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  • 1
    Monograph available for loan
    Monograph available for loan
    Berkeley [u.a.] : University of California Press
    Call number: AWI G1-95-0182b ; AWI G1-95-0182a
    Type of Medium: Monograph available for loan
    Pages: 372 S.
    ISBN: 0520040015
    Series Statement: Studies in Ecology 5
    Branch Library: AWI Library
    Branch Library: AWI Library
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  • 2
    Publication Date: 2013-02-13
    Description: The composition and prevalence of microorganisms in the middle-to-upper troposphere (8–15 km altitude) and their role in aerosol-cloud-precipitation interactions represent important, unresolved questions for biological and atmospheric science. In particular, airborne microorganisms above the oceans remain essentially uncharacterized, as most work to date is restricted to samples taken near the...
    Print ISSN: 0027-8424
    Electronic ISSN: 1091-6490
    Topics: Biology , Medicine , Natural Sciences in General
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  • 3
    Publication Date: 1997-01-03
    Description: The oriented peptide library technique was used to investigate the peptide-binding specificities of nine PDZ domains. Each PDZ domain selected peptides with hydrophobic residues at the carboxyl terminus. Individual PDZ domains selected unique optimal motifs defined primarily by the carboxyl terminal three to seven residues of the peptides. One family of PDZ domains, including those of the Discs Large protein, selected peptides with the consensus motif Glu-(Ser/Thr)-Xxx-(Val/Ile) (where Xxx represents any amino acid) at the carboxyl terminus. In contrast, another family of PDZ domains, including those of LIN-2, p55, and Tiam-1, selected peptides with hydrophobic or aromatic side chains at the carboxyl terminal three residues. On the basis of crystal structures of the PSD-95-3 PDZ domain, the specificities observed with the peptide library can be rationalized.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Songyang, Z -- Fanning, A S -- Fu, C -- Xu, J -- Marfatia, S M -- Chishti, A H -- Crompton, A -- Chan, A C -- Anderson, J M -- Cantley, L C -- CA66263/CA/NCI NIH HHS/ -- DK34989/DK/NIDDK NIH HHS/ -- R01 GM056203/GM/NIGMS NIH HHS/ -- New York, N.Y. -- Science. 1997 Jan 3;275(5296):73-7.〈br /〉〈span class="detail_caption"〉Author address: 〈/span〉Division of Signal Transduction, Beth Israel Hospital, and Department of Cell Biology, Harvard Medical School, Boston, MA 02115, USA.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/8974395" target="_blank"〉PubMed〈/a〉
    Keywords: Amino Acid Sequence ; Animals ; Binding Sites ; Crystallography, X-Ray ; Guanine Nucleotide Exchange Factors ; Guanylate Kinase ; Helminth Proteins/chemistry/metabolism ; Humans ; Kinesin/chemistry/metabolism ; Membrane Proteins/chemistry/metabolism ; Models, Molecular ; Myosins/chemistry/metabolism ; Nerve Tissue Proteins/chemistry/metabolism ; Nucleoside-Phosphate Kinase/chemistry/metabolism ; Peptide Library ; Peptides/chemistry/*metabolism ; Protein Structure, Secondary ; Protein Structure, Tertiary ; Protein Tyrosine Phosphatases/chemistry/metabolism ; Proteins/chemistry/*metabolism ; Sequence Homology, Amino Acid
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
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  • 4
    Publication Date: 2016-04-09
    Description: We present the discovery by the WASP-South survey of WASP-121 b, a new remarkable short-period transiting hot Jupiter. The planet has a mass of $1.183_{-0.062}^{+0.064}$ M Jup , a radius of 1.865 ± 0.044 R Jup , and transits every $1.274\,9255_{-0.000\,0025}^{+0.000\,0020}$ days an active F6-type main-sequence star ( V = 10.4, $1.353_{-0.079}^{+0.080}$ M , 1.458 ± 0.030 R , T eff = 6460 ± 140 K). A notable property of WASP-121 b is that its orbital semimajor axis is only ~1.15 times larger than its Roche limit, which suggests that the planet is close to tidal disruption. Furthermore, its large size and extreme irradiation (~7.1 10 9  erg s –1 cm –2 ) make it an excellent target for atmospheric studies via secondary eclipse observations. Using the TRAnsiting Planets and PlanetesImals Small Telescope, we indeed detect its emission in the z ' -band at better than ~4, the measured occultation depth being 603 ± 130 ppm. Finally, from a measurement of the Rossiter–McLaughlin effect with the CORALIE spectrograph, we infer a sky-projected spin-orbit angle of $257{^{\circ}_{.}} 8_{-5{^{\circ}_{.}} 5}^{+5{^{\circ}_{.}} 3}$ . This result may suggest a significant misalignment between the spin axis of the host star and the orbital plane of the planet. If confirmed, this high misalignment would favour a migration of the planet involving strong dynamical events with a third body.
    Print ISSN: 0035-8711
    Electronic ISSN: 1365-2966
    Topics: Physics
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  • 5
    Publication Date: 2013-10-11
    Description: Ecological and societal disruptions by modern climate change are critically determined by the time frame over which climates shift beyond historical analogues. Here we present a new index of the year when the projected mean climate of a given location moves to a state continuously outside the bounds of historical variability under alternative greenhouse gas emissions scenarios. Using 1860 to 2005 as the historical period, this index has a global mean of 2069 (+/-18 years s.d.) for near-surface air temperature under an emissions stabilization scenario and 2047 (+/-14 years s.d.) under a 'business-as-usual' scenario. Unprecedented climates will occur earliest in the tropics and among low-income countries, highlighting the vulnerability of global biodiversity and the limited governmental capacity to respond to the impacts of climate change. Our findings shed light on the urgency of mitigating greenhouse gas emissions if climates potentially harmful to biodiversity and society are to be prevented.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Mora, Camilo -- Frazier, Abby G -- Longman, Ryan J -- Dacks, Rachel S -- Walton, Maya M -- Tong, Eric J -- Sanchez, Joseph J -- Kaiser, Lauren R -- Stender, Yuko O -- Anderson, James M -- Ambrosino, Christine M -- Fernandez-Silva, Iria -- Giuseffi, Louise M -- Giambelluca, Thomas W -- England -- Nature. 2013 Oct 10;502(7470):183-7. doi: 10.1038/nature12540.〈br /〉〈span class="detail_caption"〉Author address: 〈/span〉Department of Geography, University of Hawai'i at Manoa, Honolulu, Hawai'i 96822, USA. cmora@hawaii.edu〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/24108050" target="_blank"〉PubMed〈/a〉
    Keywords: Animals ; Biodiversity ; *Computer Simulation ; *Global Warming ; Time
    Print ISSN: 0028-0836
    Electronic ISSN: 1476-4687
    Topics: Biology , Chemistry and Pharmacology , Medicine , Natural Sciences in General , Physics
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  • 6
    Publication Date: 2014-07-06
    Description: 〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Mora, Camilo -- Frazier, Abby G -- Longman, Ryan J -- Dacks, Rachel S -- Walton, Maya M -- Tong, Eric J -- Sanchez, Joseph J -- Kaiser, Lauren R -- Stender, Yuko O -- Anderson, James M -- Ambrosino, Christine M -- Fernandez-Silva, Iria -- Giuseffi, Louise M -- Giambelluca, Thomas W -- England -- Nature. 2014 Jul 3;511(7507):E5-6. doi: 10.1038/nature13524.〈br /〉〈span class="detail_caption"〉Author address: 〈/span〉Department of Geography, University of Hawai'i at Manoa, Honolulu, Hawaii 96822, USA. ; Department of Biology, University of Hawaii at Manoa, Honolulu, Hawaii 96822, USA. ; 1] Department of Biology, University of Hawaii at Manoa, Honolulu, Hawaii 96822, USA [2] Hawaii Institute of Marine Biology, University of Hawaii at Manoa, Kane'ohe, Hawaii 96744, USA. ; 1] Hawaii Institute of Marine Biology, University of Hawaii at Manoa, Kane'ohe, Hawaii 96744, USA [2] Department of Oceanography, University of Hawaii at Manoa, Honolulu, Hawaii 96822, USA. ; 1] Department of Geography, University of Hawai'i at Manoa, Honolulu, Hawaii 96822, USA [2] Hawaii Institute of Marine Biology, University of Hawaii at Manoa, Kane'ohe, Hawaii 96744, USA. ; 1] Hawaii Institute of Marine Biology, University of Hawaii at Manoa, Kane'ohe, Hawaii 96744, USA [2] Trans-disciplinary Organization for Subtropical Island Studies (TRO-SIS), University of the Ryukyus, Senbaru, Nishihara, Okinawa 903-0213, Japan.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/24990758" target="_blank"〉PubMed〈/a〉
    Keywords: Animals ; *Computer Simulation ; *Global Warming
    Print ISSN: 0028-0836
    Electronic ISSN: 1476-4687
    Topics: Biology , Chemistry and Pharmacology , Medicine , Natural Sciences in General , Physics
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  • 7
    Publication Date: 2016-03-26
    Description: 〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Collins, Francis S -- Anderson, James M -- Austin, Christopher P -- Battey, James F -- Birnbaum, Linda S -- Briggs, Josephine P -- Clayton, Janine A -- Cuthbert, Bruce -- Eisinger, Robert W -- Fauci, Anthony S -- Gallin, John I -- Gibbons, Gary H -- Glass, Roger I -- Gottesman, Michael M -- Gray, Patricia A -- Green, Eric D -- Greider, Franziska B -- Hodes, Richard -- Hudson, Kathy L -- Humphreys, Betsy -- Katz, Stephen I -- Koob, George F -- Koroshetz, Walter J -- Lauer, Michael S -- Lorsch, Jon R -- Lowy, Douglas R -- McGowan, John J -- Murray, David M -- Nakamura, Richard -- Norris, Andrea -- Perez-Stable, Eliseo J -- Pettigrew, Roderic I -- Riley, William T -- Rodgers, Griffin P -- Sieving, Paul A -- Somerman, Martha J -- Spong, Catherine Y -- Tabak, Lawrence A -- Volkow, Nora D -- Wilder, Elizabeth L -- New York, N.Y. -- Science. 2016 Mar 25;351(6280):1405. doi: 10.1126/science.351.6280.1405-a.〈br /〉〈span class="detail_caption"〉Author address: 〈/span〉Office of the Director, NIH, Bethesda, MD 20892, USA. collinsf@mail.nih.gov. ; Division of Program Coordination, Planning, and Strategic Initiatives, NIH, Bethesda, MD 20892, USA. ; National Center for Advancing Translational Science, NIH, Rockville, MD 20850, USA. ; National Institute on Deafness and Other Communication Disorders, NIH, Bethesda, MD 20892, USA. ; National Institute of Environmental Health Sciences, NIH, Research Triangle Park, NC 27709, USA. ; National Center for Complementary and Integrative Health, NIH, Bethesda, MD 20892, USA. ; Office of Research on Women's Health, NIH, Bethesda, MD 20892, USA. ; National Institute of Mental Health, NIH, Bethesda, MD 20892, USA. ; Office of AIDS Research, NIH, Bethesda, MD 20892, USA. ; National Institute of Allergy and Infectious Diseases, NIH, Bethesda, MD 20892, USA. ; Clinical Center, NIH, Bethesda, MD 20892, USA. ; National Heart, Lung, and Blood Institute, NIH, Bethesda, MD 20892, USA. ; Fogarty International Center, NIH, Bethesda, MD 20892, USA. ; Office of Intramural Research, NIH, Bethesda, MD 20892, USA. ; National Institute of Nursing Research, NIH, Bethesda, MD 20892, USA. ; National Human Genome Research Institute, NIH, Bethesda, MD 20892, USA. ; Office of Research Infrastructure Programs, NIH, Bethesda, MD 20892, USA. ; National Institute on Aging, NIH, Bethesda, MD 20892, USA. ; Office of the Director, NIH, Bethesda, MD 20892, USA. ; National Library of Medicine, NIH, Bethesda, MD 20892, USA. ; National Institute of Arthritis and Musculoskeletal and Skin Diseases, NIH, Bethesda, MD 20892, USA. ; National Institute on Alcohol Abuse and Alcoholism, NIH, Bethesda, MD 20892, USA. ; NINDS, NIH, Bethesda, MD 20892, USA. ; Office of Extramural Research, NIH, Bethesda, MD 20892, USA. ; National Institute of General Medical Sciences, NIH, Bethesda, MD 20892, USA. ; National Cancer Institute, NIH, Bethesda, MD 20892, USA. ; Office of Management, NIH, Bethesda, MD 20892, USA. ; Office of Disease Prevention, NIH, Bethesda, MD 20892, USA. ; Center for Scientific Review, NIH, Bethesda, MD 20892, USA. ; Center for Information Technology, NIH, Bethesda, MD 20892, USA. ; National Institute on Minority Health and Health Disparities, NIH, Bethesda, MD 20892, USA. ; National Institute of Biomedical Imaging and Bioengineering, NIH, Bethesda, MD 20892, USA. ; Office of Behavioral and Social Sciences Research, NIH, Bethesda, MD 20892, USA. ; National Institute of Diabetes and Digestive and Kidney Diseases, NIH, Bethesda, MD 20892, USA. ; National Eye Institute, NIH, Bethesda, MD 20892, USA. ; National Institute of Dental and Craniofacial Research, NIH, Bethesda, MD 20892, USA. ; Eunice Kennedy Shriver National Institute of Child Health and Human Development, NIH, Bethesda, MD 20892, USA. ; National Institute on Drug Abuse, NIH, Bethesda, MD 20892, USA. ; Office of Strategic Coordination, NIH, Bethesda, MD 20892, USA.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/27013720" target="_blank"〉PubMed〈/a〉
    Keywords: Animals ; Biomedical Research/*economics ; Humans ; National Institutes of Health (U.S.)/*economics
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
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  • 8
    Publication Date: 2013-06-05
    Description: Smith and Griffin (1) raise four concerns regarding our study of the microbiome of the upper troposphere (2). Sampling microbial cells in this environment remains technically challenging, but the concerns raised are not substantial for the reasons stated below. Our methods were adequate and our conclusions well supported by the...
    Keywords: Letters
    Print ISSN: 0027-8424
    Electronic ISSN: 1091-6490
    Topics: Biology , Medicine , Natural Sciences in General
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  • 9
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    Unknown
    American Association for the Advancement of Science (AAAS)
    Publication Date: 1979-12-21
    Description: Selenium concentrations in the serums of 17 acutely ill Legionnaires' disease patients were significantly lower than in their matching convalescent-phase serums. This trend was not observed in ten similarly paired samples of serum from control patients with pneumonia. There were no significant differences in the concentrations of nickel, copper, bromine, rubidium, lead, barium, or titanium in the serums of Legionnaires' disease and control patients.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Chen, J R -- Anderson, J M -- New York, N.Y. -- Science. 1979 Dec 21;206(4425):1426-7.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/505018" target="_blank"〉PubMed〈/a〉
    Keywords: Humans ; Legionnaires' Disease/*blood ; Metals/blood ; Nickel/blood ; Selenium/*blood
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
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  • 10
    Electronic Resource
    Electronic Resource
    s.l. : American Chemical Society
    Macromolecules 10 (1977), S. 352-356 
    ISSN: 1520-5835
    Source: ACS Legacy Archives
    Topics: Chemistry and Pharmacology , Physics
    Type of Medium: Electronic Resource
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