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  • Female  (132)
  • Structure-Activity Relationship  (22)
  • *Biological Evolution
  • American Association for the Advancement of Science (AAAS)  (157)
  • 1980-1984  (157)
  • 1980  (157)
Collection
Keywords
Publisher
  • American Association for the Advancement of Science (AAAS)  (157)
Years
  • 1980-1984  (157)
Year
  • 101
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    Clomid administration in rats (1980)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1980-02-29
    Description: 〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Malinak, L R -- Kaufman, R H -- Spjut, H J -- New York, N.Y. -- Science. 1980 Feb 29;207(4434):1008.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/7352297" target="_blank"〉PubMed〈/a〉
    Keywords: Animals ; Clomiphene/*pharmacology ; Female ; Metaplasia/chemically induced ; Pregnancy ; Pregnancy, Animal/*drug effects ; Rats ; Uterus/*drug effects/pathology
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
    Published by American Association for the Advancement of Science (AAAS)
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  • 102
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    Osteoporosis: new help for thinning bones (1980)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1980-02-08
    Description: 〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Marx, J L -- New York, N.Y. -- Science. 1980 Feb 8;207(4431):628-30.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/7352275" target="_blank"〉PubMed〈/a〉
    Keywords: Aging ; Bone Resorption ; Calcitonin/therapeutic use ; Calcium/*metabolism ; Dihydroxycholecalciferols/therapeutic use ; Estrogens/therapeutic use ; Female ; Humans ; Male ; Menopause ; Osteoporosis/drug therapy/*physiopathology/prevention & control ; Parathyroid Hormone/physiology
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
    Published by American Association for the Advancement of Science (AAAS)
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  • 103
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    Beta-lipotropin: a new aldosterone-stimulating factor (1980)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1980-07-11
    Description: Beta-Lipotropin stimulated the production of aldosterone in collagenase-dispersed rat adrenal capsular cells. The maximum response obtained with beta-lipotropin was the same as the response obtained with corticotropin and was greater than that obtained with angiotensin II. These data suggest that beta-lipotropin may play a role in aldosterone regulation.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Matsuoka, H -- Mulrow, P J -- Li, C H -- New York, N.Y. -- Science. 1980 Jul 11;209(4453):307-8.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/6247763" target="_blank"〉PubMed〈/a〉
    Keywords: Adrenal Glands/drug effects/*metabolism ; Adrenocorticotropic Hormone/pharmacology ; Aldosterone/*biosynthesis ; Animals ; Corticosterone/*biosynthesis ; Dose-Response Relationship, Drug ; Female ; Rats ; Sheep ; Swine ; beta-Lipotropin/*pharmacology
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
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  • 104
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    Puberty delay by a urinary cue from female house mice in feral populations (1980)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1980-08-15
    Description: Urine produced by wild female house mice, living in high- and low-density populations and confined to areas within a highway cloverleaf, was tested for its ability to delay puberty in juvenile female mice. Only urine collected from females in the dense population at its maximum density delayed puberty in test females. Urine collected when the population was less dense, or from a population that remained sparse, failed to delay puberty. These results suggest that a urinary factor present at high densities may delay puberty and thus help to slow further population growth.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Massey, A -- Vandenbergh, J G -- New York, N.Y. -- Science. 1980 Aug 15;209(4458):821-2.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/7190728" target="_blank"〉PubMed〈/a〉
    Keywords: Animals ; Animals, Wild/physiology ; Crowding ; Estrus ; Female ; Mice/*physiology/urine ; Pheromones/*urine ; *Population Density ; Pregnancy ; *Sexual Maturation
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
    Published by American Association for the Advancement of Science (AAAS)
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  • 105
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    Effect of interferon-alpha 1 from E. coli on some cell functions (1980)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1980-09-19
    Description: Interferon-alpha 1 from Escherichia coli transformed with a hybrid plasmid containing a human leukocyte complementary DNA insert, induces resistance to virus in appropriate target cells. It also shares the following properties with natural leukocyte interferon (IFN). (i) It enhances natural killing activity of human lymphocytes, (ii) it enhances antibody-dependent cell-mediated cytotoxicity, (iii) it suppresses antigen- and mitogen-induced leukocyte migration inhibition, (iv) it inhibits growth of IFN-sensitive Burkitt lymphoma cells. Since these activities are exhibited by a cloned protein species, they are due to IFN itself and not to other human proteins.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Masucci, M G -- Szigeti, R -- Klein, E -- Klein, G -- Gruest, J -- Montagnier, L -- Taira, H -- Hall, A -- Nagata, S -- Weissmann, C -- New York, N.Y. -- Science. 1980 Sep 19;209(4463):1431-5.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/6158096" target="_blank"〉PubMed〈/a〉
    Keywords: Antibody-Dependent Cell Cytotoxicity/drug effects ; Cell Division/drug effects ; Cell Migration Inhibition ; Cloning, Molecular ; *DNA, Recombinant ; Escherichia coli ; Humans ; Hypersensitivity, Delayed/immunology ; Immunity, Cellular/drug effects ; Interferons/genetics/*pharmacology ; Structure-Activity Relationship
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
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  • 106
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    At least three human type alpha interferons: structure of alpha 2 (1980)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1980-09-19
    Description: The sequence of a human leukocyte-derived complementary DNA (cDNA), Hif-2h, which directs the formation in Escherichia coli of a polypeptide, IFN-alpha 1, with interferon (IFN) activity has been described. A second IFN cDNA, Hif-SN206, which also elicits synthesis of a biologically active IFN, IFN-alpha 2, is described in this article. Whereas IFN-alpha 2 is twice as active on human as on bovine cells, IFN-alpha 1 is 10 to 20 times more active on bovine than on human cells. As deduced from the cDNA's, the messenger RNA's for the two IFN's differ in length and in 20 percent of the nucleotides; the mature IFN polypeptides differ in 17 percent of the amino acids. Both IFN-alpha 1 and IFN-alpha 2 differ from the lymphoblastoid IFN described by others. Therefore, at least three different IFN-alpha genes are expressed in man; studies on genomic DNA reveal the presence of at least eight IFN-related genes.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Streuli, M -- Nagata, S -- Weissmann, C -- New York, N.Y. -- Science. 1980 Sep 19;209(4463):1343-7.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/6158094" target="_blank"〉PubMed〈/a〉
    Keywords: Amino Acid Sequence ; Animals ; Base Sequence ; DNA, Recombinant ; Escherichia coli/genetics ; Genes ; Humans ; *Interferons/genetics ; Leukocytes ; Lymphocytes ; Mice ; RNA, Messenger/genetics ; Structure-Activity Relationship
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
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  • 107
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    DNA methylation and gene function (1980)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1980-11-07
    Description: In most higher organisms, DNA is modified after synthesis by the enzymatic conversion of many cytosine residues to 5-methylcytosine. For several years, control of gene activity by DNA methylation has been recognized as a logically attractive possibility, but experimental support has proved elusive. However, there is now reason to believe, from recent studies, that DNA methylation is a key element in the hierarchy of control mechanisms that govern vertebrate gene function and differentiation.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Razin, A -- Riggs, A D -- GM20483/GM/NIGMS NIH HHS/ -- GM25825/GM/NIGMS NIH HHS/ -- New York, N.Y. -- Science. 1980 Nov 7;210(4470):604-10.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/6254144" target="_blank"〉PubMed〈/a〉
    Keywords: Animals ; Cell Differentiation ; DNA/*physiology ; DNA (Cytosine-5-)-Methyltransferase/*metabolism ; DNA Restriction Enzymes/metabolism ; Deoxycytosine Nucleotides/*metabolism ; Deoxyribonucleoproteins/metabolism ; Gene Expression Regulation ; Methylation ; Methyltransferases/*metabolism ; Nucleosomes/ultrastructure ; Protein Binding ; Structure-Activity Relationship ; Substrate Specificity ; Tissue Distribution
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
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  • 108
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    Associative learning in premature hydranencephalic and normal twins (1980)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1980-11-28
    Description: A hydranencephalic infant lacking cerebral hemispheres and a normal twin were tested for associative learning. After repeated trials in which two stimuli were temporally paired, test trials were given in which the second stimulus was omitted. Cardiac orienting responses to stimulus omission indicated that learning had taken place in both infants.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Tuber, D S -- Berntson, G G -- Bachman, D S -- Allen, J N -- New York, N.Y. -- Science. 1980 Nov 28;210(4473):1035-7.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/7192015" target="_blank"〉PubMed〈/a〉
    Keywords: Anencephaly/*physiopathology ; Association/*physiology ; Behavior/physiology ; Brain/physiology ; Brain Stem/physiology ; Female ; Heart Rate ; Humans ; Hydranencephaly/*physiopathology ; Infant ; Infant, Newborn ; Infant, Premature/*psychology ; Male ; Pregnancy ; Twins, Dizygotic
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
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  • 109
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    Cigarette smoking associated with sleep difficulty (1980)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1980-02-01
    Description: A group of 50 smokers experienced greater sleep difficulty than a group of 50 nonsmokers matched by age and sex. The two groups did not differ in personality patterns or drug consumption. Also, sleep patterns significantly improved in a group of eight chronic smokers when they abstained from cigarette smoking. These findings are consistent with reports on the stimulant effects of nicotine.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Soldatos, C R -- Kales, J D -- Scharf, M B -- Bixler, E O -- Kales, A -- New York, N.Y. -- Science. 1980 Feb 1;207(4430):551-3.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/7352268" target="_blank"〉PubMed〈/a〉
    Keywords: Adult ; Coffee/adverse effects ; Female ; Humans ; Male ; Sleep Stages ; Sleep Wake Disorders/*etiology ; Smoking/*complications ; Substance Withdrawal Syndrome/physiopathology
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
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  • 110
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    Deficient natural killer cell activity in x-linked lymphoproliferative syndrome (1980)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1980-10-31
    Description: The activity of natural killer cells was found to be deficient in 10 of 12 males with X-linked lymphoproliferative syndrome, a life-threatening proliferation of lymphocytes after infection by Epstein-Barr virus. The activity levels of natural killer cells from affected males were increased after treatment with interferon in vitro, but normal levels of killing were not obtained. Deficient activity of killer cells in individuals with immunodeficiency and chronic infection by Epstein-Barr virus may contribute to the development of lymphoproliferative disorders.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Sullivan, J L -- Byron, K S -- Brewster, F E -- Purtilo, D T -- CA 23561-01/CA/NCI NIH HHS/ -- New York, N.Y. -- Science. 1980 Oct 31;210(4469):543-5.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/6158759" target="_blank"〉PubMed〈/a〉
    Keywords: Adolescent ; Adult ; Child ; Child, Preschool ; Cytotoxicity, Immunologic ; Female ; Humans ; *Immunity, Innate ; Immunologic Deficiency Syndromes/*genetics ; Infectious Mononucleosis/immunology ; Interferons/pharmacology ; Killer Cells, Natural/*immunology ; Lymphoproliferative Disorders/genetics/*immunology ; Male ; X Chromosome
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
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  • 111
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    Experimental induction of puberty in the infantile female rhesus monkey (1980)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1980-03-21
    Description: Normal ovulatory menstrual cycles were initiated in prepubertal female rhesus monkeys by the infusion of gonadotropin-releasing hormone for 6 minutes once every hou;. When this regimen was discontinued, the animals promptly reverted to an immature state. These findings permit the conclusion that neither adenohypophysial nor ovarian competence is limiting in the initiation of puberty and suggest that this process depends on the maturation of the neuroendocrine control system that directs the pulsatile secretion of gonadotropin-releasing hormone from the hypothalamus.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Wildt, L -- Marshall, G -- Knobil, E -- New York, N.Y. -- Science. 1980 Mar 21;207(4437):1373-5.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/6986658" target="_blank"〉PubMed〈/a〉
    Keywords: Animals ; Estradiol/blood ; Female ; Follicle Stimulating Hormone/blood ; Gonadotropin-Releasing Hormone/*pharmacology ; Hypothalamus/physiology ; Luteinizing Hormone/blood ; Macaca/*physiology ; Macaca mulatta/*physiology ; Menstruation/*drug effects ; Ovary/physiology ; Ovulation/*drug effects ; Pituitary Gland/physiology ; Progesterone/blood ; Sexual Maturation/*drug effects
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
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  • 112
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    Sexual characteristics of adult female mice are correlated with their blood testosterone levels during prenatal development (1980)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1980-05-09
    Description: Mice produce litters containing many pups, and the female fetuses that develop between male fetuses have significantly higher concentrations of the male sex steroid testosterone in both their blood and amniotic fluid than do females that develop between other female fetuses. These two types of females differ during later life in many sexually related characteristics. Thus, individual variation in sexual characteristics of adult female mice may be traceable to differential exposure to testosterone during prenatal development because of intrauterine proximity to male fetuses.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉vom Saal, F S -- Bronson, F H -- New York, N.Y. -- Science. 1980 May 9;208(4444):597-9.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/7367881" target="_blank"〉PubMed〈/a〉
    Keywords: Age Factors ; Amniotic Fluid/*metabolism ; Animals ; Estradiol/blood ; Estrus ; Female ; Fetal Blood/*metabolism ; Male ; Mice/*embryology ; Pregnancy ; Progesterone/blood ; *Sex Differentiation ; Sex Ratio ; Sexual Behavior, Animal/*physiology ; Testosterone/*blood
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
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  • 113
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    Maternal stress alters plasma testosterone in fetal males (1980)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1980-01-18
    Description: Titers of testosterone in plasma were determined by radioimmunoassay in male rat fetuses of stressed and control mothers on days 17, 18, 19, 21, and 23 (the day of birth) after conception. In fetuses of stressed mothers, testosterone concentrations were highest on day 17, declined on days 18 and 19, and then remained unchanged. In the control fetuses, testosterone increased from relatively low concentrations on day 17 to the highest amounts on days 18 and 19, and then declined. Thus, the persistence of feminine and impaired masculine sexual behavior in male offspring of stressed mothers could be due to the absence of a surge of circulating testosterone during days 18 and 19 after conception, a period postulated to be critical in the development of the central nervous system in the rat.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Ward, I L -- Weisz, J -- New York, N.Y. -- Science. 1980 Jan 18;207(4428):328-9.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/7188648" target="_blank"〉PubMed〈/a〉
    Keywords: Animals ; Disorders of Sex Development/embryology ; Female ; Fetal Blood/*analysis ; Gestational Age ; Humans ; Male ; Pregnancy ; Rats ; *Sex Differentiation ; Stress, Psychological/blood/*physiopathology ; Testosterone/*blood
    Print ISSN: 0036-8075
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    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
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  • 114
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    Behavioral responses to artificial food colors (1980)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1980-03-28
    Description: Twenty-two young children, maintained on a diet that excluded certain foods, were challenged intermittently with a blend of seven artificial colors in a double-blind trial. Parents' observations provided the criteria of response. One child that responded mildly to the challenge and one that responded dramatically were detected. The latter, a 34-month-old female, showed a significant increase in aversive behaviors. These results further confirm previous controlled studies.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Weiss, B -- Williams, J H -- Margen, S -- Abrams, B -- Caan, B -- Citron, L J -- Cox, C -- McKibben, J -- Ogar, D -- Schultz, S -- New York, N.Y. -- Science. 1980 Mar 28;207(4438):1487-9.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/7361103" target="_blank"〉PubMed〈/a〉
    Keywords: Behavior/*drug effects ; Child ; Child, Preschool ; Double-Blind Method ; Female ; Food Coloring Agents/adverse effects/*pharmacology ; Humans ; Hyperkinesis/etiology ; Male
    Print ISSN: 0036-8075
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  • 115
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    Asymmetry in facial expression (1980)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1980-08-15
    Description: 〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Sackeim, H A -- Gur, R C -- New York, N.Y. -- Science. 1980 Aug 15;209(4458):834-6.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/7403854" target="_blank"〉PubMed〈/a〉
    Keywords: Emotions ; *Facial Expression ; Female ; *Functional Laterality ; Humans ; Male ; Photography
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    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
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  • 116
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    Access of urinary nonvolatiles to the mammalian vomeronasal organ (1980)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1980-02-15
    Description: Guinea pigs were allowed to investigate urine that contained rhodamine, a nonvolatile fluorescent dye. Guinea pigs given free access to dyed urine exhibited fluorescence in their vomeronasal and septal organs but not on their olfactory epithelium. Fluorescence was not seen when unadulterated urine was presented. Thus compounds of low volatility, which do not reach the olfactory epithelium, may stimulate the vomeronasal system and provide information that is normally not provided by gustation or olfaction.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Wysocki, C J -- Wellington, J L -- Beauchamp, G K -- New York, N.Y. -- Science. 1980 Feb 15;207(4432):781-3.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/7352288" target="_blank"〉PubMed〈/a〉
    Keywords: Animals ; Female ; Fluorescent Dyes ; Functional Laterality ; Male ; Nasal Septum/physiology ; *Pheromones ; Sexual Behavior, Animal/physiology ; Smell/*physiology ; Urine/*physiology
    Print ISSN: 0036-8075
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  • 117
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    Auditory brainstem anomalies in human albinos (1980)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1980-09-12
    Description: Brainstem auditory evoked potentials recorded from human albinos indicate significant hemispheric asymmetry. The asymmetry is symptomatic of differences between decussated and nondecussated auditory pathways in albino and pigmented humans at approximately the level of the superior olivary nuclei. Abnormal decussation of auditory pathways in albinos probably coincides with known visual system anomalies.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Creel, D -- Garber, S R -- King, R A -- Witkop, C J Jr -- New York, N.Y. -- Science. 1980 Sep 12;209(4462):1253-5.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/7403883" target="_blank"〉PubMed〈/a〉
    Keywords: Adult ; Albinism/*physiopathology ; Auditory Pathways/*physiopathology ; Brain Stem/*physiopathology ; Evoked Potentials ; Female ; Functional Laterality ; Humans ; Male ; Olivary Nucleus/physiopathology
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  • 118
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    War gases as olfactory probes (1980)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1980-10-01
    Description: The tear gas ethyl bromoacetate is a fruity-smelling alkylating agent that blocks the ability of the frog nose to respond to esters and a variety of other odorants, but leaves sensitivity to amines unimpaired. Lachrymators and chemical warfare agents of other functional types such as sulfides (mustard gas) and amines (nitrogen mustards) may have similarly specific actions that will enable their use as chemical probes of the sense of smell.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Criswell, D W -- McClure, F L -- Schaefer, R -- Brower, K R -- New York, N.Y. -- Science. 1980 Oct;210(4468):425-6.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/6968976" target="_blank"〉PubMed〈/a〉
    Keywords: Alkylating Agents/*pharmacology ; Amines ; Animals ; Chemical Warfare Agents/*pharmacology ; Esters ; Membrane Potentials/drug effects ; Rana pipiens ; Smell/*drug effects/physiology ; Structure-Activity Relationship
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    Fertilization of squirrel monkey and hamster ova in the rabbit oviduct (xenogenous fertilization) (1980)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1980-06-27
    Description: Homologous sperm and ova of either squirrel monkeys or hamsters were placed in the oviducts of pseudopregnant rabbits. Xenogenous fertilization rates of 36 and 60 percent were obtained for squirrel monkey and hamster gametes, respectively.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉DeMayo, F J -- Mizoguchi, H -- Dukelow, W R -- New York, N.Y. -- Science. 1980 Jun 27;208(4451):1468-9.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/6770463" target="_blank"〉PubMed〈/a〉
    Keywords: Animals ; Cricetinae ; Female ; *Fertilization ; Haplorhini ; Oviducts/*physiology ; Ovum/*transplantation ; Saimiri ; Transplantation, Heterologous
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    Of human bonding: newborns prefer their mothers' voices (1980)
    American Association for the Advancement of Science (AAAS)
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    Publication Date: 1980-06-06
    Description: By sucking on a nonnutritive nipple in different ways, a newborn human could produce either its mother's voice or the voice of another female. Infants learned how to produce the mother's voice and produced it more often than the other voice. The neonate's preference for the maternal voice suggests that the period shortly after birth may be important for initiating infant bonding to the mother.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉DeCasper, A J -- Fifer, W P -- New York, N.Y. -- Science. 1980 Jun 6;208(4448):1174-6.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/7375928" target="_blank"〉PubMed〈/a〉
    Keywords: Auditory Perception/*physiology ; Discrimination (Psychology)/physiology ; Female ; Humans ; *Infant, Newborn ; Male ; *Mother-Child Relations ; Sucking Behavior/*physiology
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    Cerebral regional oxygen consumption and supply in anesthetized cat (1980)
    American Association for the Advancement of Science (AAAS)
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    Publication Date: 1980-07-25
    Description: The study involved quantitative measurement of arterial and venous oxygen saturation, oxygen extraction, blood flow, and oxygen consumption in specific areas of the brain. No regional differences in oxygen consumption were found in anesthetized cat brain, and the amount of oxygen available to all regions studied was more than 2.5 times the consumption throughout the brain.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Buckweitz, E -- Sinha, A K -- Weiss, H R -- New York, N.Y. -- Science. 1980 Jul 25;209(4455):499-501.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/7394515" target="_blank"〉PubMed〈/a〉
    Keywords: Anesthesia, General ; Animals ; Brain/blood supply/drug effects/*metabolism ; Cats ; Chloralose/*pharmacology ; Female ; Male ; Oxygen/*blood ; Oxygen Consumption/*drug effects ; Regional Blood Flow ; Tissue Distribution
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    Suppression of prolactin secretion in normal young women by 2-hydroxyestrone (1980)
    American Association for the Advancement of Science (AAAS)
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    Publication Date: 1980-10-03
    Description: The nonuterotropic natural estrogen 2-hydroxyestrone administered to normal young women results in a prompt and profound suppression of serum prolactin in most of the subjects. With the exception of dopamine, this is the only endogenous material known to strongly inhibit prolactin secretion, and its action suggests that the physiological regulation of prolactin by estrogens in the human is dual in nature, consisting of stimulation by estradiol and inhibition by its catechol estrogen metabolite.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Fishman, J -- Tulchinsky, D -- CA 22795/CA/NCI NIH HHS/ -- New York, N.Y. -- Science. 1980 Oct 3;210(4465):73-4.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/7414322" target="_blank"〉PubMed〈/a〉
    Keywords: Adult ; Drug Administration Schedule ; Estrogens/physiology ; Estrone/*analogs & derivatives ; Female ; Humans ; Hydroxyestrones/*pharmacology ; Prolactin/blood/*secretion ; Time Factors
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    Behavioral and physiological evidence of sexual climax in the female stump-tailed macaque (Macaca arctoides) (1980)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1980-06-27
    Description: Intense tonic/clonic uterine contractions and sudden increases in heart rate coincided with the behavioral homolog of a male ejaculatory response (minus seminal emission) in a normal female stump-tailed macaque engaged in homosexual mounting episodes. The behavioral patterns were also observed in four of ten females during 5 to 40 percent of heterosexual copulations. These observations demonstrate the existence of an orgasmic response in a nonhuman primate.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Goldfoot, D A -- Westerborg-van Loon, H -- Groeneveld, W -- Slob, A K -- New York, N.Y. -- Science. 1980 Jun 27;208(4451):1477-9.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/7384791" target="_blank"〉PubMed〈/a〉
    Keywords: Animals ; Female ; Macaca ; *Orgasm ; *Sexual Behavior, Animal ; Uterine Contraction
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    Successful culture of rat embryos on human serum: use in the detection of teratogens (1980)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1980-03-28
    Description: Growth of head-fold-stage rat embryos cultured with human serum for 48 hours was enhanced by supplementation with glucose. Embryo growth (protein and DNA contents) varied with the source of the serum. Serum from 16 of 19 untreated subjects produced normal embryos. Serum from five subjects undergoing cancer chemotherapy and six subjects receiving anticonvulsants was either lethal or teratogenic.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Chatot, C L -- Klein, N W -- Piatek, J -- Pierro, L J -- New York, N.Y. -- Science. 1980 Mar 28;207(4438):1471-3.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/7361097" target="_blank"〉PubMed〈/a〉
    Keywords: Adult ; Animals ; Anticonvulsants/pharmacology ; Antineoplastic Agents/pharmacology ; Blood ; Culture Media ; *Culture Techniques ; Drug Evaluation, Preclinical/*methods ; *Embryo, Mammalian/drug effects ; Female ; Glucose ; Humans ; Male ; Rats ; *Teratogens
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    Calmodulin plays a pivotal role in cellular regulation (1980)
    American Association for the Advancement of Science (AAAS)
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    Publication Date: 1980-01-04
    Description: The role of calcium ions (Ca2+) in cell function is beginning to be unraveled at the molecular level as a result of recent research on calcium-binding proteins and particularly on calmodulin. These proteins interact reversibly with Ca2+ to form a protein . Ca2+ complex, whose activity is regulated by the cellular flux of Ca2+. Many of the effects of Ca2+ appear to be exerted through calmodulin-regulated enzymes.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Cheung, W Y -- New York, N.Y. -- Science. 1980 Jan 4;207(4426):19-27.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/6243188" target="_blank"〉PubMed〈/a〉
    Keywords: 3',5'-Cyclic-AMP Phosphodiesterases/metabolism ; Allosteric Regulation ; Amino Acid Sequence ; Animals ; Biological Evolution ; Calcium/*physiology ; Calcium-Binding Proteins/*physiology ; Calmodulin/*physiology ; Cell Communication ; Cyclic AMP/*physiology ; Enzyme Activation ; Phospholipases A/metabolism ; Protein Kinases/*metabolism ; Receptors, Drug/physiology ; Structure-Activity Relationship ; Troponin/physiology
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    Alcoholic rhabdomyolysis: an experimental model in the rat (1980)
    American Association for the Advancement of Science (AAAS)
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    Publication Date: 1980-04-25
    Description: The main features of alcoholic rhabdomyolysis-skeletal muscle necrosis, marked elevation of serum creatine phosphokinase, and myoglobinuria-were produced in rats by a combination of relatively prolonged (2 to 4 weeks) exposure to ethanol and a brief period of food deprivation. This observation suggests that fasting may similarly trigger muscle injury during binge drinking in man. The effect of fasting is in part related to an increase in blood alcohol due to reduced alcohol clearance and in part caused by a fasting-induced potentiation of the toxic effects of high concentrations of alcohol of skeletal muscle.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Haller, R G -- Drachman, D B -- New York, N.Y. -- Science. 1980 Apr 25;208(4442):412-5.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/7189294" target="_blank"〉PubMed〈/a〉
    Keywords: Alcoholism/*complications ; Animals ; Creatine Kinase/blood ; *Disease Models, Animal ; Female ; *Food Deprivation ; Humans ; Muscular Diseases/blood/complications/*etiology/pathology ; Myoglobinuria/etiology ; Phosphates/blood ; Potassium/blood ; Rats ; Sodium/blood
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    Preferred sites of strand scission in DNA modified by andi-diol epoxide of benzo[a]pyrene (1980)
    American Association for the Advancement of Science (AAAS)
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    Publication Date: 1980-08-22
    Description: 〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Haseltine, W A -- Lo, K M -- D'Andrea, A D -- New York, N.Y. -- Science. 1980 Aug 22;209(4459):929-31.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/7403858" target="_blank"〉PubMed〈/a〉
    Keywords: Base Sequence ; Benzopyrenes/*pharmacology ; Carcinogens ; *DNA, Bacterial ; Dose-Response Relationship, Drug ; Epoxy Compounds ; Hydrolysis ; Lac Operon ; Mutagens ; Stereoisomerism ; Structure-Activity Relationship
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    Pentobarbital: stereospecific actions of (+) and (-) isomers revealed on cultured mammalian neurons (1980)
    American Association for the Advancement of Science (AAAS)
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    Publication Date: 1980-01-11
    Description: Stereoisomers of the barbiturate anesthetic pentobarbital were applied to mouse spinal neurons growing in tissue culture. Intracellular recordings of neuronal membrane properties revealed that the (+) and (-) isomers caused direct changes in membrane potential and conductance on some but not all of the cells tested. The action of the (+) isomer was predominantly excitatory, whereas the (-) isomer produced predominantly inhibitory responses. The (-) isomer was considerably more effective in potentiating inhibitory responses to the transmitter gamma-aminobutyric acid. The results show that pentobarbital has multiple effects on neuronal excitability and demonstrate the presence of stereospecific sites of barbiturate action on central neurons.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Huang, L Y -- Barker, J L -- New York, N.Y. -- Science. 1980 Jan 11;207(4427):195-7.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/7350656" target="_blank"〉PubMed〈/a〉
    Keywords: Action Potentials/drug effects ; Animals ; Cells, Cultured ; Dose-Response Relationship, Drug ; Electric Conductivity ; Membrane Potentials/drug effects ; Mice ; Neural Inhibition/drug effects ; Neurons/*drug effects ; Pentobarbital/*pharmacology ; Spinal Cord/embryology ; Stereoisomerism ; Structure-Activity Relationship
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    Monozygotic twin formation in mouse embryos in vitro (1980)
    American Association for the Advancement of Science (AAAS)
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    Publication Date: 1980-08-01
    Description: Monozygotic twins developed from cultured murine blastocysts at the ratio of approximately 1:100. The locus at which the denuded blastocysts attached to the culture dish was usually a random section of their mural trophoblasts, in which case single egg cylinders developed unilaterally. However, in those few blastocysts attaching with their antipolar mural trophoblasts, the inner cell mass became subdivided into two parts because of restrictions imposed on its growth by the apically situated polar trophoblasts and the plastic substrate. Each subdivision apparently incorporated totipotent cells, resulting in the bilateral formation of two egg cylinders sharing the same ectoplacental cone.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Hsu, Y C -- Gonda, M A -- New York, N.Y. -- Science. 1980 Aug 1;209(4456):605-6.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/7190325" target="_blank"〉PubMed〈/a〉
    Keywords: Animals ; Blastocyst/physiology ; Culture Media ; Embryo, Mammalian/*physiology ; Female ; Fertilization in Vitro ; Mice ; Pregnancy ; *Twins ; *Twins, Monozygotic
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    Prenatal exposure to diazepam alters behavioral development in rats (1980)
    American Association for the Advancement of Science (AAAS)
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    Publication Date: 1980-01-11
    Description: Characteristic potentiation of rat locomotion responses and acoustic startle reflexes that normally appear in the third postnatal week was absent in rats exposed to diazepam during the third week of gestation. Loss of these behaviors suggests a long-term effect that may result from changes in cellular development. Tissue undergoing neuronal differentation may be especially sensitive to drugs that act on the central nervous system, and the period in which differentiation occurs is perhaps critical for the induction of changes that are later expressed as altered behavior.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Kellogg, C -- Tervo, D -- Ison, J -- Parisi, T -- Miller, R K -- New York, N.Y. -- Science. 1980 Jan 11;207(4427):205-7.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/7350658" target="_blank"〉PubMed〈/a〉
    Keywords: Animals ; Auditory Perception/drug effects ; Behavior, Animal/*drug effects ; Diazepam/*pharmacology ; Female ; Fetus/*drug effects ; Gestational Age ; Motor Activity/drug effects ; Pregnancy ; Rats ; Reflex, Startle/drug effects ; Sound
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    Silent nucleotide substitutions and the molecular evolutionary clock (1980)
    American Association for the Advancement of Science (AAAS)
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    Publication Date: 1980-11-28
    Description: Half of the nucleotide substitutions during the evolutionary divergence of genes in animals, bacteria, and viruses are silent changes. These result from an inherent biochemical property of DNA and are fixed by genetic drift. Evolution may be viewed as a device for protecting DNA molecules from extinction.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Jukes, T H -- New York, N.Y. -- Science. 1980 Nov 28;210(4473):973-8.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/7434017" target="_blank"〉PubMed〈/a〉
    Keywords: Animals ; Base Sequence ; *Biological Evolution ; Codon ; DNA/*genetics ; DNA, Viral/genetics ; *Genes ; Genetic Code ; Globins/genetics ; Histones/genetics ; Mutation ; RNA, Messenger/genetics
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    Dexamethasone fails to suppress beta-endorphin plasma concentrations in humans and rhesus monkeys (1980)
    American Association for the Advancement of Science (AAAS)
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    Publication Date: 1980-08-15
    Description: In humans and rhesus monkeys, dexamethasone decreased concentrations of plasma cortisol but did not alter circulating beta-endorphin immunoreactivity. Contrary to current theory suggesting that pituitary beta-endorphin and adrenocorticotropic hormone are controlled by identical regulatory mechanisms for synthesis and release, our evidence suggests that in higher primates the established glucocorticoid feedback mechanism for the adrenocorticotropic hormone-cortisol system does not regulate beta-endorphin secretion in the same way.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Kalin, N H -- Risch, S C -- Cohen, R M -- Insel, T -- Murphy, D L -- New York, N.Y. -- Science. 1980 Aug 15;209(4458):827-8.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/6250217" target="_blank"〉PubMed〈/a〉
    Keywords: Adrenocorticotropic Hormone/secretion ; Adult ; Animals ; Dexamethasone/*pharmacology ; Endorphins/*blood/secretion ; Feedback ; Female ; Haplorhini ; Humans ; Hydrocortisone/blood ; Macaca mulatta ; Male ; Pituitary Gland, Anterior/secretion ; Protein Precursors/metabolism ; Species Specificity ; Stress, Physiological/blood
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    Math and sex: are girls born with less ability? (1980)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1980-12-12
    Description: 〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Kolata, G B -- New York, N.Y. -- Science. 1980 Dec 12;210(4475):1234-5.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/7434024" target="_blank"〉PubMed〈/a〉
    Keywords: Environment ; Female ; Humans ; Intelligence ; Male ; *Mathematics ; *Sex Factors
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    Control of the rhesus monkey menstrual cycle: permissive role of hypothalamic gonadotropin-releasing hormone (1980)
    American Association for the Advancement of Science (AAAS)
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    Publication Date: 1980-03-21
    Description: In rhesus monkeys with hypothalamic lesions (which appear to abolish the endogenous production of gonadotropin-releasing hormone), normal ovulatory mestrual cycles were reestablished by an unvarying, long-term replacement regimen consisting of one intravenous pulse of synthetic gonadotropic-releasing hormone per hour. This finding is in accord with the hypothesis that the pattern of pituitary gonadotropin secretion throughout the menstrual cycle (basal secretion interrupted, once every 28 days on the average, by a preovulatory surge) is not directed by alterations in hypothalamic gonadotropin-releasing hormone secretion but by the ebb and flow of ovarian estrogens acting directly on the pituitary gland.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Knobil, E -- Plant, T M -- Wildt, L -- Belchetz, P E -- Marshall, G -- New York, N.Y. -- Science. 1980 Mar 21;207(4437):1371-3.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/6766566" target="_blank"〉PubMed〈/a〉
    Keywords: Animals ; Castration ; Estradiol/pharmacology ; Female ; Gonadotropin-Releasing Hormone/*physiology ; Haplorhini ; Hypothalamus/*physiology ; Macaca/*physiology ; Macaca mulatta/*physiology ; *Menstruation/drug effects ; Pituitary Gland/physiology ; Species Specificity
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    NIH panel urges fewer Cesarean births (1980)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1980-10-10
    Description: 〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Kolata, G B -- New York, N.Y. -- Science. 1980 Oct 10;210(4466):176-7.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/7414329" target="_blank"〉PubMed〈/a〉
    Keywords: *Cesarean Section/standards/utilization ; Female ; Humans ; National Institutes of Health (U.S.) ; Pregnancy ; United States
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    Anesthetics as teratogens: nitrous oxide is fetotoxic, xenon is not (1980)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1980-11-21
    Description: Exposure of pregnant rats to the anesthetic nitrous oxide on the ninth day of gestation causes fetal resorption, skeletal anomalies, and macroscopic lesions including encephalocele, anophthalmia, microphthalmia, and gastroschisis. The inert gas xenon, which has anesthetic properties similar to those of nitrous oxide, does not cause teratogenic effects under the same experimental conditions.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Lane, G A -- Nahrwold, M L -- Tait, A R -- Taylor-Busch, M -- Cohen, P J -- Beaudoin, A R -- New York, N.Y. -- Science. 1980 Nov 21;210(4472):899-901.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/7434002" target="_blank"〉PubMed〈/a〉
    Keywords: Anesthetics/*adverse effects ; Animals ; Female ; Nitrous Oxide/*toxicity ; Pregnancy ; Rats ; Structure-Activity Relationship ; *Teratogens ; Xenon/*toxicity
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    High-affinity [3H]imipramine binding in rat hypothalamus: association with uptake of serotonin but not of norepinephrine (1980)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1980-12-05
    Description: Inhibition of the binding of [3H]imipramine and inhibition of the uptake of [3H]serotonin and [3H]norepinephrine by a series of antidepressants and other drugs were studied in the rat hypothalamus. No correlation was found between the potencies of these drugs for the inhibition of [3H]imipramine binding and the inhibition of [3H]norepinephrine uptake. There was, however, a highly significant correlation between the potencies of these drugs for the inhibition of [3H]serotonin uptake. These results suggest that high-affinity [3H]imipramine binding might be associated with the mechanism of serotonin uptake in the brain.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Langer, S Z -- Moret, C -- Raisman, R -- Dubocovich, M L -- Briley, M -- New York, N.Y. -- Science. 1980 Dec 5;210(4474):1133-5.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/7444441" target="_blank"〉PubMed〈/a〉
    Keywords: Animals ; Antidepressive Agents/pharmacology ; Biological Transport/drug effects ; *Carrier Proteins ; Hypothalamus/*metabolism ; Imipramine/*metabolism ; Norepinephrine/*metabolism ; Rats ; Receptors, Drug/*metabolism ; Serotonin/*metabolism ; Structure-Activity Relationship
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  • 138
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    Caffeine study (1980)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1980-03-21
    Description: 〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Lechat, M F -- Borlee, I -- Bouckaert, A -- Misson, C -- New York, N.Y. -- Science. 1980 Mar 21;207(4437):1296-7.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/7355288" target="_blank"〉PubMed〈/a〉
    Keywords: Abnormalities, Drug-Induced/*etiology ; Caffeine/*adverse effects ; Female ; Humans ; Infant, Newborn ; Pregnancy ; *Teratogens
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  • 139
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    Mouse globin system: a functional and evolutionary analysis (1980)
    American Association for the Advancement of Science (AAAS)
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    Publication Date: 1980-09-19
    Description: Structural and functional analysis of the mouse alpha-globin and beta-globin genes reveals that the globin genes are encoded in discontinous bits of coding information and that each gene locus is much more complex than was originally supposed. Each seems to consist of an array of several authentic genes as well as several apparently inactive pseudogenes. Comparison of the sequences of some of these genes to one another indicates that chromosomal DNA is a dynamic structure. Flanking and intervening sequences change in two ways: quickly, by duplication and extensive insertions and deletions, and slowly, by point mutation. Active coding sequences are usually limited to the slower mode of evolution. In addition to identifying fast and slow modes of evolution, it has also been possible to test the function of several signals that surround these genes and to identify those that appear to play a role in gene expression.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Leder, P -- Hansen, J N -- Konkel, D -- Leder, A -- Nishioka, Y -- Talkington, C -- New York, N.Y. -- Science. 1980 Sep 19;209(4463):1336-42.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/7414319" target="_blank"〉PubMed〈/a〉
    Keywords: Animals ; Base Sequence ; *Biological Evolution ; Genes ; Globins/*genetics ; Mice ; Nucleic Acid Hybridization ; Nucleic Acid Precursors/genetics ; RNA, Messenger/genetics/metabolism
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  • 140
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    Mental symptoms in Huntington's disease and a possible primary aminergic neuron lesion (1980)
    American Association for the Advancement of Science (AAAS)
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    Publication Date: 1980-12-19
    Description: Monoamine oxidase activity was higher in the cerebral cortex and basal ganglia of patients dying from Huntington's disease than in controls. Enzyme kinetics and multiple substrate studies indicated that the increased activity was due to elevated concentrations of monoamine oxidase type B. Concentrations of homovanillic acid were increased in the cerebral cortex but not in the basal ganglia of brains of patients with Huntington's disease. These changes may represent a primary aminergic lesion that could underlie some of the mental symptoms of this disease.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Mann, J J -- Stanley, M -- Gershon, S -- Rossor, M -- New York, N.Y. -- Science. 1980 Dec 19;210(4476):1369-71.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/6449080" target="_blank"〉PubMed〈/a〉
    Keywords: Basal Ganglia/*enzymology ; Cerebral Cortex/*enzymology ; Dopamine/physiology ; Female ; Homovanillic Acid/*metabolism ; Humans ; Huntington Disease/complications/*physiopathology ; Male ; Monoamine Oxidase/*metabolism ; Phenylacetates/*metabolism ; Psychotic Disorders/etiology/physiopathology ; Substrate Specificity
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  • 141
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    Evolutionary theory under fire (1980)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1980-11-21
    Description: 〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Lewin, R -- New York, N.Y. -- Science. 1980 Nov 21;210(4472):883-7.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/6107993" target="_blank"〉PubMed〈/a〉
    Keywords: Adaptation, Biological ; *Biological Evolution ; Chicago ; Congresses as Topic ; Fossils ; Gene Frequency ; Models, Theoretical ; Mutation ; Time Factors
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  • 142
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    AMIS negative on aspirin and heart attacks (1980)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1980-02-22
    Description: 〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Marx, J L -- New York, N.Y. -- Science. 1980 Feb 22;207(4433):859-60.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/6986648" target="_blank"〉PubMed〈/a〉
    Keywords: Aspirin/*therapeutic use ; Blood Coagulation/drug effects ; Clinical Trials as Topic ; Female ; Humans ; Ischemic Attack, Transient/prevention & control ; Male ; Myocardial Infarction/*prevention & control ; Time Factors
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  • 143
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    Lactate dehydrogenases of Atlantic hagfish: physiological and evolutionary implications of a primitive heart isozyme (1980)
    American Association for the Advancement of Science (AAAS)
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    Publication Date: 1980-02-15
    Description: Isozymes of lactate dehydrogenase from heart and muscle of Atlantic hagfish show less functional divergence than those from other fishes and higher vertebrates. The enzyme from hagfish heart (B4) displays a higher Michaelis constant for pyruvate and lower substrate inhibition at moderate pyruvate concentrations than heart isozymes from other species. These properties support the hypothesis that the ancestral vertebrate lactate dehydrogenase was a muscle (A4)-type enzyme and also suggest a role for the B4 enzyme in the unusual physiology of hagfish cardiac tissue which functions under sustained hypoxic conditions.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Sidell, B D -- Beland, K F -- New York, N.Y. -- Science. 1980 Feb 15;207(4432):769-70.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/7352286" target="_blank"〉PubMed〈/a〉
    Keywords: Anaerobiosis ; Animals ; *Biological Evolution ; Energy Metabolism ; Fishes/genetics/*physiology ; Genes ; Isoenzymes ; Kinetics ; L-Lactate Dehydrogenase/*genetics/metabolism ; Muscles/*enzymology ; Myocardium/enzymology ; Pyruvates/metabolism
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  • 144
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    Monkey responses to three different alarm calls: evidence of predator classification and semantic communication (1980)
    American Association for the Advancement of Science (AAAS)
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    Publication Date: 1980-11-14
    Description: Vervet monkeys give different alarm calls to different predators. Recordings of the alarms played back when predators were absent caused the monkeys to run into trees for leopard alarms, look up for eagle alarms, and look down for snake alarms. Adults call primarily to leopards, martial eagles, and pythons, but infants give leopard alarms to various mammals, eagle alarms to many birds, and snake alarms to various snakelike objects. Predator classification improves with age and experience.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Seyfarth, R M -- Cheney, D L -- Marler, P -- MH07446/MH/NIMH NIH HHS/ -- New York, N.Y. -- Science. 1980 Nov 14;210(4471):801-3.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/7433999" target="_blank"〉PubMed〈/a〉
    Keywords: *Animal Communication ; Animals ; Behavior, Animal/*physiology ; Cercopithecidae/*physiology ; *Fear ; Female ; Male ; Predatory Behavior ; Vocalization, Animal
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    The testicular feminized rat: a naturally occurring model of androgen independent brain masculinization (1980)
    American Association for the Advancement of Science (AAAS)
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    Publication Date: 1980-07-18
    Description: Although genotypically male (XY), the testicular feminized rat develops as an anatomic female because of an inherited deficiency in intracellular androgen receptors that prevents androgen imprinting of sexual primordia. However, the ability of testicular feminized rats to exhibit male-like sexual behavior and little feminine sexual behavior suggests that the brain can be masculinized without androgens.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Shapiro, B H -- Levine, D C -- Adler, N T -- New York, N.Y. -- Science. 1980 Jul 18;209(4454):418-20.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/7384816" target="_blank"〉PubMed〈/a〉
    Keywords: Androgen-Insensitivity Syndrome/*physiopathology ; Animals ; Brain/*physiopathology ; Castration ; Estradiol/pharmacology ; Female ; Male ; Posture ; Rats ; Sex Factors ; *Sexual Behavior, Animal/drug effects ; Testosterone/pharmacology
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    Synthesis of human plasminogen by the liver (1980)
    American Association for the Advancement of Science (AAAS)
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    Publication Date: 1980-05-30
    Description: Genetic types of plasminogen were determined from a donor and a recipient before and after hepatic homotransplantation. Examination of the plasminogen types demonstrated that the liver is the principal site of synthesis of human plasminogen.〈br /〉〈br /〉〈a href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2981173/" target="_blank"〉〈img src="https://static.pubmed.gov/portal/portal3rc.fcgi/4089621/img/3977009" border="0"〉〈/a〉   〈a href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2981173/" target="_blank"〉This paper as free author manuscript - peer-reviewed and accepted for publication〈/a〉〈br /〉〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Raum, D -- Marcus, D -- Alper, C A -- Levey, R -- Taylor, P D -- Starzl, T E -- R01 AM007772/AM/NIADDK NIH HHS/ -- New York, N.Y. -- Science. 1980 May 30;208(4447):1036-7.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/6990488" target="_blank"〉PubMed〈/a〉
    Keywords: Female ; Humans ; Liver/*metabolism ; Liver Transplantation ; Male ; Plasminogen/*biosynthesis/genetics ; Polymorphism, Genetic ; Transplantation, Homologous
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  • 147
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    Progesterone administration in vivo stimulates release of luteinizing hormone-releasing hormone in vitro (1980)
    American Association for the Advancement of Science (AAAS)
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    Publication Date: 1980-05-30
    Description: The release of luteinizing hormone-releasing hormone (LHRH) from tissue from the mediobasal hypothalamic-anterior hypothalamic-preoptic area of prepuberal female rats was measured in a perfusion system. Measurements were also made of the concentrations of LHRH in these tissue fragments and of luteinizing hormone in serum obtained when the rats were killed. Four groups of immature rats were studied: intact, ovariectomized, ovariectomized and implanted with estradiol-containing capsules, and ovariectomized rats primed with estradiol and injected with progesterone. The release of LHRH from the tissue of ovariectomized animals was significantly less than that of intact females and was not modified when the ovariectomized rats received estradiol. However, there was a four- to fivefold increase in LHRH release from tissue of ovariectomized rats primed with estradiol when they were killed 6 hours after they received an injection of progesterone. The concentrations of LHRH in tissue and of luteinizing hormone in serum varied among groups and with the time of day that the animals were killed. The interactions among luteinizing hormone, gonadal steroids, and the photoperiod seem to set the appropriate conditions for neural processes triggering a complete and normal release of luteinizing hormone.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Ramirez, V D -- Dluzen, D -- Lin, D -- New York, N.Y. -- Science. 1980 May 30;208(4447):1037-9.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/6990489" target="_blank"〉PubMed〈/a〉
    Keywords: Animals ; Castration ; Circadian Rhythm ; Estradiol/pharmacology ; Female ; Gonadotropin-Releasing Hormone/*metabolism ; Hypothalamus/*metabolism ; Hypothalamus, Anterior/metabolism ; Light ; Luteinizing Hormone/blood ; Preoptic Area/metabolism ; Progesterone/*pharmacology ; Rats
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  • 148
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    Esterase 6 and reproduction in Drosophila melanogaster (1980)
    American Association for the Advancement of Science (AAAS)
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    Publication Date: 1980-03-28
    Description: A nonspecific carboxylesterase (esterase 6) of Drosophila melanogaster shows greater activity in adult males than in females and is highly concentrated in the anterior ejaculatory duct of the reproductive tract of the male. Esterase 6 is depleted in males by copulation and is transferred to females early during copulation as a component of the seminal fluid. That esterase 6 may be involved in a system controlling the timing of remating is suggested by differences in the activity of this enzyme in a strain of Drosophila selected for a decrease in time to remating and by differences in the timing of remating in females initially inseminated by males lacking or having active esterase 6.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Richmond, R C -- Gilbert, D G -- Sheehan, K B -- Gromko, M H -- Butterworth, F M -- New York, N.Y. -- Science. 1980 Mar 28;207(4438):1483-5.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/6767273" target="_blank"〉PubMed〈/a〉
    Keywords: Animals ; Carboxylic Ester Hydrolases/genetics/*metabolism ; Drosophila melanogaster/*enzymology/physiology ; Female ; Genitalia, Female/enzymology ; Male ; Polymorphism, Genetic ; Reproduction ; Semen/enzymology ; Sexual Behavior, Animal
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    N-Formylmethionyl peptide receptors on equine leukocytes initiate secretion but not chemotaxis (1980)
    American Association for the Advancement of Science (AAAS)
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    Publication Date: 1980-07-25
    Description: The chemotaxis of leukocytes appears to be initiated by the binding of chemotactic factors to the surface of these cells. N-Formylated peptides induce chemotaxis and lysosomal enzyme secretion of leukocytes; because these peptides are available in a purified radiolabeled form, they have been useful in the characterization of receptors for chemotactic factors. Equine polymorphonuclear leukocytes secrete lysosomal enzymes but do not exhibit chemotaxis in respone to the N-formylated peptides, even though they have a high-affinity cell surface receptor for these agents. The specificity of the equine receptor resembles the specificity of the receptor on chemotactically responsive leukocytes from other species. Equine polymorphonuclear leukocytes may thus be an excellent model for the study of the events that lead to a biological response following receptor occupancy.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Snyderman, R -- Pike, M C -- New York, N.Y. -- Science. 1980 Jul 25;209(4455):493-5.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/6248959" target="_blank"〉PubMed〈/a〉
    Keywords: Animals ; Chemotaxis ; Horses ; Kinetics ; Leukocytes/*physiology/secretion ; Oligopeptides/blood/*physiology ; Receptors, Cell Surface/*physiology ; Receptors, Formyl Peptide ; Structure-Activity Relationship
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    The role of zinc and follicle cells in insulin-initiated meiotic maturation of Xenopus laevis oocytes (1980)
    American Association for the Advancement of Science (AAAS)
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    Publication Date: 1980-11-21
    Description: 〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Wallace, R A -- Misulovin, Z -- New York, N.Y. -- Science. 1980 Nov 21;210(4472):928-30.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/7001631" target="_blank"〉PubMed〈/a〉
    Keywords: Animals ; Cell Nucleus/ultrastructure ; Female ; Insulin/*physiology ; Meiosis ; Oocytes/physiology ; *Oogenesis ; Ovarian Follicle/*physiology ; Pronase/metabolism ; Zinc/*physiology
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  • 151
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    Tumoricidal response induced by cytosine arabinoside after plasma perfusion over protein A (1980)
    American Association for the Advancement of Science (AAAS)
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    Publication Date: 1980-09-12
    Description: In dogs with spontaneous mammary adenocarcinomas, a single nontoxic infusion of cytosine arabinoside after extracorporeal perfusion of plasms over immobilized protein A resulted in a necrotizing response rapid in onset and specific for tumorous tissue. Gross tumoricidal reactions 12 hours after this combined treatment exceeded the algebraic sum of responses to cytosine arabinoside and protein A perfusion treatments alone in the same dogs, implying a synergistic effect between the two. The magnitude, rapidity, and specificity of the tumoricidal response after the combined treatment suggests that it may be an effective chemimmunotherapeutic approach to breast adenocarcinoma.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Terman, D S -- Yamamoto, T -- Tillquist, R L -- Henry, J F -- Cook, G L -- Silvers, A -- Shearer, W T -- New York, N.Y. -- Science. 1980 Sep 12;209(4462):1257-9.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/7403885" target="_blank"〉PubMed〈/a〉
    Keywords: Adenocarcinoma/*therapy ; Animals ; Antibodies, Neoplasm ; Cytarabine/*administration & dosage/therapeutic use ; Dogs ; Female ; Immunotherapy ; Mammary Neoplasms, Experimental/immunology/pathology/*therapy ; Necrosis ; Perfusion ; Staphylococcal Protein A/immunology/*therapeutic use ; Staphylococcus aureus/immunology
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  • 152
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    Cell growth with trans fatty acids is affected by adenosine 3',5'-monophosphate and membrane fluidity (1980)
    American Association for the Advancement of Science (AAAS)
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    Publication Date: 1980-02-15
    Description: Two positional isomers (9 and 11) of trans octadecenoates did not support growth on glucose of an Escherichia coli mutant that requires unsaturated fatty acids. However, the trans fatty acids provided sufficient fluidity to produce much higher cell yields when the concentration of adenosine 3',5'-monophosphate was raised. The effectiveness of the trans acids rose from 0 to 1 cell per femtomole to 15 to 20 cells per femtomole as the concentration of adenosine 3',5'-monophosphate was increased. The corresponding cis positional isomers supported high yields (35 to 40 cells per femtomole) independent of supplementation. The enhanced growth with adenosine 3',5'-monophosphate supplementation is not due to an increased uptake and incorporation of the trans isomers relative to the cis isomers, since the 9-trans isomer was incorporated more rapidly than the 9-cis isomer into the membrane phospholipids under all growth conditions and represented 21 +/- 2 mole percent of the acids. The finding that cells growing with trans fatty acid isomers have a higher requirement for adenosine 3',5'-monophosphate may indicate that some fatty acids can alter the metabolic regulation normally exerted by the cyclic nucleotide.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Tsao, Y K -- Lands, W E -- New York, N.Y. -- Science. 1980 Feb 15;207(4432):777-9.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/6243419" target="_blank"〉PubMed〈/a〉
    Keywords: Cell Division ; Cyclic AMP/*metabolism ; Escherichia coli/*growth & development/metabolism ; Fatty Acids, Nonesterified/*physiology ; Isomerism ; *Membrane Fluidity ; Membrane Lipids/metabolism ; Structure-Activity Relationship
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    Gonadal steroids: effects on excitability of hippocampal pyramidal cells (1980)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1980-08-29
    Description: Electrophysiological field potentials from hippocampal slices of rat brain show sex-linked differences in response to 1 X 10(-10)M concentrations of estradiol and testosterone added to the incubation medium. Slices from male rats show increased excitability to estradiol and not to testosterone. Slices from female rats are not affected by estradiol, but slices from female rats in diestrus show increased excitability in response to testosterone whereas slices from females in proestrus show decreased excitability.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Teyler, T J -- Vardaris, R M -- Lewis, D -- Rawitch, A B -- New York, N.Y. -- Science. 1980 Aug 29;209(4460):1017-8.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/7190730" target="_blank"〉PubMed〈/a〉
    Keywords: Action Potentials/drug effects ; Animals ; Biotransformation ; Diestrus ; Estradiol/metabolism/*pharmacology ; *Estrus ; Female ; Hippocampus/*drug effects ; Male ; Membrane Potentials/drug effects ; Pregnancy ; Proestrus ; Pyramidal Tracts/*drug effects ; Rats ; Sex Differentiation ; Testosterone/*pharmacology
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
    Published by American Association for the Advancement of Science (AAAS)
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  • 154
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    Mouse immunoglobulin D: messenger RNA and genomic DNA sequences (1980)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1980-09-19
    Description: The molecular structure of a mouse immunoglobulin D from a plasmacytoma tumor and that of the normal mouse gene coding for immunoglobulin D are presented. The DNA sequence results indicate an unusual structure for the tumor delta chain in two respects: (i) Only two constant (C) region domains, termed C delta 1 and C delta 3 by homology considerations, are found; the two domains are separated by an unusual hinge region C delta H that lacks cysteine residues and thus cannot provide the covalent cross-links between heavy chains typically seen in immunoglobulins. The two domains and hinge are all coded on separate exons. (ii) At the carboxyl end of the delta chain there is a stretch of 26 amino acids that is coded from an exon located 2750 to 4600 base pairs downstream from the rest of the gene. Analogy with immunoglobulin M suggests that this distally coded segment C delta DC may have a membrane-binding function; however, it is only moderately hydrophobic. A fifth potential exon (C delta AC), located adjacent to the 3' (carboxyl) end of C delta 3, could code for a stretch of 49 amino acids. The tumor's expression of the delta gene may be aberrant, but the simplest interpretation would be that this tumor expresses one of the several biologically significant forms of the delta chain.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Tucker, P W -- Liu, C P -- Mushinski, J F -- Blattner, F R -- New York, N.Y. -- Science. 1980 Sep 19;209(4463):1353-60.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/6968091" target="_blank"〉PubMed〈/a〉
    Keywords: Amino Acid Sequence ; Animals ; B-Lymphocytes/*immunology ; Base Sequence ; *Genes ; Glycoproteins/genetics ; Immunoglobulin Constant Regions/genetics ; Immunoglobulin D/*genetics ; Mice ; Myeloma Proteins/genetics ; RNA, Messenger/*genetics ; Receptors, Antigen, B-Cell/genetics ; Structure-Activity Relationship
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
    Published by American Association for the Advancement of Science (AAAS)
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  • 155
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    Prostaglandin A compounds as antiviral agents (1980)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1980-08-29
    Description: Prostaglandins of the A series strongly inhibit the production of Sendai virus in African green monkey kidney cells and are able to prevent the establishment of persistent infection ("carrier" state). This action is specific for prostaglandin A and is not due to alteration in the host cell metabolism or in the virus infectivity. The possibility that this effect is mediated by interferon is discussed.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Santoro, M G -- Benedetto, A -- Carruba, G -- Garaci, E -- Jaffe, B M -- New York, N.Y. -- Science. 1980 Aug 29;209(4460):1032-4.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/6157190" target="_blank"〉PubMed〈/a〉
    Keywords: Animals ; Arachidonic Acids/pharmacology ; Cell Line ; Dose-Response Relationship, Drug ; Haplorhini ; Interferons/pharmacology ; Parainfluenza Virus 1, Human/*drug effects ; Prostaglandins/pharmacology ; Prostaglandins A/*pharmacology ; Structure-Activity Relationship ; Thromboxanes/pharmacology ; Virus Replication/*drug effects
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
    Published by American Association for the Advancement of Science (AAAS)
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  • 156
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    Primate memory: retention of serial list items by a rhesus monkey (1980)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1980-08-22
    Description: A rhesus monkey correctly recognized 86 and 81 percent of 10- and 20-item lists, respectively. It serial position curve was similar in form to a human's curve, revealing prominent primacy and recency effects. The key to these findings was in minimizing proactive interference through the use of a large pool of 211 color photographs.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Sands, S F -- Wright, A A -- New York, N.Y. -- Science. 1980 Aug 22;209(4459):938-40.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/6773143" target="_blank"〉PubMed〈/a〉
    Keywords: Adult ; Animals ; Female ; Haplorhini ; Humans ; Macaca/*physiology ; Macaca mulatta/*physiology ; Male ; Memory/*physiology ; Memory, Short-Term/physiology ; Methods ; Retention (Psychology)/*physiology
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
    Published by American Association for the Advancement of Science (AAAS)
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  • 157
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    Artificial sweetener use and bladder cancer: a case-control study (1980)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1980-03-14
    Description: In a case-control study of 302 male and 65 female bladder cancer patients and an equal number of other patients matched to them in age, sex, hospital, and hospital-room status, no association was found between use of artificial sweeteners or diet beverages and bladder cancer. No dose-response was observed with respect to quantity or duration of use of the two combined. No evidence was found to suggest that artificial sweeteners or diet beverages promote the tumorigenic effect of tobacco smoking. Artificial sweetener and diet beverage use strongly reflected socioeconomic status among controls with various diagnoses.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Wynder, E L -- Stellman, S D -- New York, N.Y. -- Science. 1980 Mar 14;207(4436):1214-6.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/7355283" target="_blank"〉PubMed〈/a〉
    Keywords: Female ; Humans ; Male ; Sex Factors ; Smoking/*complications ; Sweetening Agents/*adverse effects ; Urinary Bladder Neoplasms/chemically induced/*etiology
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
    Published by American Association for the Advancement of Science (AAAS)
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