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  • Chemistry  (93,258)
  • LUNAR AND PLANETARY EXPLORATION  (6,895)
  • Cell & Developmental Biology  (5,177)
  • ASTRONOMY  (2,921)
  • 1980-1984  (41,333)
  • 1975-1979  (35,771)
  • 1960-1964  (21,188)
  • 1930-1934
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  • 1
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    Picosecond chemical and biological events (1978)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1978-10-13
    Description: Picosecond spectroscopy is a relatively new field of science that utilizes ultrashort laser pulses to monitor events taking place in the 10(-12) second regime. The continuing development of picosecond spectroscopy has made possible the detection and measurement of the primary events in many physical and tiological processes. This article describes a currently used picosecond spectroscopy system that is capable of reliably recording picosecond events. Two areas of picosecond research are discussed; one concerns the interaction of electrons in fluids, and the second the primary events in vision.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Rentzepis, P M -- New York, N.Y. -- Science. 1978 Oct 13;202(4364):174-82.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/694523" target="_blank"〉PubMed〈/a〉
    Keywords: Chemical Phenomena ; Chemistry ; Electrons ; *Kinetics ; Lasers ; Protons ; *Retinal Pigments ; *Rhodopsin ; Spectrum Analysis/*methods ; Temperature ; *Vision, Ocular
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
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  • 2
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    Benzo(a)pyrene-7,8-dihydrodiol 9,10-oxide adenosine and deoxyadenosine adducts: structure and stereochemistry (1979)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1979-12-14
    Description: The structure and absolute stereoconfigurations of four adenosine adducts with (+/-)-7 alpha,8 beta-dihydroxy-9 beta, 10 beta-epoxy-7,8,9,10-tetrahydrobenzo(a)pyrene (BPDE) and their deoxyadenosine analogs have been determined. They result from both cis and trans addition of the N6 amino group of ademine to the 10 position of both enantiomers of BDPE. This was determined from studies of the nuclear magnetic resonance spectra, mass spectra, and circular dichroism spectra, as well as from their pKa values and chemical reactivities.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Jeffrey, A M -- Grzeskowiak, K -- Weinstein, I B -- Nakanishi, K -- Roller, P -- Harvey, R G -- New York, N.Y. -- Science. 1979 Dec 14;206(4424):1309-11.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/316186" target="_blank"〉PubMed〈/a〉
    Keywords: *Benzopyrenes ; Chemical Phenomena ; Chemistry ; Circular Dichroism ; Dna ; *Deoxyadenosines/analogs & derivatives ; Magnetic Resonance Spectroscopy ; Mass Spectrometry ; Molecular Conformation ; Mutation ; Stereoisomerism
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  • 3
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    Rational approaches to chemotherapy: antisickling agents (1981)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1981-08-14
    Description: 〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Klotz, I M -- Haney, D N -- King, L C -- New York, N.Y. -- Science. 1981 Aug 14;213(4509):724-31.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/7256275" target="_blank"〉PubMed〈/a〉
    Keywords: Anemia, Sickle Cell/*drug therapy ; Aspirin/analogs & derivatives/therapeutic use ; Chemical Phenomena ; Chemistry ; *Hemoglobin, Sickle ; Humans ; Protein Binding/drug effects ; Protein Conformation ; Salicylates/*therapeutic use ; Solubility ; Structure-Activity Relationship
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    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
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  • 4
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    Alpha-substituted gamma-butyrolactones: new class of anticonvulsant drugs (1982)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1982-09-10
    Description: Alkyl-Substituted gamma-butyrolactones were synthesized and tested for their convulsant and anticonvulsant actions in mice and guinea pigs. The alpha-substituted compounds, alpha, alpha-dimethyl-, and alpha-ethyl-alpha-methyl-gamma-butyrolactone were anticonvulsant compounds with a spectrum of activity similar to that of ethosuximide. In contrast, beta-substituted compounds were convulsant agents similar to picrotoxinin. The alpha-substituted-gama-butyrolactones represent a new class of anticonvulsant drug with experimental and clinical potential.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Klunk, W E -- McKeon, A -- Covey, D F -- Ferrendelli, J A -- GM-07200/GM/NIGMS NIH HHS/ -- GM-24483/GM/NIGMS NIH HHS/ -- NS-14834/NS/NINDS NIH HHS/ -- etc. -- New York, N.Y. -- Science. 1982 Sep 10;217(4564):1040-2.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/6810462" target="_blank"〉PubMed〈/a〉
    Keywords: *4-Butyrolactone/analogs & derivatives/*therapeutic use/toxicity ; Animals ; *Anticonvulsants ; Chemical Phenomena ; Chemistry ; Convulsants ; Drug Evaluation, Preclinical ; Electroencephalography ; Epilepsy, Absence/drug therapy ; Ethosuximide/pharmacology ; *Furans/*therapeutic use ; Guinea Pigs ; Mice ; Structure-Activity Relationship ; Trimethadione/pharmacology
    Print ISSN: 0036-8075
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    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
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  • 5
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    Phase transition and crystal structure of the 37 degrees C form of cholesterol (1983)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1983-05-06
    Description: Crystalline cholesterol undergoes a phase transition a few degrees below human body temperature. The high-temperature form has an unusually complex structure with 16 independent molecules. In the transition two molecules change side chain conformation, four reorient about their long axes, and ten remain unchanged. The transition mechanism implies relatively nonspecific intermolecular interactions, qualitatively consistent with the behavior of cholesterol in biomembranes. The transition preserves a remarkably closely obeyed pseudosymmetry present in the structure.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Hsu, L Y -- Nordman, C E -- GM15259/GM/NIGMS NIH HHS/ -- New York, N.Y. -- Science. 1983 May 6;220(4597):604-6.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/6836303" target="_blank"〉PubMed〈/a〉
    Keywords: Body Temperature ; Chemical Phenomena ; Chemistry ; *Cholesterol ; Crystallization ; Humans ; Magnetic Resonance Spectroscopy ; Molecular Conformation
    Print ISSN: 0036-8075
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    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
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  • 6
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    Cytochrome a3 structure in carbon monoxide-bound cytochrome oxidase (1984)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1984-07-20
    Description: The iron-carbon monoxide stretching mode and the iron-carbon-oxygen bending mode in carbon monoxide-bound cytochrome oxidase have been assigned at 520 and 578 cm-1, respectively. The frequencies, widths, and intensities of these modes show that the Fe-C-O grouping in carbon monoxide-cytochrome a3 is linear but tilted from the normal to the heme plane; that the iron-histidine bond in both five- and six-coordinate cytochrome a3 is strained; and that the carbon monoxide and the proximal histidine each have characteristic, well-defined orientations in all molecules. These data can account for the binding affinities of carbon monoxide and dioxygen under physiological conditions.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Argade, P V -- Ching, Y C -- Rousseau, D L -- New York, N.Y. -- Science. 1984 Jul 20;225(4659):329-31.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/6330890" target="_blank"〉PubMed〈/a〉
    Keywords: Animals ; Carbon Monoxide/metabolism ; Cattle ; Chemical Phenomena ; Chemistry ; Electron Transport Complex IV/*metabolism ; Myoglobin/metabolism ; Oxidation-Reduction ; Oxygen/metabolism ; Spectrum Analysis, Raman
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  • 7
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    Leukotrienes: mediators of immediate hypersensitivity reactions and inflammation (1983)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1983-05-06
    Description: Arachidonic acid plays a central role in a biological control system where such oxygenated derivatives as prostaglandins, thromboxanes, and leukotrienes are mediators. The leukotrienes are formed by transformation of arachidonic acid into an unstable epoxide intermediate, leukotriene A4, which can be converted enzymatically by hydration to leukotriene B4, and by addition of glutathione to leukotriene C4. This last compound is metabolized to leukotrienes D4 and E4 by successive elimination of a gamma-glutamyl residue and glycine. Slow-reacting substance of anaphylaxis consists of leukotrienes C4, D4, and E4. The cysteinyl-containing leukotrienes are potent bronchoconstrictors, increase vascular permeability in postcapillary venules, and stimulate mucus secretion. Leukotriene B4 causes adhesion and chemotactic movement of leukocytes and stimulates aggregation, enzyme release, and generation of superoxide in neutrophils. Leukotrienes C4, D4, and E4, which are released from the lung tissue of asthmatic subjects exposed to specific allergens, seem to play a pathophysiological role in immediate hypersensitivity reactions. These leukotrienes, as well as leukotriene B4, have pro-inflammatory effects.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Samuelsson, B -- New York, N.Y. -- Science. 1983 May 6;220(4597):568-75.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/6301011" target="_blank"〉PubMed〈/a〉
    Keywords: Animals ; Arachidonic Acids/metabolism/pharmacology/physiology ; Bronchi/drug effects ; Cats ; Chemical Phenomena ; Chemistry ; Cricetinae ; Guinea Pigs ; Haplorhini ; Humans ; Hypersensitivity, Immediate/*physiopathology ; Inflammation/*physiopathology ; Leukocytes/drug effects/metabolism ; Leukotriene B4/pharmacology/*physiology ; Mice ; Microcirculation/drug effects ; Rabbits ; Rats ; SRS-A/*physiology
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  • 8
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    Amphiphilic secondary structure: design of peptide hormones (1984)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1984-01-20
    Description: Peptide synthesis can be used for elucidating the roles of secondary structures in the specificity of hormones, antigens, and toxins. Intermediate sized peptides with these activities assume amphiphilic secondary structures in the presence of membranes. When models are designed to optimize the amphiphilicity of the secondary structure, stronger interactions can be observed with the synthetic peptides than with the naturally occurring analogs.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Kaiser, E T -- Kezdy, F J -- HL-18577/HL/NHLBI NIH HHS/ -- New York, N.Y. -- Science. 1984 Jan 20;223(4633):249-55.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/6322295" target="_blank"〉PubMed〈/a〉
    Keywords: Amino Acid Sequence ; Apolipoprotein A-I ; Apolipoproteins ; Binding Sites ; Calcitonin ; Chemical Phenomena ; Chemistry ; Corticotropin-Releasing Hormone ; Endorphins ; Glucagon ; Growth Hormone-Releasing Hormone ; *Hormones/pharmacology ; Lipoproteins, HDL ; Melitten ; Models, Structural ; *Peptides/chemical synthesis/metabolism/pharmacology ; Protein Conformation ; Structure-Activity Relationship ; beta-Endorphin
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  • 9
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    Fourier transform mass spectrometry (1984)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1984-10-19
    Description: Fourier transform mass spectrometry will play an important role in the future because of its unique combination of high mass resolution, high upper mass limit, and multichannel advantage. These features have already found application in gas chromatography-mass spectrometry, multiphoton ionization, laser desorption, and secondary ion mass spectrometry. However, its most notable feature is the ability to store ions. This characteristic, when combined with the others, will allow expeditious study of the interaction of gas-phase ions with both photons (photodissociation) and neutral molecules, and the convenient application of this fundamental information for chemical analysis.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Gross, M L -- Rempel, D L -- 2-8423576/PHS HHS/ -- New York, N.Y. -- Science. 1984 Oct 19;226(4672):261-8.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/6385250" target="_blank"〉PubMed〈/a〉
    Keywords: Chemical Phenomena ; Chemistry ; *Fourier Analysis ; Ions ; Lasers ; *Mass Spectrometry/instrumentation/methods
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  • 10
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    Studying enzyme mechanism by 13C nuclear magnetic resonance (1984)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1984-08-31
    Description: High-resolution carbon-13 nuclear magnetic resonance (NMR) spectra of enzyme-inhibitor and enzyme-substrate complexes provide detailed structural and stereochemical information on the mechanism of enzyme action. The proteases trypsin and papain are shown to form tetrahedrally coordinated complexes and acyl derivatives with a variety of compounds artificially enriched at the site or sites of interest. These results are compared with the structural information derived from x-ray diffraction. Detailed NMR studies have provided a clearer picture of the ionization state of the residues participating in enzyme-catalyzed processes than other more classical techniques. The dynamics of enzymic catalysis can be observed at sub-zero temperatures by a combination of cryoenzymology and carbon-13 NMR spectroscopy. With these powerful techniques, transient, covalently bound intermediates in enzyme-catalyzed reactions can be detected and their structures rigorously assigned.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Mackenzie, N E -- Malthouse, J P -- Scott, A I -- New York, N.Y. -- Science. 1984 Aug 31;225(4665):883-9.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/6433481" target="_blank"〉PubMed〈/a〉
    Keywords: Binding Sites ; Carbon Isotopes ; Carboxypeptidases/metabolism ; Carboxypeptidases A ; Catalysis ; Chemical Phenomena ; Chemistry ; Coenzymes/*metabolism ; Endopeptidases/metabolism ; Enzymes/*metabolism ; Freezing ; Fructose-Bisphosphate Aldolase/metabolism ; Magnetic Resonance Spectroscopy ; Papain/metabolism ; Pepsin A/metabolism ; Peptide Hydrolases/*metabolism ; Protease Inhibitors ; Pterins/metabolism ; Pyridoxal Phosphate/metabolism ; Serine Endopeptidases
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  • 11
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    What is the risk from chlorofluorocarbons? (1984)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1984-03-09
    Description: 〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Maugh, T H 2nd -- New York, N.Y. -- Science. 1984 Mar 9;223(4640):1051-2.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/6695193" target="_blank"〉PubMed〈/a〉
    Keywords: *Air Pollutants ; *Atmosphere ; Carbon Tetrachloride ; Chemical Phenomena ; Chemistry ; *Chlorofluorocarbons, Methane ; Free Radicals ; Nitrogen Dioxide ; Nitrous Oxide ; Oxygen ; *Ozone ; Photochemistry ; Risk ; Singlet Oxygen ; Trichloroethanes ; Ultraviolet Rays
    Print ISSN: 0036-8075
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  • 12
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    Pyrolysis mass spectrometry of complex organic materials (1984)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1984-10-19
    Description: Pyrolysis mass spectrometry in combination with computerized multivariate statistical analysis enables qualitative and quantitative analysis of nonvolatile organic materials containing molecular assemblies of a complexity and size far beyond the capabilities of direct mass spectrometry. The state of the art in pyrolysis mass spectrometry techniques is illustrated through specific applications, including structural determination and quality control of synthetic polymers, quantitative analysis of polymer mixtures, classification and structural characterization of fossil organic matter, and nonsupervised numerical extraction of component patterns from complex biological samples.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Meuzelaar, H L -- Windig, W -- Harper, A M -- Huff, S M -- McClennen, W H -- Richards, J M -- New York, N.Y. -- Science. 1984 Oct 19;226(4672):268-74.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/6484572" target="_blank"〉PubMed〈/a〉
    Keywords: Biochemical Phenomena ; Biochemistry ; Chemical Phenomena ; Chemistry ; Coal ; Enterobacteriaceae/analysis/isolation & purification ; Hot Temperature ; Mass Spectrometry/*methods ; Polymers
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  • 13
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    Lariat RNA's as intermediates and products in the splicing of messenger RNA precursors (1984)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1984-08-31
    Description: The splicing of messenger RNA precursors in vitro proceeds through an intermediate that has the 5' end of the intervening sequence joined to a site near the 3' splice site. This lariat structure, which has been characterized for an adenovirus 2 major late transcript, has a branch point, with 2'-5' and 3'-5' phosphodiester bonds emanating from a single adenosine residue. The excised intervening sequence retains the branch site and terminates in a guanosine residue with a 3' hydroxyl group. The phosphate group at the splice junction between the two exons originates from the 3' splice site at the precursor.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Padgett, R A -- Konarska, M M -- Grabowski, P J -- Hardy, S F -- Sharp, P A -- P01-CA14051/CA/NCI NIH HHS/ -- P01-CA26717/CA/NCI NIH HHS/ -- R01-GM32467/GM/NIGMS NIH HHS/ -- New York, N.Y. -- Science. 1984 Aug 31;225(4665):898-903.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/6206566" target="_blank"〉PubMed〈/a〉
    Keywords: Adenoviruses, Human/metabolism ; Base Sequence ; Chemical Phenomena ; Chemistry ; Nucleic Acid Conformation ; Nucleic Acid Precursors/analysis/*metabolism ; Oligoribonucleotides/metabolism ; Phosphates/metabolism ; RNA/analysis/*metabolism ; RNA Precursors ; *RNA Splicing ; RNA, Messenger/analysis/*metabolism ; RNA, Viral/analysis/*metabolism
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  • 14
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    beta-Carotene: an unusual type of lipid antioxidant (1984)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1984-05-11
    Description: The mechanism of lipid peroxidation and the manner in which antioxidants function is reviewed. beta-Carotene is a purported anticancer agent, which is believed by some to have antioxidant action of a radical-trapping type. However, definitive experimental support for such action has been lacking. New experiments in vitro show that beta-carotene belongs to a previously unknown class of biological antioxidants. Specifically, it exhibits good radical-trapping antioxidant behavior only at partial pressures of oxygen significantly less than 150 torr, the pressure of oxygen in normal air. Such low oxygen partial pressures are found in most tissues under physiological conditions. At higher oxygen pressures, beta-carotene loses its antioxidant activity and shows an autocatalytic, prooxidant effect, particularly at relatively high concentrations. Similar oxygen-pressure-dependent behavior may be shown by other compounds containing many conjugated double bonds.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Burton, G W -- Ingold, K U -- New York, N.Y. -- Science. 1984 May 11;224(4649):569-73.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/6710156" target="_blank"〉PubMed〈/a〉
    Keywords: Antioxidants/*metabolism ; Carotenoids/*metabolism ; Chemical Phenomena ; Chemistry ; Free Radicals ; Humans ; Linoleic Acids/metabolism ; *Lipid Metabolism ; Oxidation-Reduction ; Oxygen/metabolism ; Partial Pressure ; Peroxides/metabolism ; Tetrahydronaphthalenes/metabolism ; beta Carotene
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  • 15
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    Bromine residue at hydrophilic region influences biological activity of aplysiatoxin, a tumor promoter (1983)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1983-12-16
    Description: Aplysiatoxin and debromoaplysiatoxin, which are isolated from the seaweed, Lyngbya gracilis, differ in their chemical structure only by the presence or absence of a bromine residue in the hydrophilic region. The function and the structure-activity relation of the hydrophilic region are not known. Aplysiatoxin increased malignant transformation, stimulated DNA synthesis, and inhibited the binding of phorbol-12,13-dibutyrate and epidermal growth factor to cell receptors. Debromoaplysiatoxin inhibited the binding of these two substances as strongly as aplysiatoxin but did not increase malignant transformation or stimulate DNA synthesis. These results indicate that a slight change in the chemical structure of the hydrophilic region of aplysiatoxin affects its abilities to increase cell transformation and stimulate DNA synthesis and that the abilities of the tumor promoters to inhibit the binding of phorbol-12,13-dibutyrate and epidermal growth factor are dissociable from their abilities to increase cell transformation and stimulate DNA synthesis under some circumstances.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Shimomura, K -- Mullinix, M G -- Kakunaga, T -- Fujiki, H -- Sugimura, T -- New York, N.Y. -- Science. 1983 Dec 16;222(4629):1242-4.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/6316505" target="_blank"〉PubMed〈/a〉
    Keywords: Animals ; *Caenorhabditis elegans Proteins ; Carcinogens/*pharmacology ; Carrier Proteins ; Cell Line ; Cell Transformation, Neoplastic/*drug effects ; Chemical Phenomena ; Chemistry ; DNA/biosynthesis ; Epidermal Growth Factor/metabolism ; Lactones/analysis/*pharmacology ; *Lyngbya Toxins ; Mice ; Phorbol 12,13-Dibutyrate ; Phorbol Esters/metabolism ; *Protein Kinase C ; Receptor, Epidermal Growth Factor ; Receptors, Cell Surface/metabolism ; *Receptors, Drug ; Structure-Activity Relationship
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  • 16
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    Phenylalanine transfer RNA: molecular dynamics simulation (1984)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1984-03-16
    Description: Yeast phenylalanine transfer RNA was subjected to a 12-picosecond molecular dynamics simulation. The principal features of the x-ray crystallographic analysis are reproduced, and the amplitudes of atomic displacements appear to be determined by the degree of exposure of the atoms. An analysis of the hydrogen bonds shows a correlation between the average length of a bond and the fluctuation in that length and reveals a rocking motion of bases in Watson-Crick guanine X cytosine base pairs. The in-plane motions of the bases are generally of larger amplitude than the out-of-plane motions, and there are correlations in the motions of adjacent bases.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Harvey, S C -- Prabhakaran, M -- Mao, B -- McCammon, J A -- New York, N.Y. -- Science. 1984 Mar 16;223(4641):1189-91.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/6560785" target="_blank"〉PubMed〈/a〉
    Keywords: Chemical Phenomena ; Chemistry ; Computers ; Cytosine ; Guanine ; Hydrogen Bonding ; Nucleic Acid Conformation ; *RNA, Fungal ; *RNA, Transfer, Amino Acyl ; Yeasts/analysis
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  • 17
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    Reaction of the antitumor antibiotic CC-1065 with DNA: structure of a DNA adduct with DNA sequence specificity (1984)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1984-11-16
    Description: Sequence-dependent variations in DNA revealed by x-ray crystallographic studies have suggested that certain DNA-reactive drugs may react preferentially with defined sequences in DNA. Drugs that wind around the helix and reside within one of the grooves of DNA have perhaps the greatest chance of recognizing sequence-dependent features of DNA. The antitumor antibiotic CC-1065 covalently binds through N-3 of adenine and resides within the minor groove of DNA. This drug overlaps with five base pairs for which a high sequence specificity exists.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Hurley, L H -- Reynolds, V L -- Swenson, D H -- Petzold, G L -- Scahill, T A -- New York, N.Y. -- Science. 1984 Nov 16;226(4676):843-4.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/6494915" target="_blank"〉PubMed〈/a〉
    Keywords: Antibiotics, Antineoplastic/*metabolism ; *Base Sequence ; Binding Sites ; Chemical Phenomena ; Chemistry ; DNA/*metabolism ; *Indoles ; Leucomycins/*metabolism ; Molecular Conformation ; X-Ray Diffraction
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  • 18
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    Allylamine derivatives: new class of synthetic antifungal agents inhibiting fungal squalene epoxidase (1984)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1984-06-15
    Description: A new class of synthetic antifungal agents, the allylamines , has been developed by modification of naftifine , a topical antimycotic. SF 86-327, the most effective of these compounds so far, is highly active in vitro against a wide range of fungi and exceeds clinical standards in the oral and topical treatment of guinea pig dermatophytoses. SF 86-327 is a powerful specific inhibitor of fungal squalene epoxidase, a key enzyme in sterol biosynthesis.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Petranyi, G -- Ryder, N S -- Stutz, A -- New York, N.Y. -- Science. 1984 Jun 15;224(4654):1239-41.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/6547247" target="_blank"〉PubMed〈/a〉
    Keywords: Allylamine/analogs & derivatives/*chemical synthesis/pharmacology ; Amines/*chemical synthesis ; Animals ; Antifungal Agents/*chemical synthesis/pharmacology ; Chemical Phenomena ; Chemistry ; Dermatomycoses/drug therapy ; Fungi/*drug effects/enzymology ; Guinea Pigs ; Naphthalenes/chemical synthesis/pharmacology ; Oxygenases/*antagonists & inhibitors ; Squalene Monooxygenase
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    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
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  • 19
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    Disulfide bond engineered into T4 lysozyme: stabilization of the protein toward thermal inactivation (1984)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1984-11-02
    Description: By recombinant DNA techniques, a disulfide bond was introduced at a specific site in T4 lysozyme, a disulfide-free enzyme. This derivative retained full enzymatic activity and was more stable toward thermal inactivation than the wild-type protein. The derivative, T4 lysozyme (Ile3----Cys), was prepared by substituting a Cys codon for an Ile codon at position 3 in the cloned lysozyme gene by means of oligonucleotide-dependent, site-directed mutagenesis. The new gene was expressed in Escherichia coli under control of the (trp-lac) hybrid tac promoter, and the protein was purified. Mild oxidation generated a disulfide bond between the new Cys3 and Cys97, one of the two unpaired cysteines of the native molecule. Oxidized T4 lysozyme (Ile3----Cys) exhibited specific activity identical to that of the wild-type enzyme when measured at 20 degrees C in a cell-clearing assay. The cross-linked protein was more stable than the wild type during incubation at elevated temperatures as determined by recovered enzymatic activity at 20 degrees C.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Perry, L J -- Wetzel, R -- New York, N.Y. -- Science. 1984 Nov 2;226(4674):555-7.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/6387910" target="_blank"〉PubMed〈/a〉
    Keywords: Chemical Phenomena ; Chemistry ; DNA, Recombinant/metabolism ; Escherichia coli/enzymology ; *Genetic Engineering ; Kinetics ; Muramidase/*genetics/metabolism ; Protein Denaturation
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  • 20
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    DNA-binding proteins (1983)
    American Association for the Advancement of Science (AAAS)
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    Publication Date: 1983-09-09
    Description: The structures of three proteins that regulate gene expression have been determined recently and suggest how these proteins may bind to their specific recognition sites on the DNA. One protein (Cro) is a repressor of gene expression, the second (CAP) usually stimulates gene expression, and the third (lambda repressor) can act as either a repressor or an activator. The three proteins contain a substructure consisting of two consecutive alpha helices that is virtually identical in each case. Structural and amino acid sequence comparisons suggest that this bihelical fold occurs in a number of proteins that regulate gene expression, and is an intrinsic part of the DNA-protein recognition event. The modes of repression and activation by Cro and lambda repressor are understood reasonably well, but the mode of action of CAP is still unclear.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Takeda, Y -- Ohlendorf, D H -- Anderson, W F -- Matthews, B W -- GM20066/GM/NIGMS NIH HHS/ -- GM28138/GM/NIGMS NIH HHS/ -- GM30894/GM/NIGMS NIH HHS/ -- New York, N.Y. -- Science. 1983 Sep 9;221(4615):1020-6.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/6308768" target="_blank"〉PubMed〈/a〉
    Keywords: Amino Acid Sequence ; Chemical Phenomena ; Chemistry ; *DNA Helicases ; DNA-Binding Proteins ; Escherichia coli/genetics ; Gene Expression Regulation ; Models, Chemical ; Protein Conformation
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  • 21
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    A nitrogen pressure of 50 atmospheres does not prevent evolution of hydrogen by nitrogenase (1984)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1984-06-08
    Description: The effect of a partial pressure of nitrogen of 50 atmospheres (5065 kilopascals ) on the hydrogen evolution reaction of nitrogenase has been investigated. Evolution of hydrogen was not blocked completely by 50 atmospheres of nitrogen in any of four experiments; rather, 27.3 +/- 2.4 percent of the total electron flux through nitrogenase was directed toward production of hydrogen. The ratio of hydrogen evolved to nitrogen fixed was close to 1:1, which implies that hydrogen evolution is obligatory in the fixation of molecular nitrogen by nitrogenase.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Simpson, F B -- Burris, R H -- AI-00848/AI/NIAID NIH HHS/ -- New York, N.Y. -- Science. 1984 Jun 8;224(4653):1095-7.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/6585956" target="_blank"〉PubMed〈/a〉
    Keywords: Chemical Phenomena ; Chemistry ; *Hydrogen ; *Nitrogen ; Nitrogen Fixation ; *Nitrogenase ; Partial Pressure
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    Foreign aid support of science and economic growth (1978)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1978-03-17
    Description: The history of U.S. foreign aid support of science and technology in Latin America is examined and an attempt is made to evaluate the scientific and economic growth of that area in relation to the total foreign aid effort.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Szmant, H H -- New York, N.Y. -- Science. 1978 Mar 17;199(4334):1173-82.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/415363" target="_blank"〉PubMed〈/a〉
    Keywords: Chemistry ; Cost-Benefit Analysis ; Education ; History, 20th Century ; International Educational Exchange ; Latin America ; *Research Support as Topic ; *Science/history ; United States
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    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
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  • 23
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    Nonvolatile mutagens in drinking water: production by chlorination and destruction by sulfite (1980)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1980-01-04
    Description: In concentrates of water produced in a laboratory simulation of a drinking water treatment process, direct-acting, nonvolatile mutagens were readily detected by means of the Ames Salmonella test. The mutagens were shown to be produced by the chlorination process. Treatment of the water with chloramine resulted in less mutagenic activity than treatment with free chlorine. Dechlorination of drinking water with sulfite sharply reduced the mutagenic activity. Treatment with sulfur dioxide is proposed as an effective, inexpensive method of reducing the direct-acting mutagenic activity of drinking water and of aqueous industrial effluents.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Cheh, A M -- Skochdopole, J -- Koski, P -- Cole, L -- New York, N.Y. -- Science. 1980 Jan 4;207(4426):90-2.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/6985746" target="_blank"〉PubMed〈/a〉
    Keywords: Chemical Phenomena ; Chemistry ; Chloramines ; Chlorine ; Mutagens/*analysis ; Salmonella typhimurium/genetics ; Sulfites ; Water Pollutants/*analysis ; Water Pollutants, Chemical/*analysis ; Water Supply/*analysis
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    Automated synthesis of gene fragments (1981)
    American Association for the Advancement of Science (AAAS)
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    Publication Date: 1981-10-16
    Description: The DNA/RNA Synthesizer provides a complete and automated procedure for the synthesis of DNA sequences. Each base unit is added in a 30-minute cycle, permitting a tetradecamer to be constructed in 6 1/2 hours. The complete procedure is described, including a practical procedure for isolation and purification of the desired DNA sequence.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Alvarado-Urbina, G -- Sathe, G M -- Liu, W C -- Gillen, M F -- Duck, P D -- Bender, R -- Ogilvie, K K -- New York, N.Y. -- Science. 1981 Oct 16;214(4518):270-4.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/6169150" target="_blank"〉PubMed〈/a〉
    Keywords: Automation ; Chemical Phenomena ; Chemistry ; DNA/*chemical synthesis ; *Genes, Synthetic ; RNA/*chemical synthesis ; Solubility
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    Chitin: New facets of research (1981)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1981-05-15
    Description: Research on chitin as a marine resource is pointing to novel applications for this cellulose-like biopolymer. Discovery of nondegrading solvent systems has permitted the spinning of filaments, for example, for use as surgical sutures. New methods for preparing the bioactive alkyl glycoside of N-acetyl-D-glucosamine (the monomer unit of chitin) and a microcrystalline chitin has encouraged their use as promoters for growth of bifidobacteria and as an aid in digestion of high-lactose cheese whey by domestic animals. Chitin-protein complexes of several crustacean species show great variability in ratios of chitin to covalently bound protein and in residual protein in the "purified" chitins.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Austin, P R -- Brine, C J -- Castle, J E -- Zikakis, J P -- New York, N.Y. -- Science. 1981 May 15;212(4496):749-53.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/7221561" target="_blank"〉PubMed〈/a〉
    Keywords: Animal Feed ; Animals ; Cheese ; Chemical Phenomena ; Chemistry ; Chickens ; *Chitin ; Crystallography ; Lactose/metabolism ; Proteins/analysis ; Sutures ; *Technology
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    DNA sequencing and gene structure (1981)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1981-12-18
    Description: 〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Gilbert, W -- New York, N.Y. -- Science. 1981 Dec 18;214(4527):1305-12.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/7313687" target="_blank"〉PubMed〈/a〉
    Keywords: Base Sequence ; Chemical Phenomena ; Chemistry ; DNA/*genetics ; Eukaryotic Cells/physiology ; *Genes ; Hydrazines ; Lac Operon ; Methylation ; Prokaryotic Cells/physiology ; Sulfuric Acid Esters
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  • 27
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    Boradeption: a new procedure for transferring water-insoluble agents across cell membranes (1982)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1982-07-09
    Description: A new process has been developed which is called "Boradeption" to signify boronic acid--dependent phase transfer of water-insoluble agents. Highly fluorescent boronic acid dervatives, FluoroBoras, are solubilized with a physiologically compatible carrier buffer containing a receptor group for boronate adduct formation. The system can be used to stain living cells. In another variation of the Boradeption concept, an insoluble reporter molecule containing a boronate receptor is solubilized with a carrier buffer containing a boronic acid functional group. The boronate-receptor complexes, which are in dynamic equilibrium, can be designed as vital stains and reagents for a variety of biological and medical applications.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Gallop, P M -- Paz, M A -- Henson, E -- AG-00376-07/AG/NIA NIH HHS/ -- HL-20764-04A1/HL/NHLBI NIH HHS/ -- New York, N.Y. -- Science. 1982 Jul 9;217(4555):166-9.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/6178158" target="_blank"〉PubMed〈/a〉
    Keywords: Animals ; *Biological Transport ; *Boron Compounds/therapeutic use ; *Boronic Acids/therapeutic use ; *Cell Membrane Permeability ; Cells, Cultured ; Chemical Phenomena ; Chemistry ; Chromogenic Compounds/metabolism ; Cricetinae ; Fibroblasts ; Fluorescent Dyes/metabolism ; Humans ; Rats ; Staining and Labeling
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    Reversible chemical modification of the scrapie agent (1981)
    American Association for the Advancement of Science (AAAS)
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    Publication Date: 1981-12-11
    Description: The scrapie agent causes a degenerative nervous system disease in sheep and goats. Studies with extensively purified preparations demonstrated that the agent contains a protein that is required for infectivity. Chemical modification of the scrapie agent by diethyl pyrocarbonate reduced the titer 1000-fold. Exposure of the inactivated agent to hydroxylamine, a strong nucleophile, resulted in complete restoration of infectivity. Presumably, nucleophilic residues within a scrapie agent protein undergo carbethoxylation on reaction with diethyl pyrocarbonate, and subsequent addition of hydroxylamine displaces these carbethoxy groups.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉McKinley, M P -- Masiarz, F R -- Prusiner, S B -- NS14069/NS/NINDS NIH HHS/ -- New York, N.Y. -- Science. 1981 Dec 11;214(4526):1259-61.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/6795721" target="_blank"〉PubMed〈/a〉
    Keywords: Animals ; Biological Assay ; Brain/microbiology ; Chemical Phenomena ; Chemistry ; Cricetinae ; Diethyl Pyrocarbonate/pharmacology ; Histidine/pharmacology ; *Prions ; Ribonucleases/pharmacology ; Serum Albumin, Bovine/pharmacology ; Viral Proteins/*isolation & purification/pharmacology
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  • 29
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    Nonenzymatic browning in vivo: possible process for aging of long-lived proteins (1981)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1981-01-30
    Description: The incubation of lens proteins with reducing sugars leads to the formation of fluorescent yellow pigments and cross-like similar to those reported in aging and cataractous human lenses. Called nonenzymatic browning or the Maillard reaction, this aging process also occurs in stored foods. Reducing sugars condense with the free amino group of proteins, then rearrange and dehydrate to form unsaturated pigments and cross-linked products. Although most proteins in living systems turn over with sufficient rapidity to avoid nonenzymatic browning, some, such as lens crystallins and skin collagen, are exceptionally long-lived and may be vulnerable.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Monnier, V M -- Cerami, A -- AM 19655/AM/NIADDK NIH HHS/ -- New York, N.Y. -- Science. 1981 Jan 30;211(4481):491-3.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/6779377" target="_blank"〉PubMed〈/a〉
    Keywords: *Aging ; Animals ; Cattle ; Chemical Phenomena ; Chemistry ; *Crystallins ; Diabetes Mellitus/physiopathology ; Glucose ; Glucosephosphates ; In Vitro Techniques ; Lysine ; *Proteins ; Spectrophotometry, Ultraviolet
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    The National Science Foundation looks to the future (1981)
    American Association for the Advancement of Science (AAAS)
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    Publication Date: 1981-03-13
    Description: Great advances have been made in fundamental scientific research in recent years. The new knowledge gathered, in addition to deepening our understanding of the physical universe, contributes a range of abilities and opportunities to society that would not otherwise be available. Much research that may be called applied because it addresses needs of society is quite fundamental in character, and support of such research at the National Science Foundation is to be handled in tandem by the research directorates. Other areas that require a refocusing of support are engineering science and education, at all levels, in science and engineering. Increasing our strength in these areas is essential to achieve our national economic, social, and political goals. Steps are being taken by the National Science Foundation to make its structure better able to deal with engineering and applied research and to provide greater mutual reinforcement between applied and basic research.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Slaughter, J B -- New York, N.Y. -- Science. 1981 Mar 13;211(4487):1131-6.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/7466384" target="_blank"〉PubMed〈/a〉
    Keywords: Cell Biology ; Chemical Phenomena ; Chemistry ; *Forecasting ; Geological Phenomena ; Geology ; *Government Agencies ; Molecular Biology ; Neurochemistry ; Physical Phenomena ; Physics ; Research Support as Topic ; United States
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    New chemistry of an old molecule: cis-[Pt(NH3)2Cl2] (1982)
    American Association for the Advancement of Science (AAAS)
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    Publication Date: 1982-12-10
    Description: The discovery that cis-diamminedichloroplatinum(II) (cis-DDP) has clinically useful antitumor properties and can form platinum blues spawned an extensive investigation of its chemistry in water. Several new molecules have been synthesized, some rather old ones have been characterized for the first time, and clues have begun to emerge about the chemical interaction of cis-DDP with its likely biological target, DNA.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Lippard, S J -- New York, N.Y. -- Science. 1982 Dec 10;218(4577):1075-82.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/6890712" target="_blank"〉PubMed〈/a〉
    Keywords: Chemical Phenomena ; Chemistry ; *Cisplatin ; *Dna ; Hydrolysis ; Pigments, Biological
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  • 32
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    The chemistry of vision (1982)
    American Association for the Advancement of Science (AAAS)
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    Publication Date: 1982-12-03
    Description: The visual response is initiated by light reception and transduction into chemical and electrical energy in the outer-segment membranes of rod and cone cells. Recent research on the molecular events controlled by light has clarified the roles of some of the rod outer-segment biomolecules. These developments and the current unresolved questions are described.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉O'Brien, D F -- New York, N.Y. -- Science. 1982 Dec 3;218(4576):961-6.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/6291153" target="_blank"〉PubMed〈/a〉
    Keywords: Animals ; Blood Proteins/metabolism ; Calcium/metabolism ; Chemical Phenomena ; Chemistry ; Enzyme Activation ; Enzymes/metabolism ; GTP-Binding Proteins ; Light ; Membranes/metabolism ; Models, Biological ; Phosphoric Diester Hydrolases/biosynthesis ; Photoreceptor Cells/*metabolism ; Receptors, Cell Surface/metabolism ; Rhodopsin/metabolism ; Rod Cell Outer Segment/*metabolism ; Vision, Ocular/*physiology
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    Antiviral agents (1983)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1983-06-10
    Description: 〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Krenitsky, T A -- Beauchamp, L -- New York, N.Y. -- Science. 1983 Jun 10;220(4602):1106.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/6857236" target="_blank"〉PubMed〈/a〉
    Keywords: Acyclovir/metabolism ; *Antiviral Agents/metabolism ; Chemical Phenomena ; Chemistry ; Humans ; Vidarabine/metabolism
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
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    Metastable species of hemoglobin: room temperature transients and cryogenically trapped intermediates (1983)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1983-05-06
    Description: Resonance Raman spectra of photolyzed carbonmonoxyhemoglobin obtained with 10-nanosecond pulses are compared with the spectra of photolyzed carbonmonoxyhemoglobin stabilized at 80 K. In comparing the deoxy with the photodissociated species, the changes in the Raman spectra are the same for these two experimental regimes. These results show that at ambient and cryogenic temperatures the heme pocket in liganded hemoglobin is significantly different from that of deoxyhemoglobin. It is concluded that measurements of the properties of intermediate species from photodissociated hemoglobin stabilized at low temperatures can be used to probe the short-lived metastable forms of hemoglobin present after photodissociation under biologically relevant solution conditions.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Ondrias, M R -- Friedman, J M -- Rousseau, D L -- New York, N.Y. -- Science. 1983 May 6;220(4597):615-7.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/6836305" target="_blank"〉PubMed〈/a〉
    Keywords: Carboxyhemoglobin ; Chemical Phenomena ; Chemistry ; Freezing ; *Hemoglobins ; Humans ; Ligands ; Spectrum Analysis, Raman ; Temperature
    Print ISSN: 0036-8075
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    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
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  • 35
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    Irreversible ligands with high selectivity toward delta and mu opiate receptors (1983)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1983-04-15
    Description: Alkylating agents that display strong selectivity for opiate receptor types delta or mu were prepared by appropriate modification of the structures of the strong analgesics fentanyl, etonitazene, and endoethenotetrahydrooripavine. The availability of these substances should facilitate studies of the structural basis of receptor specificity and of the physiologic roles of these receptors.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Rice, K C -- Jacobson, A E -- Burke, T R Jr -- Bajwa, B S -- Streaty, R A -- Klee, W A -- New York, N.Y. -- Science. 1983 Apr 15;220(4594):314-6.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/6132444" target="_blank"〉PubMed〈/a〉
    Keywords: Alkylation ; Animals ; Benzimidazoles/analogs & derivatives/metabolism ; Brain/physiology ; Cells, Cultured ; Chemical Phenomena ; Chemistry ; Enkephalin, Methionine/analogs & derivatives/metabolism ; Fentanyl/analogs & derivatives/metabolism ; *Isothiocyanates ; Ligands ; Rats ; Receptors, Opioid/*metabolism/physiology ; Thebaine/analogs & derivatives/pharmacology
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
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  • 36
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    The glycosylation of hemoglobin: relevance to diabetes mellitus (1978)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1978-04-07
    Description: Glucose reacts nonenzymatically with the NH2-terminal amino acid of the beta chain of human hemoglobin by way of a ketoamine linkage, resulting in the formation of hemoglobin AIc. Other minor components appear to be adducts of glucose 6-phosphate and fructose 1,6-diphosphate. These hemoglobins are formed slowly and continuously throughout the 120-day life-span of the red cell. There is a two- to threefold increase in hemoglobin AIc in the red cells of patients with diabetes mellitus. By providing an integrated measurement of blood glucose, hemoglobin AIc is useful in assessing the degree of diabetic control. Furthermore, this hemoglobin is a useful model of nonenzymatic glycosylation of other proteins that may be involved in the long-term complications of the disease.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Bunn, H F -- Gabbay, K H -- Gallop, P M -- New York, N.Y. -- Science. 1978 Apr 7;200(4337):21-7.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/635569" target="_blank"〉PubMed〈/a〉
    Keywords: Blood Glucose/metabolism ; Chemical Phenomena ; Chemistry ; Diabetes Complications ; Diabetes Mellitus/*blood/diagnosis ; Diphosphoglyceric Acids/blood ; Glycosides/blood ; Glycosuria/etiology ; Hemoglobin A/*metabolism ; Hemoglobins/*analysis/*metabolism ; Humans ; Kinetics ; Oxygen/blood ; Structure-Activity Relationship
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    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
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  • 37
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    N-formyliminodiacetic acid, a new compound from the reaction of nitrilotriacetic acid and chlorine (1979)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1979-06-08
    Description: It has been proposed that nitrilotriacetic acid be substituted for trisodium polyphosphates in detergents as a way to reduce the rate of eutrophication in the Great Lake Basin. The reaction of nitrilotriacetic acid with chlorine-containing solutions produces a hitherto unknown degradation production, N-formyliminodiacetic acid, in high yield. The toxicological and environmental implications of this reaction are unclear.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Spanggord, R J -- Tyson, C A -- New York, N.Y. -- Science. 1979 Jun 8;204(4397):1081-2.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/36659" target="_blank"〉PubMed〈/a〉
    Keywords: *Acetates ; Chemical Phenomena ; Chemistry ; *Chlorine ; Dicarboxylic Acids ; Environmental Pollutants ; Hydrogen-Ion Concentration ; *Imino Acids ; Mutagens ; *Nitrilotriacetic Acid
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    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
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  • 38
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    HCN did not condense to give heteropolypeptides on the primitive earth (1979)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1979-03-16
    Description: 〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Ferris, J P -- New York, N.Y. -- Science. 1979 Mar 16;203(4385):1135-7.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/218287" target="_blank"〉PubMed〈/a〉
    Keywords: Chemical Phenomena ; Chemistry ; *Hydrogen Cyanide ; *Peptides
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
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  • 39
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    Trace chemistries of fire: a source of chlorinated dioxins (1980)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1980-10-01
    Description: 〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Bumb, R R -- Crummett, W B -- Cutie, S S -- Gledhill, J R -- Hummel, R H -- Kagel, R O -- Lamparski, L L -- Luoma, E V -- Miller, D L -- Nestrick, T J -- Shadoff, L A -- Stehl, R H -- Woods, J S -- New York, N.Y. -- Science. 1980 Oct;210(4468):385-90.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/6159682" target="_blank"〉PubMed〈/a〉
    Keywords: Air Pollutants/analysis ; Chemical Phenomena ; Chemistry ; Chromatography, High Pressure Liquid ; *Dioxins/analysis ; *Fires ; Power Plants ; Smoke/analysis ; Soil Pollutants/analysis ; Tetrachlorodibenzodioxin/analysis ; Vehicle Emissions/analysis ; Water Pollutants, Chemical/analysis
    Print ISSN: 0036-8075
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    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
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  • 40
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    Synthetic competitive antagonists of corticotropin-releasing factor: effect on ACTH secretion in the rat (1984)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1984-05-25
    Description: Polypeptide analogs of the known members of the corticotropin-releasing factor (CRF) family were synthesized and tested in vitro and in vivo for enhanced potency or competitive antagonism. Predictive methods and physicochemical measurements had suggested an internal secondary alpha-helical conformation spanning about 25 residues for at least three members of the CRF family. Maximization of alpha-helix-forming potential by amino acid substitutions from the native known sequences (rat/human and ovine CRF, sauvagine, and carp and sucker urotensin 1) led to the synthesis of an analog that was found to be more than twice as potent as either of the parent peptides in vitro. In contrast, certain amino-terminally shortened fragments, such as alpha-helical CRF or ovine CRF residues 8 to 41, 9 to 41, and 10 to 41, were found to be competitive inhibitors in vitro. Selected antagonists were examined and also found to be active in vivo.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Rivier, J -- Rivier, C -- Vale, W -- AA03504/AA/NIAAA NIH HHS/ -- AM20917/AM/NIADDK NIH HHS/ -- AM26741/AM/NIADDK NIH HHS/ -- etc. -- New York, N.Y. -- Science. 1984 May 25;224(4651):889-91.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/6326264" target="_blank"〉PubMed〈/a〉
    Keywords: Adrenocorticotropic Hormone/secretion ; Animals ; Binding, Competitive ; Chemical Phenomena ; Chemistry ; Corticotropin-Releasing Hormone/*antagonists & inhibitors ; Rats
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    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
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  • 41
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    Curatorial functions and the U.S. Antarctic meteorite program (1981)
    In:  Other Sources
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    Publication Date: 2011-08-24
    Description: The discovery of concentrations of meteorites in Antarctica by Japanese field parties in 1969, and subsequently by joint U.S.-Japanese and U.S. field parties since 1976 has provided a significant new resource for understanding the origin and evolution of the solar system. The number of meteorites as well as the variety of meteorites has increased dramatically, and substantial amounts of data derived from their study has begun to appear in the scientific literature. The U.S. program of investigation has drawn on curatorial experience derived from the lunar program to: (1) develop specific collection and preliminary examination protocols; (2) provide documented samples for scientific investigations in response to specific requests; and (3) coordinate research by scientific consortia. The productivity of scientific research is significantly enhanced by these management approaches. Some of the results of the curatorial program for Antarctic meteorites carried out over the past three years are described.
    Keywords: LUNAR AND PLANETARY EXPLORATION
    Type: National Institute of Polar Research, Memoirs (ISSN 0386-0744); 20, D
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    Some unique meteorites found in Antarctica and their relation to asteroids (1979)
    In:  Other Sources
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    Publication Date: 2011-08-24
    Description: Two unique meteorites were identified by means of a mineralogical examination of the smaller-sized Yamato achondrites. Yamato-74130 is the most iron-rich ureilite with Na, Cr-rich augite instead of pigeonite. Yamato-74160 was extensively recrystallized, but the composition and proportion of olivine, orthopyroxene, augite, and plagioclase is consistent with LL7 chondrites. ALHA77005 is a unique achondrite with olivine, possibly three pyroxene assemblages, and maskelynite. These meteorites provide evidence that there may be other 'thermalized' asteroids than the howardite parent body. Detailed petrologic descriptions of the unique achondrites, recrystallized diogenite Yamato-74013, and the rapidly cooled eucrite Yamato-74450 with pyroxene phenocrysts are given. It is inferred from the bulk chemistry and the mineralogical reexamination of Yamato-75028 that it is composed of the H5-type clasts and chondrule-rich H(L)3-like matrix with the H5 fragments. A close relationship in the collisional evolution of some asteroids with these materials is inferred.
    Keywords: LUNAR AND PLANETARY EXPLORATION
    Type: National Institute of Polar Research, Memoirs (ISSN 0386-0744); 15, 1; 54-76
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  • 43
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    The maturation of lunar dust grains (1975)
    In:  CASI
    Details
    Publication Date: 2005-02-24
    Keywords: LUNAR AND PLANETARY EXPLORATION
    Type: Res. in the Space Sci., Vol. 2, No. 1; 3 p
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  • 44
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    Toward diffraction-limited seeing of dim astronomical objects from the Earth's surface using LIDAR (1977)
    In:  CASI
    Details
    Publication Date: 2005-02-28
    Keywords: ASTRONOMY
    Type: Res. in the Space Sci., Vol. 2, No. 1; 12 p
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  • 45
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    The High Resolution Spectrograph for the Space Telescope (1982)
    In:  CASI
    Details
    Publication Date: 2009-11-16
    Description: The High Resoltuion Spectrograph (HRS) in conjunction with the Space Telescope (ST), extends ultraviolet astronomical spectroscopy to higher spectra, spatial, and time resolutions than previously achieved, as well as to fainter and more distant celestial objects. Other significant advances inherent in the instrument are high photometric accuracy and efficient operation via exposure meter control and real time rejection of bad data. These capabilities are provided to accomplish the scientific programs of the HRS investigation definition team, which concern the interstellar medium, stellar winds, and evolutionary aspects of stellar atmosphere studies; the determination of chemical abundances relevant to stellar evolution; the investigation of quasars and Seyfert galaxy nuclei; and the analysis of the atmospheres of solar system objects, including comets.
    Keywords: ASTRONOMY
    Type: Space Telescope Science Inst. The Space Telescope Obs.; p 76-105
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  • 46
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    Ode to gravity: Depth/diameter for fresh craters on Mercury (1984)
    In:  CASI
    Details
    Publication Date: 2009-11-23
    Description: Opinions conflict over the role of surface gravity in shaping impact craters on Mercury. One view holds that the effects of g are evident in measurable aspects of crater form; other investigators find little or no evidence for g's geomorphic importance. Ambiguity in the role of g and other variables in cratering on Mercury stems largely from uncertainty in identifying major geomorphic contrasts and the crater sizes at which they occur. One of these, depth/diameter (d/D), undergoes a major change at the transition from simple (bowl shaped) to complex (peaks and terraces) crater interiors. Four least-squares d/D fits for fresh craters on Mercury were attemped. The results are inconsistent. The d/D data that should resolve previous shortcomings is presented. The revised d/D distributions for simple and complex craters, which intersect at a diameter of about 5 km, support the initial thesis that g substantially influences the form of Mercury's craters.
    Keywords: LUNAR AND PLANETARY EXPLORATION
    Type: NASA. Washington Rept. of Planetary Geol. Program, 1983; p 104-106
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  • 47
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    Infrared astronomy and high energy astrophysics (1977)
    In:  CASI
    Details
    Publication Date: 2006-08-09
    Description: Observations of the diffuse far-infrared flux from the galactic plane, as well as far-infrared measurements of the properties of dense molecular clouds, when combined with recent high-energy gamma-ray measurements and radio observations of carbon monoxide, yield information about the total mass of molecular clouds, the large-scale structure of the inner galaxy, and the density of cosmic rays.
    Keywords: ASTRONOMY
    Type: The Struct. and Content of the Galaxy and Galactic Gamma Rays; p 203-214
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  • 48
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    Meteoroid protection for the Comet Halley probe (1979)
    In:  CASI
    Details
    Publication Date: 2006-06-26
    Description: The high closing speed of 57km/s between the spacecraft and Halley poses special problems in the design of the required meteoroid protection. A double wall structure with a total thickness equal to 0.1 to 1 times the diameter of the largest meteoroid encountered is sufficient to stop that meteoroid. However, the unusually high number of meteoroid impacts on the Halley probe will cause significant erosion of the outer wall so that failure of the second wall is more likely to occur from a small meteoroid passing through a previously created hole in the outer wall and then penetrating the second wall. Calculations of the shielding required based on this failure mode, show that a double wall structure must actually have a total thickness 1.2 to 7.3 times the diameter of the largest meteoroid encountered, depending on the size distribution of the meteoroids.
    Keywords: LUNAR AND PLANETARY EXPLORATION
    Type: ESA Comet Halley Micrometeoroid Hazard Workshop; p 73-76
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  • 49
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    Relationships and tectonics of the Jg-7 quadrangle of Ganymede (1984)
    In:  CASI
    Details
    Publication Date: 2006-04-06
    Description: Craters within the Ganymede Jg-7 quadrangle were divided into seven mappable units. The units represent: (1) irregular or elongate craters, (2) craters with dark ejecta, (3) palimpsests, (4) secondary craters, (5) and craters of young, mature, and old age. Symbols used for crater floors include: (1) flat floors, (2) floors with pits, (3) floora with a central dome or peak, (4) and floors with a central dome and pit. Grooved terrains were divided into five mappable units. Three units of light grooved material represent small, medium, and large grooves, which are arbitrarily divided. The other two units of grooved terrain represent dark grooved materials, and reticulate grooves. Two units of ungrooved dark terrain and two units of ungrooved light terrain were defined. In Galileo Regio, two units were defined repesenting large furrowed grooves, and smaller grooves which are orthogonal to the furrowed grooves.
    Keywords: LUNAR AND PLANETARY EXPLORATION
    Type: NASA. Washington Rept. of Planetary Geology Program, 1983; p 314-316
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  • 50
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    Mars paleostratigraphy (1984)
    In:  CASI
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    Publication Date: 2006-04-06
    Description: The relative time of emplacement of some major rock units on Mars was recognized to some degree from geologic mapping using Mariner Images. Correlation charts showing the map units and their position in sequence, however, displayed little discrimination in their vertical range of occurrence. A more detailed time-stratigraphy is currently being developed as Viking geologic mapping of the planet progresses.
    Keywords: LUNAR AND PLANETARY EXPLORATION
    Type: NASA. Washington Rept. of Planetary Geology Program, 1983; p 296-297
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  • 51
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    Mapping and geological analysis of Mercury radar data (1984)
    In:  CASI
    Details
    Publication Date: 2006-04-06
    Description: Although many radar profiles and images of the area within 20 deg of Mercury's equator had been obtained from 1971 to 1981, at both Goldstone and Arecibo radar facilities, surprisingly little geological analysis had been done with these data until recently. Topographic profiles and radar roughness reflectivity images which can be derived from these data will be crucial in completing the geological mapping of Mercury now underway at the U.S. Geological Survey. Processing of available radar data must be completed to establish any systematic relationship between radar reflectivities and roughness, density, dielectric constant, and other related geological parameters. Specific tasks accomplished for these purposes include the following. Documentation was located and searched to establish the type and quantity of Goldstone 12.5 cm radar observations which were available for Mercury. Data has been collected during approximately 50 observation periods from 1971 to 1981. About half of the data, collected during 1972 and 1973, have been processed, but without adequate documentation. A standardized, well-documented procedure for processing and analysis for all Goldstone Earth-based observations of Mercury was established.
    Keywords: LUNAR AND PLANETARY EXPLORATION
    Type: NASA. Washington Rept. of Planetary Geology Program, 1983; p 284-286
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  • 52
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    The case for aeolian control of meter-scale surface texture on Mars (1984)
    In:  CASI
    Details
    Publication Date: 2006-04-06
    Description: The origin of Mars surface units and the extent of subsequent cratering play key roles in determining surface texture. At scale sizes of 0.1-10 meters, however, there is a growing body of evidence that wind is the dominant force. The direct and indirect evidence which implies that meter-scale surface texture on Mars is controlled by the wind is presented. Since radar is uniquely sensitive to structure on these scales, radio wave scattering data can provide insight on aeolian activity available from no other source.
    Keywords: LUNAR AND PLANETARY EXPLORATION
    Type: NASA. Washington Rept. of Planetary Geology Program, 1983; p 273-275
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  • 53
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    Ancient volcano-tectonic structures of the Olympus Mons Region, Mars (1984)
    In:  CASI
    Details
    Publication Date: 2006-04-06
    Description: Two old volcano-tectonic collapse structures are exposed north and northeast of the huge shield volcano, Olympus Mons. They are semicircular and were probably low shield volcanoes similar to Alba Patera, but whose central portions have subsided or collapsed. They form the basement upon which younger volcanic materials of Alba Patera Olympus Mons have been emplaced. The oldest structure, Acheron Fossae is over 700 km across and is north of Olympus Mons. It has a surface of considerable relief broken by graben and extensive en echelon and parallel fractures and faults with varied displacements. Acheron Fossae is the most densely cratered in the Olympus Mons region. The structure must have formed very early in martian time. The second is Halex Fossae, northeast of Olympus Mons. Where exposed, it is cut by a series of arcuate grabens that become closer spaced toward its center. The radii of the fractures indicate that the structure may be at least 250 km across and centered beneath the Olympus Plains. Lava flows appear to have issued from some of the arcuate fractures and to have flowed radially away from the center of Halex Fossae. North of Halex Fossae, material of the same age as Halex Fossae overlaps Acheron Fossae.
    Keywords: LUNAR AND PLANETARY EXPLORATION
    Type: NASA. Washington Rept. of Planetary Geology Program, 1983; p 293-295
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  • 54
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    Thermal infrared analysis of volcanic surfaces: Mars and Hawaii (1984)
    In:  CASI
    Details
    Publication Date: 2006-04-06
    Description: High spatial resolution data from the Viking infrared thermal mapper (IRTM) are used to examine the Tharsis volcanoes which are situated within a vast area of low thermal inertia material very fine particle size or very high porosity, with the volcanoes having the lowest thermal inertias. Thermal infrared images of the 1823 flow on Kilauea's southwest rift zone show lower thermal inertias near the vent area where shelly pahoehoe is common while individual channelized aa flows with abundant broken pahoehoe slabs are higher thermal inertia. The increase in aa flows to the southeast leads to a general trend of increasing thermal inertias from near vent to distal areas. Martian shield volcanoes have thermal inertias equal to or higher than their surrounding plans when atmospheric effects are removed from the data. The general increase in thermal inertias away from the summit calderas is consistent with the trend of the Hawaiian 1823 flow and may be related to changing lava properties away from the summit.
    Keywords: LUNAR AND PLANETARY EXPLORATION
    Type: NASA. Washington Rept. of Planetary Geology Program, 1983; p 266-267
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  • 55
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    Galilean satellite multispectral data base production (1984)
    In:  CASI
    Details
    Publication Date: 2006-04-06
    Description: A photometrically and geometrically reduced data base is being produced for the Galilean Satellites using Voyager Imaging data. The basic data set used is essentially all the useful satellite images returned by Voyager. Each frame was radiometrically calibrated and many are projected into cartographic formats. Mosaics of low, medium and high resolution frames being made for each satellite consist of registered digital images with intensity values scaled through a traceable calibration procedure to normal albedo values. Many of the mosaics are being made in two versions. One version is an albedo version and the second is a maximum discrimination version in which large variations in brightness across the picture are suppressed.
    Keywords: LUNAR AND PLANETARY EXPLORATION
    Type: NASA. Washington Rept. of Planetary Geology Program, 1983; p 259-260
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  • 56
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    Inversion of topography in Martian highlands terrains (1984)
    In:  CASI
    Details
    Publication Date: 2006-04-06
    Description: One unique feature on Mars is the presence of ring furrows which are apparently produced by inversion of topography at the rims of partially buried craters. Ring furrows are flat-floored trenches, circular in plan view, forming rings 7 to 50 km in diameter. The moat is on the order of 0.5 km deep and 2 to 10 km wide, and it surrounds a flat topped circular mesa or plateau that is 5 to 40 km across. The central plateau is at the same elevation or lower than the surrounding plain outside the ring. The circular nature and size range of ring furrows tend to suggest that these features are related to craters partially buried by younger lava flows. The rings have been formed by preferential removal of the exposed crater rims. Ground ice decay, sapping, or fluvial erosion removed the less resistant, porous material of crater rims while leaving the more resistant volcanic flow material. Differential erosion has thus led to a reversal of topography in which the original positive relief of the rim is reduced to a negative relief feature.
    Keywords: LUNAR AND PLANETARY EXPLORATION
    Type: NASA. Washington Rept. of Planetary Geology Program, 1983; p 228-229
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    Permafrost on Mars: distribution, formation, and geological role (1984)
    In:  CASI
    Details
    Publication Date: 2006-04-06
    Description: The morphology of channels, valleys, chaotic and fretted terrains and many smaller features on Mars is consistent with the hypothesis that localized deterioration of thick layers of ice-rich permafrost was a dominant geologic process on the Martian surface. Such ground ice deterioration gave rise to large-scale mass movement, including sliding, slumping and sediment gravity flowage, perhaps also catastropic floods. In contrast to Earth, such mass movement processes on Mars lack effective competition from erosion by surface runoff. Therefore, Martian features due to mass movement grew to reach immense size without being greatly modified by secondary erosional processes. The Viking Mission to Mars in 1976 provided adequate measurements of the relevant physical parameters to constrain models for Martian permafrost.
    Keywords: LUNAR AND PLANETARY EXPLORATION
    Type: NASA. Washington Rept. of Planetary Geol. Programs; p 209-211
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    Dark streaks on talus slopes, Mars (1984)
    In:  CASI
    Details
    Publication Date: 2006-04-06
    Description: High-resolution pictures of talus slopes on Mars show small, dark streaks that characteristically widen downward. These streaks are different from the thin and even streaks of various albedos that stream from cliffs on talus slopes, but gradations between the two streak types occur and not all streaks can be classified with confidence. In order to study the nature and origin of the small, widening, dark streaks, all Viking pictures with a resolution of less than 100 m/pixel were surveyed. To date several hundred streaks were located, but only few are of high enough resolution to be confidently identified as widening downwards. The approximate dimensions of the streaks were measured and their shapes, numbers, position, and spacing on slopes were noted. They were plotted on a topographic map, and their relation to topography, geologic units, and regions of distinct thermal inertia and albedo were studied. Also noted was the season at which images containing streaks were acquired and the direction of illumination. Albedo measurements are in progress. Several streaks can be seen stereoscopically, but none are observed on color images. The observation of small dark streaks on talus slopes on Mars is compatible with an interpretation of their origin as eruptions of small masses of wet debris in places where steep walls intersect aquifers or where seasonal equatorial warming permits the local melting of ground ice.
    Keywords: LUNAR AND PLANETARY EXPLORATION
    Type: NASA. Washington Rept. of Planetary Geol. Programs; p 188-190
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    Freezing of Martian streams under climatic conditions (1984)
    In:  CASI
    Details
    Publication Date: 2006-04-06
    Description: The valley networks of Mars are widely believed to have formed at a time when climatic conditions on the planet were significantly different from those that currently prevail. This view arises from the following observations: (1) the valleys form integrated branching networks which suggests fluid drainage, and water is the most plausible fluid, (2) the present atmosphere contains only minute amounts of water, (3) the networks appear to be more akin to terrestrial valleys that are eroded by streams of modest discharges than features that form by catastrophic floods, and (4) small streams of water will rapidly freeze under present climatic conditions. Climatic conditions at the time of formation of the valleys are studied based on the assumption that they were cut by running water.
    Keywords: LUNAR AND PLANETARY EXPLORATION
    Type: NASA. Washington Rept. of Planetary Geol. Programs; p 185-187
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    Venus: The nature of the surface from Venera panoramas (1984)
    In:  CASI
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    Publication Date: 2006-04-06
    Description: Images of the surface of Venus obtained by the Soviet Venera 9, 10, 13 and 14 landers are analyzed to provide a basis for understanding the nature of geologic processes operating there. Bedrock is exposed at the Venera 10, 13 and 14 sites and is characterized by semi-continuous, flat polygonal to subrounded patches up to several meters in width. The bedrock surface is often dominated by sub horizontal to horizontal layered plates with thicknesses of several cm and abundant linear and polygonal vertical fractures. Soils (particles 1 cm) are abundant at the Venera 9, 10 and 13 sites, but are uncommon at Venera 14. Features indicative of a strong aeolian influence (moats, dunes, wind tails) are not observed. Several hypotheses are considered for the origin of the bedrock surfaces, and it is concluded that bedrock originated from surface lava flows. The relative freshness of features observed by the Veneras suggests that erosion rates are very low or that some bedrock surfaces are geologically young.
    Keywords: LUNAR AND PLANETARY EXPLORATION
    Type: NASA. Washington Repts. of Planetary Geol. Program; p 76-78
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    Venus banded terrain: Evaluation of tectonic models for the origin of banding (1984)
    In:  CASI
    Details
    Publication Date: 2006-04-06
    Description: A tectonic orgin for Venus banded terrain is consistent with band spacing. Both compressional (folding) and extensional models for band formation can fit present observations. Band spacing cannot distinguish among scenarios for global heat loss and for the origin of highland terrain. Tectonic models for band formation indicate that the surface brittle layer in the venus highlands is no more than a few kilometers thick.
    Keywords: LUNAR AND PLANETARY EXPLORATION
    Type: NASA. Washington Repts. of Planetary Geol. Program; p 74-75
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    Wind abrasion on Venus: A means for experimental investigations (1984)
    In:  CASI
    Details
    Publication Date: 2006-04-06
    Description: A study to determine the feasibility of conducting experiments to simulate the aeolian environment on Venus as related to wind abrasion was completed. Ideally, such experiments should involve complete investigation of weathering, in which mechanical, thermal, and chemical parameters are taken into account. This is particularly important for Venus, where atmospheric temperatures and pressures at the surface produce an environment which is equivalent to low or medium grade metamorphic conditions on Earth. Details that describe the Venus Aeolian Abrasion Device (VAAD) are included. The VAAD device would enable experiments to be conducted with the same chemistry, temperature, pressure, and other physical properties of the Venus atmosphere near the surface. The proposed device enables the important aeolian parameters to be controlled and monitored, including particle size, velocity, impact-angle and flux, atmospheric pressure, temperature, and gas composition.
    Keywords: LUNAR AND PLANETARY EXPLORATION
    Type: NASA. Washington Repts. of Planetary Geol. Program; p 67-68
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    The Borealis Basin of Mars (1984)
    In:  CASI
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    Publication Date: 2006-04-06
    Description: Why the lowlands of Mars are concentrated in the Northern Hemisphere and the highlands in the Southern Hemisphere is probably the most fundamental unsolved problem in martian geology. No explanation that accounts both for this asymmetric distribution and for the isostatic equilibrium across the scarp or sloping transition zone dividing the two provinces has been generally accepted; thinning of the lithosphere in the northern hemisphere by internal processes has been suggested. Because other lowland-highland distributions on Mars, Moon, and Mercury are controlled by impact basins, it is proposed that a giant basin formed early in Mars' history has caused the martian hemispheric dichotomy as well.
    Keywords: LUNAR AND PLANETARY EXPLORATION
    Type: NASA. Washington Rept. of Planetary Geol. Program, 1983; p 110-112
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    Does saturation cratering exist in the solar system? (1984)
    In:  CASI
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    Publication Date: 2006-04-06
    Description: A number of researchers have concluded that saturation equilibrium cratering exists nowhere in the solar system, and therefore that diameter distributions in even the most heavily cratered provinces reveal initial production functions related to impacting bodies. Based on this premise, different populations of impactors are identified in different epochs and regions of the solar system. These hypotheses are clearly crucial to interpreting planetary history and need further independent examination. The production function in the outer solar system may differ from that in the inner solar system, but it is also possible that viscous relaxation of ice craters or immediate flooding of craters that penetrate through an ice lithosphere into watery substrate may explain the greater deficiency of large craters on icy moons. This problem is controversial and needs more study.
    Keywords: LUNAR AND PLANETARY EXPLORATION
    Type: NASA. Washington Rept. of the Planetary Geol. Program, 1983; p 97-99
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    Morphology of fresh craters on Ganymede and the origin of pedestal craters (1984)
    In:  CASI
    Details
    Publication Date: 2006-04-06
    Description: Properties of the planetary surface and subsurface can affect the morphology of impact craters. A mechanism was proposed to explain pedestal craters and domed floors within fresh craters on Ganymede. Voyager 1 and 2 images with resolutions = to or 3.2 km/lp were examined and 523 fresh craters were identified. For each crater, the rim and ejecta diameters were measured, and the crater was characterized by ejecta class(es), interior features, floor morphology and target terrain. Of the craters examined, 97 show moderate to prominent doming of the crater floor; 340 craters have continuous ejecta which terminates in a scarp pedestal craters, of which 86 (25%) have a high albedo diffuse deposit beyond the pedestal.
    Keywords: LUNAR AND PLANETARY EXPLORATION
    Type: NASA. Washington Rept. of Planetary Geol. Program, 1983; p 94-96
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    Mercury: New identification of ancient multi-ring basins and implications for geologic evolution (1984)
    In:  CASI
    Details
    Publication Date: 2006-04-06
    Description: A systematic survey of the entire Mariner 10 coverage of Mercury was performed to determine the number, distribution and dimensions of additional ancient basins on the planet. Ancient multi-ringed basins on Mercury can be recognized by the following criteria: (1) arcs of massif chains and isolated massifs that protrude through younger units, (2) arcuate segments of lobate ridges (rupes) that align with massifs in circular patterns, (3) arcuate scarps that are aligned with ridges and massif, and (4) isolated regions of anomalously high topography within the intercrater regions of heavily cratered terrain. All of the newly identified basins predate the mercurian intercrater plains, previously held to be the oldest geologic unit on the planet. Subsequent structural evolution of various regions was influenced by the presence of these basins. Smooth plains units appear to be more extensive than mapped by Mariner 10 and more than 90 percent of them appear to be basin contained or basin related. The concentration of extensive smooth plains material within and associated with basin structural and depositional environments suggests a volcanic origin for most of this unit, analogous to the lunar maria. Basins appear to provide the basic structural pattern of early terrestrial planetary crusts.
    Keywords: LUNAR AND PLANETARY EXPLORATION
    Type: NASA. Washington Rept. of Planetary Geol. Program, 1983; p 87-89
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    Venus: Global distribution of Pioneer-Venus radar roughness and reflectivity and global correlation of altimetry, roughness and reflectivity observations (1984)
    In:  CASI
    Details
    Publication Date: 2006-04-06
    Description: An improved version of the Pionner-Venus orbital data was used for a statistical analysis of global radar roughness and (alpha(0)) (rho) reflectivity. Classification maps of the venusian surface are produced in a supervised manner on the basis of statistical and empirical studies of the individual data sets. The primary objective is to assess the degree of homogeneity of surface radar properties within topographic provinces in order to map possible geologic boundaries. Maps were produced by correlating two data sets at a time. Classification of specific regions, such as Ishtar, has demonstrated that distinct geological units can be identified.
    Keywords: LUNAR AND PLANETARY EXPLORATION
    Type: NASA. Washington Repts. of Planetary Geol. Program; p 81-82
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    New maps of Lakshmi Planum and eastern Aphrodite, Venus (1984)
    In:  CASI
    Details
    Publication Date: 2006-04-06
    Description: Interest on Venus has centered on three regions; (1) Aphrodite Terra, especially east of the main uplant portion, (2) Ishtar Terra, especially Lakshmi Planum and its bounding scarp and massifs, and (3) Beta Regio-Phoebe Regio. The last region is topographically similar to the East African rift system, and has been inferred to have a similar tectonic origin. The Aphrodite region is part of a 21,000 km long tectonic zone that seems best explained as due to extension, and that may represent hot spots clustered along an incipient divergent plate boundary. The most interesting and complex portion of this tectonic zone is that part of eastern Aphrodite between Thetis Regio and Atla Regio. In contrast, the Lakshmi Planum region has many topographic characteristics suggesting that it is a true continent, and thus indicative of convergence and a thick crust. Detailed topographic contour maps of eastern Aphrodite Terra and of Lakshmi Planum are included.
    Keywords: LUNAR AND PLANETARY EXPLORATION
    Type: NASA. Washington Repts. of Planetary Geol. Program; p 71-73
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    Recent comet impacts on the moon: The evidence from spectral reflectance studies (1984)
    In:  CASI
    Details
    Publication Date: 2006-04-06
    Description: The results of analyses of near infrared reflectance spectra are inconsistent with numerous previous interpretations of the Reiner Gamma Formation. These include: (1) nue ardente or volcanic ash deposits, (2) volcanically derived sublimates, (3) high albedo volcanic deposits, and (4) highlands debris emplaced as impact ejecta. These results, strongly suggest that the selective preservation of high albedo features (formed by secondaries) by a local magnetic field enhancement is not a viable hypothesis. The results are generally consistent with, but place constraints on, the cometary impact hypothesis of Schultz and co-workers. While the presence of a magnetized component was not detected in either the bright or dark portions of the Reiner Gamma Formation, this material may be present in amounts under the current detection limits.
    Keywords: LUNAR AND PLANETARY EXPLORATION
    Type: NASA. Washington Repts. of Planetary Geol. Program; p 59-61
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    Cometary nucleus and active regions (1984)
    In:  CASI
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    Publication Date: 2006-04-06
    Description: On the basis of the icy conglomerate model of cometary nuclei, various observations demonstrate the spotted nature of many or most nuclei, i.e., regions of unusual activity, either high or low. Rotation periods, spin axes and even precession of the axes are determined. The observational evidence for variations in activity over the surfaces of cometary nuclei are listed and discussed. On June 11 the comet IRAS-ARAKI-ALCOCK approached the Earth to a distance of 0.031 AU, the nearest since C/Lexell, 1770 I, providing a unique opportunity for near-nucleus observations. Preliminary analysis of these images establishes the spin axis of the nucleus, with an oblioquity to the orbit plane of approximately 50 deg, and a lag angle of sublimation approximately 35 deg from the solar meridian on the nucleus. Asymmetries of the inner coma suggests a crazy-quilt distribution of ices with differing volatility over the surface of the nucleus. The observations of Comet P/Homes 1892 III, exhibiting two 8-10 magnitude bursts, are carefully analyzed. The grazing encounter produced, besides the first great burst, an active area on the nucleus, which was rotating retrograde with a period of 16.3hr and inclination nearly 180 deg. After the first burst the total magnitude fell less than two magnitudes from November 7 to November 30 (barely naked eye) while the nuclear region remained diffuse or complex, rarely if ever showing a stellar appearance. The fading was much more rapid after the second burst. The grazing encounter distributed a volume of large chunks in the neighborhood of the nucleus, maintaining activity for weeks.
    Keywords: LUNAR AND PLANETARY EXPLORATION
    Type: NASA. Washington Repts. of Planetary Geol. Program; p 51-53
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    Geology of Dione (1984)
    In:  CASI
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    Publication Date: 2006-04-06
    Description: Dione is one of the most geologically complex of the Saturnian satellites. Crater counts and surface morphology indicates the geologic units observed are of variable age and origin. In an attempt to understand the processes which have affected Dione, a geologic map was prepared. Several geologic units were identified; ancient heavily cratered terrain, two plains units: cratered plains and lightly cratered plains, lobate deposits, crater rim deposits and bright wispy materials.
    Keywords: LUNAR AND PLANETARY EXPLORATION
    Type: NASA. Washington Repts. of Planetary Geol. Program; p 34-36
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    Theoretical aspects of photoclinometric terrain profiling on the Galilean satellites (1984)
    In:  CASI
    Details
    Publication Date: 2006-04-06
    Description: For large parts of the surfaces of the Galilean satellites there is no stereoscopic high resolution imagery, and so for shadow-free regions far from the terminator, the only method of obtaining topograpic information is photoclinometry, the technique of converting brightness variations into local surface tilts and hence into topographic profiles and contour maps. The conversion from brightness changes to slopes require knowledge of the angular photometric function for the type of planetary surface terrain being analyzed, i.e., the relationship describing the brightness of the surface as a function of the angles of incidence (I) and emergence (E) of light at a surface element. In order to investigate the effects of these changes on the shapes of topographic profiles deduced from the functions, an area of grooved terrain (lines 500-505, samples 550-650 on frame 20640.27 0060J2) using wide ranges of values of all the adjustable parameters in Hapke's new photometric function were analyzed.
    Keywords: LUNAR AND PLANETARY EXPLORATION
    Type: NASA. Washington Repts. of Planetary Geol. Program; p 27-28
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    The structure of the Ionian lithosphere (1984)
    In:  CASI
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    Publication Date: 2006-04-06
    Description: Exploratory work on the structure of the Ionian lithosphere is reported. The approach is to examine temperature profiles within the lithosphere that result from different distributions of sulfur and silicates and different conductive heat fluxes, then compare such profiles with observations in the expectation that only a limited set of the profiles are possible. In this preliminary work some rather simplistic assumptions were taken and the report should be viewed more as a demonstration of a method rather than a presentation of results.
    Keywords: LUNAR AND PLANETARY EXPLORATION
    Type: NASA. Washington Repts. of Planetary Geol. Program; p 11-13
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    Viking orbiter and its Mariner inheritance (1984)
    In:  CASI
    Details
    Publication Date: 2006-02-14
    Description: Improvements to the design of the Mariner spacecraft resulted in the Viking spacecraft. The Viking spacecraft would consist of two major systems - an orbiter and a lander, while the lander would provide the means for safely delivering the scientific instruments to the surface, house, and provide the necessary power source and communication links for those experiments, the orbiter would transport the lander to Mars, rovide a platform for the Viking imaging system so that proposed landing sites could be surveyed and certified, relay lander science information back to Earth, and conduct scientific observations in its own right.
    Keywords: LUNAR AND PLANETARY EXPLORATION
    Type: On Mars: Exploration of the Red Planet, 1958 - 1978; p 155-202
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    The PDS-VAX intelligent plate scanning system of Trieste Astronomical Observatory (1984)
    In:  CASI
    Details
    Publication Date: 2006-02-14
    Description: An intelligent subsystem for interfacing a PDS1010A digital microdensitometer to a DEC DR11W DMA 16 bit UNIBUS port in DEC VAX VMS environment was tested. The subsystem employs two MOTOROLA M68000 microprocessors with 128 KB data memory. The PDS primitives and the user defined high level scanning functions and preprocessing modules are loaded from the host computer into two 8 KB RAM memories in the microprocessors using a dedicated PDS control language. The subsystem is planned to employ a nonstandard photomultiplier electronics. Two design schemes were tested: (1) based on three amplifiers of gain 10 cascaded and multiplexed to a 12 bit AD converter, and (2) based on a single amplifier of gain 100 and two 14 bit AD converters.
    Keywords: ASTRONOMY
    Type: NASA. Goddard Space Flight Center Astron. Microdensitometry Conf.; p 175-187
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    Reflections on the Space Telescope (1982)
    In:  CASI
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    Publication Date: 2006-02-14
    Description: The significance of the Space Telescope for the advancement of astronomy and astrophysics is described. The current state of knowledge in astronomy and cosmology is summarized and unanswered questions in those fields discussed. The rapid evolution of modern astronomy and the need for systematic observations are stressed.
    Keywords: ASTRONOMY
    Type: Space Telescope Science Inst. The Space Telescope Obs.; p 121-134
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    Astrometric observations with the Space Telescope (1982)
    In:  CASI
    Details
    Publication Date: 2006-02-14
    Description: Astrometry with the Space Telescope (ST) is performed using one of the fine guidance sensors (FGS). The FGS, which is based on a pair of Koester's prism interferometers, one for each axis, is capable of measuring the position of one object relative to another with an accuracy of 0.002 arcseconds. Astrometric Data Reduction Software (ADRS) available to the astrometric user of ST is described. The kinds of problems the space telescope astrometry team plans to investigate using ST are discussed.
    Keywords: ASTRONOMY
    Type: Space Telescope Science Inst. The Space Telescope Obs.; p 114-120
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    The wide field/planetary camera (1982)
    In:  CASI
    Details
    Publication Date: 2006-02-14
    Description: A wide site of potential astronomical and solar system scientific studies using the wide field planetary camera on space telescope are described. The expected performance of the camera as it approaches final assembly and testing is also detailed.
    Keywords: ASTRONOMY
    Type: Space Telescope Science Inst. The Space Telescope Obs.; p 28-39
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    European astronomy and the Space Telescope: The Space Telescope European Coordinating Facility (1982)
    In:  CASI
    Details
    Publication Date: 2006-02-14
    Description: The role of the European Coordinating Facility is described. European participation in the Space Telescope Science Institute and the relation of Space Telescope to ground-based astronomy in Europe are discussed.
    Keywords: ASTRONOMY
    Type: Space Telescope Science Inst. The Space Telescope Obs.; p 16-19
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    A study of the cosmic sources of hard X-rays (1976)
    In:  CASI
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    Publication Date: 2006-04-18
    Description: An actively-shielded, high-energy X-ray telescope was launched onboard OSO-8 on 21 June 1975. The primary objectives of this experiment are the measurements of the energy spectrum of discrete cosmic X-ray sources in the range 20 keV to 3 MeV and of the temporal variations in the intensity of each source detected with a time resolution of 0.3 msec. This detector provides the highest duty factor and the finest time resolution of any of its kind for observations over a period of up to 10 days. The background spectrum of this detector in orbit was monitored continuously since shortly after launch. The minimum detectable source strength is estimated to be between 10,000 and 100,000 photons/sq-cm-sec keV, limited primary by the effects of induced radioactivity. From 16 July through 18 July 1975, the X-ray binary, Cen X-3, was observed with the hard X-ray telescope.
    Keywords: ASTRONOMY
    Type: X-ray Binaries; p 739-746
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    Simultaneous X-ray and optical observations of X Persei (1976)
    In:  CASI
    Details
    Publication Date: 2006-04-18
    Description: Photoelectric photometry of X Persei was obtained on five out of seven consective nights in January 1975, from the Lick and Leuschner Observatories. The observations yield B = 6.848 + or - 0.002, B-V = 0.139 + or - 0.001, with no strong evidence for variability during the observing run. These are the faintest and bluest photoelectric magnitudes and colors ever reported for X Per; this change apparently occured relatively uniformly during 1973-74 and is reminiscent of behavior last observed in approximately 1900. The suggested association of X Persei with the weak X-ray source 3U 0352+30 raises the possibility of detection of X-ray/optical covariability. On January 21, 1975, 7 hours of data were obtained from both observatories simulataneous with OAO Copernicus X-ray observations of 3U 0352+30. The X-ray data varied during this period by a factor of two, but there is no obviously correspondent optical activity, to a level of 0.02 mag. The optical data are also used to limit to 0.01 mag variations coincident with the X-ray periodicity.
    Keywords: ASTRONOMY
    Type: NASA. Goddard Space Flight Center X-ray Binaries; p 719-726
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    OSO-8 GSFC results on Cen X-3 (1976)
    In:  CASI
    Details
    Publication Date: 2006-04-18
    Description: Spectra of Cen X-3 during eclipse, in transition out of eclipse, and during several later phases of the binary orbit were obtained from quick look data of the July 16-25, 1975 observation by the Goddard X-ray spectroscopy experiment on OSO-8. In the high state there was no absorption turn over. Pulsations were present at least to 23 keV. The spectrum at the pulse minimum was flatter above 7 keV than that of the pulse peak. In transition out of eclipse Cen X-3 emerged above a small low energy flux seen during eclipse. The observations appear to indicate absorption by cold and ionized matter and the presence of iron in the companion's atmosphere. Decreased intensities were observed at late phases of some binary orbits in some cases corresponding to dips. Absorption appears although the low energy component remains. Variable features may be interpretable as absorption and emission by iron and possibly other trace elements.
    Keywords: ASTRONOMY
    Type: X-ray Binaries; p 207-218
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    X-ray spectroscopy with the ANS satellite (1976)
    In:  CASI
    Details
    Publication Date: 2006-04-18
    Description: Preliminary results from the Bragg crystal spectrometer on the ANS satellite are given. No significant Si XIII and Si XIV narrow line emission has been detected from Cygnus X-1, -2, or -3.
    Keywords: ASTRONOMY
    Type: NASA. Goddard Space Flight Center X-ray Binaries; p 49-52
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  • 84
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    OSO-8 observations of Hercules X-1 (1976)
    In:  CASI
    Details
    Publication Date: 2006-04-18
    Description: The X-ray binary Her X-1 was observed by the GSFC cosmic X-ray detectors aboard OSO-8 between August 26 and September 3, 1975. The results reported are based on quick look tapes which contain less than 10% of the total time spent on source. Spectra were observed during different phases of the binary period including the anomalous low state (dip) in X-ray intensity. The normal high spectra is well represented by a power law with a short cutoff above approximately 25 keV. A significant and varying enhancement in the intensity around 6.7 keV was observed, suggesting the presence of an iron line. Absorption was seen in the spectrum immediately following eclipse. The dip spectrum is found to be considerably flattened. Also spectra are presented for different phases of the pulse period.
    Keywords: ASTRONOMY
    Type: X-ray Binaries; p 161-168
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  • 85
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    Some features of the X-ray source Cyg X-3 (1976)
    In:  CASI
    Details
    Publication Date: 2006-04-18
    Description: Data from the Copernicus satellite are presented which show that the 4.8 hour light curve of Cyg X-3 has been relatively stable in period, shape, and amplitude since the observation of the first giant radio outburst in September 1972. A pulse height spectrum of the source obtained by the Ariel 5 satellite in the 1.5 to 26 kev energy band shows convincing evidence for line emission at about 6.5 keV. The strength of this feature varies in phase with the 4.8 hour continuum modulation, but there is no simple long term relation with the mean continuum intensity per 4.8 hour cycle. Evidence is presented which indicates that the average 2-6 kev intensity of Cyg X-3 has been higher by a factor of 3 since the onset of the radio flares.
    Keywords: ASTRONOMY
    Type: NASA. Goddard Space Flight Center X-ray Binaries; p 255-265
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  • 86
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    OSO-8 observing schedule for X-ray binaries (1976)
    In:  CASI
    Details
    Publication Date: 2006-04-18
    Description: Six different instruments on OSO-8 have observed several binary X-ray sources between energies of 0.13 keV and 1 MeV at various times since 21 June 1975. The schedule for these observations is given, as well as the present plan for such future observations through July 1976. Included is the OSO-8 observing schedule for the transient X-ray source A0620-00.
    Keywords: ASTRONOMY
    Type: X-ray Binaries; p 729-738
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  • 87
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    X-ray observation of 3U 1700-37 (1976)
    In:  CASI
    Details
    Publication Date: 2006-04-18
    Description: X-ray observations with Copernicus reveal three categories of flux variability in 3U 1700-37. High amplitude hourly variations are energy independent in the 3-11 keV range while a change in the low energy absorbing column causes variations in flux level on an orbital time scale. This absorption is most severe prior to eclipse ingress, suggesting that the distribution of absorbing material around the X-ray source is asymmetrical with respect to the line of centers of the binary system. The absorbing material may be identical with a high density region inferred from optical observations of HD 153919. In the third category, the maximum source intensity per binary cycle is variable by at least a factor of two between observations. Measurement of the eclipse duration on three occasions indicate that it is significantly less than when observed by Uhuru.
    Keywords: ASTRONOMY
    Type: NASA. Goddard Space Flight Center X-ray Binaries; p 559-567
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  • 88
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    A review of 3U 1700-37 = HD 153919 (1976)
    In:  CASI
    Details
    Publication Date: 2006-04-18
    Description: X-ray, spectroscopic, and photometric data for the source are reviewed briefly. Some points of controversy and difficulty are discussed. The X-ray source 3U 1700-37 is moderately strong (approximately 100 Uhuru counts) and shows a long eclipse, with a period of 3.412 days. The X-rays are attenuated near 0.5 phase, and show a very wide gradual decrease on either side of the total eclipse. The low-energy cutoff is the strongest of all the X-ray binaries. These characteristics are all qualitatively compatible with the optical star's, which represent an extreme in several ways: (1) the primary is an extreme star with large mass outflow through a spherically symmetric stellar wind; (2) it is the hottest of all X-ray binary primaries (with possible exception of Cen X-3); and (3) the mass ratio is very high and the relative separation of the stars is low.
    Keywords: ASTRONOMY
    Type: NASA. Goddard Space Flight Center X-ray Binaries; p 531-535
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  • 89
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    The nature of the X-ray nova A0620-00 (1976)
    In:  CASI
    Details
    Publication Date: 2006-04-18
    Description: A model is presented for the X-ray nova A0620-00. Identification with a nova can be ruled out on two counts. A binary consisting of a late-type subgiant near the Roche lobe, irradiated by an accreting compact companion is shown, however, to be in agreement with all known observations. Photometry of the optical object should be pursued since variability on an approximately eight hour period is expected.
    Keywords: ASTRONOMY
    Type: X-ray Binaries; p 361-367
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  • 90
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    New results from long-term observations of Cyg X-1 (1976)
    In:  CASI
    Details
    Publication Date: 2006-04-18
    Description: Observations of Cyg X-1 between October 1974 and July 1975 reveal a persistent 5.6 day modulation of the 3-6 keV X-ray intensity, having a minimum in phase with superior conjunction of the HDE 226868 binary system. The modulation is found to be most pronounced just prior to the April-May 1975 increase of Cyg X-1, after which both the modulation and intensity are at their lowest values for the entire duration of the observations. These data imply that the X-ray emission from Cyg X-1 arises from the compact member of HDE 226868, and that the increase of April-May 1975 may have represented the depletion of accreting material which had not yet been mixed into a cylindrically symmetric accretion disk about the compact member.
    Keywords: ASTRONOMY
    Type: X-ray Binaries; p 391-405
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  • 91
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    The interpretation of optical light variations of Centaurus X-3 (1976)
    In:  CASI
    Details
    Publication Date: 2006-04-18
    Description: The interpretation of optical light variations of X-ray binaries is discussed for the case of negligible reflection effect. The limiting cases of synchronous rotation of the visible star (Roche configuration) and of no rotation (pure tidal deformation) are considered. The theoretical results are compared with the available light curves of Cen X-3. X-ray data of the Copernicus satellite are used to get an impression of the atmospheric structure of the outer layers of the visible component. It is shown, that the X-ray eclipse duration is in good agreement with the mass ration derived from the optical variations. The X-ray eclipse duration is discussed with respect to the extended low states, and a possible correlation of the extended lows with the appearance of the optical light curves is considered.
    Keywords: ASTRONOMY
    Type: NASA. Goddard Space Flight Center X-ray Binaries; p 179-185
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  • 92
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    The observation program for the GSFC cosmic X-ray spectroscopy experiment (1976)
    In:  CASI
    Details
    Publication Date: 2006-04-18
    Description: The cosmic X-ray spectroscopy experiment on OSO-8 will observe seven X-ray binary sources in its first six months of operation. If possible, each of these sources will be observed for one or more binary orbits so that the X-ray spectrum of each object can be observed through all phases of its orbit. For the two pulsing binaries, Her X-1 and Cen X-3, spectral variations over the pulse period will be studied. Simultaneous radio observations of Cyg X-1 and Cyg X-3 will search for any correlation between radio and X-ray emission. During the first year of operation, the detectors will observe over 50% of the known X-ray sources.
    Keywords: ASTRONOMY
    Type: X-ray Binaries; p 737-738
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  • 93
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    Spectrophotometry of the unusual optical candidate for 3U 1728-24 (=GX 2+5 = GX 1+4) a recurrent nova? (1976)
    In:  CASI
    Details
    Publication Date: 2006-04-18
    Description: The spectrum of the object suggested as a possible optical counterpart of GX 2+5, was studied, using the image tube scanner attached to the 3-m telescope of Lick Observatory. An improved X-ray error box obtained with Copernicus strongly supports this proposed identification. The candidate displays all the characteristics of the symbiotic stars and the related recurrent novae. The spectrum reveals the presence of an M star together with a blue component and a large number of emission lines displaying a wide range of ionization. There is evidence of variability of both the continuum and the line intensities. This object provides strong support for the often proposed association of some X-ray sources with nova-like systems.
    Keywords: ASTRONOMY
    Type: NASA. Goddard Space Flight Center X-ray Binaries; p 691-701
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  • 94
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    Long term X-ray studies of Sco X-1 (1976)
    In:  CASI
    Details
    Publication Date: 2006-04-18
    Description: No modulation of the 3-6 keV X-ray intensity of Sco X-1 at a level of excess of 1% is observed at the optical period of .787313d. Evidence is found for shot-noise character in a large fraction or the X-ray emission. Almost all of the Sco X-1 emission can be synthesized in terms of approximately 200 shots per day, each with a duration of approximately 1/3 day.
    Keywords: ASTRONOMY
    Type: X-ray Binaries; p 703-716
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  • 95
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    The X-ray binary HD 77581 + 3U 0900-40 (1976)
    In:  CASI
    Details
    Publication Date: 2006-04-18
    Description: The properties of the binary system in the different regions of the electromagnetic spectrum are presented from X-rays to the radio. Physical parameters and a model for the system are derived.
    Keywords: ASTRONOMY
    Type: NASA. Goddard Space Flight Center X-ray Binaries; p 575-614
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  • 96
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    The Skylab S019 ultraviolet spectra of HD 153919 (=3U 1700-37) and HDE 226868 (=Cyg X-1) (1976)
    In:  CASI
    Details
    Publication Date: 2006-04-18
    Description: Ultraviolet spectra of HD153919 (=3U1700-37) and HDE226868 (=Cyg X-1) were obtained with the ultraviolet objective-prism spectrograph of Skylab Experiment S019. The data consist of unwidened spectra which extend to 1,600A for HD153919 and to 2,400A for HDE226868. The wavelength resolution is about 2A to 1,400A and 12A at 2,000A. For HD153919, an unwidened spectrum of fair quality and extending to a wavelength of 1,600A was obtained at 22 sup h 08 sup m on 1 September 1973. The energy distribution in this spectrum generally resembles that of other reddened O stars. A break in continuum intensity seems to occur at a wavelength of about 1,720A. There is a suggestion of an emission line on the longward edge of the break but this could be either a chance clumping of grains or else a photographic edge-effect caused by the break.
    Keywords: ASTRONOMY
    Type: X-ray Binaries; p 551-553
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  • 97
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    High resolution measurements of Cyg X-1 from rockets (1976)
    In:  CASI
    Details
    Publication Date: 2006-04-18
    Description: Cyg X-1 was observed on two occasions (Oct. 4, 1973 and Oct. 3, 1974) by the Goddard X-ray rocket payload. This payload consisted of two gas proportional counters (xenon-methane with 710 sq cm and argon-methane with 610 sq cm using the same 128 channel pulse height analyzer and having 320 micro sec temporal resolution on the 1973 flight and 160 micro sec resolution on the 1974 flight. During both flights, bursts of 1 ms duration were observed with very high statistical certainty. To date all 13 of these bursts were analyzed for spectral and temporal character, and the results of this analysis are presented. The spectra of overall X-ray emission from both flights is also presented. In a source known for its variability, it is remarkable that the spectra taken one year apart are virtually identical.
    Keywords: ASTRONOMY
    Type: X-ray Binaries; p 443-451
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  • 98
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    The early light curve of A0620-00 (1976)
    In:  CASI
    Details
    Publication Date: 2006-04-18
    Description: The Ariel-5 All-Sky Monitor measured the 3-6 keV X-ray intensity of 0620-00 for two days shortly after peak emission in August 1975, and continuously throughout September 1975. The effective exposure each day for this source (and every other source in the 80% of the celestial sphere covered by the monitor) is approximately 250 sq cm sec. The light curve obtained through October 1 (when the spin axis was again pointed to A0620-00) is shown. The intensity difference at maximum is obviously a manifestation of the very soft spectrum of the source. Clearly, A0620-00 was approximately four times as bright as Sco X-1 at maximum in the band 3-6 keV. The decay is quite smooth, but cannot be fit with a single e-folding time. The interval between the early All-Sky Monitor points and the onset of continuous coverage has an inferred e-folding time of 22 days, but it is continually increasing throughout September. A0620-00 is apparently similar in its X-ray character to the very strong, long-lasting transient X-ray sources which presently number six. In contrast, only three can be sensibly reconciled with the lower-intensity, shorter-duration hard-spectrum transients which have been found to pulse on a time scale of minutes.
    Keywords: ASTRONOMY
    Type: X-ray Binaries; p 311-316
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  • 99
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    Absence of iron line emission in Cyg X-3 (1976)
    In:  CASI
    Details
    Publication Date: 2006-04-18
    Description: An observation of Cygnus X-3 was made with soft X-ray detectors launched on an Aerobee rocket. The iron line emission observed one month later and in May 1975 was not found. A 3 sigma upper limit for this feature is 0.006 ph/2 cm/s.
    Keywords: ASTRONOMY
    Type: NASA. Goddard Space Flight Center X-ray Binaries; p 285-292
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  • 100
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    The radio sources associated with Cyg X-3 (1976)
    In:  CASI
    Details
    Publication Date: 2006-04-18
    Description: Some of the conclusions derived from the data on the radio flaring of Cyg X-3 are summarized. In addition, recent data showing that Cyg X-3 has both active and quiet radio behavior are presented.
    Keywords: ASTRONOMY
    Type: NASA. Goddard Space Flight Center X-ray Binaries; p 233-244
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