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  • 11
    Publication Date: 2006-06-03
    Description: The ranging instrument aboard the Hayabusa spacecraft measured the surface topography of asteroid 25143 Itokawa and its mass. A typical rough area is similar in roughness to debris located on the interior wall of a large crater on asteroid 433 Eros, which suggests a surface structure on Itokawa similar to crater ejecta on Eros. The mass of Itokawa was estimated as (3.58 +/- 0.18) x 10(10) kilograms, implying a bulk density of (1.95 +/- 0.14) grams per cubic centimeter for a volume of (1.84 +/- 0.09) x 10(7) cubic meters and a bulk porosity of approximately 40%, which is similar to that of angular sands, when assuming an LL (low iron chondritic) meteorite composition. Combined with surface observations, these data indicate that Itokawa is the first subkilometer-sized small asteroid showing a rubble-pile body rather than a solid monolithic asteroid.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Abe, Shinsuke -- Mukai, Tadashi -- Hirata, Naru -- Barnouin-Jha, Olivier S -- Cheng, Andrew F -- Demura, Hirohide -- Gaskell, Robert W -- Hashimoto, Tatsuaki -- Hiraoka, Kensuke -- Honda, Takayuki -- Kubota, Takashi -- Matsuoka, Masatoshi -- Mizuno, Takahide -- Nakamura, Ryosuke -- Scheeres, Daniel J -- Yoshikawa, Makoto -- New York, N.Y. -- Science. 2006 Jun 2;312(5778):1344-7.〈br /〉〈span class="detail_caption"〉Author address: 〈/span〉Graduate School of Science and Technology, Kobe University, Nada, Kobe 657-8501, Japan. avell@kobe-u.ac.jp〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/16741111" target="_blank"〉PubMed〈/a〉
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  • 12
    Publication Date: 2007-01-27
    Description: Vitamin A has diverse biological functions. It is transported in the blood as a complex with retinol binding protein (RBP), but the molecular mechanism by which vitamin A is absorbed by cells from the vitamin A-RBP complex is not clearly understood. We identified in bovine retinal pigment epithelium cells STRA6, a multitransmembrane domain protein, as a specific membrane receptor for RBP. STRA6 binds to RBP with high affinity and has robust vitamin A uptake activity from the vitamin A-RBP complex. It is widely expressed in embryonic development and in adult organ systems. The RBP receptor represents a major physiological mediator of cellular vitamin A uptake.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Kawaguchi, Riki -- Yu, Jiamei -- Honda, Jane -- Hu, Jane -- Whitelegge, Julian -- Ping, Peipei -- Wiita, Patrick -- Bok, Dean -- Sun, Hui -- 5T32EY07026/EY/NEI NIH HHS/ -- New York, N.Y. -- Science. 2007 Feb 9;315(5813):820-5. Epub 2007 Jan 25.〈br /〉〈span class="detail_caption"〉Author address: 〈/span〉Department of Physiology, David Geffen School of Medicine at UCLA, 650 Charles E. Young Drive South, Los Angeles, CA 90095, USA.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/17255476" target="_blank"〉PubMed〈/a〉
    Keywords: Acyltransferases/metabolism ; Amino Acid Sequence ; Animals ; Blood-Retinal Barrier ; COS Cells ; Cattle ; Cell Line ; Cell Line, Tumor ; Cell Membrane/metabolism ; Cercopithecus aethiops ; Embryonic Development ; Endocytosis ; Humans ; Molecular Sequence Data ; Mutation, Missense ; Pigment Epithelium of Eye/*metabolism ; Placenta/metabolism ; Receptors, Cell Surface/*metabolism ; Retinal Vessels/metabolism ; Retinol-Binding Proteins/*metabolism ; Spleen/metabolism ; Transfection ; Vitamin A/*metabolism
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  • 13
    Publication Date: 2007-04-28
    Description: The oceanic biological pump drives sequestration of carbon dioxide in the deep sea via sinking particles. Rapid biological consumption and remineralization of carbon in the "twilight zone" (depths between the euphotic zone and 1000 meters) reduce the efficiency of sequestration. By using neutrally buoyant sediment traps to sample this chronically understudied realm, we measured a transfer efficiency of sinking particulate organic carbon between 150 and 500 meters of 20 and 50% at two contrasting sites. This large variability in transfer efficiency is poorly represented in biogeochemical models. If applied globally, this is equivalent to a difference in carbon sequestration of more than 3 petagrams of carbon per year.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Buesseler, Ken O -- Lamborg, Carl H -- Boyd, Philip W -- Lam, Phoebe J -- Trull, Thomas W -- Bidigare, Robert R -- Bishop, James K B -- Casciotti, Karen L -- Dehairs, Frank -- Elskens, Marc -- Honda, Makio -- Karl, David M -- Siegel, David A -- Silver, Mary W -- Steinberg, Deborah K -- Valdes, Jim -- Van Mooy, Benjamin -- Wilson, Stephanie -- New York, N.Y. -- Science. 2007 Apr 27;316(5824):567-70.〈br /〉〈span class="detail_caption"〉Author address: 〈/span〉Department of Marine Chemistry and Geochemistry, Woods Hole Oceanographic Institution, Woods Hole, MA 02543, USA. kbuesseler@whoi.edu〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/17463282" target="_blank"〉PubMed〈/a〉
    Keywords: Animals ; *Carbon/metabolism ; Carbon Dioxide ; Copepoda/physiology ; *Ecosystem ; Food Chain ; Geologic Sediments/chemistry ; Hydrogen-Ion Concentration ; Pacific Ocean ; Phytoplankton/physiology ; *Seawater/chemistry ; Zooplankton/physiology
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  • 14
    Publication Date: 2008-10-25
    Description: The inside of Shackleton Crater at the lunar south pole is permanently shadowed; it has been inferred to hold water-ice deposits. The Terrain Camera (TC), a 10-meter-resolution stereo camera onboard the Selenological and Engineering Explorer (SELENE) spacecraft, succeeded in imaging the inside of the crater, which was faintly lit by sunlight scattered from the upper inner wall near the rim. The estimated temperature of the crater floor, based on the crater shape model derived from the TC data, is less than approximately 90 kelvin, cold enough to hold water-ice. However, at the TC's spatial resolution, the derived albedo indicates that exposed relatively pure water-ice deposits are not on the crater floor. Water-ice may be disseminated and mixed with soil over a small percentage of the area or may not exist at all.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Haruyama, Junichi -- Ohtake, Makiko -- Matsunaga, Tsuneo -- Morota, Tomokatsu -- Honda, Chikatoshi -- Yokota, Yasuhiro -- Pieters, Carle M -- Hara, Seiichi -- Hioki, Kazuyuki -- Saiki, Kazuto -- Miyamoto, Hideaki -- Iwasaki, Akira -- Abe, Masanao -- Ogawa, Yoshiko -- Takeda, Hiroshi -- Shirao, Motomaro -- Yamaji, Atsushi -- Josset, Jean-Luc -- New York, N.Y. -- Science. 2008 Nov 7;322(5903):938-9. doi: 10.1126/science.1164020. Epub 2008 Oct 23.〈br /〉〈span class="detail_caption"〉Author address: 〈/span〉Institute of Space and Astronautical Science, Japan Aerospace Exploration Agency, Sagamihara, Kanagawa 229-85105, Japan.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/18948501" target="_blank"〉PubMed〈/a〉
    Keywords: Cold Temperature ; Extraterrestrial Environment ; *Ice ; *Moon ; Spacecraft
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  • 15
    Publication Date: 2011-01-06
    Description: CD4(+) T regulatory cells (T(regs)), which express the Foxp3 transcription factor, play a critical role in the maintenance of immune homeostasis. Here, we show that in mice, T(regs) were most abundant in the colonic mucosa. The spore-forming component of indigenous intestinal microbiota, particularly clusters IV and XIVa of the genus Clostridium, promoted T(reg) cell accumulation. Colonization of mice by a defined mix of Clostridium strains provided an environment rich in transforming growth factor-beta and affected Foxp3(+) T(reg) number and function in the colon. Oral inoculation of Clostridium during the early life of conventionally reared mice resulted in resistance to colitis and systemic immunoglobulin E responses in adult mice, suggesting a new therapeutic approach to autoimmunity and allergy.〈br /〉〈br /〉〈a href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3969237/" target="_blank"〉〈img src="https://static.pubmed.gov/portal/portal3rc.fcgi/4089621/img/3977009" border="0"〉〈/a〉   〈a href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3969237/" target="_blank"〉This paper as free author manuscript - peer-reviewed and accepted for publication〈/a〉〈br /〉〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Atarashi, Koji -- Tanoue, Takeshi -- Shima, Tatsuichiro -- Imaoka, Akemi -- Kuwahara, Tomomi -- Momose, Yoshika -- Cheng, Genhong -- Yamasaki, Sho -- Saito, Takashi -- Ohba, Yusuke -- Taniguchi, Tadatsugu -- Takeda, Kiyoshi -- Hori, Shohei -- Ivanov, Ivaylo I -- Umesaki, Yoshinori -- Itoh, Kikuji -- Honda, Kenya -- R00 DK085329/DK/NIDDK NIH HHS/ -- R01 AI052359/AI/NIAID NIH HHS/ -- R01 AI056154/AI/NIAID NIH HHS/ -- New York, N.Y. -- Science. 2011 Jan 21;331(6015):337-41. doi: 10.1126/science.1198469. Epub 2010 Dec 23.〈br /〉〈span class="detail_caption"〉Author address: 〈/span〉Department of Immunology, Graduate School of Medicine, University of Tokyo, Tokyo 113-0033, Japan.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/21205640" target="_blank"〉PubMed〈/a〉
    Keywords: Animals ; Anti-Bacterial Agents/pharmacology ; Cecum/microbiology ; Cells, Cultured ; Clostridium/growth & development/*immunology ; Colitis/immunology/pathology/prevention & control ; Colon/*immunology/metabolism/*microbiology ; Feces/microbiology ; Forkhead Transcription Factors/metabolism ; Germ-Free Life ; Immunity, Innate ; Immunoglobulin E/biosynthesis ; Interleukin-10/immunology/metabolism ; Intestinal Mucosa/*immunology/metabolism ; Intestine, Small/immunology ; Metagenome ; Mice ; Mice, Inbred A ; Mice, Inbred BALB C ; Receptors, Pattern Recognition/physiology ; Specific Pathogen-Free Organisms ; T-Lymphocytes, Helper-Inducer/immunology ; T-Lymphocytes, Regulatory/*immunology/metabolism ; Transforming Growth Factor beta/metabolism
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  • 16
    Publication Date: 1997-12-05
    Description: Studies of the ground and excited states in semiconductor quantum dots containing 1 to 12 electrons showed that the quantum numbers of the states in the excitation spectra can be identified and compared with exact calculations. A magnetic field induces transitions between the ground and excited states. These transitions were analyzed in terms of crossings between single-particle states, singlet-triplet transitions, spin polarization, and Hund's rule. These impurity-free quantum dots allow "atomic physics" experiments to be performed in magnetic field regimes not accessible for atoms.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Kouwenhoven -- Oosterkamp -- Danoesastro -- Eto -- Austing -- Honda -- Tarucha -- New York, N.Y. -- Science. 1997 Dec 5;278(5344):1788-92.〈br /〉〈span class="detail_caption"〉Author address: 〈/span〉L. P. Kouwenhoven, T. H. Oosterkamp, M. W. S. Danoesastro, Department of Applied Physics and Delft Institute of MicroElectronics and Submicrontechnology, Delft University of Technology, Post Office Box 5046, 2600 GA Delf.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/9388179" target="_blank"〉PubMed〈/a〉
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  • 17
    Publication Date: 2005-09-10
    Description: On 4 July 2005, many observatories around the world and in space observed the collision of Deep Impact with comet 9P/Tempel 1 or its aftermath. This was an unprecedented coordinated observational campaign. These data show that (i) there was new material after impact that was compositionally different from that seen before impact; (ii) the ratio of dust mass to gas mass in the ejecta was much larger than before impact; (iii) the new activity did not last more than a few days, and by 9 July the comet's behavior was indistinguishable from its pre-impact behavior; and (iv) there were interesting transient phenomena that may be correlated with cratering physics.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Meech, K J -- Ageorges, N -- A'Hearn, M F -- Arpigny, C -- Ates, A -- Aycock, J -- Bagnulo, S -- Bailey, J -- Barber, R -- Barrera, L -- Barrena, R -- Bauer, J M -- Belton, M J S -- Bensch, F -- Bhattacharya, B -- Biver, N -- Blake, G -- Bockelee-Morvan, D -- Boehnhardt, H -- Bonev, B P -- Bonev, T -- Buie, M W -- Burton, M G -- Butner, H M -- Cabanac, R -- Campbell, R -- Campins, H -- Capria, M T -- Carroll, T -- Chaffee, F -- Charnley, S B -- Cleis, R -- Coates, A -- Cochran, A -- Colom, P -- Conrad, A -- Coulson, I M -- Crovisier, J -- deBuizer, J -- Dekany, R -- de Leon, J -- Dello Russo, N -- Delsanti, A -- DiSanti, M -- Drummond, J -- Dundon, L -- Etzel, P B -- Farnham, T L -- Feldman, P -- Fernandez, Y R -- Filipovic, M D -- Fisher, S -- Fitzsimmons, A -- Fong, D -- Fugate, R -- Fujiwara, H -- Fujiyoshi, T -- Furusho, R -- Fuse, T -- Gibb, E -- Groussin, O -- Gulkis, S -- Gurwell, M -- Hadamcik, E -- Hainaut, O -- Harker, D -- Harrington, D -- Harwit, M -- Hasegawa, S -- Hergenrother, C W -- Hirst, P -- Hodapp, K -- Honda, M -- Howell, E S -- Hutsemekers, D -- Iono, D -- Ip, W-H -- Jackson, W -- Jehin, E -- Jiang, Z J -- Jones, G H -- Jones, P A -- Kadono, T -- Kamath, U W -- Kaufl, H U -- Kasuga, T -- Kawakita, H -- Kelley, M S -- Kerber, F -- Kidger, M -- Kinoshita, D -- Knight, M -- Lara, L -- Larson, S M -- Lederer, S -- Lee, C-F -- Levasseur-Regourd, A C -- Li, J Y -- Li, Q-S -- Licandro, J -- Lin, Z-Y -- Lisse, C M -- LoCurto, G -- Lovell, A J -- Lowry, S C -- Lyke, J -- Lynch, D -- Ma, J -- Magee-Sauer, K -- Maheswar, G -- Manfroid, J -- Marco, O -- Martin, P -- Melnick, G -- Miller, S -- Miyata, T -- Moriarty-Schieven, G H -- Moskovitz, N -- Mueller, B E A -- Mumma, M J -- Muneer, S -- Neufeld, D A -- Ootsubo, T -- Osip, D -- Pandea, S K -- Pantin, E -- Paterno-Mahler, R -- Patten, B -- Penprase, B E -- Peck, A -- Petitas, G -- Pinilla-Alonso, N -- Pittichova, J -- Pompei, E -- Prabhu, T P -- Qi, C -- Rao, R -- Rauer, H -- Reitsema, H -- Rodgers, S D -- Rodriguez, P -- Ruane, R -- Ruch, G -- Rujopakarn, W -- Sahu, D K -- Sako, S -- Sakon, I -- Samarasinha, N -- Sarkissian, J M -- Saviane, I -- Schirmer, M -- Schultz, P -- Schulz, R -- Seitzer, P -- Sekiguchi, T -- Selman, F -- Serra-Ricart, M -- Sharp, R -- Snell, R L -- Snodgrass, C -- Stallard, T -- Stecklein, G -- Sterken, C -- Stuwe, J A -- Sugita, S -- Sumner, M -- Suntzeff, N -- Swaters, R -- Takakuwa, S -- Takato, N -- Thomas-Osip, J -- Thompson, E -- Tokunaga, A T -- Tozzi, G P -- Tran, H -- Troy, M -- Trujillo, C -- Van Cleve, J -- Vasundhara, R -- Vazquez, R -- Vilas, F -- Villanueva, G -- von Braun, K -- Vora, P -- Wainscoat, R J -- Walsh, K -- Watanabe, J -- Weaver, H A -- Weaver, W -- Weiler, M -- Weissman, P R -- Welsh, W F -- Wilner, D -- Wolk, S -- Womack, M -- Wooden, D -- Woodney, L M -- Woodward, C -- Wu, Z-Y -- Wu, J-H -- Yamashita, T -- Yang, B -- Yang, Y-B -- Yokogawa, S -- Zook, A C -- Zauderer, A -- Zhao, X -- Zhou, X -- Zucconi, J-M -- New York, N.Y. -- Science. 2005 Oct 14;310(5746):265-9. Epub 2005 Sep 8.〈br /〉〈span class="detail_caption"〉Author address: 〈/span〉Institute for Astronomy, University of Hawaii at Manoa, 2680 Woodlawn Drive, Honolulu, HI 96822, USA.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/16150977" target="_blank"〉PubMed〈/a〉
    Keywords: Cosmic Dust ; Jupiter ; *Meteoroids ; Organic Chemicals ; Photometry
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  • 18
    Publication Date: 2005-09-17
    Description: The impact cratering process on a comet is controversial but holds the key for interpreting observations of the Deep Impact collision with comet 9P/Tempel 1. Mid-infrared data from the Cooled Mid-Infrared Camera and Spectrometer (COMICS) of the Subaru Telescope indicate that the large-scale dust plume ejected by the impact contained a large mass (approximately 10(6) kilograms) of dust and formed two wings approximately +/-45 degrees from the symmetric center, both consistent with gravity as the primary control on the impact and its immediate aftermath. The dust distribution in the inner part of the plume, however, is inconsistent with a pure gravity control and implies that evaporation and expansion of volatiles accelerated dust.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Sugita, S -- Ootsubo, T -- Kadono, T -- Honda, M -- Sako, S -- Miyata, T -- Sakon, I -- Yamashita, T -- Kawakita, H -- Fujiwara, H -- Fujiyoshi, T -- Takato, N -- Fuse, T -- Watanabe, J -- Furusho, R -- Hasegawa, S -- Kasuga, T -- Sekiguchi, T -- Kinoshita, D -- Meech, K J -- Wooden, D H -- Ip, W H -- A'Hearn, M F -- New York, N.Y. -- Science. 2005 Oct 14;310(5746):274-8. Epub 2005 Sep 15.〈br /〉〈span class="detail_caption"〉Author address: 〈/span〉Department of Complexity Science and Engineering, University of Tokyo, Kashiwa, Chiba, Japan. sugita@k.u-tokyo.ac.jp〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/16166476" target="_blank"〉PubMed〈/a〉
    Keywords: Cosmic Dust ; Jupiter ; *Meteoroids ; Spectrophotometry, Infrared ; Volatilization
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  • 19
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    American Association for the Advancement of Science (AAAS)
    Publication Date: 1995-02-24
    Description: 〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Akiyama, M -- Kodama, K -- Mabuchi, K -- Ohara, J L -- Preston, D L -- Satoh, C -- Akahoshi, M -- Honda, T -- Soda, M -- New York, N.Y. -- Science. 1995 Feb 24;267(5201):1077.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/7855582" target="_blank"〉PubMed〈/a〉
    Keywords: Government Agencies ; Humans ; International Cooperation ; Japan ; *Nuclear Warfare ; *Radiation Injuries ; Survivors ; United States
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  • 20
    Publication Date: 1993-02-26
    Description: The effects of multiple phase transitions on mantle convection are investigated by numerical simulations that are based on three-dimensional models. These simulations show that cold sheets of mantle material collide at junctions, merge, and form a strong downflow that is stopped temporarily by the transition zone. The accumulated cold material gives rise to a strong gravitational instability that causes the cold mass to sink rapidly into the lower mantle. This process promotes a massive exchange between the lower and upper mantles and triggers a global instability in the adjacent plume system. This mechanism may be cyclic in nature and may be linked to the generation of superplumes.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Honda, S -- Yuen, D A -- Balachandar, S -- Reuteler, D -- New York, N.Y. -- Science. 1993 Feb 26;259(5099):1308-11.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/17732253" target="_blank"〉PubMed〈/a〉
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