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  • 1
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    In:  CASI
    Publication Date: 2004-12-03
    Description: The Moon can be on the pathway to the exploration of other planets in the solar system in three distinct ways: science, systems and technology experience, and as a fuel depot. The most important of these from the point of view of near term potential is to provide systems and technology development that increases capability and reduces the cost and risk of Mars exploration. The development of capability for a lunar program, if planned properly, can significantly influence strategies for sending humans to Mars. In conclusion, the exploration of the Moon should come before the exploration of Mars. This is a statement of developmental and operational logic that is almost self evident. Technological advancement could, however, make a different strategy reasonable. Principally, the development of a propulsion capability that could substantially reduce round trip mission times to Mars (to say 6 to 12 months) could eliminate much of the argument that the Moon is an essential stepping stone. This would reduce the problem to one of similitude with current space station program concepts. However, for any reasonably near term program, such technology does not appear likely to be available. Thus, the answer remains that lunar exploration should come first, and the expectation that it will make Mars exploration much more affordable and safe. The use of lunar propellant in an Earth-Mars transportation system is not practical with current propulsion systems; however, the discovery of caches of water ice at a lunar pole could change considerably the strategy for utilization of lunar resources in planetary exploration.
    Keywords: ASTRONAUTICS (GENERAL)
    Type: ESA, International Lunar Workshop: Towards a World Strategy for the Exploration and Utilisation of Our Natural Satellite; p 123-127
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  • 2
    Publication Date: 2011-08-24
    Description: An analytical solution to the perturbative multiple collision series of a fragmenting HZE ion beam has limited usefulness since the first collision term has several hundred contributions, the second collision term has tens of thousands of contributions, and each successive collision term progresses to unwieldy computational proportions. Our previous work has revealed the multiple collision terms in the straight-ahead approximation to be simple products of a spatially dependent factor times a linear energy-dependent factor of limited domain and unit normalization. The properties of these forms allow the development of the nonperturbative summation of the series to all orders assuming energy-independent nuclear cross sections as matrix products of a scaled Green's function described herein. This nonperturbative Green's function with multiple scattering correction factors compares well with experiments using 670 MeV/u neon-20 ion beams in thick water targets.
    Keywords: Life Sciences (General)
    Type: Radiation research (ISSN 0033-7587); Volume 140; 2; 241-8
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  • 3
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    In:  Other Sources
    Publication Date: 2011-08-24
    Description: Evidence now suggests that satellite cells constitute a class of myogenic cells that differ distinctly from other embryonic myoblasts. Satellite cells arise from somites and first appear as a distinct myoblast type well before birth. Satellite cells from different muscles cannot be functionally distinguished from one another and are able to provide nuclei to all fibers without regard to phenotype. Thus, it is difficult to ascribe any significant function to establishing or stabilizing fiber type, even during regeneration. Within a muscle, satellite cells exhibit marked heterogeneity with respect to their proliferative behavior. The satellite cell population on a fiber can be partitioned into those that function as stem cells and those which are readily available for fusion. Recent studies have shown that the cells are not simply spindle shaped, but are very diverse in their morphology and have multiple branches emanating from the poles of the cells. This finding is consistent with other studies indicating that the cells have the capacity for extensive migration within, and perhaps between, muscles. Complexity of cell shape usually reflects increased cytoplasmic volume and organelles including a well developed Golgi, and is usually associated with growing postnatal muscle or muscles undergoing some form of induced adaptive change or repair. The appearance of activated satellite cells suggests some function of the cells in the adaptive process through elaboration and secretion of a product. Significant advances have been made in determining the potential secretion products that satellite cells make. The manner in which satellite cell proliferative and fusion behavior is controlled has also been studied. There seems to be little doubt that cellcell coupling is not how satellite cells and myofibers communicate. Rather satellite cell regulation is through a number of potential growth factors that arise from a number of sources. Critical to the understanding of this form of control is to determine which of the many growth factors that can alter satellite cell behavior in vitro are at work in vivo. Little work has been done to determine what controls are at work after a regeneration response has been initiated. It seems likely that, after injury, growth factors are liberated through proteolytic activity and initiate an activation process whereby cells enter into a proliferative phase. After myofibers are formed, it also seems likely that satellite cell behavior is regulated through diffusible factors arising from the fibers rather than continuous control by circulating factors.(ABSTRACT TRUNCATED AT 400 WORDS).
    Keywords: Life Sciences (General)
    Type: Reviews of physiology, biochemistry and pharmacology (ISSN 0303-4240); Volume 123; 213-57
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  • 4
    Publication Date: 2011-08-24
    Description: When PCR was used to recover small-subunit (SSU) rRNA genes from a hot spring cyanobacterial mat community, chimeric SSU rRNA sequences which exhibited little or no secondary structural abnormality were recovered. They were revealed as chimeras of SSU rRNA genes of uncultivated species through separate phylogenetic analysis of short sequence domains.
    Keywords: Life Sciences (General)
    Type: Applied and environmental microbiology (ISSN 0099-2240); Volume 60; 2; 746-8
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  • 5
    Publication Date: 2011-08-24
    Description: We performed morphologic studies on skin from seven patients with ALS and seven control subjects. By light microscopy, the wide spaces that separated collagen bundles reacted strongly with colloidal iron and alcian blue in ALS patients. Electron microscopy revealed markedly increased amorphous material that was positive for ruthenium red in the ground substance. These findings were not present in controls. Quantitative amino acid analysis showed that the amount of total amino acids (nmoles per mg dry weight) was significantly decreased (p 〈 0.01) in ALS patients compared with that of controls, and there was a significant negative correlation between skin amino acid content and duration of illness in ALS patients (r = -0.83, p 〈 0.001). These morphologic findings and biochemical data indicate that the amorphous material, which is markedly increased in ALS skin, includes glycosaminoglycans.
    Keywords: Life Sciences (General)
    Type: Neurology (ISSN 0028-3878); Volume 44; 3 Pt 1; 537-40
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  • 6
    Publication Date: 2011-08-24
    Description: The present study assessed the contributions of feeding changes and unloading to the overall measured effects of 2-wk hindlimb (Tail) suspension on the mouse femora. Feeding changes were addressed by considering the effects of matched feeding among suspended and control mice. The effects of hind limb unloading were considered by comparing suspended mice to mice equipped identically (though not suspended) and matched-fed. The feeding and unloading aspects of suspension appear to cause distinctly differing effects on the stereotypic modeling of the femora. Matched-feeding was accompanied by increased resorption surface in comparison to suspended mice, while unloading led to reduced bone formation at the mid-diaphysis of the femora. Reduced mineral content was observed in the bones of suspended mice when compared to the other mice groups, but without increased resorption surface. Thus, the unloading aspects of the antiorthostatic suspension protocol apparently causes reduced formation and mineralization in the femur.
    Keywords: Life Sciences (General)
    Type: The Journal of experimental zoology (ISSN 0022-104X); Volume 269; 3; 277-85
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  • 7
    Publication Date: 2011-08-24
    Description: Dorsal-ventral patterning in the Xenopus egg becomes established midway through the first cell cycle during a 30 degree rotation of the subcortical yolk mass relative to the egg cortex. This 'rotation of symmetrisation' is microtubule dependent, and its direction is thought to be cued by the usually eccentric sperm centrosome. The fact that parthenogenetically activated eggs also undergo a directed rotation, despite the absence of a sperm centrosome, suggests that an endogenous asymmetry in the unfertilised egg supports the directed polymerisation of microtubules in the vegetal cortex, in the way that an eccentric sperm centrosome would in fertilised eggs. Consistent with this idea, we noticed that the maturation spot is usually located an average of more than 15 degrees from the geometric centre of the pigmented animal hemisphere. In parthenogenetically activated eggs, this eccentric maturation spot can be used to predict the direction of rotation. Although in most fertilised eggs the yolk mass rotates toward the sperm entry point (SEP) meridian, occasionally this relationship is perturbed significantly; in such eggs, the maturation spot is never on the same side of the egg as the SEP. In oocytes tilted 90 degrees from upright during maturation in vitro, the maturation spot developed 15 degrees or more from the centre of the pigmented hemisphere, always displaced towards the point on the equator that was up during maturation. This experimentally demonstrated lability is consistent with an off-axis oocyte orientation during oogenesis determining its eccentric maturation spot position, and, in turn, its endogenous rotational bias.
    Keywords: Life Sciences (General)
    Type: Zygote (Cambridge, England) (ISSN 0967-1994); Volume 2; 3; 213-20
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  • 8
    Publication Date: 2011-08-24
    Description: The mitogen phytohemagglutinin (PHA) works well in both human and cynomolgus monkey (Macaca fascicularis) lymphocyte cultures to stimulate T cell proliferation. T cells from rhesus monkeys (Macaca mulatta) are less responsive than human cells, producing few metaphases when thousands are required, e.g. in biological dosimetry studies. We show that staphylococcal enterotoxin A (SEA), one of the most potent mitogens known, at a concentration of 0.5 microgram/ml stimulated peripheral lymphocytes to grow with a mitotic index (MI) averaging 0.13 metaphases/cell in old, irradiated rhesus macaques. This was significantly greater (p 〈 0.001) than that produced by PHA (MI 〈 0.01) in lymphocytes from the same animals. Whole blood was cultured for 96, 120 and 144 h for five irradiated individuals and for two controls. All cells cultured with SEA produced a high MI with a peak response at 120 h whereas the same cultures showed low MI for each PHA stimulated culture.
    Keywords: Life Sciences (General)
    Type: International journal of radiation biology (ISSN 0955-3002); Volume 66; 4; 381-4
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  • 9
    Publication Date: 2011-08-24
    Description: No abstract available
    Keywords: Life Sciences (General)
    Type: Neuron (ISSN 0896-6273); Volume 13; 4; 771-90
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  • 10
    Publication Date: 2011-08-24
    Description: The quality of volume-localized magnetic resonance spectroscopy is affected by eddy currents caused by gradient switching. Eddy currents can be reduced with improved gradient systems; however, it has been suggested that the distortion due to eddy currents can be compensated for during postprocessing with a single-frequency reference signal. The authors propose modifying current techniques for acquiring the single-frequency reference signal by using relaxation weighting to reduce interference from components that cannot be eliminated by digital filtering alone. Additional sequences with T1 or T2 weighting for reference signal acquisition are shown to have the same eddy current characteristics as the original signal without relaxation weighting. The authors also studied a new eddy current correction method that does not require a single-frequency reference signal. This method uses two free induction decays (FIDs) collected from the same volume with two sequences with opposite gradients. Phase errors caused by eddy currents are opposite in these two FIDs and can be canceled completely by combining the FIDs. These methods were tested in a phantom. Eddy current distortions were corrected, allowing quantitative measurement of structures such as the -CH = CH- component, which is otherwise undetectable.
    Keywords: Life Sciences (General)
    Type: Journal of magnetic resonance imaging : JMRI (ISSN 1053-1807); Volume 4; 6; 823-7
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  • 11
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    In:  Other Sources
    Publication Date: 2011-08-24
    Description: Quantitative assessment of the heritable somatic effects of ionizing radiation exposures has relied upon the assumption that radiation-induced lesions were 'fixed' in the DNA prior to the first postirradiation mitosis. Lesion conversion was thought to occur during the initial round of DNA replication or as a consequence of error-prone enzymatic processing of lesions. The standard experimental protocols for the assessment of a variety of radiation-induced endpoints (cell death, specific locus mutations, neoplastic transformation and chromosome aberrations) evaluate these various endpoints at a single snapshot in time. In contrast with the aforementioned approaches, some studies have specifically assessed radiation effects as a function of time following exposure. Evidence has accumulated in support of the hypothesis that radiation exposure induces a persistent destabilization of the genome. This instability has been observed as a delayed expression of lethal mutations, as an enhanced rate of accumulation of non-lethal heritable alterations, and as a progressive intraclonal chromosomal heterogeneity. The genetic controls and biochemical mechanisms underlying radiation-induced genomic instability have not yet been delineated. The aim is to integrate the accumulated evidence that suggests that radiation exposure has a persistent effect on the stability of the mammalian genome.
    Keywords: Life Sciences (General)
    Type: International journal of radiation biology (ISSN 0955-3002); Volume 66; 5; 603-9
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  • 12
    Publication Date: 2011-08-24
    Description: While studies concerning mitogenic factors have been an important area of research for many years, much less is understood about the mechanisms of action of cell surface growth inhibitors. We have purified an 18 kDa cell surface sialoglycopeptide growth inhibitor (CeReS-18) which can reversibly inhibit the proliferation of diverse cell types. The studies discussed in this article show that three mouse keratinocyte cell lines exhibit sixty-fold greater sensitivity than other fibroblasts and epithelial-like cells to CeReS-18-induced growth inhibition. Growth inhibition induced by CeReS-18 treatment is a reversible process, and the three mouse keratinocyte cell lines exhibited either single or multiple cell cycle arrest points, although a predominantly G0/G1 cell cycle arrest point was exhibited in Swiss 3T3 fibroblasts. The sensitivity of the mouse keratinocyte cell lines to CeReS-18-induced growth inhibition was not affected by the degree of tumorigenic progression in the cell lines and was not due to differences in CeReS-18 binding affinity or number of cell surface receptors per cell. However, the sensitivity of both murine fibroblasts and keratinocytes could be altered by changing the extracellular calcium concentration, such that increased extracellular calcium concentrations resulted in decreased sensitivity to CeReS-18-induced proliferation inhibition. Thus the increased sensitivity of the murine keratinocyte cell lines to CeReS-18 could be ascribed to the low calcium concentration used in their propagation. Studies are currently under way investigating the role of calcium in CeReS-18-induced growth arrest. The CeReS-18 may serve as a very useful tool to study negative growth control and the signal transduction events associated with cell cycling.
    Keywords: Life Sciences (General)
    Type: Journal of cellular physiology (ISSN 0021-9541); Volume 161; 3; 553-61
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  • 13
    Publication Date: 2011-08-24
    Description: Space flight represents a form of sensory stimulus rearrangement requiring modification of established terrestrial response patterns through central reinterpretation. Evidence of sensory reinterpretation is manifested as postflight modifications of eye/head coordination, locomotor patterns, postural control strategies, and illusory perceptions of self or surround motion in conjunction with head movements. Under normal preflight conditions, the head is stabilized during locomotion, but immediately postflight reduced head stability, coupled with inappropriate eye/head coordination, results in modifications of gait. Postflight postural control exhibits increased dependence on vision which compensates for inappropriate interpretation of otolith and proprioceptive inputs. Eye movements compensatory for perceived self motion, rather than actual head movements have been observed postflight. Overall, the in-flight adaptive modification of head stabilization strategies, changes in head/eye coordination, illusionary motion, and postural control are maladaptive for a return to the terrestrial environment.
    Keywords: Life Sciences (General)
    Type: Journal of clinical pharmacology (ISSN 0091-2700); Volume 34; 6; 609-17
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  • 14
    Publication Date: 2011-08-24
    Description: No abstract available
    Keywords: Life Sciences (General)
    Type: Journal of medical and veterinary mycology : bi-monthly publication of the International Society for Human and Animal Mycology (ISSN 0268-1218); Volume 32 Suppl 1; 379-406
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  • 15
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    In:  Other Sources
    Publication Date: 2011-08-24
    Description: Bedrest studies of normal subjects provide opportunities to understand physiologic responses to supine posture and inactivity. Furthermore, head-down tilt has been a valuable procedure to investigate adaptation to microgravity and development of countermeasures to maintain the health and well-being of humans during space-flight. Recent bedrest experiments at NASA have ranged in duration from a few hours to 17 weeks. Acute studies of 6 degrees head-down tilt indicate that elevation of capillary blood pressure from 28 to 34 mm Hg and increased capillary perfusion in tissues of the head cause facial and intracranial edema. Intracranial pressure increases from 2 to 17 mm Hg going from upright posture to 6 degrees head-down tilt. Microvessels of the head have a low capacity to constrict and diminish local perfusion. Elevation of blood and tissue fluid pressures/flow in the head may also explain the higher headward bone density associated with long-term head-down tilt. These mechanistic studies of head-down tilt, along with a better understanding of the relative stresses involved with upright posture and lower body negative pressure, have facilitated development of suitable physiologic countermeasures to maintain astronaut health during microgravity. Presently no exercise hardware is available to provide a blood pressure gradient from head to feet in space. However, recent studies in our laboratory suggest that treadmill exercise using a graded lower-body compression suit and 100 mmHg lower body negative pressure provides equivalent or greater physiologic stress than similar upright exercise on Earth. Therefore, exercise within a lower body negative pressure chamber may provide a cost-effective and simple countermeasure to maintain the cardiovascular and neuro-musculoskeletal systems of astronauts during long-duration flight.
    Keywords: Life Sciences (General)
    Type: Acta physiologica Scandinavica. Supplementum (ISSN 0302-2994); Volume 616; 103-14
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  • 16
    Publication Date: 2011-08-24
    Description: There are types of deafness and tinnitus in which ruptures or massive changes in the ionic permeability of the membranes lining the endolymphatic space [e.g., of the reticular lamina (RL)] are believed to allow potassium-rich endolymph to deluge the low [K+] perilymphatic fluid (e.g., in the small spaces of Nuel). This would result in a K+ intoxication of sensory and neural structures. Acute attacks of Meniere's disease have been suggested to be an important example for this event. The present study investigated the effects of transiently elevated [K+] due to the addition of artificial endolymph to the basolateral cell surface of outer hair cells (OHC) in replicating endolymph-induced K+ intoxication of the perilymph in the small spaces of Nuel. The influence of K+ intoxication of the basolateral OHC cell surface on the transduction was then examined. Intoxication resulted in an inhibition of the physiological repolarizing K+ efflux from hair cells. This induced unwanted depolarizations of the hair cells, interfering with mechanoelectrical transduction. A pathological longitudinal OHC shortening was also found, with subsequent compression of the organ of Corti possibly influencing the micromechanics of the mechanically active OHC. Both micromechanical and electrophysiological alterations are proposed to contribute to endolymph leakage induced attacks of deafness and possibly also to tinnitus. Moreover, repeated or long-lasting K+ intoxications of OHC resulted in a chronic and complete loss of OHC motility. This is suggested to be a pathophysiological basis in some patients with chronic hearing loss resulting from Meniere's syndrome.
    Keywords: Life Sciences (General)
    Type: European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery (ISSN 0937-4477); Volume 251; 3; 143-53
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  • 17
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    In:  Other Sources
    Publication Date: 2011-08-24
    Description: No abstract available
    Keywords: Life Sciences (General)
    Type: Advances in space biology and medicine (ISSN 1569-2574); Volume 4; 225-71
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  • 18
    Publication Date: 2011-08-24
    Description: We have developed a computer monitor of nuclear DNA in the form of chromatin fibre. The fibres are modeled as a ideal solenoid consisting of twenty helical turns with six nucleosomes per turn. The chromatin model, in combination with are Monte Carlo theory of radiation damage induces by charged particles, based on general features of tack structure and stopping power theory, has been used to evaluate the influence of DNA structure on initial damage. An interesting has emerged from our calculations. Our calculated results predict the existence of strong spatial correlations in damage sites associated with the symmetries in the solenoidal model. We have calculated spectra of short fragments of double stranded DNA produced by multiple double strand breaks induced by both high and low LET radiation. The spectra exhibit peaks at multiples of approximately 85 base pairs (the nucleosome periodicity), and approximately 1000 base pairs (solenoid periodicity). Preliminary experiments to investigate the fragment distributions from irradiated DNA, made by B. Rydberg at Lawrence Berkeley Laboratory, confirm the existence of short DNA fragments and are in substantial agreement with the predictions of our theory.
    Keywords: Life Sciences (General)
    Type: Basic life sciences (ISSN 0090-5542); Volume 63; 225-35; discussion 235-41
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  • 19
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    Publication Date: 2011-08-24
    Description: Citrate is an inhibitor of the crystallization of stone-forming calcium salts. Hypocitraturia, frequently encountered in patients with nephrolithiasis, is therefore an important risk factor for stone formation. Potassium citrate provides physiological and physicochemical correction and inhibits new stone formation, not only in hypocitraturic calcium nephrolithiasis but also in uric acid nephrolithiasis. Inhibition of stone recurrence has now been validated by a randomized trial. Ongoing research has disclosed additional causes of hypocitraturia (sodium excess, low intestinal alkali absorption, but not primary citrate malabsorption). Moreover, new insights on potassium citrate action have been shown, notably that some of absorbed citrate escapes oxidation and contributes to the citraturic response, that ingestion with a meal does not sacrifice physiological or physicochemical action, that orange juice mimics but does not completely duplicate its actions, that potassium citrate may have a beneficial bone-sparing effect, that it may reduce stone fragments following ESWL, and that danger of aluminum toxicity is not great in subjects with functioning kidneys. Finally, the research on potassium citrate has led to two promising products, calcium citrate as an optimum calcium supplement and potassium-magnesium citrate which may be superior to potassium citrate in the management of stone disease.
    Keywords: Life Sciences (General)
    Type: Mineral and electrolyte metabolism (ISSN 0378-0392); Volume 20; 6; 371-7
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  • 20
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    Publication Date: 2011-08-24
    Description: Major strides in the molecular biology of essential hypertension are currently underway. This has tended to obscure the fact that a number of inherited disorders associated with low blood pressure exist and that these diseases may have milder and underrecognized phenotypes that contribute importantly to blood pressure variation in the general population. This review highlights some of the gene products that, if abnormal, could cause hypotension in some individuals. Diseases due to abnormalities in the catecholamine enzymes are discussed in detail. It is likely that genetic abnormalities with hypotensive phenotypes will be as interesting and diverse as those that give rise to hypertensive disorders.
    Keywords: Life Sciences (General)
    Type: Current opinion in nephrology and hypertension (ISSN 1062-4821); Volume 3; 1; 13-24
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  • 21
    Publication Date: 2011-08-24
    Description: We recorded the horizontal (yaw), vertical (pitch), and torsional (roll) eye movements of two rhesus monkeys with scleral search coils before and after the COSMOS Biosatellite 2229 Flight. The aim was to determine effects of adaptation to microgravity on the vestibulo-ocular reflex (VOR). The animals flew for 11 days. The first postflight tests were 22 h and 55 h after landing, and testing extended for 11 days after reentry. There were four significant effects of spaceflight on functions related to spatial orientation: (1) Compensatory ocular counterrolling (OCR) was reduced by about 70% for static and dynamic head tilts with regard to gravity. The reduction in OCR persisted in the two animals throughout postflight testing. (2) The gain of the torsional component of the angular VOR (roll VOR) was decreased by 15% and 50% in the two animals over the same period. (3) An up-down asymmetry of nystagmus, present in the two monkeys before flight was reduced after exposure to microgravity. (4) The spatial orientation of velocity storage was shifted in the one monkey that could be tested soon after flight. Before flight, the yaw axis eigenvector of optokinetic afternystagmus was close to gravity when the animal was upright or tilted. After flight, the yaw orientation vector was shifted toward the body yaw axis. By 7 days after recovery, it had reverted to a gravitational orientation. We postulate that spaceflight causes changes in the vestibular system which reflect adaptation of spatial orientation from a gravitational to a body frame of reference. These changes are likely to play a role in the postural, locomotor, and gaze instability demonstrated on reentry after spaceflight.
    Keywords: Life Sciences (General)
    Type: Experimental brain research. Experimentelle Hirnforschung. Experimentation cerebrale (ISSN 0014-4819); Volume 102; 1; 45-56
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  • 22
    Publication Date: 2011-08-24
    Description: The high molecular weight aggregate (HMWA) fraction was isolated from the water soluble proteins of aged bovine lenses. Its composition and ability to inhibit heat-induced denaturation and aggregation were compared with the lower molecular weight, oligomeric fraction of alpha isolated from the same lens. Although the major components of both fractions were the alpha-A and alpha-B chains, the HMWA fraction possessed a decreased ability to protect other proteins against heat-induced denaturation and aggregation. Immunoelectron microscopy of both fractions demonstrated that alpha particles from the HMWA fraction contained increased amounts of beta and gamma crystallins, bound to a central region of the supramolecular complex. Together, these results demonstrate that alpha crystallins found in the HMWA fraction possess a decreased ability to protect against heat-induced denaturation and aggregation, and suggest that at least part of this decrease could be due to the increased presence of beta and gamma crystallins complexed to the putative chaperone receptor site of the alpha particles.
    Keywords: Life Sciences (General)
    Type: Current eye research (ISSN 0271-3683); Volume 13; 1; 35-44
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  • 23
    Publication Date: 2011-08-24
    Description: No abstract available
    Keywords: Life Sciences (General)
    Type: Journal of the American Dietetic Association (ISSN 0002-8223); Volume 94; 1; 87-8
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  • 24
    Publication Date: 2011-08-24
    Description: Experiments conducted on STS-50 indicated that space flight significantly inhibited tumor necrosis factor (TNF)-mediated killing of LM929 cells compared to ground controls. In ground-based studies, activation of protein kinase C (PKC) with phorbol 12-myristate 13-acetate (PMA) also inhibited TNF-mediated killing of LM929 cells. Therefore, we used PKC inhibitors to determine if the inhibitory effects of spaceflight on TNF-mediated cytotoxicity involved the activation of PKC. In experiments conducted onboard space shuttle mission STS-54, we saw that in the presence of the protein kinase C inhibitors H7 and H8, TNF-mediated cytotoxicity was restored to levels of those observed in the ground controls. Subsequent experiments done during the STS-57 mission tested the dose response of two protein kinase inhibitors, H7 and HA1004. We again saw that killing was restored in a dose-dependent manner, with inhibitor concentrations known to inhibit PKC being most effective. These data suggest that space flight ameliorates the action of TNF by affecting PKC in target cells.
    Keywords: Life Sciences (General)
    Type: Experimental cell research (ISSN 0014-4827); Volume 211; 1; 171-4
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  • 25
    Publication Date: 2011-08-24
    Description: Focal sarcomere disruptions were previously observed in adductor longus muscles of rats flown approximately two weeks aboard the Cosmos 1887 and 2044 biosatellite flights. These lesions, characterized by breakage and loss of myofilaments and Z-line streaming, resembled damage induced by unaccustomed exercise that includes eccentric contractions in which muscles lengthen as they develop tension. We hypothesized that sarcomere lesions in atrophied muscles of space flow rats were not produced in microgravity by muscle unloading but resulted from muscle reloading upon re-exposure to terrestrial gravity. To test this hypothesis, we examined temporal changes in sarcomere integrity of adductor longus muscles from rats subjected to 12.5 days of hindlimb suspension unloading and subsequent reloading by return to vivarium cages for 0, 6, 12, or 48 hours of normal weightbearing. Our ultrastructural observations suggested that muscle unloading (0 h reloading) induced myofibril misalignment associated with myofiber atrophy. Muscle reloading for 6 hours induced focal sarcomere lesions in which cross striations were abnormally widened. Such lesions were electron lucent due to extensive myofilament loss. Lesions in reloaded muscles showed rapid restructuring. By 12 hours of reloading, lesions were moderately stained foci and by 48 hours darkly stained foci in which the pattern of cross striations was indistinct at the light and electron microscopic levels. These lesions were spanned by Z-line-like electron dense filamentous material. Our findings suggest a new role for Z-line streaming in lesion restructuring: rather than an antecedent to damage, this type of Z-line streaming may be indicative of rapid, early sarcomere repair.
    Keywords: Life Sciences (General)
    Type: The Anatomical record (ISSN 0003-276X); Volume 238; 3; 304-10
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  • 26
    Publication Date: 2011-08-24
    Description: We assessed the reactivity of purified S-100 antiserum in immuno-electron microscopy by counting the number of gold particles per microns 2 over inner ear tissues embedded in different media. Sections containing predominantly Schwann's cell cytoplasm and nucleus, afferent fiber axoplasm and myelin sheath of chick cochleae were reacted with anti-S-100 IgG, an antibody to a calcium binding protein of neuronal tissues, then labeled with anti-IgG-gold conjugate. This investigation was conducted because previously published procedures, unmodified, did not yield acceptable results. Preparation of all specimens was identical. Only the medium (PolyBed 812, Araldite or Spurr epoxies; and LR White, LR Gold or Lowicryl plastics) was changed. The medium was made the changing variable because antigens available in post-embedding immuno-electron microscopy are decreased by heat, either used and/or released during polymerization of the embedding medium. The results indicate that: (a) none of the embedding media above provided optimal signal-to-noise ratio for all parts of the nerve stained in the same section; (b) aggregation of gold particles over cells was highest in embedding media with high background labeling over areas devoid of tissue (noise); (c) aggregation occurred randomly throughout both cellular and acellular regions; and (d) particles aggregated less and were distributed more evenly in tissues from media yielding good ultrastructural integrity.
    Keywords: Life Sciences (General)
    Type: Hearing research (ISSN 0378-5955); Volume 73; 2; 195-202
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  • 27
    Publication Date: 2011-08-24
    Description: A theoretical model is developed to predict the fluid shear stress and streaming potential at the surface of osteocytic processes in the lacunar-canalicular porosity of an osteon when the osteon is subject to mechanical loads that are parallel or perpendicular to its axis. The theory developed in Weinbaum et al. (31) for the flow through a proteoglycan matrix in a canaliculus is employed in a poroelastic model for the osteon. Our formulation is a generalization of that of Petrov et al. (17). Our model predicts that, in order to satisfy the measured frequency dependence of the phase and magnitude of the SGP in macroscopic bone samples, the fiber spacing in the fluid annulus must lie in the narrow range 6-7 nm typical of the spacing of GAG sidechains along a protein monomer. The model predictions for the local SGP profiles in the osteon agree with the experimental observations of Starkebaum et al. (24). The theory predicts that the pore pressure relaxation time, tau d, for a 150-300 microns diameter osteon with the foregoing matrix structure is approximately 0.03-0.13 sec, and that the amplitude of the mean fluid shear stress on the membrane of the osteocytic process at the mean areal radius of the osteon has a maximum at 28 Hz if tau d = 0.06 sec. This maximum, which is independent of the magnitude of the loading, could be important in vivo since the recent experiments of Turner et al. (28) and McLeod et al. (15) have a peak in the strain frequency spectrum between 20 and 30 Hz that also appears to be independent of the type (magnitude) of loading. Numerical predictions for the amplitude of the average fluid shear stress on the osteocytic membrane at the mean areal radius of the osteon show that the fluid shear stress associated with the low amplitude 20-30 Hz spectral strain component is at least as large as the average fluid shear stress associated with the high amplitude 1 Hz stride component, although the latter loading is an order of magnitude larger, and has a magnitude that lies within the middle of the range, 6-30 dynes/cm2, where fluid shear stresses in tissue culture studies with osteoblast monolayers have elicited an intracellular Ca++ response (31). The implications of these results for intracellular electrical communication are discussed.
    Keywords: Life Sciences (General)
    Type: Annals of biomedical engineering (ISSN 0090-6964); Volume 22; 3; 280-92
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  • 28
    Publication Date: 2011-08-24
    Description: Class I and class II major histocompatibility complex (MHC) molecules play significant roles in T cell development and immune function. We show that MHCI- and MHCII-deficient mice have low numbers of macrophage precursors and circulating monocytes, as well as abnormal bone marrow cell colony-stimulating factor type 1 secretion and bone composition. We suggest that MHCI and MHCII molecules play a significant role in macrophage development.
    Keywords: Life Sciences (General)
    Type: Journal of leukocyte biology (ISSN 0741-5400); Volume 55; 5; 658-61
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  • 29
    Publication Date: 2011-08-24
    Description: Recently, it was observed that noncoding regions of DNA sequences possess long-range power-law correlations, whereas coding regions typically display only short-range correlations. We develop an algorithm based on this finding that enables investigators to perform a statistical analysis on long DNA sequences to locate possible coding regions. The algorithm is particularly successful in predicting the location of lengthy coding regions. For example, for the complete genome of yeast chromosome III (315,344 nucleotides), at least 82% of the predictions correspond to putative coding regions; the algorithm correctly identified all coding regions larger than 3000 nucleotides, 92% of coding regions between 2000 and 3000 nucleotides long, and 79% of coding regions between 1000 and 2000 nucleotides. The predictive ability of this new algorithm supports the claim that there is a fundamental difference in the correlation property between coding and noncoding sequences. This algorithm, which is not species-dependent, can be implemented with other techniques for rapidly and accurately locating relatively long coding regions in genomic sequences.
    Keywords: Life Sciences (General)
    Type: Biophysical journal (ISSN 0006-3495); Volume 67; 1; 64-70
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  • 30
    Publication Date: 2011-08-24
    Description: Organ culture of embryonic mouse lung and pancreas rudiments has been used to investigate development and differentiation, and to assess the effects of microgravity on culture differentiation, during orbital spaceflight of the shuttle Endeavour (mission STS-54). Lung rudiments continue to grow and branch during spaceflight, an initial result that should allow future detailed study of lung morphogenesis in microgravity. Cultured embryonic pancreas undergoes characteristic exocrine acinar tissue and endocrine islet tissue differentiation during spaceflight, and in ground controls. The rudiments developing in the microgravity environment of spaceflight appear to grow larger than their ground counterparts, and they may have differentiated more rapidly than controls, as judged by exocrine zymogen granule presence.
    Keywords: Life Sciences (General)
    Type: The Journal of experimental zoology (ISSN 0022-104X); Volume 269; 3; 212-22
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  • 31
    Publication Date: 2011-08-24
    Description: No abstract available
    Keywords: Life Sciences (General)
    Type: American heart journal (ISSN 0002-8703); Volume 128; 1; 202-4
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  • 32
    Publication Date: 2011-08-24
    Description: Myoblast cell cultures have been widely employed in conventional (1g) studies of biological processes because characteristics of intact muscle can be readily observed in these cultured cells. We decided to investigate the effects of spaceflight on muscle by utilizing a well characterized myoblast cell line (L8 rat myoblasts) as cultured in the recently designed Space Tissue Loss Flight Module "A" (STL-A). The STL-A is a "state of the art," compact, fully contained, automated cell culture apparatus which replaces a single mid-deck locker on the Space Shuttle. The L8 cells were successfully flown in the STL-A on the Space Shuttle STS-45 mission. Upon return to earth, reculturing of these spaceflown L8 cells (L8SF) resulted in their unexpected failure to fuse and differentiate into myotubes. This inability of the L8SF cells to fuse was found to be a permanent phenotypic alteration. Scanning electron microscopic examination of L8SF cells growing at 1g on fibronectin-coated polypropylene fibers exhibited a strikingly different morphology as compared to control cells. In addition to their failure to fuse into myotubes, L8SF cells also piled up on top of each other. When assayed in fusion-promoting soft agar, L8SF cells gave rise to substantially more and larger colonies than did either preflight (L8AT) or ground control (L8GC) cells. All data to this point indicate that flying L8 rat myoblasts on the Space Shuttle for a duration of 7-10 d at subconfluent densities results in several permanent phenotypic alterations in these cells.
    Keywords: Life Sciences (General)
    Type: Journal of cellular biochemistry (ISSN 0730-2312); Volume 55; 4; 530-44
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  • 33
    Publication Date: 2011-08-24
    Description: Insulin-like growth factors (IGF) are important regulators of skeletal growth. To determine whether the capacity to produce and respond to these growth factors changes during skeletal development, we measured the protein and mRNA levels for IGF-I, IGF-II, and their receptors (IGF-IR and IGF-IIR, respectively) in the tibia and femur of rats before and up to 28 mo after birth. The mRNA levels remained high during fetal development but fell after birth, reaching a nadir by 3-6 wk. This fall was most pronounced for IGF-II and IGF-IIR mRNA and least pronounced for IGF-I mRNA. However, after 6 wk, both IGF-I and IGF-IR mRNA levels recovered toward the levels observed at birth. In the prenatal bones, the signals for the mRNAs of IGF-II and IGF-IIR were stronger than the signals for the mRNAs of IGF-I and IGF-IR, although the content of IGF-I was three- to fivefold greater than that of IGF-II. IGF-II levels fell postnatally, whereas the IGF-I content rose after birth such that the ratio IGF-I/IGF-II continued to increase with age. We conclude that, during development, rat bone changes its capacity to produce and respond to IGFs with a progressive trend toward the dominance of IGF-I.
    Keywords: Life Sciences (General)
    Type: The American journal of physiology (ISSN 0002-9513); Volume 267; 2 Pt 1; E278-86
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  • 34
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    Publication Date: 2011-08-24
    Description: In eukaryotic cells, microtubules are 24-nm-diameter tubular structures composed of a class of conserved proteins called tubulin. They are involved in numerous cell functions including ciliary motility, nerve cell elongation, pigment migration, centrosome formation, and chromosome movement. Although cytoplasmic tubules and fibers have been observed in bacteria, some with diameters similar to those of eukaryotes, no homologies to eukaryotic microtubules have been established. Certain groups of bacteria including azotobacters, cyanobacteria, enteric bacteria, and spirochetes have been frequently observed to possess microtubule-like structures, and others, including archaebacteria, have been shown to be sensitive to drugs that inhibit the polymerization of microtubules. Although little biochemical or molecular biological information is available, the differences observed among these prokaryotic structures suggest that their composition generally differs among themselves as well as from that of eukaryotes. We review the distribution of cytoplasmic tubules in prokaryotes, even though, in all cases, their functions remain unknown. At least some tend to occur in cells that are large, elongate, and motile, suggesting that they may be involved in cytoskeletal functions, intracellular motility, or transport activities comparable to those performed by eukaryotic microtubules. In Escherichia coli, the FtsZ protein is associated with the formation of a ring in the division zone between the newly forming offspring cells. Like tubulin, FtsZ is a GTPase and shares with tubulin a 7-amino-acid motif, making it a promising candidate in which to seek the origin of tubulins.
    Keywords: Life Sciences (General)
    Type: Microbiological reviews (ISSN 0146-0749); Volume 58; 3; 387-400
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  • 35
    Publication Date: 2011-08-24
    Description: Current therapy for massive venous air embolism (VAE) includes the use of the left lateral recumbent (LLR) position. This recommendation is based on animal studies, conducted 50 yr ago, which looked primarily at survival. Little is known, however, about the concomitant hemodynamic response after VAE in various body positions. The purpose of this study was to investigate the hemodynamic and cardiovascular changes in various body positions after VAE. Twenty-two mechanically ventilated supine mongrel dogs received a venous air infusion of 2.5 mL/kg at a rate of 5 mL/s. One minute after the infusion, 100% oxygen ventilation was commenced and the body position of the dogs was changed to either the LLR (n = 6), the LLR with the head 10 degrees down (LLR-10 degrees; n = 6) or the right lateral recumbent (RLR; n = 5) position. Five dogs were maintained in the supine position (SUP; n = 5). One dog died in every group except in the SUP group, where all the dogs recovered. There were no significant differences among the various body positions in terms of heart rate, mean arterial pressure, pulmonary artery pressure, central venous pressure, left ventricular end-diastolic pressure, or cardiac output. The acute hemodynamic changes occurring during the first 5-15 min after VAE recovered to 80% of control within 60 min. Our data suggest that body repositioning does not influence the cardiovascular response to VAE. Specifically, our data do not support the recommendation of repositioning into the LLR position for the treatment of VAE.
    Keywords: Life Sciences (General)
    Type: Anesthesia and analgesia (ISSN 0003-2999); Volume 79; 4; 734-9
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  • 36
    Publication Date: 2011-08-24
    Description: No abstract available
    Keywords: Life Sciences (General)
    Type: Methods in enzymology (ISSN 0076-6879); Volume 228; 377-90
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  • 37
    Publication Date: 2011-08-24
    Description: This paper reviews a series of studies that indicate that estrogens play an important role in blood volume regulation. The first study illustrates that the plasma volume (PV) of ambulatory women fluctuates during the menstrual cycle, increasing during periods of elevated estrogens. In the second study, it was shown that exogenous and endogenous elevations in blood estrogens attenuate the decrease in PV during bed rest. In the third study, the hypothesis was tested that women, who naturally have a higher blood estrogen content compared with men, will have a smaller loss of PV during bed rest. Ten men and ten women underwent a 13-day, 6 degrees head-down bed rest. Plasma volume and red cell mass (RCM) were measured before and after bed rest using 125I and 51Cr labeling, respectively. Before bed rest, the men and women had similar blood volume (BV) and PV (mL/kg body weight), but the women had a smaller (P 〈 .01) RCM (22.2 +/- 0.9 versus 26.2 +/- 0.8 mL/kg, mean +/- SE). During bed rest, the decrease in RCM (mL/kg) was similar in men and women. However, the decrease in BV was greater in men (8.0 +/- 0.8 mL/kg versus 5.8 +/- 0.8 mL/kg), because of a greater reduction in PV (6.3 +/- 0.6 mL/kg versus 4.1 +/- 0.6 mL/kg). Because the decline in BV has been proposed to contribute to the cardiovascular deconditioning after bed rest, it is possible that women may experience less cardiac and circulatory strain on reambulation.
    Keywords: Life Sciences (General)
    Type: Journal of clinical pharmacology (ISSN 0091-2700); Volume 34; 5; 434-9
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  • 38
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    Publication Date: 2011-08-24
    Description: Life sciences activities being planned for Space Station Freedom (SSF) as of Fall 1992 are discussed. Planning for these activities is ongoing. Therefore, this description should be viewed as indicative of the prevailing ideas at one particular time in the SSF development cycle. The proposed contributions of the Canadian Space Agency (CSN) the European Space Agency (ESA), Japan, and the United States are all discussed in detail. In each case, the life sciences goals, and the way in which each partner proposes to achieve their goals, are reviewed.
    Keywords: Life Sciences (General)
    Type: Journal of clinical pharmacology (ISSN 0091-2700); Volume 34; 6; 703-8
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  • 39
    Publication Date: 2011-08-24
    Description: This paper reviews the cardiovascular responses of six healthy male subjects to 6 hours in a 5 degrees head-down bed rest model of weightlessness, and compares these responses to those obtained when subjects were positioned in head-up tilts of 10 degrees, 20 degrees, and 42 degrees, simulating 1/6, 1/3, and 2/3 G, respectively. Thoracic fluid index, cardiac output, stroke volume, and peak flow were measured using impedance cardiography. Cardiac dimensions and volumes were determined from two-dimensional guided M-mode echocardiograms in the left lateral decubitus position at 0, 2, 4, and 6 hours. Cardiovascular response to a stand test were compared before and after bed rest. The impedance values were related to tilt angle for the first 2 hours of tilt; however, after 3 hours, at all four angles, values began to converge, indicating that cardiovascular homeostatic mechanisms seek a common adapted state, regardless of effective gravity level (tilt angle) up to 2/3 G. Echocardiography revealed that left ventricular end-diastolic and end-systolic volume, stroke volume, ejection fraction, heart rate, and cardiac output had returned to control values by hour 6 for all tilt angles. The lack of a significant immediate change in left ventricular end-diastolic volume, despite decrements in stroke volume (P 〈 .05) and heart rate (not significant), indicates that multiple factors may play a role in the adaptation to simulated hypogravity. The echocardiography data indicated that no angle of tilt, whether head-down or head-up for 4 to 6 hours, mimicked exactly the changes in cardiovascular function recorded after 4 to 6 hours of space flight. Changes in left ventricular end-diastolic volume during space flight and tilt may be similar, but follow a different time course. Nevertheless, head-down tilt at 5 degrees for 6 hours mimics some (stroke volume, systolic and diastolic blood pressure, mean arterial blood pressure, and total resistance), but not all, of the changes occurring in an equivalent time of space flight. The magnitude of the change in the mean heart rate response to standing was greater after six hours of tilt at -5 degrees or 10 degrees. Thus, results from the stand test after 6 hours of bed rest at -5 degrees and 10 degrees, but not at 20 degrees or 42 degrees, are similar to those obtained after space flight.
    Keywords: Life Sciences (General)
    Type: Journal of clinical pharmacology (ISSN 0091-2700); Volume 34; 5; 489-99
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  • 40
    Publication Date: 2011-08-24
    Description: No abstract available
    Keywords: Life Sciences (General)
    Type: Sports medicine (Auckland, N.Z.) (ISSN 0112-1642); Volume 18; 2; 75-80
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  • 41
    Publication Date: 2011-08-24
    Description: Microbalanced stimuli are dynamic displays which do not stimulate motion mechanisms that apply standard (Fourier-energy or autocorrelational) motion analysis directly to the visual signal. In order to extract motion information from microbalanced stimuli, Chubb and Sperling [(1988) Journal of the Optical Society of America, 5, 1986-2006] proposed that the human visual system performs a rectifying transformation on the visual signal prior to standard motion analysis. The current research employs two novel types of microbalanced stimuli: half-wave stimuli preserve motion information following half-wave rectification (with a threshold) but lose motion information following full-wave rectification; full-wave stimuli preserve motion information following full-wave rectification but lose motion information following half-wave rectification. Additionally, Fourier stimuli, ordinary square-wave gratings, were used to stimulate standard motion mechanisms. Psychometric functions (direction discrimination vs stimulus contrast) were obtained for each type of stimulus when presented alone, and when masked by each of the other stimuli (presented as moving masks and also as nonmoving, counterphase-flickering masks). RESULTS: given sufficient contrast, all three types of stimulus convey motion. However, only one-third of the population can perceive the motion of the half-wave stimulus. Observers are able to process the motion information contained in the Fourier stimulus slightly more efficiently than the information in the full-wave stimulus but are much less efficient in processing half-wave motion information. Moving masks are more effective than counterphase masks at hampering direction discrimination, indicating that some of the masking effect is interference between motion mechanisms, and some occurs at earlier stages. When either full-wave and Fourier or half-wave and Fourier gratings are presented simultaneously, there is a wide range of relative contrasts within which the motion directions of both gratings are easily determinable. Conversely, when half-wave and full-wave gratings are combined, the direction of only one of these gratings can be determined with high accuracy. CONCLUSIONS: the results indicate that three motion computations are carried out, any two in parallel: one standard ("first order") and two non-Fourier ("second-order") computations that employ full-wave and half-wave rectification.
    Keywords: Life Sciences (General)
    Type: Vision research (ISSN 0042-6989); Volume 34; 17; 2239-57
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  • 42
    Publication Date: 2011-08-24
    Description: The 3-dimensional crystal structure of glutathione S-transferase (GST) of Schistosoma japonicum (Sj) fused with a conserved neutralizing epitope on gp41 (glycoprotein, 41 kDa) of human immunodeficiency virus type 1 (HIV-1) (Muster T et al., 1993, J Virol 67:6642-6647) was determined at 2.5 A resolution. The structure of the 3-3 isozyme rat GST of the mu gene class (Ji X, Zhang P, Armstrong RN, Gilliland GL, 1992, Biochemistry 31:10169-10184) was used as a molecular replacement model. The structure consists of a 4-stranded beta-sheet and 3 alpha-helices in domain 1 and 5 alpha-helices in domain 2. The space group of the Sj GST crystal is P4(3)2(1)2, with unit cell dimensions of a = b = 94.7 A, and c = 58.1 A. The crystal has 1 GST monomer per asymmetric unit, and 2 monomers that form an active dimer are related by crystallographic 2-fold symmetry. In the binding site, the ordered structure of reduced glutathione is observed. The gp41 peptide (Glu-Leu-Asp-Lys-Trp-Ala) fused to the C-terminus of Sj GST forms a loop stabilized by symmetry-related GSTs. The Sj GST structure is compared with previously determined GST structures of mammalian gene classes mu, alpha, and pi. Conserved amino acid residues among the 4 GSTs that are important for hydrophobic and hydrophilic interactions for dimer association and glutathione binding are discussed.
    Keywords: Life Sciences (General)
    Type: Protein science : a publication of the Protein Society (ISSN 0961-8368); Volume 3; 12; 2233-44
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  • 43
    Publication Date: 2011-08-24
    Description: A repair/misrepair kinetic model for multiple radiation-induced lesions (mutation inactivation) is coupled to a two-mutation model of initiation-promotion in tissue to provide a parametric description of tumour prevalence in the mouse Harderian gland from high-energy and charge radiations. Track-structure effects are considered using an action-cross section model. Dose-response curves are described for gamma rays and relativistic ions, and good agreement with experiment is found. The effects of nuclear fragmentation are also considered for high-energy proton and alpha-particle exposures. The model described provides a parametric description of age-dependent cancer induction for a wide range of radiation fields. Radiosensitivity parameters found in the model for an initiation mutation (sigma 0 = 7.6 x 10(-10) cm2 and D0 = 148.0 Gy) are somewhat different than previously observed for neoplastic transformation of C3H10T1/2 cell cultures (sigma 0 = 0.7 x 10(-10) cm2 and D0 = 117.0 Gy). We consider the two hypotheses that radiation acts solely as an initiator or as both initiator and promoter and make model calculations for fractionation exposures from gamma rays and relativistic Fe ions. For fractionated Fe exposures, an inverse-dose-rate effect is provided by a promotion hypothesis with an increase of 30% or more, dependent on the dose level and fractionation schedule, using a mutation rate for promotion similar to that of single-gene mutations.
    Keywords: Life Sciences (General)
    Type: Physics in medicine and biology (ISSN 0031-9155); Volume 39; 11; 1811-31
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  • 44
    Publication Date: 2011-08-24
    Description: The production of protons in heavy ion collisions through the knockout mechanism (abrasion) is described using the Glauber model. The multiple knockouts from the projectile, including the inelastic collision series with the target, are considered using a closure approximation in treating energy conservation. Calculations for reactions of 12C projectiles with several targets at energies of 1 and 2A GeV arc compared to experiments. For large secondary proton momentum a strong dependence on the target mass is found and attributed to multiple scattering of the projectile knockouts.
    Keywords: Life Sciences (General)
    Type: Journal of physics. G, Nuclear and particle physics : an Institute of Physics journal (ISSN 0954-3899); Volume 20; 11; 1803-15
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  • 45
    Publication Date: 2011-08-24
    Description: The compressible dynamic stall flowfield over a NACA 0012 airfoil transiently pitching from 0 to 60 deg at a constant rate under compressible flow conditions has been studied using real-time interferometry. A quantitative description of the overall flowfield, including the finer details of dynamic stall vortex formation, growth, and the concomitant changes in the airfoil pressure distribution, has been provided by analyzing the interferograms. For Mach numbers above 0.4, small multiple shocks appear near the leading edge and are present through the initial stages of dynamic stall. Dynamic stall was found to occur coincidentally with the bursting of the separation bubble over the airfoil. Compressibility was found to confine the dynamic stall vortical structure closer to the airfoil surface. The measurements show that the peak suction pressure coefficient drops with increasing freestream Mach number, and also it lags the steady flow values at any given angle of attack. As the dynamic stall vortex is shed, an anti-clockwise vortex is induced near the trailing edge, which actively interacts with the post-stall flow.
    Keywords: AERODYNAMICS
    Type: AIAA Journal (ISSN 0001-1452); 32; 3; p. 586-593
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  • 46
    Publication Date: 2011-08-24
    Description: The effect of the porous leading edge of an airfoil on the blade-vortex interaction noise, which dominates the far-field acoustic spectrum of the helicopter, is investigated. The thin-layer Navier-Stokes equations are solved with a high-order upwind-biased scheme and a multizonal grid system. The Baldwin-Lomax turbulence model is modified for considering transpiration on the surface. The amplitudes of the propagating acoustic wave in the near field are calculated directly from the computation. The porosity effect on the surface is modeled in two ways: (1) imposition of prescribed transpiration velocity distribution and (2) calculation of transpiration velocity distribution by Darcy's law. Results show leading-edge transpiration can suppress pressure fluctuations at the leading edge during blade-vortex interaction and consequently reduce the amplitude of propagating noise by 30% at a maximum in the near field.
    Keywords: AERODYNAMICS
    Type: AIAA Journal (ISSN 0001-1452); 32; 3; p. 480-488
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  • 47
    Publication Date: 2011-08-24
    Description: A method has been developed for calculating the viscous flow about airfoils with and without deflected flaps at -90 deg incidence. This method provides for the solution of the unsteady incompressible Navier-Stokes equations by means of an implicit technique. The solution is calculated on a body-fitted computational mesh using a staggered-grid method. The vorticity is defined at the node points, and the velocity components are defined at the mesh-cell sides. The staggered-grid orientation provides for accurate representation of vorticity at the node points and the continuity equation at the mesh-cell centers. The method provides for the noniterative solution of the flowfield and satisfies the continuity equation to machine zero at each time step. The method is evaluated in terms of its stability to predict two-dimensional flow about an airfoil at -90-deg incidence for varying Reynolds number and laminar/turbulent models. The variations of the average loading and surface pressure distribution due to flap deflection, Reynolds number, and laminar or turbulent flow are presented and compared with experimental results. The comparisom indicate that the calculated drag and drag reduction caused by flap deflection and the calculated average surface pressure are in excellent agreement with the measured results at a similar Reynolds number.
    Keywords: AERODYNAMICS
    Type: AIAA Journal (ISSN 0001-1452); 32; 3; p. 449-454
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  • 48
    Publication Date: 2011-08-24
    Description: Rotor noise prediction codes predict the thickness and loading noise produced by a helicopter rotor, given the blade motion, rotor operating conditions, and fluctuating force distribution over the blade surface. However, the criticality of these various inputs, and their respective effects on the predicted acoustic field, have never been fully addressed. This paper examines the importance of these inputs, and the sensitivity of the acoustic predicitions to a variation of each parameter. The effects of collective and cyclic pitch, as well as coning and cyclic flapping, are presented. Blade loading inputs are examined to determine the necessary spatial and temporal resolution, as well as the importance of the chordwise distribution. The acoustic predictions show regions in the acoustic field where significant errors occur when simplified blade motions or blade loadings are used. An assessment of the variation in the predicted acoustic field is balanced by a consideration of Central Processing Unit (CPU) time necessary for the various approximations.
    Keywords: AERODYNAMICS
    Type: American Helicopter Society, Journal (ISSN 0002-8711); 39; 3; p. 43-52
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  • 49
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    Publication Date: 2011-08-24
    Description: The U.S. National Aeronautics and Space Administration (NASA) Balloon Program has been highly successful since recovering from the catastrophic balloon failure problems of the early to mid 1980s. Balloons have continued to perform at unprecedented success rates. The comprehensive research and development (R&D) effort has continued with advances being made across the spectrum of balloon related disciplines. The long duration balloon project will be transitioning from a development effort to an operational capability this year. Recently, emphasis has been placed on the development and implementation of new support systems and facilities. A new permanent launch facility at Fort Sumner, New Mexico has been established. New ground station support equipment is being implemented, and a new heavy load launch vehicle is scheduled to be implemented in 1992. The progress, status and future plans for these and other aspects of the NASA program will be presented.
    Keywords: AERODYNAMICS
    Type: Advances in Space Research (ISSN 0273-1177); 14; 2; p. (2)129-(2)135
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  • 50
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    Publication Date: 2011-08-24
    Description: The catastrophic balloon failure during the first half of the 1980's identified the need for a comprehensive and continuing balloon research and development (R&D) commitment by NASA. Technical understanding was lacking in many of the disciplines and processes associated with scientific ballooning. A comprehensive balloon R&D plan was developed in 1986 and implemented in 1987. The objectives were to develop the understanding of balloon system performance, limitations, and failure mechanisms. The program consisted of five major technical areas: structures, performance and analysis, materials, chemistry and processing, and quality control. Research activitites have been conducted at NASA/Goddard Space Flight Center (GSFC)-Wallops Flight Facility (WFF), other NASA centers and government facilities, universities, and the balloon manufacturers. Several new and increased capabilities and resources have resulted from this activity. The findings, capabilities, and plan of the balloon R&D program are presented.
    Keywords: AERODYNAMICS
    Type: Advances in Space Research (ISSN 0273-1177); 14; 2; p. (2)137-(2)146
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  • 51
    Publication Date: 2011-08-24
    Description: Caps have been used to structurally reinforce scientific research balloons since the late 1950's. The scientific research balloons used by the National Aeronautics and Space Administration (NASA) use internal caps. A NASA cap placement specification does not exist since no empirical information exisits concerning cap placement. To develop a cap placement specification, NASA has completed two in-hangar inflation tests comparing the structural contributions of internal caps and external caps. The tests used small scale test balloons designed to develop the highest possible stresses within the constraints of the hangar and balloon materials. An externally capped test balloon and an internally capped test balloon were designed, built, inflated and simulated to determine the structural contributions and benefits of each. The results of the tests and simulations are presented.
    Keywords: AERODYNAMICS
    Type: Advances in Space Research (ISSN 0273-1177); 14; 2; p. (2)49-(2)52
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  • 52
    Publication Date: 2011-08-24
    Description: The purpose of this Note is to present results from an analytic/experimental study that investigated the potential for passively changing blade twist through the use of extension-twist coupling. A set of composite model rotor blades was manufactured from existing blade molds for a low-twist metal helicopter rotor blade, with a view toward establishing a preliminary proof concept for extension-twist-coupled rotor blades. Data were obtained in hover for both a ballasted and unballasted blade configuration in sea-level atmospheric conditions. Test data were compared with results obtained from a geometrically nonlinear analysis of a detailed finite element model of the rotor blade developed in MSC/NASTRAN.
    Keywords: AERODYNAMICS
    Type: AIAA Journal (ISSN 0001-1452); 32; 7; p. 1549-1551
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  • 53
    Publication Date: 2011-08-24
    Description: The paper considers the compressible Rayleigh equation as a model for the Mach wave emission mechanism associated with high-temperature supersonic jets. Solutions to the compressible Rayleigh equation reveal the existence of several families of supersonically convecting instability waves. These waves directly radiate noise to the jet far field. The predicted noise characteristics are compared to previously acquired experimental data for an axisymmetric Mach 2 fully pressure balanced jet operating over a range of jet total temperatures from ambient to 1370 K. The results of this comparison show that the first-order supersonic instability wave and the Kelvin-Hemlhlotz first-, second-, and third-order modes have directional radiation characteristics that are in agreement with observed data. The assumption of equal initial amplitudes for all of the waves leads to the conclusion that the flapping mode of instability dominates the noise radiatio process of supersonic jets. At a jet temperature of 1370 K, supersonic instability waves are predicted to dominate the noise radiated at high frequency at narrow angles to the jet axis.
    Keywords: AERODYNAMICS
    Type: AIAA Journal (ISSN 0001-1452); 32; 12; p. 2345-2350
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  • 54
    Publication Date: 2011-08-24
    Description: The objective of the present work is to study the mixing characteristics of a linear array of supersonic rectangular jets under conditions of screech synchronization. The screech synchronization at a fully expanded jet Mach number of 1.61 is achieved by a precise adjustment of the internozzle spacing. To our knowledge, such an experiment on the resonant mixing of screech synchronized multiple rectangular jets has not been reported before. The results are compared with the case where the screech was suppressed in the multijet configuration.
    Keywords: AERODYNAMICS
    Type: AIAA Journal (ISSN 0001-1452); 32; 12; p. 2477-2480
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  • 55
    Publication Date: 2011-08-24
    Description: The objective of the present investigation is to assess the effect of the spatial order of accuracy used for the evaluation of the inviscid fluxes on the resolution of higher order quantitites, such as velocity gradients. The viscous terms are computed as second-order accurate with central difference formulas, even though for the explicit part of the algorithm higher order approximations may be used. A viscous/inviscid method is used, and the outer part of the flowfield is computed with the inviscid flow equations. The viscous boundary-layer type flow region close to the body surface is computed with an algebraic eddy viscosity model. Results obtained with the conservative and nonconservative formulations and the viscous/inviscid approach are compared with available experimental data. The effect of grid refinement on the accuracy of the solution is also presented.
    Keywords: AERODYNAMICS
    Type: AIAA Journal (ISSN 0001-1452); 32; 12; p. 2471-2474
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  • 56
    Publication Date: 2011-08-24
    Description: ARC2D is a computational fluid dynamics program developed at the NASA Ames Research Center specifically for airfoil computations. The program uses implicit finite-difference techniques to solve two-dimensional Euler equations and thin layer Navier-Stokes equations. It is based on the Beam and Warming implicit approximate factorization algorithm in generalized coordinates. The methods are either time accurate or accelerated non-time accurate steady state schemes. The evolution of the solution through time is physically realistic; good solution accuracy is dependent on mesh spacing and boundary conditions. The mathematical development of ARC2D begins with the strong conservation law form of the two-dimensional Navier-Stokes equations in Cartesian coordinates, which admits shock capturing. The Navier-Stokes equations can be transformed from Cartesian coordinates to generalized curvilinear coordinates in a manner that permits one computational code to serve a wide variety of physical geometries and grid systems. ARC2D includes an algebraic mixing length model to approximate the effect of turbulence. In cases of high Reynolds number viscous flows, thin layer approximation can be applied. ARC2D allows for a variety of solutions to stability boundaries, such as those encountered in flows with shocks. The user has considerable flexibility in assigning geometry and developing grid patterns, as well as in assigning boundary conditions. However, the ARC2D model is most appropriate for attached and mildly separated boundary layers; no attempt is made to model wake regions and widely separated flows. The techniques have been successfully used for a variety of inviscid and viscous flowfield calculations. The Cray version of ARC2D is written in FORTRAN 77 for use on Cray series computers and requires approximately 5Mb memory. The program is fully vectorized. The tape includes variations for the COS and UNICOS operating systems. Also included is a sample routine for CONVEX computers to emulate Cray system time calls, which should be easy to modify for other machines as well. The standard distribution media for this version is a 9-track 1600 BPI ASCII Card Image format magnetic tape. The Cray version was developed in 1987. The IBM ES/3090 version is an IBM port of the Cray version. It is written in IBM VS FORTRAN and has the capability of executing in both vector and parallel modes on the MVS/XA operating system and in vector mode on the VM/XA operating system. Various options of the IBM VS FORTRAN compiler provide new features for the ES/3090 version, including 64-bit arithmetic and up to 2 GB of virtual addressability. The IBM ES/3090 version is available only as a 9-track, 1600 BPI IBM IEBCOPY format magnetic tape. The IBM ES/3090 version was developed in 1989. The DEC RISC ULTRIX version is a DEC port of the Cray version. It is written in FORTRAN 77 for RISC-based Digital Equipment platforms. The memory requirement is approximately 7Mb of main memory. It is available in UNIX tar format on TK50 tape cartridge. The port to DEC RISC ULTRIX was done in 1990. COS and UNICOS are trademarks and Cray is a registered trademark of Cray Research, Inc. IBM, ES/3090, VS FORTRAN, MVS/XA, and VM/XA are registered trademarks of International Business Machines. DEC and ULTRIX are registered trademarks of Digital Equipment Corporation.
    Keywords: AERODYNAMICS
    Type: COS-10029
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  • 57
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    Publication Date: 2011-08-24
    Description: Panel method computer programs are software tools of moderate cost used for solving a wide range of engineering problems. The panel code PMARC_12 (Panel Method Ames Research Center, version 12) can compute the potential flow field around complex three-dimensional bodies such as complete aircraft models. PMARC_12 is a well-documented, highly structured code with an open architecture that facilitates modifications and the addition of new features. Adjustable arrays are used throughout the code, with dimensioning controlled by a set of parameter statements contained in an include file; thus, the size of the code (i.e. the number of panels that it can handle) can be changed very quickly. This allows the user to tailor PMARC_12 to specific problems and computer hardware constraints. In addition, PMARC_12 can be configured (through one of the parameter statements in the include file) so that the code's iterative matrix solver is run entirely in RAM, rather than reading a large matrix from disk at each iteration. This significantly increases the execution speed of the code, but it requires a large amount of RAM memory. PMARC_12 contains several advanced features, including internal flow modeling, a time-stepping wake model for simulating either steady or unsteady (including oscillatory) motions, a Trefftz plane induced drag computation, off-body and on-body streamline computations, and computation of boundary layer parameters using a two-dimensional integral boundary layer method along surface streamlines. In a panel method, the surface of the body over which the flow field is to be computed is represented by a set of panels. Singularities are distributed on the panels to perturb the flow field around the body surfaces. PMARC_12 uses constant strength source and doublet distributions over each panel, thus making it a low order panel method. Higher order panel methods allow the singularity strength to vary linearly or quadratically across each panel. Experience has shown that low order panel methods can provide nearly the same accuracy as higher order methods over a wide range of cases with significantly reduced computation times; hence, the low order formulation was adopted for PMARC_12. The flow problem is solved by modeling the body as a closed surface dividing space into two regions: the region external to the surface in which an unknown velocity potential exists representing the flow field of interest, and the region internal to the surface in which a known velocity potential (representing a fictitious flow) is prescribed as a boundary condition. Both velocity potentials are required to satisfy Laplace's equation. A surface integral equation for the unknown potential external to the surface can be written by applying Green's Theorem to the external region. Using the internal potential and zero flow through the surface as boundary conditions, the unknown potential external to the surface can be solved for. When the internal flow option, which allows the analysis of closed ducts, wind tunnels, and similar internal flow problems, is selected, the geometry is modeled such that the flow field of interest is inside the geometry and the fictitious flow is outside the geometry. Items such as wings, struts, or aircraft models can be included in the internal flow problem. The time-stepping wake model gives PMARC_12 the ability to model both steady and unsteady flow problems. The wake is convected downstream from the wake-separation line by the local velocity field. With each time step, a new row of wake panels is added to the wake at the wake-separation line. Time stepping can start from time t=0 (no initial wake) or from time t=t0 (an initial wake is specified). A wide range of motions can be prescribed, including constant rates of translation, constant rate of rotation about an arbitrary axis, oscillatory translation, and oscillatory rotation about any of the three coordinate axes. Investigators interested in a visual representation of the phenomenon they are studying with PMARC_12 may want to consider obtaining the program GVS (ARC-13361), the General Visualization System. GVS is a Silicon Graphics IRIS program which was created for the purpose of supporting the scientific visualization needs of PMARC_12. GVS is available separately from COSMIC. PMARC_12 is written in standard FORTRAN 77, with the exception of the NAMELIST extension used for input. This makes the code fairly machine independent. A compiler which supports the NAMELIST extension is required. The amount of free disk space and RAM memory required for PMARC_12 will vary depending on how the code is dimensioned using the parameter statements in the include file. The recommended minimum requirements are 20Mb of free disk space and 4Mb of RAM. PMARC_12 has been successfully implemented on a Macintosh II running System 6.0.7 or 7.0 (using MPW/Language Systems Fortran 3.0), a Sun SLC running SunOS 4.1.1, an HP 720 running HP-UX 8.07, an SGI IRIS running IRIX 4.0 (it will not run under IRIX 3.x.x without modifications), an IBM RS/6000 running AIX, a DECstation 3100 running ULTRIX, and a CRAY-YMP running UNICOS 6.0 or later. Due to its memory requirements, this program does not readily lend itself to implementation on MS-DOS based machines. The standard distribution medium for PMARC_12 is a set of three 3.5 inch 800K Macintosh format diskettes and one 3.5 inch 1.44Mb Macintosh format diskette which contains an electronic copy of the documentation in MS Word 5.0 format for the Macintosh. Alternate distribution media and formats are available upon request, but these will not include the electronic version of the document. No executables are included on the distribution media. This program is an update to PMARC version 11, which was released in 1989. PMARC_12 was released in 1993. It is available only for use by United States citizens.
    Keywords: AERODYNAMICS
    Type: ARC-13362
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  • 58
    Publication Date: 2011-08-24
    Description: This program determines the supersonic flowfield surrounding three-dimensional wing-body configurations of a delta wing. It was designed to provide the numerical computation of three dimensional inviscid, flowfields of either perfect or real gases about supersonic or hypersonic airplanes. The governing equations in conservation law form are solved by a finite difference method using a second order noncentered algorithm between the body and the outermost shock wave, which is treated as a sharp discontinuity. Secondary shocks which form between these boundaries are captured automatically. The flowfield between the body and outermost shock is treated in a shock capturing fashion and therefore allows for the correct formation of secondary internal shocks . The program operates in batch mode, is in CDC update format, has been implemented on the CDC 7600, and requires more than 140K (octal) word locations.
    Keywords: AERODYNAMICS
    Type: ARC-11015
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  • 59
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    Publication Date: 2011-08-24
    Description: This theoretical aerodynamics program, TAD, was developed to predict the aerodynamic characteristics of vehicles with sounding rocket configurations. These slender, axisymmetric finned vehicle configurations have a wide range of aeronautical applications from rockets to high speed armament. Over a given range of Mach numbers, TAD will compute the normal force coefficient derivative, the center-of-pressure, the roll forcing moment coefficient derivative, the roll damping moment coefficient derivative, and the pitch damping moment coefficient derivative of a sounding rocket configured vehicle. The vehicle may consist of a sharp pointed nose of cone or tangent ogive shape, up to nine other body divisions of conical shoulder, conical boattail, or circular cylinder shape, and fins of trapezoid planform shape with constant cross section and either three or four fins per fin set. The characteristics computed by TAD have been shown to be accurate to within ten percent of experimental data in the supersonic region. The TAD program calculates the characteristics of separate portions of the vehicle, calculates the interference between separate portions of the vehicle, and then combines the results to form a total vehicle solution. Also, TAD can be used to calculate the characteristics of the body or fins separately as an aid in the design process. Input to the TAD program consists of simple descriptions of the body and fin geometries and the Mach range of interest. Output includes the aerodynamic characteristics of the total vehicle, or user-selected portions, at specified points over the mach range. The TAD program is written in FORTRAN IV for batch execution and has been implemented on an IBM 360 computer with a central memory requirement of approximately 123K of 8 bit bytes. The TAD program was originally developed in 1967 and last updated in 1972.
    Keywords: AERODYNAMICS
    Type: GSC-12680
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  • 60
    facet.materialart.
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    Publication Date: 2011-08-24
    Description: This program, which is called 'AOFA', determines the complete viscous and inviscid flow around a body of revolution at a given angle of attack and traveling at supersonic speeds. The viscous calculations from this program agree with experimental values for surface and pitot pressures and with surface heating rates. At high speeds, lee-side flows are important because the local heating is difficult to correlate and because the shed vortices can interact with vehicle components such as a canopy or a vertical tail. This program should find application in the design analysis of any high speed vehicle. Lee-side flows are difficult to calculate because thin-boundary-layer theory is not applicable and the concept of matching inviscid and viscous flow is questionable. This program uses the parabolic approximation to the compressible Navier-Stokes equations and solves for the complete inviscid and viscous regions of flow, including the pressure. The parabolic approximation results from the assumption that the stress derivatives in the streamwise direction are small in comparison with derivatives in the normal and circumferential directions. This assumption permits the equation to be solved by an implicit finite difference marching technique which proceeds downstream from the initial data point, provided the inviscid portion of flow is supersonic. The viscous cross-flow separation is also determined as part of the solution. To use this method it is necessary to first determine an initial data point in a region where the inviscid portion of the flow is supersonic. Input to this program consists of two parts. Problem description is conveyed to the program by namelist input. Initial data is acquired by the program as formatted data. Because of the large amount of run time this program can consume the program includes a restart capability. Output is in printed format and magnetic tape for further processing. This program is written in FORTRAN IV and has been implemented on a CDC 7600 with a central memory requirement of approximately 35K (octal) of 60 bit words.
    Keywords: AERODYNAMICS
    Type: ARC-11087
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  • 61
    Publication Date: 2011-08-24
    Description: The Comprehensive Analytical Model of Rotorcraft Aerodynamics, CAMRAD, program is designed to calculate rotor performance, loads, and noise; helicopter vibration and gust response; flight dynamics and handling qualities; and system aeroelastic stability. The analysis is a consistent combination of structural, inertial, and aerodynamic models applicable to a wide range of problems and a wide class of vehicles. The CAMRAD analysis can be applied to articulated, hingeless, gimballed, and teetering rotors with an arbitrary number of blades. The rotor degrees of freedom included are blade/flap bending, rigid pitch and elastic torsion, and optionally gimbal or teeter motion. General two-rotor aircrafts can be modeled. Single main-rotor and tandem helicopter and sideby-side tilting proprotor aircraft configurations can be considered. The case of a rotor or helicopter in a wind tunnel can also be modeled. The aircraft degrees of freedom included are the six rigid body motion, elastic airframe motions, and the rotor/engine speed perturbations. CAMRAD calculates the load and motion of helicopters and airframes in two stages. First the trim solution is obtained; then the flutter, flight dynamics, and/or transient behavior can be calculated. The trim operating conditions considered include level flight, steady climb or descent, and steady turns. The analysis of the rotor includes nonlinear inertial and aerodynamic models, applicable to large blade angles and a high inflow ratio, The rotor aerodynamic model is based on two-dimensional steady airfoil characteristics with corrections for three-dimensional and unsteady flow effects, including a dynamic stall model. In the flutter analysis, the matrices are constructed that describe the linear differential equations of motion, and the equations are analyzed. In the flight dynamics analysis, the stability derivatives are calculated and the matrices are constructed that describe the linear differential equations of motion. These equations are analyzed. In the transient analysis, the rigid body equations of motion are numerically integrated, for a prescribed transient gust or control input. The CAMRAD program product is available by license for a period of ten years to domestic U.S. licensees. The licensed program product includes the CAMRAD source code, command procedures, sample applications, and one set of supporting documentation. Copies of the documentation may be purchased separately at the price indicated below. CAMRAD is written in FORTRAN 77 for the DEC VAX under VMS 4.6 with a recommended core memory of 4.04 megabytes. The DISSPLA package is necessary for graphical output. CAMRAD was developed in 1980.
    Keywords: AERODYNAMICS
    Type: ARC-12337
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  • 62
    Publication Date: 2011-08-24
    Description: ARC2D is a computational fluid dynamics program developed at the NASA Ames Research Center specifically for airfoil computations. The program uses implicit finite-difference techniques to solve two-dimensional Euler equations and thin layer Navier-Stokes equations. It is based on the Beam and Warming implicit approximate factorization algorithm in generalized coordinates. The methods are either time accurate or accelerated non-time accurate steady state schemes. The evolution of the solution through time is physically realistic; good solution accuracy is dependent on mesh spacing and boundary conditions. The mathematical development of ARC2D begins with the strong conservation law form of the two-dimensional Navier-Stokes equations in Cartesian coordinates, which admits shock capturing. The Navier-Stokes equations can be transformed from Cartesian coordinates to generalized curvilinear coordinates in a manner that permits one computational code to serve a wide variety of physical geometries and grid systems. ARC2D includes an algebraic mixing length model to approximate the effect of turbulence. In cases of high Reynolds number viscous flows, thin layer approximation can be applied. ARC2D allows for a variety of solutions to stability boundaries, such as those encountered in flows with shocks. The user has considerable flexibility in assigning geometry and developing grid patterns, as well as in assigning boundary conditions. However, the ARC2D model is most appropriate for attached and mildly separated boundary layers; no attempt is made to model wake regions and widely separated flows. The techniques have been successfully used for a variety of inviscid and viscous flowfield calculations. The Cray version of ARC2D is written in FORTRAN 77 for use on Cray series computers and requires approximately 5Mb memory. The program is fully vectorized. The tape includes variations for the COS and UNICOS operating systems. Also included is a sample routine for CONVEX computers to emulate Cray system time calls, which should be easy to modify for other machines as well. The standard distribution media for this version is a 9-track 1600 BPI ASCII Card Image format magnetic tape. The Cray version was developed in 1987. The IBM ES/3090 version is an IBM port of the Cray version. It is written in IBM VS FORTRAN and has the capability of executing in both vector and parallel modes on the MVS/XA operating system and in vector mode on the VM/XA operating system. Various options of the IBM VS FORTRAN compiler provide new features for the ES/3090 version, including 64-bit arithmetic and up to 2 GB of virtual addressability. The IBM ES/3090 version is available only as a 9-track, 1600 BPI IBM IEBCOPY format magnetic tape. The IBM ES/3090 version was developed in 1989. The DEC RISC ULTRIX version is a DEC port of the Cray version. It is written in FORTRAN 77 for RISC-based Digital Equipment platforms. The memory requirement is approximately 7Mb of main memory. It is available in UNIX tar format on TK50 tape cartridge. The port to DEC RISC ULTRIX was done in 1990. COS and UNICOS are trademarks and Cray is a registered trademark of Cray Research, Inc. IBM, ES/3090, VS FORTRAN, MVS/XA, and VM/XA are registered trademarks of International Business Machines. DEC and ULTRIX are registered trademarks of Digital Equipment Corporation.
    Keywords: AERODYNAMICS
    Type: ARC-12112
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  • 63
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    Publication Date: 2011-08-24
    Description: Panel methods are moderate cost tools for solving a wide range of engineering problems. PMARC (Panel Method Ames Research Center) is a potential flow panel code that numerically predicts flow fields around complex three-dimensional geometries. PMARC's predecessor was a panel code named VSAERO which was developed for NASA by Analytical Methods, Inc. PMARC is a new program with many additional subroutines and a well-documented code suitable for powered-lift aerodynamic predictions. The program's open architecture facilitates modifications or additions of new features. Another improvement is the adjustable size code which allows for an optimum match between the computer hardware available to the user and the size of the problem being solved. PMARC can be resized (the maximum number of panels can be changed) in a matter of minutes. Several other state-of-the-art PMARC features include internal flow modeling for ducts and wind tunnel test sections, simple jet plume modeling essential for the analysis and design of powered-lift aircraft, and a time-stepping wake model which allows the study of both steady and unsteady motions. PMARC is a low-order panel method, which means the singularities are distributed with constant strength over each panel. In many cases low-order methods can provide nearly the same accuracy as higher order methods (where the singularities are allowed to vary linearly or quadratically over each panel). Low-order methods have the advantage of a shorter computation time and do not require exact matching between panels. The flow problem is solved by assuming that the body is at rest in a moving flow field. The body is modeled as a closed surface which divides space into two regions -- one region contains the flow field of interest and the other contains a fictitious flow. External flow problems, such as a wing in a uniform stream, have the external region as the flow field of interest and the internal flow as the fictitious flow. This arrangement is reversed for internal flow problems where the internal region contains the flow field of interest and the external flow field is fictitious. In either case it is assumed that the velocity potentials in both regions satisfy Laplace's equation. PMARC has extensive geometry modeling capabilities for handling complex, three-dimensional surfaces. As with all panel methods, the geometry must be modeled by a set of panels. For convenience, the geometry is usually subdivided into several pieces and modeled with sets of panels called patches. A patch may be folded over on itself so that opposing sides of the patch form a common line. For example, wings are normally modeled with a folded patch to form the trailing edge of the wing. PMARC also has the capability to automatically generate a closing tip patch. In the case of a wing, a tip patch could be generated to close off the wing's third side. PMARC has a simple jet model for simulating a jet plume in a crossflow. The jet plume shape, trajectory, and entrainment velocities are computed using the Adler/Baron jet in crossflow code. This information is then passed back to PMARC. The wake model in PMARC is a time-stepping wake model. The wake is convected downstream from the wake separation line by the local velocity flowfield. With each time step, a new row of wake panels is added to the wake at the wake separation line. PMARC also allows an initial wake to be specified if desired, or, as a third option, no wakes need be modeled. The effective presentation of results for aerodynamics problems requires the generation of report-quality graphics. PMAPP (ARC-12751), the Panel Method Aerodynamic Plotting Program, (Sterling Software), was written for scientists at NASA's Ames Research Center to plot the aerodynamic analysis results (flow data) from PMARC. PMAPP is an interactive, color-capable graphics program for the DEC VAX or MicroVAX running VMS. It was designed to work with a variety of terminal types and hardcopy devices. PMAPP is available separately from COSMIC. PMARC was written in standard FORTRAN77 using adjustable size arrays throughout the code. Redimensioning PMARC will change the amount of disk space and memory the code requires to be able to run; however, due to its memory requirements, this program does not readily lend itself to implementation on MS-DOS based machines. The program was implemented on an Apple Macintosh (using 2.5 MB of memory) and tested on a VAX/VMS computer. The program is available on a 3.5 inch Macintosh format diskette (standard media) or in VAX BACKUP format on TK50 tape cartridge or 9-track magnetic tape. PMARC was developed in 1989.
    Keywords: AERODYNAMICS
    Type: ARC-12642
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  • 64
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    Publication Date: 2011-08-24
    Description: The Transonic Airfoil analysis computer code, TAIR, was developed to employ a fast, fully implicit algorithm to solve the conservative full-potential equation for the steady transonic flow field about an arbitrary airfoil immersed in a subsonic free stream. The full-potential formulation is considered exact under the assumptions of irrotational, isentropic, and inviscid flow. These assumptions are valid for a wide range of practical transonic flows typical of modern aircraft cruise conditions. The primary features of TAIR include: a new fully implicit iteration scheme which is typically many times faster than classical successive line overrelaxation algorithms; a new, reliable artifical density spatial differencing scheme treating the conservative form of the full-potential equation; and a numerical mapping procedure capable of generating curvilinear, body-fitted finite-difference grids about arbitrary airfoil geometries. Three aspects emphasized during the development of the TAIR code were reliability, simplicity, and speed. The reliability of TAIR comes from two sources: the new algorithm employed and the implementation of effective convergence monitoring logic. TAIR achieves ease of use by employing a "default mode" that greatly simplifies code operation, especially by inexperienced users, and many useful options including: several airfoil-geometry input options, flexible user controls over program output, and a multiple solution capability. The speed of the TAIR code is attributed to the new algorithm and the manner in which it has been implemented. Input to the TAIR program consists of airfoil coordinates, aerodynamic and flow-field convergence parameters, and geometric and grid convergence parameters. The airfoil coordinates for many airfoil shapes can be generated in TAIR from just a few input parameters. Most of the other input parameters have default values which allow the user to run an analysis in the default mode by specifing only a few input parameters. Output from TAIR may include aerodynamic coefficients, the airfoil surface solution, convergence histories, and printer plots of Mach number and density contour maps. The TAIR program is written in FORTRAN IV for batch execution and has been implemented on a CDC 7600 computer with a central memory requirement of approximately 155K (octal) of 60 bit words. The TAIR program was developed in 1981.
    Keywords: AERODYNAMICS
    Type: ARC-11436
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  • 65
    Publication Date: 2011-08-24
    Description: The TAWFIVE program calculates transonic flow over a transport-type wing and fuselage. Although more complex Euler and Navier-Stokes methods are available, TAWFIVE combines a multi-grid acceleration technique in the iterative solution of the potential equation with the use of integral-form boundary-layer equations to provide a computationally efficient and sufficiently accurate design tool. TAWFIVE simplifies the solution process by breaking the problem into a loosely coupled set of modified equations. The inviscid method, using standard inviscid equations (nonlinear full potential), is valid in the "outer" region away from the wing, whereas the boundary-layer equations are valid in the thin region near the solid surface of the wing. The two types of equations are coupled by a technique of modifying surface boundary conditions for the inviscid equations. This interaction process starts with a solution of the outer flow field. Pressures are computed at the wing surface and are used to calculate the boundary layer. The boundary-layer and wake properties are then computed using a three-dimensional integral method, and the computed displacement thickness is added to the surface of the "hard" geometry. This new displaced wing surface is then regridded and the inviscid flowfield is recomputed. New values of the inviscid pressures are then used by the boundary-layer method to predict a new displacement thickness distribution. An under-relaxed update of the previously predicted displacement thickness is then made to obtain a new displacement thickness correction that is added to the "hard" geometry. These global iterations are continued until suitable convergence is obtained. Input to TAWFIVE is limited to geometric definition of the configuration, free-stream flow quantities, and iteration control parameters. The geometric input consists of the definition of a series of airfoil sections to define the wing and a series of fuselage cross sections to model the fuselage. High-aspect-ratio wings are modeled more accurately than low-aspect-ratio wings since no special provisions are made to accurately model the wing-fuselage juncture or the wingtip region. The user can specify the solution either in terms of lift or in terms of angle of attack. TAWFIVE can produce tabular output and input files for PLOT3D (COSMIC program number ARC-12779). TAWFIVE is written in FORTRAN 77 for CRAY series computers running UNICOS. The main memory requirement is 2.7Mb for execution. This program is available on a 9-track 1600 BPI UNIX tar format magnetic tape. TAWFIVE was under development from 1979 to 1989 and first released by COSMIC in 1991. CRAY and UNICOS are registered trademarks of Cray Research, Inc.
    Keywords: AERODYNAMICS
    Type: LAR-14722
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  • 66
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    In:  Other Sources
    Publication Date: 2011-08-24
    Description: This computer program is designed to calculate the flow fields in two-dimensional and three-dimensional axisymmetric supersonic inlets. The method of characteristics is used to compute arrays of points in the flow field. At each point the total pressure, local Mach number, local flow angle, and static pressure are calculated. This program can be used to design and analyze supersonic inlets by determining the surface compression rates and throat flow properties. The program employs the method of characteristics for a perfect gas. The basic equation used in the program is the compatibility equation which relates the change in stream angle to the change in entropy and the change in velocity. In order to facilitate the computation, the flow field behind the bow shock wave is broken into regions bounded by shock waves. In each region successive rays are computed from a surface to a shock wave until the shock wave intersects a surface or falls outside the cowl lip. As soon as the intersection occurs a new region is started and the previous region continued only in the area in which it is needed, thus eliminating unnecessary calculations. The maximum number of regions possible in the program is ten, which allows for the simultaneous calculations of up to nine shock waves. Input to this program consists of surface contours, free-stream Mach number, and various calculation control parameters. Output consists of printed and/or plotted results. For plotted results an SC-4020 or similar plotting device is required. This program is written in FORTRAN IV to be executed in the batch mode and has been implemented on a CDC 7600 with a central memory requirement of approximately 27k (octal) of 60 bit words.
    Keywords: AERODYNAMICS
    Type: ARC-11098
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  • 67
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    In:  Other Sources
    Publication Date: 2011-08-24
    Description: This program was developed to predict turbine stage performance taking into account the effects of complex passage geometries. The method uses a quasi-3D inviscid-flow analysis iteratively coupled to calculated losses so that changes in losses result in changes in the flow distribution. In this manner the effects of both the geometry on the flow distribution and the flow distribution on losses are accounted for. The flow may be subsonic or shock-free transonic. The blade row may be fixed or rotating, and the blades may be twisted and leaned. This program has been applied to axial and radial turbines, and is helpful in the analysis of mixed flow machines. This program is a combination of the flow analysis programs MERIDL and TSONIC coupled to the boundary layer program BLAYER. The subsonic flow solution is obtained by a finite difference, stream function analysis. Transonic blade-to-blade solutions are obtained using information from the finite difference, stream function solution with a reduced flow factor. Upstream and downstream flow variables may vary from hub to shroud and provision is made to correct for loss of stagnation pressure. Boundary layer analyses are made to determine profile and end-wall friction losses. Empirical loss models are used to account for incidence, secondary flow, disc windage, and clearance losses. The total losses are then used to calculate stator, rotor, and stage efficiency. This program is written in FORTRAN IV for batch execution and has been implemented on an IBM 370/3033 under TSS with a central memory requirement of approximately 4.5 Megs of 8 bit bytes. This program was developed in 1985.
    Keywords: AERODYNAMICS
    Type: LEW-14218
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  • 68
    Publication Date: 2011-08-24
    Description: Turbomachinery components are often connected by ducts, which are usually annular. The configurations and aerodynamic characteristics of these ducts are crucial to the optimum performance of the turbomachinery blade rows. The ANDUCT computer program was developed to calculate the velocity distribution along an arbitrary line between the inner and outer walls of an annular duct with axisymmetric swirling flow. Although other programs are available for duct analysis, the use of the velocity gradient method makes the ANDUCT program fast and convenient while requiring only modest computer resources. A fast and easy method of analyzing the flow through a duct with axisymmetric flow is the velocity gradient method, also known as the stream filament or streamline curvature method. This method has been used extensively for blade passages but has not been widely used for ducts, except for the radial equilibrium equation. In ANDUCT, a velocity gradient equation derived from the momentum equation is used to determine the velocity variation along an arbitrary straight line between the inner and outer wall of an annular duct. The velocity gradient equation is used with an assumed variation of meridional streamline curvature. Upstream flow conditions may vary between the inner and outer walls, and an assumed total pressure distribution may be specified. ANDUCT works best for well-guided passages and where the curvature of the walls is small as compared to the width of the passage. The ANDUCT program is written in FORTRAN IV for batch execution and has been implemented on an IBM 370 series computer with a central memory requirement of approximately 60K of 8 bit bytes. The ANDUCT program was developed in 1982.
    Keywords: AERODYNAMICS
    Type: LEW-14000
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  • 69
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    In:  Other Sources
    Publication Date: 2011-08-24
    Description: The Panel Code for Planar Cascades was developed as an aid for the designer of turbomachinery blade rows. The effective design of turbomachinery blade rows relies on the use of computer codes to model the flow on blade-to-blade surfaces. Most of the currently used codes model the flow as inviscid, irrotational, and compressible with solutions being obtained by finite difference or finite element numerical techniques. While these codes can yield very accurate solutions, they usually require an experienced user to manipulate input data and control parameters. Also, they often limit a designer in the types of blade geometries, cascade configurations, and flow conditions that can be considered. The Panel Code for Planar Cascades accelerates the design process and gives the designer more freedom in developing blade shapes by offering a simple blade-to-blade flow code. Panel, or integral equation, solution techniques have been used for several years by external aerodynamicists who have developed and refined them into a primary design tool of the aircraft industry. The Panel Code for Planar Cascades adapts these same techniques to provide a versatile, stable, and efficient calculation scheme for internal flow. The code calculates the compressible, inviscid, irrotational flow through a planar cascade of arbitrary blade shapes. Since the panel solution technique is for incompressible flow, a compressibility correction is introduced to account for compressible flow effects. The analysis is limited to flow conditions in the subsonic and shock-free transonic range. Input to the code consists of inlet flow conditions, blade geometry data, and simple control parameters. Output includes flow parameters at selected control points. This program is written in FORTRAN IV for batch execution and has been implemented on an IBM 370 series computer with a central memory requirement of approximately 590K of 8 bit bytes. This program was developed in 1982.
    Keywords: AERODYNAMICS
    Type: LEW-13862
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  • 70
    Publication Date: 2011-08-24
    Description: An exact, full-potential-equation model for the steady, irrotational, homoentropic, and homoenergetic flow of a compressible, inviscid fluid through a two-dimensional planar cascade together with its appropriate boundary conditions has been derived. The CAS2D computer program numerically solves an artificially time-dependent form of the actual full-potential-equation, providing a nonrotating blade-to-blade, steady, potential transonic cascade flow analysis code. Comparisons of results with test data and theoretical solutions indicate very good agreement. In CAS2D, the governing equation is discretized by using type-dependent, rotated finite differencing and the finite area technique. The flow field is discretized by providing a boundary-fitted, nonuniform computational mesh. This mesh is generated by using a sequence of conformal mapping, nonorthogonal coordinate stretching, and local, isoparametric, bilinear mapping functions. The discretized form of the full-potential equation is solved iteratively by using successive line over relaxation. Possible isentropic shocks are captured by the explicit addition of an artificial viscosity in a conservative form. In addition, a four-level, consecutive, mesh refinement feature makes CAS2D a reliable and fast algorithm for the analysis of transonic, two-dimensional cascade flows. The results from CAS2D are not directly applicable to three-dimensional, potential, rotating flows through a cascade of blades because CAS2D does not consider the effects of the Coriolis force that would be present in the three-dimensional case. This program is written in FORTRAN IV for batch execution and has been implemented on an IBM 370 series computer with a central memory requirement of approximately 200K of 8 bit bytes. The CAS2D program was developed in 1980.
    Keywords: AERODYNAMICS
    Type: LEW-13854
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  • 71
    Publication Date: 2011-08-24
    Description: A computer program, QSONIC, has been developed for calculating the full potential, transonic quasi-three-dimensional flow through a rotating turbomachinery blade row. The need for lighter, more efficient turbomachinery components has led to the consideration of machines with fewer stages, each with blades capable of higher speeds and higher loading. As speeds increase, the numerical problems inherent in the transonic regime have to be resolved. These problems include the calculation of imbedded shock discontinuities and the dual nature of the governing equations, which are elliptic in the subcritical flow regions but become hyperbolic for supersonic zones. QSONIC provides the flow analyst with a fast and reliable means of obtaining the transonic potential flow distribution on a blade-to-blade stream surface of a stationary or rotating turbomachine blade row. QSONIC combines several promising transonic analysis techniques. The full potential equation in conservative form is discretized at each point on a body-fitted period mesh. A mass balance is calculated through the finite volume surrounding each point. Each local volume is corrected in the third dimension for any change in stream-tube thickness along the stream tube. The nonlinear equations for all volumes are of mixed type (elliptic or hyperbolic) depending on the local Mach number. The final result is a block-tridiagonal matrix formulation involving potential corrections at each grid point as the unknowns. The residual of each system of equations is solved along each grid line. At points where the Mach number exceeds unity, the density at the forward (sweeping) edge of the volume is replaced by an artificial density. This method calculates the flow field about a cascade of arbitrary two-dimensional airfoils. Three-dimensional flow is approximated in a turbomachinery blade row by correcting for stream-tube convergence and radius change in the through flow direction. Several significant assumptions were made in developing the QSONIC program, including: (1) the flow is inviscid and adiabatic, (2) the flow relative to the blade is steady, (3) the fluid is a perfect gas with constant specific heat, (4) the flow is isentropic and any discontinuities (shocks) are weak enough to be approximated as isentropic jumps, (5) there is no velocity component normal to the stream surface, and (6) the flow relative to a fixed frame in space (absolute velocity) is completely irrotational. These assumptions place some limitations on the application of QSONIC. Sharp leading edges at high incidence and high-Mach-number turbine blade trailing edges with substantial deviation will both cause large velocity peaks on the blade. In addition, the program may have difficulty converging if the passage is nearly choked. Input to QSONIC consists of case control parameters, a geometry description, upstream boundary conditions, and a rotor description. Output includes solution scheme parameters and flow field parameters. A data file is also output which contains data on the solution mesh, surface Mach numbers, surface static pressures, isomachs, and the velocity vector field. This data may be used for further processing or for plotting. The QSONIC is written in FORTRAN IV for batch execution and has been implemented on an IBM 370 series computer with a central memory requirement of approximately 500K of 8 bit bytes. QSONIC was developed in 1982.
    Keywords: AERODYNAMICS
    Type: LEW-13832
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  • 72
    Publication Date: 2011-08-24
    Description: This computer program, WIND, was developed to numerically solve the exact, full-potential equation for three-dimensional, steady, inviscid flow through an isolated wind turbine rotor. The program automatically generates a three-dimensional, boundary-conforming grid and iteratively solves the full-potential equation while fully accounting for both the rotating and Coriolis effects. WIND is capable of numerically analyzing the flow field about a given blade shape of the horizontal-axis type wind turbine. The rotor hub is assumed representable by a doubly infinite circular cylinder. An arbitrary number of blades may be attached to the hub and these blades may have arbitrary spanwise distributions of taper and of the twist, sweep, and dihedral angles. An arbitrary number of different airfoil section shapes may be used along the span as long as the spanwise variation of all the geometeric parameters is reasonably smooth. The numerical techniques employed in WIND involve rotated, type-dependent finite differencing, a finite volume method, artificial viscosity in conservative form, and a successive overrelaxation combined with the sequential grid refinement procedure to accelerate the iterative convergence rate. Consequently, WIND is cabable of accurately analyzing incompressible and compressible flows, including those that are locally transonic and terminated by weak shocks. Along with the three-dimensional results, WIND provides the results of the two-dimensional calculations to aid the user in locating areas of possible improvement in the aerodynamic design of the blade. Output from WIND includes the chordwise distribution of the coefficient of pressure, the Mach number, the density, and the relative velocity components at spanwise stations along the blade. In addition, the results specify local values of the lift coefficient and the tangent and axial aerodynamic force components. These are also given in integrated form expressing the total torque and the total axial force acting on the shaft. WIND can also be used to analyze the flow around isolated aircraft propellers and helicopter rotors in hover as long as the relative oncoming flow is subsonic. The WIND program is written in FORTRAN IV for batch execution and has been implemented on an IBM 370 series computer with a central memory requirement of approximately 253K of 8 bit bytes. WIND was developed in 1980.
    Keywords: AERODYNAMICS
    Type: LEW-13740
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  • 73
    Publication Date: 2011-08-24
    Description: This computer program calculates the flow field in the supersonic portion of a mixed-compression aircraft inlet at non-zero angle of attack. This approach is based on the method of characteristics for steady three-dimensional flow. The results of this program agree with those produced by the two-dimensional method of characteristics when axisymmetric flow fields are calculated. Except in regions of high viscous interaction and boundary layer removal, the results agree well with experimental data obtained for threedimensional flow fields. The flow field in a variety of axisymmetric mixed compression inlets can be calculated using this program. The bow shock wave and the internal shock wave system are calculated using a discrete shock wave fitting procedure. The internal flow field can be calculated either with or without the discrete fitting of the internal shock wave system. The influence of molecular transport can be included in the calculation of the external flow about the forebody and in the calculation of the internal flow when internal shock waves are not discretely fitted. The viscous and thermal diffussion effects are included by treating them as correction terms in the method of characteristics procedure. Dynamic viscosity is represented by Sutherland's law and thermal conductivity is represented as a quadratic function of temperature. The thermodynamic model used is that of a thermally and calorically perfect gas. The program assumes that the cowl lip is contained in a constant plane and that the centerbody contour and cowl contour are smooth and have continuous first partial derivatives. This program cannot calculate subsonic flow, the external flow field if the bow shock wave does not exist entirely around the forebody, or the internal flow field if the bow flow field is injected into the annulus. Input to the program consists of parameters to control execution, to define the geometry, and the vehicle orientation. Output consists of a list of parameters used, solution planes, and a description of the shock waves. This program is written in FORTRAN IV for batch execution and has been implemented on a CDC 6000 series machine with a central memory requirement of 110K (octal) of 60 bit words when it is overlayed. This flow analysis program was developed in 1978.
    Keywords: AERODYNAMICS
    Type: LEW-13279
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  • 74
    Publication Date: 2011-08-24
    Description: This computer program was developed for calculating the subsonic or transonic flow on the hub-shroud mid-channel stream surface of a single blade row of a turbomachine. The design and analysis of blades for compressors and turbines ideally requires methods for analyzing unsteady, three-dimensional, turbulent viscous flow through a turbomachine. Since an exact solution is impossible at present, solutions on two-dimensional surfaces are calculated to obtain a quasi-three dimensional solution. When three-dimensional effects are important, significant information can be obtained from a solution on a cross-sectional surface of the passage normal to the flow. With this program, a solution to the equations of flow on the meridional surface can be carried out. This solution is chosen when the turbomachine under consideration has significant variation in flow properties in the hubshroud direction, especially when input is needed for use in blade-to-blade calculations. The program can also perform flow calculations for annular ducts without blades. This program should prove very useful in the design and analysis of any turbomachine. This program calculates a solution for two-dimensional, adiabatic shockfree flow. The flow must be essentially subsonic, but there may be local areas of supersonic flow. To obtain the solution, this program uses both the finite difference and the quasi-orthogonal (velocity gradient) methods combined in a way that takes maximum advantage of both. The finite-difference method solves a finite-difference equation along the meridional stream surface in a very efficient manner but is limited to subsonic velocities. This approach must be used in cases where the blade aspect ratios are above one, cases where the passage is curved, and cases with low hub-tip-ratio blades. The quasi-orthogonal method solves the velocity gradient equation on the meridional surface and is used if it is necessary to extend the range of solutions into the transonic regime. In general the blade row may be fixed or rotating and the blades may be twisted and leaned. The flow may be axial, radial, or mixed. The upstream and downstream flow conditions can vary from hub to shroud with provisions made for an approximate correction for loss of stagnation pressure. Also, viscous forces are neglected along solution mesh lines running from hub to tip. The capabilities of this program include handling of nonaxial flows without restriction, annular ducts without blades, and specified streamwise loss distributions. This program is written in FORTRAN IV for batch execution and has been implemented on an IBM 360 computer with a central memory requirement of approximately 700K of 8 bit bytes. This core requirement can be reduced depending on the size of the problem and the desired solution accuracy. This program was developed in 1977.
    Keywords: AERODYNAMICS
    Type: LEW-12966
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  • 75
    Publication Date: 2011-08-24
    Description: A computer program has been developed for the design of supersonic rotor blades where losses are accounted for by correcting the ideal blade geometry for boundary layer displacement thickness. The ideal blade passage is designed by the method of characteristics and is based on establishing vortex flow within the passage. Boundary-layer parameters (displacement and momentum thicknesses) are calculated for the ideal passage, and the final blade geometry is obtained by adding the displacement thicknesses to the ideal nozzle coordinates. The boundary-layer parameters are also used to calculate the aftermixing conditions downstream of the rotor blades assuming the flow mixes to a uniform state. The computer program input consists essentially of the rotor inlet and outlet Mach numbers, upper- and lower-surface Mach numbers, inlet flow angle, specific heat ratio, and total flow conditions. The program gas properties are set up for air. Additional gases require changes to be made to the program. The computer output consists of the corrected rotor blade coordinates, the principal boundary-layer parameters, and the aftermixing conditions. This program is written in FORTRAN IV for batch execution and has been implemented on an IBM 7094. This program was developed in 1971.
    Keywords: AERODYNAMICS
    Type: LEW-11744
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  • 76
    Publication Date: 2011-08-24
    Description: This program obtains a transonic flow solution on a blade-to-blade surface between blades of a turbomachine. The flow must be essentially subsonic, but there may be locally supersonic flow. The solution is two-dimensional, isentropic, and shock free. The blades may be fixed or rotating. The flow may be axial, radial, or mixed, and there may be a change in stream-channel thickness in the through-flow direction. A loss in relative stagnation pressure may be accounted for. The program input consists of blade and stream-channel geometry, stagnation flow conditions, inlet and outlet flow angles, and blade-to-blade stream-channel weight flow. The output includes blade surface velocities, velocity magnitude and direction at all interior mesh points in the blade-to-blade passage, and streamline coordinates throughout the passage. The transonic solution is obtained by a combination of a finite-difference, stream-function solution and a velocity-gradient solution. The finite-difference solution at a reduced weight flow provides information needed to obtain a velocity-gradient solution. This program is written in FORTRAN IV for batch execution and has been implemented on the IBM 360 computer with a central memory requirement of approximately 36K of 8 bit bytes. This program was developed in 1969 and last updated in 1979.
    Keywords: AERODYNAMICS
    Type: LEW-10977
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  • 77
    Publication Date: 2011-08-24
    Description: This program is a revision of an existing program for blade-to-blade aerodynamic analysis of turbomachine blades and it is a simpler program while consistent with related programs. The analysis is for two-dimensional, subsonic, compressible (or incompressible), nonviscous flow in a circular or straight infinite cascade of blades, which may be fixed or rotating. The flow may be axial, radial, or mixed, and the stream channel thickness may change in the through-flow direction. The program input consists of blade and stream channel geometry, total flow conditions, inlet and outlet flow angles, and blade-to-blade stream channel weight flow. The output includes blade surface velocities, velocity magnitude and direction at all interior mesh points in the blade-to-blade passage, and streamline coordinates throughout the passage. This program was developed on an IBM 7094/7044 DCS.
    Keywords: AERODYNAMICS
    Type: LEW-10788
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  • 78
    Publication Date: 2011-08-24
    Description: This computer program gives the blade-to-blade solution of the two-dimensional, subsonic, compressible (or incompressible), nonviscous flow problem for a circular or straight infinite cascade of tandem or slotted turbomachine blades. The blades may be fixed or rotating. The flow may be axial, radial , or mixed. The method of solution is based on the stream function using an iterative solution of nonlinear finite-difference equations. These equations are solved using two major levels of iteration. The inner iteration consists of the solution of simultaneous linear equations by successive over-relaxation, using an estimated optimum over-relaxation factor. The outer iteration then changes the coefficients of the simultaneous equations to correct for compressibility. The program input consists of the basic blade geometry, the meridional stream channel coordinates, fluid stagnation conditions, weight flow and flow split through the slot, and inlet and outlet flow angles. The output includes blade surface velocities, velocity magnitude and direction throughout the passage, and the streamline coordinates.
    Keywords: AERODYNAMICS
    Type: LEW-10743
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  • 79
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    Publication Date: 2011-08-24
    Description: This FORTRAN IV computer program which incorporates the method of characteristics was written to assist in the design of supersonic inlets. There were two objectives: (1) to study a greater variety of supersonic inlet configurations and (2) to reduce the time required for trial-and-error procedures to arrive at optimum inlet design. The computer program was written with the intention of being able to construct a variety of inlet configurations by interchanging specific subroutines. In this manner, greater flexibility of choice was attained, and the time required to program a specific inlet configuration was greatly reduced. The second objective was accomplished by a reformulation of the boundary value problem for hyperbolic equations. By this reformulation of the boundary data, the engineering design quantities, throat Mach number and flow angle, were introduced as direct input quantities to the computer program. As a consequence of introducing the engineering parameters as input, the computer program will calculate the surface contours required to satisfy the specific throat conditions. Inviscid flow is assumed and the method used to calculate the inlet contour results in minimum distortion to the flow in the throat. This program was developed on an IBM 7094.
    Keywords: AERODYNAMICS
    Type: LEW-10868
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  • 80
    Publication Date: 2011-08-24
    Description: This program represents a subsonic aerodynamic method for determining the mean camber surface of trimmed noncoplaner planforms with minimum vortex drag. With this program, multiple surfaces can be designed together to yield a trimmed configuration with minimum induced drag at some specified lift coefficient. The method uses a vortex-lattice and overcomes previous difficulties with chord loading specification. A Trefftz plane analysis is used to determine the optimum span loading for minimum drag. The program then solves for the mean camber surface of the wing associated with this loading. Pitching-moment or root-bending-moment constraints can be employed at the design lift coefficient. Sensitivity studies of vortex-lattice arrangements have been made with this program and comparisons with other theories show generally good agreement. The program is very versatile and has been applied to isolated wings, wing-canard configurations, a tandem wing, and a wing-winglet configuration. The design problem solved with this code is essentially an optimization one. A subsonic vortex-lattice is used to determine the span load distribution(s) on bent lifting line(s) in the Trefftz plane. A Lagrange multiplier technique determines the required loading which is used to calculate the mean camber slopes, which are then integrated to yield the local elevation surface. The problem of determining the necessary circulation matrix is simplified by having the chordwise shape of the bound circulation remain unchanged across each span, though the chordwise shape may vary from one planform to another. The circulation matrix is obtained by calculating the spanwise scaling of the chordwise shapes. A chordwise summation of the lift and pitching-moment is utilized in the Trefftz plane solution on the assumption that the trailing wake does not roll up and that the general configuration has specifiable chord loading shapes. VLMD is written in FORTRAN for IBM PC series and compatible computers running MS-DOS. This program requires 360K of RAM for execution. The Ryan McFarland FORTRAN compiler and PLINK86 are required to recompile the source code; however, a sample executable is provided on the diskette. The standard distribution medium for VLMD is a 5.25 inch 360K MS-DOS format diskette. VLMD was originally developed for use on CDC 6000 series computers in 1976. It was originally ported to the IBM PC in 1986, and, after minor modifications, the IBM PC port was released in 1993.
    Keywords: AERODYNAMICS
    Type: LAR-15160
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  • 81
    Publication Date: 2011-08-24
    Description: This code was developed to aid design engineers in the selection and evaluation of aerodynamically efficient wing-canard and wing-horizontal-tail configurations that may employ simple hinged-flap systems. Rapid estimates of the longitudinal aerodynamic characteristics of conceptual airplane lifting surface arrangements are provided. The method is particularly well suited to configurations which, because of high speed flight requirements, must employ thin wings with highly swept leading edges. The code is applicable to wings with either sharp or rounded leading edges. The code provides theoretical pressure distributions over the wing, the canard or horizontal tail, and the deflected flap surfaces as well as estimates of the wing lift, drag, and pitching moments which account for attainable leading edge thrust and leading edge separation vortex forces. The wing planform information is specified by a series of leading edge and trailing edge breakpoints for a right hand wing panel. Up to 21 pairs of coordinates may be used to describe both the leading edge and the trailing edge. The code has been written to accommodate 2000 right hand panel elements, but can easily be modified to accommodate a larger or smaller number of elements depending on the capacity of the target computer platform. The code provides solutions for wing surfaces composed of all possible combinations of leading edge and trailing edge flap settings provided by the original deflection multipliers and by the flap deflection multipliers. Up to 25 pairs of leading edge and trailing edge flap deflection schedules may thus be treated simultaneously. The code also provides for an improved accounting of hinge-line singularities in determination of wing forces and moments. To determine lifting surface perturbation velocity distributions, the code provides for a maximum of 70 iterations. The program is constructed so that successive runs may be made with a given code entry. To make additional runs, it is necessary only to add an identification record and the namelist data that are to be changed from the previous run. This code was originally developed in 1989 in FORTRAN V on a CDC 6000 computer system, and was later ported to an MS-DOS environment. Both versions are available from COSMIC. There are only a few differences between the PC version (LAR-14458) and CDC version (LAR-14178) of AERO2S distributed by COSMIC. The CDC version has one main source code file while the PC version has two files which are easier to edit and compile on a PC. The PC version does not require a FORTRAN compiler which supports NAMELIST because a special INPUT subroutine has been added. The CDC version includes two MODIFY decks which can be used to improve the code and prevent the possibility of some infrequently occurring errors while PC-version users will have to make these code changes manually. The PC version includes an executable which was generated with the Ryan McFarland/FORTRAN compiler and requires 253K RAM and an 80x87 math co-processor. Using this executable, the sample case requires about four hours to execute on an 8MHz AT-class microcomputer with a co-processor. The source code conforms to the FORTRAN 77 standard except that it uses variables longer than six characters. With two minor modifications, the PC version should be portable to any computer with a FORTRAN compiler and sufficient memory. The CDC version of AERO2S is available in CDC NOS Internal format on a 9-track 1600 BPI magnetic tape. The PC version is available on a set of two 5.25 inch 360K MS-DOS format diskettes. IBM AT is a registered trademark of International Business Machines. MS-DOS is a registered trademark of Microsoft Corporation. CDC is a registered trademark of Control Data Corporation. NOS is a trademark of Control Data Corporation.
    Keywords: AERODYNAMICS
    Type: LAR-14178
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  • 82
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    Publication Date: 2011-08-24
    Description: This program provides a wing design algorithm based on modified linear theory which takes into account the effects of attainable leading-edge thrust. A primary objective of the WINGDES2 approach is the generation of a camber surface as mild as possible to produce drag levels comparable to those attainable with full theoretical leading-edge thrust. WINGDES2 provides both an analysis and a design capability and is applicable to both subsonic and supersonic flow. The optimization can be carried out for designated wing portions such as leading and trailing edge areas for the design of mission-adaptive surfaces, or for an entire planform such as a supersonic transport wing. This program replaces an earlier wing design code, LAR-13315, designated WINGDES. WINGDES2 incorporates modifications to improve numerical accuracy and provides additional capabilities. A means of accounting for the presence of interference pressure fields from airplane components other than the wing and a direct process for selection of flap surfaces to approach the performance levels of the optimized wing surfaces are included. An increased storage capacity allows better numerical representation of those configurations that have small chord leading-edge or trailing-edge design areas. WINGDES2 determines an optimum combination of a series of candidate surfaces rather than the more commonly used candidate loadings. The objective of the design is the recovery of unrealized theoretical leading-edge thrust of the input flat surface by shaping of the design surface to create a distributed thrust and thus minimize drag. The input consists of airfoil section thickness data, leading and trailing edge planform geometry, and operational parameters such as Mach number, Reynolds number, and design lift coefficient. Output includes optimized camber surface ordinates, pressure coefficient distributions, and theoretical aerodynamic characteristics. WINGDES2 is written in FORTRAN V for batch execution and has been implemented on a CDC CYBER computer operating under NOS 2.7.1 with a central memory requirement of approximately 344K (octal) of 60 bit words. This program was developed in 1984, and last updated in 1990. CDC and CYBER are trademarks of Control Data Corporation.
    Keywords: AERODYNAMICS
    Type: LAR-13995
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  • 83
    Publication Date: 2011-08-24
    Description: This code was developed to aid design engineers in the selection and evaluation of aerodynamically efficient wing-canard and wing-horizontal-tail configurations that may employ simple hinged-flap systems. Rapid estimates of the longitudinal aerodynamic characteristics of conceptual airplane lifting surface arrangements are provided. The method is particularly well suited to configurations which, because of high speed flight requirements, must employ thin wings with highly swept leading edges. The code is applicable to wings with either sharp or rounded leading edges. The code provides theoretical pressure distributions over the wing, the canard or horizontal tail, and the deflected flap surfaces as well as estimates of the wing lift, drag, and pitching moments which account for attainable leading edge thrust and leading edge separation vortex forces. The wing planform information is specified by a series of leading edge and trailing edge breakpoints for a right hand wing panel. Up to 21 pairs of coordinates may be used to describe both the leading edge and the trailing edge. The code has been written to accommodate 2000 right hand panel elements, but can easily be modified to accommodate a larger or smaller number of elements depending on the capacity of the target computer platform. The code provides solutions for wing surfaces composed of all possible combinations of leading edge and trailing edge flap settings provided by the original deflection multipliers and by the flap deflection multipliers. Up to 25 pairs of leading edge and trailing edge flap deflection schedules may thus be treated simultaneously. The code also provides for an improved accounting of hinge-line singularities in determination of wing forces and moments. To determine lifting surface perturbation velocity distributions, the code provides for a maximum of 70 iterations. The program is constructed so that successive runs may be made with a given code entry. To make additional runs, it is necessary only to add an identification record and the namelist data that are to be changed from the previous run. This code was originally developed in 1989 in FORTRAN V on a CDC 6000 computer system, and was later ported to an MS-DOS environment. Both versions are available from COSMIC. There are only a few differences between the PC version (LAR-14458) and CDC version (LAR-14178) of AERO2S distributed by COSMIC. The CDC version has one main source code file while the PC version has two files which are easier to edit and compile on a PC. The PC version does not require a FORTRAN compiler which supports NAMELIST because a special INPUT subroutine has been added. The CDC version includes two MODIFY decks which can be used to improve the code and prevent the possibility of some infrequently occurring errors while PC-version users will have to make these code changes manually. The PC version includes an executable which was generated with the Ryan McFarland/FORTRAN compiler and requires 253K RAM and an 80x87 math co-processor. Using this executable, the sample case requires about four hours to execute on an 8MHz AT-class microcomputer with a co-processor. The source code conforms to the FORTRAN 77 standard except that it uses variables longer than six characters. With two minor modifications, the PC version should be portable to any computer with a FORTRAN compiler and sufficient memory. The CDC version of AERO2S is available in CDC NOS Internal format on a 9-track 1600 BPI magnetic tape. The PC version is available on a set of two 5.25 inch 360K MS-DOS format diskettes. IBM AT is a registered trademark of International Business Machines. MS-DOS is a registered trademark of Microsoft Corporation. CDC is a registered trademark of Control Data Corporation. NOS is a trademark of Control Data Corporation.
    Keywords: AERODYNAMICS
    Type: LAR-14458
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  • 84
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    Publication Date: 2011-08-24
    Description: Since its early beginnings, NASA has been actively involved in the design and testing of airfoil sections for a wide variety of applications. Recently a set of programs has been developed to smooth and scale arbitrary airfoil coordinates. The smoothing program, AFSMO, utilizes both least-squares polynomial and least-squares cubic-spline techniques to iteratively smooth the second derivatives of the y-axis airfoil coordinates with respect to a transformed x-axis system which unwraps the airfoil and stretches the nose and trailing-edge regions. The corresponding smooth airfoil coordinates are then determined by solving a tridiagonal matrix of simultaneous cubic-spline equations relating the y-axis coordinates and their corresponding second derivatives. The camber and thickness distribution of the smooth airfoil are also computed. The scaling program, AFSCL, may then be used to scale the thickness distribution generated by the smoothing program to a specified maximum thickness. Once the thickness distribution has been scaled, it is combined with the camber distribution to obtain the final scaled airfoil contour. The airfoil smoothing and scaling programs are written in FORTRAN IV for batch execution and have been implemented on a CDC CYBER 170 series computer with a central memory requirement of approximately 70K (octal) of 60 bit words. Both programs generate plotted output via CALCOMP type plotting calls. These programs were developed in 1983.
    Keywords: AERODYNAMICS
    Type: LAR-13132
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  • 85
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    Publication Date: 2011-08-24
    Description: The Supersonic Wing Nonlinear Aerodynamics computer program, LTSTAR, was developed to provide for the estimation of the nonlinear aerodynamic characteristics of a wing at supersonic speeds. This corrected linearized-theory method accounts for nonlinearities in the variation of basic pressure loadings with local surface slopes, predicts the degree of attainment of theoretical leading-edge thrust forces, and provides an estimate of detached leading-edge vortex loadings that result when the theoretical thrust forces are not fully realized. Comparisons of LTSTAR computations with experimental results show significant improvements in detailed wing pressure distributions, particularly for large angles of attack and for regions of the wing where the flow is highly three-dimensional. The program provides generally improved predictions of the wing overall force and moment coefficients. LTSTAR could be useful in design studies aimed at aerodynamic performance optimization and for providing more realistic trade-off information for selection of wing planform geometry and airfoil section parameters. Input to the LTSTAR program includes wing planform data, freestream conditions, wing camber, wing thickness, scaling options, and output options. Output includes pressure coefficients along each chord, section normal and axial force coefficients, and the spanwise distribution of section force coefficients. With the chordwise distributions and section coefficients at each angle of attack, three sets of polars are output. The first set is for linearized theory with and without full leading-edge thrust, the second set includes nonlinear corrections, and the third includes estimates of attainable leading-edge thrust and vortex increments along with the nonlinear corrections. The LTSTAR program is written in FORTRAN IV for batch execution and has been implemented on a CDC 6000 series computer with a central memory requirement of approximately 150K (octal) of 60 bit words. The LTSTAR program was developed in 1980.
    Keywords: AERODYNAMICS
    Type: LAR-12788
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  • 86
    Publication Date: 2011-08-24
    Description: The nozzle afterbody is one of the main drag-producing components of an aircraft propulsion system. Thus, considerable effort has been devoted to developing techniques for predicting the afterbody flow field and drag. The RAXJET computer program was developed to predict the transonic, axisymmetric flow over nozzle afterbodies with supersonic jet exhausts and includes the effects of boundary-layer displacement, separation, jet entrainment, and inviscid jet plume blockage. RAXJET iteratively combines the South-Jameson relaxation procedure, the Reshotko-Tucker boundary-layer solution, the Presz separation model, the Dash-Pergament mixing model, and the Dash-Thorpe inviscid plume model into a single, comprehensive model. The approach taken in the RAXJET program requires considerably less computational time than the Navier-Stokes solutions and generally yields results of comparable accuracy. In RAXJET, the viscous-inviscid interaction model is constructed by dividing the afterbody flow field into six separate computational regions: (1) The inviscid external flow solution is based on the relaxation procedure of South and Jameson for solving the exact nonlinear potential flow equation in nonconservative form. (2) The flow field in the inviscid jet exhaust is solved by explicit spatial marching of the conservative finite-difference form of the inviscid flow equations for a uniform composition gas mixture. (3) The properties in the attached boundary-layer region are solved by a modified version of the Reshotko-Tucker integral method for turbulent flows. (4) The analysis of the separated flow region consists of predicting the separation location and calculating the discriminating streamline shape. (5) The jet wake region is determined by either a simple extrapolation model or by an integral method that accounts for entrainment effects. (6) The displacement-thickness distribution arising from entrainment into the jet mixing layer is calculated by the overlaid mixing model. The inviscid external flow solution and inviscid jet exhaust solution provide the necessary flow conditions to calculate the flow in the viscous regions. The viscous and inviscid flow fields are iteratively solved until a final solution is obtained. Input to the RAXJET program consists of body geometry data, free-stream conditions, main logic control parameters, and condition and control parameters for each of the six computational flow regions. Output from RAXJET includes detailed flow results and aerodynamic coefficients. The RAXJET program is written in FORTRAN IV for batch execution and has been implemented on a CDC CYBER 170 series computer with a central memory requirement of approximately 60K(octal) of 60 bit words. The RAXJET program was developed in 1982.
    Keywords: AERODYNAMICS
    Type: LAR-12957
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  • 87
    Publication Date: 2011-08-24
    Description: The computer program SALLY was developed to compute the incompressible linear stability characteristics and integrate the amplification rates of boundary layer disturbances on swept and tapered wings. For some wing designs, boundary layer disturbance can significantly alter the wing performance characteristics. This is particularly true for swept and tapered laminar flow control wings which incorporate suction to prevent boundary layer separation. SALLY should prove to be a useful tool in the analysis of these wing performance characteristics. The first step in calculating the disturbance amplification rates is to numerically solve the compressible laminar boundary-layer equation with suction for the swept and tapered wing. A two-point finite-difference method is used to solve the governing continuity, momentum, and energy equations. A similarity transformation is used to remove the wall normal velocity as a boundary condition and place it into the governing equations as a parameter. Thus the awkward nonlinear boundary condition is avoided. The resulting compressible boundary layer data is used by SALLY to compute the incompressible linear stability characteristics. The local disturbance growth is obtained from temporal stability theory and converted into a local growth rate for integration. The direction of the local group velocity is taken as the direction of integration. The amplification rate, or logarithmic disturbance amplitude ratio, is obtained by integration of the local disturbance growth over distance. The amplification rate serves as a measure of the growth of linear disturbances within the boundary layer and can serve as a guide in transition prediction. This program is written in FORTRAN IV and ASSEMBLER for batch execution and has been implemented on a CDC CYBER 70 series computer with a central memory requirement of approximately 67K (octal) of 60 bit words. SALLY was developed in 1979.
    Keywords: AERODYNAMICS
    Type: LAR-12556
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  • 88
    Publication Date: 2011-08-24
    Description: The Program for Solving the General-Frequency Unsteady Two-Dimensional Transonic Small-Disturbance Equation, XTRAN2L, is used to calculate time-accurate, finite-difference solutions of the nonlinear, small-disturbance potential equation for two- dimensional transonic flow about airfoils. The code can treat forced harmonic, pulse, or aeroelastic transient type motions. XTRAN2L uses a transonic small-disturbance equation that incorporates a time accurate finite-difference scheme. Airfoil flow tangency boundary conditions are defined to include airfoil contour, chord deformation, nondimensional plunge displacement, pitch, and trailing edge control surface deflection. Forced harmonic motion can be based on: 1) coefficients of harmonics based on information from each quarter period of the last cycle of harmonic motion; or 2) Fourier analyses of the last cycle of motion. Pulse motion (an alternate to forced harmonic motion) in which the airfoil is given a small prescribed pulse in a given mode of motion, and the aerodynamic transients are calculated. An aeroelastic transient capability is available within XTRAN2L, wherein the structural equations of motion are coupled with the aerodynamic solution procedure for simultaneous time-integration. The wake is represented as a slit downstream of the airfoil trailing edge. XTRAN2L includes nonreflecting farfield boundary conditions. XTRAN2L was developed on a CDC CYBER mainframe running under NOS 2.4. It is written in FORTRAN 5 and uses overlays to minimize storage requirements. The program requires 120K of memory in overlayed form. XTRAN2L was developed in 1987.
    Keywords: AERODYNAMICS
    Type: LAR-13899
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  • 89
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    Publication Date: 2011-08-24
    Description: The NASCRIN program was developed for analyzing two-dimensional flow fields in supersonic combustion ramjet (scramjet) inlets. NASCRIN solves the two-dimensional Euler or Navier-Stokes equations in conservative form by an unsplit, explicit, two-step finite-difference method. A more recent explicit-implicit, two-step scheme has also been incorporated in the code for viscous flow analysis. An algebraic, two-layer eddy-viscosity model is used for the turbulent flow calculations. NASCRIN can analyze both inviscid and viscous flows with no struts, one strut, or multiple struts embedded in the flow field. NASCRIN can be used in a quasi-three-dimensional sense for some scramjet inlets under certain simplifying assumptions. Although developed for supersonic internal flow, NASCRIN may be adapted to a variety of other flow problems. In particular, it should be readily adaptable to subsonic inflow with supersonic outflow, supersonic inflow with subsonic outflow, or fully subsonic flow. The NASCRIN program is available for batch execution on the CDC CYBER 203. The vectorized FORTRAN version was developed in 1983. NASCRIN has a central memory requirement of approximately 300K words for a grid size of about 3,000 points.
    Keywords: AERODYNAMICS
    Type: LAR-13297
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  • 90
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    Publication Date: 2011-08-24
    Description: The problem of axisymmetric transonic flow is of interest not only because of the practical application to missile and launch vehicle aerodynamics, but also because of its relation to fully three-dimensional flow in terms of the area rule. The RAXBOD computer program was developed for the analysis of steady, inviscid, irrotational, transonic flow over axisymmetric bodies in free air. RAXBOD uses a finite-difference relaxation method to numerically solve the exact formulation of the disturbance velocity potential with exact surface boundary conditions. Agreement with available experimental results has been good in cases where viscous effects and wind-tunnel wall interference are not important. The governing second-order partial differential equation describing the flow potential is replaced by a system of finite difference equations, including Jameson's "rotated" difference scheme at supersonic points. A stretching is applied to both the normal and tangential coordinates such that the infinite physical space is mapped onto a finite computational space. The boundary condition at infinity can be applied directly and there is no need for an asymptotic far-field solution. The system of finite difference equations is solved by a column relaxation method. In order to obtain both rapid convergence and any desired resolution, the relaxation is performed iteratively on successively refined grids. Input to RAXBOD consists of a description of the body geometry, the free stream conditions, and the desired resolution control parameters. Output from RAXBOD includes computed geometric parameters in the normal and tangential directions, iteration history information, drag coefficients, flow field data in the computational plane, and coordinates of the sonic line. This program is written in FORTRAN IV for batch execution and has been implemented on a CDC 6600 computer with an overlayed central memory requirement of approximately 40K (octal) of 60 bit words. Optional plotted output can be generated for the Calcomp plotting system. The RAXBOD program was developed in 1976.
    Keywords: AERODYNAMICS
    Type: LAR-12499
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  • 91
    Publication Date: 2011-08-24
    Description: Two separate and distinct theories are incorporated in this computer program to estimate the lift-induced pressures existent on a wing-body combination. These are (1) the second-order shock-expansion theory, which is used to obtain the lifting pressures on the body alone at small angles of attack, and (2) the linear-theory integral equations, which is used to evaluate the lifting pressures induced by the wing. These equations relate the local surface slope at a point on the lifting surface to the pressure differential at the point and the influence of the pressures upstream of the point. The numerical solution of these equations is effected by treating the wing-planform as a composite of elemental rectangles and applying summation techniques to satisfy the necessary integral relations. Most of the input required by this program is involved with the description of the missile planform geometry. The output consists of the computed value of the lifting pressure slope (the differential pressure coefficient per degree angle of attack) for each of the elements in the planform array. A force and moment summary is presented for the configuration under consideration.
    Keywords: AERODYNAMICS
    Type: LAR-10932
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  • 92
    Publication Date: 2011-08-24
    Description: A modified strip analysis has been developed for rapidly predicting flutter of finite-span, swept or unswept wings at subsonic to hypersonic speeds. The method employs distributions of aerodynamic parameters which may be evaluated from any suitable linear or nonlinear steady-flow theory or from measured steady-flow load distributions for the underformed wing. The method has been shown to give good flutter results for a broad range of wings at Mach number from 0 to as high as 15.3. The principles of the modified strip analysis may be summarized as follows: Variable section lift-curve slope and aerodynamic center are substituted respectively, for the two-dimensional incompressible-flow values of 2 pi and quarter chord which were employed by Barmby, Cunningham, and Garrick. Spanwise distributions of these steady-flow section aerodynamic parameters, which are pertinent to the desired planform and Mach number, are used. Appropriate values of Mach number-dependent circulation functions are obtained from two-dimensional unsteady compressible-flow theory. Use of the modified strip analysis avoids the necessity of reevaluating a number of loading parameters for each value of reduced frequency, since only the modified circulation functions, and of course the reduced frequency itself, vary with frequency. It is therefore practical to include in the digital computing program a very brief logical subroutine, which automatically selects reduced-frequency values that converge on a flutter solution. The problem of guessing suitable reduced-frequency values is thus eliminated, so that a large number of flutter points can be completely determined in a single brief run on the computing machine. If necessary, it is also practical to perform the calculations manually. Flutter characteristics have been calculated by the modified strip analysis and compared with results of other calculations and with experiments for Mach numbers up to 15.3 and for wings with sweep angles from 0 degrees to 52.5 degrees, aspect ratios from 2.0 to 7.4, taper ratios from 0.2 to 1.0, and center-of-gravity positions between 34% chord and 59% chord. These ranges probably cover the great majority of wings that are of practical interest with the exception of very low-aspect-ratio surfaces such as delta wings and missile fins. This program has been implemented on the IBM 7094.
    Keywords: AERODYNAMICS
    Type: LAR-10199
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  • 93
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    Publication Date: 2011-08-24
    Description: The SUBAERF2 program was developed to provide for the aerodynamic analysis and design of low speed wing flap systems. SUBAERF2 is based on a linearized theory lifting surface solution. It is particularly well suited to configurations which, because of high speed flight requirements, must employ thin wings with highly swept leading edges. The program is applicable to wings with either sharp or rounded leading edges. This program is a new and improved version of LAR-13116 and LAR-12987, which it replaces. The low speed aerodynamic analysis method used in SUBAERF2 provides estimates of wing performance which include the effects of attainable leading-edge thrust and vortex lift. This basic aerodynamic analysis method has been improved to provide for the convenient, efficient and accurate treatment of simple leading-edge and trailing-edge flap systems. The user inputs flap geometry directly. Solutions can be found for various combinations of leading and trailing edge flap deflections. The program provides for the simultaneous analysis of up to 25 pairs of leading-edge and trailing-edge flap deflection schedules. A revised attainable thrust algorithm improves accuracy at the low Mach numbers sometimes encountered in wind tunnel testing. Also added is a means of estimating the distribution of leading edge separation vortex forces. The revised program has been particularly useful in the subsonic analysis of vehicles designed for supersonic cruise. The SUBAERF2 program is written in FORTRAN V for batch execution and has been implemented on a CDC 175 computer operating under NOS 2.4 with a central memory requirement of approximately 115K (octal) of 60 bit words. This program was originally developed in 1983 and later revised in 1988.
    Keywords: AERODYNAMICS
    Type: LAR-13994
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  • 94
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    Publication Date: 2011-08-24
    Description: WAVDRAG calculates the supersonic zero-lift wave drag of complex aircraft configurations. The numerical model of an aircraft is used throughout the design process from concept to manufacturing. WAVDRAG incorporates extended geometric input capabilities to permit use of a more accurate mathematical model. With WAVDRAG, the engineer can define aircraft components as fusiform or nonfusiform in terms of non-intersecting contours in any direction or more traditional parallel contours. In addition, laterally asymmetric configurations can be simulated. The calculations in WAVDRAG are based on Whitcomb's area-rule computation of equivalent-bodies, with modifications for supersonic speed. Instead of using a single equivalent-body, WAVDRAG calculates a series of equivalent-bodies, one for each roll angle. The total aircraft configuration wave drag is the integrated average of the equivalent-body wave drags through the full roll range of 360 degrees. WAVDRAG currently accepts up to 30 user-defined components containing a maximum of 50 contours as geometric input. Each contour contains a maximum of 50 points. The Mach number, angle-of-attack, and coordinates of angle-of-attack rotation are also input. The program warns of any fusiform-body line segments having a slope larger than the Mach angle. WAVDRAG calculates total drag and the wave-drag coefficient of the specified aircraft configuration. WAVDRAG is written in FORTRAN 77 for batch execution and has been implemented on a CDC CYBER 170 series computer with a central memory requirement of approximately 63K (octal) of 60 bit words. This program was developed in 1983.
    Keywords: AERODYNAMICS
    Type: LAR-13223
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  • 95
    Publication Date: 2011-08-24
    Description: An approximate inverse solution is presented for the nonequilibrium flow in the inviscid shock layer about a vehicle in hypersonic flight. The method is based upon a thin-shock-layer approximation and has the advantage of being applicable to both subsonic and supersonic regions of the shock layer. The relative simplicity of the method makes it ideally suited for programming on a digital computer with a significant reduction in storage capacity and computing time required by other more exact methods. Comparison of nonequilibrium solutions for an air mixture obtained by the present method is made with solutions obtained by two other methods. Additional cases are presented for entry of spherical nose cones into representative Venusian and Matrian atmospheres. A digital computer program written in FORTRAN language is presented that permits an arbitrary gas mixture to be employed in the solution. The effects of vibration, dissociation, recombination, electronic excitation, and ionization are included in the program.
    Keywords: AERODYNAMICS
    Type: LAR-11198
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  • 96
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    Publication Date: 2011-08-24
    Description: Small areas of high heat transfer and pressure can occur on a vehicle surface due to the influence of an impinging shock on the local flow. A method was needed to determine peak pressure and heating of these areas. This package is a system of computer programs designed to calculate two-dimensional shock interference patterns for six types of interference flows. Results also include properties of the inviscid flow field and the inviscid-viscous interaction at the surface along with peak pressure and peak heating at the impingement point. The six types of interference flow patterns considered are: 1) Type I interference patterns, occurring when two weak shocks of opposite families, BS (bow shock) and IS (impingment shock), intersect when the flow upstream of the impingement point is supersonic, or in the case of a blunt body, takes place well below the sonic point. 2) Type II interference pattern occurs when two shocks of opposite families (bow shock and impinging shock) intersect. Both shocks are weak as in type I, but are of such strength that in order to turn the flow, a Mach reflection must exist in the center of the flow field with an embedded subsonic region occurring between the intersection points (A & B) and the accompanying shear layers. Type II interference occurs on a blunt body when the impinging shock intersects the bow shock near the sonic point. 3) Type III shock interference pattern occurs when a weak impinging shock intersects a strong detached bow shock. On a blunt body the shock intersection occurs near or above the lower sonic point. 4) Type IV interference can occur when the impinging shock intersects a strong bow shock ahead of a subsonic flow region. On a blunt body this shock intersection is located between the lower sonic point and just above the body axis. The impinging shock causes a displacement of the bow shock and the formation of a supersonic jet that is embedded in the subsonic region. A jet bow shock is produced when the jet impinges on the surface, creating a small region with high stagnation heating. 5) Type V interference involves the interaction of two weak shocks of the same family. The interaction produces a shear layer, a supersonic jet, and a transmitted impinging shock. On a blunt body the shock interaction occurs near the upper sonic point. 6) Type VI interference involves the intersection of two weak shocks of the same family, which leads to an entirely supersonic flow field. This type of interference is important because it provides a means for predicting the onset of type V. Peak-heating correlations for laminar and turbulent shock-boundary-layer interactions are included in the programs for types I, II, V, and VI interference patterns. Heating correlations for laminar and turbulent reattaching shear layers obtained from separation studies are included in the program for type III interference. This program is written in FORTRAN IV for batch execution and has been implemented on a CDC 6000 Series computer. This program was developed in 1973.
    Keywords: AERODYNAMICS
    Type: LAR-11497
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  • 97
    Publication Date: 2011-08-24
    Description: A computer program has been written to obtain the wave and friction drag of configurations with bodies of revolution and fins. These inviscid flow fields are superimposed and the wave drag of the configuration is obtained by integration of the surface pressures. The friction drag is obtained from the viscous flow field of the body and a flat-plate friction analysis of the fins. The numerical solution of these flow fields, superposition, and integration to obtain total drag have been programmed for high-speed digital computation. A large portion of the input required by the program is involved with the description of the configuration geometry and the specific surface positions where pressures are to be evaluated. In addition to drag forces, an output is available whereby the pressure distributions on the body and fins can be obtained.
    Keywords: AERODYNAMICS
    Type: LAR-10935
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  • 98
    Publication Date: 2011-08-24
    Description: This paper is on the control of nonlinear-nonstationary vibration of a frame-stringer structure resulting from high levels of excitaation from a nearby supersonic jet exhaust. The structure exhibits periodic, chaotic, or random behaviors when forced by high-intensity sound from a supersonic jet exhaust with shock loading superimposed on the broadband response. The time history of the pressure, showing the rotation and flapping of the shock structure in the jet column due to large-scale instabilities, indicates that the response is not only nonlinear but also nonstationary. The acoustic pressure radiated by the structure also contains shocks and the formation of harmonics with distance. Control of the structural response is achieved by actively forcing the structure with an actuator at the shock oscillation frequency whose amplitude is locked into a self-control cycle. Results show that the peak power level is reduced by a factor of 63, or 18 dB. As a result, new broadband components emerge with at least four harmonics. At accelerating and decelerating supersonic speeds, the exhaust from the jet induces higher transient loading on the nearby flexible structure due to the occurence of multiple shocks from the jet.
    Keywords: AERODYNAMICS
    Type: AIAA Journal (ISSN 0001-1452); 32; 7; p. 1367-1376
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  • 99
    Publication Date: 2011-08-24
    Description: A Hughes communications satellite (INTELSAT series) belonging to the INTELSAT Organization was marooned in low-Earth orbit (LEO) on March 14, 1990, following failure of the Titan launch vehicle third stage to separate properly. The satellite, INTELSAT 6, was designed for service in geosynchronous orbit and contains several materials that are potentially susceptible to attack by atomic oxygen. Analysis showed that direct exposure of the silver interconnects in the satellite photovoltaic array to atomic oxygen in LEO was the key materials issue. Available data on atomic oxygen degradation of silver are limited and show high variance, so solar array configurations of the INTELSAT 6 type and individual interconnects were tested in ground-based facilities and during STS-41 (Space Shuttle Discovery, October 1990) as part of the ISAC flight experiment. Several materials for which little or no flight data exist were also tested for atomic oxygen reactivity. Dry lubricants, elastomers, and polymeric and inorganic materials were exposed to an oxygen atom fluence of 1.1 x 10(exp 20) atoms cm(exp 2). Many of the samples were selected to support Space Station Freedom design and decision making. This paper provides an overview of the ISAC flight experiment and a brief summary of results. In addition to new data on materials not before flown, ISAC provided data supporting the decision to rescue INTELSAT 6, which was successfully undertaken in May 1992.
    Keywords: ASTRONAUTICS (GENERAL)
    Type: Journal of Spacecraft and Rockets (ISSN 0022-4650); 31; 3; p. 475-481
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  • 100
    Publication Date: 2011-08-24
    Description: Previous studies have demonstrated that in vitro, alpha-crystallin can protect other lens proteins against extensive denaturation and aggregation. The mechanism of this protection involves preferential binding of the partially denatured protein to a central region of the native alpha-crystallin complex. To test whether a similar phenomenon might occur in vivo, a high molecular weight aggregate (HMWA) fraction was isolated from the aged bovine lens. Negative staining of this preparation revealed the presence of particles of 13-14 nm diameter, characteristic of alpha-crystallin. Immunolocalization of the same particles using antiserum specific for gamma- and beta-crystallins demonstrated preferential binding of these crystallins to the central region of the alpha-crystallin complex. Together, these results provide evidence that in the intact lens, the alpha-crystallins are functionally important molecular chaperones.
    Keywords: Life Sciences (General)
    Type: Experimental eye research (ISSN 0014-4835); Volume 58; 1; 9-15
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