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  • Adult  (30)
  • American Association for the Advancement of Science (AAAS)  (30)
  • 1980-1984  (30)
  • 1950-1954
  • 1935-1939
  • 1981  (30)
Collection
Publisher
  • American Association for the Advancement of Science (AAAS)  (30)
Years
  • 1980-1984  (30)
  • 1950-1954
  • 1935-1939
Year
  • 1
    Publication Date: 1981-08-21
    Description: A new technique has been developed for identifying, in humans, dynamic spatiotemporal electrical patterns of the brain during purposive behaviors. In this method, single-trial time-series correlations between brain macropotentials recorded from different scalp sites are analyzed by distribution-independent mathematical pattern recognition. Dynamic patterns of correlation clearly distinguished two brief visuomotor tasks differing only in type of mental judgement required (spatial or numeric). These complex patterns shifted in the anterior-posterior and left-right axes between successive 175-millisecond intervals, indicating that many areas in both cerebral hemispheres were involved even in these simple judgements. These patterns were not obtainable by conventional analysis of averaged evoked potentials or by linear analysis of correlations, suggesting that the new technique will advance the study of human brain activity related to cognition and goal-directed behaviors.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Gevins, A S -- Doyle, J C -- Cutillo, B A -- Schaffer, R E -- Tannehill, R S -- Ghannam, J H -- Gilcrease, V A -- Yeager, C L -- New York, N.Y. -- Science. 1981 Aug 21;213(4510):918-22.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/7256287" target="_blank"〉PubMed〈/a〉
    Keywords: Adult ; Brain/*physiology ; *Cognition ; Electroencephalography ; *Evoked Potentials ; Female ; Humans ; Male ; Pattern Recognition, Visual/physiology
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
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  • 2
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    American Association for the Advancement of Science (AAAS)
    Publication Date: 1981-03-20
    Description: Gender identity depends largely on postnatal environmental influences, while sex-dimorphic behavior and temperamental sex differences appear to be modified by prenatal sex hormones. A role of the prenatal endocrine milieu in the development of erotic partner preference, as in hetero-, homo-, or bisexual orientation, or of cognitive sex differences has not been conclusively demonstrated.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Ehrhardt, A A -- Meyer-Bahlburg, H F -- New York, N.Y. -- Science. 1981 Mar 20;211(4488):1312-8.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/7209510" target="_blank"〉PubMed〈/a〉
    Keywords: Adolescent ; Adrenal Hyperplasia, Congenital/metabolism/psychology ; Adult ; Androgens/pharmacology ; Behavior/drug effects ; Child ; Cognition/drug effects ; Embryo, Mammalian/drug effects ; Estrogens/pharmacology ; Female ; *Gender Identity ; Gonadal Steroid Hormones/*pharmacology ; Humans ; *Identification (Psychology) ; Male ; Pregnancy ; Pregnancy Complications/drug therapy ; Progestins/pharmacology/therapeutic use ; Sexual Behavior/*drug effects
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    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
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  • 3
    Publication Date: 1981-09-18
    Description: 〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Goldberg, E -- Antin, S P -- Bilder, R M Jr -- Gerstman, L J -- Hughes, J E -- Mattis, S -- New York, N.Y. -- Science. 1981 Sep 18;213(4514):1392-4.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/7268442" target="_blank"〉PubMed〈/a〉
    Keywords: Adult ; Amnesia/etiology/*physiopathology ; Amnesia, Retrograde/physiopathology ; Humans ; Male ; Memory/*physiology ; Mesencephalon/injuries/*physiopathology ; Skull Fractures/complications
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  • 4
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    American Association for the Advancement of Science (AAAS)
    Publication Date: 1981-11-27
    Description: Ten patients with multiple sclerosis who were treated with human fibroblast interferon (IFN-B) for 6 months showed a significant reduction in their exacerbation rates compared with their rates before treatment (P 〈 .01). The IFN-B was administered intrathecally by serial lumbar punctures. There was no significant change in the exacerbation rates of ten multiple sclerosis control patients before and during the period of observation. The IFN-B recipients have now been on the study a mean of 1.5 years, the controls, 1.2 years. The clinical condition of five of the IFN-B recipients and one of the control patients has improved, whereas the condition of five of the controls and one of the IFN-B recipients has deteriorated (P 〈 .036). These findings warrant cautious optimism about the efficacy of intrathecal IFN-B in altering the course of multiple sclerosis and support concepts of a viral or dysimmune etiology of the disease.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Jacobs, L -- O'Malley, J -- Freeman, A -- Ekes, R -- CA-18533/CA/NCI NIH HHS/ -- New York, N.Y. -- Science. 1981 Nov 27;214(4524):1026-8.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/6171035" target="_blank"〉PubMed〈/a〉
    Keywords: Adolescent ; Adult ; Clinical Trials as Topic ; Female ; Fibroblasts ; Follow-Up Studies ; Humans ; Interferons/*therapeutic use ; Male ; Multiple Sclerosis/*drug therapy
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  • 5
    Publication Date: 1981-04-17
    Description: Sensory and cognitive functions were assessed in a right-handed male before and after partial and complete callosal commissurotomy. After the initial posterior section was made, there was no evidence of interhemispheric sensory transfer, although the left hemisphere did have access to stimulus-related semantic and episodic information from the right hemisphere. After the callosum was completely sectioned, this exchange was no longer observed.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Sidtis, J J -- Volpe, B T -- Holtzman, J D -- Wilson, D H -- Gazzaniga, M S -- 2 R01 NS15053-02/NS/NINDS NIH HHS/ -- RR001-02/RR/NCRR NIH HHS/ -- New York, N.Y. -- Science. 1981 Apr 17;212(4492):344-6.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/6782673" target="_blank"〉PubMed〈/a〉
    Keywords: Adult ; Cognition/*physiology ; Cognition Disorders/*physiopathology ; Corpus Callosum/*physiology/surgery ; Epilepsy, Tonic-Clonic/surgery ; Humans ; Language Disorders/*physiopathology ; Male ; Methods ; Perception/physiology ; Perceptual Disorders/*physiopathology ; Postoperative Complications/physiopathology ; Sensation/*physiology
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  • 6
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    American Association for the Advancement of Science (AAAS)
    Publication Date: 1981-04-03
    Description: 〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Wade, N -- New York, N.Y. -- Science. 1981 Apr 3;212(4490):24-5.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/6259731" target="_blank"〉PubMed〈/a〉
    Keywords: Adolescent ; Adult ; *DNA, Recombinant ; *Ethics Committees, Research ; *Ethics, Medical ; Federal Government ; Female ; *Genetic Engineering/history ; Genetic Vectors ; Globins/genetics ; Government Regulation ; History, 20th Century ; Humans ; Informed Consent ; Israel ; Plasmids ; Thalassemia/*therapy ; United States
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  • 7
    Publication Date: 1981-02-06
    Description: Arginine vasopressin and a number of its synthetic analogs augment memory functions in experimental animals. One of these analogs, 1-desamino-8-D-arginine vasopressin (DDAVP), influences human learning and memory. Cognitively unimpaired, as well as cognitively impaired adults, treated with DDAVP for a period of several days, learn information more effectively, as measured by the completeness, organization, and consistency (reliability) of recall. DDAVP also appears to reverse partially the retrograde amnesia that follows electroconvulsive treatment.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Weingartner, H -- Gold, P -- Ballenger, J C -- Smallberg, S A -- Summers, R -- Rubinow, D R -- Post, R M -- Goodwin, F K -- New York, N.Y. -- Science. 1981 Feb 6;211(4482):601-3.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/7455701" target="_blank"〉PubMed〈/a〉
    Keywords: Adult ; Arginine Vasopressin/*pharmacology ; Cognition/drug effects ; Deamino Arginine Vasopressin/pharmacology ; Depression/physiopathology ; Female ; Humans ; Learning/*drug effects ; Male ; Memory/*drug effects ; Middle Aged
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  • 8
    Publication Date: 1981-05-08
    Description: The cumulative effects of a repetitive stress induced by anticipation of pain (noxious foot shock) were studied on the threshold of a nociceptive flexion reflex of the lower limb. The threshold of the nociceptive reflex progressively increased with the repetition of the stress. This effect was reversed by naloxone, which even produced hyperalgesia, since a rapid and significant decrease in this threshold, below the initial values, was noted. Tha data provide evidence for involvement of endogenous opioids in the phenomenon of stress-induced analgesia in normal man.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Willer, J C -- Dehen, H -- Cambier, J -- New York, N.Y. -- Science. 1981 May 8;212(4495):689-91.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/6261330" target="_blank"〉PubMed〈/a〉
    Keywords: Adult ; Female ; Humans ; Male ; Naloxone/pharmacology ; Pain/*physiopathology ; Receptors, Opioid/*physiology ; Reflex/drug effects ; Stress, Psychological/*physiopathology
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  • 9
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    American Association for the Advancement of Science (AAAS)
    Publication Date: 1981-06-19
    Description: 〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉New York, N.Y. -- Science. 1981 Jun 19;212(4501):1416-8.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/7233233" target="_blank"〉PubMed〈/a〉
    Keywords: Adult ; Female ; Foot/*anatomy & histology ; *Functional Laterality ; Humans ; Male ; Sex Factors
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  • 10
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    American Association for the Advancement of Science (AAAS)
    Publication Date: 1981-12-04
    Description: 〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Antelman, S M -- Rowland, N -- New York, N.Y. -- Science. 1981 Dec 4;214(4525):1149-51.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/7302588" target="_blank"〉PubMed〈/a〉
    Keywords: Adult ; Animals ; Endorphins/*physiology ; Feeding Behavior/drug effects/*physiology ; Humans ; Naloxone/pharmacology ; Rats ; Rats, Inbred Strains ; Stress, Psychological/*physiopathology
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  • 11
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    American Association for the Advancement of Science (AAAS)
    Publication Date: 1981-08-07
    Description: Subjects observing differently scaled environments undergo systematic shifts in the experience of time. The experience of temporal duration is compressed relative to the clock in the same proportion as scale-model environments being observed are compressed relative to the full-sized environment. This research suggests that spatial scale may be a principal mediator in the experience of time.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉DeLong, A J -- RR-07088/RR/NCRR NIH HHS/ -- New York, N.Y. -- Science. 1981 Aug 7;213(4508):681-3.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/7256273" target="_blank"〉PubMed〈/a〉
    Keywords: Adult ; *Environment ; Humans ; Time Perception/*physiology
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  • 12
    Publication Date: 1981-05-08
    Description: The 2-[18F]fluoro-2-deoxy-D-glucose technique was used to measure regional cerebral glucose utilization by human subjects during functional activation. Normal male volunteers subjected to one or more sensory stimuli (tactile, visual, or auditory) exhibited focal increases in glucose metabolism in response to the stimulus. Unilateral visual hemifield stimulation caused the contralateral striate cortex to become more metabolically active than the striate cortex ipsilateral to the stimulated hemifield. Similarly, stroking the fingers and hand of one arm with brush produced an increase in metabolism in the contralateral postcentral gyrus, compared with the homologous ipsilateral region. The auditory stimulus, which consisted of a monaurally presented factual story caused an increase in glucose metabolism in the auditory cortex in the hemisphere contralateral to the stimulated ear. These results demonstrate that the technique is capable of providing functional maps in vivo related to both body region and submodality of sensory information in the human brain.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Greenberg, J H -- Reivich, M -- Alavi, A -- Hand, P -- Rosenquist, A -- Rintelmann, W -- Stein, A -- Tusa, R -- Dann, R -- Christman, D -- Fowler, J -- MacGregor, B -- Wolf, A -- NS 10939-08/NS/NINDS NIH HHS/ -- NS 14867-02/NS/NINDS NIH HHS/ -- NS 15380-04/NS/NINDS NIH HHS/ -- New York, N.Y. -- Science. 1981 May 8;212(4495):678-80.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/6971492" target="_blank"〉PubMed〈/a〉
    Keywords: Adult ; Auditory Perception/*physiology ; Brain/*metabolism ; *Deoxy Sugars ; *Deoxyglucose/analogs & derivatives/metabolism ; Fluorodeoxyglucose F18 ; Functional Laterality ; Humans ; Male ; Sensation/*physiology ; Tomography, Emission-Computed/*methods ; Visual Perception/*physiology
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  • 13
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    American Association for the Advancement of Science (AAAS)
    Publication Date: 1981-01-16
    Description: 〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Holden, C -- New York, N.Y. -- Science. 1981 Jan 16;211(4479):257.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/7444464" target="_blank"〉PubMed〈/a〉
    Keywords: Adult ; *Aerospace Medicine ; Altitude ; *Anemia, Sickle Cell ; Humans ; Jurisprudence ; Male ; *Military Medicine ; Risk ; *Sickle Cell Trait
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  • 14
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    American Association for the Advancement of Science (AAAS)
    Publication Date: 1981-05-29
    Description: 〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Marshal, E -- New York, N.Y. -- Science. 1981 May 29;212(4498):1008.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/7233195" target="_blank"〉PubMed〈/a〉
    Keywords: Adult ; *Cultural Characteristics ; *Culture ; Female ; Humans ; Laos/ethnology ; Male ; Middle Aged ; *Mortality ; Refugees/*psychology ; Stress, Physiological ; United States
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  • 15
    Publication Date: 1981-12-04
    Description: Leucine catabolism is regulated by either of the first two degradative steps: (reversible) transamination to the keto acid or subsequent decarboxylation. A method is described to measure rates of leucine transamination, reamination, and keto acid oxidation. The method is applied directly to humans by infusing the nonradioactive tracer, L-[15N,1-13C]leucine. Leucine transamination was found to be operating several times faster than the keto acid decarboxylation and to be of equal magnitude in adult human males under two different dietary conditions, postabsorptive and fed. These results indicate that decarboxylation, not transamination, is the rate-limiting step in normal human leucine metabolism.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Matthews, D E -- Bier, D M -- Rennie, M J -- Edwards, R H -- Halliday, D -- Millward, D J -- Clugston, G A -- AM-25994/AM/NIADDK NIH HHS/ -- HD-10667/HD/NICHD NIH HHS/ -- RR-00954/RR/NCRR NIH HHS/ -- New York, N.Y. -- Science. 1981 Dec 4;214(4525):1129-31.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/7302583" target="_blank"〉PubMed〈/a〉
    Keywords: Adult ; Carbon Isotopes ; Humans ; Kinetics ; Leucine/*metabolism ; Male ; Models, Biological ; Nitrogen Isotopes ; Oxidation-Reduction
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  • 16
    Publication Date: 1981-06-19
    Description: Twenty-five chemical workers who manufactured polybrominated biphenyls (PBB's) were given objective tests of learning and memory. Although this group had high concentrations of PBB's in adipose tissue, mean scores on all memory tests were normal. The PBB concentration was not correlated with memory performance; the most contaminated workers showed no evidence of memory dysfunction.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Brown, G G -- Preisman, R C -- Anderson, M D -- Nixon, R K -- Isbister, J L -- Price, H A -- New York, N.Y. -- Science. 1981 Jun 19;212(4501):1413-5.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/6262920" target="_blank"〉PubMed〈/a〉
    Keywords: Adult ; Biphenyl Compounds/*adverse effects ; Humans ; Learning/*drug effects ; Memory/*drug effects ; Polybrominated Biphenyls/*adverse effects ; Psychological Tests
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  • 17
    Publication Date: 1981-01-30
    Description: The densities of the brains of 11 chronic alcoholics were compared with those of 11 age-matched normal control subjects. Densities were determined from the density numbers generated by computerized tomography at three levels of the brain-the highest level of the lateral ventricles and the next two higher levels-with adjustments made to control for possible artifacts in the data. The advantage of the dominant hemisphere over the nondominant hemisphere was lessened in alcoholics.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Golden, C J -- Graber, B -- Blose, I -- Berg, R -- Coffman, J -- Bloch, S -- New York, N.Y. -- Science. 1981 Jan 30;211(4481):508-10.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/7455693" target="_blank"〉PubMed〈/a〉
    Keywords: Adult ; Alcoholism/*pathology ; Brain/*pathology ; Functional Laterality ; Humans ; Tomography, X-Ray Computed
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  • 18
    Publication Date: 1981-02-27
    Description: The concentration of norepinephrine in cerebrospinal fluid from patients with essential hypertension is higher than that from healthy normal volunteers, but the concentrations of norepinephrine in plasma from these groups are similar. This finding indicates that central nervous system noradrenergic hyperactivity occurs in essential hypertension but apparently is not reflected in abnormal function of the peripheral sympathetic nervous system in these patients.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Lake, C R -- Gullner, H G -- Polinsky, R J -- Ebert, M H -- Ziegler, M G -- Bartter, F C -- New York, N.Y. -- Science. 1981 Feb 27;211(4485):955-7.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/7466370" target="_blank"〉PubMed〈/a〉
    Keywords: Adult ; Blood Pressure ; Female ; Humans ; Hypertension/blood/*cerebrospinal fluid ; Middle Aged ; Norepinephrine/blood/*cerebrospinal fluid ; Posture
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  • 19
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    American Association for the Advancement of Science (AAAS)
    Publication Date: 1981-12-11
    Description: Sleep recordings were carried out on athletes on four successive nights after completing a 92-kilometer road race. Significant increases in total sleep time and slow-wave sleep were found after this metabolic stress. The results show a definite exercise effect on sleep and support sleep-restoration hypotheses.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Shapiro, C M -- Bortz, R -- Mitchell, D -- Bartel, P -- Jooste, P -- New York, N.Y. -- Science. 1981 Dec 11;214(4526):1253-4.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/7302594" target="_blank"〉PubMed〈/a〉
    Keywords: Adolescent ; Adult ; Humans ; *Physical Exertion ; Running ; Sleep Stages/*physiology ; Sleep, REM/physiology
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  • 20
    Publication Date: 1981-08-14
    Description: Sixteen former military personnel who were present at the "Smoky" atmospheric nuclear weapon test have been investigated for internal deposits of radioactivity. Whole-body and thorax gamma-ray measurements, thorax and skeletal actinide measurements, and urinalyses for plutonium-239 and strontium-90 indicated no evidence of radioactivity in excess of that found in the general population.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Toohey, R E -- Rundo, J -- Essling, M A -- Sha, J Y -- Oldham, R D -- Sedlet, J -- Robinson, J J -- New York, N.Y. -- Science. 1981 Aug 14;213(4509):767-8.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/7256278" target="_blank"〉PubMed〈/a〉
    Keywords: Adult ; Humans ; Middle Aged ; *Military Medicine ; Plutonium/urine ; *Radiation Monitoring ; Strontium Radioisotopes/urine ; United States
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  • 21
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    American Association for the Advancement of Science (AAAS)
    Publication Date: 1981-03-06
    Description: Auditory brainstem potentials were recorded from abstinent chronic alcoholics and control subjects. The latencies of peaks II, III, IV, and V were significantly delayed in the alcoholic patients compared to control subjects. Brainstem transmission time was longer in alcoholics than in controls. This study provides systematic evidence that chronic alcohol abuse results in brainstem deficits suggesting possible demyelination of auditory tracts.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Begleiter, H -- Porjesz, B -- Chou, C L -- AA 02686/AA/NIAAA NIH HHS/ -- New York, N.Y. -- Science. 1981 Mar 6;211(4486):1064-6.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/7466379" target="_blank"〉PubMed〈/a〉
    Keywords: Adult ; Alcoholism/*physiopathology ; Auditory Perception/*physiology ; Brain Stem/*physiopathology ; Evoked Potentials ; Humans ; Male ; Membrane Potentials
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    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
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  • 22
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    American Association for the Advancement of Science (AAAS)
    Publication Date: 1981-04-17
    Description: Event-related potentials following silently named object pictures were recorded directly from the exposed left hemisphere of the human cortex at sites whose relation to naming was subsequently established by electrical stimulation mapping. Two simultaneous potential changes are specific to sites where stimulation disrupts naming: slow potentials as premotor sites and focal desynchronization at posterior sites surrounding the Sylvian fissure. These anatomically specific changes are also specific to the task--present with silent naming and absent in a spatial task with the same visual input. Overt speech is also preceded by slow potentials with earliest onset at premotor sites.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Fried, I -- Ojemann, G A -- Fetz, E E -- NS 04053/NS/NINDS NIH HHS/ -- New York, N.Y. -- Science. 1981 Apr 17;212(4492):353-6.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/7209537" target="_blank"〉PubMed〈/a〉
    Keywords: Adult ; Cerebral Cortex/*physiology ; Electric Stimulation ; Evoked Potentials ; Female ; Frontal Lobe/physiology ; Humans ; Language/*physiology ; Male ; Middle Aged
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  • 23
    Publication Date: 1981-05-08
    Description: A tritium-labeled probe that detects measles virus nucleotide sequences was hybridized in situ to cells infected with measles virus and to sections of brain tissue from patients with subacute sclerosing panencephalitis and from patients with multiple sclerosis. The measles virus genome was detected in many cells in subacute sclerosing panencephalitis where this virus would have been missed by methods such as immunofluorescence. Measles virus sequences were also found in two foci in one of four cases of multiple sclerosis. This refined method of hybridization in situ, which can be useful in the search for covert virus infections of man, provides evidence that viruses may be involved in multiple sclerosis.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Haase, A T -- Ventura, P -- Gibbs, C J Jr -- Tourtellotte, W W -- New York, N.Y. -- Science. 1981 May 8;212(4495):672-5.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/7221554" target="_blank"〉PubMed〈/a〉
    Keywords: Adolescent ; Adult ; Aged ; Brain/microbiology ; Child ; Child, Preschool ; Female ; Humans ; Male ; Measles virus/*genetics ; Middle Aged ; Multiple Sclerosis/*microbiology ; Nucleic Acid Hybridization ; RNA, Viral/genetics ; Subacute Sclerosing Panencephalitis/*microbiology
    Print ISSN: 0036-8075
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    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
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  • 24
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    American Association for the Advancement of Science (AAAS)
    Publication Date: 1981-11-13
    Description: 〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Kolata, G B -- New York, N.Y. -- Science. 1981 Nov 13;214(4522):774-5.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/7027443" target="_blank"〉PubMed〈/a〉
    Keywords: Adult ; Aged ; Clinical Trials as Topic ; Humans ; Middle Aged ; Myocardial Infarction/drug therapy/*prevention & control ; Propranolol/adverse effects/*therapeutic use
    Print ISSN: 0036-8075
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  • 25
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    American Association for the Advancement of Science (AAAS)
    Publication Date: 1981-04-03
    Description: The binding of monoclonal antibody specific for colon carcinoma was inhibited by serum from patients with adenocarcinoma of the colon but not by serum from patients with other bowel diseases or from healthy volunteers. Of other malignancies studied, serum from two patients with gastric carcinoma and two patients with pancreatic carcinoma also inhibited the specific binding of monoclonal antibody. The levels of carcinoembryonic antigen in these serum samples were not correlated with their levels of binding inhibition. Such monoclonal antibodies may prove useful for the detection of colorectal carcinoma.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Koprowski, H -- Herlyn, M -- Steplewski, Z -- Sears, H F -- CA-21124/CA/NCI NIH HHS/ -- RR-05540/RR/NCRR NIH HHS/ -- New York, N.Y. -- Science. 1981 Apr 3;212(4490):53-5.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/6163212" target="_blank"〉PubMed〈/a〉
    Keywords: Adenocarcinoma/*immunology ; Adult ; Aged ; Antibodies, Neoplasm/immunology ; Antibody Specificity ; Antigens, Neoplasm/*analysis ; Binding, Competitive ; Carcinoembryonic Antigen/analysis ; Cells, Cultured ; Colonic Neoplasms/*immunology ; Epitopes ; Female ; Humans ; Intestinal Diseases/immunology ; Male ; Middle Aged ; Neoplasms/immunology
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    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
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  • 26
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    American Association for the Advancement of Science (AAAS)
    Publication Date: 1981-08-07
    Description: Circadian rhythms of ionized calcium and phosphate concentrations have been demonstrated in human blood. A computer-derived model curve representing the 24-hour fluctuations in ionized calcium cannot be correlated consistently with curves for total calcium or phosphate. Knowledge of these circadian rhythms provides a physiological basis for further understanding the interactions between blood minerals and calcium-regulating hormones.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Markowitz, M -- Rotkin, L -- Rosen, J F -- ES-01060-06/ES/NIEHS NIH HHS/ -- RR-53/RR/NCRR NIH HHS/ -- New York, N.Y. -- Science. 1981 Aug 7;213(4508):672-4.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/7256269" target="_blank"〉PubMed〈/a〉
    Keywords: Adult ; Calcium/*blood ; *Circadian Rhythm ; Humans ; Male ; Phosphates/*blood
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    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
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  • 27
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    American Association for the Advancement of Science (AAAS)
    Publication Date: 1981-04-17
    Description: The auditory brainstem response varies in a circadian rhythm that is negatively correlated with the circadian rhythm in oral temperature. The auditory brainstem responses and oral temperature were recorded every 3 hours from three healthy male subjects during a 2-day period. The data indicate that a reduction of 1 degree C in oral temperature is associated with an increase of 200 microseconds in the latency of wave V of the auditory brainstem response, and of 160 microseconds in the interval between waves I and V.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Marshall, N K -- Donchin, E -- New York, N.Y. -- Science. 1981 Apr 17;212(4492):356-8.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/7209538" target="_blank"〉PubMed〈/a〉
    Keywords: Adult ; *Body Temperature ; Brain Stem/*physiology ; *Circadian Rhythm ; Evoked Potentials, Auditory ; Humans ; Male ; Time Factors
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    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
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  • 28
    Publication Date: 1981-03-27
    Description: These studies demonstrated increasing glucose metabolic rates in the human primary (PVC) and associative (AVC) visual cortex as the complexity of visual scenes increased. The metabolic response of the AVC increased more rapidly with scene complexity than that of the PVC, indicating the greater involvement of the higher order AVC for complex visual interpretations. Increases in local metabolic activity by as much as a factor of 2 above that of control subjects with eyes closed indicate the wide range and metabolic reserve of the visual cortex.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Phelps, M E -- Kuhl, D E -- Mazziota, J C -- P0-NS 156540-01/NS/NINDS NIH HHS/ -- R0I-GM-24839-01/GM/NIGMS NIH HHS/ -- New York, N.Y. -- Science. 1981 Mar 27;211(4489):1445-8.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/6970412" target="_blank"〉PubMed〈/a〉
    Keywords: Adult ; Deoxy Sugars/*metabolism ; Deoxyglucose/analogs & derivatives/*metabolism ; Fluorodeoxyglucose F18 ; Humans ; Photic Stimulation ; Tomography, Emission-Computed ; Visual Cortex/*metabolism/physiology/radionuclide imaging
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    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
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  • 29
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    American Association for the Advancement of Science (AAAS)
    Publication Date: 1981-07-24
    Description: Neuropsychological variables and urine cannabinoid metabolites were evaluated in ten subjects born, raised, and educated in the United States and having histories of heavy or prolonged use of cannabis. No impairment of cognitive function was found. Cannabinoid metabolites in excess of 50 nanograms per milliliter were present in the ten urine samples. The tetrahydrocannabinol content of cannabis exceeded 8.0%.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Schaeffer, J -- Andrysiak, T -- Ungerleider, J T -- New York, N.Y. -- Science. 1981 Jul 24;213(4506):465-6.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/6972600" target="_blank"〉PubMed〈/a〉
    Keywords: Adult ; Cannabinoids/*pharmacology/urine ; Cognition/*drug effects ; Female ; Humans ; Male ; Marijuana Abuse/*psychology
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    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
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  • 30
    Publication Date: 1981-03-06
    Description: Eight chronic schizophrenia patients completed a research program consisting of ten weekly sessions of active hemodialysis and ten weekly sessions of sham dialysis in a double-blind design. Previous reports of therapeutic efficacy were not substantiated. None of the patients improved during active dialysis; four patients worsened.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Schulz, S C -- van Kammen, D P -- Balow, J E -- Flye, M W -- Bunney, W E Jr -- New York, N.Y. -- Science. 1981 Mar 6;211(4486):1066-8.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/7466380" target="_blank"〉PubMed〈/a〉
    Keywords: Adult ; Double-Blind Method ; Female ; Humans ; Male ; *Renal Dialysis ; Schizophrenia/*therapy ; Sex Factors
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    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
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