Genetic linkage of C3H/HeJ and BALB/c endogenous ecotropic C-type viruses to phosphoglucomutase-1 on chromosome 5

Science. 1979 Apr 6;204(4388):71-3. doi: 10.1126/science.219476.

Abstract

The genetic linkage of the endogenous C3H/HeJ C-type ecotropic virus to phosphoglucomutase-1 (0.28, recombinant fraction) on chromosome 5 was established by means of serological assays of backcrossed mice. With a combination of serological techniques and DNA-DNA hybridization the BALB/c endogenous ecotropic virus was shown to be either closely linked or allelic with the C3H/HeJ locus.

Publication types

  • Research Support, U.S. Gov't, P.H.S.

MeSH terms

  • Alleles
  • Animals
  • Genes
  • Genes, Viral*
  • Genetic Linkage
  • Leukemia Virus, Murine / genetics
  • Mice
  • Mice, Inbred BALB C / microbiology*
  • Mice, Inbred C3H / microbiology*
  • Mice, Inbred Strains / genetics
  • Phenotype
  • Phosphoglucomutase / genetics*
  • Retroviridae / genetics*

Substances

  • Phosphoglucomutase