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  • 1
    Publikationsdatum: 2021-03-03
    Beschreibung: Large earthquakes occurring worldwide have long been recognized to be non Poisson distributed, so involving some large scale correlation mechanism, which could be internal or external to the Earth. Till now, no statistically significant correlation of the global seismicity with one of the possible mechanisms has been demonstrated yet. In this paper, we analyze 20 years of proton density and velocity data, as recorded by the SOHO satellite, and the worldwide seismicity in the corresponding period, as reported by the ISC-GEM catalogue. We found clear correlation between proton density and the occurrence of large earthquakes (M 〉 5.6), with a time shift of one day. The significance of such correlation is very high, with probability to be wrong lower than 10-5. The correlation increases with the magnitude threshold of the seismic catalogue. A tentative model explaining such a correlation is also proposed, in terms of the reverse piezoelectric effect induced by the applied electric field related to the proton density. This result opens new perspectives in seismological interpretations, as well as in earthquake forecast.
    Beschreibung: Published
    Beschreibung: 11495
    Beschreibung: 7T. Variazioni delle caratteristiche crostali e precursori sismici
    Beschreibung: JCR Journal
    Schlagwort(e): correlation ; solar activity ; large earthquakes worldwide
    Repository-Name: Istituto Nazionale di Geofisica e Vulcanologia (INGV)
    Materialart: article
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  • 2
    Publikationsdatum: 2021-01-15
    Beschreibung: We reconstruct the composite dynamics of Mt. Vesuvius volcano in the period 2012–2019 from the study of ground deformation, seismicity, and geofluid (groundwater and fumarolic fluids) circulation and recognize complex spatio-temporal variations in these observables at medium (years) and short (months) time-scales. We interpret the observed patterns as the combined effect of structural changes affecting the volcanic edifice and variations of the dynamics of the hydrothermal system. In particular, we identify a change in the activity state of Mt. Vesuvius. After the activity reached minimum levels in 2014, the centroid of the surface manifestations migrated towards the SE. Episodic variations of co-seismic and aseismic deformation and fluid release, if analysed separately, would likely have been interpreted as pseudo-random oscillations of the background geophysical and geochemical signals. When organised in a comprehensive, multiparametric fashion, they shed light on the evolution of the volcano in 4D (x,y,z, time) space. These inferences play a crucial role in the formulation of civil protection scenarios for Mt. Vesuvius, a high risk, densely urbanized volcanic area which has never experienced unrest episodes in the modern era of instrumental volcanology.
    Beschreibung: Published
    Beschreibung: 965
    Beschreibung: 2V. Struttura e sistema di alimentazione dei vulcani
    Beschreibung: JCR Journal
    Schlagwort(e): recent dynamics ; Mt. Vesuvius ; investigations ; ground deformation ; seismicity ; geofluid circulation
    Repository-Name: Istituto Nazionale di Geofisica e Vulcanologia (INGV)
    Materialart: article
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  • 3
    Publikationsdatum: 2021-08-02
    Beschreibung: High Arctic ecosystems and Indigenous livelihoods are tightly linked and exposed to climate change, yet assessing their sensitivity requires a long-term perspective. Here, we assess the vulnerability of the North Water polynya, a unique seaice ecosystem that sustains the world’s northernmost Inuit communities and several keystone Arctic species. We reconstruct mid-tolate Holocene changes in sea ice, marine primary production, and little auk colony dynamics through multi-proxy analysis of marine and lake sediment cores. Our results suggest a productive ecosystem by 4400–4200 cal yrs b2k coincident with the arrival of the first humans in Greenland. Climate forcing during the late Holocene, leading to periods of polynya instability and marine productivity decline, is strikingly coeval with the human abandonment of Greenland from c. 2200–1200 cal yrs b2k. Our long-term perspective highlights the future decline of the North Water ecosystem, due to climate warming and changing sea-ice conditions, as an important climate change risk.
    Repository-Name: EPIC Alfred Wegener Institut
    Materialart: Article , isiRev
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  • 4
    Publikationsdatum: 2021-07-01
    Beschreibung: The evolution of past global ice sheets is highly uncertain. One example is the missing ice problem during the Last Glacial Maximum (LGM, 26 000-19 000 years before present) – an apparent 8-28 m discrepancy between far-field sea level indicators and modelled sea level from ice sheet reconstructions. In the absence of ice sheet reconstructions, researchers often use marine δ 18 O proxy records to infer ice volume prior to the LGM. We present a global ice sheet reconstruction for the past 80 000 years, called PaleoMIST 1.0, constructed inde- pendently of far-field sea level and δ 18 O proxy records. Our reconstruction is compatible with LGM far-field sea-level records without requiring extra ice volume, thus solving the missing ice problem. However, for Marine Isotope Stage 3 (57 000-29 000 years before present) - a pre-LGM period - our reconstruction does not match proxy-based sea level reconstructions, indicating the relationship between marine δ 18 O and sea level may be more complex than assumed.
    Repository-Name: EPIC Alfred Wegener Institut
    Materialart: Article , isiRev
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  • 5
    Publikationsdatum: 2021-03-08
    Beschreibung: Lake Baikal is inhabited by more than 300 endemic amphipod species, which are narrowly adapted to certain thermal niches due to the high interspecific competition. In contrast, the surrounding freshwater fauna is commonly represented by species with large‐scale distribution and high phenotypic thermal plasticity. Here, we investigated the thermal plasticity of the energy metabolism in two closely‐related endemic amphipod species from Lake Baikal (Eulimnogammarus verrucosus; stenothermal and Eulimnogammarus cyaneus; eurythermal) and the ubiquitous Holarctic amphipod Gammarus lacustris (eurythermal) by exposure to a summer warming scenario (6–23.6 °C; 0.8 °C d−1). In concert with routine metabolic rates, activities of key metabolic enzymes increased strongly with temperature up to 15 °C in E. verrucosus, whereupon they leveled off (except for lactate dehydrogenase). In contrast, exponential increases were seen in E. cyaneus and G. lacustris throughout the thermal trial (Q10‐values: 1.6–3.7). Cytochrome‐c‐oxidase, lactate dehydrogenase, and 3‐hydroxyacyl‐CoA dehydrogenase activities were found to be higher in G. lacustris than in E. cyaneus, especially at the highest experimental temperature (23.6 °C). Decreasing gene expression levels revealed some thermal compensation in E. cyaneus but not in G. lacustris. In all species, shifts in enzyme activities favored glycolytic energy generation in the warmth. The congruent temperature‐ dependencies of enzyme activities and routine metabolism in E. verrucosus indicate a strong feedback‐ regulation of enzymatic activities by whole organism responses. The species‐specific thermal reaction norms reflect the different ecological niches, including the spatial distribution, distinct thermal behavior such as temperature‐dependent migration, movement activity, and mating season.
    Repository-Name: EPIC Alfred Wegener Institut
    Materialart: Article , isiRev
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  • 6
    Publikationsdatum: 2021-06-30
    Repository-Name: EPIC Alfred Wegener Institut
    Materialart: Article , isiRev
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  • 7
    Publikationsdatum: 2021-06-16
    Beschreibung: Floating ice shelves are the Achilles’ heel of the Antarctic Ice Sheet. They limit Antarctica’s contribution to global sea level rise, yet they can be rapidly melted from beneath by a warming ocean. At Filchner-Ronne Ice Shelf, a decline in sea ice formation may increase basal melt rates and accelerate marine ice sheet mass loss within this century. However, the understanding of this tipping-point behavior largely relies on numerical models. Our new multi-annual observations from five hot-water drilled boreholes through Filchner-Ronne Ice Shelf show that since 2015 there has been an intensification of the density-driven ice shelf cavity-wide circulation in response to reinforced wind-driven sea ice formation in the Ronne polynya. Enhanced southerly winds over Ronne Ice Shelf coincide with westward displacements of the Amundsen Sea Low position, connecting the cavity circulation with changes in large-scale atmospheric circulation patterns as a new aspect of the atmosphere-ocean-ice shelf system.
    Repository-Name: EPIC Alfred Wegener Institut
    Materialart: Article , isiRev , info:eu-repo/semantics/article
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  • 8
    Publikationsdatum: 2021-07-27
    Beschreibung: The thecosome pteropods Limacina helicina and L. retroversa are important contributors to the zooplankton community in high-latitude environments but little is known about their distribution and life cycle under polar conditions. We collected the early life stages (〈 1 mm) of the thecosome population in 2012 and 2013 at a bi-weekly to monthly resolution in fjord highly influenced by Arctic waters as well as Atlantic inflows (Adventfjorden, Svalbard, 78°N), together with environmental parameters. L. retroversa only occurred episodically, in association with the inflow of Atlantic water, with low numbers and random size distributions. This suggests that this boreal species does not fulfill its life cycle in Adventfjorden. In contrast, young specimens of L. helicina were present during the entire study. Veligers hatched in late summer/autumn and measured 0.14 mm on average. They grew with rates of 0.0006 mm day− 1 over the 10–11 months of development. Only thereafter, growth accelerated by one order of magnitude and maximal rates were reached in autumn (0.0077 mm day− 1). Our results indicate that L. helicina reaches a size of 1 mm after approximately 1.5 years in Adventfjorden. We therefore suggest that L. helicina overwinters the first year as a small juvenile and that it needs at least 2 years to reach an adult size of 5 mm in Adventfjorden. This reveals an complex and delicate aspect of the life-cycle of L. helicina and further research is needed to determine if it makes the population especially vulnerable towards climate changes.
    Repository-Name: EPIC Alfred Wegener Institut
    Materialart: Article , isiRev
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  • 9
    Publikationsdatum: 2021-06-28
    Beschreibung: Efforts to collaboratively manage the risk of flooding are ultimately based on individuals learning about risks, the decision process, and the effectiveness of decisions made in prior situations. This article argues that much can be learned about a governance setting by explicitly evaluating the relationships through which influential individuals and their immediate contacts receive and send information to one another. We define these individuals as “brokers,” and the networks that emerge from their interactions as “learning spaces.” The aim of this article is to develop strategies to identify and evaluate the properties of a broker's learning space that are indicative of a collaborative flood risk management arrangement. The first part of this article introduces a set of indicators, and presents strategies to employ this list so as to systematically identify brokers, and compare their learning spaces. The second part outlines the lessons from an evaluation that explored cases in two distinct flood risk management settings in Germany. The results show differences in the observed brokers' learning spaces. The contacts and interactions of the broker in Baden‐Württemberg imply a collaborative setting. In contrast, learning space of the broker in North Rhine‐Westphalia lacks the same level of diversity and polycentricity.
    Beschreibung: Deutsche Forschungsgemeinschaft http://dx.doi.org/10.13039/501100001659
    Beschreibung: MWK Baden‐Württemberg
    Schlagwort(e): 333.91 ; brokerage ; collaborative water governance ; comanagement ; comparative analysis ; social networks
    Materialart: article
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  • 10
    Publikationsdatum: 2021-07-04
    Beschreibung: Most common machine learning (ML) algorithms usually work well on balanced training sets, that is, datasets in which all classes are approximately represented equally. Otherwise, the accuracy estimates may be unreliable and classes with only a few values are often misclassified or neglected. This is known as a class imbalance problem in machine learning and datasets that do not meet this criterion are referred to as imbalanced data. Most datasets of soil classes are, therefore, imbalanced data. One of our main objectives is to compare eight resampling strategies that have been developed to counteract the imbalanced data problem. We compared the performance of five of the most common ML algorithms with the resampling approaches. The highest increase in prediction accuracy was achieved with SMOTE (the synthetic minority oversampling technique). In comparison to the baseline prediction on the original dataset, we achieved an increase of about 10, 20 and 10% in the overall accuracy, kappa index and F‐score, respectively. Regarding the ML approaches, random forest (RF) showed the best performance with an overall accuracy, kappa index and F‐score of 66, 60 and 57%, respectively. Moreover, the combination of RF and SMOTE improved the accuracy of the individual soil classes, compared to RF trained on the original dataset and allowed better prediction of soil classes with a low number of samples in the corresponding soil profile database, in our case for Chernozems. Our results show that balancing existing soil legacy data using synthetic sampling strategies can significantly improve the prediction accuracy in digital soil mapping (DSM). Highlights Spatial distribution of soil classes in Iran can be predicted using machine learning (ML) algorithms. The synthetic minority oversampling technique overcomes the drawback of imbalanced and highly biased soil legacy data. When combining a random forest model with synthetic sampling strategies the prediction accuracy of the soil model improves significantly. The resulting new soil map of Iran has a much higher spatial resolution compared to existing maps and displays new soil classes that have not yet been mapped in Iran.
    Beschreibung: Alexander von Humboldt‐Stiftung http://dx.doi.org/10.13039/100005156
    Beschreibung: German Research Foundation http://dx.doi.org/10.13039/501100001659
    Beschreibung: Soil and Water Research Institute, Agricultural Research, Education and Extension Organization, Karaj, Iran
    Schlagwort(e): 631.4 ; covariates ; imbalanced data ; machine learning ; random forest ; soil legacy data
    Materialart: article
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  • 11
    Publikationsdatum: 2021-06-16
    Beschreibung: The application of biochar to agricultural soils to increase nutrient availability, crop production and carbon sequestration has gained increasing interest but data from field experiments on temperate, marginal soils are still under‐represented. In the current study, biochar, produced from organic residues (digestates) from a biogas plant, was applied with and without digestates at low (3.4 t ha−1) and intermediate (17.1 t ha−1) rates to two acidic and sandy soils in northern Germany that are used for corn (Zea mays L.) production. Soil nutrient availability, crop yields, microbial biomass and carbon dioxide (CO2) emissions from heterotrophic respiration were measured over two consecutive years. The effects of biochar application depended on the intrinsic properties of the two tested soils and the biochar application rates. Although the soils at the fallow site, with initially low nutrient concentrations, showed a significant increase in pH, soil nutrients and crop yield after low biochar application rates, a similar response was found at the cornfield site only after application of substantially larger amounts of biochar. The effect of a single dose of biochar at the beginning of the experiment diminished over time but was still detectable after 2 years. Whereas plant available nutrient concentrations increased after biochar application, the availability of potentially phytotoxic trace elements (Zn, Pb, Cd, Cr) decreased significantly, and although slight increases in microbial biomass carbon and heterotrophic CO2 fluxes were observed after biochar application, they were mostly not significant. The results indicate that the application of relatively small amounts of biochar could have positive effects on plant available nutrients and crop yields of marginal arable soils and may decrease the need for mineral fertilizers while simultaneously increasing the sequestration of soil organic carbon. Highlights A low rate of biochar increased plant available nutrients and crop yield on marginal soils. Biochar application reduced the availability of potentially harmful trace elements. Heterotrophic respiration showed no clear response to biochar application. Biochar application may reduce fertilizer need and increase carbon sequestration on marginal soils.
    Beschreibung: German Academic Exchange Service http://dx.doi.org/10.13039/501100001655
    Beschreibung: Institute Strategic Programme grants, “Soils to Nutrition”
    Schlagwort(e): 631.4 ; black carbon ; carbon sequestration ; corn ; digestate ; heterotrophic respiration ; marginal soils ; microbial biomass
    Materialart: article
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  • 12
    Publikationsdatum: 2021-06-27
    Beschreibung: Social inequalities lead to flood resilience inequalities across social groups, a topic that requires improved documentation and understanding. The objective of this paper is to attend to these differences by investigating self‐stated flood recovery across genders in Vietnam as a conceptual replication of earlier results from Germany. This study employs a regression‐based analysis of 1,010 respondents divided between a rural coastal and an urban community in Thua Thien‐Hue province. The results highlight an important set of recovery process‐related variables. The set of relevant variables is similar across genders in terms of inclusion and influence, and includes age, social capital, internal and external support after a flood, perceived severity of previous flood impacts, and the perception of stress‐resilience. However, women were affected more heavily by flooding in terms of longer recovery times, which should be accounted for in risk management. Overall, the studied variables perform similarly in Vietnam and Germany. This study, therefore, conceptually replicates previous results suggesting that women display slightly slower recovery levels as well as that psychological variables influence recovery rates more than adverse flood impacts. This provides an indication of the results' potentially robust nature due to the different socio‐environmental contexts in Germany and Vietnam.
    Schlagwort(e): 333.7 ; flood recovery ; resilience ; societal equity ; vulnerability
    Materialart: article
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  • 13
    Publikationsdatum: 2021-07-05
    Beschreibung: Nitrogen (N) fertilization is the major contributor to nitrous oxide (N2O) emissions from agricultural soil, especially in post‐harvest seasons. This study was carried out to investigate whether ryegrass serving as cover crop affects soil N2O emissions and denitrifier community size. A microcosm experiment was conducted with soil planted with perennial ryegrass (Lolium perenne L.) and bare soil, each with four levels of N fertilizer (0, 5, 10 and 20 g N m−2; applied as calcium ammonium nitrate). The closed‐chamber approach was used to measure soil N2O fluxes. Real‐time PCR was used to estimate the biomass of bacteria and fungi and the abundance of genes involved in denitrification in soil. The results showed that the presence of ryegrass decreased the nitrate content in soil. Cumulative N2O emissions of soil with grass were lower than in bare soil at 5 and 10 g N m−2. Fertilization levels did not affect the abundance of soil bacteria and fungi. Soil with grass showed greater abundances of bacteria and fungi, as well as microorganisms carrying narG, napA, nirK, nirS and nosZ clade I genes. It is concluded that ryegrass serving as a cover crop holds the potential to mitigate soil N2O emissions in soils with moderate or high NO3− concentrations. This highlights the importance of cover crops for the reduction of N2O emissions from soil, particularly following N fertilization. Future research should explore the full potential of ryegrass to reduce soil N2O emissions under field conditions as well as in different soils. Highlights This study was to investigate whether ryegrass serving as cover crop affects soil N2O emissions and denitrifier community size; Plant reduced soil N substrates on one side, but their root exudates stimulated denitrification on the other side; N2O emissions were lower in soil with grass than bare soil at medium fertilizer levels, and growing grass stimulated the proliferation of almost all the denitrifying bacteria except nosZ clade II; Ryegrass serving as a cover crop holds the potential to mitigate soil N2O emissions.
    Beschreibung: China Scholarship Council http://dx.doi.org/10.13039/501100004543
    Beschreibung: The National Science Project for University of Anhui Province
    Schlagwort(e): 551.9 ; 631.4 ; denitrification ; perennial ryegrass (Lolium perenne L.) ; soil bacteria ; soil CO2 emissions ; soil N2O emissions
    Materialart: article
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  • 14
    facet.materialart.
    Unbekannt
    Blackwell Publishing Ltd | Malden, US
    Publikationsdatum: 2021-07-04
    Beschreibung: High‐performance numerical codes are an indispensable tool for hydrogeologists when modeling subsurface flow and transport systems. But as they are written in compiled languages, like C/C++ or Fortran, established software packages are rarely user‐friendly, limiting a wider adoption of such tools. OpenGeoSys (OGS), an open‐source, finite‐element solver for thermo‐hydro‐mechanical–chemical processes in porous and fractured media, is no exception. Graphical user interfaces may increase usability, but do so at a dramatic reduction of flexibility and are difficult or impossible to integrate into a larger workflow. Python offers an optimal trade‐off between these goals by providing a highly flexible, yet comparatively user‐friendly environment for software applications. Hence, we introduce ogs5py, a Python‐API for the OpenGeoSys 5 scientific modeling package. It provides a fully Python‐based representation of an OGS project, a large array of convenience functions for users to interact with OGS and connects OGS to the scientific and computational environment of Python.
    Beschreibung: German Federal Environmental Foundation http://dx.doi.org/10.13039/100007636
    Beschreibung: Deutsche Forschungsgemeinschaft http://dx.doi.org/10.13039/501100001659
    Schlagwort(e): 551.49 ; hydrogeology ; subsurface flow ; modeling ; software
    Materialart: article
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  • 15
    Publikationsdatum: 2021-06-27
    Beschreibung: Transport processes that lead to exchange of mass between surface water and groundwater play a significant role for the ecological functioning of aquatic systems, for hydrological processes and for biogeochemical transformations. In this study, we present a novel integral modeling approach for flow and transport at the sediment–water interface. The model allows us to simultaneously simulate turbulent surface and subsurface flow and transport with the same conceptual approach. For this purpose, a conservative transport equation was implemented to an existing approach that uses an extended version of the Navier–Stokes equations. Based on previous flume studies which investigated the spreading of a dye tracer under neutral, losing and gaining flow conditions the new solver is validated. Tracer distributions of the experiments are in close agreement with the simulations. The simulated flow paths are significantly affected by in‐ and outflowing groundwater flow. The highest velocities within the sediment are found for losing condition, which leads to shorter residence times compared to neutral and gaining conditions. The largest extent of the hyporheic exchange flow is observed under neutral condition. The new solver can be used for further examinations of cases that are not suitable for the conventional coupled models, for example, if Reynolds numbers are larger than 10. Moreover, results gained with the integral solver provide high‐resolution information on pressure and velocity distributions at the rippled streambed, which can be used to improve flow predictions. This includes the extent of hyporheic exchange under varying ambient groundwater flow conditions.
    Beschreibung: Technische Universität Berlin, Germany
    Beschreibung: German Research Foundation http://dx.doi.org/10.13039/501100001659
    Schlagwort(e): 551.4 ; aquatic systems ; sediment-water interface ; transport model
    Materialart: article
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  • 16
    Publikationsdatum: 2021-07-05
    Beschreibung: Sustainable arable cropping relies on repeated liming. Yet, the associated increase in soil pH can reduce the availability of iron (Fe) to plants. We hypothesized that repeated liming, but not pedogenic processes such as lessivage (i.e., translocation of clay particles), alters the Fe cycle in Luvisol soil, thereby affecting Fe isotope composition in soils and crops. Hence, we analysed Fe concentrations and isotope compositions in soil profiles and winter rye from the long‐term agricultural experimental site in Berlin‐Dahlem, Germany, where a controlled liming trial with three field replicates per treatment has been conducted on Albic Luvisols since 1923. Heterogeneity in subsoil was observed at this site for Fe concentration but not for Fe isotope composition. Lessivage had not affected Fe isotope composition in the soil profiles. The results also showed that almost 100 years of liming lowered the concentration of the HCl‐extractable Fe that was potentially available for plant uptake in the surface soil (0–15 cm) from 1.03 (standard error (SE) 0.03) to 0.94 (SE 0.01) g kg−1. This HCl‐extractable Fe pool contained isotopically lighter Fe (δ56Fe = −0.05 to −0.29‰) than the bulk soil (δ56Fe = −0.08 to 0.08‰). However, its Fe isotope composition was not altered by the long‐term lime application. Liming resulted in relatively lower Fe concentrations in the roots of winter rye. In addition, liming led to a heavier Fe isotope composition of the whole plants compared with those grown in the non‐limed plots (δ56FeWholePlant_ + Lime = −0.12‰, SE 0.03 vs. δ56FeWholePlant_‐Lime = −0.21‰, SE 0.01). This suggests that the elevated soil pH (increased by one unit due to liming) promoted the Fe uptake strategy through complexation of Fe(III) from the rhizosphere, which favoured heavier Fe isotopes. Overall, the present study showed that liming and a related increase in pH did not affect the Fe isotope compositions of the soil, but may influence the Fe isotope composition of plants grown in the soil if they alter their Fe uptake strategy upon the change of Fe availability. Highlights Fe concentrations and stocks, but not Fe isotope compositions, were more heterogeneous in subsoil than in topsoil. Translocation of clay minerals did not result in Fe isotope fractionation in the soil profile of a Luvisol. Liming decreased Fe availability in topsoil, but did not affect its δ56Fe values. Uptake of heavier Fe isotopes by graminaceous crops was more pronounced at elevated pH.
    Beschreibung: Bundesministerium für Bildung und Forschung http://dx.doi.org/10.13039/501100002347
    Schlagwort(e): 551.9 ; liming ; plant‐available Fe pool in soil ; winter rye ; δ56Fe
    Materialart: article
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  • 17
    Publikationsdatum: 2021-08-16
    Beschreibung: The intensification of Northern Hemisphere glaciations at the end of the Pliocene epoch marks one of the most substantial climatic shifts of the Cenozoic. Despite global cooling, sea surface temperatures in the high latitude North Atlantic Ocean rose between 2.9–2.7 million years ago. Here we present sedimentary geochemical proxy data from the Gulf of Cadiz to reconstruct the variability of Mediterranean Outflow Water, an important heat source to the North Atlantic. We find evidence for enhanced production of Mediterranean Outflow from the mid-Pliocene to the late Pliocene which we infer could have driven a sub-surface heat channel into the high-latitude North Atlantic. We then use Earth System Models to constrain the impact of enhanced Mediterranean Outflow production on the northward heat transport in the North Atlantic. In accord with the proxy data, the numerical model results support the formation of a sub-surface channel that pumped heat from the subtropics into the high latitude North Atlantic. We further suggest that this mechanism could have delayed ice sheet growth at the end of the Pliocene.
    Repository-Name: EPIC Alfred Wegener Institut
    Materialart: Article , isiRev
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  • 18
    Publikationsdatum: 2021-09-22
    Beschreibung: A set of four magnitude Ml≥3.0 earthquakes including the magnitude Ml=3.7 mainshock of the seismic sequence hitting the Lake Constance, Southern Germany, area in July–August 2019 was studied by means of bulletin and waveform data collected from 86 seismic stations of the Central Europe-Alpine region. The frst single-event locations obtained using a uniform 1-D velocity model, and both fxed and free depths, showed residuals of the order of up±2.0 s, systematically afecting stations located in diferent areas of the study region. Namely, German stations to the northeast of the epicenters and French stations to the west exhibit negative residuals, while Italian stations located to the southeast are characterized by similarly large positive residuals. As a consequence, the epicentral coordinates were afected by a signifcant bias of the order of 4–5 km to the NNE. The locations were repeated applying a method that uses diferent velocity models for three groups of stations situated in diferent geological environments, obtaining more accurate locations. Moreover, the application of two methods of relative locations and joint hypocentral determination, without improving the absolute location of the master event, has shown that the sources of the four considered events are separated by distances of the order of one km both in horizontal coordinates and in depths. A particular attention has been paid to the geographical positions of the seismic stations used in the locations and their relationship with the known crustal features, such as the Moho depth and velocity anomalies in the studied region. Signifcant correlations between the observed travel time residuals and the crustal structure were obtained.
    Beschreibung: Published
    Beschreibung: 1163–1175
    Beschreibung: 1T. Struttura della Terra
    Beschreibung: 2TR. Ricostruzione e modellazione della struttura crostale
    Beschreibung: JCR Journal
    Repository-Name: Istituto Nazionale di Geofisica e Vulcanologia (INGV)
    Materialart: article
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  • 19
    Publikationsdatum: 2021-09-22
    Beschreibung: The Italian Apennines are among the most important sources of freshwater for several Italian regions. With evidences of deep CO2-rich fluids intruding into aquifers in the nearby central-southern Apennines, a thorough investigation into the geochemistry of groundwater became critical to ensure the water quality in the area. Here, we show the main hydrogeochemical processes occurring in the Matese Massif (MM) aquifer through the investigation of 98 water samples collected from springs and water wells. All waters were classified as HCO3 type with Ca dominance (from 50% up to 97%) and variable amount of Mg (from 1% up to 49%). A multivariate statistical approach through the application of the factor analysis (FA) highlighted three main hydrogeochemical processes: (i) water-carbonate rock interactions mostly enhanced in peripheral areas of the MM by CO2 deep degassing; (ii) addition of NaCl-rich components linked to recharging process and to water mixing processes of the groundwater with a thermal component relatively rich in Cl, Na, and CO2; (iii) anthropogenic activities influencing groundwater composition at the foothills of MM. Furthermore, the first detailed TDIC, pCO2, and δ13C-TDIC distribution maps of the MM area have been created, which track chemical and isotopic anomalies in several peripheral areas (Pratella, Ailano, and Telese) throughout the region. These maps systematically highlight that the greater the amount of dissolved carbon occurs the heavier the C isotope enrichment, especially in the peripheral areas. Conversely, spring waters emerging at higher altitudes within MM are only slightly mineralized and associated with δ13C-TDIC values mainly characterized by recharging processes with the addition of biogenic carbon during the infiltration process through the soil.
    Beschreibung: Published
    Beschreibung: 46614–46626
    Beschreibung: 6A. Geochimica per l'ambiente e geologia medica
    Beschreibung: 2IT. Laboratori analitici e sperimentali
    Beschreibung: JCR Journal
    Schlagwort(e): CO2 degassing; Factor analysis; Mineral springs; Total dissolved inorganic carbon; δ13C-TDIC ; 03.02. Hydrology ; 04.04. Geology
    Repository-Name: Istituto Nazionale di Geofisica e Vulcanologia (INGV)
    Materialart: article
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  • 20
    facet.materialart.
    Unbekannt
    Springer Nature
    In:  EPIC3Communications Earth & Environment, Springer Nature, 2(162), pp. 1-6
    Publikationsdatum: 2021-08-31
    Beschreibung: Geothermal heat flow in the polar regions plays a crucial role in understanding ice-sheet dynamics and predictions of sea level rise. Continental-scale indirect estimates often have a low spatial resolution and yield largest discrepancies in West Antarctica. Here we analyse geophysical data to estimate geothermal heat flow in the Amundsen Sea Sector of West Antarctica. With Curie depth analysis based on a new magnetic anomaly grid compilation, we reveal variations in lithospheric thermal gradients. We show that the rapidly retreating Thwaites and Pope glaciers in particular are underlain by areas of largely elevated geothermal heat flow, which relates to the tectonic and magmatic history of the West Antarctic Rift System in this region. Our results imply that the behavior of this vulnerable sector of the West Antarctic Ice Sheet is strongly coupled to the dynamics of the underlying lithosphere.
    Repository-Name: EPIC Alfred Wegener Institut
    Materialart: Article , isiRev
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    Format: application/pdf
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  • 21
    Publikationsdatum: 2021-09-29
    Beschreibung: Coping with the growing impacts of flooding in EU countries, a paradigm shift in flood management can be observed, moving from safety‐based towards risk‐based approaches and holistic perspectives. Flood resilience is a common denominator of most of the approaches. In this article, we present the ‘Flood Resilience Rose’ (FRR), a management tool to promote harmonised action towards flood resilience in European regions and beyond. The FRR is a result of a two‐step process. First, based on scientific concepts as well as analysis of relevant policy documents, we identified three ‘levels of operation’. The first level refers to the EU Floods Directive and an extended multi‐layer safety approach, comprising the four different layers of protection, prevention, preparedness and recovery, and related measures to be taken. This level is not independent but depends both on the institutional (second level) and the wider (third level) context. Second, we used surveys, semi‐structured interviews and group discussions during workshops with experts from Belgium, Denmark, Germany, the Netherlands and the United Kingdom to validate the definitions and the FRR's practical relevance. The presented FRR is thus the result of rigorous theoretical and practical consideration and provides a tool capable to strengthen flood risk management practice.
    Beschreibung: European Regional Development Fund http://dx.doi.org/10.13039/501100008530
    Schlagwort(e): 551.48 ; flood defence measures ; governance and institutions ; integrated flood risk management ; resilience
    Materialart: map
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  • 22
    Publikationsdatum: 2021-12-15
    Beschreibung: Succession of cold glacials and warm interglacials during the Quaternary results from large global climate responses to variable orbital configurations, accompanied by fluctuating greenhouse gas concentrations. Despite the influences of sea ice and atmospheric and ocean circulations in the Southern Ocean on atmospheric CO2 concentrations and climate, past changes in this region remain poorly documented. Here, we present the 800 ka deuterium excess record from the East Antarctica EPICA Dome C ice core, tracking sea surface temperature in evaporative regions of the Indian sector of the Southern Ocean from which moisture precipitated in East Antarctica is derived. We find that low obliquity leads to surface warming in evaporative moisture source regions during each glacial inception, although this relative temperature increase is counterbalanced by global cooling during glacial maxima. Links between the two regions during interglacials depends on the existence of a temperature maximum at the interglacial onset. In its absence, temperature maxima in the evaporative moisture source regions and in East Antarctica were synchronous. For the other interglacials, temperature maxima in the source areas lag early local temperature maxima by several thousand years, probably because of a change in the position of the evaporative source areas.
    Repository-Name: EPIC Alfred Wegener Institut
    Materialart: Article , isiRev
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  • 23
    Publikationsdatum: 2021-12-15
    Beschreibung: Over the past decades, two key grazers in the Southern Ocean (SO), krill and salps, have experienced drastic changes in their distribution and abundance, leading to increasing overlap of their habitats. Both species occupy different ecological niches and long-term shifts in their distributions are expected to have cascading effects on the SO ecosystem. However, studies directly comparing krill and salps are lacking. Here, we provide a direct comparison of the diet and fecal pellet composition of krill and salps using 18S metabarcoding and fatty acid markers. Neither species’ diet reflected the composition of the plankton community, suggesting that in contrast to the accepted paradigm, not only krill but also salps are selective feeders. Moreover, we found that krill and salps had broadly similar diets, potentially enhancing the competition between both species. This could be augmented by salps’ ability to rapidly reproduce in favorable conditions, posing further risks to krill populations.
    Repository-Name: EPIC Alfred Wegener Institut
    Materialart: Article , peerRev
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  • 24
    Publikationsdatum: 2021-01-01
    Digitale ISSN: 0718-1876
    Thema: Wirtschaftswissenschaften
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  • 25
    Publikationsdatum: 2021-01-01
    Digitale ISSN: 0718-1876
    Thema: Wirtschaftswissenschaften
    Standort Signatur Erwartet Verfügbarkeit
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  • 26
    Publikationsdatum: 2021-01-01
    Digitale ISSN: 0718-1876
    Thema: Wirtschaftswissenschaften
    Standort Signatur Erwartet Verfügbarkeit
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  • 27
    Publikationsdatum: 2021-01-01
    Digitale ISSN: 0718-1876
    Thema: Wirtschaftswissenschaften
    Standort Signatur Erwartet Verfügbarkeit
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  • 28
    Publikationsdatum: 2021-01-01
    Digitale ISSN: 0718-1876
    Thema: Wirtschaftswissenschaften
    Standort Signatur Erwartet Verfügbarkeit
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  • 29
  • 30
    Publikationsdatum: 2021-08-20
    Beschreibung: The Kadomtsev–Petviashvili equation is known to be the leading term of a semi-infinite hierarchy of integrable equations with evolutions given by times with positive numbers. Here, we introduce new hierarchy directed to negative numbers of times. The derivation of such systems, as well as the corresponding hierarchy, is based on the commutator identities. This approach enables introduction of linear differential equations that admit lifts up to nonlinear integrable ones by means of the special dressing procedure. Thus, one can construct not only nonlinear equations, but corresponding Lax pairs as well. The Lax operator of this evolution coincides with the Lax operator of the “positive” hierarchy. We also derive (1 + 1)-dimensional reductions of equations of this hierarchy.
    Digitale ISSN: 2227-7390
    Thema: Mathematik
    Standort Signatur Erwartet Verfügbarkeit
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  • 31
    Publikationsdatum: 2021-08-20
    Beschreibung: Among industrially important pyridoxal-5’-phosphate (PLP)-dependent transaminases of fold type IV D-amino acid transaminases are the least studied. However, the development of cascade enzymatic processes, including the synthesis of D-amino acids, renewed interest in their study. Here, we describe the identification, biochemical and structural characterization of a new D-amino acid transaminase from Haliscomenobacter hydrossis (Halhy). The new enzyme is strictly specific towards D-amino acids and their keto analogs; it demonstrates one of the highest rates of transamination between D-glutamate and pyruvate. We obtained the crystal structure of the Halhy in the holo form with the protonated Schiff base formed by the K143 and the PLP. Structural analysis revealed a novel set of the active site residues that differ from the key residues forming the active sites of the previously studied D-amino acids transaminases. The active site of Halhy includes three arginine residues, one of which is unique among studied transaminases. We identified critical residues for the Halhy catalytic activity and suggested functions of the arginine residues based on the comparative structural analysis, mutagenesis, and molecular modeling simulations. We suggested a strong positive charge in the O-pocket and the unshaped P-pocket as a structural code for the D-amino acid specificity among transaminases of PLP fold type IV. Characteristics of Halhy complement our knowledge of the structural basis of substrate specificity of D-amino acid transaminases and the sequence-structure-function relationships in these enzymes.
    Digitale ISSN: 1420-3049
    Thema: Chemie und Pharmazie
    Standort Signatur Erwartet Verfügbarkeit
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  • 32
    Publikationsdatum: 2021-08-19
    Beschreibung: Non-persistent viruses classically cause transient, acute infections triggering immune responses aimed at the elimination of the pathogen. Successful viruses evolved strategies to manipulate and evade these anti-viral defenses. Symptoms during the acute phase are often linked to dysregulated immune responses that disappear once the patient recovers. In some patients, however, symptoms persist or new symptoms emerge beyond the acute phase. Conditions resulting from previous transient infection are termed post-acute sequelae (PAS) and were reported for a wide range of non-persistent viruses such as rota-, influenza- or polioviruses. Here we provide an overview of non-persistent viral pathogens reported to be associated with diverse PAS, among them chronic fatigue, auto-immune disorders, or neurological complications and highlight known mechanistic details. Recently, the emergence of post-acute sequelae of COVID-19 (PASC) or long COVID highlighted the impact of PAS. Notably, PAS of non-persistent infections often resemble symptoms of persistent viral infections, defined by chronic inflammation. Inflammation maintained after the acute phase may be a key driver of PAS of non-persistent viruses. Therefore, we explore current insights into aberrant activation of innate immune signaling pathways in the post-acute phase of non-persistent viruses. Finally, conclusions are drawn and future perspectives for treatment and prevention of PAS are discussed.
    Digitale ISSN: 2073-4409
    Thema: Biologie
    Standort Signatur Erwartet Verfügbarkeit
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  • 33
    Publikationsdatum: 2021-08-20
    Beschreibung: Dispersion of lead (Pb) in mine wastes was simulated for reproducing Pb contamination of soil in Kabwe District, Zambia. Local weather data of year 2019 were monitored in situ and used for the simulations. The plume model, weak puff model, and no puff model were adopted for calculation of Pb dispersion under different wind conditions. The results showed that Pb dispersion from the Kabwe mine was directly affected by wind directions and speeds in the dry season, although it was not appreciably affected in the rainy season. This may be because the source strength is lower in the rainy season due to higher water content of the surface. This indicates that Pb dispersion patterns depend on the season. In addition, the distribution of the amount of deposited Pb-bearing soils around the mine corresponded to the distribution of Pb contents in soils. These results suggest that Pb contamination in soils primarily results from dispersion of fine mine wastes.
    Digitale ISSN: 2075-163X
    Thema: Geologie und Paläontologie
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  • 34
    Publikationsdatum: 2021-08-19
    Beschreibung: This paper proposes an equivalent circuit model to obtain the transient electrical stress quantitatively in medium voltage medium frequency transformers in modern power electronics. To verify this model, transient simulation is performed on a 1.5 kV/1 kHz transformer, revealing voltage overshoot quantitatively between turns and layers of the transformer’s HV winding. Effects of rise time of the input pulse voltage, stray capacitance of the winding insulation, and their interactions on the voltage overshot magnitude are presented. With these results, we propose limiting the voltage overshoot and, thereafter, enhancing medium voltage medium frequency transformer’s insulation capability, which throws light on the transformer’s insulation design. Additionally, guidance on the future studies on aging and endurance lifetime of the medium voltage medium frequency transformer’s insulation could be given.
    Digitale ISSN: 1996-1073
    Thema: Energietechnik
    Standort Signatur Erwartet Verfügbarkeit
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  • 35
    Publikationsdatum: 2021-08-20
    Beschreibung: Since reinforced concrete (RC) buildings have long service life, cutout openings are generally needed in their load-bearing walls as a sustainable solution in order to meet new requirements of their users. However, the cutout openings decrease the load-bearing capacity of the walls, which may result in the failure of the buildings. In this paper, we investigate the possibility of making a door opening in a load-bearing RC wall of an existing building in Gävle in Sweden. The wall studied in the current paper rests on two individual supports at its two ends; thus, it is considered as a deep beam. However, it is called an examined wall (EW) here. The StruSoft FEM-Design software is used in this study to model, analyze, and design the building based on the Eurocodes and Swedish national annex. The potential need for the EW to be strengthened when the cutout opening is made is also evaluated. It is concluded that strengthening the EW with cutout opening is needed. Different strengthening solutions are proposed for the EW. Moreover, the situation of the EW with the solutions is assessed with regard to the utilization ratio, deflection, and weight. Consequently, it is demonstrated that the proposed strengthening solutions function well for the EW.
    Digitale ISSN: 2075-5309
    Thema: Architektur, Bauingenieurwesen, Vermessung
    Standort Signatur Erwartet Verfügbarkeit
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  • 36
    Publikationsdatum: 2021-08-20
    Print ISSN: 1001-0602
    Digitale ISSN: 1748-7838
    Thema: Biologie , Medizin
    Publiziert von Springer Nature
    Standort Signatur Erwartet Verfügbarkeit
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  • 37
    Publikationsdatum: 2021-08-19
    Beschreibung: In the current era of a strongly competitive business environment, it is more difficult for companies to attract customers. Consumer neuroscience has growing potential here, as it reveals internal consumer preferences by using innovative methods and tools, which can effectively examine consumer behavior and attract new customers. In particular, smell has a great ability to subconsciously influence customers and, thus, support profitability. This paper examines the importance of consumer neuroscience and its modern technologies used for exploring human perceptions to influence customers and benefit from the aromatization of business spaces. We focused our analysis on various service sectors. Despite the potential of the examined issue, there are a limited number of studies in the field of service providers that use neuroscience tools to examine the effect of aromas on human emotions. Most studies took place in laboratory conditions, and the used methodological procedures varied widely. Our analysis showed that, in spite of the positive impact of aromatization in the majority of aromatized spaces, service companies still do not use the potential of consumer neuroscience and aroma marketing to a sufficient degree. Innovative methods and tools, in particular, are still very underused.
    Digitale ISSN: 2076-3417
    Thema: Allgemeine Naturwissenschaft
    Standort Signatur Erwartet Verfügbarkeit
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  • 38
    Publikationsdatum: 2021-08-20
    Beschreibung: The Kuroshio is the strongest warm current in the western North Pacific, which plays a crucial role in climate and human activities. In terms of this, the accurate acquisition of ocean surface current velocity and direction in the Kuroshio region is of great research value. Gaofen-3 synthetic aperture radar (SAR) provides data support for the study of ocean surface current measurements in the Kuroshio region, but no relevant experimental result has been published yet. In this paper, four available stripmap mode SARs’ data acquired by Gaofen-3 in the Kuroshio region are used for measuring the ocean surface current field. In general, the Doppler centroid anomaly (DCA) estimation is a common method to infer ocean surface currents from single-antenna stripmap data, but only the radial velocity component can be retrieved. In order to measure current vectors, a novel method combining the sub-aperture processing and the least squares (LS) technology is suggested and demonstrated by applying to the Gaofen-3 SAR data processing. The experiment’s results agree well with model-derived ocean current data, indicating that the Gaofen-3 SAR has the capability to accurately retrieve the ocean surface current field in the Kuroshio region and motivate further research by providing more data.
    Digitale ISSN: 2076-3417
    Thema: Allgemeine Naturwissenschaft
    Standort Signatur Erwartet Verfügbarkeit
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  • 39
    Publikationsdatum: 2021-08-20
    Beschreibung: In 2007 and 2009 the regulatory approval of the first-in-class complement inhibitor Eculizumab has revolutionized the clinical management of two rare, life-threatening clinical conditions: paroxysmal nocturnal hemoglobinuria (PNH) and atypical hemolytic uremic syndrome (aHUS). While being completely distinct diseases affecting blood cells and the glomerulus, PNH and aHUS remarkably share several features in their etiology and clinical presentation. An imbalance between complement activation and regulation at host surfaces underlies both diseases precipitating in severe thrombotic events that are largely resistant to anti-coagulant and/or anti-platelet therapies. Inhibition of the common terminal complement pathway by Eculizumab prevents the frequently occurring thrombotic events responsible for the high mortality and morbidity observed in patients not treated with anti-complement therapy. While many in vitro and ex vivo studies elaborate numerous different molecular interactions between complement activation products and hemostasis, this review focuses on the clinical evidence that links these two fields in humans. Several non-infectious conditions with known complement involvement are scrutinized for common patterns concerning a prothrombotic statues and the occurrence of certain complement activation levels. Next to PNH and aHUS, germline encoded CD59 or CD55 deficiency (the latter causing the disease Complement Hyperactivation, Angiopathic thrombosis, and Protein-Losing Enteropathy; CHAPLE), autoimmune hemolytic anemia (AIHA), (catastrophic) anti-phospholipid syndrome (APS, CAPS) and C3 glomerulopathy are considered. Parallels and distinct features among these conditions are discussed against the background of thrombosis, complement activation, and potential complement diagnostic and therapeutic avenues.
    Print ISSN: 0006-4971
    Digitale ISSN: 1528-0020
    Thema: Biologie , Medizin
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  • 40
    Publikationsdatum: 2021-08-20
    Beschreibung: Objectives N-Terminal pro Brain Natriuretic Peptide (NT-proBNP) is a diagnostic marker for heart failure and a prognostic factor for cardiovascular disease (CVD). The aim of this study was to examine the association of socioeconomic position (SEP) with NT-proBNP while assessing sex-differences and the impact of CVD risk factors and prevalent CVD on the association. Methods Baseline data of 4598 participants aged 45–75 years of the Heinz Nixdorf Recall Study were used. Income and education were used as SEP indicators. Age- and sex-adjusted linear regression models were fitted to calculate effect size estimates and 95% confidence intervals (95%-CIs) for the total effect of SEP indicators on NT-proBNP, while potential mediation was assessed by additionally accounting for traditional CVD risk factors (i.e., systolic blood pressure, HDL cholesterol, LDL cholesterol, diabetes, anti-hypertensive medication, lipid-lowering medication, BMI, current smoking). Education and income were included separately in the models. Results With an age- and sex-adjusted average change in NT-proBNP of -6.47% (95%-CI: -9.91; -2.91) per 1000€, the association between income and NT-proBNP was more pronounced compared to using education as a SEP indicator (-0.80% [95%-CI: -1.92; 0.32] per year of education). Sex-stratified results indicated stronger associations in men (-8.43% [95%-CI: -13.21; -3.38] per 1000€; -1.63% [95%-CI: -3.23; -0.001] per year of education) compared to women (-5.10% [95%-CI: -9.82; -0.01] per 1000€; -1.04% [95%-CI: -2.59; 0.50] per year of education). After adjusting for CVD risk factors some of the observed effect size estimates were attenuated, while the overall association between SEP indicators and NT-proBNP was still indicated. The exclusion of participants with prevalent coronary heart disease or stroke did not lead to a substantial change in the observed associations. Conclusions In the present study associations of education and income with NT-proBNP were observed in a population-based study sample. Only parts of the association were explained by traditional CVD risk factors, while there were substantial sex-differences in the strength of the observed association. Overt coronary heart disease or stroke did not seem to trigger the associations.
    Digitale ISSN: 1932-6203
    Thema: Medizin , Allgemeine Naturwissenschaft
    Publiziert von Public Library of Science
    Standort Signatur Erwartet Verfügbarkeit
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  • 41
    Publikationsdatum: 2021-08-20
    Beschreibung: The maned wolf (Chrysocyon brachyurus) is an induced ovulator. Though the mechanism of ovulation induction remains unknown, it is suspected to be urinary chemical signals excreted by males. This study assessed volatile organic compounds (VOCs) in weekly urine samples across 5 months from 13 maned wolves (6 intact males, 1 neutered male, 6 females) with the goal of identifying VOCs that are differentially expressed across sex, reproductive status, and pairing status. Solid-phase microextraction (SPME) and gas chromatography-mass spectrometry (GC-MS) were used to extract and separate VOCs that were identified via spectral matching with authentic standards, with spectral libraries, or with new software that further matches molecular fragment structures with mass spectral peaks. Two VOCs were present across all 317 urine samples: 2,5-dimethyl pyrazine and 2-methyl-6-(1-propenyl)-pyrazine. Fifteen VOCs differed significantly (Adj. P 〈 0.001 and |log2 fold change| 〉2.0) between intact males and females. Using partial least squares-discriminant analysis, the compounds with the highest importance to the sex classification were delta-decalactone, delta-dodecalactone, and bis(prenyl) sulfide. Sixty-two VOCs differed between intact males and the neutered male. Important classifier compounds were 3-ethyl 2,5-dimethyl pyrazine, 2-methyl-6-(1-propenyl)-pyrazine, and tetrahydro-2-isopentyl-5-propyl furan. Several VOCs established as important here have been implicated in reproductive communication in other mammals. This study is the most robust examination of differential expression in the maned wolf thus far and provides the most comprehensive analysis of maned wolf urinary VOCs to date, increasing the sample size substantially over previous chemical communication studies in this species. New data analysis software allowed for the identification of compounds in the hormone-producing mevalonate pathway which were previously unreported in maned wolf urine. Several putative semiochemicals were identified as good candidates for behavioral bioassays to determine their role in maned wolf reproduction, and specifically in ovulation induction.
    Digitale ISSN: 1932-6203
    Thema: Medizin , Allgemeine Naturwissenschaft
    Publiziert von Public Library of Science
    Standort Signatur Erwartet Verfügbarkeit
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  • 42
    Publikationsdatum: 2021-08-20
    Beschreibung: The C1q/TNF-related protein 3 (CTRP3) represents a pleiotropic adipokine reciprocally associated with obesity and type 2 diabetes mellitus and exhibits anti-inflammatory properties in relation to lipopolysaccharides (LPS)-mediated effects in adipocytes, as well as monocytes/macrophages. Here, we focused on the influence of CTRP3 on LPS-mediated effects in endothelial cells in order to expand the understanding of a possible anti-inflammatory function of CTRP3 in a setting of endotoxemia. An organ- and tissue-specific expression analysis by real-time PCR revealed a considerable Ctrp3 expression in various adipose tissue compartments; however, higher levels were detected in the aorta and in abundantly perfused tissues (bone marrow and the thyroid gland). We observed a robust Ctrp3 expression in primary endothelial cells and a transient upregulation in murine endothelial (MyEND) cells by LPS (50 ng/mL). In MyEND cells, CTRP3 inhibited the LPS-induced expression of interleukin (Il)-6 and the tumor necrosis factor (Tnf)-α, and suppressed the LPS-dependent expression of the major endothelial adhesion molecules Vcam-1 and Icam-1. The LPS-induced adhesion of monocytic cells to an endothelial monolayer was antagonized by CTRP3. In C57BL/6J mice with an LPS-induced systemic inflammation, exogenous CTRP3 did not affect circulating levels of TNF-α, ICAM-1, and VCAM-1. In conclusion, we characterized CTRP3 beyond its function as an adipokine in a setting of vascular inflammation. CTRP3 inhibited LPS-induced endothelial expression of adhesion molecules and monocyte cell adhesion, indicating an important vascular anti-inflammatory role for CTRP3 in endotoxemia.
    Digitale ISSN: 2073-4409
    Thema: Biologie
    Standort Signatur Erwartet Verfügbarkeit
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  • 43
    Publikationsdatum: 2021-08-20
    Beschreibung: The development of an efficient pretreatment, prior to enzymatic hydrolysis, is a good strategy for the sustainable use of refractory fish byproducts. This study compared hydrothermal pretreatments at 159 °C for 2 min, followed by water extraction (steam explosion-assisted extraction, SE) and 121 °C for 70 min (hot-pressure extraction, HPE), for the recovery of proteins from fish backbones. The effect of enzymatic hydrolysis on the properties of the obtained fish bone protein (FBP) was also evaluated. The results demonstrated that FBP had high contents of protein (81.09–84.88 g/100 g) and hydroxyproline (70–82 residues/1000 residues). After hydrolysis with Flavourzyme, for 3 h, the FBP hydrolysates that were pretreated with SE (SFBP-H) exhibited a better degree of hydrolysis (DH) and nitrogen recovery (NR), and a higher level of umami taste free amino acids (151.50 mg/100 mL), compared with the HPE-treated samples. The obtained SFBP-H mainly distributed below 3000 Da and had strong scavenging effects on 1,1-diphenyl-2-picrylhydrazy (DPPH) (IC50 = 4.24 mg/mL) and 2,2-azino-bis(3-ethylbenzothiazoline-6-sulphonic acid) (ABTS) (IC50 = 1.93 mg/mL) radicals. Steam explosion-assisted extraction is a promising route for recovering proteins from native fish bone materials, and improving the flavor and antioxidant activity of the hydrolysates.
    Digitale ISSN: 2304-8158
    Thema: Chemie und Pharmazie
    Standort Signatur Erwartet Verfügbarkeit
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  • 44
    Publikationsdatum: 2021-08-19
    Beschreibung: Since mineral supplements for horses commonly contain macro minerals, although the requirement for such is usually covered by roughage-based diets, the aim of this study was to investigate the effects of different dietary calcium levels on mineral serum concentrations and bone metabolism. The trial was conducted in 30 young warmblood stallions (2–3 years) that were divided into two groups for a five-month feeding trial. The groups were fed a hay- and oat-based diet and were either supplied with high (Ca-High) or moderate (Ca-Moderate) calcium excess. While in Ca-High calcium supply was about 2–2.5-fold of the requirement, in Ca-Moderate calcium requirements were slightly surpassed (1.5–1.6-fold). In order to monitor the effects of the different calcium supply, blood samples were taken during the trial and analysed for levels of macro and trace elements as well as concentrations of two bone markers. In Ca-Moderate a trend towards higher phosphorus serum levels compared to Ca-High was observed which was significant at the end of the trial (p = 0.0002). Furthermore, results showed no influence of the diet on bone markers. Results support the idea that forage-based rations for horses do not necessarily have to be supplemented with macro minerals but with trace elements.
    Digitale ISSN: 2076-2615
    Thema: Biologie , Land- und Forstwirtschaft, Gartenbau, Fischereiwirtschaft, Hauswirtschaft
    Standort Signatur Erwartet Verfügbarkeit
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  • 45
    Publikationsdatum: 2021-08-20
    Beschreibung: COVID-19 might have long-term mental health impacts. We aim to investigate the longitudinal changes in mental problems from initial COVID-19 peak to its aftermath among general public in China. Depression, anxiety and insomnia were assessed among a large-sample nationwide cohort of 10,492 adults during the initial COVID-19 peak (28 February 2020 to 11 March 2020) and its aftermath (8 July 2020 to 8 August 2020) using the Patient Health Questionnaire-9, Generalized Anxiety Disorder-7, and Insomnia Severity Index. We used generalized estimating equations and linear mixed models to explore factors associated with long-term mental health symptoms during COVID-19. During the five months, mental health symptoms remained consistently elevated (baseline 46.4%; follow-up 45.1%). Long-term depression, anxiety and insomnia were associated with several personal and work-related factors including quarantine (adjusted OR for any mental health symptoms 1.31, 95%CI 1.22–1.41, p 〈 0.001), increases in work burden after resuming work (1.77, 1.65–1.90, p 〈 0.001), occupational exposure risk to COVID-19 (1.26, 1.14–1.40, p 〈 0.001) and living in places severely affected by initial COVID-19 peak (1.21, 1.04–1.41, p = 0.01) or by a COVID-19 resurgence (1.38, 1.26–1.50, p 〈 0.001). Compliance with self-protection measures, such as wearing face masks (0.74, 0.61–0.90, p = 0.003), was associated with lower long-term risk of mental problems. The findings reveal a pronounced and prolonged mental health burden from the initial COVID-19 peak through to its aftermath in China. We should regularly monitor the mental health status of vulnerable populations throughout COVID-19.
    Print ISSN: 1661-7827
    Digitale ISSN: 1660-4601
    Thema: Energietechnik , Medizin
    Standort Signatur Erwartet Verfügbarkeit
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  • 46
    Publikationsdatum: 2021-08-19
    Beschreibung: Low-cost air quality stations can provide useful data that can offer a complete picture of urban air quality dynamics, especially when integrated with daily measurements from reference air quality stations. However, the success of such deployment depends on the measurement accuracy and the capability of resolving spatial and temporal gradients within a spatial domain. In this work, an ensemble of three low-cost stations named “AirQino” was deployed to monitor particulate matter (PM) concentrations over three different sites in an area affected by poor air quality conditions. Data of PM2.5 and PM10 concentrations were collected for about two years following a protocol based on field calibration and validation with a reference station. Results indicated that: (i) AirQino station measurements were accurate and stable during co-location periods over time (R2 = 0.5–0.83 and RMSE = 6.4–11.2 μg m−3; valid data: 87.7–95.7%), resolving current spatial and temporal gradients; (ii) spatial variability of anthropogenic emissions was mainly due to extensive use of wood for household heating; (iii) the high temporal resolution made it possible to detect time occurrence and strength of PM10 concentration peaks; (iv) the number of episodes above the 1-h threshold of 90 μg m−3 and their persistence were higher under urban and industrial sites compared to the rural area.
    Digitale ISSN: 2073-4433
    Thema: Geologie und Paläontologie
    Standort Signatur Erwartet Verfügbarkeit
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  • 47
    Publikationsdatum: 2021-08-20
    Beschreibung: Retinal dystrophies (RD) are clinically and genetically heterogenous disorders showing mutations in over 270 disease-associated genes. Several millions of people worldwide are affected with different types of RD. Studying the relevance of disease-associated sequence alterations will assist in understanding disorders and may lead to the development of therapeutic approaches. Here, we established a whole exome sequencing (WES) pipeline to rapidly identify disease-associated mutations in patients. Sanger sequencing was applied to identify deep-intronic variants and to verify the co-segregation of WES results within families. We analyzed 26 unrelated patients with different syndromic and non-syndromic clinical manifestations of RD. All patients underwent ophthalmic examinations. We identified nine novel disease-associated sequence variants among 37 variants identified in total. The sequence variants located to 17 different genes. Interestingly, two cases presenting with Stargardt disease carried deep-intronic variants in ABCA4. We have classified 21 variants as pathogenic variants, 4 as benign/likely benign variants, and 12 as variants of uncertain significance. This study highlights the importance of WES-based mutation analyses in RD patients supporting clinical decisions, broadly based genetic diagnosis and support genetic counselling. It is essential for any genetic therapy to expand the mutation spectrum, understand the genes’ function, and correlate phenotypes with genotypes.
    Digitale ISSN: 2073-4425
    Thema: Biologie
    Standort Signatur Erwartet Verfügbarkeit
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  • 48
    Publikationsdatum: 2021-08-20
    Beschreibung: Developments in the design of wind turbines with augmentation are advancing around the globe with the goal of generating electricity close to the user in built-up areas. This is certain to help lessen the power generation load as well as distribution and transmission network costs by reducing the distance between the user and the power source. The main objectives driving the development and advancement of vertical-axis wind turbines are increasing the power coefficient and the torque coefficient by optimizing the upstream wind striking on the rotor blades. Unlike horizontal-axis wind turbines, vertical axis turbines generate not only positive torque but also negative torque during operation. The negative torque generated by the returning blade is a key issue for vertical-axis wind turbines (VAWTs) that is counterproductive. Installation of wind deflectors for flow augmentation helps to reduce the negative torque generated by the returning blades as well as enhance the positive torque by creating a diversion in the upstream wind towards the forwarding blade during operation. This paper reviews various designs, experiments, and CFD simulations of wind deflectors reported to date. Optimization techniques for VAWTs incorporating wind deflectors are discussed in detail. The main focus of the review was on the installation position and orientation of the deflectors and their potential contribution to increasing the power coefficient. Topics for future study are suggested in the conclusion section of the paper.
    Digitale ISSN: 1996-1073
    Thema: Energietechnik
    Standort Signatur Erwartet Verfügbarkeit
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  • 49
    Publikationsdatum: 2021-08-20
    Beschreibung: Exploring differences in clinical outcomes based on race and origin among patients hospitalized for COVID-19 is a controversial issue. The ALC COVID-19 Registry includes all confirmed COVID-19 patients admitted to hospital from 3 March 2020 to 17 December 2020. The data were obtained from electronic health records in order to evaluate the differences in the clinical features and outcomes among European and Latin American patients. The follow-ups occurred after 156 days. A propensity score weighting (PSW) logistic regression model was used to estimate the odds ratio (OR, 95% CI) for Latin American origin and outcome associations. Of the 696 patients included, 46.7% were women, with a median age of 65 (IQR 53–67) years, 614 (88.2%) were European, and 82 (11.8%) were Latin American. Latin American patients were younger, with fewer comorbidities, and a higher incidence of extensive pneumonia. After adjusting for residual confounders, Latin American origin was not associated with an increased risk of death (PSW OR 0.85 (0.23–3.14)) or with the need for invasive mechanical ventilation (PSW OR 0.35 (0.12–1.03)). Latin American origin was associated with a shorter hospital stay, but without differences in how long the patient remained on mechanical ventilation. In a public healthcare system, the rates of death or mechanical ventilation in severe COVID-19 cases were found to be comparable between patients of European and Latin American origins.
    Digitale ISSN: 2076-2607
    Thema: Biologie
    Standort Signatur Erwartet Verfügbarkeit
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  • 50
    Publikationsdatum: 2021-08-19
    Beschreibung: The huge energy potential of Enhanced Geothermal Systems (EGS) makes them perspective sources of non-intermittent renewable energy for the future. This paper focuses on potential scenarios of EGS development in a locally and in regard to geothermal exploration, poorly known geological setting—the Variscan fold-and-thrust belt —for district heating and cooling of the Göttingen University campus. On average, the considered single EGS doublet might cover about 20% of the heat demand and 6% of the cooling demand of the campus. The levelized cost of heat (LCOH), net present value (NPV) and CO2 abatement cost were evaluated with the help of a spreadsheet-based model. As a result, the majority of scenarios of the reference case are currently not profitable. Based on the analysis, EGS heat output should be at least 11 MWth (with the brine flow rate being 40 l/s and wellhead temperature being 140 °C) for a potentially profitable project. These parameters can be a target for subsurface investigation, reservoir modeling and hydraulic stimulation at a later stage. However, sensitivity analysis presented some conditions that yield better results. Among the most influential parameters on the outcome are subsidies for research wells, proximity to the campus, temperature drawdown and drilling costs. If realized, the EGS project in Göttingen might save up to 18,100 t CO2 (34%) annually.
    Digitale ISSN: 2076-3263
    Thema: Geologie und Paläontologie
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  • 51
    Publikationsdatum: 2021-08-20
    Beschreibung: Transport infrastructure (TI) plays a crucial role in socioeconomic development. The increase of TI inequality, an all-pervading phenomenon in both developed and developing countries, has been an obstacle to sustainable economic growth. The relationship between TI inequality and economic growth has attracted considerable interest over the past three decades. However, the relationship remains obscure, and people find it impossible to utilize to develop economies. This study collected a panel of empirical data from 1982 to 2015 from China to calculate the Gini coefficient and conduct the Granger causality test. The data analysis results show that TI inequality is not always conducive to economic growth. A softening TI inequality helps address the issues of uneven economic growth across regions in the long term. The short-term effects of improving TI inequality at the national level are reflected in the network effect. In addition, the “social filters” facilitate the region to absorb the economic benefits brought by the improvement of TI inequality. These findings offer a way to address the increase of TI inequality and shed light on the ways to improve transport investment from the perspective of economic growth.
    Digitale ISSN: 2073-445X
    Thema: Land- und Forstwirtschaft, Gartenbau, Fischereiwirtschaft, Hauswirtschaft
    Standort Signatur Erwartet Verfügbarkeit
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  • 52
    Publikationsdatum: 2021-08-20
    Beschreibung: Black soldier fly (Hermetia illucens) larvae (BSFL) are a promising, sustainable source of nutrients, however, there is limited knowledge regarding the food safety of consuming BSFL. This study determined the safety of consuming BSFL for direct human consumption in terms of microbial, heavy metal and allergen content. Microbial counts were determined using ISO (International Organization for Standardization) methods, heavy metals were determined using inductively coupled plasma mass spectrometry and allergens were determined via Orbitrap mass spectrometry and ELISA (enzyme-linked immunosorbent assay) kits. Feed and killing method influenced the presence of Bacillus cereus (p = 0.011), and only the killing method influenced Escherichia coli (p 〈 0.00) and total viable count (TVC) (p 〈 0.00). Blanching resulted in a 3-log reduction in E. coli and a 3.4 log reduction in the TVC counts. Salmonella spp. and Listeria spp. were not detected in the BSFL samples. Heavy metals were detected although they were below maximum legal limits. Cross-reactive allergens, tropomyosin and arginine kinase, were detected in the BSFL samples, although the clinical significance requires research. The feed fed to the BSFL and blanching were found to influence the safety of consuming BSFL, highlighting the importance of incorporating sufficient decontamination steps, such as blanching, to ensure food safety.
    Digitale ISSN: 2304-8158
    Thema: Chemie und Pharmazie
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  • 53
    Publikationsdatum: 2021-08-20
    Beschreibung: Malaysia implemented its first Movement Control Order (MCO) during the early phase of the COVID-19 pandemic to slow the transmission of the virus. This study aimed to explore the public perception of the MCO implementation and people’s experiences during this period. The study employed qualitative explorative in-depth interviews conducted with 23 Malaysian adults from various demographic backgrounds. Thematic analysis was performed using NVivo 12. Three main themes were identified: a period of information surge, heterogeneous emotional response, and attempts to adapt. During the MCO, the participants obtained information from multiple platforms. They suggested the need for clear and repeated instructions to avoid confusion and misinformation. They also acknowledged the importance of the MCO in breaking the chain of transmission and safeguarding high-risk groups; however, they also expressed that stricter enforcement from the authorities was warranted. The changes in the participants’ work–life routines, lack of physical interaction, and uncertainty about their health and the economy due to the MCO negatively impacted their psychological states. Despite these challenges, the participants attempted to adapt to life under the MCO in different ways. The findings imply that during a crisis, the public tends to seek clear and reliable information, experience emotional turmoil, and adapt to changes. The MCO implementation can be improved through an effective communication strategy and efforts to battle misinformation.
    Print ISSN: 1661-7827
    Digitale ISSN: 1660-4601
    Thema: Energietechnik , Medizin
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  • 54
    Publikationsdatum: 2021-08-19
    Beschreibung: This case series study aimed to evaluate the safety, feasibility, and positive outcome of the neurorehabilitation multimodal protocol (NRMP) in 16 chronic post-surgical IVDD Hansen type I dogs, with OFS 0/DPP− (n = 9) and OFS 1/DPP+ (n = 7). All were enrolled in the NRMP for a maximum of 90 days and were clinically discharged after achieving ambulation. The NRMP was based on locomotor training, functional electrical stimulation, transcutaneous electrical spinal cord stimulation, and 4-aminopyridine (4-AP) pharmacological management. In the Deep Pain Perception (DPP)+ dogs, 100% recovered ambulation within a mean period of 47 days, reaching OFS ≥11, which suggests that a longer period of time is needed for recovery. At follow-up, all dogs presented a positive evolution with voluntary micturition. Of the DPP− dogs admitted, all achieved a flexion/extension locomotor pattern within 30 days, and after starting the 4-AP, two dogs were discharged at outcome day 45, with 78% obtaining Spinal Reflex Locomotion (SRL) and automatic micturition within a mean period of 62 days. At follow-up, all dogs maintained their neurological status. After the NRMP, ambulatory status was achieved in 88% (14/16) of dogs, without concurrent events. Thus, an NRMP may be an important therapeutic option to reduce the need for euthanasia in the clinical setting.
    Digitale ISSN: 2076-2615
    Thema: Biologie , Land- und Forstwirtschaft, Gartenbau, Fischereiwirtschaft, Hauswirtschaft
    Standort Signatur Erwartet Verfügbarkeit
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  • 55
    Publikationsdatum: 2021-08-19
    Beschreibung: Increasing the bearing capacity of reinforced concrete structures, reducing material consumption, and ensuring quality are critical in modern construction. The article presents an experimental study of the ultimate compressive strains of short fiber basalt reinforced concrete columns and provides recommendations for increasing the bearing capacity using steel reinforcement bars with greater strength. The columns were tested in an upright position using a hydraulic press. Strains were measured with dial indicators and a strain gauge station. It was shown that the addition of 10% coarse basalt fiber increased the ultimate compressibility of concrete on ordinary crushed stone by 19.8%, and expanded clay concrete by 26.1%, which led to the strain hardening of concrete under compression by 9.0% and 12%, respectively. Ultimate compressive strains in fiber-reinforced concrete short columns with combined reinforcement increased 1.42 times in columns on a lightweight aggregate and 1.19 times on heavy aggregate. An increase in the ultimate compressibility of concrete makes it possible to use steel reinforcement with greater strength in compressed elements as the concrete crushing during compression occurs primarily due to the reaching of critical values by tensile stresses in the transverse direction. This makes it possible to manufacture structures with a higher load-bearing capacity and less material consumption. A practical example of the application of the proposed approach is given.
    Digitale ISSN: 2076-3417
    Thema: Allgemeine Naturwissenschaft
    Standort Signatur Erwartet Verfügbarkeit
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  • 56
    Publikationsdatum: 2021-08-19
    Beschreibung: The threshing of frozen corn is accompanied by breakage and adherence, which influence the cleaning performance when the corn-cleaning mixture is separated and cleaned. In order to reduce the impurity ratio and loss ratio during frozen corn cleaning and provide theoretical support for frozen corn combine harvesting, this study employed a self-made air-screen cleaning system with adjustable parameters. The optimal process parameters of frozen corn cleaning were determined by using the response surface method (RSM). The influences of the fan speed (FS), vibrational frequency (VF), and screen opening (SO) on the cleaning performance were explored. The results showed that all three process parameters had significant effects on the impurity ratio (IR) and loss ratio (LR). The fan speed had the most significant impact. The cleaning performance was optimal when the fan speed was 102.7 rad/s, the vibration frequency was 6.42 Hz, and the screen opening was 21.9 mm, corresponding to a 0.80% impurity ratio and a 0.61% loss ratio. The predicted values of the regression models were consistent with the experimental results with a relative error of less than 5%. The reliability and accuracy of regression models were established and confirmed.
    Digitale ISSN: 2077-0472
    Thema: Land- und Forstwirtschaft, Gartenbau, Fischereiwirtschaft, Hauswirtschaft
    Standort Signatur Erwartet Verfügbarkeit
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  • 57
    Publikationsdatum: 2021-08-19
    Beschreibung: Prophylactic antibiotic usage during delivery is a common practice worldwide, especially in low- to middle-income countries. Guidelines have been published to reduce antibiotic overuse; however, data describing the use of prophylactic antibiotics and clinician adherence to guidelines in low- to middle-income countries remain limited. This study aimed to describe the prevalence of prophylactic antibiotic use, factors associated with its use, and clinician adherence to guidelines. A retrospective review was conducted for all deliveries from 1 January 2016 to 31 December 2018 at a tertiary level hospital in Indonesia. The prevalence of prophylactic antibiotic use during delivery was 47.1%. Maternal education level, Ob/Gyn specialist-led delivery, a history of multiple abortions, C-section, premature membrane rupture, and antepartum hemorrhage were independently associated with prophylactic antibiotic use. Clinician adherence to the guidelines was 68.9%. Adherence to guidelines was the lowest in conditions where the patient had only one indication for prophylactic antibiotics (aOR 0.36, 95% CI 0.24–0.54). The findings showed that the prevalence of prophylactic antibiotic use during delivery was moderate to high. Adherence to local guidelines was moderate. Updating the local prescribing guidelines may improve clinician adherence.
    Digitale ISSN: 2079-6382
    Thema: Chemie und Pharmazie , Medizin
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  • 58
    Publikationsdatum: 2021-08-19
    Beschreibung: Phenolic compounds have long been of great importance in the pharmaceutical, food, and cosmetic industries. Unfortunately, conventional extraction procedures have a high cost and are time consuming, and the solvents used can represent a safety risk for operators, consumers, and the environment. Deep eutectic solvents (DESs) are green alternatives for extraction processes, given their low or non-toxicity, biodegradability, and reusability. This review discusses the latest research (in the last two years) employing DESs for phenolic extraction, solvent components, extraction yields, extraction method characteristics, and reviewing the phenolic sources (natural products, by-products, wastes, etc.). This work also analyzes and discusses the most relevant DES-based studies for phenolic extraction from natural sources, their extraction strategies using DESs, their molecular mechanisms, and potential applications.
    Digitale ISSN: 1420-3049
    Thema: Chemie und Pharmazie
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  • 59
    Publikationsdatum: 2021-08-19
    Beschreibung: Fungi from the Candida genus are widespread commensals and, at the same time, are the leading cause of fungal infections worldwide. For instance, vulvovaginal candidiasis (VVC) affects approximately 75% of women at least once in their lifetime, remaining the second most common gynecological infection. On the contrary, hospital-acquired fungal bloodstream infections (BSIs), although less frequent, are characterized by a high mortality rate. Undoubtedly, the main reason for this situation are virulence factors that these yeast-like fungi can produce, and the ability to form a biofilm is one of the most important of them.. Due to the low effectiveness of classic antimycotics against Candida biofilms, an intense search for new drugs capable of eradicating this structure is highly demanded. One of the most promising groups of compounds exhibiting such properties are antimicrobial peptides (AMPs). This study focuses on a comparison of the efficacy of Omiganan and fluconazole alone and in combination against Candida strains isolated from BSIs. The obtained results are consistent with our previous reports on the effectiveness of Omiganan against clinical strains isolated from VVC. This is also the first report on the combinatory application of Omiganan in the context of fungal BSI. The majority of combinations with fluconazole showed an additive effect, as well as a synergistic effect in the range of certain concentrations. Importantly, such effects are visible at concentrations much lower than for those compounds used individually. Potentially, this entails the possibility of limiting the adverse effects (e.g., toxicity) of Omiganan and fluconazole applied in vivo, thus improving the safety profile of this particular antifungal therapy.
    Digitale ISSN: 2079-6382
    Thema: Chemie und Pharmazie , Medizin
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  • 60
    Publikationsdatum: 2021-08-19
    Beschreibung: This empirical study assesses the effect of CO2 emissions, urbanization, energy consumption, and agriculture on Thailand’s economic growth using a dataset between 1970 and 2018. The ARDL and the frequency domain causality (FDC) approaches were applied to assess these interconnections. The outcome of the bounds test suggested a long-term association among the variables of investigation. The ARDL outcomes reveal that urbanization, agriculture, energy consumption, and CO2 emissions positively trigger Thailand’s economic growth. Additionally, the frequency domain causality test was used to detect a causal connection between the series. The main benefit of this technique is that it can detect a causal connection between series at different frequencies. To the understanding of the authors, this is the first study in the case of Thailand that will apply the FDC approach to capture the causal linkage between GDP and the regressors. The outcomes of the causality test suggested that CO2 emissions, urbanization, energy consumption, and agriculture can predict Thailand’s economic growth in the long term. These outcomes have far-reaching implications for economic performance and Thailand’s macroeconomic indicators.
    Digitale ISSN: 1996-1073
    Thema: Energietechnik
    Standort Signatur Erwartet Verfügbarkeit
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  • 61
    Publikationsdatum: 2021-08-20
    Beschreibung: The muskrat is a neozoon species that has occupied many countries of continental North Europe after its introduction from north America as fur animals. Due to its burrowing activity it damages river and canal banks and structures of flood control. For this reason, the eradication of this alien species is recommended. Muskrats are also of parasitological interest since they can act as suitable intermediate hosts for Echinococcus multilocularis. On the other hand, little is known on the other helminths that infect muskrats. A total of 130 muskrats of different age groups trapped in different habitats in the Barnim district of the Brandenburg state by a professional hunter were examined for parasites and seven trematodes (Echinostoma sp., Notocotylus noyeri, Plagiorchis elegans, Plagiorchis arvicolae, Psilosostoma simillimum, P. spiculigerum, Opisthorchis felineus and four larval cestode species (Hydatigera taeniaeformis, Taenia martis, Taenia polyacantha, Taenia crassiceps) were detected. Larval stages of E. multilocularis were not found. O. felineus was found for the first time in muskrats in Germany. All the named parasites were present in Europe prior to the introduction of muskrats. With a prevalence of 48.9%, Strobilocercus fasciolaris, the larval stage of the cat tapeworm, H. taeniaeformis, was the most frequent parasite found in adult muskrats.
    Digitale ISSN: 2076-2615
    Thema: Biologie , Land- und Forstwirtschaft, Gartenbau, Fischereiwirtschaft, Hauswirtschaft
    Standort Signatur Erwartet Verfügbarkeit
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  • 62
    Publikationsdatum: 2021-08-20
    Beschreibung: C-type natriuretic peptide (CNP) is an important vascular regulator that is present in the brain. Our previous study demonstrated the innate neuroprotectant role of CNP in the neonatal brain after hypoxic-ischemic (HI) insults. In this study, we further explored the role of CNP in cerebrovascular pathology using both in vivo and in vitro models. In a neonatal mouse HI brain injury model, we found that intracerebroventricular administration of recombinant CNP dose-dependently reduces brain infarct size. CNP significantly decreases brain edema and immunoglobulin G (IgG) extravasation into the brain tissue, suggesting a vasculoprotective effect of CNP. Moreover, in primary brain microvascular endothelial cells (BMECs), CNP dose-dependently protects BMEC survival and monolayer integrity against oxygen-glucose deprivation (OGD). The vasculoprotective effect of CNP is mediated by its innate receptors NPR2 and NPR3, in that inhibition of either NPR2 or NPR3 counteracts the protective effect of CNP on IgG leakage after HI insult and BMEC survival under OGD. Of importance, CNP significantly ameliorates brain atrophy and improves neurological deficits after HI insults. Altogether, the present study indicates that recombinant CNP exerts vascular protection in neonatal HI brain injury via its innate receptors, suggesting a potential therapeutic target for the treatment of neonatal HI brain injury.
    Print ISSN: 1661-6596
    Digitale ISSN: 1422-0067
    Thema: Chemie und Pharmazie
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  • 63
    Publikationsdatum: 2021-08-20
    Beschreibung: The number of medically compromised dental patients is increasing every year with the increase in the super-aged population. Many of these patients have underlying psychiatric problems and diseases, which need to be recognized by dental professionals for better treatment outcomes. The aim of this narrative review article is to summarize the psychological and psychiatric backgrounds of medically compromised patients who are frequently visited and taken care of by dentists using findings from recent systematic reviews and meta-analyses. Anxiety and symptoms of depression, post-traumatic stress disorders, panic disorders, poor cognitive functions, and poor quality of life were some of the common psychological backgrounds in medically compromised patients. Additionally, the consequences of these psychological problems and the considerations that need to be taken by the dentist while treating these patients have been discussed. Dental professionals should be aware of and recognize the different psychological backgrounds of medically compromised dental patients in order to provide appropriate dental treatment and to prevent oral conditions from worsening.
    Print ISSN: 1661-7827
    Digitale ISSN: 1660-4601
    Thema: Energietechnik , Medizin
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  • 64
    Publikationsdatum: 2021-08-20
    Beschreibung: Water uptake is a seminal process in seed germination. Salt and polyethylene glycol (PEG) are known to retard seed germination rates and percentages, which is often attributed to osmotic effects. Here, we quantified water uptake in wheat seeds killed with a hot needle, finding evidence of three distinct water uptake pools. The fast pool was unaffected by salt, and likely represents cell walls and other apoplastic material. Water uptake into the medium and slow pools was slowed by salt addition, with the medium pool thought to be cellular, while the slow pool is presumably related to endosperm hydration. Salt caused a minor decrease in the water uptake rates and maximum seed water content, while PEG strongly suppressed both parameters. Seeds transferred between water and salt solutions followed the water uptake trajectories of the solution into which they were transferred. Seeds transferred from PEG to water achieved final seed water contents similar to water control seeds, while seeds transferred from water to PEG achieved significantly higher final water contents than PEG controls. This work confirms that salt and PEG have distinct effects on water uptake by wheat seeds.
    Digitale ISSN: 2073-4395
    Thema: Land- und Forstwirtschaft, Gartenbau, Fischereiwirtschaft, Hauswirtschaft , Wirtschaftswissenschaften
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  • 65
    Publikationsdatum: 2021-08-20
    Beschreibung: Power Factor Correction (PFC) single-phase AC/DC converters are used in several power electronics applications as full wave control rectifiers improving power quality and providing high standards of efficiency. Many papers dealing with the description or use of such topologies have been published in recent years; however, a review that describes and organizes their specific details has not been reported in the technical literature. Therefore, this paper presents an extensive review of PFC single-phase AC/DC converters operating with the Boost converter topology for low and medium voltage as well as and power appliances. A categorization of bridge, semi-bridgeless, and bridgeless, in accordance with the construction characteristics, was carried out in order to unify the technical terminology. Benefits and disadvantages are described and analyzed in detail. Furthermore, a comparison performance in terms of PFC, Total Harmonic Distortion (THD), power capacity, electromagnetic compatibility (EMC), number of elements, and efficiency is included.
    Digitale ISSN: 2076-3417
    Thema: Allgemeine Naturwissenschaft
    Standort Signatur Erwartet Verfügbarkeit
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  • 66
    Publikationsdatum: 2021-08-20
    Beschreibung: Evaluation and monitoring of wireless sensor networks (WSN) and the parameters defining their operations and design, such as energy consumption, latency, and stability, is a complex task due to interaction with real devices. For greater control of these variables, the use of simulators arises as an alternative. Cooja is a WSN simulator/emulator which handles the devices’ controllers and multiple communication protocol implementations, such as RPL (RPL is one of the most used protocol in IoT). However, Cooja does not consider either the implementation of an energy model (it has infinite energy consumption) nor the visual behavior of the topology construction, although these aspects are crucial for effective network analysis and decision taking. This paper presents the design and the implementation of ViTool-BC, a software built on top of Cooja, which allows the creation of different energy estimation models and also to visualize in real time the behavior of WSN topology construction. In addition, ViTool-BC offers a heat map of energy consumption traces. Therefore, this tool helps researchers to monitor in real time the topology construction, node disconnection, and battery depletion, aspects to be considered in the analysis of the available routing protocols in Cooja.
    Digitale ISSN: 2076-3417
    Thema: Allgemeine Naturwissenschaft
    Standort Signatur Erwartet Verfügbarkeit
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  • 67
    Publikationsdatum: 2021-08-20
    Beschreibung: Small nucleolar RNA (snoRNA) were one of our earliest recognised classes of non-coding RNA, but were largely ignored by cancer investigators due to an assumption that their activities were confined to the nucleolus. However, as full genome sequences have become available, many new snoRNA genes have been identified, and multiple studies have shown their functions to be diverse. The consensus now is that many snoRNA are dysregulated in cancers, are differentially expressed between cancer types, stages and metastases, and they can actively modify disease progression. In addition, the regulation of the snoRNA class is dominated by the cancer-supporting mTOR signalling pathway, and they may have particular significance to immune cell function and anti-tumour immune responses. Given the recent advent of therapeutics that can target RNA molecules, snoRNA have robust potential as drug targets, either solely or in the context of immunotherapies.
    Digitale ISSN: 2079-7737
    Thema: Biologie
    Standort Signatur Erwartet Verfügbarkeit
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  • 68
    Publikationsdatum: 2021-08-20
    Beschreibung: The south of Portugal is one of the regions that will be most affected by the impacts of climate change (CC), with an expected increase in water scarcity. Irrigated super-intensive olive orchards occupy a large area of the used agricultural surface in the Alentejo region, south of Portugal, making it necessary to adapt this crop to the effects of CC. This study assessed the impacts of CC and defined adaptation measures concerning irrigation management of the super-intensive olive orchard. To compute the crop irrigation requirement (CIR), the soil water balance model ISAREG was combined with climate data relative to the reference period 1971–2000 and to the representative concentration pathways RCP4.5 and RCP8.5 for the periods 2011–2040, 2041–2070, and 2071–2100. The growing degree-days (GDD) approach was used to estimate olive phenology for these CC scenarios. Unchanged irrigation management with an average CIR increase up to 16% in RCP4.5 and 31% in RCP8.5 is expected. By adopting higher levels of water deficit, water savings of up to 22% can be realized. The results showed that the anticipated CIR increase for the CC scenarios can be mitigated through regulated deficit irrigation strategies.
    Digitale ISSN: 2073-4395
    Thema: Land- und Forstwirtschaft, Gartenbau, Fischereiwirtschaft, Hauswirtschaft , Wirtschaftswissenschaften
    Standort Signatur Erwartet Verfügbarkeit
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  • 69
    Publikationsdatum: 2021-08-20
    Beschreibung: 5-aminolevulinic acid (ALA), a key precursor in the biosynthesis of porphyrins, can improve plant tolerance to various environmental stresses. However, it is unclear whether ALA can improve tolerance in poplar. Here, we investigated the effects of ALA on poplars under drought and salt stresses. ALA pretreatment exhibited less morphological damage, reduced leaf malonaldehyde content (MDA) and electrolyte leakage (EL), and increased leaf relative water content (RWC), proline (PRO), superoxide dismutase (SOD), and peroxidase (POD) content under stresses. Furthermore, exogenous ALA mitigated the decrease in photosynthetic capacity, and restored the chlorophyll content (Chl), net CO2 assimilation rate, stomatal conductance (Gs), transpiration rate (Tr), maximal photochemical quantum yield of PSII (Fv/Fm), actual quantum yield of photosynthesis (YII), and electron transfer rate (ETR) of poplar under various stresses. qRT-PCR showed that ALA up-regulated the expression of antiporters and aquaporins genes, which are associated with Na+ exclusion in the leaf cells and the transport activity of aquaporins. In summary, ALA pretreatment significantly improved the stress tolerance of poplar, decreasing the degree of membrane lipid peroxidation and promoting the photosynthesis and antioxidant capacity of leaves. In addition, our results showed that ALA might mediate Na+ transporter and aquaporins activity, thereby increasing the salt tolerance of poplar.
    Digitale ISSN: 1999-4907
    Thema: Land- und Forstwirtschaft, Gartenbau, Fischereiwirtschaft, Hauswirtschaft
    Standort Signatur Erwartet Verfügbarkeit
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  • 70
    Publikationsdatum: 2021-08-20
    Beschreibung: Background Patients admitted to intensive care units (ICU) are at an increased risk of developing immobility related complications. Physiotherapists are challenged to employ preventive and rehabilitative strategies to combat these effects. Passive limb range of motion (PROM) exercises- a part of early mobilization-aid in maintaining joint range of motion and functional muscle strength and forms a part of treatment for patients in ICU. However, there is a lack of evidence on practice of PROM exercises on patients admitted to ICU in the United Arab Emirates (UAE). This study aimed at exploring practices regarding the same in UAE. Methods This survey, conducted from January 2021 to February 2021 in College of Physiotherapy, Sharjah University studied practice of physiotherapists in the intensive care units. Physiotherapists currently working in ICU completed an online questionnaire composed of forty-two questions about physiotherapy service provision, assessment and intervention in the intensive care units. Results 33 physiotherapists completed the survey. 66.6% of respondents routinely assessed PROM for all the patients in ICU referred for physiotherapy. 84.8% of them assessed all the joints. More than half of the respondents (57.8%) reported that they administered PROM regularly to all the patients. According to 63.6% respondents, maintaining joint range of motion was the main reason for performing PROM. Responses pertaining to sets and repetitions of PROM were variable ranging from 1–6 sets and from 3 to 30 repetitions. Personal experience, resources/financial consideration and research findings were found to have influence on the practice. Conclusions PROM was found to be one of the frequently used mobilization techniques administered by physiotherapists in the intensive care units and was mostly performed after assessment. Maintaining joint range of motion was the main aim for performing PROM. Variability was found in the sets and repetitions of PROM administered. Various factors influenced the practice of PROM.
    Digitale ISSN: 1932-6203
    Thema: Medizin , Allgemeine Naturwissenschaft
    Publiziert von Public Library of Science
    Standort Signatur Erwartet Verfügbarkeit
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  • 71
    Publikationsdatum: 2021-08-20
    Beschreibung: The role the mammary epithelial circadian clock plays in gland development and lactation is unknown. We hypothesized that mammary epithelial clocks function to regulate mammogenesis and lactogenesis, and propose the core clock transcription factor BMAL1:CLOCK regulates genes that control mammary epithelial development and milk synthesis. Our objective was to identify transcriptional targets of BMAL1 in undifferentiated (UNDIFF) and lactogen differentiated (DIFF) mammary epithelial cells (HC11) using ChIP-seq. Ensembl gene IDs with the nearest transcriptional start site to ChIP-seq peaks were explored as potential targets, and represented 846 protein coding genes common to UNDIFF and DIFF cells and 2773 unique to DIFF samples. Genes with overlapping peaks between samples (1343) enriched cell-cell adhesion, membrane transporters and lipid metabolism categories. To functionally verify targets, an HC11 line with Bmal1 gene knocked out (BMAL1-KO) using CRISPR-CAS was created. BMAL1-KO cultures had lower cell densities over an eight-day growth curve, which was associated with increased (p
    Digitale ISSN: 1932-6203
    Thema: Medizin , Allgemeine Naturwissenschaft
    Publiziert von Public Library of Science
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  • 72
    Publikationsdatum: 2021-08-20
    Beschreibung: This paper presents the design of NaviPBx, an ultrasound-navigated prostate cancer biopsy system. NaviPBx is designed to support an affordable and sustainable national healthcare program in Senegal. It uses spatiotemporal navigation and multiparametric transrectal ultrasound to guide biopsies. NaviPBx integrates concepts and methods that have been independently validated previously in clinical feasibility studies and deploys them together in a practical prostate cancer biopsy system. NaviPBx is based entirely on free open-source software and will be shared as a free open-source program with no restriction on its use. NaviPBx is set to be deployed and sustained nationwide through the Senegalese Military Health Service. This paper reports on the results of the design process of NaviPBx. Our approach concentrates on “frugal technology”, intended to be affordable for low–middle income (LMIC) countries. Our project promises the wide-scale application of prostate biopsy and will foster time-efficient development and programmatic implementation of ultrasound-guided diagnostic and therapeutic interventions in Senegal and beyond.
    Digitale ISSN: 2313-433X
    Thema: Informatik
    Standort Signatur Erwartet Verfügbarkeit
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  • 73
    Publikationsdatum: 2021-08-20
    Beschreibung: Objectives N-benzoyl-DL-arginine peptidase (trypsin-like peptidase) is specifically produced by certain strains of periodontitis-associated bacteria. We aimed to examine the effectiveness of an objectively quantified trypsin-like peptidase activity assay (TLP-AA) for detecting severe periodontitis. Methods The study population included 347 adults (108 men and 239 women; average age, 43.3 years) who underwent a full-mouth periodontal examination. Specimens for the TLP-AA were obtained using tongue swabs. Using a color reader, the TLP-AA results were obtained as a* values, with higher positive a* values indicating an increased intense enzymatic activity. The predictive validity of the TLP-AA results for severe periodontitis was assessed using receiver operating characteristic curve analysis and the periodontitis case definition provided by the Centers for Disease Control and Prevention/American Academy of Periodontology as the gold standard. Furthermore, multivariable logistic regression analyses were performed to predict severe periodontitis using the TLP-AA results and health characteristics, as the exposure variables. Results Severe periodontitis was observed in 5.2% of the participants. TLP-AA had high diagnostic accuracy for severe periodontitis, with an area under the curve of 0.83 (95% confidence interval [CI]: 0.75–0.92). The cut-off score for the a* value that best differentiated individuals with severe periodontitis was 0.09, with a sensitivity of 83% and specificity of 77%. Multivariable logistic regression analyses revealed that the TLP-AA results were significantly associated with severe periodontitis after adjusting for health characteristics (adjusted odds ratios: 1.90 [95% CI: 1.37–2.62] for the a* value). Conclusions Objectively quantified TLP-AA results are potentially useful for detecting severe periodontitis in epidemiological surveillance.
    Digitale ISSN: 1932-6203
    Thema: Medizin , Allgemeine Naturwissenschaft
    Publiziert von Public Library of Science
    Standort Signatur Erwartet Verfügbarkeit
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  • 74
    Publikationsdatum: 2021-08-10
    Beschreibung: Ultradian glucocorticoid rhythms are highly conserved across mammalian species, however, their functional significance is not yet fully understood. Here we demonstrate that pulsatile corticosterone replacement in adrenalectomised rats induces a dynamic pattern of glucocorticoid receptor (GR) binding at ~3,000 genomic sites in liver at the pulse peak, subsequently not found during the pulse nadir. In contrast, constant corticosterone replacement induced prolonged binding at the majority of these sites. Additionally, each pattern further induced markedly different transcriptional responses. During pulsatile treatment, intragenic occupancy by active RNA polymerase II exhibited pulsatile dynamics with transient changes in enrichment, either decreased or increased depending on the gene, which mostly returned to baseline during the inter-pulse interval. In contrast, constant corticosterone exposure induced prolonged effects on RNA polymerase II occupancy at the majority of gene targets, thus acting as a sustained regulatory signal for both transactivation and repression of glucocorticoid target genes. The nett effect of these differences were consequently seen in the liver transcriptome as RNA-seq analysis indicated that despite the same overall amount of corticosterone infused, twice the number of transcripts were regulated by constant corticosterone infusion, when compared to pulsatile. Target genes that were found to be differentially regulated in a pattern-dependent manner were enriched in functional pathways including carbohydrate, cholesterol, glucose and fat metabolism as well as inflammation, suggesting a functional role for dysregulated glucocorticoid rhythms in the development of metabolic dysfunction.
    Print ISSN: 1553-7390
    Digitale ISSN: 1553-7404
    Thema: Biologie
    Publiziert von Public Library of Science
    Standort Signatur Erwartet Verfügbarkeit
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  • 75
    Publikationsdatum: 2021-08-20
    Beschreibung: Introduction Suicidality is a risk of a person committing suicide often characterized by suicidal ideation, intent or attempts. Despite the high burden of suicidality among individuals living with HIV and HAIDS, there is paucity of data on the impact of suicidality on clinical (such as CD4 counts and HIV disease progression) and behavioural outcomes (such as adherence to HIV Medications). Cross-sectional investigations of these associations are often complicated by bidirectional causal relationships and hence the need for longitudinal study designs. We conducted a cohort study to determine the impact of suicidality on clinical and behavioural outcomes among adults living with HIV/AIDS in Uganda. Materials and methods We conducted the study among 1099 ART naïve adults living with HIV/AIDS in Uganda. Data were collected at three time points: baseline, 6 and 12 months. Multiple regression and discrete time survival models were used to determine the relationship between suicidality and indices of HIV outcomes. Results Majority of the participants were female and the participant mean age was 35 years. Most of them (73%) had primary or no formal education. The proportion of participants with suicidality decreased from 2.9% at baseline to roughly 1% both at month 6 and month 12. Of the investigated clinical and behavioural outcomes, baseline suicidality only had a negative impact on missing a dose of ART where the odds of missing a dose of ART were 8.25 (95% CI 2.45–27.71, p〉0.01) times higher for participants with suicidality compared to those without suicidality. The following outcomes were not significantly impacted by baseline suicidality: HIV clinical stage, CD4 count and risky sexual behaviour. Conclusions The fact that baseline suicidality significantly negatively impacted ART adherence calls for the incorporation of psychosocial interventions to target indices of psychological distress such as suicidality to improve HIV related outcomes.
    Digitale ISSN: 1932-6203
    Thema: Medizin , Allgemeine Naturwissenschaft
    Publiziert von Public Library of Science
    Standort Signatur Erwartet Verfügbarkeit
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  • 76
    Publikationsdatum: 2021-08-19
    Beschreibung: High interstitial level of ATP and its lysate adenosine in the cancer microenvironment are considered a halo mark of cancer. Adenosine acts as a strong immune suppressor. However, the source of ATP release is unclear. We clarified the release of ATP via volume-regulated anion channels (VRACs) in breast cell lines using an ATP luminescence imaging system. We detected a slowly rising diffuse pattern of ATP release that was only observed in undifferentiated cells, not in differentiated primary cultured cells. This was confirmed by suppression with DCPIB, a blocker of VRACs, and shRNA for LRRC8A, an indispensable subunit of VRACs. We herein demonstrated that the inflammatory mediator sphingosine-1-phosphate (S1P), which exists abundantly in the cancer microenvironment, induced a diffuse pattern of ATP release isovolumetrically. The response was dose-dependent and suppressed by the knock-down of LRRC8A. It was also suppressed by blockers of S1P receptor 1 and 2 (W146 and JTE013, respectively). RTqPCR demonstrated the prominent presence of S1PR1 and S1PR2 mRNAs. We discussed the roles of S1P-induced ATP release in the cancer microenvironment.
    Digitale ISSN: 2075-1729
    Thema: Biologie
    Standort Signatur Erwartet Verfügbarkeit
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  • 77
    Publikationsdatum: 2021-08-20
    Beschreibung: Seaweeds are an important ingredient of functional foods recommended for daily food, due to their unique compositions and nutritional value. Padina tetrastromatica is a brown edible seaweed that is commonly found along the coastal regions of Peninsular Malaysia and consumed as food by some coastal communities. This study investigates the nutritional and antihyperglycaemic potential of P. tetrastromatica extracts, which is generally accepted as an important functional food. In our methodology, we induced diabetes intraperitoneally in experimental animals with a dose of 65 mg kg−1 body weight of streptozotocin. Oral treatment with 200 and 400 mg kg−1 of P. tetrastromatica ethanolic and ethyl acetate extracts were initiated, respectively, to experimental rats once daily for 18 days. Metformin was used as the positive control. Biochemical estimations and histopathological analysis were included in this study. Treatment with P. tetrastromatica extracts significantly lowered the plasma glucose levels in Streptozotocin-induced diabetic rats. In addition, P. tetrastromatica extract treatment also showed a significant reduction in serum alanine transaminase levels. However, no significant changes were observed in serum aspartate transaminase levels. The ethyl acetate extract of P. tetrastromatica at 400 mg kg−1 dose shows some nephroprotective effect, which is observed from the significant increase in the plasma albumin levels. Histopathological evaluation revealed no marked morphological changes in tissues of the isolated organs of the ethyl acetate extract-treated group, revealing the safe nature of P. tetrastromatica.
    Digitale ISSN: 2304-8158
    Thema: Chemie und Pharmazie
    Standort Signatur Erwartet Verfügbarkeit
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  • 78
    Publikationsdatum: 2021-08-20
    Beschreibung: The number of fatalities in the construction industry is highest among all industries; thus, various losses in the form of fatalities in construction represent a significant factor for safety management. If a fatality occurs, it is important to estimate the overall loss, as a significant financial loss occurs for each project participant. However, in studies of the cost of accidents involving a fatality conducted abroad, the framework cannot be applied as it is because insurance types, systems, and legal cost systems differ by country. Therefore, we developed a framework for calculating the fatality loss considering various aspects of labor, industry, and regulations in Korea. This was done in four steps: (i) data collection and criteria selection; (ii) proposed framework development; (iii) conduct of questionnaire surveys for the case study; and (iv) analysis and evaluation of the case study. As a result of the data analysis after the case study of general construction companies, the total fatality loss was estimated to be 2,198,260 USD/person. The contributions of this study are the development of a framework composed of newly discovered items that can acquire reliable data in consideration of the properties of the construction industry.
    Print ISSN: 1661-7827
    Digitale ISSN: 1660-4601
    Thema: Energietechnik , Medizin
    Standort Signatur Erwartet Verfügbarkeit
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  • 79
    Publikationsdatum: 2021-08-20
    Beschreibung: Traditional research methods in software defect prediction use part of the data in the same project to train the defect prediction model and predict the defect label of the remaining part of the data. However, in the practical realm of software development, the software project that needs to be predicted is generally a brand new software project, and there is not enough labeled data to build a defect prediction model; therefore, traditional methods are no longer applicable. Cross-project defect prediction uses the labeled data of the same type of project similar to the target project to build the defect prediction model, so as to solve the problem of data loss in traditional methods. However, the difference in data distribution between the same type of project and the target project reduces the performance of defect prediction. To solve this problem, this paper proposes a cross-project defect prediction method based on manifold feature transformation. This method transforms the original feature space of the project into a manifold space, then reduces the difference in data distribution of the transformed source project and the transformed target project in the manifold space, and finally uses the transformed source project to train a naive Bayes prediction model with better performance. A comparative experiment was carried out using the Relink dataset and the AEEEM dataset. The experimental results show that compared with the benchmark method and several cross-project defect prediction methods, the proposed method effectively reduces the difference in data distribution between the source project and the target project, and obtains a higher F1 value, which is an indicator commonly used to measure the performance of the two-class model.
    Digitale ISSN: 1999-5903
    Thema: Informatik
    Standort Signatur Erwartet Verfügbarkeit
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  • 80
    Publikationsdatum: 2021-08-12
    Beschreibung: In this study, the sequential extraction method was applied to extract selected potentially toxic elements (PTEs) (Cd, Cr, Cu, Fe, Ni, Pb and Zn) in river sediments collected from the Blood River situated in Seshego area, Limpopo Province, South Africa. The study aimed to assess a possible trend of mobilisation of these elements from sediment to water. The accuracy of the sequential extraction method was confirmed by analysing sediment-certified reference material, and quantitative percentage recoveries ranging from 86 to 119%, 81 to 111% and 77 to 119% were achieved for exchangeable, reducible and oxidisable fractions, respectively. The potential risk of the PTEs in sediments was evaluated. The calculated values of contamination factor (CF) as well as risk assessment code (RAC) for Cd, Cu, Ni and Pb revealed the mobility of these elements. The PTEs in river sediments are at a high toxicity-risk level and could therefore cause a threat to organisms dwelling in sediments and humans via consumption of crops irrigated with the polluted river water.
    Digitale ISSN: 2075-163X
    Thema: Geologie und Paläontologie
    Standort Signatur Erwartet Verfügbarkeit
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  • 81
    Publikationsdatum: 2021-08-20
    Beschreibung: This paper discusses the performance of the short pitch-based carbon fiber reinforced mortar (CFRM) composite considering its key properties and cost-effectiveness. Five different types of mortar composite were produced using 0–4% volume contents of short pitch-based carbon fibers. The mortar composites were tested for inverted slump cone flow (flow time and volume flow), unit weight, air content, compressive strength, flexural strength, impact resistance, and water absorption. The cost-effectiveness of CFRM was assessed based on the performance to cost ratio (PCR), which was calculated for each mortar composite, considering its workability, mechanical properties, and durability. The inverted slump cone volume flow was counted as a measure of workability, whereas the compressive strength, flexural strength, and impact resistance were considered as the major attributes of the mechanical behavior. In addition, the water absorption was used as a measure of durability. The test results revealed that the mortar composite made with 3% carbon fibers provided adequate workability, a relatively high unit weight and low air content, the highest compressive strength, excellent flexural strength, good impact resistance, and the lowest water absorption. It was also found that the PCR increased up to 3% carbon fibers. Beyond a 3% fiber content, the PCR significantly decreased. The overall research findings revealed that the mortar with 3% carbon fibers was the optimum and most cost-effective mortar composite.
    Digitale ISSN: 1996-1944
    Thema: Maschinenbau
    Standort Signatur Erwartet Verfügbarkeit
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  • 82
    Publikationsdatum: 2021-08-20
    Beschreibung: The large production of non-degradable petrol-based plastics has become a major global issue due to its environmental pollution. Biopolymers produced by microorganisms such as polyhydroxyalkanoates (PHAs) are gaining potential as a sustainable alternative, but the high cost associated with their industrial production has been a limiting factor. Post-transcriptional regulation is a key step to control gene expression in changing environments and has been reported to play a major role in numerous cellular processes. However, limited reports are available concerning the regulation of PHA accumulation in bacteria, and many essential regulatory factors still need to be identified. Here, we review studies where the synthesis of PHA has been reported to be regulated at the post-transcriptional level, and we analyze the RNA-mediated networks involved. Finally, we discuss the forthcoming research on riboregulation, synthetic, and metabolic engineering which could lead to improved strategies for PHAs synthesis in industrial production, thereby reducing the costs currently associated with this procedure.
    Digitale ISSN: 2075-1729
    Thema: Biologie
    Standort Signatur Erwartet Verfügbarkeit
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  • 83
    Publikationsdatum: 2021-08-19
    Beschreibung: Black garlic (BG) is a form of aged garlic obtained from raw garlic (Allium sativum) via Millard reaction under high temperature (60–90 °C) and humidity (70–90%) for a period of time. Several studies reported higher contents of water-soluble antioxidants compounds (S-allyl cysteine, S-allyl-mercapto cysteine), 5-hydroxymethylfurfural, organosulfur compounds, polyphenol, volatile compounds, and products of other Millard reactions compared to fresh garlic after the thermal processing. Recent studies have demonstrated that BG and its bioactive compounds possess a wide range of biological activities and pharmacological properties that preserve and show better efficacy in preventing different types of diseases. Most of these benefits can be attributed to its anti-oxidation, anti-inflammation, anti-obesity, hepatoprotection, hypolipidemia, anti-cancer, anti-allergy, immunomodulation, nephroprotection, cardiovascular protection, and neuroprotection. Substantial studies have been conducted on BG and its components against different common human diseases in the last few decades. Still, a lot of research is ongoing to find out the therapeutic effects of BG. Thus, in this review, we summarized the pre-clinical and clinical studies of BG and its bioactive compounds on human health along with diverse bioactivity, a related mode of action, and also future challenges.
    Digitale ISSN: 1420-3049
    Thema: Chemie und Pharmazie
    Standort Signatur Erwartet Verfügbarkeit
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  • 84
    Publikationsdatum: 2021-08-20
    Beschreibung: Objective. The main objective of this study was to investigate the relationship between poverty, religion, and suicidal thoughts among U.S. youth. The disparities regarding gender, race, and ethnicity with regard to suicidal thoughts were also assessed. Methods. A cross-sectional correlational research design was used for this study and a national representative sample of 1945 young adults aged 18 to 25 was selected from the 2014 National Survey on Drug Use and Health. Logistic regression analysis with interaction effects was utilized to determine if poverty and religion were associated with suicidal thoughts. Results. About 43 percent of the sample reported having suicidal thoughts when things got worse and this prevalence rate varied by gender and race/ethnicity with white males self-disclosing the highest rate of suicidal thoughts. After adjusting for demographic and socioeconomic characteristics, black males who lived up to two times the poverty line had a higher likelihood of suicidal thoughts (p = 0.011), and religion protected against suicidal thoughts (p = 0.012). Youth with lower education and poor health were more inclined to have suicidal thoughts than their peers. Conclusions. Suicide is the second leading cause of death for American young adults aged 18 to 25. Understanding these differences between social determinants of suicide can help public health researchers strategize how to make evidence-based recommendations for suicide prevention efforts.
    Print ISSN: 1661-7827
    Digitale ISSN: 1660-4601
    Thema: Energietechnik , Medizin
    Standort Signatur Erwartet Verfügbarkeit
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  • 85
    Publikationsdatum: 2021-08-20
    Beschreibung: In mammalian cells, two cellular organelles, mitochondria and peroxisomes, share the ability to degrade fatty acid chains. Although each organelle harbors its own fatty acid β-oxidation pathway, a distinct mitochondrial system feeds the oxidative phosphorylation pathway for ATP synthesis. At the same time, the peroxisomal β-oxidation pathway participates in cellular thermogenesis. A scientific milestone in 1965 helped discover the hepatomegaly effect in rat liver by clofibrate, subsequently identified as a peroxisome proliferator in rodents and an activator of the peroxisomal fatty acid β-oxidation pathway. These peroxisome proliferators were later identified as activating ligands of Peroxisome Proliferator-Activated Receptor α (PPARα), cloned in 1990. The ligand-activated heterodimer PPARα/RXRα recognizes a DNA sequence, called PPRE (Peroxisome Proliferator Response Element), corresponding to two half-consensus hexanucleotide motifs, AGGTCA, separated by one nucleotide. Accordingly, the assembled complex containing PPRE/PPARα/RXRα/ligands/Coregulators controls the expression of the genes involved in liver peroxisomal fatty acid β-oxidation. This review mobilizes a considerable number of findings that discuss miscellaneous axes, covering the detailed expression pattern of PPARα in species and tissues, the lessons from several PPARα KO mouse models and the modulation of PPARα function by dietary micronutrients.
    Print ISSN: 1661-6596
    Digitale ISSN: 1422-0067
    Thema: Chemie und Pharmazie
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  • 86
    Publikationsdatum: 2021-08-20
    Beschreibung: Background The COVID-19 vaccination campaign in the US has been immensely successful in vaccinating those who are receptive, further increases in vaccination rates however will require more innovative approaches to reach those who remain hesitant. Developing vaccination strategies that are modelled on what people want could further increase uptake. Methods and findings To inform COVID-19 vaccine distribution strategies that are aligned with public preferences we conducted a discrete choice experiment among the US public (N = 2,895) between March 15 to March 22, 2021. We applied sampling weights, evaluated mean preferences using mixed logit models, and identified latent class preference subgroups. On average, the public prioritized ease, preferring single to two dose vaccinations (mean preference: -0.29; 95%CI: -0.37 to -0.20), vaccinating once rather than annually (mean preference: -0.79; 95%CI: -0.89 to -0.70) and reducing waiting times at vaccination sites. Vaccine enforcement reduced overall vaccine acceptance (mean preference -0.20; 95%CI: -0.30 to -0.10), with a trend of increasing resistance to enforcement with increasing vaccine hesitancy. Latent class analysis identified four distinct preference phenotypes: the first prioritized inherent “vaccine features” (46.1%), the second were concerned about vaccine “service delivery” (8.8%), a third group desired “social proof” of vaccine safety and were susceptible to enforcement (13.2%), and the fourth group were “indifferent” to vaccine and service delivery features and resisted enforcement (31.9%). Conclusions This study identifies several critical insights for the COVID-19 public health response. First, identifying preference segments is essential to ensure that vaccination services meet the needs of diverse population subgroups. Second, making vaccination easy and promoting autonomy by simplifying services and offering the public choices (where feasible) may increase uptake in those who remain deliberative. And, third vaccine mandates have the potential to increase vaccination rates in susceptible groups but may simultaneously promote control aversion and resistance in those who are most hesitant.
    Digitale ISSN: 1932-6203
    Thema: Medizin , Allgemeine Naturwissenschaft
    Publiziert von Public Library of Science
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  • 87
    Publikationsdatum: 2021-08-20
    Print ISSN: 0028-0836
    Digitale ISSN: 1476-4687
    Thema: Biologie , Chemie und Pharmazie , Medizin , Allgemeine Naturwissenschaft , Physik
    Publiziert von Springer Nature
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  • 88
    Publikationsdatum: 2021-08-20
    Beschreibung: Introduction The single-leg heel raise test (SLHR) is commonly used in clinical settings to approximate plantar flexor strength, yet this is neither validated nor supported physiologically. The purposes of this study were to: determine (1) associations between SLHR repetitions, maximal plantar flexor strength, and reductions in strength; and (2) whether sex differences exist in performance of the SLHR. Methods Twenty-eight young, healthy participants (14 males,14 females, 19–30 years) performed repeated single-leg heel raises to task failure. Pre- and post-task measures included maximal voluntary isometric contractions (MVIC), and voluntary activation and contractile properties of the plantar flexor muscles, assessed using peripheral electrical stimulation of the tibial nerve. Surface electromyography was recorded for the medial and lateral gastrocnemius, soleus, and anterior tibialis muscles. Results The SLHR resulted in 20.5% reductions in MVIC torque (p
    Digitale ISSN: 1932-6203
    Thema: Medizin , Allgemeine Naturwissenschaft
    Publiziert von Public Library of Science
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  • 89
    Publikationsdatum: 2021-08-20
    Beschreibung: Stream temperature science and management is rapidly shifting from single-metric driven approaches to multi-metric, thermal regime characterizations of streamscapes. Given considerable investments in recovery of cold-water fisheries (e.g., Pacific salmon and other declining native species), understanding where cold water is likely to persist, and how cold-water thermal regimes vary, is critical for conservation. California’s unique position at the southern end of cold-water ecosystems in the northern hemisphere, variable geography and hydrology, and extensive flow regulation requires a systematic approach to thermal regime classification. We used publicly available, long-term (〉 8 years) stream temperature data from 77 sites across California to model their thermal regimes, calculate three temperature metrics, and use the metrics to classify each regime with an agglomerative nesting algorithm. Then, we assessed the variation in each class and considered underlying physical or anthropogenic factors that could explain differences between classes. Finally, we considered how different classes might fit existing criteria for cool- or cold-water thermal regimes, and how those differences complicate efforts to manage stream temperature through regulation. Our results demonstrate that cool- and cold-water thermal regimes vary spatially across California. Several salient findings emerge from this study. Groundwater-dominated streams are a ubiquitous, but as yet, poorly explored class of thermal regimes. Further, flow regulation below dams imposes serial discontinuities, including artificial thermal regimes on downstream ecosystems. Finally, and contrary to what is often assumed, California reservoirs do not contain sufficient cold-water storage to replicate desirable, reach-scale thermal regimes. While barriers to cold-water conservation are considerable and the trajectory of cold-water species towards extinction is dire, protecting reaches that demonstrate resilience to climate warming remains worthwhile.
    Digitale ISSN: 1932-6203
    Thema: Medizin , Allgemeine Naturwissenschaft
    Publiziert von Public Library of Science
    Standort Signatur Erwartet Verfügbarkeit
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  • 90
    Publikationsdatum: 2021-08-20
    Beschreibung: Euphorbia species have a rich history of ethnomedicinal use and ethnopharmacological applications in drug discovery. This is due to the presence of a wide range of diterpenes exhibiting great structural diversity and pharmacological activities. As a result, Euphorbia diterpenes have remained the focus of drug discovery investigations from natural products. The current review documents over 350 diterpenes, isolated from Euphorbia species, their structures, classification, biosynthetic pathways, and their structure–activity relationships for the period covering 2013–2020. Among the isolated diterpenes, over 20 skeletal structures were identified. Lathyrane, jatrophane, ingenane, ingenol, and ingol were identified as the major diterpenes in most Euphorbia species. Most of the isolated diterpenes were evaluated for their cytotoxicity activities, multidrug resistance abilities, and inhibitory activities in vitro, and reported good activities with significant half-inhibitory concentration (IC50) values ranging from 10–50 µM. The lathyranes, isopimaranes, and jatrophanes diterpenes were further found to show potent inhibition of P-glycoprotein, which is known to confer drug resistance abilities in cells leading to decreased cytotoxic effects. Structure–activity relationship (SAR) studies revealed the significance of a free hydroxyl group at position C-3 in enhancing the anticancer and anti-inflammatory activities and the negative effect it has in position C-2. Esterification of this functionality, in selected diterpenes, was found to enhance these activities. Thus, Euphorbia diterpenes offer a valuable source of lead compounds that could be investigated further as potential candidates for drug discovery.
    Digitale ISSN: 1420-3049
    Thema: Chemie und Pharmazie
    Standort Signatur Erwartet Verfügbarkeit
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  • 91
    Publikationsdatum: 2021-08-19
    Beschreibung: Rotifers are the most diverse group in freshwater zooplankton and play an important role in food webs and ecosystems. DNA barcoding has become a useful approach to investigate species diversity at local and regional scales, but its application is still limited by efficient primers for the group. To test a pair of primers 30F/885R recently designed for rotifers, we applied them to investigating regional species diversity in the freshwater of South China. We sequenced the cytochrome c oxidase subunit I (COI) gene of rotifers collected from the investigated 23 reservoirs in a large river basin and obtained 145 COI sequences from 33 species in 14 genera. The mean PCR success rate for all tested species was 50%. The 145 sequenced mtCOI in this study covered 33 of 64 identified morphological taxa, including most of the common species in the basin. The intraspecific genetic distance was calculated with a K2P model for 24 rotifer species occurring in the quantitative samples, in which 15 rotifers, such as Keratella cochlearis and Brachionus calyciflorus, had a genetic distance higher than 5%. The high intraspecific genetic differentiation indicates that cryptic species are probably common in (sub)tropical China.
    Digitale ISSN: 1424-2818
    Thema: Biologie
    Standort Signatur Erwartet Verfügbarkeit
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  • 92
    Publikationsdatum: 2021-08-20
    Beschreibung: This paper investigated the appropriate specifications of Engel curves for non-food expenditure categories and estimated the deprivation indices of non-food needs in rural areas using a semi parametric examination of the presence of saturation points. The study used the extended partial linear model (EPLM) and adopted two estimation methods—the double residual estimator and differencing estimator—to obtain flexible shapes across different expenditure categories and estimate equivalence scales. We drew on data of the Egyptian Household Income, Expenditure, and Consumption Survey (HIEC). Our paper provides empirical evidence that the rankings of most non-food expenditure categories is of rank three at most. Rural households showed high economies of scale in non-food consumption, with child’s needs accounting for only 10% of adult’s non-food needs. Based on semi-parametrically estimated consumption behavior, the tendency of non-food expenditure categories to saturate did not emerge. While based on parametrically estimated consumption behavior, rural areas exhibited higher deprivation indices in terms of health and education expenditure categories, which indicates the need to design specific programs economically targeting such vulnerable households.
    Digitale ISSN: 1932-6203
    Thema: Medizin , Allgemeine Naturwissenschaft
    Publiziert von Public Library of Science
    Standort Signatur Erwartet Verfügbarkeit
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  • 93
    Publikationsdatum: 2021-08-20
    Beschreibung: Menzerath’s law is a quantitative linguistic law which states that, on average, the longer is a linguistic construct, the shorter are its constituents. In contrast, Menzerath-Altmann’s law (MAL) is a precise mathematical power-law-exponential formula which expresses the expected length of the linguistic construct conditioned on the number of its constituents. In this paper, we investigate the anatomy of MAL for constructs being word tokens and constituents being syllables, measuring its length in graphemes. First, we derive the exact form of MAL for texts generated by the memoryless source with three emitted symbols, which can be interpreted as a monkey typing model or a null model. We show that this null model complies with Menzerath’s law, revealing that Menzerath’s law itself can hardly be a criterion of complexity in communication. This observation does not apply to the more precise Menzerath-Altmann’s law, which predicts an inverted regime for sufficiently range constructs, i.e., the longer is a word, the longer are its syllables. To support this claim, we analyze MAL on data from 21 languages, consisting of texts from the Standardized Project Gutenberg. We show the presence of the inverted regime, not exhibited by the null model, and we demonstrate robustness of our results. We also report the complicated distribution of syllable sizes with respect to their position in the word, which might be related with the emerging MAL. Altogether, our results indicate that Menzerath’s law—in terms of correlations—is a spurious observation, while complex patterns and efficiency dynamics should be rather attributed to specific forms of Menzerath-Altmann’s law.
    Digitale ISSN: 1932-6203
    Thema: Medizin , Allgemeine Naturwissenschaft
    Publiziert von Public Library of Science
    Standort Signatur Erwartet Verfügbarkeit
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  • 94
    Publikationsdatum: 2021-08-20
    Beschreibung: The COVID-19 pandemic, caused by the SARS-CoV-2 virus, has had a significant impact on people’s daily lives. The rapidly spreading B.1.617 lineage harbors two key mutations—L452R and E484Q—in the receptor binding domain (RBD) of its spike (S) protein. To understand the impact and structural dynamics of the variations in the interface of S protein and its host factor, the human angiotensin-converting enzyme 2 (hACE2), triplicate 500 ns molecular dynamics simulations were performed using single (E484Q or L452R) and double (E484Q + L452R) mutant structures and compared to wild type simulations. Our results indicate that the E484Q mutation disrupts the conserved salt bridge formed between Lys31 of hACE2 and Glu484 of S protein. Additionally, E484Q, which could favor the up conformation of the RBD, may help in enhanced hACE2 binding and immune escape. L452R introduces a charged patch near the binding surface that permits increased electrostatic attraction between the proteins. An improved network of intramolecular interactions observed is likely to increase the stability of the S protein and conformational changes may prevent the binding of neutralizing antibodies. The results obtained from the molecular dynamics simulations suggest that structural and dynamic changes introduced by these variations enhance the affinity of the viral S protein to hACE2 and could form the basis for further studies.
    Digitale ISSN: 2218-273X
    Thema: Biologie
    Standort Signatur Erwartet Verfügbarkeit
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  • 95
    Publikationsdatum: 2021-08-20
    Beschreibung: In modern society, it is impossible to imagine life without polymeric materials. However, managing the waste composed of these materials is one of the most significant environmental issues confronting us in the present day. Recycling polymeric waste is the most important action currently available to reduce environmental impacts worldwide and is one of the most dynamic areas in industry today. Utilizing this waste could not only benefit the environment but also promote sustainable development and circular economy management. In its program statement, the European Union has committed to support the use of sorted polymeric waste. This study reviews recent attempts to recycle this waste and convert it by alternative technologies into fine, nano-, and microscale fibers using electrospinning, blowing, melt, or centrifugal spinning. This review provides information regarding applying reprocessed fine fibers in various areas and a concrete approach to mitigate the threat of pollution caused by polymeric materials.
    Digitale ISSN: 1996-1944
    Thema: Maschinenbau
    Standort Signatur Erwartet Verfügbarkeit
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  • 96
    Publikationsdatum: 2021-08-20
    Beschreibung: The present study aims to compare the levels of micro-RNA-146a and micro-RNA-126 in oral subgingival plaque and coronary plaque from artery walls in patients with coronary artery disease who suffer from generalized periodontitis. A total of 75 participants were selected and grouped into three categories of 25 patients each: GP+CAD, GP, and HP groups. GP+CAD consisted of patients diagnosed with generalized periodontitis (GP) and coronary artery disease (CAD). The GP+CAD group was further divided into two groups—GP+CADa: where subgingival plaque samples were collected; GP+CADb group: where coronary plaque samples were collected while the patient underwent a coronary artery bypass grafting surgery. The GP group consisted of 25 patients diagnosed with only generalized periodontitis. The HP group consisted of 25 systemically and periodontally healthy controls. miRNA-146a and miRNA126 levels were assessed in subgingival plaque (SP) samples from all groups. Results revealed that miRNA-146a was expressed at higher levels and miRNA-126 was downregulated in the GP+CAD group. microRNAs in subgingival plaque samples showed a significant correlation with the coronary plaque samples in the GP+CAD group. miRNA-146a and miRNA-126 were present in coronary artery disease patients with periodontitis. These micro-RNAs may serve as risk biomarkers for coronary artery disease and generalized periodontitis.
    Digitale ISSN: 1996-1944
    Thema: Maschinenbau
    Standort Signatur Erwartet Verfügbarkeit
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  • 97
    Publikationsdatum: 2021-08-20
    Beschreibung: For α∈[0,1], let Aα(Gσ)=αD(G)+(1−α)A(Gσ), where G is a simple undirected graph, D(G) is the diagonal matrix of its vertex degrees and A(Gσ) is the adjacency matrix of the signed graph Gσ whose underlying graph is G. In this paper, basic properties of Aα(Gσ) are obtained, its positive semidefiniteness is studied and some bounds on its eigenvalues are derived—in particular, lower and upper bounds on its largest eigenvalue are obtained.
    Digitale ISSN: 2227-7390
    Thema: Mathematik
    Standort Signatur Erwartet Verfügbarkeit
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  • 98
    Publikationsdatum: 2021-08-19
    Beschreibung: Electronic e-waste (e-waste) is a growing problem worldwide. In 2019, total global production reached 53.6 million tons, and is estimated to increase to 74.7 million tons by 2030. This rapid increase is largely fuelled by higher consumption rates of electrical and electronic goods, shorter life cycles and fewer repair options. E-waste is classed as a hazardous substance, and if not collected and recycled properly, can have adverse environmental impacts. The recoverable material in e-waste represents significant economic value, with the total value of e-waste generated in 2019 estimated to be US $57 billion. Despite the inherent value of this waste, only 17.4% of e-waste was recycled globally in 2019, which highlights the need to establish proper recycling processes at a regional level. This review provides an overview of global e-waste production and current technologies for recycling e-waste and recovery of valuable material such as glass, plastic and metals. The paper also discusses the barriers and enablers influencing e-waste recycling with a specific focus on Oceania.
    Digitale ISSN: 2075-4701
    Thema: Maschinenbau
    Standort Signatur Erwartet Verfügbarkeit
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  • 99
    Publikationsdatum: 2021-08-20
    Beschreibung: Temperate grassland soils store significant amounts of carbon (C). Estimating how much livestock grazing and manuring can influence grassland soil organic carbon (SOC) is key to improve greenhouse gas grassland budgets. The Rothamsted Carbon (RothC) model, although originally developed and parameterized to model the turnover of organic C in arable topsoil, has been widely used, with varied success, to estimate SOC changes in grassland under different climates, soils, and management conditions. In this paper, we hypothesise that RothC-based SOC predictions in managed grasslands under temperate moist climatic conditions can be improved by incorporating small modifications to the model based on existing field data from diverse experimental locations in Europe. For this, we described and evaluated changes at the level of: (1) the soil water function of RothC, (2) entry pools accounting for the degradability of the exogenous organic matter (EOM) applied (e.g., ruminant excreta), (3) the month-on-month change in the quality of C inputs coming from plant residues (i.e above-, below-ground plant residue and rhizodeposits), and (4) the livestock trampling effect (i.e., poaching damage) as a common problem in areas with higher annual precipitation. In order to evaluate the potential utility of these changes, we performed a simple sensitivity analysis and tested the model predictions against averaged data from four grassland experiments in Europe. Our evaluation showed that the default model’s performance was 78% and whereas some of the modifications seemed to improve RothC SOC predictions (model performance of 95% and 86% for soil water function and plant residues, respectively), others did not lead to any/or almost any improvement (model performance of 80 and 46% for the change in the C input quality and livestock trampling, respectively). We concluded that, whereas adding more complexity to the RothC model by adding the livestock trampling would actually not improve the model, adding the modified soil water function and plant residue components, and at a lesser extent residues quality, could improve predictability of the RothC in managed grasslands under temperate moist climatic conditions.
    Digitale ISSN: 1932-6203
    Thema: Medizin , Allgemeine Naturwissenschaft
    Publiziert von Public Library of Science
    Standort Signatur Erwartet Verfügbarkeit
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  • 100
    Publikationsdatum: 2021-08-20
    Beschreibung: Heavy metal is released from many industries into water. Before the industrial wastewater is discharged, the contamination level should be reduced to meet the recommended level as prescribed by the local laws of a country. They may be poisonous or cancerous in origin. Their presence does not only damage people, but also animals and vegetation because of their mobility, toxicity, and non-biodegradability into aquatic ecosystems. The review comprehensively discusses the progress made by various adsorbents such as natural materials, synthetic, agricultural, biopolymers, and commercial for extraction of the metal ions such as Ni2+, Cu2+, Pb2+, Cd2+, As2+ and Zn2+ along with their adsorption mechanisms. The adsorption isotherm indicates the relation between the amount adsorbed by the adsorbent and the concentration. The Freundlich isotherm explains the effective physical adsorption of the solute particle from the solution on the adsorbent and Langmuir isotherm gives an idea about the effect of various factors on the adsorption process. The adsorption kinetics data provide valuable insights into the reaction pathways, the mechanism of the sorption reaction, and solute uptake. The pseudo-first-order and pseudo-second-order models were applied to describe the sorption kinetics. The presented information can be used for the development of bio-based water treatment strategies.
    Digitale ISSN: 1996-1944
    Thema: Maschinenbau
    Standort Signatur Erwartet Verfügbarkeit
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