ALBERT

All Library Books, journals and Electronic Records Telegrafenberg

X
feed icon rss

Your email was sent successfully. Check your inbox.

An error occurred while sending the email. Please try again.

Proceed reservation?

Export
Filter
  • Articles  (1,697)
  • Polymer and Materials Science  (1,575)
  • Mice  (122)
  • 1975-1979  (1,697)
  • 1950-1954
  • 1940-1944
  • Process Engineering, Biotechnology, Nutrition Technology  (1,575)
  • Biology  (122)
  • History
Collection
  • Articles  (1,697)
Source
Keywords
Publisher
Years
Year
Journal
Topic
  • 1
    facet.materialart.
    Unknown
    Tumor location detected with radioactively labeled monoclonal antibody and external scintigraphy (1979)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1979-11-16
    Description: Murine teratocarcinomas were located in mice by external gamma-ray scintigraphy with an iodine-125-labeled monoclonal antibody specific to the tumors. The specificity of the method was increased by subtracting the radiation produced by an iodine-125-labeled indifferent monoclonal antibody of the same immunoglobulin class as the tumor-specific antibody.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Ballou, B -- Levine, G -- Hakala, T R -- Solter, D -- New York, N.Y. -- Science. 1979 Nov 16;206(4420):844-7.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/493985" target="_blank"〉PubMed〈/a〉
    Keywords: Animals ; Antibodies, Neoplasm ; Clone Cells/immunology ; Mice ; Neoplasms, Experimental/diagnosis/immunology ; Radionuclide Imaging/*methods ; Teratoma/*diagnosis/immunology
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
    Published by American Association for the Advancement of Science (AAAS)
    Location Call Number Expected Availability
    BibTip Others were also interested in ...
    PAPER CURRENT
  • 2
    facet.materialart.
    Unknown
    Obesity genes: beneficial effects in heterozygous mice (1979)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1979-02-16
    Description: The mouse mutant genes obese (ob) and diabetes (db) cause similar obesity-diabetes states in homozygotes. These obesity syndromes are characterized by a more efficient conversion of food to lipid and, once stored, a slower rate of catabolism on fasting. Heterozygous mice, either ob/+ or db/+, survived a prolonged fast significantly longer than normal homozygotes (+/+); this suggests that the heterozygotes exhibited increased metabolic efficiency, a feature normally associated with both homozygous mutants. The existence of this thriftiness trait, if manifested by heterozygous carriers in wild populations, would lend credence to the thrifty gene concept of diabetes. Beneficial effects of normally deleterious genes may have played a role in the development of diabetes-susceptible human populations, as well as having provided the survival advantage that has allowed both the development and successful establishment of species in desert and other less affluent regions.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Coleman, D L -- New York, N.Y. -- Science. 1979 Feb 16;203(4381):663-5.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/760211" target="_blank"〉PubMed〈/a〉
    Keywords: Animals ; Body Temperature Regulation ; Diabetes Mellitus, Experimental/*genetics/metabolism ; Fasting ; Glucose/metabolism ; Heterozygote ; Insulin/blood ; Mice ; Mice, Obese/*genetics
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
    Published by American Association for the Advancement of Science (AAAS)
    Location Call Number Expected Availability
    BibTip Others were also interested in ...
    PAPER CURRENT
  • 3
    facet.materialart.
    Unknown
    Enhanced 5-fluorouracil nucleotide formation after methotrexate administration: explanation for drug synergism (1979)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1979-09-14
    Description: Exposure of L1210 leukemia cells first to 0.1 to 100 micromolar methotrexate and then to 10 micromolar 5-fluorouracil produces a synergistic effect on the number of cells killed in culture. Methotrexate dose-related increases occur in the concentrations of intracellular 5-fluorouracil ribonucleotides and 5-fluoro-2'-deoxyuridylate and in the incorporation of 5-fluorouracil into RNA. These increases are correlated with increased concentrations of intracellular phosphoribosylpyrophosphate. It is proposed that the enhanced formation of ribonucleotides of 5-fluorouracil and the subsequent incorporation of these compounds into RNA in methotrexate-treated cells may account for synergism between these agents.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Cadman, E -- Heimer, R -- Davis, L -- New York, N.Y. -- Science. 1979 Sep 14;205(4411):1135-7.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/472732" target="_blank"〉PubMed〈/a〉
    Keywords: Animals ; Cells, Cultured ; Drug Administration Schedule ; Drug Synergism ; Fluorouracil/metabolism/*pharmacology ; Leukemia L1210 ; Methotrexate/*pharmacology ; Mice ; Phosphoribosyl Pyrophosphate/metabolism ; RNA, Neoplasm/metabolism ; Ribonucleotides/metabolism ; Thymidylate Synthase/metabolism
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
    Published by American Association for the Advancement of Science (AAAS)
    Location Call Number Expected Availability
    BibTip Others were also interested in ...
    PAPER CURRENT
  • 4
    facet.materialart.
    Unknown
    Seaweed dermatitis: structure of lyngbyatoxin A (1979)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1979-04-13
    Description: A highly inflammatory and vesicatory substance, lyngbyatoxin A, has been isolated from the lipid extract of a Hawaiian shallow-water variety of Lyngbya majuscula Gomont; its gross structure was determined from chemical and spectral data. Lyngbyatoxin A is closely related to teleocidin B, a poisonous substance associated with several strains of Streptomyces.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Cardellina, J H 2nd -- Marner, F J -- Moore, R E -- New York, N.Y. -- Science. 1979 Apr 13;204(4389):193-5.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/107586" target="_blank"〉PubMed〈/a〉
    Keywords: Alkaloids/*toxicity ; Animals ; *Cyanobacteria ; Dermatitis, Contact/*etiology ; *Dermotoxins ; Indoles/toxicity ; *Marine Toxins ; Mice
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
    Published by American Association for the Advancement of Science (AAAS)
    Location Call Number Expected Availability
    BibTip Others were also interested in ...
    PAPER CURRENT
  • 5
    facet.materialart.
    Unknown
    Cytidylate cyclase: possible artifacts in the methodology (1979)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1979-02-16
    Description: 〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Gaion, R M -- Krishna, G -- New York, N.Y. -- Science. 1979 Feb 16;203(4381):672-3.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/760214" target="_blank"〉PubMed〈/a〉
    Keywords: Animals ; Cytosine Nucleotides ; Liver/*enzymology ; Lyases/*metabolism ; Mice
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
    Published by American Association for the Advancement of Science (AAAS)
    Location Call Number Expected Availability
    BibTip Others were also interested in ...
    PAPER CURRENT
  • 6
    facet.materialart.
    Unknown
    Effect of beta-endorphin on calcium uptake in the brain (1979)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1979-10-05
    Description: The uptake of 45Ca2+ by nerve-ending fractions from brains of mice was inhibited in vitro by 10(-9)M concentrations of beta-endorphin and in mice injected intraventricularly with 7 picomoles of beta-endorphin. That the effect was a specific opiate agonist response of beta-endorphin was demonstrated by use of the opiate antagonist, naloxone, which reversed the action. A role for beta-endorphin in the regulation of calcium flux and neurotransmitter release should be considered.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Guerrero-Munoz, F -- de Lourdes Guerrero, M -- Way, E L -- Li, C H -- New York, N.Y. -- Science. 1979 Oct 5;206(4414):89-91.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/39340" target="_blank"〉PubMed〈/a〉
    Keywords: Animals ; Biological Transport/drug effects ; Calcium/*metabolism ; Dose-Response Relationship, Drug ; Drug Tolerance ; Endorphins/antagonists & inhibitors/*pharmacology ; Male ; Mice ; Naloxone/pharmacology ; Neurotransmitter Agents/metabolism ; Rats ; Synaptosomes/*drug effects/metabolism
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
    Published by American Association for the Advancement of Science (AAAS)
    Location Call Number Expected Availability
    BibTip Others were also interested in ...
    PAPER CURRENT
  • 7
    facet.materialart.
    Unknown
    Radioimmunoassay of the insulin receptor: a new probe of receptor structure and function (1979)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1979-02-09
    Description: A sensitive and specific radioimmunoassay for the insulin receptor has been developed employing receptor autoantibodies from the serum of a patient with insulin-resistant diabetes. The assay detects insulin binding sites at concentrations as low as 0.1 nanomolar; distinguishes between receptors originating from human placental membranes, human lymphoblastoid cells, and mouse liver membranes; and measures the receptor independently of its binding function. Down-regulation, or loss of binding after exposure to insulin, is associated with loss of immunoreactive receptor.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Harrison, L C -- Flier, J -- Itin, A -- Kahn, C R -- Roth, J -- New York, N.Y. -- Science. 1979 Feb 9;203(4380):544-7.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/83675" target="_blank"〉PubMed〈/a〉
    Keywords: Animals ; Antigen-Antibody Reactions ; Binding Sites ; Binding Sites, Antibody ; Epitopes ; Female ; Humans ; Liver/analysis ; Lymphocytes/analysis ; Mice ; Placenta/analysis ; Pregnancy ; Radioimmunoassay/methods ; Receptor, Insulin/analysis/*immunology ; Solubility
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
    Published by American Association for the Advancement of Science (AAAS)
    Location Call Number Expected Availability
    BibTip Others were also interested in ...
    PAPER CURRENT
  • 8
    facet.materialart.
    Unknown
    Genetic linkage of C3H/HeJ and BALB/c endogenous ecotropic C-type viruses to phosphoglucomutase-1 on chromosome 5 (1979)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1979-04-06
    Description: The genetic linkage of the endogenous C3H/HeJ C-type ecotropic virus to phosphoglucomutase-1 (0.28, recombinant fraction) on chromosome 5 was established by means of serological assays of backcrossed mice. With a combination of serological techniques and DNA-DNA hybridization the BALB/c endogenous ecotropic virus was shown to be either closely linked or allelic with the C3H/HeJ locus.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Ihle, J N -- Joseph, D R -- Domotor, J J Jr -- New York, N.Y. -- Science. 1979 Apr 6;204(4388):71-3.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/219476" target="_blank"〉PubMed〈/a〉
    Keywords: Alleles ; Animals ; Genes ; *Genes, Viral ; Genetic Linkage ; Leukemia Virus, Murine/genetics ; Mice ; Mice, Inbred BALB C/*microbiology ; Mice, Inbred C3H/*microbiology ; Mice, Inbred Strains/genetics ; Phenotype ; Phosphoglucomutase/*genetics ; Retroviridae/*genetics
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
    Published by American Association for the Advancement of Science (AAAS)
    Location Call Number Expected Availability
    BibTip Others were also interested in ...
    PAPER CURRENT
  • 9
    facet.materialart.
    Unknown
    Genetic mechanism accounting for precise immunoglobulin domain deletion in a variant of MPC 11 myeloma cells (1979)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1979-12-14
    Description: A variant of the MPC 11 cell line, M 311, produces a short immunoglobulin heavy chain. When compared with the parental gamma 2b heavy chain, M 311 was found to have a carboxyl terminal deletion comprising the CH3 domain. The COOH-terminal cyanogen bromide (CNBr) cleavage fragment of M 311 is identical to a corresponding segment ofa parental heavy chain CNBr fragment, with the exception of a substitution of asparagine for lysine at the COOH-terminal residue. This observation enabled prediction of both the parental DNA sequence in this region and the genetic mechanism which generated the variant, a frameshift followed by premature termination. This hypothesis is supported by studies of the DNA sequence of the MPC 11 gamma 2b constant region gene.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Kenter, A L -- Birshtein, B K -- R21 AI106328/AI/NIAID NIH HHS/ -- New York, N.Y. -- Science. 1979 Dec 14;206(4424):1307-9.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/117550" target="_blank"〉PubMed〈/a〉
    Keywords: Animals ; Cell Line ; Chromosome Deletion ; Genes ; Immunoglobulin G/*genetics ; Immunoglobulin gamma-Chains/genetics ; Macromolecular Substances ; Melphalan/pharmacology ; Mice ; Mutation ; Myeloma Proteins/*genetics ; Neoplasms, Experimental/genetics ; Peptide Chain Termination, Translational ; Plasmacytoma/genetics
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
    Published by American Association for the Advancement of Science (AAAS)
    Location Call Number Expected Availability
    BibTip Others were also interested in ...
    PAPER CURRENT
  • 10
    facet.materialart.
    Unknown
    Inosine may be an endogenous ligand for benzodiazepine receptors on cultured spinal neurons (1979)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1979-08-17
    Description: Mouse spinal neurons grown in tissue culture were used to study the membrane effects of the benzodiazepine flurazepam and the naturally occurring purine nucleoside inosine, which competes for benzodiazepine receptor sites in the central nervous system. Application of inosine elicited two types of transmitter-like membrane effects: a rapidly desensitizing excitatory response and a nondesensitizing inhibitory response. Flurazepam produced a similar excitatory response which showed cross-desensitization with the purine excitation. Flurazepam also blocked the inhibitory inosine response. The results provide electrophysiological evidence that an endogenous purine can activate two different conductances on spinal neurons and that flurazepam can activate one of the conductances and antagonize the other.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉MacDonald, J F -- Barker, J L -- Paul, S M -- Marangos, P J -- Skolnick, P -- New York, N.Y. -- Science. 1979 Aug 17;205(4407):715-7.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/37602" target="_blank"〉PubMed〈/a〉
    Keywords: Animals ; Benzodiazepines/*metabolism ; Cells, Cultured ; Electric Conductivity ; Flurazepam/antagonists & inhibitors ; Inosine/*metabolism/pharmacology ; Ligands ; Mice ; Neurotransmitter Agents/metabolism ; Receptors, Drug/*metabolism ; Receptors, Neurotransmitter/metabolism ; Spinal Cord/*metabolism
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
    Published by American Association for the Advancement of Science (AAAS)
    Location Call Number Expected Availability
    BibTip Others were also interested in ...
    PAPER CURRENT
  • 11
    facet.materialart.
    Unknown
    New drugs and the brain (1979)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1979-08-24
    Description: 〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Kolata, G B -- New York, N.Y. -- Science. 1979 Aug 24;205(4408):774-6.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/379998" target="_blank"〉PubMed〈/a〉
    Keywords: Animals ; France ; History, 20th Century ; Humans ; Mice ; Psychotropic Drugs/*history/metabolism/therapeutic use ; Rats ; Schizophrenia/drug therapy ; United States
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
    Published by American Association for the Advancement of Science (AAAS)
    Location Call Number Expected Availability
    BibTip Others were also interested in ...
    PAPER CURRENT
  • 12
    facet.materialart.
    Unknown
    Genetic mapping of the ecotropic murine leukemia virus-inducing locus of BALB/c mouse to chromosome 5 (1979)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1979-04-06
    Description: By means of an approach that combined the techniques of somatic cell genetics and Mendelian breeding studies, the inducibility locus, designated Cv, for ecotropic murine leukemia virus in BALB/c mice, was mapped to chromosome 5, 23 units from the locus for phosphoglucomutase-1, with gene order Cv-Pgm-1-Gus. This low-efficiency inducibility locus is therefore not allelic with the chromosome 7 loci previously described for two other mouse strains with high virus inducibility. These studies provide further evidence that endogenous ecotropic viruses represent viral genomes inserted at different chromosomal sites in the various mouse strains.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Kozak, C A -- Rowe, W P -- New York, N.Y. -- Science. 1979 Apr 6;204(4388):69-71.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/219475" target="_blank"〉PubMed〈/a〉
    Keywords: Animals ; Chromosome Mapping ; *Genes, Viral ; Genetic Linkage ; Hybrid Cells/microbiology ; Leukemia Virus, Murine/*genetics ; Mice ; Mice, Inbred BALB C/*microbiology ; Phosphoglucomutase/metabolism ; Virus Replication
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
    Published by American Association for the Advancement of Science (AAAS)
    Location Call Number Expected Availability
    BibTip Others were also interested in ...
    PAPER CURRENT
  • 13
    facet.materialart.
    Unknown
    Angiogenesis in the mouse cornea (1979)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1979-09-28
    Description: We have developed a method that permits analysis of neovascular responses in the mouse cornea. Using this method we have demonstrated that both allogeneic lymphocytes and a variety of tumors can induce angiogenesis, but that only the latter appear capable of eliciting secondary capillary sprouting.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Muthukkaruppan, V -- Auerbach, R -- New York, N.Y. -- Science. 1979 Sep 28;205(4413):1416-8.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/472760" target="_blank"〉PubMed〈/a〉
    Keywords: Animals ; Cornea/*blood supply ; In Vitro Techniques ; Mice ; Mice, Inbred Strains ; Microcirculation ; Neoplasms, Experimental/*blood supply
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
    Published by American Association for the Advancement of Science (AAAS)
    Location Call Number Expected Availability
    BibTip Others were also interested in ...
    PAPER CURRENT
  • 14
    facet.materialart.
    Unknown
    Drug safety: phenacetin (1979)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1979-07-13
    Description: 〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Macklin, A W -- Welch, R M -- Cuatrecasas, P -- New York, N.Y. -- Science. 1979 Jul 13;205(4402):144, 146, 148.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/451584" target="_blank"〉PubMed〈/a〉
    Keywords: Animals ; Carcinogens ; Liver Neoplasms/*chemically induced ; Mice ; Neoplasms, Experimental/chemically induced ; Phenacetin/*adverse effects/standards ; Rats
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
    Published by American Association for the Advancement of Science (AAAS)
    Location Call Number Expected Availability
    BibTip Others were also interested in ...
    PAPER CURRENT
  • 15
    facet.materialart.
    Unknown
    Inherited epilepsy: spike-wave and focal motor seizures in the mutant mouse tottering (1979)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1979-06-22
    Description: Mice with the mutant gene tottering (tg, chromosome 8, autosomal recessive) show, in adolescence, abnormal bursts of bilaterally synchronous spike waves as revealed in electrocorticograms recorded over long periods. The spike waves are accompanied by behavioral "absence" attacks and intermittent focal motor seizures showing somatotopic progression. Cerebral metabolic activity during seizures was assayed by autoradiography of brain sections from mice injected intravenously with 14C-labeled 2-deoxyglucose. Metabolic activity was increased bilaterally in selected brainstem structures. Spontaneous electrocorticographic and clinical seizures of this general pattern were recognized hitherto only in humans.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Noebels, J L -- Sidman, R L -- New York, N.Y. -- Science. 1979 Jun 22;204(4399):1334-6.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/572084" target="_blank"〉PubMed〈/a〉
    Keywords: Action Potentials ; Animals ; Behavior/*physiology ; Brain/growth & development/physiopathology ; Electrocardiography ; Epilepsy/*genetics/physiopathology ; Humans ; Mice ; Mice, Neurologic Mutants/genetics/*physiology ; Neural Pathways/physiopathology ; Seizures/physiopathology ; Stereotyped Behavior/*physiology
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
    Published by American Association for the Advancement of Science (AAAS)
    Location Call Number Expected Availability
    BibTip Others were also interested in ...
    PAPER CURRENT
  • 16
    facet.materialart.
    Unknown
    Methylation of mouse liver DNA studied by means of the restriction enzymes msp I and hpa II (1979)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1979-03-09
    Description: The restriction enzymes Hpa II and Msp I both recognize the sequence 5'-CCGG (C, cytosine; G, guanine). However, Hpa II cuts mouse liver DNA to fragments four times larger than does Msp I. The size of DNA cut by Msp I is close to that predicted from base composition and nearest neighbor analysis. The most probable explanation of these results is that in mouse the site 5'-CCGG is highly methylated.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Singer, J -- Roberts-Ems, J -- Riggs, A D -- New York, N.Y. -- Science. 1979 Mar 9;203(4384):1019-21.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/424726" target="_blank"〉PubMed〈/a〉
    Keywords: Animals ; DNA/*metabolism ; DNA (Cytosine-5-)-Methyltransferase/metabolism ; DNA Restriction Enzymes/metabolism ; Liver/metabolism ; Methylation ; Mice ; Molecular Weight ; Substrate Specificity
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
    Published by American Association for the Advancement of Science (AAAS)
    Location Call Number Expected Availability
    BibTip Others were also interested in ...
    PAPER CURRENT
  • 17
    facet.materialart.
    Unknown
    NCI bioassays yield a trail of blunders (1979)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1979-06-22
    Description: 〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Smith, R J -- New York, N.Y. -- Science. 1979 Jun 22;204(4399):1287-92.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/451534" target="_blank"〉PubMed〈/a〉
    Keywords: Animals ; Biological Assay/methods ; *Carcinogens ; Legislation as Topic ; Mice ; *National Institutes of Health (U.S.) ; Research Design/standards ; Research Support as Topic ; United States
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
    Published by American Association for the Advancement of Science (AAAS)
    Location Call Number Expected Availability
    BibTip Others were also interested in ...
    PAPER CURRENT
  • 18
    facet.materialart.
    Unknown
    Iron deficiency prevents liver toxicity of 2,3,7,8-tetrachlorodibenzo-p-dioxin (1979)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1979-04-20
    Description: The compound 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) causes hepatocellular damage and porphyria in C57B1/6J mice, among a wide range of toxic effects. We compared the effect of TCDD toxicity in iron-deficient mice with that in mice receiving a normal diet. Porphyria did not develop in the iron-deficient animals, and these animals were also protected from hepatocellular damage and certain other toxic effects of TCDD.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Sweeny, G D -- Jones, K G -- Cole, F M -- Basford, D -- Krestynski, F -- New York, N.Y. -- Science. 1979 Apr 20;204(4390):332-5.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/432648" target="_blank"〉PubMed〈/a〉
    Keywords: Animals ; Dioxins/*toxicity ; Enzyme Induction ; Iron/*deficiency ; Liver/pathology ; Mice ; Microsomes, Liver/enzymology ; Mixed Function Oxygenases/metabolism ; Porphyrias/*chemically induced ; Tetrachlorodibenzodioxin/*toxicity ; Uroporphyrinogen Decarboxylase/metabolism
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
    Published by American Association for the Advancement of Science (AAAS)
    Location Call Number Expected Availability
    BibTip Others were also interested in ...
    PAPER CURRENT
  • 19
    facet.materialart.
    Unknown
    Structure of the constant and 3' untranslated regions of the murine gamma 2b heavy chain messenger RNA (1979)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1979-12-14
    Description: The complete coding sequence for the constant region of the mouse gamma 2b immunoglobulin heavy chain and the 3' untranslated region has been determined. The coding portion of the sequence is 1008 nucleotides long (amino acid residues 114 to 449), and the 3' noncoding region contains 102 nucleotides preceeding the polyadenylate. An extra carboxyl-terminal lysine residue which had not been observed in the gamma 2b or other gamma subclass protein sequences occurs in the nucleotide sequence and is probably processed posttranslationally. A 17-nucleotide sequence occurs with slight variation twice in CH1 and once in CH2 domains in the same relative location but with different translational phase. This sequence may be the site of crossover in a gamma 2b . gamma 2a heavy chain variant, an indication of possible recombinational activity of some kind.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Tucker, P W -- Marcu, K B -- Slightom, J L -- Blattner, F R -- New York, N.Y. -- Science. 1979 Dec 14;206(4424):1299-303.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/117548" target="_blank"〉PubMed〈/a〉
    Keywords: Animals ; Base Sequence ; Biological Evolution ; Codon ; DNA, Recombinant ; Immunoglobulin Constant Regions/*genetics ; Immunoglobulin Heavy Chains/*genetics ; Immunoglobulin gamma-Chains/*genetics ; Immunoglobulins/*genetics ; Mice ; *Protein Biosynthesis ; RNA, Messenger/*genetics
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
    Published by American Association for the Advancement of Science (AAAS)
    Location Call Number Expected Availability
    BibTip Others were also interested in ...
    PAPER CURRENT
  • 20
    facet.materialart.
    Unknown
    Substance P: evidence for diverse roles in neuronal function from cultured mouse spinal neurons (1979)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1979-09-28
    Description: Mouse spinal neurons grown in tissue culture were used to examine the membrane mechanisms of action of the peptide substance P. Two functionally distinct actions were observed, one being a rapidly desensitizing excitation, and the other being a dose-dependent, reversible depression of excitatory responses to the putative amino acid neurotransmitter glutamate. These effects on excitability suggest that substance P may play more than one role in intercellular communication in the nervous system.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Vincent, J D -- Barker, J L -- New York, N.Y. -- Science. 1979 Sep 28;205(4413):1409-12.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/224464" target="_blank"〉PubMed〈/a〉
    Keywords: Animals ; Cell Communication ; Cells, Cultured ; Electric Conductivity ; Excitatory Amino Acid Antagonists ; Glutamates/pharmacology ; Membrane Potentials ; Mice ; Neural Inhibition ; Spinal Cord/cytology/*physiology ; Substance P/*physiology ; Synaptic Transmission
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
    Published by American Association for the Advancement of Science (AAAS)
    Location Call Number Expected Availability
    BibTip Others were also interested in ...
    PAPER CURRENT
  • 21
    facet.materialart.
    Unknown
    Hyperthermia and local anesthetics: potentiation of survival of tumor-bearing mice (1979)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1979-07-13
    Description: Lidocaine infusion of a CA755 mammary adenocarcinoma growing in the hind leg of BDF1 mice results in a significant increase in the animals' survival when combined with heating for 1 hour in a 43.5 degrees C water bath. This ability of local anesthetics to prolong survival following hyperthermia is consistent with the hypothesis that increases in membrane fluidity influence sensitivity to heat. In view of the extensive clinical experience with local anesthetics, the delay between clinical application and the observation that they potentiate the action of hyperthermia in animals may be reduced.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Yatvin, M B -- Clifton, K H -- Dennis, W H -- New York, N.Y. -- Science. 1979 Jul 13;205(4402):195-6.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/451588" target="_blank"〉PubMed〈/a〉
    Keywords: Adenocarcinoma/therapy ; Anesthetics, Local/*therapeutic use ; Animals ; Female ; *Hot Temperature ; Lidocaine/therapeutic use ; Mammary Neoplasms, Experimental/therapy ; Membrane Fluidity/drug effects ; Mice ; Neoplasms, Experimental/*therapy
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
    Published by American Association for the Advancement of Science (AAAS)
    Location Call Number Expected Availability
    BibTip Others were also interested in ...
    PAPER CURRENT
  • 22
    facet.materialart.
    Unknown
    Role of nuclear size in cell growth initiation (1979)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1979-06-22
    Description: Swiss 3T3 cells arrested in B0 (quiescent state) by reducing serum content of the medium all contain the same amount of DNA but vary in nuclear volume over approximately a twofold range. By use of flow microfluorimetry, scatterplots of nuclear volume versus DNA content were obtained in intervals after serum stimulation. The earliest cells to enter DNA synthesis were those with the largest nuclei, whereas cells with the smallest nuclei were among the latest. Regulation of cellular transit from G0 to the S phase was therefore, at least in part, deterministic, since all G0 cells did not have equal probabilities of entry into S at a given moment. All cells having the same nuclear volume did not initiate DNA synthesis at the same moment; therefore, factors other than nuclear volume must also influence this timing. Nuclear volume correlated with the maximum rate at which cells could enter S. The kinetic model of the cell cycle postulating a probabilistic event as solely responsible for entry into S thus appears too simple.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Yen, A -- Pardee, A B -- New York, N.Y. -- Science. 1979 Jun 22;204(4399):1315-7.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/451539" target="_blank"〉PubMed〈/a〉
    Keywords: Animals ; *Cell Cycle ; Cell Division ; Cell Nucleus/physiology/*ultrastructure ; Cells, Cultured/*physiology/ultrastructure ; Clone Cells/ultrastructure ; DNA/biosynthesis ; Mice
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
    Published by American Association for the Advancement of Science (AAAS)
    Location Call Number Expected Availability
    BibTip Others were also interested in ...
    PAPER CURRENT
  • 23
    facet.materialart.
    Unknown
    Sporozoite-induced malaria: therapeutic effects of glycolipids in liposomes (1979)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1979-09-14
    Description: Liposomes containing neutral glycolipids with a terminal glucose or galactose, when injected intravenously, prevented the appearance of erythrocytic forms of malaria (Plasmodium berghei) in mice previously injected with sporozoites. Inhibitory glycolipids included glucosyl, galactosyl, or lactosyl ceramide. Inhibition was not observed with liposomes containing ceramide, phosphocholine ceramide, sulfogalactosyl ceramide (sulfatide), or ganglioside GM1. Liposomes containing glycolipids did not inhibit infection transmitted by injecting blood containing erythrocytic stages of malaria. These results may have therapeutic implications in the treatment of malaria. Analysis of the mechanism of interference with the life cycle of malaria by liposomal glycolipids may yield information about the interactions of parasites with cellular membranes.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Alving, C R -- Schneider, I -- Swartz, G M Jr -- Steck, E A -- New York, N.Y. -- Science. 1979 Sep 14;205(4411):1142-4.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/382358" target="_blank"〉PubMed〈/a〉
    Keywords: Animals ; Ceramides/therapeutic use ; Erythrocytes/parasitology ; Glycolipids/*therapeutic use ; Liposomes/therapeutic use ; Liver/parasitology ; Malaria/parasitology/*therapy ; Mice ; Plasmodium berghei ; Structure-Activity Relationship
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
    Published by American Association for the Advancement of Science (AAAS)
    Location Call Number Expected Availability
    BibTip Others were also interested in ...
    PAPER CURRENT
  • 24
    facet.materialart.
    Unknown
    Chemical carcinogens (1979)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1979-02-16
    Description: 〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉New York, N.Y. -- Science. 1979 Feb 16;203(4381):602-3.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/760207" target="_blank"〉PubMed〈/a〉
    Keywords: Animals ; *Carcinogens/administration & dosage ; Dose-Response Relationship, Drug ; Mice ; Mutagens ; Neoplasms, Experimental/chemically induced ; Rats ; Vinyl Chloride/*toxicity ; Vinyl Compounds/*toxicity
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
    Published by American Association for the Advancement of Science (AAAS)
    Location Call Number Expected Availability
    BibTip Others were also interested in ...
    PAPER CURRENT
  • 25
    facet.materialart.
    Unknown
    Canine Babesia new to North America (1979)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1979-06-29
    Description: A domestic dog residing in New England suffered a fatal febrile illness caused by a Babesia infection. The morphology of these intraerythrocytic protozoa and the range of hosts that could be infected experimentally suggested that the parasite was B. gibsoni. Although this tick-bourne disease is enzootic in wild and domestic Canidae in Africa and Asia, it appears to be new to the Americas.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Anderson, J F -- Magnarelli, L A -- Donner, C S -- Spielman, A -- Piesman, J -- New York, N.Y. -- Science. 1979 Jun 29;204(4400):1431-2.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/451574" target="_blank"〉PubMed〈/a〉
    Keywords: Animals ; Arthropod Vectors ; Babesia/classification/cytology ; Babesiosis/epidemiology/*parasitology/transmission ; Cricetinae ; Dog Diseases/*parasitology ; Dogs ; Erythrocytes/parasitology ; Mice ; United States
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
    Published by American Association for the Advancement of Science (AAAS)
    Location Call Number Expected Availability
    BibTip Others were also interested in ...
    PAPER CURRENT
  • 26
    facet.materialart.
    Unknown
    Molecular cloning of polyoma virus DNA in Escherichia coli: lambda phage vector system (1979)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1979-03-02
    Description: The biological activity of recombinant phage and recombinant phage DNA containing monomeric or dimeric polyoma DNA inserts was examined in mice and cultured mouse cells. Recombinant preparations containing a single copy of viral DNA were invariably noninfectious; molecules containing a dimeric polyoma DNA insert were at least seven orders of magnitude less infectious than polyoma virions after parenteral inoculation. No infection was detected with any recombinant preparation after oral administration.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Chan, H W -- Israel, M A -- Garon, C F -- Rowe, W P -- Martin, M A -- New York, N.Y. -- Science. 1979 Mar 2;203(4383):887-92.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/217088" target="_blank"〉PubMed〈/a〉
    Keywords: Animals ; Cells, Cultured ; Coliphages/*genetics ; DNA Restriction Enzymes/metabolism ; *DNA, Recombinant ; DNA, Viral/genetics ; Escherichia coli/*genetics ; Mice ; Polyomavirus/*genetics ; Risk ; Tumor Virus Infections/*genetics ; Virus Replication
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
    Published by American Association for the Advancement of Science (AAAS)
    Location Call Number Expected Availability
    BibTip Others were also interested in ...
    PAPER CURRENT
  • 27
    facet.materialart.
    Unknown
    Permeability of the cell-to-cell membrane channels in mammalian cell juncton (1979)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1979-07-27
    Description: The channels in the junctions of various mammalian cell types--primary cultures and lines--were probed with a series of linear fluorescent amino acid and peptide molecules of different size and charge. Permeability is limited by probe size and electronegativity, these two factors apparently being related reciprocally. In respect to both factors, mammalian junctional channels are more restrictive than insect channels; hence the mammalian channels are narrower, more polar, or both. The channels of the various mammalian cell types differed slightly from each other; in some types the serum of the culture medium affected the channel permeability.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Flagg-Newton, J -- Simpson, I -- Loewenstein, W R -- New York, N.Y. -- Science. 1979 Jul 27;205(4404):404-7.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/377490" target="_blank"〉PubMed〈/a〉
    Keywords: Animals ; Cell Line ; Cell Membrane/physiology ; *Cell Membrane Permeability ; Cells, Cultured ; Cricetinae ; Fluorescent Antibody Technique ; Kidney ; Mice ; Mice, Inbred BALB C ; Species Specificity
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
    Published by American Association for the Advancement of Science (AAAS)
    Location Call Number Expected Availability
    BibTip Others were also interested in ...
    PAPER CURRENT
  • 28
    facet.materialart.
    Unknown
    Sequence of the cloned gene for the constant region of murine gamma 2b immunoglobulin heavy chain (1979)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1979-12-14
    Description: The complete nucleotide sequence of the gamma 2b constant region gene cloned from BALB/c liver DNA is reported. The sequence of approximately 1870 base pairs includes the 5' flanking, 3' untranslated, and 3' flanking regions and three introns. The C gamma 2b coding region is divided by these introns into four segments corresponding to the homology domains and hinge region of the protein. The introns separating the hinge from the CH2 domain and the CH2 from the CH3 domain are small (106 and 119 base pairs). A larger intervening sequence of 314 base pairs separates the CH1 and hinge regions. The stretch of DNA comprising this large intron plus the hinge shows a strong homology with the other CH domains.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Tucker, P W -- Marcu, K B -- Newell, N -- Richards, J -- Blattner, F R -- New York, N.Y. -- Science. 1979 Dec 14;206(4424):1303-6.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/117549" target="_blank"〉PubMed〈/a〉
    Keywords: Animals ; Base Sequence ; Biological Evolution ; DNA, Recombinant ; *Genes ; Immunoglobulin Constant Regions/*genetics ; Immunoglobulin Heavy Chains/*genetics ; Immunoglobulin gamma-Chains/*genetics ; Immunoglobulins/*genetics ; Liver ; Mice ; Mice, Inbred BALB C ; Nucleic Acid Precursors/genetics ; RNA, Messenger/genetics ; Transcription, Genetic
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
    Published by American Association for the Advancement of Science (AAAS)
    Location Call Number Expected Availability
    BibTip Others were also interested in ...
    PAPER CURRENT
  • 29
    facet.materialart.
    Unknown
    Phenacetin studies (1979)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1979-11-09
    Description: 〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Vaught, J B -- King, C M -- New York, N.Y. -- Science. 1979 Nov 9;206(4419):637, 639.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/493967" target="_blank"〉PubMed〈/a〉
    Keywords: Acute Kidney Injury/chemically induced ; Animals ; Biotransformation ; *Carcinogens ; Humans ; Kidney Neoplasms/chemically induced ; Mice ; Mutation ; Phenacetin/*adverse effects/metabolism
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
    Published by American Association for the Advancement of Science (AAAS)
    Location Call Number Expected Availability
    BibTip Others were also interested in ...
    PAPER CURRENT
  • 30
    facet.materialart.
    Unknown
    "Sontaneous" neoplastic transformation in vitro: a form of foreign body (smooth surface) tumorigenesis (1979)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1979-04-13
    Description: Explants of subcutaneous connective tissue from adult BALB/c mice into plastic petri dishes were serially subcultured and tested for tumorigenicity in two ways: by the subcutaneous implantation of cells attached to plastic plates (1 by 5 by 10 millimeters), and by the subcutaneous injection of cells suspended in saline. Cells grown in vitro for 18 or more days before being implanted attached to a plastic plate (2.4 x 10(4) to 3.4 x 10(5) cells per plate) formed tumors after 24 to 79 weeks. The latent period before tumor appearance correlated inversely with the time spent by the cells in tissue culture. Cells inoculated in saline suspension (10 to 100 times the above number per plate) did not form tumors until after 84 days in vitro; plates alone did not induce tumor formation within more than 1 1/2 years of implantation. The tumors arising from the plate-attached cells were transplantable without plates and histologically appeared to be undifferentiated sarcomas. It is well established that smooth-surfaced foreign bodies, regardless of their chemical composition, will produce sarcomas when transplanted subcutaneously in rodents. We interpret our data, particularly the decrease in tumor latent period with time spent in tissue culture, as indicating that a smooth surface was acting as a carcinogen first in vitro (the surface of the tissue culture dish) and then in vivo (the surface of the plastic plate).〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Boone, C W -- Takeichi, N -- Eaton, S D -- Paranjpe, M -- New York, N.Y. -- Science. 1979 Apr 13;204(4389):177-9.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/373119" target="_blank"〉PubMed〈/a〉
    Keywords: Animals ; *Cell Transformation, Neoplastic/pathology ; Cells, Cultured ; Connective Tissue/pathology ; Female ; Foreign-Body Reaction/*complications ; Mice ; Neoplasms, Experimental/*etiology ; *Plastics ; Sarcoma, Experimental/etiology ; Time Factors
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
    Published by American Association for the Advancement of Science (AAAS)
    Location Call Number Expected Availability
    BibTip Others were also interested in ...
    PAPER CURRENT
  • 31
    facet.materialart.
    Unknown
    Release of luteinizing hormone in male mice during exposure to females: habituation of the response (1979)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1979-11-30
    Description: Male mice release luteinizing hormone when exposed for a short time to a female. In this experiment, multiple blood samples were withdrawn by atrial cannulas from tethered males during either continuous or intermittent exposure to nonreceptive females. After an immediate, transient release of luteinizing hormone, continuous exposure to the same female was accompanied by only random, spontaneous elevations in plasma levels of this hormone. Successive presentations of the same female at 2-hour intervals elicited gradually diminishing luteinizing hormone responses. Exposing such unresponsive males to novel, diestrous females, however, dramatically stimulated their release of the hormone. These results demonstrate habituation of a socially induced, neuroendocrine response involving reproductive hormones.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Coquelin, A -- Bronson, F H -- New York, N.Y. -- Science. 1979 Nov 30;206(4422):1099-101.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/573924" target="_blank"〉PubMed〈/a〉
    Keywords: Animals ; Arousal/physiology ; Diestrus ; Female ; Habituation, Psychophysiologic/*physiology ; Luteinizing Hormone/*metabolism ; Male ; Mice ; Pregnancy ; Sexual Behavior, Animal/physiology
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
    Published by American Association for the Advancement of Science (AAAS)
    Location Call Number Expected Availability
    BibTip Others were also interested in ...
    PAPER CURRENT
  • 32
    facet.materialart.
    Unknown
    A synthetic pentapeptide with biological activity characteristic of the thymic hormone thymopoietin (1979)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1979-06-22
    Description: The pentapeptide arginyl-lysyl-aspartyl-valyl-tyrosine, corresponding to amino acid residues 32--36 in thymopoietin, was synthesized. In vitro, this pentapeptide induced the differentiation of murine prothymocytes to thymocytes and inhibited differentiative induction of cells of the B lineage. This combination of actions is presently unique to the parent molecule thymopoietin. In vivo, the pentapeptide reduced the high numbers of autologous rosette-forming cells normally present in the spleens of athymic mice; this also is a property of thymopoietin. These results suggest that this readily synthesized pentapeptide corresponds to an active site of thymopoietin and might serve as a therapeutic substitute for thymopoietin.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Goldstein, G -- Scheid, M P -- Boyse, E A -- Schlesinger, D H -- Van Wauwe, J -- New York, N.Y. -- Science. 1979 Jun 22;204(4399):1309-10.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/451537" target="_blank"〉PubMed〈/a〉
    Keywords: Amino Acid Sequence ; Animals ; Antigens, Surface/analysis ; Cell Differentiation/drug effects ; Complement System Proteins ; Isoantigens/analysis ; Lymphocytes/cytology/*immunology ; Mice ; Mice, Nude/immunology ; Oligopeptides/chemical synthesis/*pharmacology ; Receptors, Drug/analysis ; Structure-Activity Relationship ; Thymopoietins/*pharmacology ; Thymus Hormones/*pharmacology
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
    Published by American Association for the Advancement of Science (AAAS)
    Location Call Number Expected Availability
    BibTip Others were also interested in ...
    PAPER CURRENT
  • 33
    facet.materialart.
    Unknown
    Opiate (Enkephalin) receptors of neuroblastoma cells: occurrence in clusters on the cell surface (1979)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1979-11-30
    Description: A bioactive, fluorescent derivative of enkephalin, Tyr-D-Ala-Gly-Phe-Leu-Lys-rhodamine, was used to determine the distribution of opiate receptors in living neuroblastoma cells. The receptors appeared in clusters on the cell surface, and no internalization was detected. No specific fluorescence or clusters were observed in the presence of [D-Ala2, Leu5]enkephalin or at 4 degrees C, and the clusters were much reduced under ionic conditions (that is, with 100 millimolars sodium) that specifically decrease the binding of opiate agonists.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Hazum, E -- Chang, K J -- Cuatrecasas, P -- New York, N.Y. -- Science. 1979 Nov 30;206(4422):1077-9.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/227058" target="_blank"〉PubMed〈/a〉
    Keywords: Animals ; Cell Line ; Endorphins/*metabolism ; Enkephalins/*metabolism ; Mice ; Microscopy, Fluorescence ; Neoplasms, Experimental/metabolism ; Neuroblastoma/*metabolism ; Receptors, Opioid/*metabolism ; Synaptic Membranes/metabolism
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
    Published by American Association for the Advancement of Science (AAAS)
    Location Call Number Expected Availability
    BibTip Others were also interested in ...
    PAPER CURRENT
  • 34
    facet.materialart.
    Unknown
    Monoclonal antibodies defining distinctive human T cell surface antigens (1979)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1979-10-19
    Description: Three novel nonoclonal antibodies (designed OKT1, OKT3, and OKT4) were generated against surface determinants of human peripheral T cells. Both OKT1 and OKT3 reacted with all human peripheral T cells and 5 to 10 percent of thymocytes but differed in their reactivities with T cel- lines. By contrast, OKT4 reacted with 55 percent of human peripheral T cells and 80 percent of thymocyted in that they did not react with normal B cells, null cells, monocytes, or granulocytes.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Kung, P -- Goldstein, G -- Reinherz, E L -- Schlossman, S F -- New York, N.Y. -- Science. 1979 Oct 19;206(4416):347-9.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/314668" target="_blank"〉PubMed〈/a〉
    Keywords: Animals ; Antibody Specificity ; Antigens, Surface/*analysis ; Cells, Cultured/immunology ; Clone Cells/immunology ; Humans ; Leukemia, Experimental/immunology ; Mice ; Plasmacytoma/immunology ; T-Lymphocytes/*immunology
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
    Published by American Association for the Advancement of Science (AAAS)
    Location Call Number Expected Availability
    BibTip Others were also interested in ...
    PAPER CURRENT
  • 35
    facet.materialart.
    Unknown
    Nuclear transcripts of mouse heavy chain immunoglobulin genes contain only the expressed class of C-region sequences (1979)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1979-06-08
    Description: In plasmacytoma cells producing IgG, IgA, or IgM immunoglobulin heavy chains, the large precursors of the heavy chain messenger RNA's contain nucleotide sequences that specify only the expressed class of constant region. This indicates that the switch from one class of heavy chain to another during B cell ontogeny does not occur by altered processing of a complex gene transcript.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Marcu, K B -- Schibler, U -- Perry, R P -- New York, N.Y. -- Science. 1979 Jun 8;204(4397):1087-8.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/109919" target="_blank"〉PubMed〈/a〉
    Keywords: Animals ; Base Sequence ; Cell Line ; Cell Nucleus/metabolism ; Immunoglobulin Constant Regions/*genetics ; Immunoglobulin Heavy Chains/*genetics ; Immunoglobulins/*genetics ; Mice ; Myeloma Proteins/*genetics ; Neoplasms, Experimental/immunology ; Nucleic Acid Precursors/genetics ; Plasmacytoma/immunology ; Poly A/metabolism ; RNA, Heterogeneous Nuclear/genetics ; *Transcription, Genetic
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
    Published by American Association for the Advancement of Science (AAAS)
    Location Call Number Expected Availability
    BibTip Others were also interested in ...
    PAPER CURRENT
  • 36
    facet.materialart.
    Unknown
    Novel activation mechanism for the promutagenic herbicide diallate (1979)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1979-09-07
    Description: The potent bacterial mutagen 2-chloroacrolein is formed from the carcinogenic herbicide S-2,3-dichloroallyl diisopropylthiocarbamate (diallate) on incubation with hepatic microsomal monooxygenases or on reaction with m-chloroperbenzoic acid. A proposed activation mechanism for this promutagen involves sulfoxidation followed by [2,3] sigmatropic rearrangement and 1,2-elimination reactions. A portion of the highly reactive intermediate, diallate sulfoxide (proximate mutagens), is attacked by glutathione in a reaction which competes with its transformation to the ultimate mutagen, 2-chloroacrolein.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Schuphan, I -- Rosen, J D -- Casida, J E -- New York, N.Y. -- Science. 1979 Sep 7;205(4410):1013-5.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/472719" target="_blank"〉PubMed〈/a〉
    Keywords: Acrolein/pharmacology ; Animals ; Biotransformation ; Herbicides/*metabolism/pharmacology ; Mice ; Microsomes, Liver/metabolism ; *Mutagens ; Mutation/drug effects ; Rats ; Thiocarbamates/*metabolism/pharmacology
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
    Published by American Association for the Advancement of Science (AAAS)
    Location Call Number Expected Availability
    BibTip Others were also interested in ...
    PAPER CURRENT
  • 37
    facet.materialart.
    Unknown
    A regulatory locus for mouse beta-glucuronidase induction, Gur, controls messenger RNA activity (1979)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1979-02-09
    Description: A regulatory locus in a higher organism has been shown to control a specific messenger RNA activity. The Gur locus in mice regulates the production of kidney beta-glucuronidase messenger RNA activity after induction of the beta-glucuronidase structural gene, Gus, by testosterone. beta-Glucuronidase messenger RNA was assayed by its ability to direct the synthesis of catalytically active murine beta-glucuronidase in Xenopus oocytes.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Paigen, K -- Labarca, C -- Watson, G -- New York, N.Y. -- Science. 1979 Feb 9;203(4380):554-6.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/760204" target="_blank"〉PubMed〈/a〉
    Keywords: Animals ; Enzyme Induction/drug effects ; Female ; Genes ; *Genes, Regulator ; Genetic Linkage ; Glucuronidase/*genetics ; Hot Temperature ; Kidney/*enzymology ; Mice ; Oocytes/metabolism ; RNA, Messenger/*genetics ; Testosterone/pharmacology ; Xenopus
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
    Published by American Association for the Advancement of Science (AAAS)
    Location Call Number Expected Availability
    BibTip Others were also interested in ...
    PAPER CURRENT
  • 38
    facet.materialart.
    Unknown
    Stress and coping factors influence tumor growth (1979)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1979-08-03
    Description: Growth of syngeneic P815 mastocytoma in DBA/2J male mice was evaluated as a result of various stress regimens. A single session of inescapable shock resulted in earlier tumor appearance, exaggeration of tumor size, and decreased survival time in recipient animals. Escapable shock had no such effects. The effects of the inescapable shock were mitigated if mice received long-term shock treatment.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Sklar, L S -- Anisman, H -- New York, N.Y. -- Science. 1979 Aug 3;205(4405):513-5.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/109924" target="_blank"〉PubMed〈/a〉
    Keywords: Animals ; Electroshock ; Humans ; Male ; Mast-Cell Sarcoma/complications/*physiopathology ; Mice ; Neoplasms, Experimental/complications/physiopathology ; Stress, Psychological/complications/*physiopathology
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
    Published by American Association for the Advancement of Science (AAAS)
    Location Call Number Expected Availability
    BibTip Others were also interested in ...
    PAPER CURRENT
  • 39
    facet.materialart.
    Unknown
    Morphine-naloxone interactions: a role for nonspecific morphine excitatory effects in withdrawal (1979)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1979-09-28
    Description: The opiate antagonist naloxone precipitates withdrawal when given either 15 minutes after or 1 minute before a single injection of morphine in drug-naive mice. We propose that withdrawal signs arise from a synergistic mixture of excitatory influences that are direct (agonistic action on nonspecific opiate receptors) and indirect (sensory and affective disorders, stress, hormonal and neurotransmitter dysfunction, and so forth). The predominant effects during precipitated withdrawal are assumed to be direct, whereas during abstinence in tolerant animals they are indirect.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Stevens, D R -- Klemm, W R -- New York, N.Y. -- Science. 1979 Sep 28;205(4413):1379-8.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/224462" target="_blank"〉PubMed〈/a〉
    Keywords: Animals ; Behavior, Animal/physiology ; Dose-Response Relationship, Drug ; Drug Interactions ; Drug Tolerance ; Female ; Humans ; Mice ; Morphine/*pharmacology ; Naloxone/*pharmacology ; Receptors, Opioid/*drug effects ; Stereotyped Behavior/physiology ; Substance Withdrawal Syndrome/*physiopathology
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
    Published by American Association for the Advancement of Science (AAAS)
    Location Call Number Expected Availability
    BibTip Others were also interested in ...
    PAPER CURRENT
  • 40
    facet.materialart.
    Unknown
    Simultaneous production of Q and R bands after staining with chromomycin A3 or olivomycin (1979)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1979-04-06
    Description: Human and mouse chromosomes, stained with either chromomycin A3 or olivomycin, which bind preferentially to G - C-rich DNA (where G is guanosine and C is cytosine), exhibit a Q or a reverse banding pattern, depending on the wavelength used for excitation. The two complementary banding patterns can be observed in the same metaphase simply by changing the combination of excitation filters. These data suggest, therefore, that in addition to base composition, other factors are involved in the production of chromosome banding by chromomycin A3 and olivomycin.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Prantera, G -- Bonaccorsi, S -- Pimpinelli, S -- New York, N.Y. -- Science. 1979 Apr 6;204(4388):79-80.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/86207" target="_blank"〉PubMed〈/a〉
    Keywords: Animals ; Base Sequence ; Cells, Cultured ; Centromere/ultrastructure ; *Chromomycins ; Chromosomes/*ultrastructure ; *Dna ; Fluorescent Dyes ; Humans ; Mice ; *Olivomycins ; Staining and Labeling
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
    Published by American Association for the Advancement of Science (AAAS)
    Location Call Number Expected Availability
    BibTip Others were also interested in ...
    PAPER CURRENT
  • 41
    facet.materialart.
    Unknown
    Rank order of sarcoma susceptibility among mouse strains reverses with low concentrations of carcinogen (1979)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1979-04-20
    Description: Ten mouse strains in which aryl hydrocarbon hydroxylase can be induced, or F1 hybrids of these strains, were ranked according to their sarcoma susceptibility when exposed to a high concentration (5 percent) of the chemical carcinogen 3-methylcholanthrene. This rank order was reversed when the concentration of 3-methylcholanthrene was reduced to 0.05 percent.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Prehn, L M -- Lawler, E M -- New York, N.Y. -- Science. 1979 Apr 20;204(4390):309-10.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/432644" target="_blank"〉PubMed〈/a〉
    Keywords: Animals ; Aryl Hydrocarbon Hydroxylases/genetics/metabolism ; Dose-Response Relationship, Drug ; Dose-Response Relationship, Immunologic ; Female ; Genes ; Male ; *Methylcholanthrene ; Mice ; Mice, Inbred Strains/*physiology ; Sarcoma, Experimental/*chemically induced/immunology
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
    Published by American Association for the Advancement of Science (AAAS)
    Location Call Number Expected Availability
    BibTip Others were also interested in ...
    PAPER CURRENT
  • 42
    facet.materialart.
    Unknown
    Exercise during development induces an increase in Purkinje cell dendritic tree size (1979)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1979-10-12
    Description: Mice allowed to exercise during the late postnatal period had Purkinje cells with larger dendritic trees and greater numbers of spines than littermates whose physical activity was severly restricted. These changes in Purkinje cells were accompanied by a selective reduction in the thickness of the cerebellar molecular layer. The data provide evidence for cerebellar plasticity during late development and demonstrate that physical activity can modify the development of Purkinje cell dendrites.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Pysh, J J -- Weiss, G M -- New York, N.Y. -- Science. 1979 Oct 12;206(4415):230-2.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/482938" target="_blank"〉PubMed〈/a〉
    Keywords: Animals ; Behavior, Animal/physiology ; Cell Differentiation ; Cerebellar Cortex/growth & development ; Cerebellum/*growth & development ; Dendrites/ultrastructure ; Female ; Male ; Mice ; Motor Activity/physiology ; Physical Exertion ; Purkinje Cells/*cytology
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
    Published by American Association for the Advancement of Science (AAAS)
    Location Call Number Expected Availability
    BibTip Others were also interested in ...
    PAPER CURRENT
  • 43
    facet.materialart.
    Unknown
    Differential competition with cytotoxic agents: an approach to selectivity in cancer chemotherapy (1979)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1979-11-30
    Description: An approach to increasing the selectivity of cancer chemotherapeutic agents is presented in which noncytotoxic competitive substrates are used to discern the differences in structural requirements for transport of cytotoxic agents between tumor cells and a sensitive host tissue, the hematopoietic precursor cells of the bone marrow. Examples are given for two such systems, one responsible for the transport of nucleosides and another for the transport of amino acids. Cytidine is twice as effective in reducing the toxicity of showdomycin for murine bone marrow cells in culture as it is for murine L1210 leukemia cella. Conversely, homoleucine is twice as effective in reducing the toxicity of melphalan for L1210 cells as it is for bone marrow cells. These observations can serve as a basis for the development of bone marrow protective agents and for the design of cytotoxic agents that may be preferentially transported into tumor cells.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Rabinowitz, M -- Uehara, Y -- Vistica, D T -- New York, N.Y. -- Science. 1979 Nov 30;206(4422):1085-7.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/493993" target="_blank"〉PubMed〈/a〉
    Keywords: Animals ; Antibiotics, Antineoplastic/*metabolism ; Biological Transport ; Bone Marrow/drug effects ; Leukemia L1210/drug therapy ; Melphalan/metabolism/therapeutic use ; Mice ; Neoplasms/*drug therapy ; Showdomycin/*metabolism/therapeutic use ; Structure-Activity Relationship
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
    Published by American Association for the Advancement of Science (AAAS)
    Location Call Number Expected Availability
    BibTip Others were also interested in ...
    PAPER CURRENT
  • 44
    facet.materialart.
    Unknown
    6-Hydroxydopamine potentiates acute herpes simplex virus infection of the superior cervical ganglion in mice (1979)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1979-08-03
    Description: Treatment of mice with 6-hydroxydopamine increased herpes simplex virus replication in the superior cervical ganglion while it decreased the subsequent prevalence of latent infection. Preganglionic neurectomy failed to block this effect. These observations suggest that intrinsic neural events modify the outcome of viral infections of the nervous system.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Price, R W -- New York, N.Y. -- Science. 1979 Aug 3;205(4405):518-20.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/221984" target="_blank"〉PubMed〈/a〉
    Keywords: Animals ; Ascorbic Acid/pharmacology ; Eye Diseases/immunology ; Female ; Ganglia, Autonomic/drug effects/*microbiology ; Herpes Simplex/immunology ; Hydroxydopamines/*pharmacology ; Immunity ; Mice ; Mice, Inbred BALB C ; Simplexvirus/drug effects/immunology/*pathogenicity
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
    Published by American Association for the Advancement of Science (AAAS)
    Location Call Number Expected Availability
    BibTip Others were also interested in ...
    PAPER CURRENT
  • 45
    facet.materialart.
    Unknown
    ACTH and vasopressin treatments immediately after a defeat increase future submissiveness in male mice (1979)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1979-06-22
    Description: Male mice were given a single injection of either adrenocorticotropic hormone (ACTH) or lysine vasopressin immediately after a defeat in an encounter with an aggressive male mouse. The defeated mice were tested for submissiveness at either 24 hours, 48 hours, or 7 days after the initial encounter. Both hormone treatments increased future submissiveness, although the time courses of the effects were different: The effects of ACTH disappeared after 48 hours, whereas those of vasopressin persisted for 7 days. These results suggest that changes in peptide hormone levels following naturally stressful experiences can affect the memory of those experiences, as expressed in future adaptive responses.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Roche, K E -- Leshner, A I -- New York, N.Y. -- Science. 1979 Jun 22;204(4399):1343-4.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/221973" target="_blank"〉PubMed〈/a〉
    Keywords: Adrenocorticotropic Hormone/*pharmacology ; Aggression/*drug effects ; Animals ; Behavior, Animal/*drug effects ; Humans ; Lypressin/*pharmacology ; Male ; Mice ; Stress, Psychological/physiopathology
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
    Published by American Association for the Advancement of Science (AAAS)
    Location Call Number Expected Availability
    BibTip Others were also interested in ...
    PAPER CURRENT
  • 46
    facet.materialart.
    Unknown
    Thyroid hormone influence on the susceptibility of mice to audiogenic seizures (1979)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1979-08-10
    Description: Serum thyroxine levels peak earlier and are significantly higher in audiogenic seizure-susceptible DBA/2J mice than in seizure-resistant C57BL/6J mice during early postnatal life. The seizure susceptibility of DBA/2J mice is suppressed by administration of an antithyroid drug or by radiothyroidectomy, while the seizure susceptibility of C57BL/6J mice is enhanced by treatment with excess thyroxine.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Seyfried, T N -- Glaser, G H -- Yu, R K -- New York, N.Y. -- Science. 1979 Aug 10;205(4406):598-600.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/451624" target="_blank"〉PubMed〈/a〉
    Keywords: *Acoustic Stimulation ; Animals ; Hyperthyroidism/blood ; Hypothyroidism/blood ; Mice ; Mice, Inbred Strains ; Propylthiouracil ; Seizures/*blood ; Thyroxine/*blood/pharmacology
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
    Published by American Association for the Advancement of Science (AAAS)
    Location Call Number Expected Availability
    BibTip Others were also interested in ...
    PAPER CURRENT
  • 47
    facet.materialart.
    Unknown
    Cholecystokinin in the brains of obese and nonobese mice (1979)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1979-01-05
    Description: Extracts of the cerebral cortes of genetically obese (ob/ob) mice with hyperphagia contain 0.05 +/- 0.02 microgram (mean +/- standard error) of cholecystokinin octapeptide equivalent per gram of wet weight compared to 0.15 +/- 0.01 microgram per gram for their nonobese littermates and 0.20 +/- 0.01 microgram per gram for normal LAF1 mice. These findings are suggestive of a causal relation between the diminished brain immunoreactive cholecystokinin content and the unrestrained appetite of the obese mice.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Straus, E -- Yalow, R S -- New York, N.Y. -- Science. 1979 Jan 5;203(4375):68-9.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/758680" target="_blank"〉PubMed〈/a〉
    Keywords: Animals ; Brain/*metabolism ; Cholecystokinin/*metabolism ; Mice ; Mice, Obese/*metabolism ; Satiation/physiology
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
    Published by American Association for the Advancement of Science (AAAS)
    Location Call Number Expected Availability
    BibTip Others were also interested in ...
    PAPER CURRENT
  • 48
    facet.materialart.
    Unknown
    Thyroxine increases nerve growth factor concentration in adult mouse brain (1979)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1979-04-27
    Description: The effects of thyroxine and propylthiouracil on nerve growth factor concentrations in cerebral cortex, cerebellum, and brainstem of adult male mice were assessed by using a sensitive radioimmunoassay for the beta-subunit of mouse nerve growth factor. Thyroxine administration significantly increased the concentration of nerve growth factor in all three brain areas compared to control values, whereas propylthiouracil was without effect. These results suggest that thyroid hormones stimulate nerve growth factor synthesis in the mature central nervous system, and raise the possibility that the influence of thyroid hormones on central nervous system development might be mediated or influenced by nerve growth factor.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Walker, P -- Weichsel, M E Jr -- Fisher, D A -- Guo, S M -- New York, N.Y. -- Science. 1979 Apr 27;204(4391):427-9.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/441732" target="_blank"〉PubMed〈/a〉
    Keywords: Animals ; Brain/*metabolism ; Brain Stem/metabolism ; Cerebellum/metabolism ; Cerebral Cortex/metabolism ; Mice ; Microtubules/metabolism ; Nerve Growth Factors/*metabolism ; Propylthiouracil/pharmacology ; Thyroxine/*pharmacology
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
    Published by American Association for the Advancement of Science (AAAS)
    Location Call Number Expected Availability
    BibTip Others were also interested in ...
    PAPER CURRENT
  • 49
    facet.materialart.
    Unknown
    Carcinogenicity of phenacetin (1979)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1979-04-13
    Description: 〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Tomatis, L -- New York, N.Y. -- Science. 1979 Apr 13;204(4389):129-30.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/432634" target="_blank"〉PubMed〈/a〉
    Keywords: Animals ; *Carcinogens ; Mice ; Neoplasms/*chemically induced ; Phenacetin/*toxicity ; Rats
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
    Published by American Association for the Advancement of Science (AAAS)
    Location Call Number Expected Availability
    BibTip Others were also interested in ...
    PAPER CURRENT
  • 50
    facet.materialart.
    Unknown
    GABA receptors in clonal cell lines: a model for study of benzodiazepine action at molecular level (1979)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1979-08-24
    Description: A "recptor unit" for gamma-aminobutyric acid (GABA), which includes brainlike receptor binding sites for tritium-labeled GABA and benzodiazepines (diazepam, clonazepam, and flunitrazepam) and a thermostable endogenous protein (GABA modulin) that inhibits both GABA and benzodiazepine binding, has been demonstrated in membranes prepared from NB2a neuroblastoma and C6 glioma clonal cell lines. In these cells, as in brain, diazepam (1 micromolar) prevents the effect of GABA modulin, and in turn GABA (0.oma and, to a lesser extent, the glioma cells represent a suitable model to study the interactions and the sequence of membrane and intracellular events triggered by the stimulation of benzodiazepine and GABA receptors.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Baraldi, M -- Guidotti, A -- Schwartz, J P -- Costa, E -- New York, N.Y. -- Science. 1979 Aug 24;205(4408):821-3.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/462192" target="_blank"〉PubMed〈/a〉
    Keywords: Animals ; Benzodiazepines/*metabolism ; Brain/*metabolism ; Cell Line ; Clonazepam/metabolism ; Clone Cells/metabolism ; Diazepam/metabolism/pharmacology ; Flunitrazepam/metabolism ; Membrane Proteins/pharmacology ; Mice ; Nerve Tissue Proteins/pharmacology ; Rats ; Receptors, Drug/*metabolism ; gamma-Aminobutyric Acid/*metabolism
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
    Published by American Association for the Advancement of Science (AAAS)
    Location Call Number Expected Availability
    BibTip Others were also interested in ...
    PAPER CURRENT
  • 51
    facet.materialart.
    Unknown
    How to assess cancer risks (1979)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1979-05-25
    Description: 〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Carter, L J -- New York, N.Y. -- Science. 1979 May 25;204(4395):811, 813, 815-6.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/441737" target="_blank"〉PubMed〈/a〉
    Keywords: Animals ; Government Agencies ; Humans ; Mice ; Neoplasms/*chemically induced ; Rats ; Risk ; United States
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
    Published by American Association for the Advancement of Science (AAAS)
    Location Call Number Expected Availability
    BibTip Others were also interested in ...
    PAPER CURRENT
  • 52
    facet.materialart.
    Unknown
    Perinatal exposure to cannabinoids alters male reproductive function in mice (1979)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1979-09-28
    Description: Oral administration of delta 9-tetrahydrocannabinol or cannabinol to female mice late in pregnancy and during early lactation alters body weight regulation and pituitary-gonadal function and suppresses adult copulatory activity in their male offspring. These findings suggest that both psychoactive and nonpsychoactive constituents of marihuana can affect the development of male reproductive functions in mice.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Dalterio, S -- Bartke, A -- New York, N.Y. -- Science. 1979 Sep 28;205(4413):1420-2.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/472762" target="_blank"〉PubMed〈/a〉
    Keywords: Animals ; Animals, Newborn ; Body Weight/drug effects ; Cannabinoids/*pharmacology ; Cannabinol/*pharmacology ; Copulation/drug effects ; Dronabinol/*pharmacology ; Male ; Mice ; Organ Size/drug effects ; Pituitary Hormones/blood ; Sex Differentiation/*drug effects ; Sexual Behavior, Animal/*drug effects ; Sexual Maturation/drug effects ; Testis/anatomy & histology ; Testosterone/blood
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
    Published by American Association for the Advancement of Science (AAAS)
    Location Call Number Expected Availability
    BibTip Others were also interested in ...
    PAPER CURRENT
  • 53
    facet.materialart.
    Unknown
    Molecular cloning of polyoma virus DNA in Escherichia coli: plasmid vector system (1979)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1979-03-02
    Description: A series of recombinant plasmids containing polyoma virus (PY) DNA were constructed, and their biological activity was evaluated in mice and in cultured mouse cells. While all of the recombinants studied contain the complete, potentially infectious viral DNA, in no case was the intact recombinant PY-plasmid DNA, or live Escherichia coli containing the recombinant plasmids, capable of inducing PY infection of mice, either by feeding or by parenteral injection.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Israel, M A -- Chan, H W -- Rowe, W P -- Martin, M A -- New York, N.Y. -- Science. 1979 Mar 2;203(4383):883-7.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/217087" target="_blank"〉PubMed〈/a〉
    Keywords: Animals ; Cells, Cultured ; Chromosome Mapping ; *DNA, Recombinant ; DNA, Viral/genetics ; Escherichia coli/*genetics ; Mice ; *Plasmids ; Polyomavirus/*genetics ; Transcription, Genetic ; Tumor Virus Infections/*genetics ; Virus Replication
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
    Published by American Association for the Advancement of Science (AAAS)
    Location Call Number Expected Availability
    BibTip Others were also interested in ...
    PAPER CURRENT
  • 54
    facet.materialart.
    Unknown
    Human and mouse hypoxanthine-guanine phosphoribosyltransferase: dimers and tetramers (1979)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1979-01-12
    Description: Human and mouse hypoxanthine-guanine phosphoribosyltransferase subunits combine to form an active heteropolymer. Dimers form the basic subunit structure of the enzymes, yet the dimers can readily associate to form tetramers. The equilibrium between dimers and tetramers is significantly influenced by the ionic strength of the enzyme solvent.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Johnson, G G -- Eisenberg, L R -- Migeon, B R -- New York, N.Y. -- Science. 1979 Jan 12;203(4376):174-6.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/569362" target="_blank"〉PubMed〈/a〉
    Keywords: Animals ; Cell Line ; Female ; Genetic Linkage ; Humans ; Hybrid Cells/enzymology ; *Hypoxanthine Phosphoribosyltransferase/genetics ; Macromolecular Substances ; Mice ; Molecular Weight ; Protein Conformation ; X Chromosome
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
    Published by American Association for the Advancement of Science (AAAS)
    Location Call Number Expected Availability
    BibTip Others were also interested in ...
    PAPER CURRENT
  • 55
    facet.materialart.
    Unknown
    Liposomes and local hyperthermia: selective delivery of methotrexate to heated tumors (1979)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1979-04-13
    Description: Liposomes with phase transitions a few degrees above physiological temperature delivered more than four times as much methotrexate to murine tumors heated to 42 degrees C as to unheated control tumors. Most of the accumulated drug appeared to be intracellular and bound to dihydrofolate reductase, the enzyme blocked by methotrexate in its role as an antineoplastic agent.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Weinstein, J N -- Magin, R L -- Yatvin, M B -- Zaharko, D S -- New York, N.Y. -- Science. 1979 Apr 13;204(4389):188-91.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/432641" target="_blank"〉PubMed〈/a〉
    Keywords: Animals ; *Hot Temperature ; Liposomes/*therapeutic use ; Male ; Metabolic Clearance Rate ; Methotrexate/*administration & dosage/metabolism ; Mice ; Neoplasms, Experimental/*drug therapy ; Phospholipids ; Structure-Activity Relationship
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
    Published by American Association for the Advancement of Science (AAAS)
    Location Call Number Expected Availability
    BibTip Others were also interested in ...
    PAPER CURRENT
  • 56
    facet.materialart.
    Unknown
    Embryonic rodent brain contains estrogen receptors (1979)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1979-05-04
    Description: Estradiol-binding proteins with the properties of putative estrogen receptors are present in cytosol extracts of embryonic mouse hypothalamus and other brain regions. These embryonic estrogen receptors are adultlike in their high affinity and limited capacity for estradiol, sensitivity to diethylstilbestrol, ability to adhere to DNA, and behavior during DNA-cellulose affinity chromatography. As early as 4 days before birth, mouse hypothalamus has approximately 40 percent of the adult concentration of hypothalamic estrogen receptors with these properties. These observations raise the possibility that embryonic rodent brain has the biochemical potential to respond to sex hormones and that the critical period of brain sexual differentiation could be initiated prenatally.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Vito, C C -- Fox, T O -- New York, N.Y. -- Science. 1979 May 4;204(4392):517-9.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/432656" target="_blank"〉PubMed〈/a〉
    Keywords: Age Factors ; Animals ; Binding Sites ; Brain/*embryology ; Chromatography, Affinity ; Cytosol/metabolism ; Hypothalamus/embryology ; Mice ; Receptors, Estrogen/*metabolism ; Sexual Maturation
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
    Published by American Association for the Advancement of Science (AAAS)
    Location Call Number Expected Availability
    BibTip Others were also interested in ...
    PAPER CURRENT
  • 57
    Electronic Resource
    Electronic Resource
    Osteomalacia and altered magnesium metabolism in the X-linked hypophosphatemic mouse (1979)
    Springer
    Calcified tissue international 27 (1979), S. 19-26 
    Details
    ISSN: 1432-0827
    Keywords: Bone diseases ; Familial hypophosphatemia ; Magnesium ; Mice ; Phosphorus
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine , Physics
    Notes: Summary A new genetic mutant in mice,Hyp, has been proposed as a model for the human disease X-linked hypophosphatemia (the most common form of vitamin D-resistant rickets). The gene is X-linked, dominant, and produces reduced renal tubular reabsorption of phosphate, hypophosphatemia, and dwarfism. Our goal was to evaluate the skeletal changes histologically and to measure chemically the prominant blood and bone minerals to judge the suitability of this mutant as a model for the human disease. Thirteen-week-old hemizygousHyp male mice were compared with their normal littermate controls. TheHyp mice were hypocalcemic, hypophosphatemic, hypermagnesemic, and had elevated plasma alkaline phosphatase. The femur ash weighed less than half the normal ash weight but had a normal Ca:P ratio. The ash composition was high in %Na and K but low in %Mg. The mandibular incisor ash was also low in %Mg. Histologically the femur showed wide osteoid borders and wide epiphyseal plate. Microradiography revealed reduced bone density and enlarged osteocyte lacunae. Skeletal muscle samples, although smaller in theHyp mice, showed no striking alternations in inorganic or total phosphate content, dry weight (as % wet weight), or extracellular fluid space. TheHyp gene in mice seems to produce a condition similar to that of X-linked hypophosphatemia in humans.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF02441156
    Location Call Number Expected Availability
    BibTip Others were also interested in ...
    Paper (German National Licenses)
    Fulltext
  • 58
    Electronic Resource
    Electronic Resource
    Pleomorphic C-type virus particles in bone tissue of strain 101 mice and (C3H × 101)F1 hybrids (1979)
    Springer
    Calcified tissue international 28 (1979), S. 259-262 
    Details
    ISSN: 1432-0827
    Keywords: C-type virus particles ; Bone tissue ; Mice
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine , Physics
    Notes: Summary The proximal tibial metaphysis of apparently healthy strain 101 mice, 3–4 weeks old, and (C3H×101)F1 hybrids, 3–48 weeks old, was studied by electron microscopy. Budding, immature, and mature C-type virus particles were found within trabecular bone tissue of 3 of 8 strain 101 and 4 of 12 (C3H×101)F1 mice. The particles were most common in lacunae of aging osteocytes and were only occasionally associated with osteoblasts. Although the morphology of budding and immature particles appeared to be identical with that of typical C-type viruses, most of the mature forms of particles showed atypical structure and size. The electron-dense core was very large and not clearly defined, measuring approximately 70–130 nm in diameter. This diffuse core sometimes completely filled the space within the envelope of the particles. The diameters of the pleomorphic mature C-type particles ranged from approximately 90 to 150 nm. The possible association between the production of pleomorphic C-type virus particles by bone cells and spontaneous osteomagenesis in 101 and (C3H × 101)F1 mice is discussed.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF02441245
    Location Call Number Expected Availability
    BibTip Others were also interested in ...
    Paper (German National Licenses)
    Fulltext
  • 59
    Electronic Resource
    Electronic Resource
    Effect of reciprocal crossing of selected lines of mice (1979)
    Springer
    Theoretical and applied genetics 54 (1979), S. 169-175 
    Details
    ISSN: 1432-2242
    Keywords: Mice ; Reciprocal crossing of lines ; Accumulated response to selection free of inbreeding
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology
    Notes: Summary Mass selection of mice was conducted in populations of various size for 16 generations. Each selected population (E) corresponded to an analogous unselected population (C). The experiment was conducted in three replicates. After the 16th generation the replicates of the selected and control lines were crossed. Reciprocal crossing within the control lines gave better results than reciprocal crossing of the selected lines, despite the fact that the selected mice were characterised by a higher inbreeding coefficient. Larger effects were also obtained when crossing smaller rather than larger populations. This result is understandable since the animals from the smaller populations were characterised by higher inbreeding coefficients. The effect of heterosis was higher upon crossing the control lines rather than the selected ones and this caused a decreased the response to selection in almost all the traits investigated.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00263047
    Location Call Number Expected Availability
    BibTip Others were also interested in ...
    Paper (German National Licenses)
    Fulltext
  • 60
    Electronic Resource
    Electronic Resource
    Fisher's reticulate mating system for immigration into an improved stock (1979)
    Springer
    Theoretical and applied genetics 55 (1979), S. 279-284 
    Details
    ISSN: 1432-2242
    Keywords: Mating system ; Selection ; Mice
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology
    Notes: Summary A reticulate mating system is described which was designed by the late R.A. Fisher to permit the introduction of new genetic variability into an improved stock by immigration. Analysis of part of a long-term experiment to alter the degree of dominance of the mutant Sd in mice using the system demonstrates a rapid response. Its applicability to stocks of animals of economic value is considered.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00265366
    Location Call Number Expected Availability
    BibTip Others were also interested in ...
    Paper (German National Licenses)
    Fulltext
  • 61
    Electronic Resource
    Electronic Resource
    Environmental maternal influences on body composition in mice selected for body weight (1979)
    Springer
    Theoretical and applied genetics 55 (1979), S. 209-223 
    Details
    ISSN: 1432-2242
    Keywords: Maternal effects ; Body composition ; Selection ; Growth ; Mice
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology
    Notes: Summary The effect of the postnatal maternal environment, simulated by rearing mice in litters of three, six or nine, on body weight and body composition was investigated in three lines of mice differing widely in growth rate. The lines were selected for high (H6) and low (L6) 6-week body weight while the control line was maintained by random selection. Body weight and weights and percentages of ether extract, water, ash and protein at 21, 42, 63 and 84 days were recorded. With few exceptions, there were positive correlated responses to selection in body weight and in weights of body components. At 21 and 42 days the correlated responses were larger in L6 mice than in H6 mice. Body weight and weights of body components were larger for mice reared in litters of three than for those reared in litters of nine. Also, mice reared in litters of six were intermediate in body weight and weights of some of the body components between those reared in litters of three and nine. Differences in body weight and weights of body components due to postnatal maternal environment were small by comparison with differences due to genetic line. There were significant line by maternal environment interactions in body weight at 21 days and in ether extract weight at 21 and 63 days. Line and maternal environment differences in percentages of body components did not follow any consistent trend. The results for percentages of body components were further complicated by line x maternal environment interactions. In general, both line and postnatal maternal environmental differences in percentages of body components diminished with age.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00268115
    Location Call Number Expected Availability
    BibTip Others were also interested in ...
    Paper (German National Licenses)
    Fulltext
  • 62
    Electronic Resource
    Electronic Resource
    The effects of selection for different combinations of weights at two ages on the growth curve of mice (1979)
    Springer
    Theoretical and applied genetics 55 (1979), S. 57-64 
    Details
    ISSN: 1432-2242
    Keywords: Mice ; Selection ; Growth curve
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology
    Notes: Summary The weights of mice in lines selected for different combinations of high and low body weights at 5 and at 10 weeks of age were recorded from 3 to 21 weeks of age. The average growth curve for each line was computed using the Gompertz function. The growth curves of lines selected for high or low weight at a single age (ST lines) showed large differences in estimates of mature size and small differences in estimates of maturing rate, i.e. of the relative rate of growth to maturity. The growth curves of lines selected by independent culling for divergent combinations of deviations of opposite sign in 5- and 10-week weights (ICL lines) showed little difference in estimates of mature size and a large difference in estimates of maturing rate. The growth curves of lines selected by index for divergence in 5-week weight with no change in 10-week-weight or for divergence in 10-week-weight with no change in 5-week weight showed large differences in estimates of mature size and large differences in estimates of the maturing rate. The relationship between mature size and maturing rate was affected in different ways by the three types of selection.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00285190
    Location Call Number Expected Availability
    BibTip Others were also interested in ...
    Paper (German National Licenses)
    Fulltext
  • 63
    Electronic Resource
    Electronic Resource
    Long bone growth during prolonged intermittent corticosteroid treatment and subsequent rehabilitation (1979)
    Springer
    Cell & tissue research 201 (1979), S. 51-62 
    Details
    ISSN: 1432-0878
    Keywords: Glucocorticoids ; Bone growth retardation ; Chondrocytes ; Rehabilitation ; Mice
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Notes: Summary Immature A/J mice were treated for up to 7 weeks with intermittent doses of triamcinolone hexacetonide and were thereafter allowed to recover for 7 weeks. Qualitative and quantitative morphological measurements were performed on the epiphyseal cartilage plate and diaphyseal bone of the humerus. By the third injection significant structural changes were noted in the cartilaginous tissue followed by a complete cessation of bone growth. The hormonal inhibitory effect on long bone growth lasted throughout the experimental period. However, at the end of the recovery period the length of the humerus was 96% of the normal. In contrast, the humeral width at midshaft and the width of its medullary cavity revealed slower recovery, achieving only 80% of the control values. Following rehabilitation, the growth of experimental epiphyseal plates exceeded that of nontreated animals as their width and the number of hypertrophic chondrocytes were 131% and 125% of their controls respectively. Thus, in A/J mice (a highly susceptible inbred strain of mice) intermittent (every four days) administration of a long-acting corticosteroid hormone arrested endochondral and periosteal bone formation; the former, however, underwent full recovery following the termination of the hormonal treatment.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00238047
    Location Call Number Expected Availability
    BibTip Others were also interested in ...
    Paper (German National Licenses)
    Fulltext
  • 64
    Electronic Resource
    Electronic Resource
    Apparate für die Destillation, Rektifikation, Sorption, Permeation und ExtraktionBerichterstatter: Dr. Ing. R. Schmidt und Dipl.-Ing. Rosemarie Berger, BASF Aktiengesellschaft, Postfach, 6700 Ludwigshafen/Rh. (1979)
    Weinheim : Wiley-Blackwell
    Chemie Ingenieur Technik - CIT 51 (1979), S. 1151-1158 
    Details
    ISSN: 0009-286X
    Keywords: Chemistry ; Polymer and Materials Science
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology , Process Engineering, Biotechnology, Nutrition Technology
    Additional Material: 7 Ill.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/cite.330511203
    Location Call Number Expected Availability
    BibTip Others were also interested in ...
    Paper (German National Licenses)
    Fulltext
  • 65
    Electronic Resource
    Electronic Resource
    Apparate und Maschinen für die Hochdruck-TechnikBerichterstatter: Dipl.-Ing. H. Wendt, BASF Aktiengesellschaft, D-6700 Ludwigshafen/Rh. (1979)
    Weinheim : Wiley-Blackwell
    Chemie Ingenieur Technik - CIT 51 (1979), S. 1184-1190 
    Details
    ISSN: 0009-286X
    Keywords: Chemistry ; Polymer and Materials Science
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology , Process Engineering, Biotechnology, Nutrition Technology
    Additional Material: 7 Ill.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/cite.330511207
    Location Call Number Expected Availability
    BibTip Others were also interested in ...
    Paper (German National Licenses)
    Fulltext
  • 66
    Electronic Resource
    Electronic Resource
    WerkstoffprüfungBerichterstatter: Dipl.-Phys. W. Siehr, Staatliche Materialprüfungsanstalt, Abt. Kunststoffe, Grafenstr. 2, 6100 Darmstadt. (1979)
    Weinheim : Wiley-Blackwell
    Chemie Ingenieur Technik - CIT 51 (1979), S. 1213-1215 
    Details
    ISSN: 0009-286X
    Keywords: Chemistry ; Polymer and Materials Science
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology , Process Engineering, Biotechnology, Nutrition Technology
    Additional Material: 6 Ill.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/cite.330511211
    Location Call Number Expected Availability
    BibTip Others were also interested in ...
    Paper (German National Licenses)
    Fulltext
  • 67
    Electronic Resource
    Electronic Resource
    Ultrafiltration bei konzentrationsabhängigen Stoffwerten (1979)
    Weinheim : Wiley-Blackwell
    Chemie Ingenieur Technik - CIT 51 (1979), S. 1241-1241 
    Details
    ISSN: 0009-286X
    Keywords: Ultrafiltration ; konzentrationsabhängige Stoffwerte ; makromolekulare Stoffe ; Konzentrationspolarisation ; Chemistry ; Polymer and Materials Science
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology , Process Engineering, Biotechnology, Nutrition Technology
    Additional Material: 2 Ill.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/cite.330511218
    Location Call Number Expected Availability
    BibTip Others were also interested in ...
    Paper (German National Licenses)
    Fulltext
  • 68
    Electronic Resource
    Electronic Resource
    Gleichgewicht bei der Adsorption mehrerer Komponenten aus der GasphaseVortrag anläßlich der Sitzung des GVC-Fachausschusses „Trocknungstechnik“ am 26. April 1979 in Eindhoven. (1979)
    Weinheim : Wiley-Blackwell
    Chemie Ingenieur Technik - CIT 51 (1979), S. 1245-1245 
    Details
    ISSN: 0009-286X
    Keywords: Adsorption ; Mehrkomponentengleichgewicht ; Phasengleichgewicht ; Langmuir-Gleichung ; Chemistry ; Polymer and Materials Science
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology , Process Engineering, Biotechnology, Nutrition Technology
    Additional Material: 2 Ill.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/cite.330511220
    Location Call Number Expected Availability
    BibTip Others were also interested in ...
    Paper (German National Licenses)
    Fulltext
  • 69
    Electronic Resource
    Electronic Resource
    Die Abscheidung von Nebeltropfen in Lamellenbündeln (1979)
    Weinheim : Wiley-Blackwell
    Chemie Ingenieur Technik - CIT 51 (1979), S. 1255-1255 
    Details
    ISSN: 0009-286X
    Keywords: Tropfenabsceidung ; Lamellenabsceider ; Chemistry ; Polymer and Materials Science
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology , Process Engineering, Biotechnology, Nutrition Technology
    Additional Material: 3 Ill.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/cite.330511223
    Location Call Number Expected Availability
    BibTip Others were also interested in ...
    Paper (German National Licenses)
    Fulltext
  • 70
    Electronic Resource
    Electronic Resource
    Vapor-Liquid Equilibrium Data Collection, Vol. I, Part 2b “Organic Hydroxy Compounds: Alcohols and Phenols”. Von J. Gmehling, U. Onken und W. Arlt. Herausgeg. von der DECHEMA, D. Behrens, R. Eckermann. Bischoff-Verlag, Frankfurt/M. 1978. 1. Aufl., XVIII, 556 S., zahlr. Abb. u. Tab., geb., DM 142,- (1979)
    Weinheim : Wiley-Blackwell
    Chemie Ingenieur Technik - CIT 51 (1979), S. 1258-1258 
    Details
    ISSN: 0009-286X
    Keywords: Chemistry ; Polymer and Materials Science
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology , Process Engineering, Biotechnology, Nutrition Technology
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/cite.330511226
    Location Call Number Expected Availability
    BibTip Others were also interested in ...
    Paper (German National Licenses)
    Fulltext
  • 71
    Electronic Resource
    Electronic Resource
    Aktuelle Nachrichten (1979)
    Weinheim : Wiley-Blackwell
    Chemie Ingenieur Technik - CIT 51 (1979), S. A204 
    Details
    ISSN: 0009-286X
    Keywords: Chemistry ; Polymer and Materials Science
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology , Process Engineering, Biotechnology, Nutrition Technology
    Additional Material: 2 Ill.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/cite.330510402
    Location Call Number Expected Availability
    BibTip Others were also interested in ...
    Paper (German National Licenses)
    Fulltext
  • 72
    Electronic Resource
    Electronic Resource
    Fortschritte bei der Modellierung von FestbettreaktorenVortrag auf dem Jahrestreffen der Verfahrens-Ingenieure, 27. bis 29. September 1978 in Aachen. (1979)
    Weinheim : Wiley-Blackwell
    Chemie Ingenieur Technik - CIT 51 (1979), S. 257-265 
    Details
    ISSN: 0009-286X
    Keywords: Chemistry ; Polymer and Materials Science
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: Progress in the modeling of fixed bed reactors. Recent work on the modeling of catalytic fixed bed reactors have led to more realistic mathematical models and to a better understanding of problems connected with modeling. Nowadays standard routine computer programs are available for use in the design (and analysis) of catalytic fixed bed reactors for very complex reaction systems. The influence of bed structure on transport parameters was illustrated by experimental determination of axial and radial concentration and temperature distribution. Moreover the problem of multicomponent diffusion coupled with complex reactions in porous catalysts has been solved and can be included in the reactor model. However, the practical application of possible reactor models is limited by the availability of transport parameters for fixed beds.
    Additional Material: 11 Ill.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/cite.330510403
    Location Call Number Expected Availability
    BibTip Others were also interested in ...
    Paper (German National Licenses)
    Fulltext
  • 73
    Electronic Resource
    Electronic Resource
    Charakterisierung von AgglomeratenVortrag von R. Polke auf dem Jahrestreffen der Verfahrensingenieure, 27. bis 29. September 1978 in Aachen. (1979)
    Weinheim : Wiley-Blackwell
    Chemie Ingenieur Technik - CIT 51 (1979), S. 283-288 
    Details
    ISSN: 0009-286X
    Keywords: Chemistry ; Polymer and Materials Science
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: Characterization of agglomerates. Methods of determining the properties of agglomerates are surveyed. In particular, the article presents and compares various methods for establishing porosity, strength, and rates of dispersion and dissolution. The accuracy and scope of the specific methods are discussed.
    Additional Material: 9 Ill.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/cite.330510406
    Location Call Number Expected Availability
    BibTip Others were also interested in ...
    Paper (German National Licenses)
    Fulltext
  • 74
    Electronic Resource
    Electronic Resource
    Behinderte Sedimentation in ZentrifugenVortrag auf dem Jahrestreffen der Verfahrens-Ingenieure, 27. bis 29. Sept. 1978 in Aachen. (1979)
    Weinheim : Wiley-Blackwell
    Chemie Ingenieur Technik - CIT 51 (1979), S. 333-333 
    Details
    ISSN: 0009-286X
    Keywords: Zentrifugen ; Sedimentation ; Stokes-Gleichung ; Chemistry ; Polymer and Materials Science
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology , Process Engineering, Biotechnology, Nutrition Technology
    Additional Material: 3 Ill.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/cite.330510424
    Location Call Number Expected Availability
    BibTip Others were also interested in ...
    Paper (German National Licenses)
    Fulltext
  • 75
    Electronic Resource
    Electronic Resource
    Prozeß und AnlagentechnikBerichterstatter: Dr.-Ing. H. Hauser, BASF Aktiengesellschaft, 6700 Ludwigshafen Rh., und Prof. Dr.-Ing. H. Schwind, Lehrstuhl für Anlagentechnik der Universität Dortmund, Abt. Chemietechnik, Postfach 500 500, 4600 Dortmund 50. Bericht über die vorige Sitzung s. Chem.-Ing.-Tech. 49 (1977) S. 276. (1979)
    Weinheim : Wiley-Blackwell
    Chemie Ingenieur Technik - CIT 51 (1979), S. 341-344 
    Details
    ISSN: 0009-286X
    Keywords: Chemistry ; Polymer and Materials Science
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology , Process Engineering, Biotechnology, Nutrition Technology
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/cite.330510426
    Location Call Number Expected Availability
    BibTip Others were also interested in ...
    Paper (German National Licenses)
    Fulltext
  • 76
    Electronic Resource
    Electronic Resource
    Nachbehandlung von Halbzeugen und Apparaten aus austenitischen Stählen zur Vermeidung von SpannungsrißkorrosionVortrag auf dem Jahrestreffen der Verfahrens-Ingenieure, 27. bis 29. Sept. 1978 in Aachen. (1979)
    Weinheim : Wiley-Blackwell
    Chemie Ingenieur Technik - CIT 51 (1979), S. 402-406 
    Details
    ISSN: 0009-286X
    Keywords: Chemistry ; Polymer and Materials Science
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: After-treatment of semifinished products and equipment made of austenitic steel to avoid stress corrosion. Among the factors initiating stress corrosion, the extent and distribution of internal tensile stress are the least tractable. Unknown internal stresses are always superposed on the estimable operational stresses. If they arise from distortions or welding, the former are distributed throughout the entire cross-section. The action of tools, e.g. on turning or grinding, can also lead to high internal tensile stresses in a thin surface zone. Such stresses are of particular significance because stress corrosion is initiated on the surface. In this article, it is shown that it is usually sufficient to adequately reduce these surface-proximate internal tensile stresses, e.g. by a pickling process removing a surface layer of material, in order to eliminate stress corrosion and thus to extend the scope of austenitic steels. Should the internal tensile stresses due to distortion and welding suffice to initiate stress corrosion under particularly aggressive conditions, one can attempt to reduce the stress by suitable heat treatment; however, no impermissable change in the microstructure of the steel may occur. Finally, it is also possible to produce compressive stress in a thin surface zone by shot peening so that no stress corrosion can take place. The advantages and disadvantages of the various possibilities are illustrated with the aid of examples.
    Additional Material: 8 Ill.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/cite.330510509
    Location Call Number Expected Availability
    BibTip Others were also interested in ...
    Paper (German National Licenses)
    Fulltext
  • 77
    Electronic Resource
    Electronic Resource
    Zum Stand der Berechnung von Behälterabstützungen und FußkonstruktionenVortrag auf der Tagung „Auslegung, Herstellung und Prüfung von Druckbehältern“ am 13. 11. 1978 in Essen und in ähnlicher Fassung auf der DECHEMA-Jahrestagung am 16. Juni 1978 in Frankfurt/M. (1979)
    Weinheim : Wiley-Blackwell
    Chemie Ingenieur Technik - CIT 51 (1979), S. 447-451 
    Details
    ISSN: 0009-286X
    Keywords: Chemistry ; Polymer and Materials Science
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: Calculation of vessel supports and foot constructions. Supports of vessels often cause large strains in the wall of the container; generally the calculation of the resulting deformations and stresses turns out to be difficult. Several types of construction and the problems associated with local loadings are described, and possible methods of calculation are listed. Generally known publications are compared. Methods of series expansion are considered in more detail and their advantages as well as their limitations are shown for the example of a Fourier series expansion for a cylindrical tank. In addition two examples are considered which permit comparisons between our own calculations and usual methods and experimental results, respectively.
    Additional Material: 6 Ill.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/cite.330510513
    Location Call Number Expected Availability
    BibTip Others were also interested in ...
    Paper (German National Licenses)
    Fulltext
  • 78
    Electronic Resource
    Electronic Resource
    Kritische Anmerkungen zur Untersuchung an Zyklonabscheidern (1979)
    Weinheim : Wiley-Blackwell
    Chemie Ingenieur Technik - CIT 51 (1979), S. 493-496 
    Details
    ISSN: 0009-286X
    Keywords: Chemistry ; Polymer and Materials Science
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology , Process Engineering, Biotechnology, Nutrition Technology
    Additional Material: 12 Ill.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/cite.330510518
    Location Call Number Expected Availability
    BibTip Others were also interested in ...
    Paper (German National Licenses)
    Fulltext
  • 79
    Electronic Resource
    Electronic Resource
    Strömungsgeschwindigkeitsprofile für verschiedene Rührorgane in einem bewehrten RührapparatMitteilung aus dem Sonderforschungsbereich 153 „Reaktions-und Austauschtechnik disperser Zweiphasensysteme“, Teilprojekt D 1 „Das Strömungsfeld im Rührapparat“. (1979)
    Weinheim : Wiley-Blackwell
    Chemie Ingenieur Technik - CIT 51 (1979), S. 498-500 
    Details
    ISSN: 0009-286X
    Keywords: Chemistry ; Polymer and Materials Science
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology , Process Engineering, Biotechnology, Nutrition Technology
    Additional Material: 5 Ill.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/cite.330510520
    Location Call Number Expected Availability
    BibTip Others were also interested in ...
    Paper (German National Licenses)
    Fulltext
  • 80
    Electronic Resource
    Electronic Resource
    Pharmazeutische Technologie. Herausgeg. von H. Sucker, P. Fuchs, und P. Speiser. Georg-Thieme-Verlag, Stuttgart 1978. 1. Aufl., XX, 906 S., 319 Abb., 180 Tab., geb., DM 235,- (1979)
    Weinheim : Wiley-Blackwell
    Chemie Ingenieur Technik - CIT 51 (1979), S. 508-508 
    Details
    ISSN: 0009-286X
    Keywords: Chemistry ; Polymer and Materials Science
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology , Process Engineering, Biotechnology, Nutrition Technology
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/cite.330510523
    Location Call Number Expected Availability
    BibTip Others were also interested in ...
    Paper (German National Licenses)
    Fulltext
  • 81
    Electronic Resource
    Electronic Resource
    Kinetik der eisenkatalysierten Wasserdampf-Druckvergasung von Koks (1979)
    Weinheim : Wiley-Blackwell
    Chemie Ingenieur Technik - CIT 51 (1979), S. 519-519 
    Details
    ISSN: 0009-286X
    Keywords: Vergasung ; Petrolkoks ; Wasserdampf ; Katalyse ; Eisen ; Kinetik ; Festbett ; Druck ; Chemistry ; Polymer and Materials Science
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology , Process Engineering, Biotechnology, Nutrition Technology
    Additional Material: 1 Ill.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/cite.330510526
    Location Call Number Expected Availability
    BibTip Others were also interested in ...
    Paper (German National Licenses)
    Fulltext
  • 82
    Electronic Resource
    Electronic Resource
    Umweltbewußte Inbetriebnahme von Olefin-AnlagenVortrag auf dem Linde-Olefinsymposium vom 10. bis 12. 10. 1978 in München. (1979)
    Weinheim : Wiley-Blackwell
    Chemie Ingenieur Technik - CIT 51 (1979), S. 526-527 
    Details
    ISSN: 0009-286X
    Keywords: Anfahren von Olefin-Anlagen ; Umweltschutz ; Montage ; Äthylen ; Chemistry ; Polymer and Materials Science
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology , Process Engineering, Biotechnology, Nutrition Technology
    Additional Material: 3 Ill.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/cite.330510530
    Location Call Number Expected Availability
    BibTip Others were also interested in ...
    Paper (German National Licenses)
    Fulltext
  • 83
    Electronic Resource
    Electronic Resource
    Temperaturabhängigkeit des AktivitätskoeffizientenVortrag auf der internen ArbeitssitzungdesGVC-Fachausschuses „Thermische Zerlegung von Flüssigkeits-und Gasgemischen“ am 24. April 1978 in Bamberg. (1979)
    Weinheim : Wiley-Blackwell
    Chemie Ingenieur Technik - CIT 51 (1979), S. 496-497 
    Details
    ISSN: 0009-286X
    Keywords: Chemistry ; Polymer and Materials Science
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology , Process Engineering, Biotechnology, Nutrition Technology
    Additional Material: 2 Ill.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/cite.330510519
    Location Call Number Expected Availability
    BibTip Others were also interested in ...
    Paper (German National Licenses)
    Fulltext
  • 84
    Electronic Resource
    Electronic Resource
    Auslegung von Kolonnen für die Nitrosegas-Absorption bei der Salpetersäure-Herstellung (1979)
    Weinheim : Wiley-Blackwell
    Chemie Ingenieur Technik - CIT 51 (1979), S. 516-517 
    Details
    ISSN: 0009-286X
    Keywords: Nitrosegas-Absorption ; Stofftransport mit Reaktion ; Computer-Programm zur Kolonnenberechnung ; Relaxationsmethode ; Chemistry ; Polymer and Materials Science
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology , Process Engineering, Biotechnology, Nutrition Technology
    Additional Material: 1 Ill.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/cite.330510525
    Location Call Number Expected Availability
    BibTip Others were also interested in ...
    Paper (German National Licenses)
    Fulltext
  • 85
    Electronic Resource
    Electronic Resource
    Zertropfen von Flüssigkeiten mittels Druckschwingungen (1979)
    Weinheim : Wiley-Blackwell
    Chemie Ingenieur Technik - CIT 51 (1979), S. 525-525 
    Details
    ISSN: 0009-286X
    Keywords: Tropfenbildung ; Zertropfen ; Zerstäuben von Flüssigkeiten ; Zerstäuber ; Vibratiosns-Zerstäubung ; Chemistry ; Polymer and Materials Science
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology , Process Engineering, Biotechnology, Nutrition Technology
    Additional Material: 2 Ill.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/cite.330510529
    Location Call Number Expected Availability
    BibTip Others were also interested in ...
    Paper (German National Licenses)
    Fulltext
  • 86
    Electronic Resource
    Electronic Resource
    Gas/Feststoff-Rieselströmung in einer FüllkörperkolonneVortrag von A. W. M. Roes auf dem Jahrestreffen der Verfahrens-Ingenieure, 27. bis 29. September 1978 in Aachen. (1979)
    Weinheim : Wiley-Blackwell
    Chemie Ingenieur Technik - CIT 51 (1979), S. 529-529 
    Details
    ISSN: 0009-286X
    Keywords: Füllkörperkolonne ; Mehrphasenströmung ; Gas/Feststoff-Strömung ; Axialvermischung ; Stoffübergang ; Chemistry ; Polymer and Materials Science
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology , Process Engineering, Biotechnology, Nutrition Technology
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/cite.330510531
    Location Call Number Expected Availability
    BibTip Others were also interested in ...
    Paper (German National Licenses)
    Fulltext
  • 87
    Electronic Resource
    Electronic Resource
    Elektrische Energie und UmweltVortrag von K. H. Krieb auf der Tagung der GDCh-Fachgruppe „Angewandte Elektrochemie“, 4. bis 6. Okt. 1978 in Berlin. (1979)
    Weinheim : Wiley-Blackwell
    Chemie Ingenieur Technik - CIT 51 (1979), S. 575-578 
    Details
    ISSN: 0009-286X
    Keywords: Chemistry ; Polymer and Materials Science
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: Electrical energy and environmental protection. Power plant affect their environments by emitting noise, heat, and air pollutants, but can be operated, according to the present state of the art, in such a way as to lessen these effects. The noise levels will then be below those of a quiet restaurant; the heat emission above the cooling tower will influence neither climate nor the volume of rainfall, and will influence the amount of incident solar radiation to only a minor degree; the dust emission in g/k Wh has decreased by 97% during the last 30 years; the SO2 emission will have decreased by 80% by 1980; the dilution of the SO2 emission through use of high stacks will lead to maximum SO2 levels of 2 μg/m3 in case of modern power plants; all these are low values compared with the upper limits of 140 μg/m3 permitted by the “Technische Anleitung Luft”. It is worth mentioning in connection with the problems with present environmental protection that the per capita electricity consumption of private households has increased much faster than that of industry.
    Additional Material: 4 Ill.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/cite.330510606
    Location Call Number Expected Availability
    BibTip Others were also interested in ...
    Paper (German National Licenses)
    Fulltext
  • 88
    Electronic Resource
    Electronic Resource
    Technische und wirtschaftliche Überlegungen zur Elektrotraktion - VW-Elektro-TransporterVortrag auf der Tagung der GDCh-Fachgruppe „Angewandte Elektrochemie“, 4. bis 6. Okt. 1978 in Berlin. (1979)
    Weinheim : Wiley-Blackwell
    Chemie Ingenieur Technik - CIT 51 (1979), S. 593-596 
    Details
    ISSN: 0009-286X
    Keywords: Chemistry ; Polymer and Materials Science
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: Technical and economic aspects of electrically powered VW commercial vehicles. The article first describes the “VW Electric Delivery Truck System”, consisting of the vehicle and the peripheral equipment to operate it, and then reports experience gained with this type of vehicle, of which more than 70 have been registered for operation on public roads since 1972. On the basis of these VW commercial vehicles, which are equipped with lead-acid batteries, the authors discuss the potential advantages of using new types of batteries with twice the energy to weight ratio. The resulting vehicle versions and their total weights, payloads, battery weights, energy requirements, and operating costs are reviewed. It is shown that a considerably higher price for batteries with twice the energy/weight ratio would be acceptable under certain circumstances.
    Additional Material: 4 Ill.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/cite.330510608
    Location Call Number Expected Availability
    BibTip Others were also interested in ...
    Paper (German National Licenses)
    Fulltext
  • 89
    Electronic Resource
    Electronic Resource
    Feuerfest-Siliciumcarbid. Von E. H. P. Wecht. Spring-Verlag, Wien - New York 1977. XII, 276 S., 142 Abb., geb., DM 116, - (1979)
    Weinheim : Wiley-Blackwell
    Chemie Ingenieur Technik - CIT 51 (1979), S. 548-548 
    Details
    ISSN: 0009-286X
    Keywords: Chemistry ; Polymer and Materials Science
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology , Process Engineering, Biotechnology, Nutrition Technology
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/cite.330510545
    Location Call Number Expected Availability
    BibTip Others were also interested in ...
    Paper (German National Licenses)
    Fulltext
  • 90
    Electronic Resource
    Electronic Resource
    Entsorgungssystem galvanischer Betriebe auf der Basis von Selektivionenaustauschern und zentralen AufarbeitungsstationenVortrag von R. Meixlsperger auf der Tagung der GDCh-Fachgruppe „Angewandte Elektrochemie“, 4. bis 6. Okt. 1978 in Berlin. (1979)
    Weinheim : Wiley-Blackwell
    Chemie Ingenieur Technik - CIT 51 (1979), S. 639-640 
    Details
    ISSN: 0009-286X
    Keywords: Chemistry ; Polymer and Materials Science
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology , Process Engineering, Biotechnology, Nutrition Technology
    Additional Material: 1 Ill.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/cite.330510614
    Location Call Number Expected Availability
    BibTip Others were also interested in ...
    Paper (German National Licenses)
    Fulltext
  • 91
    Electronic Resource
    Electronic Resource
    Eine Wirbelbettelektrolysezelle zur Entfernung von Metallen aus AbwasserVortrag auf der Tagung der GDCh-Fachgruppe „Angewandte Elektrochemie“, 4. bis 6. Okt. 1978 in Berlin. (1979)
    Weinheim : Wiley-Blackwell
    Chemie Ingenieur Technik - CIT 51 (1979), S. 651-653 
    Details
    ISSN: 0009-286X
    Keywords: Chemistry ; Polymer and Materials Science
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology , Process Engineering, Biotechnology, Nutrition Technology
    Additional Material: 5 Ill.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/cite.330510618
    Location Call Number Expected Availability
    BibTip Others were also interested in ...
    Paper (German National Licenses)
    Fulltext
  • 92
    Electronic Resource
    Electronic Resource
    Umweltbelastung und Sicherheitsfaktoren elektrochemischer Speichersysteme zur SpitzenlastdeckungVortrag auf der Tagung der GDCh-Fachgruppe „Angewandte Elektrochemie“, 4. bis 6. Okt. 1978 in Berlin. (1979)
    Weinheim : Wiley-Blackwell
    Chemie Ingenieur Technik - CIT 51 (1979), S. 659-662 
    Details
    ISSN: 0009-286X
    Keywords: Chemistry ; Polymer and Materials Science
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology , Process Engineering, Biotechnology, Nutrition Technology
    Additional Material: 2 Ill.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/cite.330510621
    Location Call Number Expected Availability
    BibTip Others were also interested in ...
    Paper (German National Licenses)
    Fulltext
  • 93
    Electronic Resource
    Electronic Resource
    Verwendung elektrochemisch wirksamer Katalysatoren bei der Abwasser-BehandlungVortrag auf der Tagung der GDCh-Fachgruppe „Angewandte Elektrochemie“, 4. bis 6. Oktober 1978 in Berlin. (1979)
    Weinheim : Wiley-Blackwell
    Chemie Ingenieur Technik - CIT 51 (1979), S. 666-667 
    Details
    ISSN: 0009-286X
    Keywords: Chemistry ; Polymer and Materials Science
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology , Process Engineering, Biotechnology, Nutrition Technology
    Additional Material: 3 Ill.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/cite.330510624
    Location Call Number Expected Availability
    BibTip Others were also interested in ...
    Paper (German National Licenses)
    Fulltext
  • 94
    Electronic Resource
    Electronic Resource
    Ein verallgemeinertes Verfahren zur rechnerischen Auslegung und Überprüfung von Sprühtürmen (1979)
    Weinheim : Wiley-Blackwell
    Chemie Ingenieur Technik - CIT 51 (1979), S. 674-675 
    Details
    ISSN: 0009-286X
    Keywords: Erstarrung ; Sprühturm ; Wärmeleitung ; Wärmeaustauscher ; Rechenmodell ; Chemistry ; Polymer and Materials Science
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology , Process Engineering, Biotechnology, Nutrition Technology
    Additional Material: 1 Ill.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/cite.330510628
    Location Call Number Expected Availability
    BibTip Others were also interested in ...
    Paper (German National Licenses)
    Fulltext
  • 95
    Electronic Resource
    Electronic Resource
    Entwicklungsarbeiten an Nickel/Wasserstoff-Zellen für die ElektrotraktionVortrag auf der Tagung der GDCh-Fachgruppe „Angewandte Elektrochemie“, 4. bis 6. Oktober 1978 in Berlin. (1979)
    Weinheim : Wiley-Blackwell
    Chemie Ingenieur Technik - CIT 51 (1979), S. 657-659 
    Details
    ISSN: 0009-286X
    Keywords: Chemistry ; Polymer and Materials Science
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology , Process Engineering, Biotechnology, Nutrition Technology
    Additional Material: 3 Ill.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/cite.330510620
    Location Call Number Expected Availability
    BibTip Others were also interested in ...
    Paper (German National Licenses)
    Fulltext
  • 96
    Electronic Resource
    Electronic Resource
    Fluor-Emission - Ein Problem der Aluminium-Elektrolyse und seine LösungKurzfassung des Vortrags auf der Tagung der GDCh-Fachgruppe „Angewandte Elektrochemie“, 4. bis 6. Okt. 1978 in Berlin. (1979)
    Weinheim : Wiley-Blackwell
    Chemie Ingenieur Technik - CIT 51 (1979), S. 664-665 
    Details
    ISSN: 0009-286X
    Keywords: Chemistry ; Polymer and Materials Science
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology , Process Engineering, Biotechnology, Nutrition Technology
    Additional Material: 1 Ill.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/cite.330510623
    Location Call Number Expected Availability
    BibTip Others were also interested in ...
    Paper (German National Licenses)
    Fulltext
  • 97
    Electronic Resource
    Electronic Resource
    Emailkorrosionsprüfung mit Autoklaven (1979)
    Weinheim : Wiley-Blackwell
    Chemie Ingenieur Technik - CIT 51 (1979), S. 671-671 
    Details
    ISSN: 0009-286X
    Keywords: Emailprüfung ; Autoklav ; Korrosion ; Normung ; Chemistry ; Polymer and Materials Science
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology , Process Engineering, Biotechnology, Nutrition Technology
    Additional Material: 2 Ill.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/cite.330510626
    Location Call Number Expected Availability
    BibTip Others were also interested in ...
    Paper (German National Licenses)
    Fulltext
  • 98
    Electronic Resource
    Electronic Resource
    Der Einfluß von Niederschlag auf den Betrieb eines Naturzug-TrockenkühlturmsErweiterte Fassung eines Vortrags von P. Herberholz auf der Sitzung des GVC-Fachausschusses „Wärme- und Stoffübertragung“ am 20./21. April 1978 in Würzburg. (1979)
    Weinheim : Wiley-Blackwell
    Chemie Ingenieur Technik - CIT 51 (1979), S. 677-677 
    Details
    ISSN: 0009-286X
    Keywords: Kraftwerkskühlung ; Kühltürme ; Trockenkühltürme ; Wärmeaustauscher ; Wärme- und Stoffaustausch (Tropfen/Luft) ; Chemistry ; Polymer and Materials Science
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology , Process Engineering, Biotechnology, Nutrition Technology
    Additional Material: 2 Ill.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/cite.330510629
    Location Call Number Expected Availability
    BibTip Others were also interested in ...
    Paper (German National Licenses)
    Fulltext
  • 99
    Electronic Resource
    Electronic Resource
    Experimentelle Hochdruckmethodik. IV. Entwicklung eines Differential-Kreislaufreaktors für Untersuchungen heterogener Systeme mit fluiden Phasen bei hohen Drücken und Temperaturen (1979)
    Weinheim : Wiley-Blackwell
    Chemie Ingenieur Technik - CIT 51 (1979), S. 682-683 
    Details
    ISSN: 0009-286X
    Keywords: Differential-Kreislaufreaktor ; Hochdruck ; Reaktionstechnik ; Austauschtechnik ; Reaktionskinetik ; Makrokinetik ; Kontaktkatalyse ; Stoffübergang ; Extraktion ; Chemistry ; Polymer and Materials Science
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology , Process Engineering, Biotechnology, Nutrition Technology
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/cite.330510632
    Location Call Number Expected Availability
    BibTip Others were also interested in ...
    Paper (German National Licenses)
    Fulltext
  • 100
    Electronic Resource
    Electronic Resource
    Internationales Symposium „Liquid-Solid Filtration“Berichterstatter: Prof. Dr.-Ing. Chr. Alt, Lehrstuhl und Institut für Mechanische Verfahrenstechnik der Universität Stuttgart, Böblinger Str. 72, 7000 Stuttgart 1. (1979)
    Weinheim : Wiley-Blackwell
    Chemie Ingenieur Technik - CIT 51 (1979), S. 688-691 
    Details
    ISSN: 0009-286X
    Keywords: Chemistry ; Polymer and Materials Science
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology , Process Engineering, Biotechnology, Nutrition Technology
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/cite.330510635
    Location Call Number Expected Availability
    BibTip Others were also interested in ...
    Paper (German National Licenses)
    Fulltext
Close ⊗
This website uses cookies and the analysis tool Matomo. More information can be found here...