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  • American Association for the Advancement of Science (AAAS)  (2,992)
  • 1985-1989  (2,992)
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  • 1
    Publication Date: 1989-12-15
    Description: Voyager 2 images of Neptune reveal a windy planet characterized by bright clouds of methane ice suspended in an exceptionally clear atmosphere above a lower deck of hydrogen sulfide or ammonia ices. Neptune's atmosphere is dominated by a large anticyclonic storm system that has been named the Great Dark Spot (GDS). About the same size as Earth in extent, the GDS bears both many similarities and some differences to the Great Red Spot of Jupiter. Neptune's zonal wind profile is remarkably similar to that of Uranus. Neptune has three major rings at radii of 42,000, 53,000, and 63,000 kilometers. The outer ring contains three higher density arc-like segments that were apparently responsible for most of the ground-based occultation events observed during the current decade. Like the rings of Uranus, the Neptune rings are composed of very dark material; unlike that of Uranus, the Neptune system is very dusty. Six new regular satellites were found, with dark surfaces and radii ranging from 200 to 25 kilometers. All lie inside the orbit of Triton and the inner four are located within the ring system. Triton is seen to be a differentiated body, with a radius of 1350 kilometers and a density of 2.1 grams per cubic centimeter; it exhibits clear evidence of early episodes of surface melting. A now rigid crust of what is probably water ice is overlain with a brilliant coating of nitrogen frost, slightly darkened and reddened with organic polymer material. Streaks of organic polymer suggest seasonal winds strong enough to move particles of micrometer size or larger, once they become airborne. At least two active plumes were seen, carrying dark material 8 kilometers above the surface before being transported downstream by high level winds. The plumes may be driven by solar heating and the subsequent violent vaporization of subsurface nitrogen.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Smith, B A -- Soderblom, L A -- Banfield, D -- Barnet, C -- Basilevsky, A T -- Beebe, R F -- Bollinger, K -- Boyce, J M -- Brahic, A -- Briggs, G A -- Brown, R H -- Chyba, C -- Collins, S A -- Colvin, T -- Cook, A F 2nd -- Crisp, D -- Croft, S K -- Cruikshank, D -- Cuzzi, J N -- Danielson, G E -- Davies, M E -- De Jong, E -- Dones, L -- Godfrey, D -- Goguen, J -- Grenier, I -- Haemmerle, V R -- Hammel, H -- Hansen, C J -- Helfenstein, C P -- Howell, C -- Hunt, G E -- Ingersoll, A P -- Johnson, T V -- Kargel, J -- Kirk, R -- Kuehn, D I -- Limaye, S -- Masursky, H -- McEwen, A -- Morrison, D -- Owen, T -- Owen, W -- Pollack, J B -- Porco, C C -- Rages, K -- Rogers, P -- Rudy, D -- Sagan, C -- Schwartz, J -- Shoemaker, E M -- Showalter, M -- Sicardy, B -- Simonelli, D -- Spencer, J -- Sromovsky, L A -- Stoker, C -- Strom, R G -- Suomi, V E -- Synott, S P -- Terrile, R J -- Thomas, P -- Thompson, W R -- Verbiscer, A -- Veverka, J -- New York, N.Y. -- Science. 1989 Dec 15;246(4936):1422-49.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/17755997" target="_blank"〉PubMed〈/a〉
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  • 2
    Publication Date: 1986-07-04
    Description: Voyager 2 images of the southern hemisphere of Uranus indicate that submicrometersize haze particles and particles of a methane condensation cloud produce faint patterns in the atmosphere. The alignment of the cloud bands is similar to that of bands on Jupiter and Saturn, but the zonal winds are nearly opposite. At mid-latitudes (-70 degrees to -27 degrees ), where winds were measured, the atmosphere rotates faster than the magnetic field; however, the rotation rate of the atmosphere decreases toward the equator, so that the two probably corotate at about -20 degrees . Voyager images confirm the extremely low albedo of the ring particles. High phase angle images reveal on the order of 10(2) new ringlike features of very low optical depth and relatively high dust abundance interspersed within the main rings, as well as a broad, diffuse, low optical depth ring just inside the main rings system. Nine of the newly discovered small satellites (40 to 165 kilometers in diameter) orbit between the rings and Miranda; the tenth is within the ring system. Two of these small objects may gravitationally confine the e ring. Oberon and Umbriel have heavily cratered surfaces resembling the ancient cratered highlands of Earth's moon, although Umbriel is almost completely covered with uniform dark material, which perhaps indicates some ongoing process. Titania and Ariel show crater populations different from those on Oberon and Umbriel; these were probably generated by collisions with debris confined to their orbits. Titania and Ariel also show many extensional fault systems; Ariel shows strong evidence for the presence of extrusive material. About halfof Miranda's surface is relatively bland, old, cratered terrain. The remainder comprises three large regions of younger terrain, each rectangular to ovoid in plan, that display complex sets of parallel and intersecting scarps and ridges as well as numerous outcrops of bright and dark materials, perhaps suggesting some exotic composition.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Smith, B A -- Soderblom, L A -- Beebe, R -- Bliss, D -- Boyce, J M -- Brahic, A -- Briggs, G A -- Brown, R H -- Collins, S A -- Cook, A F 2nd -- Croft, S K -- Cuzzi, J N -- Danielson, G E -- Davies, M E -- Dowling, T E -- Godfrey, D -- Hansen, C J -- Harris, C -- Hunt, G E -- Ingersoll, A P -- Johnson, T V -- Krauss, R J -- Masursky, H -- Morrison, D -- Owen, T -- Plescia, J B -- Pollack, J B -- Porco, C C -- Rages, K -- Sagan, C -- Shoemaker, E M -- Sromovsky, L A -- Stoker, C -- Strom, R G -- Suomi, V E -- Synnott, S P -- Terrile, R J -- Thomas, P -- Thompson, W R -- Veverka, J -- New York, N.Y. -- Science. 1986 Jul 4;233(4759):43-64.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/17812889" target="_blank"〉PubMed〈/a〉
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  • 3
    Publication Date: 1989-08-04
    Description: Understanding the cause of differences among general circulation model projections of carbon dioxide-induced climatic change is a necessary step toward improving the models. An intercomparison of 14 atmospheric general circulation models, for which sea surface temperature perturbations were used as a surrogate climate change, showed that there was a roughly threefold variation in global climate sensitivity. Most of this variation is attributable to differences in the models' depictions of cloud-climate feedback, a result that emphasizes the need for improvements in the treatment of clouds in these models if they are ultimately to be used as climatic predictors.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Cess, R D -- Potter, G L -- Blanchet, J P -- Boer, G J -- Ghan, S J -- Kiehl, J T -- LE Treut, H -- Li, Z X -- Liang, X Z -- Mitchell, J F -- Morcrette, J J -- Randall, D A -- Riches, M R -- Roeckner, E -- Schlese, U -- Slingo, A -- Taylor, K E -- Washington, W M -- Wetherald, R T -- Yagai, I -- New York, N.Y. -- Science. 1989 Aug 4;245(4917):513-6.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/17750262" target="_blank"〉PubMed〈/a〉
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  • 4
    Publication Date: 1989-12-15
    Description: Results from the occultation of the sun by Neptune imply a temperature of 750 +/- 150 kelvins in the upper levels of the atmosphere (composed mostly of atomic and molecular hydrogen) and define the distributions of methane, acetylene, and ethane at lower levels. The ultraviolet spectrum of the sunlit atmosphere of Neptune resembles the spectra of the Jupiter, Saturn, and Uranus atmospheres in that it is dominated by the emissions of H Lyman alpha (340 +/- 20 rayleighs) and molecular hydrogen. The extreme ultraviolet emissions in the range from 800 to 1100 angstroms at the four planets visited by Voyager scale approximately as the inverse square of their heliocentric distances. Weak auroral emissions have been tentatively identified on the night side of Neptune. Airglow and occultation observations of Triton's atmosphere show that it is composed mainly of molecular nitrogen, with a trace of methane near the surface. The temperature of Triton's upper atmosphere is 95 +/- 5 kelvins, and the surface pressure is roughly 14 microbars.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Broadfoot, A L -- Atreya, S K -- Bertaux, J L -- Blamont, J E -- Dessler, A J -- Donahue, T M -- Forrester, W T -- Hall, D T -- Herbert, F -- Holberg, J B -- Hunter, D M -- Krasnopolsky, V A -- Linick, S -- Lunine, J I -- McConnell, J C -- Moos, H W -- Sandel, B R -- Schneider, N M -- Shemansky, D E -- Smith, G R -- Strobel, D F -- Yelle, R V -- New York, N.Y. -- Science. 1989 Dec 15;246(4936):1459-66.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/17756000" target="_blank"〉PubMed〈/a〉
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  • 5
    Publication Date: 1987-01-23
    Description: Acid deposition and photochemical smog are urban air pollution problems, and they remain localized as long as the sulfur, nitrogen, and hydrocarbon pollutants are confined to the lower troposphere (below about 1-kilometer altitude) where they are short-lived. If, however, the contaminants are rapidly transported to the upper troposphere, then their atmospheric residence times grow and their range of influence expands dramatically. Although this vertical transport ameliorates some of the effects of acid rain by diluting atmospheric acids, it exacerbates global tropospheric ozone production by redistributing the necessary nitrogen catalysts. Results of recent computer simulations suggest that thunderstorms are one means of rapid vertical transport. To test this hypothesis, several research aircraft near a midwestern thunderstrom measured carbon monoxide, hydrocarbons, ozone, and reactive nitrogen compounds. Their concentrations were much greater in the outflow region of the storm, up to 11 kilometers in altitude, than in surrounding air. Trace gas measurements can thus be used to track the motion of air in and around a cloud. Thunderstorms may transform local air pollution problems into regional or global atmospheric chemistry problems.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Dickerson, R R -- Huffman, G J -- Luke, W T -- Nunnermacker, L J -- Pickering, K E -- Leslie, A C -- Lindsey, C G -- Slinn, W G -- Kelly, T J -- Daum, P H -- Delany, A C -- Greenberg, J P -- Zimmerman, P R -- Boatman, J F -- Ray, J D -- Stedman, D H -- New York, N.Y. -- Science. 1987 Jan 23;235(4787):460-5.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/17810340" target="_blank"〉PubMed〈/a〉
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  • 6
    Publication Date: 1988-04-29
    Description: Pertussis toxin is produced by the causative agent of whooping cough, Bordetella pertussis, and is an adenosine diphosphate (ADP)-ribosyltransferase capable of covalently modifying and thereby inactivating many eukaryotic G proteins involved in cellular metabolism. The toxin is a principal determinant of virulence in whooping cough and is a primary candidate for an acellular pertussis vaccine, yet it is unclear whether the ADP-ribosyltransferase activity is required for both pathogenic and immunoprotective activities. A B. pertussis strain that produced an assembled pertussis holotoxin with only 1 percent of the ADP-ribosyltransferase activity of the native toxin was constructed and was found to be deficient in pathogenic activities associated with B. pertussis including induction of leukocytosis, potentiation of anaphylaxis, and stimulation of histamine sensitivity. Moreover, this mutant strain failed to function as an adjuvant and was less effective in protecting mice from intracerebral challenge infection. These data suggest that the ADP-ribosyltransferase activity is necessary for both pathogenicity and optimum immunoprotection. These findings bear directly on the design of a nontoxic pertussis vaccine.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Black, W J -- Munoz, J J -- Peacock, M G -- Schad, P A -- Cowell, J L -- Burchall, J J -- Lim, M -- Kent, A -- Steinman, L -- Falkow, S -- AI-22462/AI/NIAID NIH HHS/ -- AI-23945/AI/NIAID NIH HHS/ -- New York, N.Y. -- Science. 1988 Apr 29;240(4852):656-9.〈br /〉〈span class="detail_caption"〉Author address: 〈/span〉Department of Medical Microbiology, Stanford University, CA 94305.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/2896387" target="_blank"〉PubMed〈/a〉
    Keywords: ADP Ribose Transferases ; Adjuvants, Immunologic ; Anaphylaxis/etiology ; Animals ; Antigens/immunology ; Bordetella pertussis/enzymology/genetics/*immunology ; Codon ; Drug Tolerance ; Histamine/pharmacology ; Immunization ; Leukocytosis/etiology ; Macromolecular Substances ; Mice ; Mice, Inbred BALB C ; Mice, Inbred C57BL ; Mutation ; Ovalbumin/immunology ; Pentosyltransferases/*metabolism ; *Pertussis Toxin ; Virulence Factors, Bordetella/genetics/immunology/*metabolism
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  • 7
    Publication Date: 1989-02-10
    Description: Transforming growth factor alpha (TGF-alpha) is produced by and required for the growth of epithelial cells and is angiogenic in vivo. Since epidermal hyperplasia and angiogenesis are hallmarks of psoriasis, TGF-alpha gene expression was analyzed in epidermal biopsies of normal and psoriatic skin. TGF-alpha messenger RNA and protein are much more abundant in lesional psoriatic epidermis than in normal-appearing skin of psoriatic patients or in normal epidermis. In contrast, messenger RNA levels of transforming growth factor beta 1 (TGF-beta 1), which inhibits epithelial cell growth, are not significantly different in normal, uninvolved, and lesional psoriatic epidermis. Thus, psoriatic epidermal hyperplasia may involve increased expression of a keratinocyte mitogen (TGF-alpha) rather than deficient expression of a growth inhibitor (TGF-beta 1).〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Elder, J T -- Fisher, G J -- Lindquist, P B -- Bennett, G L -- Pittelkow, M R -- Coffey, R J Jr -- Ellingsworth, L -- Derynck, R -- Voorhees, J J -- 5-T32-AM07197-10/AM/NIADDK NIH HHS/ -- New York, N.Y. -- Science. 1989 Feb 10;243(4892):811-4.〈br /〉〈span class="detail_caption"〉Author address: 〈/span〉Department of Dermatology, University of Michigan, Ann Arbor 48109.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/2916128" target="_blank"〉PubMed〈/a〉
    Keywords: Blotting, Northern ; Epidermis/physiopathology ; Gene Expression Regulation/drug effects ; Humans ; Immunoassay ; Psoriasis/*genetics ; Transforming Growth Factors/*genetics/metabolism
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  • 8
    Publication Date: 1989-01-06
    Description: Evidence suggests that superconducting, orthorhombic YBa(2)Cu(3)O(6+x)+ (x greater, similar 0.5) is always produced by oxidation of the oxygen-deficient, tetragonal form (x less, similar 0.5) of this phase (commonly referred to as 123). A synthetic route whereby solution-derived, carbon-free precursors are decomposed at 650 degrees to 700 degrees C in inert atmosphere to yield tetragonal 123 is now available. Appropriate precursors include hydrated oxides derived from the hydrolysis of organometallic solutions and aqueous solution-derived hyponitrites. Subsequent oxidation of the tetragonal phase at 400 degrees C results in submicrometer particles of orthorhombic 123. Superconductivity (T(c) onset approximately 87 K) has been confirmed in these materials by both Meissner effect and specific-heat measurements.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Horowitz, H S -- McLain, S J -- Sleight, A W -- Druliner, J D -- Gai, P L -- Vankavelaar, M J -- Wagner, J L -- Biggs, B D -- Poon, S J -- New York, N.Y. -- Science. 1989 Jan 6;243(4887):66-9.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/17780424" target="_blank"〉PubMed〈/a〉
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  • 9
    Publication Date: 1988-07-29
    Description: Interleukin-1 alpha and -1 beta (IL-1 alpha and IL-1 beta) are cytokines that participate in the regulation of immune responses, inflammatory reactions, and hematopoiesis. A direct expression strategy was used to clone the receptor for IL-1 from mouse T cells. The product of the cloned complementary DNA binds both IL-1 alpha and IL-1 beta in a manner indistinguishable from that of the native T cell IL-1 receptor. The extracellular, IL-1 binding portion of the receptor is 319 amino acids in length and is composed of three immunoglobulin-like domains. The cytoplasmic portion of the receptor is 217 amino acids long.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Sims, J E -- March, C J -- Cosman, D -- Widmer, M B -- MacDonald, H R -- McMahan, C J -- Grubin, C E -- Wignall, J M -- Jackson, J L -- Call, S M -- New York, N.Y. -- Science. 1988 Jul 29;241(4865):585-9.〈br /〉〈span class="detail_caption"〉Author address: 〈/span〉Immunex Corporation, Seattle, WA 98101.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/2969618" target="_blank"〉PubMed〈/a〉
    Keywords: Amino Acid Sequence ; Animals ; Base Sequence ; Cloning, Molecular ; DNA/genetics ; Gene Expression Regulation ; Genes, Immunoglobulin ; Interleukin-1/*physiology ; Mice ; Molecular Sequence Data ; *Multigene Family ; Receptors, Immunologic/*genetics ; Receptors, Interleukin-1
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  • 10
    Publication Date: 1989-12-15
    Description: The plasma science experiment on Voyager 2 made observations of the plasma environment in Neptune's magnetosphere and in the surrounding solar wind. Because of the large tilt of the magnetic dipole and fortuitous timing, Voyager entered Neptune's magnetosphere through the cusp region, the first cusp observations at an outer planet. Thus the transition from the magnetosheath to the magnetosphere observed by Voyager 2 was not sharp but rather appeared as a gradual decrease in plasma density and temperature. The maximum plasma density observed in the magnetosphere is inferred to be 1.4 per cubic centimeter (the exact value depends on the composition), the smallest observed by Voyager in any magnetosphere. The plasma has at least two components; light ions (mass, 1 to 5) and heavy ions (mass, 10 to 40), but more precise species identification is not yet available. Most of the plasma is concentrated in a plasma sheet or plasma torus and near closest approach to the planet. A likely source of the heavy ions is Triton's atmosphere or ionosphere, whereas the light ions probably escape from Neptune. The large tilt of Neptune's magnetic dipole produces a dynamic magnetosphere that changes configuration every 16 hours as the planet rotates.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Belcher, J W -- Bridge, H S -- Bagenal, F -- Coppi, B -- Divers, O -- Eviatar, A -- Gordon, G S Jr -- Lazarus, A J -- McNutt, R L Jr -- Ogilvie, K W -- Richardson, J D -- Siscoe, G L -- Sittler, E C Jr -- Steinberg, J T -- Sullivan, J D -- Szabo, A -- Villanueva, L -- Vasyliunas, V M -- Zhang, M -- New York, N.Y. -- Science. 1989 Dec 15;246(4936):1478-83.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/17756003" target="_blank"〉PubMed〈/a〉
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