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  • American Association for the Advancement of Science (AAAS)  (10)
  • PANGAEA
  • 2015-2019
  • 2000-2004  (15)
  • 2002  (15)
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  • 2015-2019
  • 2000-2004  (15)
Year
  • 1
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    Gene expression during the life cycle of Drosophila melanogaster (2002)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 2002-09-28
    Description: Molecular genetic studies of Drosophila melanogaster have led to profound advances in understanding the regulation of development. Here we report gene expression patterns for nearly one-third of all Drosophila genes during a complete time course of development. Mutations that eliminate eye or germline tissue were used to further analyze tissue-specific gene expression programs. These studies define major characteristics of the transcriptional programs that underlie the life cycle, compare development in males and females, and show that large-scale gene expression data collected from whole animals can be used to identify genes expressed in particular tissues and organs or genes involved in specific biological and biochemical processes.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Arbeitman, Michelle N -- Furlong, Eileen E M -- Imam, Farhad -- Johnson, Eric -- Null, Brian H -- Baker, Bruce S -- Krasnow, Mark A -- Scott, Matthew P -- Davis, Ronald W -- White, Kevin P -- Howard Hughes Medical Institute/ -- New York, N.Y. -- Science. 2002 Sep 27;297(5590):2270-5.〈br /〉〈span class="detail_caption"〉Author address: 〈/span〉Department of Biological Sciences, Stanford University, Stanford, CA 94305, USA.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/12351791" target="_blank"〉PubMed〈/a〉
    Keywords: Algorithms ; Animals ; Cluster Analysis ; Drosophila Proteins/genetics/physiology ; Drosophila melanogaster/embryology/*genetics/*growth & development ; Embryo, Nonmammalian/physiology ; Female ; *Gene Expression ; Gene Expression Profiling ; Gene Expression Regulation, Developmental ; *Genes, Insect ; Germ Cells/physiology ; Larva/genetics ; Life Cycle Stages/*genetics ; Male ; Oligonucleotide Array Sequence Analysis ; Organ Specificity ; Pupa/genetics ; RNA, Messenger/genetics/metabolism ; Sex Characteristics ; Transcription, Genetic
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
    Published by American Association for the Advancement of Science (AAAS)
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  • 2
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    Kilimanjaro ice core records: evidence of holocene climate change in tropical Africa (2002)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 2002-10-19
    Description: Six ice cores from Kilimanjaro provide an approximately 11.7-thousand-year record of Holocene climate and environmental variability for eastern equatorial Africa, including three periods of abrupt climate change: approximately 8.3, approximately 5.2, and approximately 4 thousand years ago (ka). The latter is coincident with the "First Dark Age," the period of the greatest historically recorded drought in tropical Africa. Variable deposition of F- and Na+ during the African Humid Period suggests rapidly fluctuating lake levels between approximately 11.7 and 4 ka. Over the 20th century, the areal extent of Kilimanjaro's ice fields has decreased approximately 80%, and if current climatological conditions persist, the remaining ice fields are likely to disappear between 2015 and 2020.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Thompson, Lonnie G -- Mosley-Thompson, Ellen -- Davis, Mary E -- Henderson, Keith A -- Brecher, Henry H -- Zagorodnov, Victor S -- Mashiotta, Tracy A -- Lin, Ping-Nan -- Mikhalenko, Vladimir N -- Hardy, Douglas R -- Beer, Jurg -- New York, N.Y. -- Science. 2002 Oct 18;298(5593):589-93.〈br /〉〈span class="detail_caption"〉Author address: 〈/span〉Byrd Polar Research Center, The Ohio State University, Columbus, OH 43210, USA. thompson.3@osu.edu〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/12386332" target="_blank"〉PubMed〈/a〉
    Print ISSN: 0036-8075
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    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
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  • 3
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    Observational evidence for an active surface reservoir of solid carbon dioxide on Mars (2002)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 2002-01-05
    Description: High-resolution images of the south polar residual cap of Mars acquired in 1999 and 2001 show changes in the configuration of pits, intervening ridges, and isolated mounds. Escarpments have retreated 1 to 3 meters in 1 martian year, changes that are an order of magnitude larger than can be explained by the sublimation of water ice, but close to what is expected for sublimation of carbon dioxide ice. These observations support a 35-year-old conjecture that Mars has a large surface reservoir of solid carbon dioxide. The erosion implies that this reservoir is not in equilibrium with the present environment and that global climate change is occurring on Mars.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Malin, M C -- Caplinger, M A -- Davis, S D -- New York, N.Y. -- Science. 2001 Dec 7;294(5549):2146-8.〈br /〉〈span class="detail_caption"〉Author address: 〈/span〉Malin Space Science Systems, Post Office Box 910148, SanDiego, CA 92191-0148, USA.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/11768358" target="_blank"〉PubMed〈/a〉
    Keywords: Atmosphere ; *Carbon Dioxide ; *Dry Ice ; Extraterrestrial Environment ; *Mars ; Water
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
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  • 4
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    Robotic observations of dust storm enhancement of carbon biomass in the North Pacific (2002)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 2002-10-26
    Description: Two autonomous robotic profiling floats deployed in the subarctic North Pacific on 10 April 2001 provided direct records of carbon biomass variability from surface to 1000 meters below surface at daily and diurnal time scales. Eight months of real-time data documented the marine biological response to natural events, including hydrographic changes, multiple storms, and the April 2001 dust event. High-frequency observations of upper ocean particulate organic carbon variability show a near doubling of biomass in the mixed layer over a 2-week period after the passage of a cloud of Gobi desert dust. The temporal evolution of particulate organic carbon enhancement and an increase in chlorophyll use efficiency after the dust storm suggest a biotic response to a natural iron fertilization by the dust.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Bishop, James K B -- Davis, Russ E -- Sherman, Jeffrey T -- New York, N.Y. -- Science. 2002 Oct 25;298(5594):817-21.〈br /〉〈span class="detail_caption"〉Author address: 〈/span〉Earth Sciences Division, Lawrence Berkeley National Laboratory, 1 Cyclotron Road, MS 90-1116, Berkeley, CA 94708, USA. JKBishop@lbl.gov〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/12399588" target="_blank"〉PubMed〈/a〉
    Keywords: Atmosphere/chemistry ; *Biomass ; Carbon/*analysis ; Chlorophyll/analysis ; *Dust ; Geologic Sediments/chemistry ; Iron/analysis ; Pacific Ocean ; Photosynthesis ; Phytoplankton/*growth & development ; Robotics ; *Seawater ; *Wind
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
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  • 5
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    Immunology. The immunological synapse--a multitasking system (2002)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 2002-02-23
    Description: 〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉van Der Merwe, P Anton -- Davis, Simon J -- New York, N.Y. -- Science. 2002 Feb 22;295(5559):1479-80.〈br /〉〈span class="detail_caption"〉Author address: 〈/span〉Sir William Dunn School of Pathology, University of Oxford, Oxford OX1 3RE, UK. anton.vandermerwe@path.ox.ac.uk〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/11859183" target="_blank"〉PubMed〈/a〉
    Keywords: Abatacept ; Animals ; Antigen-Presenting Cells/*immunology ; Antigens, CD ; Antigens, CD28/immunology/metabolism ; Antigens, CD80/immunology/metabolism ; Antigens, Differentiation/metabolism ; CD4-Positive T-Lymphocytes/immunology ; CD8-Positive T-Lymphocytes/immunology ; CTLA-4 Antigen ; Dimerization ; Histocompatibility Antigens Class II/metabolism ; *Immunoconjugates ; Immunoglobulin alpha-Chains/immunology/metabolism ; Intercellular Junctions/*immunology ; Ligands ; Lipid Bilayers ; Lymphocyte Activation ; Mice ; Peptides/immunology/metabolism ; Receptor Aggregation ; Receptors, Antigen, T-Cell/*immunology ; Signal Transduction ; T-Lymphocytes/*immunology ; Time Factors
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
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  • 6
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    Nuclear safety. Nuclear power plants and their fuel as terrorist targets (2002)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 2002-09-21
    Description: 〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Chapin, Douglas M -- Cohen, Karl P -- Davis, W Kenneth -- Kintner, Edwin E -- Koch, Leonard J -- Landis, John W -- Levenson, Milton -- Mandil, I Harry -- Pate, Zack T -- Rockwell, Theodore -- Schriesheim, Alan -- Simpson, John W -- Squire, Alexander -- Starr, Chauncey -- Stone, Henry E -- Taylor, John J -- Todreas, Neil E -- Wolfe, Bertram -- Zebroski, Edwin L -- New York, N.Y. -- Science. 2002 Sep 20;297(5589):1997-9.〈br /〉〈span class="detail_caption"〉Author address: 〈/span〉MPR Associates, Inc., Alexandria, VA 22314-3230, USA.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/12242425" target="_blank"〉PubMed〈/a〉
    Keywords: *Nuclear Energy ; *Nuclear Reactors ; *Power Plants ; Radioactive Hazard Release ; *Safety ; *Terrorism ; Ukraine ; United States
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
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  • 7
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    Short-lived nuclides in hibonite grains from Murchison: evidence for solar system evolution (2002)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 2002-12-14
    Description: Records of now-extinct short-lived nuclides in meteorites provide information about the formation and evolution of the solar system. We have found excess 10B that we attribute to the decay of short-lived 10Be (half-life 1.5 million years) in hibonite grains from the Murchison meteorite. The grains show no evidence of decay of two other short-lived nuclides-26Al (half-life 700,000 years) and 41Ca (half-life 100,000 years)-that may be present in early solar system solids. One plausible source of the observed 10Be is energetic particle irradiation of material in the solar nebula. An effective irradiation dose of approximately 2 x 10(18) protons per square centimeter with a kinetic energy of 〉/=10 megaelectronvolts per atomic mass unit can explain our measurements. The presence of 10Be, coupled with the absence of 41Ca and 26Al, may rule out energetic particle irradiation as the primary source of 41Ca and 26Al present in some early solar system solids and strengthens the case of a stellar source for 41Ca and 26Al.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Marhas, K K -- Goswami, J N -- Davis, A M -- New York, N.Y. -- Science. 2002 Dec 13;298(5601):2182-5.〈br /〉〈span class="detail_caption"〉Author address: 〈/span〉Physical Research Laboratory, Ahmedabad 380009, India.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/12481135" target="_blank"〉PubMed〈/a〉
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    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
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  • 8
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    Imaging quasiparticle interference in Bi2Sr2CaCu2O8+delta (2002)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 2002-07-27
    Description: Scanning tunneling spectroscopy of the high-Tc superconductor Bi2Sr2CaCu2O8+delta reveals weak, incommensurate, spatial modulations in the tunneling conductance. Images of these energy-dependent modulations are Fourier analyzed to yield the dispersion of their wavevectors. Comparison of the dispersions with photoemission spectroscopy data indicates that quasiparticle interference, due to elastic scattering between characteristic regions of momentum-space, provides a consistent explanation for the conductance modulations, without appeal to another order parameter. These results refocus attention on quasiparticle scattering processes as potential explanations for other incommensurate phenomena in the cuprates. The momentum-resolved tunneling spectroscopy demonstrated here also provides a new technique with which to study quasiparticles in correlated materials.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Hoffman, J E -- McElroy, K -- Lee, D-H -- Lang, K M -- Eisaki, H -- Uchida, S -- Davis, J C -- New York, N.Y. -- Science. 2002 Aug 16;297(5584):1148-51. Epub 2002 Jul 25.〈br /〉〈span class="detail_caption"〉Author address: 〈/span〉Department of Physics, University of California, Berkeley, CA 94720-7300, USA.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/12142440" target="_blank"〉PubMed〈/a〉
    Print ISSN: 0036-8075
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    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
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  • 9
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    Signal transduction. MAP kinase signaling specificity (2002)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 2002-06-29
    Description: 〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Weston, Claire R -- Lambright, David G -- Davis, Roger J -- New York, N.Y. -- Science. 2002 Jun 28;296(5577):2345-7.〈br /〉〈span class="detail_caption"〉Author address: 〈/span〉Howard Hughes Medical Institute and Program in Molecular Medicine, University of Massachusetts Medical School, Worcester, MA 01605, USA.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/12089430" target="_blank"〉PubMed〈/a〉
    Keywords: Amino Acid Motifs ; Binding Sites ; Catalytic Domain ; Crystallography, X-Ray ; DNA-Binding Proteins/chemistry/*metabolism ; MAP Kinase Kinase 3 ; *MAP Kinase Signaling System ; MEF2 Transcription Factors ; Mitogen-Activated Protein Kinase Kinases/chemistry/*metabolism ; Mitogen-Activated Protein Kinases/*chemistry/*metabolism ; Models, Molecular ; Myogenic Regulatory Factors ; Protein Conformation ; Protein Structure, Secondary ; Protein Structure, Tertiary ; Protein-Tyrosine Kinases/chemistry/*metabolism ; Transcription Factors/chemistry/*metabolism ; p38 Mitogen-Activated Protein Kinases
    Print ISSN: 0036-8075
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    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
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  • 10
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    A four unit cell periodic pattern of quasi-particle states surrounding vortex cores in Bi2Sr2CaCu2O8+delta (2002)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 2002-01-19
    Description: Scanning tunneling microscopy is used to image the additional quasi-particle states generated by quantized vortices in the high critical temperature superconductor Bi2Sr2CaCu2O8+delta. They exhibit a copper-oxygen bond-oriented "checkerboard" pattern, with four unit cell (4a0) periodicity and a approximately 30 angstrom decay length. These electronic modulations may be related to the magnetic field-induced, 8a0 periodic, spin density modulations with decay length of approximately 70 angstroms recently discovered in La1.84Sr0.16CuO4. The proposed explanation is a spin density wave localized surrounding each vortex core. General theoretical principles predict that, in the cuprates, a localized spin modulation of wavelength lambda should be associated with a corresponding electronic modulation of wavelength lambda/2, in good agreement with our observations.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Hoffman, J E -- Hudson, E W -- Lang, K M -- Madhavan, V -- Eisaki, H -- Uchida, S -- Davis, J C -- New York, N.Y. -- Science. 2002 Jan 18;295(5554):466-9.〈br /〉〈span class="detail_caption"〉Author address: 〈/span〉Department of Physics, University of California, Berkeley, CA 94720-7300, USA.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/11799234" target="_blank"〉PubMed〈/a〉
    Print ISSN: 0036-8075
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