROPHYSICS
    Type: Astrophysical Journal, Part 1 (ISSN 0004-637X); 285; 174-180
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  • 96
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    Statistical analysis of Thematic Mapper Simulator data for the geobotanical discrimination of rock types in southwest Oregon (1984)
    In:  Other Sources
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    Publication Date: 2011-08-19
    Description: An evaluation of Thematic Mapper Simulator (TMS) data for the geobotanical discrimination of rock types based on vegetative cover characteristics is addressed in this research. A methodology for accomplishing this evaluation utilizing univariate and multivariate techniques is presented. TMS data acquired with a Daedalus DEI-1260 multispectral scanner were integrated with vegetation and geologic information for subsequent statistical analyses, which included a chi-square test, an analysis of variance, stepwise discriminant analysis, and Duncan's multiple range test. Results indicate that ultramafic rock types are spectrally separable from nonultramafics based on vegetative cover through the use of statistical analyses.
    Keywords: EARTH RESOURCES AND REMOTE SENSING
    Type: IEEE Transactions on Geoscience and Remote Sensing (ISSN 0196-2892); GE-22; 525-530
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  • 97
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    Feature selection and the information content of Thematic Mapper simulator data for forest structural assessment (1984)
    In:  Other Sources
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    Publication Date: 2011-08-19
    Description: An assessment is made of the information content of Thematic Mapper Simulator (TMS) data for the case of a forested region, in order to determine the sensitivity of such data to forest crown closure and tree size class. Principal components analysis and Monte Carlo simulation indicated that channels 4, 7, 5 and 3 were optimal for four-channel forest structure analysis. As the number of channels supplied to the Monte Carlo feature selection routine increased, classification accuracy increased. The greatest sensitivity to the forest structural parameters, which included succession within clearcuts as well as crown closure and size class, was obtained from the 7-channel TMS data.
    Keywords: EARTH RESOURCES AND REMOTE SENSING
    Type: IEEE Transactions on Geoscience and Remote Sensing (ISSN 0196-2892); GE-22; 482-489
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  • 98
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    A summary of the history of the development of automated remote sensing for agricultural applications (1984)
    In:  Other Sources
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    Publication Date: 2011-08-19
    Description: An historical account is given of the development of technology for the processing of satellite-acquired multispectral data aimed at the identification of the type, condition, and ontogenic stages of agricultural areas. During 1972 and 1973, research established the feasibility of automating digital classification for the processing of large volumes of Landsat MSS data. This capability was successfully demonstrated during the Large Area Crop Inventory Experiment, which estimated wheat crop production on a global basis. This achievement in turn led to the Agriculture and Resources Inventory Surveys Through Aerospace Remote Sensing, which investigated other portions of the electromagnetic spectrum and expanded the study of key commercial crops in important agricultural areas.
    Keywords: EARTH RESOURCES AND REMOTE SENSING
    Type: IEEE Transactions on Geoscience and Remote Sensing (ISSN 0196-2892); GE-22; 473-482
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  • 99
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    Intense X-ray flares from active stellar systems - EV Lacertae and HD 8357 (1984)
    In:  Other Sources
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    Publication Date: 2011-08-19
    Description: The HEAO A-1 Sky Survey Experiment included X-ray data used to define light curves for the flare star EV Lac and for X-ray flares observed in the binary system HD 8357. The data were taken during flare events and were detailed enough to calculate the flare rates and flaring luminosities. The peak luminosities during flares were several times the luminosities in normal X-ray flares emitted by the objects. Peak luminosities reached 30-50 times the normal variations and were associated with an order of magnitude increase in energy output. EV Lac was sufficiently active to be recommended for inclusion in future X-ray monitoring programs.
    Keywords: ASTROPHYSICS
    Type: Astrophysical Journal, Part 1 (ISSN 0004-637X); 284; 270-277
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  • 100
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    Regularized Monte-Carlo calculations of the optical polarization induced by scattering in X-ray binaries (1984)
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    Publication Date: 2011-08-19
    Description: The results of regularized Monte Carlo calculations of the optical polarization Stokes parameters expected as a result of scattering from gas streams or accretion wakes in close binary systems whose properties resemble those of X-ray binaries are presented. The physical processes occurring in the system are represented by a model which follows a selected sample of individual photon paths from each emitting element on the surface of the primary to the photon's detection at earth. The result represents the variations in the intensity from each individual emitting element caused by the effects of limb darkening, gravity darkening, and variation in the projected area of the emitting element as seen from the scattering element.
    Keywords: ASTROPHYSICS
    Type: Astronomy and Astrophysics (ISSN 0004-6361); 138; 1, Se
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