ALBERT

All Library Books, journals and Electronic Records Telegrafenberg

X
feed icon rss

Your email was sent successfully. Check your inbox.

An error occurred while sending the email. Please try again.

Proceed reservation?

Export
Filter
  • Chemistry  (81,411)
  • SPACE VEHICLES
  • 1980-1984  (33,715)
  • 1970-1974  (29,858)
  • 1960-1964  (20,834)
Collection
Keywords
Publisher
Years
Year
  • 1
    facet.materialart.
    Unknown
    Rational approaches to chemotherapy: antisickling agents (1981)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1981-08-14
    Description: 〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Klotz, I M -- Haney, D N -- King, L C -- New York, N.Y. -- Science. 1981 Aug 14;213(4509):724-31.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/7256275" target="_blank"〉PubMed〈/a〉
    Keywords: Anemia, Sickle Cell/*drug therapy ; Aspirin/analogs & derivatives/therapeutic use ; Chemical Phenomena ; Chemistry ; *Hemoglobin, Sickle ; Humans ; Protein Binding/drug effects ; Protein Conformation ; Salicylates/*therapeutic use ; Solubility ; Structure-Activity Relationship
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
    Published by American Association for the Advancement of Science (AAAS)
    Location Call Number Expected Availability
    BibTip Others were also interested in ...
    PAPER CURRENT
  • 2
    facet.materialart.
    Unknown
    Alpha-substituted gamma-butyrolactones: new class of anticonvulsant drugs (1982)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1982-09-10
    Description: Alkyl-Substituted gamma-butyrolactones were synthesized and tested for their convulsant and anticonvulsant actions in mice and guinea pigs. The alpha-substituted compounds, alpha, alpha-dimethyl-, and alpha-ethyl-alpha-methyl-gamma-butyrolactone were anticonvulsant compounds with a spectrum of activity similar to that of ethosuximide. In contrast, beta-substituted compounds were convulsant agents similar to picrotoxinin. The alpha-substituted-gama-butyrolactones represent a new class of anticonvulsant drug with experimental and clinical potential.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Klunk, W E -- McKeon, A -- Covey, D F -- Ferrendelli, J A -- GM-07200/GM/NIGMS NIH HHS/ -- GM-24483/GM/NIGMS NIH HHS/ -- NS-14834/NS/NINDS NIH HHS/ -- etc. -- New York, N.Y. -- Science. 1982 Sep 10;217(4564):1040-2.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/6810462" target="_blank"〉PubMed〈/a〉
    Keywords: *4-Butyrolactone/analogs & derivatives/*therapeutic use/toxicity ; Animals ; *Anticonvulsants ; Chemical Phenomena ; Chemistry ; Convulsants ; Drug Evaluation, Preclinical ; Electroencephalography ; Epilepsy, Absence/drug therapy ; Ethosuximide/pharmacology ; *Furans/*therapeutic use ; Guinea Pigs ; Mice ; Structure-Activity Relationship ; Trimethadione/pharmacology
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
    Published by American Association for the Advancement of Science (AAAS)
    Location Call Number Expected Availability
    BibTip Others were also interested in ...
    PAPER CURRENT
  • 3
    facet.materialart.
    Unknown
    Phase transition and crystal structure of the 37 degrees C form of cholesterol (1983)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1983-05-06
    Description: Crystalline cholesterol undergoes a phase transition a few degrees below human body temperature. The high-temperature form has an unusually complex structure with 16 independent molecules. In the transition two molecules change side chain conformation, four reorient about their long axes, and ten remain unchanged. The transition mechanism implies relatively nonspecific intermolecular interactions, qualitatively consistent with the behavior of cholesterol in biomembranes. The transition preserves a remarkably closely obeyed pseudosymmetry present in the structure.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Hsu, L Y -- Nordman, C E -- GM15259/GM/NIGMS NIH HHS/ -- New York, N.Y. -- Science. 1983 May 6;220(4597):604-6.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/6836303" target="_blank"〉PubMed〈/a〉
    Keywords: Body Temperature ; Chemical Phenomena ; Chemistry ; *Cholesterol ; Crystallization ; Humans ; Magnetic Resonance Spectroscopy ; Molecular Conformation
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
    Published by American Association for the Advancement of Science (AAAS)
    Location Call Number Expected Availability
    BibTip Others were also interested in ...
    PAPER CURRENT
  • 4
    facet.materialart.
    Unknown
    Cytochrome a3 structure in carbon monoxide-bound cytochrome oxidase (1984)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1984-07-20
    Description: The iron-carbon monoxide stretching mode and the iron-carbon-oxygen bending mode in carbon monoxide-bound cytochrome oxidase have been assigned at 520 and 578 cm-1, respectively. The frequencies, widths, and intensities of these modes show that the Fe-C-O grouping in carbon monoxide-cytochrome a3 is linear but tilted from the normal to the heme plane; that the iron-histidine bond in both five- and six-coordinate cytochrome a3 is strained; and that the carbon monoxide and the proximal histidine each have characteristic, well-defined orientations in all molecules. These data can account for the binding affinities of carbon monoxide and dioxygen under physiological conditions.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Argade, P V -- Ching, Y C -- Rousseau, D L -- New York, N.Y. -- Science. 1984 Jul 20;225(4659):329-31.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/6330890" target="_blank"〉PubMed〈/a〉
    Keywords: Animals ; Carbon Monoxide/metabolism ; Cattle ; Chemical Phenomena ; Chemistry ; Electron Transport Complex IV/*metabolism ; Myoglobin/metabolism ; Oxidation-Reduction ; Oxygen/metabolism ; Spectrum Analysis, Raman
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
    Published by American Association for the Advancement of Science (AAAS)
    Location Call Number Expected Availability
    BibTip Others were also interested in ...
    PAPER CURRENT
  • 5
    facet.materialart.
    Unknown
    Leukotrienes: mediators of immediate hypersensitivity reactions and inflammation (1983)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1983-05-06
    Description: Arachidonic acid plays a central role in a biological control system where such oxygenated derivatives as prostaglandins, thromboxanes, and leukotrienes are mediators. The leukotrienes are formed by transformation of arachidonic acid into an unstable epoxide intermediate, leukotriene A4, which can be converted enzymatically by hydration to leukotriene B4, and by addition of glutathione to leukotriene C4. This last compound is metabolized to leukotrienes D4 and E4 by successive elimination of a gamma-glutamyl residue and glycine. Slow-reacting substance of anaphylaxis consists of leukotrienes C4, D4, and E4. The cysteinyl-containing leukotrienes are potent bronchoconstrictors, increase vascular permeability in postcapillary venules, and stimulate mucus secretion. Leukotriene B4 causes adhesion and chemotactic movement of leukocytes and stimulates aggregation, enzyme release, and generation of superoxide in neutrophils. Leukotrienes C4, D4, and E4, which are released from the lung tissue of asthmatic subjects exposed to specific allergens, seem to play a pathophysiological role in immediate hypersensitivity reactions. These leukotrienes, as well as leukotriene B4, have pro-inflammatory effects.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Samuelsson, B -- New York, N.Y. -- Science. 1983 May 6;220(4597):568-75.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/6301011" target="_blank"〉PubMed〈/a〉
    Keywords: Animals ; Arachidonic Acids/metabolism/pharmacology/physiology ; Bronchi/drug effects ; Cats ; Chemical Phenomena ; Chemistry ; Cricetinae ; Guinea Pigs ; Haplorhini ; Humans ; Hypersensitivity, Immediate/*physiopathology ; Inflammation/*physiopathology ; Leukocytes/drug effects/metabolism ; Leukotriene B4/pharmacology/*physiology ; Mice ; Microcirculation/drug effects ; Rabbits ; Rats ; SRS-A/*physiology
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
    Published by American Association for the Advancement of Science (AAAS)
    Location Call Number Expected Availability
    BibTip Others were also interested in ...
    PAPER CURRENT
  • 6
    facet.materialart.
    Unknown
    Amphiphilic secondary structure: design of peptide hormones (1984)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1984-01-20
    Description: Peptide synthesis can be used for elucidating the roles of secondary structures in the specificity of hormones, antigens, and toxins. Intermediate sized peptides with these activities assume amphiphilic secondary structures in the presence of membranes. When models are designed to optimize the amphiphilicity of the secondary structure, stronger interactions can be observed with the synthetic peptides than with the naturally occurring analogs.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Kaiser, E T -- Kezdy, F J -- HL-18577/HL/NHLBI NIH HHS/ -- New York, N.Y. -- Science. 1984 Jan 20;223(4633):249-55.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/6322295" target="_blank"〉PubMed〈/a〉
    Keywords: Amino Acid Sequence ; Apolipoprotein A-I ; Apolipoproteins ; Binding Sites ; Calcitonin ; Chemical Phenomena ; Chemistry ; Corticotropin-Releasing Hormone ; Endorphins ; Glucagon ; Growth Hormone-Releasing Hormone ; *Hormones/pharmacology ; Lipoproteins, HDL ; Melitten ; Models, Structural ; *Peptides/chemical synthesis/metabolism/pharmacology ; Protein Conformation ; Structure-Activity Relationship ; beta-Endorphin
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
    Published by American Association for the Advancement of Science (AAAS)
    Location Call Number Expected Availability
    BibTip Others were also interested in ...
    PAPER CURRENT
  • 7
    facet.materialart.
    Unknown
    Fourier transform mass spectrometry (1984)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1984-10-19
    Description: Fourier transform mass spectrometry will play an important role in the future because of its unique combination of high mass resolution, high upper mass limit, and multichannel advantage. These features have already found application in gas chromatography-mass spectrometry, multiphoton ionization, laser desorption, and secondary ion mass spectrometry. However, its most notable feature is the ability to store ions. This characteristic, when combined with the others, will allow expeditious study of the interaction of gas-phase ions with both photons (photodissociation) and neutral molecules, and the convenient application of this fundamental information for chemical analysis.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Gross, M L -- Rempel, D L -- 2-8423576/PHS HHS/ -- New York, N.Y. -- Science. 1984 Oct 19;226(4672):261-8.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/6385250" target="_blank"〉PubMed〈/a〉
    Keywords: Chemical Phenomena ; Chemistry ; *Fourier Analysis ; Ions ; Lasers ; *Mass Spectrometry/instrumentation/methods
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
    Published by American Association for the Advancement of Science (AAAS)
    Location Call Number Expected Availability
    BibTip Others were also interested in ...
    PAPER CURRENT
  • 8
    facet.materialart.
    Unknown
    Studying enzyme mechanism by 13C nuclear magnetic resonance (1984)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1984-08-31
    Description: High-resolution carbon-13 nuclear magnetic resonance (NMR) spectra of enzyme-inhibitor and enzyme-substrate complexes provide detailed structural and stereochemical information on the mechanism of enzyme action. The proteases trypsin and papain are shown to form tetrahedrally coordinated complexes and acyl derivatives with a variety of compounds artificially enriched at the site or sites of interest. These results are compared with the structural information derived from x-ray diffraction. Detailed NMR studies have provided a clearer picture of the ionization state of the residues participating in enzyme-catalyzed processes than other more classical techniques. The dynamics of enzymic catalysis can be observed at sub-zero temperatures by a combination of cryoenzymology and carbon-13 NMR spectroscopy. With these powerful techniques, transient, covalently bound intermediates in enzyme-catalyzed reactions can be detected and their structures rigorously assigned.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Mackenzie, N E -- Malthouse, J P -- Scott, A I -- New York, N.Y. -- Science. 1984 Aug 31;225(4665):883-9.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/6433481" target="_blank"〉PubMed〈/a〉
    Keywords: Binding Sites ; Carbon Isotopes ; Carboxypeptidases/metabolism ; Carboxypeptidases A ; Catalysis ; Chemical Phenomena ; Chemistry ; Coenzymes/*metabolism ; Endopeptidases/metabolism ; Enzymes/*metabolism ; Freezing ; Fructose-Bisphosphate Aldolase/metabolism ; Magnetic Resonance Spectroscopy ; Papain/metabolism ; Pepsin A/metabolism ; Peptide Hydrolases/*metabolism ; Protease Inhibitors ; Pterins/metabolism ; Pyridoxal Phosphate/metabolism ; Serine Endopeptidases
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
    Published by American Association for the Advancement of Science (AAAS)
    Location Call Number Expected Availability
    BibTip Others were also interested in ...
    PAPER CURRENT
  • 9
    facet.materialart.
    Unknown
    What is the risk from chlorofluorocarbons? (1984)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1984-03-09
    Description: 〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Maugh, T H 2nd -- New York, N.Y. -- Science. 1984 Mar 9;223(4640):1051-2.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/6695193" target="_blank"〉PubMed〈/a〉
    Keywords: *Air Pollutants ; *Atmosphere ; Carbon Tetrachloride ; Chemical Phenomena ; Chemistry ; *Chlorofluorocarbons, Methane ; Free Radicals ; Nitrogen Dioxide ; Nitrous Oxide ; Oxygen ; *Ozone ; Photochemistry ; Risk ; Singlet Oxygen ; Trichloroethanes ; Ultraviolet Rays
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
    Published by American Association for the Advancement of Science (AAAS)
    Location Call Number Expected Availability
    BibTip Others were also interested in ...
    PAPER CURRENT
  • 10
    facet.materialart.
    Unknown
    Pyrolysis mass spectrometry of complex organic materials (1984)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1984-10-19
    Description: Pyrolysis mass spectrometry in combination with computerized multivariate statistical analysis enables qualitative and quantitative analysis of nonvolatile organic materials containing molecular assemblies of a complexity and size far beyond the capabilities of direct mass spectrometry. The state of the art in pyrolysis mass spectrometry techniques is illustrated through specific applications, including structural determination and quality control of synthetic polymers, quantitative analysis of polymer mixtures, classification and structural characterization of fossil organic matter, and nonsupervised numerical extraction of component patterns from complex biological samples.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Meuzelaar, H L -- Windig, W -- Harper, A M -- Huff, S M -- McClennen, W H -- Richards, J M -- New York, N.Y. -- Science. 1984 Oct 19;226(4672):268-74.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/6484572" target="_blank"〉PubMed〈/a〉
    Keywords: Biochemical Phenomena ; Biochemistry ; Chemical Phenomena ; Chemistry ; Coal ; Enterobacteriaceae/analysis/isolation & purification ; Hot Temperature ; Mass Spectrometry/*methods ; Polymers
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
    Published by American Association for the Advancement of Science (AAAS)
    Location Call Number Expected Availability
    BibTip Others were also interested in ...
    PAPER CURRENT
  • 11
    facet.materialart.
    Unknown
    Lariat RNA's as intermediates and products in the splicing of messenger RNA precursors (1984)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1984-08-31
    Description: The splicing of messenger RNA precursors in vitro proceeds through an intermediate that has the 5' end of the intervening sequence joined to a site near the 3' splice site. This lariat structure, which has been characterized for an adenovirus 2 major late transcript, has a branch point, with 2'-5' and 3'-5' phosphodiester bonds emanating from a single adenosine residue. The excised intervening sequence retains the branch site and terminates in a guanosine residue with a 3' hydroxyl group. The phosphate group at the splice junction between the two exons originates from the 3' splice site at the precursor.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Padgett, R A -- Konarska, M M -- Grabowski, P J -- Hardy, S F -- Sharp, P A -- P01-CA14051/CA/NCI NIH HHS/ -- P01-CA26717/CA/NCI NIH HHS/ -- R01-GM32467/GM/NIGMS NIH HHS/ -- New York, N.Y. -- Science. 1984 Aug 31;225(4665):898-903.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/6206566" target="_blank"〉PubMed〈/a〉
    Keywords: Adenoviruses, Human/metabolism ; Base Sequence ; Chemical Phenomena ; Chemistry ; Nucleic Acid Conformation ; Nucleic Acid Precursors/analysis/*metabolism ; Oligoribonucleotides/metabolism ; Phosphates/metabolism ; RNA/analysis/*metabolism ; RNA Precursors ; *RNA Splicing ; RNA, Messenger/analysis/*metabolism ; RNA, Viral/analysis/*metabolism
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
    Published by American Association for the Advancement of Science (AAAS)
    Location Call Number Expected Availability
    BibTip Others were also interested in ...
    PAPER CURRENT
  • 12
    facet.materialart.
    Unknown
    beta-Carotene: an unusual type of lipid antioxidant (1984)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1984-05-11
    Description: The mechanism of lipid peroxidation and the manner in which antioxidants function is reviewed. beta-Carotene is a purported anticancer agent, which is believed by some to have antioxidant action of a radical-trapping type. However, definitive experimental support for such action has been lacking. New experiments in vitro show that beta-carotene belongs to a previously unknown class of biological antioxidants. Specifically, it exhibits good radical-trapping antioxidant behavior only at partial pressures of oxygen significantly less than 150 torr, the pressure of oxygen in normal air. Such low oxygen partial pressures are found in most tissues under physiological conditions. At higher oxygen pressures, beta-carotene loses its antioxidant activity and shows an autocatalytic, prooxidant effect, particularly at relatively high concentrations. Similar oxygen-pressure-dependent behavior may be shown by other compounds containing many conjugated double bonds.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Burton, G W -- Ingold, K U -- New York, N.Y. -- Science. 1984 May 11;224(4649):569-73.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/6710156" target="_blank"〉PubMed〈/a〉
    Keywords: Antioxidants/*metabolism ; Carotenoids/*metabolism ; Chemical Phenomena ; Chemistry ; Free Radicals ; Humans ; Linoleic Acids/metabolism ; *Lipid Metabolism ; Oxidation-Reduction ; Oxygen/metabolism ; Partial Pressure ; Peroxides/metabolism ; Tetrahydronaphthalenes/metabolism ; beta Carotene
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
    Published by American Association for the Advancement of Science (AAAS)
    Location Call Number Expected Availability
    BibTip Others were also interested in ...
    PAPER CURRENT
  • 13
    facet.materialart.
    Unknown
    Bromine residue at hydrophilic region influences biological activity of aplysiatoxin, a tumor promoter (1983)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1983-12-16
    Description: Aplysiatoxin and debromoaplysiatoxin, which are isolated from the seaweed, Lyngbya gracilis, differ in their chemical structure only by the presence or absence of a bromine residue in the hydrophilic region. The function and the structure-activity relation of the hydrophilic region are not known. Aplysiatoxin increased malignant transformation, stimulated DNA synthesis, and inhibited the binding of phorbol-12,13-dibutyrate and epidermal growth factor to cell receptors. Debromoaplysiatoxin inhibited the binding of these two substances as strongly as aplysiatoxin but did not increase malignant transformation or stimulate DNA synthesis. These results indicate that a slight change in the chemical structure of the hydrophilic region of aplysiatoxin affects its abilities to increase cell transformation and stimulate DNA synthesis and that the abilities of the tumor promoters to inhibit the binding of phorbol-12,13-dibutyrate and epidermal growth factor are dissociable from their abilities to increase cell transformation and stimulate DNA synthesis under some circumstances.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Shimomura, K -- Mullinix, M G -- Kakunaga, T -- Fujiki, H -- Sugimura, T -- New York, N.Y. -- Science. 1983 Dec 16;222(4629):1242-4.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/6316505" target="_blank"〉PubMed〈/a〉
    Keywords: Animals ; *Caenorhabditis elegans Proteins ; Carcinogens/*pharmacology ; Carrier Proteins ; Cell Line ; Cell Transformation, Neoplastic/*drug effects ; Chemical Phenomena ; Chemistry ; DNA/biosynthesis ; Epidermal Growth Factor/metabolism ; Lactones/analysis/*pharmacology ; *Lyngbya Toxins ; Mice ; Phorbol 12,13-Dibutyrate ; Phorbol Esters/metabolism ; *Protein Kinase C ; Receptor, Epidermal Growth Factor ; Receptors, Cell Surface/metabolism ; *Receptors, Drug ; Structure-Activity Relationship
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
    Published by American Association for the Advancement of Science (AAAS)
    Location Call Number Expected Availability
    BibTip Others were also interested in ...
    PAPER CURRENT
  • 14
    facet.materialart.
    Unknown
    Phenylalanine transfer RNA: molecular dynamics simulation (1984)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1984-03-16
    Description: Yeast phenylalanine transfer RNA was subjected to a 12-picosecond molecular dynamics simulation. The principal features of the x-ray crystallographic analysis are reproduced, and the amplitudes of atomic displacements appear to be determined by the degree of exposure of the atoms. An analysis of the hydrogen bonds shows a correlation between the average length of a bond and the fluctuation in that length and reveals a rocking motion of bases in Watson-Crick guanine X cytosine base pairs. The in-plane motions of the bases are generally of larger amplitude than the out-of-plane motions, and there are correlations in the motions of adjacent bases.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Harvey, S C -- Prabhakaran, M -- Mao, B -- McCammon, J A -- New York, N.Y. -- Science. 1984 Mar 16;223(4641):1189-91.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/6560785" target="_blank"〉PubMed〈/a〉
    Keywords: Chemical Phenomena ; Chemistry ; Computers ; Cytosine ; Guanine ; Hydrogen Bonding ; Nucleic Acid Conformation ; *RNA, Fungal ; *RNA, Transfer, Amino Acyl ; Yeasts/analysis
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
    Published by American Association for the Advancement of Science (AAAS)
    Location Call Number Expected Availability
    BibTip Others were also interested in ...
    PAPER CURRENT
  • 15
    facet.materialart.
    Unknown
    Reaction of the antitumor antibiotic CC-1065 with DNA: structure of a DNA adduct with DNA sequence specificity (1984)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1984-11-16
    Description: Sequence-dependent variations in DNA revealed by x-ray crystallographic studies have suggested that certain DNA-reactive drugs may react preferentially with defined sequences in DNA. Drugs that wind around the helix and reside within one of the grooves of DNA have perhaps the greatest chance of recognizing sequence-dependent features of DNA. The antitumor antibiotic CC-1065 covalently binds through N-3 of adenine and resides within the minor groove of DNA. This drug overlaps with five base pairs for which a high sequence specificity exists.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Hurley, L H -- Reynolds, V L -- Swenson, D H -- Petzold, G L -- Scahill, T A -- New York, N.Y. -- Science. 1984 Nov 16;226(4676):843-4.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/6494915" target="_blank"〉PubMed〈/a〉
    Keywords: Antibiotics, Antineoplastic/*metabolism ; *Base Sequence ; Binding Sites ; Chemical Phenomena ; Chemistry ; DNA/*metabolism ; *Indoles ; Leucomycins/*metabolism ; Molecular Conformation ; X-Ray Diffraction
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
    Published by American Association for the Advancement of Science (AAAS)
    Location Call Number Expected Availability
    BibTip Others were also interested in ...
    PAPER CURRENT
  • 16
    facet.materialart.
    Unknown
    Allylamine derivatives: new class of synthetic antifungal agents inhibiting fungal squalene epoxidase (1984)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1984-06-15
    Description: A new class of synthetic antifungal agents, the allylamines , has been developed by modification of naftifine , a topical antimycotic. SF 86-327, the most effective of these compounds so far, is highly active in vitro against a wide range of fungi and exceeds clinical standards in the oral and topical treatment of guinea pig dermatophytoses. SF 86-327 is a powerful specific inhibitor of fungal squalene epoxidase, a key enzyme in sterol biosynthesis.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Petranyi, G -- Ryder, N S -- Stutz, A -- New York, N.Y. -- Science. 1984 Jun 15;224(4654):1239-41.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/6547247" target="_blank"〉PubMed〈/a〉
    Keywords: Allylamine/analogs & derivatives/*chemical synthesis/pharmacology ; Amines/*chemical synthesis ; Animals ; Antifungal Agents/*chemical synthesis/pharmacology ; Chemical Phenomena ; Chemistry ; Dermatomycoses/drug therapy ; Fungi/*drug effects/enzymology ; Guinea Pigs ; Naphthalenes/chemical synthesis/pharmacology ; Oxygenases/*antagonists & inhibitors ; Squalene Monooxygenase
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
    Published by American Association for the Advancement of Science (AAAS)
    Location Call Number Expected Availability
    BibTip Others were also interested in ...
    PAPER CURRENT
  • 17
    facet.materialart.
    Unknown
    Disulfide bond engineered into T4 lysozyme: stabilization of the protein toward thermal inactivation (1984)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1984-11-02
    Description: By recombinant DNA techniques, a disulfide bond was introduced at a specific site in T4 lysozyme, a disulfide-free enzyme. This derivative retained full enzymatic activity and was more stable toward thermal inactivation than the wild-type protein. The derivative, T4 lysozyme (Ile3----Cys), was prepared by substituting a Cys codon for an Ile codon at position 3 in the cloned lysozyme gene by means of oligonucleotide-dependent, site-directed mutagenesis. The new gene was expressed in Escherichia coli under control of the (trp-lac) hybrid tac promoter, and the protein was purified. Mild oxidation generated a disulfide bond between the new Cys3 and Cys97, one of the two unpaired cysteines of the native molecule. Oxidized T4 lysozyme (Ile3----Cys) exhibited specific activity identical to that of the wild-type enzyme when measured at 20 degrees C in a cell-clearing assay. The cross-linked protein was more stable than the wild type during incubation at elevated temperatures as determined by recovered enzymatic activity at 20 degrees C.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Perry, L J -- Wetzel, R -- New York, N.Y. -- Science. 1984 Nov 2;226(4674):555-7.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/6387910" target="_blank"〉PubMed〈/a〉
    Keywords: Chemical Phenomena ; Chemistry ; DNA, Recombinant/metabolism ; Escherichia coli/enzymology ; *Genetic Engineering ; Kinetics ; Muramidase/*genetics/metabolism ; Protein Denaturation
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
    Published by American Association for the Advancement of Science (AAAS)
    Location Call Number Expected Availability
    BibTip Others were also interested in ...
    PAPER CURRENT
  • 18
    facet.materialart.
    Unknown
    DNA-binding proteins (1983)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1983-09-09
    Description: The structures of three proteins that regulate gene expression have been determined recently and suggest how these proteins may bind to their specific recognition sites on the DNA. One protein (Cro) is a repressor of gene expression, the second (CAP) usually stimulates gene expression, and the third (lambda repressor) can act as either a repressor or an activator. The three proteins contain a substructure consisting of two consecutive alpha helices that is virtually identical in each case. Structural and amino acid sequence comparisons suggest that this bihelical fold occurs in a number of proteins that regulate gene expression, and is an intrinsic part of the DNA-protein recognition event. The modes of repression and activation by Cro and lambda repressor are understood reasonably well, but the mode of action of CAP is still unclear.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Takeda, Y -- Ohlendorf, D H -- Anderson, W F -- Matthews, B W -- GM20066/GM/NIGMS NIH HHS/ -- GM28138/GM/NIGMS NIH HHS/ -- GM30894/GM/NIGMS NIH HHS/ -- New York, N.Y. -- Science. 1983 Sep 9;221(4615):1020-6.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/6308768" target="_blank"〉PubMed〈/a〉
    Keywords: Amino Acid Sequence ; Chemical Phenomena ; Chemistry ; *DNA Helicases ; DNA-Binding Proteins ; Escherichia coli/genetics ; Gene Expression Regulation ; Models, Chemical ; Protein Conformation
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
    Published by American Association for the Advancement of Science (AAAS)
    Location Call Number Expected Availability
    BibTip Others were also interested in ...
    PAPER CURRENT
  • 19
    facet.materialart.
    Unknown
    A nitrogen pressure of 50 atmospheres does not prevent evolution of hydrogen by nitrogenase (1984)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1984-06-08
    Description: The effect of a partial pressure of nitrogen of 50 atmospheres (5065 kilopascals ) on the hydrogen evolution reaction of nitrogenase has been investigated. Evolution of hydrogen was not blocked completely by 50 atmospheres of nitrogen in any of four experiments; rather, 27.3 +/- 2.4 percent of the total electron flux through nitrogenase was directed toward production of hydrogen. The ratio of hydrogen evolved to nitrogen fixed was close to 1:1, which implies that hydrogen evolution is obligatory in the fixation of molecular nitrogen by nitrogenase.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Simpson, F B -- Burris, R H -- AI-00848/AI/NIAID NIH HHS/ -- New York, N.Y. -- Science. 1984 Jun 8;224(4653):1095-7.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/6585956" target="_blank"〉PubMed〈/a〉
    Keywords: Chemical Phenomena ; Chemistry ; *Hydrogen ; *Nitrogen ; Nitrogen Fixation ; *Nitrogenase ; Partial Pressure
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
    Published by American Association for the Advancement of Science (AAAS)
    Location Call Number Expected Availability
    BibTip Others were also interested in ...
    PAPER CURRENT
  • 20
    facet.materialart.
    Unknown
    Nonvolatile mutagens in drinking water: production by chlorination and destruction by sulfite (1980)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1980-01-04
    Description: In concentrates of water produced in a laboratory simulation of a drinking water treatment process, direct-acting, nonvolatile mutagens were readily detected by means of the Ames Salmonella test. The mutagens were shown to be produced by the chlorination process. Treatment of the water with chloramine resulted in less mutagenic activity than treatment with free chlorine. Dechlorination of drinking water with sulfite sharply reduced the mutagenic activity. Treatment with sulfur dioxide is proposed as an effective, inexpensive method of reducing the direct-acting mutagenic activity of drinking water and of aqueous industrial effluents.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Cheh, A M -- Skochdopole, J -- Koski, P -- Cole, L -- New York, N.Y. -- Science. 1980 Jan 4;207(4426):90-2.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/6985746" target="_blank"〉PubMed〈/a〉
    Keywords: Chemical Phenomena ; Chemistry ; Chloramines ; Chlorine ; Mutagens/*analysis ; Salmonella typhimurium/genetics ; Sulfites ; Water Pollutants/*analysis ; Water Pollutants, Chemical/*analysis ; Water Supply/*analysis
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
    Published by American Association for the Advancement of Science (AAAS)
    Location Call Number Expected Availability
    BibTip Others were also interested in ...
    PAPER CURRENT
  • 21
    facet.materialart.
    Unknown
    Automated synthesis of gene fragments (1981)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1981-10-16
    Description: The DNA/RNA Synthesizer provides a complete and automated procedure for the synthesis of DNA sequences. Each base unit is added in a 30-minute cycle, permitting a tetradecamer to be constructed in 6 1/2 hours. The complete procedure is described, including a practical procedure for isolation and purification of the desired DNA sequence.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Alvarado-Urbina, G -- Sathe, G M -- Liu, W C -- Gillen, M F -- Duck, P D -- Bender, R -- Ogilvie, K K -- New York, N.Y. -- Science. 1981 Oct 16;214(4518):270-4.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/6169150" target="_blank"〉PubMed〈/a〉
    Keywords: Automation ; Chemical Phenomena ; Chemistry ; DNA/*chemical synthesis ; *Genes, Synthetic ; RNA/*chemical synthesis ; Solubility
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
    Published by American Association for the Advancement of Science (AAAS)
    Location Call Number Expected Availability
    BibTip Others were also interested in ...
    PAPER CURRENT
  • 22
    facet.materialart.
    Unknown
    Chitin: New facets of research (1981)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1981-05-15
    Description: Research on chitin as a marine resource is pointing to novel applications for this cellulose-like biopolymer. Discovery of nondegrading solvent systems has permitted the spinning of filaments, for example, for use as surgical sutures. New methods for preparing the bioactive alkyl glycoside of N-acetyl-D-glucosamine (the monomer unit of chitin) and a microcrystalline chitin has encouraged their use as promoters for growth of bifidobacteria and as an aid in digestion of high-lactose cheese whey by domestic animals. Chitin-protein complexes of several crustacean species show great variability in ratios of chitin to covalently bound protein and in residual protein in the "purified" chitins.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Austin, P R -- Brine, C J -- Castle, J E -- Zikakis, J P -- New York, N.Y. -- Science. 1981 May 15;212(4496):749-53.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/7221561" target="_blank"〉PubMed〈/a〉
    Keywords: Animal Feed ; Animals ; Cheese ; Chemical Phenomena ; Chemistry ; Chickens ; *Chitin ; Crystallography ; Lactose/metabolism ; Proteins/analysis ; Sutures ; *Technology
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
    Published by American Association for the Advancement of Science (AAAS)
    Location Call Number Expected Availability
    BibTip Others were also interested in ...
    PAPER CURRENT
  • 23
    facet.materialart.
    Unknown
    DNA sequencing and gene structure (1981)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1981-12-18
    Description: 〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Gilbert, W -- New York, N.Y. -- Science. 1981 Dec 18;214(4527):1305-12.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/7313687" target="_blank"〉PubMed〈/a〉
    Keywords: Base Sequence ; Chemical Phenomena ; Chemistry ; DNA/*genetics ; Eukaryotic Cells/physiology ; *Genes ; Hydrazines ; Lac Operon ; Methylation ; Prokaryotic Cells/physiology ; Sulfuric Acid Esters
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
    Published by American Association for the Advancement of Science (AAAS)
    Location Call Number Expected Availability
    BibTip Others were also interested in ...
    PAPER CURRENT
  • 24
    facet.materialart.
    Unknown
    Boradeption: a new procedure for transferring water-insoluble agents across cell membranes (1982)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1982-07-09
    Description: A new process has been developed which is called "Boradeption" to signify boronic acid--dependent phase transfer of water-insoluble agents. Highly fluorescent boronic acid dervatives, FluoroBoras, are solubilized with a physiologically compatible carrier buffer containing a receptor group for boronate adduct formation. The system can be used to stain living cells. In another variation of the Boradeption concept, an insoluble reporter molecule containing a boronate receptor is solubilized with a carrier buffer containing a boronic acid functional group. The boronate-receptor complexes, which are in dynamic equilibrium, can be designed as vital stains and reagents for a variety of biological and medical applications.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Gallop, P M -- Paz, M A -- Henson, E -- AG-00376-07/AG/NIA NIH HHS/ -- HL-20764-04A1/HL/NHLBI NIH HHS/ -- New York, N.Y. -- Science. 1982 Jul 9;217(4555):166-9.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/6178158" target="_blank"〉PubMed〈/a〉
    Keywords: Animals ; *Biological Transport ; *Boron Compounds/therapeutic use ; *Boronic Acids/therapeutic use ; *Cell Membrane Permeability ; Cells, Cultured ; Chemical Phenomena ; Chemistry ; Chromogenic Compounds/metabolism ; Cricetinae ; Fibroblasts ; Fluorescent Dyes/metabolism ; Humans ; Rats ; Staining and Labeling
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
    Published by American Association for the Advancement of Science (AAAS)
    Location Call Number Expected Availability
    BibTip Others were also interested in ...
    PAPER CURRENT
  • 25
    facet.materialart.
    Unknown
    Reversible chemical modification of the scrapie agent (1981)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1981-12-11
    Description: The scrapie agent causes a degenerative nervous system disease in sheep and goats. Studies with extensively purified preparations demonstrated that the agent contains a protein that is required for infectivity. Chemical modification of the scrapie agent by diethyl pyrocarbonate reduced the titer 1000-fold. Exposure of the inactivated agent to hydroxylamine, a strong nucleophile, resulted in complete restoration of infectivity. Presumably, nucleophilic residues within a scrapie agent protein undergo carbethoxylation on reaction with diethyl pyrocarbonate, and subsequent addition of hydroxylamine displaces these carbethoxy groups.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉McKinley, M P -- Masiarz, F R -- Prusiner, S B -- NS14069/NS/NINDS NIH HHS/ -- New York, N.Y. -- Science. 1981 Dec 11;214(4526):1259-61.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/6795721" target="_blank"〉PubMed〈/a〉
    Keywords: Animals ; Biological Assay ; Brain/microbiology ; Chemical Phenomena ; Chemistry ; Cricetinae ; Diethyl Pyrocarbonate/pharmacology ; Histidine/pharmacology ; *Prions ; Ribonucleases/pharmacology ; Serum Albumin, Bovine/pharmacology ; Viral Proteins/*isolation & purification/pharmacology
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
    Published by American Association for the Advancement of Science (AAAS)
    Location Call Number Expected Availability
    BibTip Others were also interested in ...
    PAPER CURRENT
  • 26
    facet.materialart.
    Unknown
    Nonenzymatic browning in vivo: possible process for aging of long-lived proteins (1981)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1981-01-30
    Description: The incubation of lens proteins with reducing sugars leads to the formation of fluorescent yellow pigments and cross-like similar to those reported in aging and cataractous human lenses. Called nonenzymatic browning or the Maillard reaction, this aging process also occurs in stored foods. Reducing sugars condense with the free amino group of proteins, then rearrange and dehydrate to form unsaturated pigments and cross-linked products. Although most proteins in living systems turn over with sufficient rapidity to avoid nonenzymatic browning, some, such as lens crystallins and skin collagen, are exceptionally long-lived and may be vulnerable.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Monnier, V M -- Cerami, A -- AM 19655/AM/NIADDK NIH HHS/ -- New York, N.Y. -- Science. 1981 Jan 30;211(4481):491-3.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/6779377" target="_blank"〉PubMed〈/a〉
    Keywords: *Aging ; Animals ; Cattle ; Chemical Phenomena ; Chemistry ; *Crystallins ; Diabetes Mellitus/physiopathology ; Glucose ; Glucosephosphates ; In Vitro Techniques ; Lysine ; *Proteins ; Spectrophotometry, Ultraviolet
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
    Published by American Association for the Advancement of Science (AAAS)
    Location Call Number Expected Availability
    BibTip Others were also interested in ...
    PAPER CURRENT
  • 27
    facet.materialart.
    Unknown
    The National Science Foundation looks to the future (1981)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1981-03-13
    Description: Great advances have been made in fundamental scientific research in recent years. The new knowledge gathered, in addition to deepening our understanding of the physical universe, contributes a range of abilities and opportunities to society that would not otherwise be available. Much research that may be called applied because it addresses needs of society is quite fundamental in character, and support of such research at the National Science Foundation is to be handled in tandem by the research directorates. Other areas that require a refocusing of support are engineering science and education, at all levels, in science and engineering. Increasing our strength in these areas is essential to achieve our national economic, social, and political goals. Steps are being taken by the National Science Foundation to make its structure better able to deal with engineering and applied research and to provide greater mutual reinforcement between applied and basic research.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Slaughter, J B -- New York, N.Y. -- Science. 1981 Mar 13;211(4487):1131-6.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/7466384" target="_blank"〉PubMed〈/a〉
    Keywords: Cell Biology ; Chemical Phenomena ; Chemistry ; *Forecasting ; Geological Phenomena ; Geology ; *Government Agencies ; Molecular Biology ; Neurochemistry ; Physical Phenomena ; Physics ; Research Support as Topic ; United States
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
    Published by American Association for the Advancement of Science (AAAS)
    Location Call Number Expected Availability
    BibTip Others were also interested in ...
    PAPER CURRENT
  • 28
    facet.materialart.
    Unknown
    New chemistry of an old molecule: cis-[Pt(NH3)2Cl2] (1982)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1982-12-10
    Description: The discovery that cis-diamminedichloroplatinum(II) (cis-DDP) has clinically useful antitumor properties and can form platinum blues spawned an extensive investigation of its chemistry in water. Several new molecules have been synthesized, some rather old ones have been characterized for the first time, and clues have begun to emerge about the chemical interaction of cis-DDP with its likely biological target, DNA.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Lippard, S J -- New York, N.Y. -- Science. 1982 Dec 10;218(4577):1075-82.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/6890712" target="_blank"〉PubMed〈/a〉
    Keywords: Chemical Phenomena ; Chemistry ; *Cisplatin ; *Dna ; Hydrolysis ; Pigments, Biological
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
    Published by American Association for the Advancement of Science (AAAS)
    Location Call Number Expected Availability
    BibTip Others were also interested in ...
    PAPER CURRENT
  • 29
    facet.materialart.
    Unknown
    The chemistry of vision (1982)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1982-12-03
    Description: The visual response is initiated by light reception and transduction into chemical and electrical energy in the outer-segment membranes of rod and cone cells. Recent research on the molecular events controlled by light has clarified the roles of some of the rod outer-segment biomolecules. These developments and the current unresolved questions are described.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉O'Brien, D F -- New York, N.Y. -- Science. 1982 Dec 3;218(4576):961-6.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/6291153" target="_blank"〉PubMed〈/a〉
    Keywords: Animals ; Blood Proteins/metabolism ; Calcium/metabolism ; Chemical Phenomena ; Chemistry ; Enzyme Activation ; Enzymes/metabolism ; GTP-Binding Proteins ; Light ; Membranes/metabolism ; Models, Biological ; Phosphoric Diester Hydrolases/biosynthesis ; Photoreceptor Cells/*metabolism ; Receptors, Cell Surface/metabolism ; Rhodopsin/metabolism ; Rod Cell Outer Segment/*metabolism ; Vision, Ocular/*physiology
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
    Published by American Association for the Advancement of Science (AAAS)
    Location Call Number Expected Availability
    BibTip Others were also interested in ...
    PAPER CURRENT
  • 30
    facet.materialart.
    Unknown
    Antiviral agents (1983)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1983-06-10
    Description: 〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Krenitsky, T A -- Beauchamp, L -- New York, N.Y. -- Science. 1983 Jun 10;220(4602):1106.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/6857236" target="_blank"〉PubMed〈/a〉
    Keywords: Acyclovir/metabolism ; *Antiviral Agents/metabolism ; Chemical Phenomena ; Chemistry ; Humans ; Vidarabine/metabolism
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
    Published by American Association for the Advancement of Science (AAAS)
    Location Call Number Expected Availability
    BibTip Others were also interested in ...
    PAPER CURRENT
  • 31
    facet.materialart.
    Unknown
    Metastable species of hemoglobin: room temperature transients and cryogenically trapped intermediates (1983)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1983-05-06
    Description: Resonance Raman spectra of photolyzed carbonmonoxyhemoglobin obtained with 10-nanosecond pulses are compared with the spectra of photolyzed carbonmonoxyhemoglobin stabilized at 80 K. In comparing the deoxy with the photodissociated species, the changes in the Raman spectra are the same for these two experimental regimes. These results show that at ambient and cryogenic temperatures the heme pocket in liganded hemoglobin is significantly different from that of deoxyhemoglobin. It is concluded that measurements of the properties of intermediate species from photodissociated hemoglobin stabilized at low temperatures can be used to probe the short-lived metastable forms of hemoglobin present after photodissociation under biologically relevant solution conditions.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Ondrias, M R -- Friedman, J M -- Rousseau, D L -- New York, N.Y. -- Science. 1983 May 6;220(4597):615-7.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/6836305" target="_blank"〉PubMed〈/a〉
    Keywords: Carboxyhemoglobin ; Chemical Phenomena ; Chemistry ; Freezing ; *Hemoglobins ; Humans ; Ligands ; Spectrum Analysis, Raman ; Temperature
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
    Published by American Association for the Advancement of Science (AAAS)
    Location Call Number Expected Availability
    BibTip Others were also interested in ...
    PAPER CURRENT
  • 32
    facet.materialart.
    Unknown
    Irreversible ligands with high selectivity toward delta and mu opiate receptors (1983)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1983-04-15
    Description: Alkylating agents that display strong selectivity for opiate receptor types delta or mu were prepared by appropriate modification of the structures of the strong analgesics fentanyl, etonitazene, and endoethenotetrahydrooripavine. The availability of these substances should facilitate studies of the structural basis of receptor specificity and of the physiologic roles of these receptors.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Rice, K C -- Jacobson, A E -- Burke, T R Jr -- Bajwa, B S -- Streaty, R A -- Klee, W A -- New York, N.Y. -- Science. 1983 Apr 15;220(4594):314-6.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/6132444" target="_blank"〉PubMed〈/a〉
    Keywords: Alkylation ; Animals ; Benzimidazoles/analogs & derivatives/metabolism ; Brain/physiology ; Cells, Cultured ; Chemical Phenomena ; Chemistry ; Enkephalin, Methionine/analogs & derivatives/metabolism ; Fentanyl/analogs & derivatives/metabolism ; *Isothiocyanates ; Ligands ; Rats ; Receptors, Opioid/*metabolism/physiology ; Thebaine/analogs & derivatives/pharmacology
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
    Published by American Association for the Advancement of Science (AAAS)
    Location Call Number Expected Availability
    BibTip Others were also interested in ...
    PAPER CURRENT
  • 33
    facet.materialart.
    Unknown
    Trace chemistries of fire: a source of chlorinated dioxins (1980)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1980-10-01
    Description: 〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Bumb, R R -- Crummett, W B -- Cutie, S S -- Gledhill, J R -- Hummel, R H -- Kagel, R O -- Lamparski, L L -- Luoma, E V -- Miller, D L -- Nestrick, T J -- Shadoff, L A -- Stehl, R H -- Woods, J S -- New York, N.Y. -- Science. 1980 Oct;210(4468):385-90.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/6159682" target="_blank"〉PubMed〈/a〉
    Keywords: Air Pollutants/analysis ; Chemical Phenomena ; Chemistry ; Chromatography, High Pressure Liquid ; *Dioxins/analysis ; *Fires ; Power Plants ; Smoke/analysis ; Soil Pollutants/analysis ; Tetrachlorodibenzodioxin/analysis ; Vehicle Emissions/analysis ; Water Pollutants, Chemical/analysis
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
    Published by American Association for the Advancement of Science (AAAS)
    Location Call Number Expected Availability
    BibTip Others were also interested in ...
    PAPER CURRENT
  • 34
    facet.materialart.
    Unknown
    Synthetic competitive antagonists of corticotropin-releasing factor: effect on ACTH secretion in the rat (1984)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1984-05-25
    Description: Polypeptide analogs of the known members of the corticotropin-releasing factor (CRF) family were synthesized and tested in vitro and in vivo for enhanced potency or competitive antagonism. Predictive methods and physicochemical measurements had suggested an internal secondary alpha-helical conformation spanning about 25 residues for at least three members of the CRF family. Maximization of alpha-helix-forming potential by amino acid substitutions from the native known sequences (rat/human and ovine CRF, sauvagine, and carp and sucker urotensin 1) led to the synthesis of an analog that was found to be more than twice as potent as either of the parent peptides in vitro. In contrast, certain amino-terminally shortened fragments, such as alpha-helical CRF or ovine CRF residues 8 to 41, 9 to 41, and 10 to 41, were found to be competitive inhibitors in vitro. Selected antagonists were examined and also found to be active in vivo.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Rivier, J -- Rivier, C -- Vale, W -- AA03504/AA/NIAAA NIH HHS/ -- AM20917/AM/NIADDK NIH HHS/ -- AM26741/AM/NIADDK NIH HHS/ -- etc. -- New York, N.Y. -- Science. 1984 May 25;224(4651):889-91.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/6326264" target="_blank"〉PubMed〈/a〉
    Keywords: Adrenocorticotropic Hormone/secretion ; Animals ; Binding, Competitive ; Chemical Phenomena ; Chemistry ; Corticotropin-Releasing Hormone/*antagonists & inhibitors ; Rats
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
    Published by American Association for the Advancement of Science (AAAS)
    Location Call Number Expected Availability
    BibTip Others were also interested in ...
    PAPER CURRENT
  • 35
    facet.materialart.
    Unknown
    THE MERCURY CAPSULE ATTITUDE CONTROL SYSTEM (1962)
    In:  CASI
    Details
    Publication Date: 2009-12-22
    Description: Mercury capsule attitude control system
    Keywords: SPACE VEHICLES
    Type: Proceedings of the National Meeting on Manned Space Flight: Unclassified Portion
    Format: text
    Location Call Number Expected Availability
    BibTip Others were also interested in ...
    NASA TECHNICAL REPORTS
  • 36
    facet.materialart.
    Unknown
    SPACE VEHICLE ATTITUDE STABILIZATION USING PULSE-MODULATED JET CONTROL (1961)
    In:  CASI
    Details
    Publication Date: 2008-08-25
    Description: Space vehicle attitude stabilization using pulse modulated jet control
    Keywords: SPACE VEHICLES
    Type: MTP-M-G&C-61-32
    Format: text
    Location Call Number Expected Availability
    BibTip Others were also interested in ...
    NASA TECHNICAL REPORTS
  • 37
    facet.materialart.
    Unknown
    Spacecraft (1964)
    In:  CASI
    Details
    Publication Date: 2011-10-14
    Description: Micrometeoroid satellite Explorer XIII - vehicle and launch
    Keywords: SPACE VEHICLES
    Format: text
    Location Call Number Expected Availability
    BibTip Others were also interested in ...
    NASA TECHNICAL REPORTS
  • 38
    facet.materialart.
    Unknown
    Composite systems utilization for space shuttle structures (1972)
    In:  CASI
    Details
    Publication Date: 2005-11-30
    Description: Research and development of composite material systems to show applicability of these materials to shuttle structures and to demonstrate availability through a hardware development program is reported. The various configurations studied and potential areas of composite structures use are described and an outline of ongoing composite programs, complementing the indicated feasible applications, including a typical cost study, is shown. The following composite systems are investigated: Boron filaments with epoxy, polyimide, or aluminum matrix, and graphite filaments with epoxy or polyimide matrix.
    Keywords: SPACE VEHICLES
    Type: NASA Space Shuttle Technol. Conf.; p 605-644
    Format: text
    Location Call Number Expected Availability
    BibTip Others were also interested in ...
    NASA TECHNICAL REPORTS
  • 39
    facet.materialart.
    Unknown
    Flight loads and control (1972)
    In:  CASI
    Details
    Publication Date: 2005-11-30
    Description: The prediction of flight loads and their potential reduction, using various control logics for the space shuttle vehicles, is very complex. Some factors, not found on previous launch vehicles, that increase the complexity are large lifting surfaces, unsymmetrical structure, unsymmetrical aerodynamics, trajectory control system coupling, and large aeroelastic effects. Discussed are these load producing factors and load reducing techniques. Identification of potential technology areas is included.
    Keywords: SPACE VEHICLES
    Type: NASA Space Shuttle Technol. Conf.; p 175-203
    Format: text
    Location Call Number Expected Availability
    BibTip Others were also interested in ...
    NASA TECHNICAL REPORTS
  • 40
    facet.materialart.
    Unknown
    New considerations for pogo prevention on space shuttle (1972)
    In:  CASI
    Details
    Publication Date: 2005-11-30
    Description: Recommendations for improving the methodology of pogo suppression for the space shuttle include: Consideration of inter-pump location for accumulator or active device, inclusion of tank outflow effects in dynamic structural analysis, the use of simplified transfer functions in systems studies, three phase dynamic testing program for turbopump with development of dynamic flowmeters, and the use of a linearized mathematical model for engine physics studies.
    Keywords: SPACE VEHICLES
    Type: NASA, Washington NASA Space Shuttle Technol. Conf.; p 97-116
    Format: text
    Location Call Number Expected Availability
    BibTip Others were also interested in ...
    NASA TECHNICAL REPORTS
  • 41
    facet.materialart.
    Unknown
    Development of methods for fracture control of space shuttle structures (1972)
    In:  CASI
    Details
    Publication Date: 2005-11-30
    Description: The technology with respect to fracture control requirements of the shuttle is considered. The current state-of-the-art does permit an approach based on linear elastic fracture mechanics concepts. Development and implementation of a fracture control plan should recognize deficiencies and provide adequate resources for the extensive empirical test data which are required. With respect to the cost impact of such tests, recent experiences involving advanced aircraft systems have seen unit cost increases of from 200 to 500 percent.
    Keywords: SPACE VEHICLES
    Type: NASA Space Shuttle Technol. Conf.; p 727-770
    Format: text
    Location Call Number Expected Availability
    BibTip Others were also interested in ...
    NASA TECHNICAL REPORTS
  • 42
    facet.materialart.
    Unknown
    Docking devices for Soyuz-type spacecraft (1972)
    In:  CASI
    Details
    Publication Date: 2005-11-30
    Description: Two docking device designs for Soyuz-type spacecraft are compared. The first was flight tested successfully; the second achieves rigid and exact joining of two spacecraft, while incorporating changes to allow for the intravehicular transfer of crew members. The main functions of the docking device are considered, with the means by which they are accomplished, and measures for increasing its reliability and flexibility in service are noted.
    Keywords: SPACE VEHICLES
    Type: 6th Aerospace Mech. Symp.; p 143-150
    Format: text
    Location Call Number Expected Availability
    BibTip Others were also interested in ...
    NASA TECHNICAL REPORTS
  • 43
    facet.materialart.
    Unknown
    Aerospace transporter and lifting body activities in Europe and potential participation in the development of the space shuttle orbiter (1972)
    In:  CASI
    Details
    Publication Date: 2005-11-30
    Description: The course of European aerospace research regarding reentry problems is briefly reviewed for the period from 1966 up to the present. The considerable experience gained by Europe, and particularly Germany, is shown to have led to their involvement and participation in the U.S. space shuttle program. The areas of investigation and expected contributions by European cooperation in the shuttle program are outlined.
    Keywords: SPACE VEHICLES
    Type: NASA. Langley Res. Center Space Shuttle Aerothermodyn. Technol. Conf., vol. 3; p 969-995
    Format: text
    Location Call Number Expected Availability
    BibTip Others were also interested in ...
    NASA TECHNICAL REPORTS
  • 44
    facet.materialart.
    Unknown
    Development of payload subsystem-primate mission-Biosatellite program (1971)
    In:  CASI
    Details
    Publication Date: 2005-11-30
    Description: Design and operation of the primate life support subsystem for the Biosatellite Program as used during the flight of Biosatellite 3 are discussed. Included are preflight changes necessitated by the primate's (a Macaca nemistrina monkey) influence on the initial equipment design.
    Keywords: SPACE VEHICLES
    Type: NASA. Goddard Space Flight Center 5th Aerospace Mech. Symp.; p 177-183
    Format: text
    Location Call Number Expected Availability
    BibTip Others were also interested in ...
    NASA TECHNICAL REPORTS
  • 45
    facet.materialart.
    Unknown
    Docking-mechanism attenuator with electromechanical damper (1971)
    In:  CASI
    Details
    Publication Date: 2005-11-30
    Description: Theoretical and practical problems involved in the application of electromechanical damping for spacecraft docking-mechanism attenuation are discussed. Some drawbacks of hydraulic dampers used for the purpose are pointed out. The basic scheme of the attenuator with the electromechanical damper is given.
    Keywords: SPACE VEHICLES
    Type: NASA. Goddard Space Flight Center 5th Aerospace Mech. Symp.; p 43-57
    Format: text
    Location Call Number Expected Availability
    BibTip Others were also interested in ...
    NASA TECHNICAL REPORTS
  • 46
    facet.materialart.
    Unknown
    The importance of nondestructive testing for the coated metallic thermal protection system (1970)
    In:  CASI
    Details
    Publication Date: 2005-11-27
    Description: Nondestructive testing techniques for coated metallic thermal protection system for space shuttles
    Keywords: SPACE VEHICLES
    Type: NASA. LEWIS RES. CENTER SPACE TRANSPORTATION SYSTEM TECHNOL. SYMP., VOL. 3 JUL. 1970; P 261-272
    Format: text
    Location Call Number Expected Availability
    BibTip Others were also interested in ...
    NASA TECHNICAL REPORTS
  • 47
    facet.materialart.
    Unknown
    Materials reuse, evaluation, inspection and repair (1970)
    In:  CASI
    Details
    Publication Date: 2005-11-27
    Description: Properties, evaluation, inspection, and repair of alloys and silicide coatings for space shuttles
    Keywords: SPACE VEHICLES
    Type: SPACE TRANSPORTATION SYSTEM TECHNOL. SYMP., VOL. 3 JUL. 1970; P 247-260
    Format: text
    Location Call Number Expected Availability
    BibTip Others were also interested in ...
    NASA TECHNICAL REPORTS
  • 48
    facet.materialart.
    Unknown
    Temperature control for the space shuttle (1970)
    In:  CASI
    Details
    Publication Date: 2005-11-27
    Description: Temperature control system for space shuttles
    Keywords: SPACE VEHICLES
    Type: NASA. LEWIS RES. CENTER SPACE TRANSPORTATION SYSTEM TECHNOL. SYMP., VOL. 3 JUL. 1970; P 201-207
    Format: text
    Location Call Number Expected Availability
    BibTip Others were also interested in ...
    NASA TECHNICAL REPORTS
  • 49
    facet.materialart.
    Unknown
    Space shuttle structural fatigue considerations (1970)
    In:  CASI
    Details
    Publication Date: 2005-11-27
    Description: Space shuttle structural fatigue analysis
    Keywords: SPACE VEHICLES
    Type: NASA. LEWIS RES. CENTER SPACE TRANSPORTATION SYSTEM TECHNOL. SYMP., VOL. 3 JUL. 1970; P 33-47
    Format: text
    Location Call Number Expected Availability
    BibTip Others were also interested in ...
    NASA TECHNICAL REPORTS
  • 50
    facet.materialart.
    Unknown
    Structural design technology - Introduction and overview (1970)
    In:  CASI
    Details
    Publication Date: 2005-11-27
    Description: NASA plan for development of space shuttle structural design technology
    Keywords: SPACE VEHICLES
    Type: SPACE TRANSPORTATION SYSTEM TECHNOL. SYMP., VOL. 3 JUL. 1970; P 9-16
    Format: text
    Location Call Number Expected Availability
    BibTip Others were also interested in ...
    NASA TECHNICAL REPORTS
  • 51
    facet.materialart.
    Unknown
    Problems of atmospheric entry (1971)
    In:  CASI
    Details
    Publication Date: 2005-11-27
    Description: Aerodynamic and heating problems of spacecraft entry into Mars and Venus atmospheres
    Keywords: SPACE VEHICLES
    Type: PERFORMANCE AND DYN. OF AEROSPACE VEHICLES 1971; P 175-288
    Format: text
    Location Call Number Expected Availability
    BibTip Others were also interested in ...
    NASA TECHNICAL REPORTS
  • 52
    facet.materialart.
    Unknown
    Space shuttle acoustics (1971)
    In:  CASI
    Details
    Publication Date: 2005-11-27
    Description: Farfield and nearfield acoustic environments of space shuttle
    Keywords: SPACE VEHICLES
    Type: NASA SPACE SHUTTLE TECHNOL. CONF., VOL. 3 APR. 1971; P 401-422
    Format: text
    Location Call Number Expected Availability
    BibTip Others were also interested in ...
    NASA TECHNICAL REPORTS
  • 53
    facet.materialart.
    Unknown
    Shuttle pogo review (1971)
    In:  CASI
    Details
    Publication Date: 2005-11-27
    Description: Results of pogo stability analyses
    Keywords: SPACE VEHICLES
    Type: NASA SPACE SHUTTLE TECHNOL. CONF., VOL. 3 APR. 1971; P 359-399
    Format: text
    Location Call Number Expected Availability
    BibTip Others were also interested in ...
    NASA TECHNICAL REPORTS
  • 54
    facet.materialart.
    Unknown
    Effects of space shuttle configuration on wing buffet and flutter. Part 1 - Launch vehicle with tip fin (1971)
    In:  CASI
    Details
    Publication Date: 2005-11-27
    Description: Influence of space shuttle configurations on wing aeroelastic behavior
    Keywords: SPACE VEHICLES
    Type: NASA SPACE SHUTTLE TECHNOL. CONF., VOL. 3 APR. 1971; P 181-199
    Format: text
    Location Call Number Expected Availability
    BibTip Others were also interested in ...
    NASA TECHNICAL REPORTS
  • 55
    facet.materialart.
    Unknown
    Recent studies of effects of ground winds on space shuttle vehicles (1971)
    In:  CASI
    Details
    Publication Date: 2005-11-27
    Description: Studying ground-wind loads with models of space shuttle configurations to assess aerodynamic instabilities on erected space shuttle vehicles
    Keywords: SPACE VEHICLES
    Type: NASA SPACE SHUTTLE TECHNOL. CONF., VOL. 3 APR. 1971; P 155-179
    Format: text
    Location Call Number Expected Availability
    BibTip Others were also interested in ...
    NASA TECHNICAL REPORTS
  • 56
    facet.materialart.
    Unknown
    Some landing gear considerations for space shuttle vehicles (1971)
    In:  CASI
    Details
    Publication Date: 2005-11-27
    Description: Criteria for designing space shuttle landing systems
    Keywords: SPACE VEHICLES
    Type: NASA SPACE SHUTTLE TECHNOL. CONF., VOL. 3 APR. 1971; P 121-154
    Format: text
    Location Call Number Expected Availability
    BibTip Others were also interested in ...
    NASA TECHNICAL REPORTS
  • 57
    facet.materialart.
    Unknown
    Acoustic environment characteristics of the space shuttle (1970)
    In:  CASI
    Details
    Publication Date: 2005-11-27
    Description: Space shuttle acoustic environment characteristics and plume induced flow separation phenomenon
    Keywords: SPACE VEHICLES
    Type: SPACE TRANSPORTATION SYSTEM TECHNOL. SYMP., VOL. 2 JUL. 1970; P 285-300
    Format: text
    Location Call Number Expected Availability
    BibTip Others were also interested in ...
    NASA TECHNICAL REPORTS
  • 58
    facet.materialart.
    Unknown
    Trajectory and performance (1970)
    In:  CASI
    Details
    Publication Date: 2005-11-27
    Description: Trajectory and performance of Agena-Nimbus 3 satellite
    Keywords: SPACE VEHICLES
    Type: THORAD-AGENA PERFORMANCE FOR THE ~NIMBUS 3 MISSION JUN. 1970; P 13-19
    Format: text
    Location Call Number Expected Availability
    BibTip Others were also interested in ...
    NASA TECHNICAL REPORTS
  • 59
    facet.materialart.
    Unknown
    Development of the ideas of K. E. Tsiolkovskiy concerning 'rocket trains' in the transactions of Soviet and foreign scientists (1970)
    In:  CASI
    Details
    Publication Date: 2005-11-27
    Description: Mass ratio allowances for mathematical modeling of optimal multistage rocket vehicles
    Keywords: SPACE VEHICLES
    Type: TRANS. OF THE FIRST LECTURES DEDICATED TO THE DEVELOP. OF THE SCI. HERITAGE OF K. E. TSIOLKOVSKIY APR. 1970; P 27-41
    Format: text
    Location Call Number Expected Availability
    BibTip Others were also interested in ...
    NASA TECHNICAL REPORTS
  • 60
    facet.materialart.
    Unknown
    Status of reusable surface insulation thermal protection system technology programs (1972)
    In:  CASI
    Details
    Publication Date: 2005-11-30
    Description: The development of three low-density rigidized insulation materials for the shuttle TPS application is reported. These materials consist of one high purity silica system and two systems based on mullite, an aluminum silicate. Both systems consist of fibers joined together with appropriate binders to obtain a rigidized insulation composite. Both material systems require the application of a glassy coating to provide a wear resistant, high emittance surface and to prevent the absorption of water by the fiber matrix. The technology program has addressed the development of water impervious coatings, methods of assembling the materials in design concepts while minimizing the thermal stress in the insulation, achieving compatibility between the RSI material and the structural system, and test evaluations to demonstrate the feasibility of the surface insulation concept.
    Keywords: SPACE VEHICLES
    Type: NASA Space Shuttle Technol. Conf.; p 435-474
    Format: text
    Location Call Number Expected Availability
    BibTip Others were also interested in ...
    NASA TECHNICAL REPORTS
  • 61
    facet.materialart.
    Unknown
    Overview of technology relative to the pogo instability on space shuttle (1972)
    In:  CASI
    Details
    Publication Date: 2005-11-30
    Description: The prediction of pogo contains a major source of uncertainty in the difficulty of defining the dynamic characteristics of certain components. An overview of the space shuttle technology with respect to each the following pogo problem areas is presented: structure, tank-liquid interaction, feedline, engine (pump), pogo-loop/control-loop interaction, and stability analysis.
    Keywords: SPACE VEHICLES
    Type: NASA Space Shuttle Technol. Conf.; p 117-138
    Format: text
    Location Call Number Expected Availability
    BibTip Others were also interested in ...
    NASA TECHNICAL REPORTS
  • 62
    facet.materialart.
    Unknown
    Assessment of potential buffet problems on the space shuttle vehicle (1972)
    In:  CASI
    Details
    Publication Date: 2005-11-30
    Description: Buffet of the space shuttle launch and reentry configuration is an area requiring continued evaluation to produce a safe reliable vehicle of minimum weight. Buffet forces result from flow separation and therefore can not be predicted accurately. Buffet loads are highly sensitive to configuration, angle of attack, and Mach number and can be reliably determined only by wind tunnel tests of elastically scaled models.
    Keywords: SPACE VEHICLES
    Type: NASA Space Shuttle Technol. Conf.; p 25-43
    Format: text
    Location Call Number Expected Availability
    BibTip Others were also interested in ...
    NASA TECHNICAL REPORTS
  • 63
    facet.materialart.
    Unknown
    Dynamic analysis for shuttle design verification (1972)
    In:  CASI
    Details
    Publication Date: 2005-11-30
    Description: Two approaches that are used for determining the modes and frequencies of space shuttle structures are discussed. The first method, direct numerical analysis, involves finite element mathematical modeling of the space shuttle structure in order to use computer programs for dynamic structural analysis. The second method utilizes modal-coupling techniques of experimental verification made by vibrating only spacecraft components and by deducing modes and frequencies of the complete vehicle from results obtained in the component tests.
    Keywords: SPACE VEHICLES
    Type: NASA Space Shuttle Technol. Conf.; p 205-230
    Format: text
    Location Call Number Expected Availability
    BibTip Others were also interested in ...
    NASA TECHNICAL REPORTS
  • 64
    facet.materialart.
    Unknown
    Surface studies on Surveyor 3 tubing sections (1972)
    In:  CASI
    Details
    Publication Date: 2005-11-30
    Description: Sections C and E of the unpainted, polished aluminum tubing from the strut of the radar altimeter and Doppler velocity sensor were examined in a transmission electron microscope for micrometeorite damage and ion bombardment. Both sections were contaminated and eroded on one side; it is suggested that these conditions were caused by sandblasting by lunar dust and retrorocket plume contamination during Surveyor 3 landing. Microcraters of different configurations were found on the bright sides of the tubes. Several degrees of violence were involved in the formation of the craters, and the particle size could be responsible for some differences. All micropits found were on the bright areas and data indicate 0.2 hypervelocity impact/sq cm and 2/sq cm for other types of craters. The greatest degree of damage resulted from particle impact and was limited to a maximum depth of 2 microns.
    Keywords: SPACE VEHICLES
    Type: NASA, Washington Analysis of Surveyor 3 Mater. and Phot. Returned by Apollo 12; p 154-158
    Format: text
    Location Call Number Expected Availability
    BibTip Others were also interested in ...
    NASA TECHNICAL REPORTS
  • 65
    facet.materialart.
    Unknown
    Aerodynamic studies of delta-wing shuttle orbiters. Part 2: Hypersonics (1972)
    In:  CASI
    Details
    Publication Date: 2005-11-30
    Description: An early version of an external hydrogen-oxygen tank orbiter was used as a baseline vehicle to experimentally evaluate: (1) nose shape and canopy effects on longitudinal, lateral, and directional stability and trim, and (2) yaw due to aerodynamic roll control at hypersonic speeds. Nose alterations were examined since that part of the vehicle may be subject to modifications because of internal packaging requirements, alleviation of potential high heating areas, and/or possible improvements in aerodynamic stability and control. There was also some concern about the effect of the rather high profile canopy on the aerodynamics; therefore its removal was examined. In addition, roll-yaw coupling was investigated because of its impact on the RCS fuel requirements for entry maneuvers.
    Keywords: SPACE VEHICLES
    Type: Space Shuttle Aerothermodyn. Technol. Conf., vol. 3; p 803-830
    Format: text
    Location Call Number Expected Availability
    BibTip Others were also interested in ...
    NASA TECHNICAL REPORTS
  • 66
    facet.materialart.
    Unknown
    Impact of subsonic aerodynamic considerations on a space shuttle booster configuration (1972)
    In:  CASI
    Details
    Publication Date: 2005-11-30
    Description: Considerations of cruise-back efficiency and subsonic flying qualities are shown to have resulted in a configuration with an aft high wing of moderate aspect ratio and with vertical tails located at the wing tips. The need to protect the air breathing engines during ascent and reentry and the desire for a low trim penalty longitudinal control surface led to consideration of a jet-flap canard. The advantages of this application of STOL technology to a space system are examined and the results of both wind tunnel tests and flight simulations are discussed. Since the use of the jet-flap canard concept offers the potential for a minimum weight vehicle, a proposed technology development program is outlined in order that the full benefit of this concept may be realized.
    Keywords: SPACE VEHICLES
    Type: NASA. Langley Res. Center Space Shuttle Aerothermodyn. Technol. Conf., vol.3; p 737-784
    Format: text
    Location Call Number Expected Availability
    BibTip Others were also interested in ...
    NASA TECHNICAL REPORTS
  • 67
    facet.materialart.
    Unknown
    On the possibility of Earth reentry simulation of shallow angle Jupiter entry (1972)
    In:  CASI
    Details
    Publication Date: 2005-11-30
    Description: Possible Earth reentry simulation of shallow-angle (3 to 30 deg) Jupiter entry was investigated in terms of four parameters of the bow shock layer ahead of a blunt vehicle: peak (equilibrium) temperature, peak pressure, peak inward radiative flux, and time-integrated radiative flux. It is shown that simulation ranging from fair to good can be achieved. Reentry is easiest (lowest Earth reentry speed) at steep Earth reentry, in the Earth entry speed range of 15 to 22 km/sec, for both the Jupiter nominal and cool atmospheres. Increased Earth speed is required, generally, for increasing Jupiter entry angle, and for increasing temperature, radiative flux, time-integrated flux and pressure, in that order.
    Keywords: SPACE VEHICLES
    Type: JPL Quart. Tech. Rev., Vol. 1, No. 4; p 19-29
    Format: text
    Location Call Number Expected Availability
    BibTip Others were also interested in ...
    NASA TECHNICAL REPORTS
  • 68
    facet.materialart.
    Unknown
    Materials properties and allowables for the space shuttle (1970)
    In:  CASI
    Details
    Publication Date: 2005-11-27
    Description: Space shuttle materials properties and allowables
    Keywords: SPACE VEHICLES
    Type: NASA. LEWIS RES. CENTER SPACE TRANSPORTATION SYSTEM TECHNOL. SYMP., VOL. 3 JUL. 1970; P 273-287
    Format: text
    Location Call Number Expected Availability
    BibTip Others were also interested in ...
    NASA TECHNICAL REPORTS
  • 69
    facet.materialart.
    Unknown
    Thermal protection systems - Introduction and overview (1970)
    In:  CASI
    Details
    Publication Date: 2005-11-27
    Description: Space shuttle thermal protection systems technology program summary
    Keywords: SPACE VEHICLES
    Type: SPACE TRANSPORTATION SYSTEM TECHNOL. SYMP., VOL. 3 JUL. 1970; P 139-144
    Format: text
    Location Call Number Expected Availability
    BibTip Others were also interested in ...
    NASA TECHNICAL REPORTS
  • 70
    facet.materialart.
    Unknown
    The development of effective fracture control procedures for space shuttle (1970)
    In:  CASI
    Details
    Publication Date: 2005-11-27
    Description: Structural fracture causes and control procedures for space shuttles
    Keywords: SPACE VEHICLES
    Type: NASA. LEWIS RES. CENTER SPACE TRANSPORTATION SYSTEM TECHNOL. SYMP., VOL. 3 JUL. 1970; P 49-60
    Format: text
    Location Call Number Expected Availability
    BibTip Others were also interested in ...
    NASA TECHNICAL REPORTS
  • 71
    facet.materialart.
    Unknown
    Orbiting astronomical observatory mission operations (1970)
    In:  CASI
    Details
    Publication Date: 2005-11-27
    Description: Stabilization and control system and mission operations for OAO
    Keywords: SPACE VEHICLES
    Type: OPT. TELESCOPE TECHNOL. 1970; P 635-643
    Format: text
    Location Call Number Expected Availability
    BibTip Others were also interested in ...
    NASA TECHNICAL REPORTS
  • 72
    facet.materialart.
    Unknown
    Application of composite materials to space shuttle tanks (1972)
    In:  CASI
    Details
    Publication Date: 2005-11-30
    Description: Tanks are broken down into two categories: pressure vessels that carry primarily pressure loads, and structural tanks that carry structural loads such as thrust or bending in addition to pressure. A significant portion of the shuttle orbiter structure are tanks and in order to minimize both weight and cost growth on these shuttle tank structures, composite material tanks of both types are considered.
    Keywords: SPACE VEHICLES
    Type: NASA Space Shuttle Technol. Conf.; p 573-603
    Format: text
    Location Call Number Expected Availability
    BibTip Others were also interested in ...
    NASA TECHNICAL REPORTS
  • 73
    facet.materialart.
    Unknown
    Advanced design concepts for shuttle airframe structure (1972)
    In:  CASI
    Details
    Publication Date: 2005-11-30
    Description: The development of weight-saving advanced design concepts for shuttle airframe structure is presented. Design concepts under investigation employ selective composite reinforcement and/or efficient geometric arrangements. An effort to develop metallic panel designs which exploit the relaxation of smooth external-surface requirements for skin structure is reviewed. Available highlights from research and development studies which investigate the application of composite reinforcement to the design of two types of fuselage panels, a shear web, a large fuselage frame, and a landing-gear-door assembly are presented. Preliminary results from these studies suggest weight savings of 25 percent can be obtained.
    Keywords: SPACE VEHICLES
    Type: NASA Space Shuttle Technol. Conf.; p 537-572
    Format: text
    Location Call Number Expected Availability
    BibTip Others were also interested in ...
    NASA TECHNICAL REPORTS
  • 74
    facet.materialart.
    Unknown
    Flutter technology for space shuttle (1972)
    In:  CASI
    Details
    Publication Date: 2005-11-30
    Description: The development of analytical and experimental techniques needed to predict space shuttle flutter boundaries and insure adequate flutter margins and anticipated problems associated with aeroelastic-model and full-scale testing to validate flutter clearance are considered. Results illustrating the best available tools for subsonic and supersonic flutter prediction are presented. Programs currently underway which will help overcome the difficult problems envisioned for the transonic wind-tunnel and flight flutter test program are also discussed.
    Keywords: SPACE VEHICLES
    Type: NASA Space Shuttle Technol. Conf.; p 1-24
    Format: text
    Location Call Number Expected Availability
    BibTip Others were also interested in ...
    NASA TECHNICAL REPORTS
  • 75
    facet.materialart.
    Unknown
    Gas-powered reentry body erection mechanism (1972)
    In:  CASI
    Details
    Publication Date: 2005-11-30
    Description: The design, analysis, testing, and flight of the supersonic planetary entry decelerator 2 spacecraft are described. The vehicle was launched in a folded condition and deployed to its required configuration following exit from the atmosphere. This concept was selected primarily because it allows utilization of existing launch vehicle systems in the most economical manner possible.
    Keywords: SPACE VEHICLES
    Type: 6th Aerospace Mech. Symp.; p 101-107
    Format: text
    Location Call Number Expected Availability
    BibTip Others were also interested in ...
    NASA TECHNICAL REPORTS
  • 76
    facet.materialart.
    Unknown
    Satellite temperature correlation of predicted, test, and flight data (1972)
    In:  CASI
    Details
    Publication Date: 2005-11-30
    Description: This study compares satellite temperature predictions with thermal vacuum test results and shows the improvement from testing. Orbital data were compared with prediction/test results to determine quantitatively an expected error criteria.
    Keywords: SPACE VEHICLES
    Type: NASA. Goddard Space Flight Center Space Simulation; p 425-443
    Format: text
    Location Call Number Expected Availability
    BibTip Others were also interested in ...
    NASA TECHNICAL REPORTS
  • 77
    facet.materialart.
    Unknown
    Experiments on the dynamic stability of the space shuttle (1972)
    In:  CASI
    Details
    Publication Date: 2005-11-30
    Description: Some dynamic stability experiments on the space shuttle using a half-model oscillatory technique are discussed. Resulting information from the experiments is presented and includes: (1) dynamic pitching characteristics of both the orbiter and the booster alone as well as of the two models mated into a single launch configuration; (2) the static and dynamic interference effects during an abort separation maneuver; and (3) the dynamic plume interference effect.
    Keywords: SPACE VEHICLES
    Type: NASA. Langley Res. Center Space Shuttle Aerothermodyn. Technol. Conf., vol. 3; p 933-968
    Format: text
    Location Call Number Expected Availability
    BibTip Others were also interested in ...
    NASA TECHNICAL REPORTS
  • 78
    facet.materialart.
    Unknown
    Manned spacecraft electrical fire safety (1971)
    In:  CASI
    Details
    Publication Date: 2005-11-30
    Description: The fire hazards created in spacecraft compartments by malfunction of electrical wiring are described. The tests for electrical wire/cable current overload flammability are presented. The application of electrical and material technologies to the reduction of fire hazards in spacecraft are examined.
    Keywords: SPACE VEHICLES
    Type: Conf. on Mater. for Improved Fire Safety; p 173-178
    Format: text
    Location Call Number Expected Availability
    BibTip Others were also interested in ...
    NASA TECHNICAL REPORTS
  • 79
    facet.materialart.
    Unknown
    Aerospace vehicle separation mechanisms selection, design, and use considerations (1971)
    In:  CASI
    Details
    Publication Date: 2005-11-30
    Description: The principal types of separation systems and mechanisms used in spacecraft are described and compared. Important parameters to be considered in tradeoff studies are discussed. Several examples of successful applications and failures and the lessons learned from them are discussed.
    Keywords: SPACE VEHICLES
    Type: NASA. Goddard Space Flight Center 5th Aerospace Mech. Symp.; p 17-23
    Format: text
    Location Call Number Expected Availability
    BibTip Others were also interested in ...
    NASA TECHNICAL REPORTS
  • 80
    facet.materialart.
    Unknown
    Secondary structures and mechanisms - Design trouble area for the space shuttle (1970)
    In:  CASI
    Details
    Publication Date: 2005-11-27
    Description: Secondary structure and mechanism design problems for space shuttles
    Keywords: SPACE VEHICLES
    Type: SPACE TRANSPORTATION SYSTEM TECHNOL. SYMP., VOL. 3 JUL. 1970; P 93-99
    Format: text
    Location Call Number Expected Availability
    BibTip Others were also interested in ...
    NASA TECHNICAL REPORTS
  • 81
    facet.materialart.
    Unknown
    Structural design and analysis of the space shuttle (1970)
    In:  CASI
    Details
    Publication Date: 2005-11-27
    Description: Space shuttle structural design and finite element analysis
    Keywords: SPACE VEHICLES
    Type: NASA. LEWIS RES. CENTER SPACE TRANSPORTATION SYSTEM TECHNOL. SYMP., VOL. 3 JUL. 1970; P 61-71
    Format: text
    Location Call Number Expected Availability
    BibTip Others were also interested in ...
    NASA TECHNICAL REPORTS
  • 82
    facet.materialart.
    Unknown
    Apollo telescope mount operations and data-handling (1970)
    In:  CASI
    Details
    Publication Date: 2005-11-27
    Description: Observation mission and data handling operations for Apollo Telescope Mount
    Keywords: SPACE VEHICLES
    Type: OPT. TELESCOPE TECHNOL. 1970; P 645-656
    Format: text
    Location Call Number Expected Availability
    BibTip Others were also interested in ...
    NASA TECHNICAL REPORTS
  • 83
    facet.materialart.
    Unknown
    Thorad vehicle system performance (1970)
    In:  CASI
    Details
    Publication Date: 2005-11-27
    Description: Thorad launch vehicle system performance
    Keywords: SPACE VEHICLES
    Type: THORAD-AGENA PERFORMANCE FOR THE NIMBUS 3 MISSION JUN. 1970; P 21-40
    Format: text
    Location Call Number Expected Availability
    BibTip Others were also interested in ...
    NASA TECHNICAL REPORTS
  • 84
    facet.materialart.
    Unknown
    Agena vehicle system performance (1970)
    In:  CASI
    Details
    Publication Date: 2005-11-27
    Description: Agena rocket vehicle system description and performance
    Keywords: SPACE VEHICLES
    Type: THORAD-AGENA PERFORMANCE FOR THE NIMBUS 3 MISSION JUN. 1970; P 41-62
    Format: text
    Location Call Number Expected Availability
    BibTip Others were also interested in ...
    NASA TECHNICAL REPORTS
  • 85
    facet.materialart.
    Unknown
    Dynamic testing for shuttle design verification (1972)
    In:  CASI
    Details
    Publication Date: 2005-11-30
    Description: Space shuttle design verification requires dynamic data from full scale structural component and assembly tests. Wind tunnel and other scaled model tests are also required early in the development program to support the analytical models used in design verification. Presented is a design philosophy based on mathematical modeling of the structural system strongly supported by a comprehensive test program; some of the types of required tests are outlined.
    Keywords: SPACE VEHICLES
    Type: NASA Space Shuttle Technol. Conf.; p 231-265
    Format: text
    Location Call Number Expected Availability
    BibTip Others were also interested in ...
    NASA TECHNICAL REPORTS
  • 86
    facet.materialart.
    Unknown
    Neuter docking mechanism study (1972)
    In:  CASI
    Details
    Publication Date: 2005-11-30
    Description: Neuter (or androgynous) docking systems that allow space vehicles with similar or identical docking hardware to dock are discussed. Basic requirements applicable to docking mechanism design, four neuter concepts that were studied, and the concept selected by the NASA Manned Spacecraft Center for detailed investigation are presented.
    Keywords: SPACE VEHICLES
    Type: 6th Aerospace Mech. Symp.; p 43-49
    Format: text
    Location Call Number Expected Availability
    BibTip Others were also interested in ...
    NASA TECHNICAL REPORTS
  • 87
    facet.materialart.
    Unknown
    Aerodynamic studies of delta-wing shuttle orbiters. Part 1: Low speed (1972)
    In:  CASI
    Details
    Publication Date: 2005-11-30
    Description: Numerous wind tunnel tests conducted on the evolving delta-wing orbiters have generated a fairly large aerodynamic data base over the entire entry operation range of these vehicles. A limited assessment is made of some of the aerodynamics of the current HO type orbiters, and several specific problem areas selected from the broad data base are discussed. These include, from a subsonic viewpoint, discussions of trim drag effect; effects of the installation of main rocket engine nozzles, OMS and RCS packages, Reynolds number effects, lateral-directional stability characteristics, and landing characteristics.
    Keywords: SPACE VEHICLES
    Type: Space Shuttle Aerothermodyn. Technol. Conf., vol. 3; p 785-802
    Format: text
    Location Call Number Expected Availability
    BibTip Others were also interested in ...
    NASA TECHNICAL REPORTS
  • 88
    facet.materialart.
    Unknown
    Wing optimization for space shuttle orbiter vehicles (1972)
    In:  CASI
    Details
    Publication Date: 2005-11-30
    Description: The results were presented of a parametric study performed to determine the optimum wing geometry for a proposed space shuttle orbiter. The results of the study establish the minimum weight wing for a series of wing-fuselage combinations subject to constraints on aerodynamic heating, wing trailing edge sweep, and wing over-hang. The study consists of a generalized design evaluation which has the flexibility of arbitrarily varying those wing parameters which influence the vehicle system design and its performance. The study is structured to allow inputs of aerodynamic, weight, aerothermal, structural and material data in a general form so that the influence of these parameters on the design optimization process can be isolated and identified. This procedure displays the sensitivity of the system design of variations in wing geometry. The parameters of interest are varied in a prescribed fashion on a selected fuselage and the effect on the total vehicle weight is determined. The primary variables investigated are: wing loading, aspect ratio, leading edge sweep, thickness ratio, and taper ratio.
    Keywords: SPACE VEHICLES
    Type: NASA. Langley Res. Center Space Shuttle Aerothermodyn. Technol. Conf., vol. 3; p 831-860
    Format: text
    Location Call Number Expected Availability
    BibTip Others were also interested in ...
    NASA TECHNICAL REPORTS
  • 89
    facet.materialart.
    Unknown
    Status of Langley studies of aerodynamics and interference effects of tandem launch vehicles (1972)
    In:  CASI
    Details
    Publication Date: 2005-11-30
    Description: Some of the aerodynamic and interference effects measured from wind-tunnel tests of three fully reusable space shuttle configurations at transonic and low-supersonic speeds are presented, and the status is given of an assessment of the analytical approach to date. The three configurations tested were a low-fineness-ratio booster combined in tandem with a delta-wing orbiter, designated the "low-fineness-ratio configuration,' and a phase B shuttle configuration consisting of the delta-wing orbiter and high-fineness-ratio booster, designated the "stage-arrangement configuration,' arranged in tandem and in parallel. The force measurements obtained at a Mach number of 1.5 for the low-fineness-ratio configuration were representative of the transonic and low-supersonic speed ranges where the interference effects are predominant and were used for comparison with values calculated at the same Mach number. This comparison is the basis for a preliminary assessment of the initial application of the analytical approach.
    Keywords: SPACE VEHICLES
    Type: Space Shuttle Aerothermodyn. Technol. Conf., vol. 3; p 707-736
    Format: text
    Location Call Number Expected Availability
    BibTip Others were also interested in ...
    NASA TECHNICAL REPORTS
  • 90
    facet.materialart.
    Unknown
    Flammability control in the oxygen environment of the Apollo guidance and navigation equipment (1971)
    In:  CASI
    Details
    Publication Date: 2005-11-30
    Description: The Apollo guidance and navigation (G&N) equipment test program, the redesign philosophy, and the actual equipment modifications that were used to limit burn rates in an environment of 100 percent oxygen at pressures of 6.2 and 16 psia are described. The major approach was a serious basic review of the real function of the nonmetallic materials of concern. The result of this review was that the materials could be replaced, eliminated, or covered by nonflammable metallic materials. Although several low-flammability nonmetallic materials were investigated, the direct approach of cover, eliminate, or replace generally proved to be quicker and more effective.
    Keywords: SPACE VEHICLES
    Type: Conf. on Mater. for Improved Fire Safety; p 211-217
    Format: text
    Location Call Number Expected Availability
    BibTip Others were also interested in ...
    NASA TECHNICAL REPORTS
  • 91
    facet.materialart.
    Unknown
    Low-cost ablative heat shields (1970)
    In:  CASI
    Details
    Publication Date: 2005-11-27
    Description: Low cost ablative heat shield program
    Keywords: SPACE VEHICLES
    Type: SPACE TRANSPORTATION SYSTEM TECHNOL. SYMP., VOL. 3 JUL. 1970; P 195-200
    Format: text
    Location Call Number Expected Availability
    BibTip Others were also interested in ...
    NASA TECHNICAL REPORTS
  • 92
    facet.materialart.
    Unknown
    Superalloy heat shield technology for the space shuttle (1970)
    In:  CASI
    Details
    Publication Date: 2005-11-27
    Description: Heat resistant alloy technology for space shuttle reentry shields
    Keywords: SPACE VEHICLES
    Type: NASA. LEWIS RES. CENTER SPACE TRANSPORTATION SYSTEM TECHNOL. SYMP., VOL. 3 JUL. 1970; P 145-158
    Format: text
    Location Call Number Expected Availability
    BibTip Others were also interested in ...
    NASA TECHNICAL REPORTS
  • 93
    facet.materialart.
    Unknown
    Space shuttle structural prototype design, fabrication, and test (1970)
    In:  CASI
    Details
    Publication Date: 2005-11-27
    Description: Space shuttle structural prototype design, fabrication and test program
    Keywords: SPACE VEHICLES
    Type: SPACE TRANSPORTATION SYSTEM TECHNOL. SYMP., VOL. 3 JUL. 1970; P 123-138
    Format: text
    Location Call Number Expected Availability
    BibTip Others were also interested in ...
    NASA TECHNICAL REPORTS
  • 94
    facet.materialart.
    Unknown
    Applications of advanced composite materials to space shuttle structures (1970)
    In:  CASI
    Details
    Publication Date: 2005-11-27
    Description: NASA programs for composite space shuttle structures
    Keywords: SPACE VEHICLES
    Type: SPACE TRANSPORTATION SYSTEM TECHNOL. SYMP., VOL. 3 JUL. 1970; P 73-92
    Format: text
    Location Call Number Expected Availability
    BibTip Others were also interested in ...
    NASA TECHNICAL REPORTS
  • 95
    facet.materialart.
    Unknown
    Space shuttle structural design criteria development (1970)
    In:  CASI
    Details
    Publication Date: 2005-11-27
    Description: NASA structural design criteria development and specific problem areas requiring more study
    Keywords: SPACE VEHICLES
    Type: SPACE TRANSPORTATION SYSTEM TECHNOL. SYMP., VOL. 3 JUL. 1970; P 17-32
    Format: text
    Location Call Number Expected Availability
    BibTip Others were also interested in ...
    NASA TECHNICAL REPORTS
  • 96
    facet.materialart.
    Unknown
    A nutation damper for a spinning satellite (1970)
    In:  CASI
    Details
    Publication Date: 2005-11-27
    Description: Design, testing, and fabrication of nutation damper for small spinning satellites
    Keywords: SPACE VEHICLES
    Type: JPL PROC. OF THE 4TH AEROSPACE MECH. SYMP. 15 JAN. 1970; P 135-142
    Format: text
    Location Call Number Expected Availability
    BibTip Others were also interested in ...
    NASA TECHNICAL REPORTS
  • 97
    facet.materialart.
    Unknown
    A despin assembly for the TACOMSAT communications satellite (1970)
    In:  CASI
    Details
    Publication Date: 2005-11-27
    Description: Design and testing of torque motor driven bearing assembly with integral slip ring unit for experimental tactical communications satellite
    Keywords: SPACE VEHICLES
    Type: JPL PROC. OF THE 4TH AEROSPACE MECH. SYMP. 15 JAN. 1970; P 95-102
    Format: text
    Location Call Number Expected Availability
    BibTip Others were also interested in ...
    NASA TECHNICAL REPORTS
  • 98
    facet.materialart.
    Unknown
    Performance characteristics of the lifting body vehicle (1970)
    In:  CASI
    Details
    Publication Date: 2005-08-18
    Description: Prediction of performance characteristics for lifting body vehicle
    Keywords: SPACE VEHICLES
    Type: FLIGHT TEST RESULTS PERTAINING TO THE SPACE SHUTTLECRAFT OCT. 1970; P 43-58
    Format: text
    Location Call Number Expected Availability
    BibTip Others were also interested in ...
    NASA TECHNICAL REPORTS
  • 99
    facet.materialart.
    Unknown
    Correlation of flight-test loads with wind- tunnel predicted loads on three lifting body vehicles (1970)
    In:  CASI
    Details
    Publication Date: 2005-08-18
    Description: Correlation of flight test loads with wind tunnel predicted loads on three lifting body vehicles
    Keywords: SPACE VEHICLES
    Type: FLIGHT TEST RESULTS PERTAINING TO THE SPACE SHUTTLECRAFT OCT. 1970; P 59-72
    Format: text
    Location Call Number Expected Availability
    BibTip Others were also interested in ...
    NASA TECHNICAL REPORTS
  • 100
    facet.materialart.
    Unknown
    Assessment of lifting body vehicle handling qualities (1970)
    In:  CASI
    Details
    Publication Date: 2005-08-18
    Description: Assessment of lifting body vehicle handling qualities
    Keywords: SPACE VEHICLES
    Type: FLIGHT TEST RESULTS PERTAINING TO THE SPACE SHUTTLECRAFT OCT. 1970; P 29-41
    Format: text
    Location Call Number Expected Availability
    BibTip Others were also interested in ...
    NASA TECHNICAL REPORTS
Close ⊗
This website uses cookies and the analysis tool Matomo. More information can be found here...