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  • Chemistry  (82,579)
  • General Chemistry  (16,150)
  • Analytical Chemistry and Spectroscopy  (6,520)
  • Chemical Engineering  (4,231)
  • ASTRONOMY
  • 1995-1999  (38,789)
  • 1980-1984  (35,448)
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  • 1
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    Rational approaches to chemotherapy: antisickling agents (1981)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1981-08-14
    Description: 〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Klotz, I M -- Haney, D N -- King, L C -- New York, N.Y. -- Science. 1981 Aug 14;213(4509):724-31.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/7256275" target="_blank"〉PubMed〈/a〉
    Keywords: Anemia, Sickle Cell/*drug therapy ; Aspirin/analogs & derivatives/therapeutic use ; Chemical Phenomena ; Chemistry ; *Hemoglobin, Sickle ; Humans ; Protein Binding/drug effects ; Protein Conformation ; Salicylates/*therapeutic use ; Solubility ; Structure-Activity Relationship
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
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  • 2
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    Alpha-substituted gamma-butyrolactones: new class of anticonvulsant drugs (1982)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1982-09-10
    Description: Alkyl-Substituted gamma-butyrolactones were synthesized and tested for their convulsant and anticonvulsant actions in mice and guinea pigs. The alpha-substituted compounds, alpha, alpha-dimethyl-, and alpha-ethyl-alpha-methyl-gamma-butyrolactone were anticonvulsant compounds with a spectrum of activity similar to that of ethosuximide. In contrast, beta-substituted compounds were convulsant agents similar to picrotoxinin. The alpha-substituted-gama-butyrolactones represent a new class of anticonvulsant drug with experimental and clinical potential.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Klunk, W E -- McKeon, A -- Covey, D F -- Ferrendelli, J A -- GM-07200/GM/NIGMS NIH HHS/ -- GM-24483/GM/NIGMS NIH HHS/ -- NS-14834/NS/NINDS NIH HHS/ -- etc. -- New York, N.Y. -- Science. 1982 Sep 10;217(4564):1040-2.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/6810462" target="_blank"〉PubMed〈/a〉
    Keywords: *4-Butyrolactone/analogs & derivatives/*therapeutic use/toxicity ; Animals ; *Anticonvulsants ; Chemical Phenomena ; Chemistry ; Convulsants ; Drug Evaluation, Preclinical ; Electroencephalography ; Epilepsy, Absence/drug therapy ; Ethosuximide/pharmacology ; *Furans/*therapeutic use ; Guinea Pigs ; Mice ; Structure-Activity Relationship ; Trimethadione/pharmacology
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  • 3
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    Phase transition and crystal structure of the 37 degrees C form of cholesterol (1983)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1983-05-06
    Description: Crystalline cholesterol undergoes a phase transition a few degrees below human body temperature. The high-temperature form has an unusually complex structure with 16 independent molecules. In the transition two molecules change side chain conformation, four reorient about their long axes, and ten remain unchanged. The transition mechanism implies relatively nonspecific intermolecular interactions, qualitatively consistent with the behavior of cholesterol in biomembranes. The transition preserves a remarkably closely obeyed pseudosymmetry present in the structure.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Hsu, L Y -- Nordman, C E -- GM15259/GM/NIGMS NIH HHS/ -- New York, N.Y. -- Science. 1983 May 6;220(4597):604-6.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/6836303" target="_blank"〉PubMed〈/a〉
    Keywords: Body Temperature ; Chemical Phenomena ; Chemistry ; *Cholesterol ; Crystallization ; Humans ; Magnetic Resonance Spectroscopy ; Molecular Conformation
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  • 4
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    Cytochrome a3 structure in carbon monoxide-bound cytochrome oxidase (1984)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1984-07-20
    Description: The iron-carbon monoxide stretching mode and the iron-carbon-oxygen bending mode in carbon monoxide-bound cytochrome oxidase have been assigned at 520 and 578 cm-1, respectively. The frequencies, widths, and intensities of these modes show that the Fe-C-O grouping in carbon monoxide-cytochrome a3 is linear but tilted from the normal to the heme plane; that the iron-histidine bond in both five- and six-coordinate cytochrome a3 is strained; and that the carbon monoxide and the proximal histidine each have characteristic, well-defined orientations in all molecules. These data can account for the binding affinities of carbon monoxide and dioxygen under physiological conditions.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Argade, P V -- Ching, Y C -- Rousseau, D L -- New York, N.Y. -- Science. 1984 Jul 20;225(4659):329-31.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/6330890" target="_blank"〉PubMed〈/a〉
    Keywords: Animals ; Carbon Monoxide/metabolism ; Cattle ; Chemical Phenomena ; Chemistry ; Electron Transport Complex IV/*metabolism ; Myoglobin/metabolism ; Oxidation-Reduction ; Oxygen/metabolism ; Spectrum Analysis, Raman
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  • 5
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    Leukotrienes: mediators of immediate hypersensitivity reactions and inflammation (1983)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1983-05-06
    Description: Arachidonic acid plays a central role in a biological control system where such oxygenated derivatives as prostaglandins, thromboxanes, and leukotrienes are mediators. The leukotrienes are formed by transformation of arachidonic acid into an unstable epoxide intermediate, leukotriene A4, which can be converted enzymatically by hydration to leukotriene B4, and by addition of glutathione to leukotriene C4. This last compound is metabolized to leukotrienes D4 and E4 by successive elimination of a gamma-glutamyl residue and glycine. Slow-reacting substance of anaphylaxis consists of leukotrienes C4, D4, and E4. The cysteinyl-containing leukotrienes are potent bronchoconstrictors, increase vascular permeability in postcapillary venules, and stimulate mucus secretion. Leukotriene B4 causes adhesion and chemotactic movement of leukocytes and stimulates aggregation, enzyme release, and generation of superoxide in neutrophils. Leukotrienes C4, D4, and E4, which are released from the lung tissue of asthmatic subjects exposed to specific allergens, seem to play a pathophysiological role in immediate hypersensitivity reactions. These leukotrienes, as well as leukotriene B4, have pro-inflammatory effects.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Samuelsson, B -- New York, N.Y. -- Science. 1983 May 6;220(4597):568-75.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/6301011" target="_blank"〉PubMed〈/a〉
    Keywords: Animals ; Arachidonic Acids/metabolism/pharmacology/physiology ; Bronchi/drug effects ; Cats ; Chemical Phenomena ; Chemistry ; Cricetinae ; Guinea Pigs ; Haplorhini ; Humans ; Hypersensitivity, Immediate/*physiopathology ; Inflammation/*physiopathology ; Leukocytes/drug effects/metabolism ; Leukotriene B4/pharmacology/*physiology ; Mice ; Microcirculation/drug effects ; Rabbits ; Rats ; SRS-A/*physiology
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  • 6
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    Amphiphilic secondary structure: design of peptide hormones (1984)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1984-01-20
    Description: Peptide synthesis can be used for elucidating the roles of secondary structures in the specificity of hormones, antigens, and toxins. Intermediate sized peptides with these activities assume amphiphilic secondary structures in the presence of membranes. When models are designed to optimize the amphiphilicity of the secondary structure, stronger interactions can be observed with the synthetic peptides than with the naturally occurring analogs.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Kaiser, E T -- Kezdy, F J -- HL-18577/HL/NHLBI NIH HHS/ -- New York, N.Y. -- Science. 1984 Jan 20;223(4633):249-55.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/6322295" target="_blank"〉PubMed〈/a〉
    Keywords: Amino Acid Sequence ; Apolipoprotein A-I ; Apolipoproteins ; Binding Sites ; Calcitonin ; Chemical Phenomena ; Chemistry ; Corticotropin-Releasing Hormone ; Endorphins ; Glucagon ; Growth Hormone-Releasing Hormone ; *Hormones/pharmacology ; Lipoproteins, HDL ; Melitten ; Models, Structural ; *Peptides/chemical synthesis/metabolism/pharmacology ; Protein Conformation ; Structure-Activity Relationship ; beta-Endorphin
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  • 7
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    Fourier transform mass spectrometry (1984)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1984-10-19
    Description: Fourier transform mass spectrometry will play an important role in the future because of its unique combination of high mass resolution, high upper mass limit, and multichannel advantage. These features have already found application in gas chromatography-mass spectrometry, multiphoton ionization, laser desorption, and secondary ion mass spectrometry. However, its most notable feature is the ability to store ions. This characteristic, when combined with the others, will allow expeditious study of the interaction of gas-phase ions with both photons (photodissociation) and neutral molecules, and the convenient application of this fundamental information for chemical analysis.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Gross, M L -- Rempel, D L -- 2-8423576/PHS HHS/ -- New York, N.Y. -- Science. 1984 Oct 19;226(4672):261-8.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/6385250" target="_blank"〉PubMed〈/a〉
    Keywords: Chemical Phenomena ; Chemistry ; *Fourier Analysis ; Ions ; Lasers ; *Mass Spectrometry/instrumentation/methods
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  • 8
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    Studying enzyme mechanism by 13C nuclear magnetic resonance (1984)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1984-08-31
    Description: High-resolution carbon-13 nuclear magnetic resonance (NMR) spectra of enzyme-inhibitor and enzyme-substrate complexes provide detailed structural and stereochemical information on the mechanism of enzyme action. The proteases trypsin and papain are shown to form tetrahedrally coordinated complexes and acyl derivatives with a variety of compounds artificially enriched at the site or sites of interest. These results are compared with the structural information derived from x-ray diffraction. Detailed NMR studies have provided a clearer picture of the ionization state of the residues participating in enzyme-catalyzed processes than other more classical techniques. The dynamics of enzymic catalysis can be observed at sub-zero temperatures by a combination of cryoenzymology and carbon-13 NMR spectroscopy. With these powerful techniques, transient, covalently bound intermediates in enzyme-catalyzed reactions can be detected and their structures rigorously assigned.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Mackenzie, N E -- Malthouse, J P -- Scott, A I -- New York, N.Y. -- Science. 1984 Aug 31;225(4665):883-9.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/6433481" target="_blank"〉PubMed〈/a〉
    Keywords: Binding Sites ; Carbon Isotopes ; Carboxypeptidases/metabolism ; Carboxypeptidases A ; Catalysis ; Chemical Phenomena ; Chemistry ; Coenzymes/*metabolism ; Endopeptidases/metabolism ; Enzymes/*metabolism ; Freezing ; Fructose-Bisphosphate Aldolase/metabolism ; Magnetic Resonance Spectroscopy ; Papain/metabolism ; Pepsin A/metabolism ; Peptide Hydrolases/*metabolism ; Protease Inhibitors ; Pterins/metabolism ; Pyridoxal Phosphate/metabolism ; Serine Endopeptidases
    Print ISSN: 0036-8075
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  • 9
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    What is the risk from chlorofluorocarbons? (1984)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1984-03-09
    Description: 〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Maugh, T H 2nd -- New York, N.Y. -- Science. 1984 Mar 9;223(4640):1051-2.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/6695193" target="_blank"〉PubMed〈/a〉
    Keywords: *Air Pollutants ; *Atmosphere ; Carbon Tetrachloride ; Chemical Phenomena ; Chemistry ; *Chlorofluorocarbons, Methane ; Free Radicals ; Nitrogen Dioxide ; Nitrous Oxide ; Oxygen ; *Ozone ; Photochemistry ; Risk ; Singlet Oxygen ; Trichloroethanes ; Ultraviolet Rays
    Print ISSN: 0036-8075
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    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
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  • 10
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    Pyrolysis mass spectrometry of complex organic materials (1984)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1984-10-19
    Description: Pyrolysis mass spectrometry in combination with computerized multivariate statistical analysis enables qualitative and quantitative analysis of nonvolatile organic materials containing molecular assemblies of a complexity and size far beyond the capabilities of direct mass spectrometry. The state of the art in pyrolysis mass spectrometry techniques is illustrated through specific applications, including structural determination and quality control of synthetic polymers, quantitative analysis of polymer mixtures, classification and structural characterization of fossil organic matter, and nonsupervised numerical extraction of component patterns from complex biological samples.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Meuzelaar, H L -- Windig, W -- Harper, A M -- Huff, S M -- McClennen, W H -- Richards, J M -- New York, N.Y. -- Science. 1984 Oct 19;226(4672):268-74.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/6484572" target="_blank"〉PubMed〈/a〉
    Keywords: Biochemical Phenomena ; Biochemistry ; Chemical Phenomena ; Chemistry ; Coal ; Enterobacteriaceae/analysis/isolation & purification ; Hot Temperature ; Mass Spectrometry/*methods ; Polymers
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  • 11
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    Lariat RNA's as intermediates and products in the splicing of messenger RNA precursors (1984)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1984-08-31
    Description: The splicing of messenger RNA precursors in vitro proceeds through an intermediate that has the 5' end of the intervening sequence joined to a site near the 3' splice site. This lariat structure, which has been characterized for an adenovirus 2 major late transcript, has a branch point, with 2'-5' and 3'-5' phosphodiester bonds emanating from a single adenosine residue. The excised intervening sequence retains the branch site and terminates in a guanosine residue with a 3' hydroxyl group. The phosphate group at the splice junction between the two exons originates from the 3' splice site at the precursor.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Padgett, R A -- Konarska, M M -- Grabowski, P J -- Hardy, S F -- Sharp, P A -- P01-CA14051/CA/NCI NIH HHS/ -- P01-CA26717/CA/NCI NIH HHS/ -- R01-GM32467/GM/NIGMS NIH HHS/ -- New York, N.Y. -- Science. 1984 Aug 31;225(4665):898-903.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/6206566" target="_blank"〉PubMed〈/a〉
    Keywords: Adenoviruses, Human/metabolism ; Base Sequence ; Chemical Phenomena ; Chemistry ; Nucleic Acid Conformation ; Nucleic Acid Precursors/analysis/*metabolism ; Oligoribonucleotides/metabolism ; Phosphates/metabolism ; RNA/analysis/*metabolism ; RNA Precursors ; *RNA Splicing ; RNA, Messenger/analysis/*metabolism ; RNA, Viral/analysis/*metabolism
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  • 12
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    beta-Carotene: an unusual type of lipid antioxidant (1984)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1984-05-11
    Description: The mechanism of lipid peroxidation and the manner in which antioxidants function is reviewed. beta-Carotene is a purported anticancer agent, which is believed by some to have antioxidant action of a radical-trapping type. However, definitive experimental support for such action has been lacking. New experiments in vitro show that beta-carotene belongs to a previously unknown class of biological antioxidants. Specifically, it exhibits good radical-trapping antioxidant behavior only at partial pressures of oxygen significantly less than 150 torr, the pressure of oxygen in normal air. Such low oxygen partial pressures are found in most tissues under physiological conditions. At higher oxygen pressures, beta-carotene loses its antioxidant activity and shows an autocatalytic, prooxidant effect, particularly at relatively high concentrations. Similar oxygen-pressure-dependent behavior may be shown by other compounds containing many conjugated double bonds.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Burton, G W -- Ingold, K U -- New York, N.Y. -- Science. 1984 May 11;224(4649):569-73.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/6710156" target="_blank"〉PubMed〈/a〉
    Keywords: Antioxidants/*metabolism ; Carotenoids/*metabolism ; Chemical Phenomena ; Chemistry ; Free Radicals ; Humans ; Linoleic Acids/metabolism ; *Lipid Metabolism ; Oxidation-Reduction ; Oxygen/metabolism ; Partial Pressure ; Peroxides/metabolism ; Tetrahydronaphthalenes/metabolism ; beta Carotene
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  • 13
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    Bromine residue at hydrophilic region influences biological activity of aplysiatoxin, a tumor promoter (1983)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1983-12-16
    Description: Aplysiatoxin and debromoaplysiatoxin, which are isolated from the seaweed, Lyngbya gracilis, differ in their chemical structure only by the presence or absence of a bromine residue in the hydrophilic region. The function and the structure-activity relation of the hydrophilic region are not known. Aplysiatoxin increased malignant transformation, stimulated DNA synthesis, and inhibited the binding of phorbol-12,13-dibutyrate and epidermal growth factor to cell receptors. Debromoaplysiatoxin inhibited the binding of these two substances as strongly as aplysiatoxin but did not increase malignant transformation or stimulate DNA synthesis. These results indicate that a slight change in the chemical structure of the hydrophilic region of aplysiatoxin affects its abilities to increase cell transformation and stimulate DNA synthesis and that the abilities of the tumor promoters to inhibit the binding of phorbol-12,13-dibutyrate and epidermal growth factor are dissociable from their abilities to increase cell transformation and stimulate DNA synthesis under some circumstances.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Shimomura, K -- Mullinix, M G -- Kakunaga, T -- Fujiki, H -- Sugimura, T -- New York, N.Y. -- Science. 1983 Dec 16;222(4629):1242-4.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/6316505" target="_blank"〉PubMed〈/a〉
    Keywords: Animals ; *Caenorhabditis elegans Proteins ; Carcinogens/*pharmacology ; Carrier Proteins ; Cell Line ; Cell Transformation, Neoplastic/*drug effects ; Chemical Phenomena ; Chemistry ; DNA/biosynthesis ; Epidermal Growth Factor/metabolism ; Lactones/analysis/*pharmacology ; *Lyngbya Toxins ; Mice ; Phorbol 12,13-Dibutyrate ; Phorbol Esters/metabolism ; *Protein Kinase C ; Receptor, Epidermal Growth Factor ; Receptors, Cell Surface/metabolism ; *Receptors, Drug ; Structure-Activity Relationship
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  • 14
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    Phenylalanine transfer RNA: molecular dynamics simulation (1984)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1984-03-16
    Description: Yeast phenylalanine transfer RNA was subjected to a 12-picosecond molecular dynamics simulation. The principal features of the x-ray crystallographic analysis are reproduced, and the amplitudes of atomic displacements appear to be determined by the degree of exposure of the atoms. An analysis of the hydrogen bonds shows a correlation between the average length of a bond and the fluctuation in that length and reveals a rocking motion of bases in Watson-Crick guanine X cytosine base pairs. The in-plane motions of the bases are generally of larger amplitude than the out-of-plane motions, and there are correlations in the motions of adjacent bases.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Harvey, S C -- Prabhakaran, M -- Mao, B -- McCammon, J A -- New York, N.Y. -- Science. 1984 Mar 16;223(4641):1189-91.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/6560785" target="_blank"〉PubMed〈/a〉
    Keywords: Chemical Phenomena ; Chemistry ; Computers ; Cytosine ; Guanine ; Hydrogen Bonding ; Nucleic Acid Conformation ; *RNA, Fungal ; *RNA, Transfer, Amino Acyl ; Yeasts/analysis
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  • 15
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    Reaction of the antitumor antibiotic CC-1065 with DNA: structure of a DNA adduct with DNA sequence specificity (1984)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1984-11-16
    Description: Sequence-dependent variations in DNA revealed by x-ray crystallographic studies have suggested that certain DNA-reactive drugs may react preferentially with defined sequences in DNA. Drugs that wind around the helix and reside within one of the grooves of DNA have perhaps the greatest chance of recognizing sequence-dependent features of DNA. The antitumor antibiotic CC-1065 covalently binds through N-3 of adenine and resides within the minor groove of DNA. This drug overlaps with five base pairs for which a high sequence specificity exists.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Hurley, L H -- Reynolds, V L -- Swenson, D H -- Petzold, G L -- Scahill, T A -- New York, N.Y. -- Science. 1984 Nov 16;226(4676):843-4.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/6494915" target="_blank"〉PubMed〈/a〉
    Keywords: Antibiotics, Antineoplastic/*metabolism ; *Base Sequence ; Binding Sites ; Chemical Phenomena ; Chemistry ; DNA/*metabolism ; *Indoles ; Leucomycins/*metabolism ; Molecular Conformation ; X-Ray Diffraction
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  • 16
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    Allylamine derivatives: new class of synthetic antifungal agents inhibiting fungal squalene epoxidase (1984)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1984-06-15
    Description: A new class of synthetic antifungal agents, the allylamines , has been developed by modification of naftifine , a topical antimycotic. SF 86-327, the most effective of these compounds so far, is highly active in vitro against a wide range of fungi and exceeds clinical standards in the oral and topical treatment of guinea pig dermatophytoses. SF 86-327 is a powerful specific inhibitor of fungal squalene epoxidase, a key enzyme in sterol biosynthesis.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Petranyi, G -- Ryder, N S -- Stutz, A -- New York, N.Y. -- Science. 1984 Jun 15;224(4654):1239-41.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/6547247" target="_blank"〉PubMed〈/a〉
    Keywords: Allylamine/analogs & derivatives/*chemical synthesis/pharmacology ; Amines/*chemical synthesis ; Animals ; Antifungal Agents/*chemical synthesis/pharmacology ; Chemical Phenomena ; Chemistry ; Dermatomycoses/drug therapy ; Fungi/*drug effects/enzymology ; Guinea Pigs ; Naphthalenes/chemical synthesis/pharmacology ; Oxygenases/*antagonists & inhibitors ; Squalene Monooxygenase
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    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
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    Disulfide bond engineered into T4 lysozyme: stabilization of the protein toward thermal inactivation (1984)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1984-11-02
    Description: By recombinant DNA techniques, a disulfide bond was introduced at a specific site in T4 lysozyme, a disulfide-free enzyme. This derivative retained full enzymatic activity and was more stable toward thermal inactivation than the wild-type protein. The derivative, T4 lysozyme (Ile3----Cys), was prepared by substituting a Cys codon for an Ile codon at position 3 in the cloned lysozyme gene by means of oligonucleotide-dependent, site-directed mutagenesis. The new gene was expressed in Escherichia coli under control of the (trp-lac) hybrid tac promoter, and the protein was purified. Mild oxidation generated a disulfide bond between the new Cys3 and Cys97, one of the two unpaired cysteines of the native molecule. Oxidized T4 lysozyme (Ile3----Cys) exhibited specific activity identical to that of the wild-type enzyme when measured at 20 degrees C in a cell-clearing assay. The cross-linked protein was more stable than the wild type during incubation at elevated temperatures as determined by recovered enzymatic activity at 20 degrees C.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Perry, L J -- Wetzel, R -- New York, N.Y. -- Science. 1984 Nov 2;226(4674):555-7.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/6387910" target="_blank"〉PubMed〈/a〉
    Keywords: Chemical Phenomena ; Chemistry ; DNA, Recombinant/metabolism ; Escherichia coli/enzymology ; *Genetic Engineering ; Kinetics ; Muramidase/*genetics/metabolism ; Protein Denaturation
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  • 18
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    DNA-binding proteins (1983)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1983-09-09
    Description: The structures of three proteins that regulate gene expression have been determined recently and suggest how these proteins may bind to their specific recognition sites on the DNA. One protein (Cro) is a repressor of gene expression, the second (CAP) usually stimulates gene expression, and the third (lambda repressor) can act as either a repressor or an activator. The three proteins contain a substructure consisting of two consecutive alpha helices that is virtually identical in each case. Structural and amino acid sequence comparisons suggest that this bihelical fold occurs in a number of proteins that regulate gene expression, and is an intrinsic part of the DNA-protein recognition event. The modes of repression and activation by Cro and lambda repressor are understood reasonably well, but the mode of action of CAP is still unclear.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Takeda, Y -- Ohlendorf, D H -- Anderson, W F -- Matthews, B W -- GM20066/GM/NIGMS NIH HHS/ -- GM28138/GM/NIGMS NIH HHS/ -- GM30894/GM/NIGMS NIH HHS/ -- New York, N.Y. -- Science. 1983 Sep 9;221(4615):1020-6.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/6308768" target="_blank"〉PubMed〈/a〉
    Keywords: Amino Acid Sequence ; Chemical Phenomena ; Chemistry ; *DNA Helicases ; DNA-Binding Proteins ; Escherichia coli/genetics ; Gene Expression Regulation ; Models, Chemical ; Protein Conformation
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  • 19
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    A nitrogen pressure of 50 atmospheres does not prevent evolution of hydrogen by nitrogenase (1984)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1984-06-08
    Description: The effect of a partial pressure of nitrogen of 50 atmospheres (5065 kilopascals ) on the hydrogen evolution reaction of nitrogenase has been investigated. Evolution of hydrogen was not blocked completely by 50 atmospheres of nitrogen in any of four experiments; rather, 27.3 +/- 2.4 percent of the total electron flux through nitrogenase was directed toward production of hydrogen. The ratio of hydrogen evolved to nitrogen fixed was close to 1:1, which implies that hydrogen evolution is obligatory in the fixation of molecular nitrogen by nitrogenase.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Simpson, F B -- Burris, R H -- AI-00848/AI/NIAID NIH HHS/ -- New York, N.Y. -- Science. 1984 Jun 8;224(4653):1095-7.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/6585956" target="_blank"〉PubMed〈/a〉
    Keywords: Chemical Phenomena ; Chemistry ; *Hydrogen ; *Nitrogen ; Nitrogen Fixation ; *Nitrogenase ; Partial Pressure
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  • 20
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    Nonvolatile mutagens in drinking water: production by chlorination and destruction by sulfite (1980)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1980-01-04
    Description: In concentrates of water produced in a laboratory simulation of a drinking water treatment process, direct-acting, nonvolatile mutagens were readily detected by means of the Ames Salmonella test. The mutagens were shown to be produced by the chlorination process. Treatment of the water with chloramine resulted in less mutagenic activity than treatment with free chlorine. Dechlorination of drinking water with sulfite sharply reduced the mutagenic activity. Treatment with sulfur dioxide is proposed as an effective, inexpensive method of reducing the direct-acting mutagenic activity of drinking water and of aqueous industrial effluents.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Cheh, A M -- Skochdopole, J -- Koski, P -- Cole, L -- New York, N.Y. -- Science. 1980 Jan 4;207(4426):90-2.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/6985746" target="_blank"〉PubMed〈/a〉
    Keywords: Chemical Phenomena ; Chemistry ; Chloramines ; Chlorine ; Mutagens/*analysis ; Salmonella typhimurium/genetics ; Sulfites ; Water Pollutants/*analysis ; Water Pollutants, Chemical/*analysis ; Water Supply/*analysis
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  • 21
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    Automated synthesis of gene fragments (1981)
    American Association for the Advancement of Science (AAAS)
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    Publication Date: 1981-10-16
    Description: The DNA/RNA Synthesizer provides a complete and automated procedure for the synthesis of DNA sequences. Each base unit is added in a 30-minute cycle, permitting a tetradecamer to be constructed in 6 1/2 hours. The complete procedure is described, including a practical procedure for isolation and purification of the desired DNA sequence.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Alvarado-Urbina, G -- Sathe, G M -- Liu, W C -- Gillen, M F -- Duck, P D -- Bender, R -- Ogilvie, K K -- New York, N.Y. -- Science. 1981 Oct 16;214(4518):270-4.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/6169150" target="_blank"〉PubMed〈/a〉
    Keywords: Automation ; Chemical Phenomena ; Chemistry ; DNA/*chemical synthesis ; *Genes, Synthetic ; RNA/*chemical synthesis ; Solubility
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  • 22
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    Chitin: New facets of research (1981)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1981-05-15
    Description: Research on chitin as a marine resource is pointing to novel applications for this cellulose-like biopolymer. Discovery of nondegrading solvent systems has permitted the spinning of filaments, for example, for use as surgical sutures. New methods for preparing the bioactive alkyl glycoside of N-acetyl-D-glucosamine (the monomer unit of chitin) and a microcrystalline chitin has encouraged their use as promoters for growth of bifidobacteria and as an aid in digestion of high-lactose cheese whey by domestic animals. Chitin-protein complexes of several crustacean species show great variability in ratios of chitin to covalently bound protein and in residual protein in the "purified" chitins.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Austin, P R -- Brine, C J -- Castle, J E -- Zikakis, J P -- New York, N.Y. -- Science. 1981 May 15;212(4496):749-53.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/7221561" target="_blank"〉PubMed〈/a〉
    Keywords: Animal Feed ; Animals ; Cheese ; Chemical Phenomena ; Chemistry ; Chickens ; *Chitin ; Crystallography ; Lactose/metabolism ; Proteins/analysis ; Sutures ; *Technology
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  • 23
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    DNA sequencing and gene structure (1981)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1981-12-18
    Description: 〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Gilbert, W -- New York, N.Y. -- Science. 1981 Dec 18;214(4527):1305-12.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/7313687" target="_blank"〉PubMed〈/a〉
    Keywords: Base Sequence ; Chemical Phenomena ; Chemistry ; DNA/*genetics ; Eukaryotic Cells/physiology ; *Genes ; Hydrazines ; Lac Operon ; Methylation ; Prokaryotic Cells/physiology ; Sulfuric Acid Esters
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  • 24
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    Boradeption: a new procedure for transferring water-insoluble agents across cell membranes (1982)
    American Association for the Advancement of Science (AAAS)
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    Publication Date: 1982-07-09
    Description: A new process has been developed which is called "Boradeption" to signify boronic acid--dependent phase transfer of water-insoluble agents. Highly fluorescent boronic acid dervatives, FluoroBoras, are solubilized with a physiologically compatible carrier buffer containing a receptor group for boronate adduct formation. The system can be used to stain living cells. In another variation of the Boradeption concept, an insoluble reporter molecule containing a boronate receptor is solubilized with a carrier buffer containing a boronic acid functional group. The boronate-receptor complexes, which are in dynamic equilibrium, can be designed as vital stains and reagents for a variety of biological and medical applications.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Gallop, P M -- Paz, M A -- Henson, E -- AG-00376-07/AG/NIA NIH HHS/ -- HL-20764-04A1/HL/NHLBI NIH HHS/ -- New York, N.Y. -- Science. 1982 Jul 9;217(4555):166-9.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/6178158" target="_blank"〉PubMed〈/a〉
    Keywords: Animals ; *Biological Transport ; *Boron Compounds/therapeutic use ; *Boronic Acids/therapeutic use ; *Cell Membrane Permeability ; Cells, Cultured ; Chemical Phenomena ; Chemistry ; Chromogenic Compounds/metabolism ; Cricetinae ; Fibroblasts ; Fluorescent Dyes/metabolism ; Humans ; Rats ; Staining and Labeling
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    Reversible chemical modification of the scrapie agent (1981)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1981-12-11
    Description: The scrapie agent causes a degenerative nervous system disease in sheep and goats. Studies with extensively purified preparations demonstrated that the agent contains a protein that is required for infectivity. Chemical modification of the scrapie agent by diethyl pyrocarbonate reduced the titer 1000-fold. Exposure of the inactivated agent to hydroxylamine, a strong nucleophile, resulted in complete restoration of infectivity. Presumably, nucleophilic residues within a scrapie agent protein undergo carbethoxylation on reaction with diethyl pyrocarbonate, and subsequent addition of hydroxylamine displaces these carbethoxy groups.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉McKinley, M P -- Masiarz, F R -- Prusiner, S B -- NS14069/NS/NINDS NIH HHS/ -- New York, N.Y. -- Science. 1981 Dec 11;214(4526):1259-61.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/6795721" target="_blank"〉PubMed〈/a〉
    Keywords: Animals ; Biological Assay ; Brain/microbiology ; Chemical Phenomena ; Chemistry ; Cricetinae ; Diethyl Pyrocarbonate/pharmacology ; Histidine/pharmacology ; *Prions ; Ribonucleases/pharmacology ; Serum Albumin, Bovine/pharmacology ; Viral Proteins/*isolation & purification/pharmacology
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    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
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  • 26
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    Nonenzymatic browning in vivo: possible process for aging of long-lived proteins (1981)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1981-01-30
    Description: The incubation of lens proteins with reducing sugars leads to the formation of fluorescent yellow pigments and cross-like similar to those reported in aging and cataractous human lenses. Called nonenzymatic browning or the Maillard reaction, this aging process also occurs in stored foods. Reducing sugars condense with the free amino group of proteins, then rearrange and dehydrate to form unsaturated pigments and cross-linked products. Although most proteins in living systems turn over with sufficient rapidity to avoid nonenzymatic browning, some, such as lens crystallins and skin collagen, are exceptionally long-lived and may be vulnerable.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Monnier, V M -- Cerami, A -- AM 19655/AM/NIADDK NIH HHS/ -- New York, N.Y. -- Science. 1981 Jan 30;211(4481):491-3.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/6779377" target="_blank"〉PubMed〈/a〉
    Keywords: *Aging ; Animals ; Cattle ; Chemical Phenomena ; Chemistry ; *Crystallins ; Diabetes Mellitus/physiopathology ; Glucose ; Glucosephosphates ; In Vitro Techniques ; Lysine ; *Proteins ; Spectrophotometry, Ultraviolet
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    The National Science Foundation looks to the future (1981)
    American Association for the Advancement of Science (AAAS)
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    Publication Date: 1981-03-13
    Description: Great advances have been made in fundamental scientific research in recent years. The new knowledge gathered, in addition to deepening our understanding of the physical universe, contributes a range of abilities and opportunities to society that would not otherwise be available. Much research that may be called applied because it addresses needs of society is quite fundamental in character, and support of such research at the National Science Foundation is to be handled in tandem by the research directorates. Other areas that require a refocusing of support are engineering science and education, at all levels, in science and engineering. Increasing our strength in these areas is essential to achieve our national economic, social, and political goals. Steps are being taken by the National Science Foundation to make its structure better able to deal with engineering and applied research and to provide greater mutual reinforcement between applied and basic research.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Slaughter, J B -- New York, N.Y. -- Science. 1981 Mar 13;211(4487):1131-6.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/7466384" target="_blank"〉PubMed〈/a〉
    Keywords: Cell Biology ; Chemical Phenomena ; Chemistry ; *Forecasting ; Geological Phenomena ; Geology ; *Government Agencies ; Molecular Biology ; Neurochemistry ; Physical Phenomena ; Physics ; Research Support as Topic ; United States
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  • 28
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    New chemistry of an old molecule: cis-[Pt(NH3)2Cl2] (1982)
    American Association for the Advancement of Science (AAAS)
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    Publication Date: 1982-12-10
    Description: The discovery that cis-diamminedichloroplatinum(II) (cis-DDP) has clinically useful antitumor properties and can form platinum blues spawned an extensive investigation of its chemistry in water. Several new molecules have been synthesized, some rather old ones have been characterized for the first time, and clues have begun to emerge about the chemical interaction of cis-DDP with its likely biological target, DNA.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Lippard, S J -- New York, N.Y. -- Science. 1982 Dec 10;218(4577):1075-82.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/6890712" target="_blank"〉PubMed〈/a〉
    Keywords: Chemical Phenomena ; Chemistry ; *Cisplatin ; *Dna ; Hydrolysis ; Pigments, Biological
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  • 29
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    The chemistry of vision (1982)
    American Association for the Advancement of Science (AAAS)
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    Publication Date: 1982-12-03
    Description: The visual response is initiated by light reception and transduction into chemical and electrical energy in the outer-segment membranes of rod and cone cells. Recent research on the molecular events controlled by light has clarified the roles of some of the rod outer-segment biomolecules. These developments and the current unresolved questions are described.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉O'Brien, D F -- New York, N.Y. -- Science. 1982 Dec 3;218(4576):961-6.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/6291153" target="_blank"〉PubMed〈/a〉
    Keywords: Animals ; Blood Proteins/metabolism ; Calcium/metabolism ; Chemical Phenomena ; Chemistry ; Enzyme Activation ; Enzymes/metabolism ; GTP-Binding Proteins ; Light ; Membranes/metabolism ; Models, Biological ; Phosphoric Diester Hydrolases/biosynthesis ; Photoreceptor Cells/*metabolism ; Receptors, Cell Surface/metabolism ; Rhodopsin/metabolism ; Rod Cell Outer Segment/*metabolism ; Vision, Ocular/*physiology
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  • 30
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    Antiviral agents (1983)
    American Association for the Advancement of Science (AAAS)
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    Publication Date: 1983-06-10
    Description: 〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Krenitsky, T A -- Beauchamp, L -- New York, N.Y. -- Science. 1983 Jun 10;220(4602):1106.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/6857236" target="_blank"〉PubMed〈/a〉
    Keywords: Acyclovir/metabolism ; *Antiviral Agents/metabolism ; Chemical Phenomena ; Chemistry ; Humans ; Vidarabine/metabolism
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  • 31
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    Metastable species of hemoglobin: room temperature transients and cryogenically trapped intermediates (1983)
    American Association for the Advancement of Science (AAAS)
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    Publication Date: 1983-05-06
    Description: Resonance Raman spectra of photolyzed carbonmonoxyhemoglobin obtained with 10-nanosecond pulses are compared with the spectra of photolyzed carbonmonoxyhemoglobin stabilized at 80 K. In comparing the deoxy with the photodissociated species, the changes in the Raman spectra are the same for these two experimental regimes. These results show that at ambient and cryogenic temperatures the heme pocket in liganded hemoglobin is significantly different from that of deoxyhemoglobin. It is concluded that measurements of the properties of intermediate species from photodissociated hemoglobin stabilized at low temperatures can be used to probe the short-lived metastable forms of hemoglobin present after photodissociation under biologically relevant solution conditions.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Ondrias, M R -- Friedman, J M -- Rousseau, D L -- New York, N.Y. -- Science. 1983 May 6;220(4597):615-7.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/6836305" target="_blank"〉PubMed〈/a〉
    Keywords: Carboxyhemoglobin ; Chemical Phenomena ; Chemistry ; Freezing ; *Hemoglobins ; Humans ; Ligands ; Spectrum Analysis, Raman ; Temperature
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  • 32
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    Irreversible ligands with high selectivity toward delta and mu opiate receptors (1983)
    American Association for the Advancement of Science (AAAS)
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    Publication Date: 1983-04-15
    Description: Alkylating agents that display strong selectivity for opiate receptor types delta or mu were prepared by appropriate modification of the structures of the strong analgesics fentanyl, etonitazene, and endoethenotetrahydrooripavine. The availability of these substances should facilitate studies of the structural basis of receptor specificity and of the physiologic roles of these receptors.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Rice, K C -- Jacobson, A E -- Burke, T R Jr -- Bajwa, B S -- Streaty, R A -- Klee, W A -- New York, N.Y. -- Science. 1983 Apr 15;220(4594):314-6.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/6132444" target="_blank"〉PubMed〈/a〉
    Keywords: Alkylation ; Animals ; Benzimidazoles/analogs & derivatives/metabolism ; Brain/physiology ; Cells, Cultured ; Chemical Phenomena ; Chemistry ; Enkephalin, Methionine/analogs & derivatives/metabolism ; Fentanyl/analogs & derivatives/metabolism ; *Isothiocyanates ; Ligands ; Rats ; Receptors, Opioid/*metabolism/physiology ; Thebaine/analogs & derivatives/pharmacology
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  • 33
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    Trace chemistries of fire: a source of chlorinated dioxins (1980)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1980-10-01
    Description: 〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Bumb, R R -- Crummett, W B -- Cutie, S S -- Gledhill, J R -- Hummel, R H -- Kagel, R O -- Lamparski, L L -- Luoma, E V -- Miller, D L -- Nestrick, T J -- Shadoff, L A -- Stehl, R H -- Woods, J S -- New York, N.Y. -- Science. 1980 Oct;210(4468):385-90.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/6159682" target="_blank"〉PubMed〈/a〉
    Keywords: Air Pollutants/analysis ; Chemical Phenomena ; Chemistry ; Chromatography, High Pressure Liquid ; *Dioxins/analysis ; *Fires ; Power Plants ; Smoke/analysis ; Soil Pollutants/analysis ; Tetrachlorodibenzodioxin/analysis ; Vehicle Emissions/analysis ; Water Pollutants, Chemical/analysis
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
    Published by American Association for the Advancement of Science (AAAS)
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  • 34
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    Synthetic competitive antagonists of corticotropin-releasing factor: effect on ACTH secretion in the rat (1984)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1984-05-25
    Description: Polypeptide analogs of the known members of the corticotropin-releasing factor (CRF) family were synthesized and tested in vitro and in vivo for enhanced potency or competitive antagonism. Predictive methods and physicochemical measurements had suggested an internal secondary alpha-helical conformation spanning about 25 residues for at least three members of the CRF family. Maximization of alpha-helix-forming potential by amino acid substitutions from the native known sequences (rat/human and ovine CRF, sauvagine, and carp and sucker urotensin 1) led to the synthesis of an analog that was found to be more than twice as potent as either of the parent peptides in vitro. In contrast, certain amino-terminally shortened fragments, such as alpha-helical CRF or ovine CRF residues 8 to 41, 9 to 41, and 10 to 41, were found to be competitive inhibitors in vitro. Selected antagonists were examined and also found to be active in vivo.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Rivier, J -- Rivier, C -- Vale, W -- AA03504/AA/NIAAA NIH HHS/ -- AM20917/AM/NIADDK NIH HHS/ -- AM26741/AM/NIADDK NIH HHS/ -- etc. -- New York, N.Y. -- Science. 1984 May 25;224(4651):889-91.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/6326264" target="_blank"〉PubMed〈/a〉
    Keywords: Adrenocorticotropic Hormone/secretion ; Animals ; Binding, Competitive ; Chemical Phenomena ; Chemistry ; Corticotropin-Releasing Hormone/*antagonists & inhibitors ; Rats
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
    Published by American Association for the Advancement of Science (AAAS)
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  • 35
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    Other groundbased observations (1995)
    In:  Other Sources
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    Publication Date: 2011-08-24
    Description: Ground-based solar observational programs are discussed. The Birmingham (U.K.) solar oscillation network (BiSON) program, the Crimean (Ukraine) low degree program, the Stanford (California) low degree program, the Tenerife (Spain) group program, the South Pole program, the Mount Wilson (California) program, the international research on the interior of the sun (IRIS) network program, the high-l helioseismometer instrument, the ground luminosity oscillations imager (LOI) program, and the Taiwanese oscillation network (TON) program, are outlined.
    Keywords: ASTRONOMY
    Type: ESA, Proceedings of 4th SOHO on Helioseismology. Volume 1: Invited Reviews and Working Group Reports; p 107-111
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  • 36
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    Another look at the UBV variability of T Tauri stars (1995)
    In:  Other Sources
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    Publication Date: 2011-08-24
    Description: The UBV variability of classical T Tauri stars is investigated using a large data set compiled by Herbst et al. (1994). The analysis is based on the covariance of the UBV colors, which is independent of the obscuration and the temporal sampling, and is a powerful tool for finding trends that otherwise would be hidden in the complex time-dependence of the data. I find that there are two types of UBV variability and introduce the nomenclature 'ortho-' and 'para-UBV' variations, or in short 'type-O' and 'type-P' variations. Objects with a predominance of ortho-UBV variability show strong variability in both the Balmer and Paschen continua, whereas objects dominated by para-UBV changes vary mostly in the Paschen continuum. I show that type-O variations can be explained in terms of rotating spots, variable obscuration, or changes intrinsic to the source that obey the law Delta T(sub S)/T(sub S) varies as Delta n(sub H)/n(sub H), where T(sub S) and n(sub H) are, respectively, the gas temperature and the number density of hydrogen nuclei. Type-P variations can be explained only by changes intrinsic to the source with Delta T(sub S)/T(sub S) varies as - Delta n(sub H)/n(sub H), and I speculate on a possible origin for these changes. The covariance ellipse of the UBV colors is a versatile tool for studying the connection between variability and other spectral signatures of classical T Tauri stars; its use for this purpose is illustrated by studying the correlation between the presence of CO first-overtone bands in emission and the type of variability. I find that objects with CO band emission are also those with type-P variability and propose an observational test to validate this conclusion.
    Keywords: ASTRONOMY
    Type: Astrophysical Journal, Part 1 (ISSN 0004-637X); 444; 2; p. 818-830
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  • 37
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    The local metallicity-surface brightness relationship in galactic disks (1995)
    In:  Other Sources
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    Publication Date: 2011-08-24
    Description: We present the results of a first attempt to employ multiaperture masks to obtain spectrophotometry of H II regions in nearby galaxies. A total of 97 H II regions in six southern spiral galaxies were observed using a combination of multiaperture masks and conventional long-slit spectrophotometry. The oxygen abundances derived from the multiaperture mask observations using the empirical abundance diagnostic R(sub 23) are shown to be consistent with those from long-slit spectra and generally show better reproducibility and object definition. Although the number of objects that can be observed simultaneously with this particular system is still quite limited compared with either imaging spectrophotometry or fiber-fed spectrographs, the spectral resolution offered and high throughput in the blue help make multiaperture spectrophotometry a competitive technique for increasing the sampling of H II regions in both radial distance and luminosity. There is still no clear trend of abundance gradient with either the galaxy's luminosity or its Hubble type, although the extrapolated central abundance does appear to correlate with galaxy luminosity/mass. In order to avoid difficulty in choosing an appropriate normalizing radius, we instead plot the oxygen abundance against the underlying I-band surface brightness at the radial distance of the H II region and confirm the existence of a local metallicity-surface brightness reltaionship within the disks of spiral galaxies. Although the simple closed-boc model of galaxy evolution predicts almost the right form of this relationship, a more realistic multizone model employing expnentially decreasing gas infall provides a more satisfactory fit to the observational data, provided the expected enriched gas return from dying low-mass stars shedding their envelopes at late epochs is properly taken into account. This same model, with a star formation law based upon self-regulating star formation in a three-dimensional disk (Dopita & Ryder 1994), is equally capable of accounting for the observed relationship between recent massive star formation and stellar surface brightness (Ryder & Dopita 1994).
    Keywords: ASTRONOMY
    Type: Astrophysical Journal, Part 1 (ISSN 0004-637X); 444; 2; p. 610-631
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  • 38
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    The unusual morphology of molecular hydrogen emission in the planetary nebula J900 (1995)
    In:  Other Sources
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    Publication Date: 2011-08-24
    Description: We report new high-resolution near-infrared imaging observations of the planetary nebula J900, in broadband J, H, and K, and narrowband 2.122 micrometers (for H2 1-0 S(1)), Brackett-gamma, and continuum filters. The H2 images reveal a remarkable set of outward-extending features not detected in any previous observations of theis object. In the northwest lobe of the inner bipolar region, the H2 emission, Brackett-gamma emission, and underlying continuum are spatially resolved. The relative positions of the peaks of the line emission suggest an ionization front seen edge-on. The continuum emission, apparently located nearer to the central star, is likely due to transiently heated small dust grains. The extended H2 emission features are probably excited either by oblique shocks caused by material ejected from the nebula, or by radiation leaking from holes in the opacity surrounding the ionized shell.
    Keywords: ASTRONOMY
    Type: Astronomical Journal (ISSN 0004-6256); 109; 3; p. 1173-1180
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  • 39
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    First detection of x-ray variability of eta carinae (1995)
    In:  Other Sources
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    Publication Date: 2011-08-24
    Description: Recent ROSAT Position Sensitive Proportional Counter (PSPC) observations for the first time unequivocally reveal the presence of a compact source of hard X-ray emission centered on the peculiar star eta Car. These observations also show a dramatic change in the hard-band (E greater than 1.6 keV) counting rate by about a factor of 2 in a 4 month interval. Thus, strong variability, which is a characteristic of eta Car in radio through IR and visible-band wavelengths, is also observed at X-ray energies. The increase in hard X-ray emission could be the result of a tripling of the mass-loss rate in less than 4 months.
    Keywords: ASTRONOMY
    Type: Astrophysical Journal, Part 2 - Letters (ISSN 0004-637X); 445; 2; p. L21-L24
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  • 40
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    RX J0045.4+4154: A recurrent supersoft x-ray transient in M31 (1995)
    In:  Other Sources
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    Publication Date: 2011-08-24
    Description: Using data extracted from the ROSAT archive we have discovered a recurrent supersoft X-ray transient RX J0045.4+4154 in M31. The first outburst began on 1992 February 2 and continued for at least 4 days, until the end of the observation sequence. A second outburst that lasted more than 6 days was seen to begin on 1993 January 7. The X-ray spectrum on both occasions yields a characteristic blackbody temperature of approximately 90 eV. For a range of plausible continuum models, the hydrogen column density is (0.8-1.5) x 10(exp 21)/sq cm and is consistent with the source being located in M31. This implies an unabsorbed 0.1-2.0 keV peak luminosity of approximately 10(exp 38) ergs/sec. This is the first recurrent X-ray transient to be found in M31 and is particularly notable because it is much softer than the bright X-ray transients seen in our Galaxy. The spectrum is characteristic of the supersoft class of X-ray sources, which are thought to be accreting white dwarfs that have a hydrogen-burning surface layer. A fit to a white dwarf model atmosphere gives a temperature of 10(exp 6)K, the hottest found so far. This high temperature is consistent with a white dwarf mass of 1.3-1.4 solar mass, approaching the Chandrasekhar limit, and burning close to the nuclear stability limit.
    Keywords: ASTRONOMY
    Type: Astrophysical Journal, Part 2 - Letters (ISSN 0004-637X); 445; 2; p. L25-L28
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  • 41
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    America's foremost early astronomer (1995)
    In:  Other Sources
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    Publication Date: 2011-08-24
    Description: The life of 18th century astronomer, craftsman, and partriot David Rittenhouse is detailed. As a craftsman, he distinguished himself as one of the foremost builders of clocks. He also built magnetic compasses and surveying instruments. The finest examples of his craftsmanship are considered two orreries, mechanical solar systems. In terms of astronomical observations, his best-known contribution was his observation of the transit of Venus in 1769. Rittenhouse constructed the first diffraction grating. Working as Treasurer of Pennsylvania throughout the Revolution, he became the first director of the Mint in 1792. Astronomical observations in later life included charting the position of Uranus after its discovery.
    Keywords: ASTRONOMY
    Type: Sky & Telescope (ISSN 0037-6604); 89; 5; p. 38-41
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  • 42
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    Mg II h and k profiles in high-liminosity, late-type stars (1995)
    In:  Other Sources
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    Publication Date: 2011-08-24
    Description: Using high-resolution spectroscopic data taken with the Goddard High Resolution Spectrographic (GHRS) aboard the Hubble Space Telescope (HST) and with the International Ultraviolet Expolorer (IUE) satellite, we compare the profiles of the Mg II h and k lines seen in stars with spectral types ranging from early K through mid-M and luminosities from giants to supergiants. For all of these stars the lines are broad emission features with a central absorption. When plotted on a velocity scale the absorption features of the h and k lines agree very well in both shape and position, as do the blue wings of the emission component. The red wings of the emission, however, show a pronounced difference, with the k line wing consistently shifted to the red of the h line wing. At present the reason for this discrepancy is unknown, but we suggest several possibilities, including radiative transfer effects and high-speed stellar winds.
    Keywords: ASTRONOMY
    Type: The Astrophysical Journal, Part 1 (ISSN 0004-637X); 442; 1; p. 328-336
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  • 43
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    Results from ASCA (1995)
    In:  Other Sources
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    Publication Date: 2011-08-24
    Description: The X-ray observatory Advanced Satellite for Cosmology and Astrophysics (ASCA) (Astro-D) was launched in Feb 1993 and is now providing excellent spectro-imaging observations of objects from virtually every astronomical class. This paper reviews the scientific capabilities of ASCA using some of the first results from X-ray binaries, cataclysmic variables, and stars.
    Keywords: ASTRONOMY
    Type: Advances in Space Research (ISSN 0273-1177); 16; 3; p. 29-39
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  • 44
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    Infrared observations of an outburst of small dust grains from the nucleus of Comet P/Halley 1986 III at perihelion (1995)
    In:  Other Sources
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    Publication Date: 2011-08-24
    Description: A close examination of the 0.7- to 23-micron infrared data base acquired by Gehrz and Ney (1992), suggests that the nucleus of Comet P/Halley 1986 III emitted a burst of small dust grains during a 3-day period commencing within hours of perihelion passage on 1986 February 9.46 UT. The outburst was characterized by significant increases in the coma's grain color temperature T(sub obs), temperature excess (superheat: S = T(sub obs)/T(sub BB)), infrared luminosity, albedo, and 10-micron silicate emission feature strength. These changes are all consistent with the sudden ejection from the nucleus of a cloud of grains with radii of approximately 0.5 micron. This outburst may have produced the dust that was responsible for some of the tail streamers photographed on 1986 February 22 UT. The peak of the dust outburst occurred about 3 days before a pronounced increase in the water production rate measured by the Pioneer Venus Orbiter Ultraviolet Spectrometer. We suggest that jets that release large quantities of small particles may be largely responsible for some of the variable infrared behavior that has been reported for P/Halley and other comets during the past two decades. Such jets may also account for some of the differences IR Type I and IR Type II comets.
    Keywords: ASTRONOMY
    Type: Icarus (ISSN 0019-1035); 113; 1; p. 129-133
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  • 45
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    Global stratigraphy of Venus: Analysis of a random sample of thirty-six test areas (1995)
    In:  Other Sources
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    Publication Date: 2011-08-24
    Description: The age relations between 36 impact craters with dark paraboloids and other geologic units and structures at these localities have been studied through photogeologic analysis of Magellan SAR images of the surface of Venus. Geologic settings in all 36 sites, about 1000 x 1000 km each, could be characterized using only 10 different terrain units and six types of structures. Mapping of such units and structures in 36 randomly distributed large regions shows evidence for a distinctive regional and global stratigraphic and geologic sequence. On the basis of this sequence we have developed a model that illustrates several major themes in the history of Venus. Most of the history of Venus (that of its first 80% or so) is not preserved in the surface geomorphological record. The major deformation associated with tessera formation in the period sometime between 0.5-1.0 b.y. ago (Ivanov and Basilevsky, 1993) is the earliest event detected. Our stratigraphic analyses suggest that following tessera formation, extensive volcanic flooding resurfaced at least 85% of the planet in the form of the presently-ridged and fractured plains. Several lines of evidence favor a high flux in the post-tessera period but we have no independent evidence for the absolute duration of ridged plains emplacement. During this time, the net state of stress in the lithosphere apparently changed from extensional to compressional, first in the form of extensive ridge belt development, followed by the formation of extensive wrinkle ridges on the flow units. Subsequently, there occurred local emplacement of smooth and lobate plains units which are presently essentially undeformed. The major events in the latest 10% of the presently preserved history of Venus are continued rifting and some associated volcanism, and the redistribution of eolian material largely derived from impact crater deposits. Detailed geologic mapping and stratigraphic synthesis are necessary to test this sequence and to address many of the outstanding problems raised by this analysis.
    Keywords: ASTRONOMY
    Type: Earth, Moon, and Planets (ISSN 0167-9295); 66; 3; p. 285-336
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  • 46
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    Recent chaqnges in the IUE spectrum of the very young planetary nebula He 3-1357 (=SAO 244567) (1995)
    In:  Other Sources
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    Publication Date: 2011-08-24
    Description: We obtained the first high-dispersion IUE spectrum, and an additional low-dispersion spectrum of the very young planetary nebula He 3-1357 and its central star SDAO 244567. In 1988, it showed a very strong C IV lambda-1549 P Cygni profile which diminished and has disappeared by 1994, but C IV absorptions are seen in a high-resolution spectrum. The electron density from the C III F(lambda 1907)/F(lambda 1909) emission ratio is log N(sub e) = 4.1/cc. The older IUE data were reprocessed, and emission-line fluxes vary greatly for the period 1988-1994. The high-dispersion data show a rich Fe V and Fe VI absorption spectrum.
    Keywords: ASTRONOMY
    Type: Astrophysical Journal, Part 1 (ISSN 0004-637X); 443; 1; p. 245-248
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  • 47
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    Radio properties of narrow-lined Seyfert 1 galaxies (1995)
    In:  Other Sources
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    Publication Date: 2011-08-24
    Description: We have observed seven narrow-linedd Seyfert 1 (NLS1) galaxies and one high-ionization Seyfert 2 galaxy with the Very Large Array (VLA). Combining these observations with published data, we summarize the radio properties of the NLS1 galaxies for which spectropolarimetry was reported by Goodrich. Fifteen of these 17 objects now have published radio observations of high sensitivity, and only nine of those have been detected. For a Hubble parameter of 75 km/s/Mpc, the 6 cm radio powers range from 10(exp 20) to 10(exp 23) W/Hz, within the range previously found for other types of Seyfert galaxy. The median radio size of the nine VLA-detected galaxies is no larger than 300 pc, similar to the median size found by Ulvestad & Wilson for a distance-limited sample of Seyfert galaxies. Of the six NLS1 galaxies known to have significant intrinsic optical polarization, three have measurable radio axes. Two of those three galaxies have radio major axes close to 90 deg from their polarization position angles, while the third has an inner radio axis that may be nearly parallel to the polarization position angle. The former relationship is expected for a Seyfert 1 in a unified model of Seyfert galaxies, assuming no intrinsic continuum polarization.
    Keywords: ASTRONOMY
    Type: The Astronomical Journal (ISSN 0004-6256); 109; 1669; p. 81-86
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  • 48
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    The magnetic field in LYNDS 1457: Multiband photopolarimetry (1995)
    In:  Other Sources
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    Publication Date: 2011-08-24
    Description: We have performed multiband photopolarimetry toward stars behind the molecular cloud L1457 (MBM 12). This cloud is the nearest known molecular cloud (65 pc) and thought to be contained within the local 'hot bubble.' The polarization shows a regular structure, indicating that the cloud is threaded by an ordered magnetic field. The wavelength dependence of the polarization seems to indicate that the grains in L1457 have higher indices of refraction than normal for interstellar clouds. However, the wavelength of maximum polarization indicates that their size distribution is close to normal.
    Keywords: ASTRONOMY
    Type: Astrophysical Journal, Part 2 - Letters (ISSN 0004-637X); 443; 1; p. L49-L52
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  • 49
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    Topography of closed depressions, scarps, and grabens in the north Tharsis region of Mars: Implications for shallow crustal discontinuities and Graben formation (1995)
    In:  Other Sources
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    Publication Date: 2011-08-24
    Description: Using Viking Orbiter images, detailed photoclinometric profiles were obtained across 10 irregular depressions, 32 fretted fractures, 40 troughs and pits, 124 solitary scarps, and 370 simple grabens in the north Tharsis region of Mars. These data allow inferences to be made on the shallow crustal structure of this region. The frequency modes of measured scarp heights correspond with previous general thickness estimates of the heavily cratered and rigded plains units. The depths of the flat-floored irregular depressions (55-175 m), fretted fractures (85-890 m), and troughs and pits (60-1620 m) are also similar to scarp heights (thicknesses) of the geologic units in which these depressions occur, which suggests that the depths of these flat-floored features were controlled by erosional base levels created by lithologic contacts. Although the features have a similar age, both their depths and their observed local structural control increase in the order listed above, which suggests that the more advanced stages of associated fracturing facilitated the development of these depressions by increasing permeability. If a ground-ice zone is a factor in development of these features, as has been suggested, our observation that the depths of these features decrease with increasing latitude suggests that either the thickness of the ground-ice zone does not increase poleward or the depths of the depressions were controlled by the top of the ground-ice zone whose depth may decrease with latitude.
    Keywords: ASTRONOMY
    Type: Icarus (ISSN 0019-1035); 114; 2; p. 403-422
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  • 50
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    Evidence for chemical processing of precometary icy grains in circumstellar environments of pre-main-sequence stars (1995)
    In:  Other Sources
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    Publication Date: 2011-08-24
    Description: We report the detection of a broad absorption feature near 2166/cm in the spectrum of the Taurus cloud cource Elias 18. This pre-main-sequence source is the second in Taurus, the third in our survey, and the fifth known in the sky to show the broad 2166/cm absorption feature. Of equal importance, this feature is not seen toward several other embedded sources in our survey, nor is it seen toward the source Elias 16, located behind the Taurus cloud. Laboratory experiments with interstellar ice analogs show that such a feature is associated with a complex C triple bonded to N containing compound (called X(C triple bonded to N)) that results from high-energy processing (ultraviolet irradiation or ion bombardment) of simple ice components into more complex, organic components. We find a nonlinear anticorrelation between the abundance of X(C triple bonded to N) and frozen CO components in nonpolar lattices. We find no correlation between the abundance of X(C triple bonded to N) and frozen CO in polar lattices. Because the abundances of frozen CO and H2O are strongly correlated with each other and with visual extinction toward sources embedded in and located behind the Taurus molecular cloud, these ice components usually are associated with intracloud material. Our results indicate that X(C triple bonded to N) molecules result from chemical processing of dust grains dominated by nonpolar icy mantles in the local environments of pre-main-sequence stars. Such processing of icy grains in the early solar system may be an important source of organic compounds observed in minor solar system bodies. The delivery of these organic compounds to the surface of the primitive Earth through comet impacts may have provided the raw materials for prebiotic chemistry.
    Keywords: ASTRONOMY
    Type: Astrophysical Journal, Part 1 (ISSN 0004-637X); 439; 1; p. 279-287
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    N IV emission lines in the ultraviolet spectra of gaseous nebulae (1995)
    In:  Other Sources
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    Publication Date: 2011-08-24
    Description: Theoretical electron density sensitive emission-line ratios, determined using electron impact excitation rates calculated with the R-matrix code, are presented for R = I(2s(sup 2) (1)S-2s2p 3P(sub 2))/I(2s(sup 2) (1)S-2s2p 3P(sub 1) = 1(1483 A)/I(1486 A) in N IV. These are found to be up to an order of magnitude different from those deduced by previous authors, principally due to the inclusion of excitation rates for transitions among the 2s2p (3)p fine-structure levels. The observed values of R for several planetary nebulae, symbiotic stars and the Cygnus Loop supernova remnant, measured from spectra obtained with the International Ultraviolet Explorer (IUE) satellite and the Hopkins Ultraviolet Explorer (HUT), lead to electron densities which are in excellent agreement with those deduced from line ratios in other species. This provides observational support for the accuracy of the atomic data adopted in the present calculations.
    Keywords: ASTRONOMY
    Type: Astrophysical Journal, Part 1 (ISSN 0004-637X); 438; 1; p. 500-503
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    The X-ray telescope on board ASCA (1995)
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    Publication Date: 2011-08-24
    Description: The Advanced Satellite for Cosmology and Astrophysics (ASCA) instrument uses identical conical foil X-ray mirrors for its four telescopes. One of the major advantages of ASCA's telescopes is the first time ever use of X-ray imaging over a broad energy band and high throughput for conducting astronomical spectroscopy. Nested thin foil reflectors make possible a large effective area up to 10 keV, even under the tight weight restriction of the ASCA spacecraft. The expected characteristics of the ASCA mirrors are summarized based on ray tracings and pre-flight calibrations. The total effective area of four telescopes at 1 and 7 keV are approximately 1200 and 600 sq cm, respectively. The image size (half power diameter: HPD) is about 3 min. The field of view is 24 min and 16 min full width at half maximum for 1 and 7 keV, respectively. Observations of several X-ray sources from space during the performance verification phase have confirmed those performances as well as the alignment of the optical systems.
    Keywords: ASTRONOMY
    Type: PASJ: Publications of the Astronomical Society of Japan (ISSN 0004-6264); 47; 1; p. 105-114
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    Near- and far-infrared observations of interplanetary dust bands from the COBE diffuse infrared background experiment (1995)
    In:  Other Sources
    Details
    Publication Date: 2011-08-24
    Description: Data from the Diffuse Infrared Background Experiment (DIRBE) instrument aboard the Cosmic Background Explorer Satellite (COBE) spacecraft have been used to examine the near and far infrared signatures of the interplanetary dust (IPD) bands. Images of the dust band pairs at ecliptic latitudes of +/- 1.4 deg and +/- 10 deg have been produced at DIRBE wavelengths from 1.25 to 100 micrometers. The observations at the shorter wavelengths provide the first evidence of scattered sunlight from particles responsible for the dust bands. It is found that the grains in the bands and those in the smooth IPD cloud have similar spectral energy distributions, suggesting similar compositions and possibly a common origin. The scattering albedos from 1.25 to 3.5 micrometers for the grains in the dust bands and those in the IPD cloud are 0.22 and 0.29, respectively. The 10 deg band pair is cooler (185 +/- 10 K) than the smooth interplanetary dust cloud (259 +/- 10 K). From both parallactic and thermal analyses, the implied location of the grains responsible for the peak brightness of the 10 deg band pair is 2.1 +/- 0.1 AU the Sun A parallactic distance of 1.4 +/- 0.2 AU is found for the peak of the 1.4 deg band pair.
    Keywords: ASTRONOMY
    Type: Astrophysical Journal (ISSN 0004-637X); 442; 2, Pa; p. 662-667
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    Elliptically polarized bursty radio emissions from Jupiter (1995)
    In:  Other Sources
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    Publication Date: 2011-08-24
    Description: We report a new component of Jovian radio emission observed by the Ulysses spacecraft when Ulysses was at high Jovigraphic latitudes (greater than or approximately = 30 deg north or south of the Jovian magnetic equator). This bursty high-latitude emission is elliptically polarized in the right-hand sense when observed from northern latitudes and in the left-hand sense when observed from southern latitudes, consistent with extraordinary mode. The orientation of the polarization ellipse is observed to systematically vary with time relative to the observer. It is argued that the elliptically-polarized nature of the emission is intrinsic to the source region.
    Keywords: ASTRONOMY
    Type: Geophysical Research Letters (ISSN 0094-8276); 22; 4; p. 345-348
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    EGRET observations of gamma-ray emission from the interstellar gas in Orion (1995)
    In:  Other Sources
    Details
    Publication Date: 2011-08-24
    Description: The high-energy diffuse gamma-ray emission from the interstellar gas in Orion was studied using observations from the Energetic Gamma-Ray Experiment Telescope (EGRET) on the Compton Gamma-Ray Observatory (CGRO) and radio surveys of the H I and CO emission. The good correlation of the gamma-ray emission with the atomic and molecular gas permits determination of the gamma-ray emissivity per nucleon in the interstellar medium and the molecular mass calibrating ratio N(H2)/W(sub co) in Orion. The integral gamma-ray emissivity is (1.7 +/- 0.1) x 10(exp -26)/s/sr for E greater than 100 MeV, in good agreement with expectations from studies of the diffuse emission on larger scales. The N(H2)/W(sub co) ratio is (1.06 +/- 0.14) x 10(exp 20)/sq cm/(K km/s), approximately 40% less than the commonly adopted Galactic average. We find no evidence for variations of the cosmic-ray density or N(H2)/W(sub co) ratio in Orion at the sensitivity and resolution of EGRET.
    Keywords: ASTRONOMY
    Type: Astrophysical Journal, Part 1 (ISSN 0004-637X); 441; 1; p. 270-280
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    The megaparsec-scale environments of BL Lacertae objects (1995)
    In:  Other Sources
    Details
    Publication Date: 2011-08-24
    Description: We compare observations of BL Lac megaparsec-scale clustering environments with those for F-R I radio galaxies V and R image data are used to show that the strengths of the clustering measured via spatial cross-correlation amplitude are similar for the two types of galaxies and are consistent with Abel richness class 0. We discuss the implications this has for the origin of the BL Lac phenomena. We also examine the evolution of clustering environments of F-R I radio galaxies and BL Lac objects with redshift.
    Keywords: ASTRONOMY
    Type: Astrophysical Journal, Part 1 (ISSN 0004-637X); 441; 1; p. 113-119
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    Moderate-resolution spectral standards from lambda 5600 to lambda 9000 (1995)
    In:  Other Sources
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    Publication Date: 2011-08-24
    Description: We present a grid of stellar classification spectra of moderate resolution (R approximately 1500) in the range lambda lambda 5600-9000 A, compiled from high signal-to noise spectra of 275 stars, most in the open clusters Praesepe and M67. The grid covers dwarfs from types B8 through M5, giants from G8 through M7, and subgiants from F5 through K0. We catalog atomic and molecular absorption features useful for stellar classification, and demonstrate the use of luminosity-sensitive features to distinguish between late-type dwarf and giant stars. The entire database is made available in digital format on anonymous ftp and through the World Wide Web.
    Keywords: ASTRONOMY
    Type: Astronomical Journal (ISSN 0004-6256); 109; 3; p. 1379-1390
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    Meteor stream activity. 2: Meteor outbursts (1995)
    In:  Other Sources
    Details
    Publication Date: 2011-08-24
    Description: In the past two centuries, alert amateur and professional meteor astronomers have documented 35 outbursts of 17 individual meteor streams well enough to allow the construction of a homogeneous set of activity curves. These curves add to similar profiles of the annual streams in a previous paper (Paper 1). This paper attempts to define the type and range of phenomena that classify as meteor outbursts from which the following is concluded: Outbursts are associated with the return of the comet to perihelion (near-comet type outbursts), but occur also when the parent comet is far from perihelion and far from the Earth (far-comet type). All outbursts of a given type only, depending on encounter geometry. The activity curves, expressed in terms of Zenith Hourly Rates (ZHR), have a shape that is generally well described by: ZHR = ZHR(sub max) 10(sup(-B (the absolute value of lambda (sub dot in a circle) - lambda (sup max) (sub dot in a circle))). The steepness of the slopes varies from an exponent of B = 7 to B = 220 per degree of solar longitude, with a typical value of B = 30. In addition, most near-comet type outbursts have a broader component underlying the main peak with B approximately 1 - 7.The duration Delta t is approximately 1/B of the main peak is almost independent of location near the comet, while the background component varies considerably in duration and relative intensity from one return to another. The two components in the activity curve are due to two distinct structures in the dust distribution near the parent comet, where the main component can be due to a sheet of dust that emanates from the IRAS dust trail. This brings the total number of distinct structures in meteor streams to four, including the two structures from the annual stream activity in Paper 1.
    Keywords: ASTRONOMY
    Type: Astronomy and Astrophysics (ISSN 0004-6361); 295; 1; p. 206-235
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    Intense radio outburst from the supermassive star Eta Carinae (1995)
    In:  Other Sources
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    Publication Date: 2011-08-24
    Description: On five occasions between 1992 June 29 and 1994 May 3, we have used the Australia Telescope Compact Array (ATCA) to image Eta Carinae at a wavelength of 3 cm and a resolution of 1 arcsec. These observations have revealed remarkable activity. Since 1992 June, the total flux density has increase from 0.8 to 2.2 Jy, and the original single compact source has grown to a complex of sources spread over an area of about 16 sq arcsec. Strong hydrogen recombination-line spectral emission has appeared at the site of the strongest of these new sources. This recombination emission has the largest spectral width ever observed from a star, +/- 250 km/s, and reveals gas with turbulent velocities as great as 250 km/s approaching us at an average velocity of about 200 km/s. We believe that this radio outburst has been caused by a more than threefold increase of ultraviolet luminosity, and consequent ionization of previously neutral gas clouds.
    Keywords: ASTRONOMY
    Type: Astrophysical Journal, Part 2 - Letters (ISSN 0004-637X); 441; 2; p. L73-L76
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    Multifrequency observations of KAZ 102 during the ROSAT all-sky survey (1995)
    In:  Other Sources
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    Publication Date: 2011-08-24
    Description: The bright quasar Kaz 102, which lies in the vicinity of the North Ecliptic Pole, was monitored during the ROSAT All Sky Survey for 121.5 days from 1990 July 30 to 1991 January 25. In the course of the survey, optical photometry with various filters was peformed at several epochs, together with UV (IUE) and optical spectrophotometry. The spectral energy distribution in the 3 x 10(exp 14) -3 x 10(exp 17) Hz range is obtained simultaneously among the various frequencies to less than or = 1 day. No clear case of variability can be made in the X-rays, while in the optical and UV variability of 10%-20% is apparent. An analysis of IUE and Einstein archives indicates a doubling timescale of years for the UV and soft X-ray flux. The X-ray photon index, which in 1979 was rather flat (Gamma = 0.8(+0.6 -0.4), in 1990/1991 was found to be Gamma = 2.22 +/- 0.13, a typical value for radio-quiet quasars in this energy range. The overall energy distribution and the variability are discussed.
    Keywords: ASTRONOMY
    Type: Astrophysical Journal (ISSN 0004-637X); 442; 2, Pa; p. 589-596
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    Calibrating the broad band X-ray telescope (1995)
    In:  Other Sources
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    Publication Date: 2011-08-24
    Description: This paper describes the calibration of the two solid-state Si(Li) X-ray detectors and the X-ray telescopes that flew as part of Goddard Space Flight Center's Broad Band X-Ray Telescope (BBXRT) experiment on board the space shuttle Columbia in 1990 December. During the 9 day shuttle mission, BBXRT performed approximately 150 observations of 82 celestial sources. The content of the archive is summarized here. Although BBXRT had a relatively short life, it stands as a milestone in X-ray astronomy as being the first instrument to offer moderate spectral resolution over a wide bandpass (0.3-12.0 keV). Among other things, this paper discusses the effective area calibration of the instrument, the flux calibration and flux corrections for off-axis observations, the detector background, and optimal background subtraction techniques. The on-axis effective area calibration for the central detector elements was performed using data from the Crab Nebula, while other carefully selected targets were used for calibration of the outer detector elements. The remaining systematic uncertainties in the effective area calibration for point sources observed both on and off axis are generally less than 5%-10%. The energy scale is known to better than 0.5% at 6.0 keV for both detectors. The results presented here have an impact on the calibration of other medium resolution X-ray experiments such as the CCDs on board ASCA (Astro-D) as well as the Advanced X-Ray Astrophysics Facility detectors.
    Keywords: ASTRONOMY
    Type: Astrophysical Journal Supplement Series (ISSN 0067-0049); 96; 1; p. 303-324
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    The High Resolution Spectrograph for the Space Telescope (1982)
    In:  CASI
    Details
    Publication Date: 2009-11-16
    Description: The High Resoltuion Spectrograph (HRS) in conjunction with the Space Telescope (ST), extends ultraviolet astronomical spectroscopy to higher spectra, spatial, and time resolutions than previously achieved, as well as to fainter and more distant celestial objects. Other significant advances inherent in the instrument are high photometric accuracy and efficient operation via exposure meter control and real time rejection of bad data. These capabilities are provided to accomplish the scientific programs of the HRS investigation definition team, which concern the interstellar medium, stellar winds, and evolutionary aspects of stellar atmosphere studies; the determination of chemical abundances relevant to stellar evolution; the investigation of quasars and Seyfert galaxy nuclei; and the analysis of the atmospheres of solar system objects, including comets.
    Keywords: ASTRONOMY
    Type: Space Telescope Science Inst. The Space Telescope Obs.; p 76-105
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    The PDS-VAX intelligent plate scanning system of Trieste Astronomical Observatory (1984)
    In:  CASI
    Details
    Publication Date: 2006-02-14
    Description: An intelligent subsystem for interfacing a PDS1010A digital microdensitometer to a DEC DR11W DMA 16 bit UNIBUS port in DEC VAX VMS environment was tested. The subsystem employs two MOTOROLA M68000 microprocessors with 128 KB data memory. The PDS primitives and the user defined high level scanning functions and preprocessing modules are loaded from the host computer into two 8 KB RAM memories in the microprocessors using a dedicated PDS control language. The subsystem is planned to employ a nonstandard photomultiplier electronics. Two design schemes were tested: (1) based on three amplifiers of gain 10 cascaded and multiplexed to a 12 bit AD converter, and (2) based on a single amplifier of gain 100 and two 14 bit AD converters.
    Keywords: ASTRONOMY
    Type: NASA. Goddard Space Flight Center Astron. Microdensitometry Conf.; p 175-187
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    Reflections on the Space Telescope (1982)
    In:  CASI
    Details
    Publication Date: 2006-02-14
    Description: The significance of the Space Telescope for the advancement of astronomy and astrophysics is described. The current state of knowledge in astronomy and cosmology is summarized and unanswered questions in those fields discussed. The rapid evolution of modern astronomy and the need for systematic observations are stressed.
    Keywords: ASTRONOMY
    Type: Space Telescope Science Inst. The Space Telescope Obs.; p 121-134
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    Astrometric observations with the Space Telescope (1982)
    In:  CASI
    Details
    Publication Date: 2006-02-14
    Description: Astrometry with the Space Telescope (ST) is performed using one of the fine guidance sensors (FGS). The FGS, which is based on a pair of Koester's prism interferometers, one for each axis, is capable of measuring the position of one object relative to another with an accuracy of 0.002 arcseconds. Astrometric Data Reduction Software (ADRS) available to the astrometric user of ST is described. The kinds of problems the space telescope astrometry team plans to investigate using ST are discussed.
    Keywords: ASTRONOMY
    Type: Space Telescope Science Inst. The Space Telescope Obs.; p 114-120
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    The wide field/planetary camera (1982)
    In:  CASI
    Details
    Publication Date: 2006-02-14
    Description: A wide site of potential astronomical and solar system scientific studies using the wide field planetary camera on space telescope are described. The expected performance of the camera as it approaches final assembly and testing is also detailed.
    Keywords: ASTRONOMY
    Type: Space Telescope Science Inst. The Space Telescope Obs.; p 28-39
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    European astronomy and the Space Telescope: The Space Telescope European Coordinating Facility (1982)
    In:  CASI
    Details
    Publication Date: 2006-02-14
    Description: The role of the European Coordinating Facility is described. European participation in the Space Telescope Science Institute and the relation of Space Telescope to ground-based astronomy in Europe are discussed.
    Keywords: ASTRONOMY
    Type: Space Telescope Science Inst. The Space Telescope Obs.; p 16-19
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  • 68
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    Spectroscopy in X-ray astronomy (1981)
    In:  CASI
    Details
    Publication Date: 2006-06-04
    Description: Detailed features in cosmic X-ray sources and their associated temporal variation over a wide energy range were studied. Excess emission and absorption at approximately 6 to 7 kiloelectron volts in the spectra of supernova remnants, binary X-ray sources, and clusters of galaxies were observed. A gas scintillation proportional counter (GSPC) will be used as the detector system. In the gas scintillator the principal limitation is due to the statistics of the initial ionization process only.
    Keywords: ASTRONOMY
    Type: NASA. Marshall Space Flight Center Spacelab Mission 1 Expt. Descriptions; 3 p
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    Far ultraviolet astronomy using the FAUST telescope (1981)
    In:  CASI
    Details
    Publication Date: 2006-06-04
    Description: The Far Ultraviolet Space Telescope (FAUST) a compact, wide field-of-view, far ultraviolet instrument designed for astronomical observations of extended and point sources is discussed. The design and application of the instrument are described. The prime objective is to observe faint astronomical sources with sensitivities higher than previously available. Scientific programs will include: (1) a search for ultraviolet stars which are predicted to exist at the stage of evolution prior to the final death of a star; (2) observations of galaxies and quasars; and (3) joint programs with other Spacelab 1 experiments. The secondary objective is to verify the suitability of the Spacelab as a platform for far ultraviolet astronomy: data will be provided on the ultraviolet background levels due to astronomical, terrestrial, and spacecraft generated sources; the levels of contaminants which affect ultraviolet instruments; and the capability of the Orbiter for stable pointing at celestial sources for useful periods of time.
    Keywords: ASTRONOMY
    Type: NASA. Marshall Space Flight Center Spacelab Mission 1 Expt. Descriptions; 3 p
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    The High Speed Photometer for the Space Telescope (1982)
    In:  CASI
    Details
    Publication Date: 2006-02-14
    Description: An overview of the high speed photometer (HSP), its optics and detectors, its electronics, its mechanical structure, and some observational considerations are presented. The capabilities and limitations of the HSP are outlined.
    Keywords: ASTRONOMY
    Type: Space Telescope Science Inst. The Space Telescope Obs.; p 106-113
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    The Faint Object Camera (1982)
    In:  CASI
    Details
    Publication Date: 2006-02-14
    Description: The Faint Object Camera fully exploits the spatial resolution capability of the Space Telescope on the very faintest detectable objects over a broad wavelength range. A full complement of filters, objective prisms and polarizers, a choice of coronograhic masks, and a variety of scan formats extend the scientific versatility of the direct imaging mode. In addition, the Faint Object Camera provides the unique facility of long-slit spectroscopy to Space Telescope observers.
    Keywords: ASTRONOMY
    Type: Space Telescope Science Inst. The Space Telescope Obs.; p 40-54
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    Astronomical capabilities of the Faint Object Spectrograph on Space Telescope (1982)
    In:  CASI
    Details
    Publication Date: 2006-02-14
    Description: Examples of scientific observing programs planned with the Faint Object Spectrograph on Space Telescope are presented. An overview of the spectrograph design and operation is presented. The expected astronomical performance of the instrument is described in some detail.
    Keywords: ASTRONOMY
    Type: Space Telescope Science Inst. The Space Telescope Obs.; p 55-75
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    The Space Telescope Observatory (1982)
    In:  CASI
    Details
    Publication Date: 2006-02-14
    Description: The history of the observatory is briefly described, as is the overall system design. The principal design features that are important to the scientific user are described. The present status of preparation for launch in the spring of 1985 is summarized.
    Keywords: ASTRONOMY
    Type: Space Telescope Science Inst. The Space Telescope Obs.; p 20-27
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    STEP flight experiments Large Deployable Reflector (LDR) telescope (1984)
    In:  CASI
    Details
    Publication Date: 2006-04-03
    Description: Flight testing plans for a large deployable infrared reflector telescope to be tested on a space platform are discussed. Subsystem parts, subassemblies, and whole assemblies are discussed. Assurance of operational deployability, rigidization, alignment, and serviceability will be sought.
    Keywords: ASTRONOMY
    Type: NASA. Langley Research Center STEP Expt. Requirements; p 257-278
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    Science operations with Space Telescope (1982)
    In:  CASI
    Details
    Publication Date: 2006-02-14
    Description: The operation, instrumentation, and expected contributions of the Space Telescope are discussed. Space Telescope capabilities are described. The organization and nature of the Space Telescope Science Institute are outlined, including the allocation of observing time and the data rights and data access policies of the institute.
    Keywords: ASTRONOMY
    Type: The Space Telescope Obs.; p 1-15
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    Simultaneous UV, optical and radio monitoring of the BL Lac object OJ 287 in March 1993 (1995)
    In:  Other Sources
    Details
    Publication Date: 2011-08-24
    Description: The BL Lacertae object OJ 287 was intensively monitored with the IUE satellite from 1993 March 15 to 20 in the 2000-3000 A wavelength region. The very low emission state of the source hampered the detection during part of the 23 performed exposures. The light curve at 2650 A constructed with the 11 best images exhibits a variable trend with a factor is less than or approximately 2 enhancement of the flux in about 3 hours. Simultaneous ground based observations show an optical flux variability of smaller amplitude, but correlated with the UV light curve without any apparent lag. The radio light curve is nearly constant. The UV emission state is the weakest observed in 15 years for this flaring blazard, being a factor of less than orapproximately 20 lower than the maximum recorded one.
    Keywords: ASTRONOMY
    Type: Advances in Space Research (ISSN 0273-1177); 16; 3; p. 57-60
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    What's new, Voyager: The discoveries continue (1995)
    In:  Other Sources
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    Publication Date: 2011-08-24
    Description: The twin Voyager spacecraft, launched nearly two decades ago, continue to operate and are now searching for the edge of our solar system, the heliopause. Voyager's giant-planet flybys of Jupiter, Saturn, Uranus, and Neptune have provided data that are likely to remain the definitive data set for the foreseeable future and have led to many ongoing discoveries. As the spacecraft move toward the heliopause, they are also providing data on the structure of the heliosphere. This article discusses the discoveries resulting from the flyby and heliosphere data that have been made within the past five years.
    Keywords: ASTRONOMY
    Type: Planetary Report (ISSN 0736-3680); 15; 4; p. 4-9
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    The abundances of Pt, Au, and Hg in the chemically peculiar HgMn-type stars kappa Cancri and chi Lupi (1995)
    In:  Other Sources
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    Publication Date: 2011-08-24
    Description: Echelle mode spectra obtained with the Goddard High Resolution Spectrograph (GHRS) onboard the Hubble Space Telescope (HST) have been used to determine the abundances of the heavy elements Pt, Au, and Hg in the chemically peculiar HgMn-type stars kappa Cancri and chi Lupi. The abundances were determined by fitting observed line profiles with synthetically generated spectra and are found to be enhanced relative to solar system values by between three and five orders of magnitude in both stars. The Hg isotope mixture in kappa Cancri is found to resemble the terrestrial mixture while that of chi Lupi is dominated by the heaviest isotope. As determined from multiple ionization states, the abundances place constraints upon theories attempting to explain the large superficial abundances of heavy elements.
    Keywords: ASTRONOMY
    Type: Astrophysical Journal, Part 1 (ISSN 0004-637X); 444; 1; p. 438-451
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    GHRS observations of cool, low-gravity star. 2: Flow and turbulent velocities in the outer atmosphere of gamma CRU CIS (M3.4 III) (1995)
    In:  Other Sources
    Details
    Publication Date: 2011-08-24
    Description: The Goddard High Resoulution Spectrograph (GHRS) on the Hubble Space Telescope (HST) has been used to obtain medium (R = 20,000) and high (R = 85,000) resoultion UV spectra of chromosphere emission features for the M3.4 III star gamma Cru. Small Science Aperture (SSA) G270M and Echelle-B spectra of selected regions in the 2300-2850 A range were obtained to determine the kinematics of the chromosphere using lines of C2), Fe2, Co2, Si1/2), Ni2, Mn2, and Mg2. Profiles of C2) (UV 0.01) lines and fluorescently excited lines of low optical depth indicate average turbulent velocities (Doppler FWHM) of 30.2 +/- 1.3 and 28.8 +/- 1.3 km/s, respectively. The fluorescent emission lines (mean RV = 21.3 +/- 0.9 km/s) and the wings of the emission components of Fe2 lines (mean RV = 22.8 +/- 0.4 km/s) are approximately at rest relative to the radial velocity of the star (21 km/s), while the C2) lines show a modest inflow (mean RV = 23.1 +/- 0.9 km/s). The more opaque lines of Fe2 and Mg2 exhibit complex profiles resulting from line formation in an optically thick, extended expanding atmosphere. The emission wings of these lines are broadened by multiple scattering, and they are centered near the photospheric radial velocity. Closer to line center, these strong lines show a strong blueshifted self-absorption feature (already seen in IUE data), indicative of formation in an expanding chromosphere, and a previously unseen dip in the profiles on the red side of line center. The absorption components, when extracted using simple Gaussian fits, show strong correlations with the relative optical depths of the lines. The derived absorption flow velocities converge to the photospheric velocity as one examines spectra features formed deeper in the atmosphere. The blueward abosrption velocity increases in magnitude from about 7 to 14 km/s with increasing line optical depth - the strong absorptions directly map the acceleration of the outflowing stellar wind, while the interpretation of the weaker redshifted abosrptions is more ambiguous, indicating either an inflow of material or formation in an extended, spherically expanding outflow. The Mg2 and Fe2 profiles, taken together, imply that the wind speed decreases between the atmospheric layers where the Mg2 and Fe2 self-absorption components are formed. Interstellar absorptions are seen in the resonance lines of Mg2 (UV 1) and Fe2 (UV1) with zero-volt lower levels, at about -3 km/s, consistent with models of the interstellar medium in the direction of gamma Cru. Finally, we have detected the Mg2 'satellite lines' seen in solar spectra obtained above the limb. In gamma Cru these lines are probably fluorescently excited by H Ly beta.
    Keywords: ASTRONOMY
    Type: Astrophysical Journal, Part 1 (ISSN 0004-637X); 444; 1; p. 424-437
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    The crash on Jupiter: Looking for answers in the impacts (1995)
    In:  Other Sources
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    Publication Date: 2011-08-24
    Description: Scientists are still trying to piece together what exactly occurred when comet fragments from Shoemaker-Levy 9 impacted with Jupiter last year. Several theories have been from the data received from Galileo and the Hubble Space Telescope (HST) together with the modeling of the impacts using supercomputers, scientists hope to discover the answers to their questions and perhaps to resolve the differences that have arisen between the different model simulations.
    Keywords: ASTRONOMY
    Type: Planetary Report (ISSN 0736-3680); 15; 2; p. 12-14
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  • 81
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    Millisecond pulsars: Timekeepers of the cosmos (1995)
    In:  Other Sources
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    Publication Date: 2011-08-24
    Description: A brief discussion on the characteristics of pulsars is given followed by a review of millisecond pulsar discoveries including the very first, PRS B1937+21, discovered in 1982. Methods of timing millisecond pulsars and the accuracy of millisecond pulsars as clocks are discussed. Possible reasons for the pulse residuals, or differences between the observed and predicted pulse arrival times for millisecond pulsars, are given.
    Keywords: ASTRONOMY
    Type: Sky & Telescope (ISSN 0037-6604); 89; 4; p. 18-23
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  • 82
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    OSSE observations of 1E 1740.7-2942 in 1992 September (1995)
    In:  Other Sources
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    Publication Date: 2011-08-24
    Description: We present data on the galactic X-ray source 1E 1740.7-2942 from the Oriented Scintillation Spectrometer Experiment (OSSE) on board NASA's Compton Gamma Ray Observatory (CGRO). Episodes of increased low-energy gamma radiation have been reported from this source, including 1-day events in 1990 October and 1992 September. These events, of intensity 7 x 10(exp -3) and 4 x 10(exp -3) photons/sq cm/s, respectively, have been interpreted as broadened and redshifted positron annihilation radiation. OSSE conducted observations of the Galactic Center region during a 21-day interval from 1992 September 17 thru 1992 October 8. This includes the time of increased 200-450 keV emission from 1E 1740.7-2942 reported by SIGMA. The OSSE observations do not confirm this event. For the specific outburst recorded by SIGMA, 1992 Sep. 19.42-20.58 (UT), OSSE data provide an upper limit (3 sigma) of 2.4 x 10(exp -3) photons/sq cm/s.
    Keywords: ASTRONOMY
    Type: Astronomy and Astrophysics (ISSN 0004-6361); 295; 2; p. L23-L26
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  • 83
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    Abell 548: An X-ray and optical analysis of substructure (1995)
    In:  Other Sources
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    Publication Date: 2011-08-24
    Description: X-ray observations of Abell 548 reveal that the hot gas in this cluster is at least as complex as the galaxy distribution. Our ROSAT Position Sensitive Proportional Counter (PSPC) image is used in conjunction with optical data from the Minnesota plate-scanning project and redshift data in the literature to investigate the degree of substructure in the intracluster medium and the galaxy distribution. A548 has several X-ray components: hot gas associated with clumps of galaxies, individual sources, and a newly discovered diffuse component. This diffuse component may be promordial gas falling into the cluster for the first time. The optical data suggest that this cluster consists of four major components, not three (as indicated when velocity data are ignored). Simple models of the orbital dynamics suggest that the cluster may not yet have reached its turnaround radius.
    Keywords: ASTRONOMY
    Type: Astrophysical Journal, Part 1 (ISSN 0004-637X); 440; 1; p. 48-59
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  • 84
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    Infrared mapping of galaxian centers: Star forming regions with kiloparsec scale sizes (1984)
    In:  Other Sources
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    Publication Date: 2011-08-19
    Description: A 1 to 20 micron mapping of the centers of galaxies encompassing the regions that extend out to several kiloparsecs from the nuclei is reviewed. Power emerging at or = 5 microns is a direct measure of the number of young stars present. This conclusion is strongly supported by the large-scale association of the infrared-emitting regions with visual continuum and line emission indicative of young stars, and by the similarity of the energy distributions to those of Galactic HII region/molecular cloud complexes. Much of the young-star activity is completely hidden from view. At shorter wavelengths, a variety of processes, including bremsstrahlung, are evident.
    Keywords: ASTRONOMY
    Type: Royal Observatory Star Formation Workshop; p 183-198
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  • 85
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    The Gamma-Ray Observatory mission objectives and its significance for gamma-ray astronomy (1984)
    In:  Other Sources
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    Publication Date: 2011-08-18
    Description: The Gamma Ray Observatory (GRO) is an approved NASA mission, programmed for launch in 1988. Its complement of four detectors has established goals: (1) to study the nature of compact gamma-ray sources such as neutron stars and black holes, or objects whose nature is yet to be understood; (2) to search for evidence of nucleosynthesis especially in the regions of supernovae; (3) to study structural features and dynamical properties of the Galaxy; (4) to explore other galaxies, especially the extraordinary types such as radio, Seyferts, and quasars; and (5) to study cosmological effects by examining the diffuse radiation in detail. This paper discusses the design, objectives, and expected scientific results of each of the GRO instruments in view of the GRO mission goals.
    Keywords: ASTRONOMY
    Type: Advances in Space Research (ISSN 0273-1177); 3; 10-12
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  • 86
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    The S201 far-ultraviolet imaging survey. II - A field in Cygnus (1984)
    In:  Other Sources
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    Publication Date: 2011-08-18
    Description: Far-ultraviolet imagery of a region in Cygnus, a 20 deg diameter field centered near (1950) R. A. 21 h 31.2 m decl. +37 deg 25 arcmin, was obtained by the S201 far-ultraviolet camera during the Apollo 16 mission. In a 10 minute exposure covering the 1250-1600 A wavelength range (effective wavelength 1400 A), 730 star images can be detected, corresponding to a limiting ultraviolet magnitude of about m (1400) = 10. Assuming nominal interstellar extinction values in this region near the galactic plane, this result corresponds to the detection of A0 V stars to a distance of 300 pc and of B0 V stars to 1500 pc. Uncertainties in spectral classification and interstellar extinction for individual objects are probably more significant than calibration or measurement errors. Most of the objects detected are identified with stars in the Smithsonian Astrophysical Observatory Star Catalog (1966), or the Catalog of Stellar Identifications (1979) or both, but 87 objects remain unidentified (or are identified with late-type stars).
    Keywords: ASTRONOMY
    Type: Astrophysical Journal Supplement Series (ISSN 0067-0049); 54; 271-290
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  • 87
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    Determining asteroid masses from perturbations on Mars (1984)
    In:  Other Sources
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    Publication Date: 2011-08-18
    Description: The orbit of Mars is perturbed more than 5 m, a value compatible with the accuracy of the Viking Lander ranging data, by about three dozen asteroids. In addition to larger asteroids throughout the belt, significant perturbations of long period are generated by smaller objects near commensurabilities with Mars. The largest periodic terms induced by 1 Ceres and 2 Pallas have amplitudes of 0.8 and 0.2 km, respectively, both with 10-year periods. Due to a near commensurability, 4 Vesta causes a 5-km, 52-year term. While the Viking ranges will yield significant mass determinations for the largest three asteroids, and some of the smaller bodies should be detectable, it will be difficult to separate the smaller bodies with useful accuracies. Accurate discrimination must await range data from future missions to Mars or other bodies in the neighborhood of the asteroid belt. The Viking ranges can also yield improved masses for the outer planets (except Pluto), an application which is being exploited by groups analyzing these data. Uncertainties in the asteroid masses limit the ultimate accuracy of the Viking determinations of both the long time scale motion of the system of the inner four planets with respect to an inertial frame and the rate of change of the gravitational constant.
    Keywords: ASTRONOMY
    Type: Icarus (ISSN 0019-1035); 57; 1-13
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  • 88
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    A search for the 10-micron silicate feature in periodic Comet Grigg-Skjellerup (1984)
    In:  Other Sources
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    Publication Date: 2011-08-18
    Description: A 10-micron spectrum of periodic Comet Grigg-Skjellerup was obtained on 22 June 1982 with the UCL array spectrometer at the United Kingdom Infrared Telescope, Mauna Kea. No emission feature is obvious in the spectrum. The observed spectrum can be fit equally well by a model of small hot absorbing grains or by a composite model with less than or equal to 30 percent (3sigma) warm, 'dirty' silicate grains. The latter model is consistent with the silicate abundance in Comet Kohoutek, which did display an emission feature at 10 microns.
    Keywords: ASTRONOMY
    Type: Astronomical Journal (ISSN 0004-6256); 89; 170
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  • 89
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    Broad band X-ray astronomical spectroscopy (1984)
    In:  Other Sources
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    Publication Date: 2011-08-18
    Description: The Broad Band X-Ray Telescope (BBXRT) experiment has been designed for high sensitivity, moderate resolution spectrophotometry of cosmic sources in the range 0.5 to 12 keV. Principal elements are two co-aligned imaging telescopes with cooled Si(Li) detectors at each focus. The mirror design uses an approximate geometry of tightly nested, conical, foil reflectors that allow a large filling factor (high throughput) at small grazing angles (high energy response). Each detector consists of a cluster of five elements defined with grooves on a single crystal. This arrangement affords some spatial resolution as well as a means of substantial background reduction. Shuttle borne measurements will typically be of 2000 s duration for sources with a flux of 10 to the -12 erg/sq cm-s.
    Keywords: ASTRONOMY
    Type: IEEE Transactions on Nuclear Science (ISSN 0018-9499); NS-31; 786-790
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  • 90
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    Ultraviolet spectra of planetary nebulae. X - Physical conditions in the compact planetary nebula Sw St 1 (1984)
    In:  Other Sources
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    Publication Date: 2011-08-18
    Description: Photoelectric visual and ultraviolet observations of the compact planetary nebula Sw St 1 are analyzed. The electron density, determined from the C III 1907/1909 A line ratio, is N(e) = (1.1 + or - 0.1) x 10 to the 5th/cu cm, consistent with the high emission measure and high critical frequency determined from observations of the thermal radio emission. The C/O abundance ratio in the nebula is found to be N(C)/N(O) = 0.72 + or - 0.1, i.e. the envelope is oxygen-rich, as suggested by the identification of the silicate feature in the 8-13 micron infrared spectrum. Difficulties remain in accurately determining the reddening constant to the nebula and its electron temperature.
    Keywords: ASTRONOMY
    Type: Royal Astronomical Society, Monthly Notices (ISSN 0035-8711); 206; 293-304
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  • 91
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    Detection of silicate emission features in the 8- to 13-micron spectra of main belt asteroids (1983)
    In:  Other Sources
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    Publication Date: 2011-08-18
    Description: A presentation is given of 8.0-13.0 micron spectra (Delta lambda/lambda = 0.02-0.03) for six main belt asteroids, which range from 58 to 220 km in diameter and sample the five principal taxonomic classes (C, S, M, R and E). Narrow, well-defined silicate emission features are present on two of the asteroids, the C-type 19 Fortuna and the M-type 21 Lutetia. No comparable emission features are observed on the S-types 11 Parthenope and 14 Irene, the R-type 349 Dembowska or the E-type 64 Angelina.
    Keywords: ASTRONOMY
    Type: Icarus (ISSN 0019-1035); 56; 393-397
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  • 92
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    Radioastronomical observations of comets IRAS-Araki-Alcock (1983d) and Sugano-Saigusa-Fujikawa (1983e) (1984)
    In:  Other Sources
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    Publication Date: 2011-08-19
    Description: Continuum and spectral-line radio observations of the comets IRAS-Araki-Alcock and Sugano-Saigusa-Fujikawa obtained at a number of observatories during May and June, 1983, are compiled in tables and briefly characterized. The species NH3, H2O, CO, and HCN are considered in detail; visible-range observations of CN are compared; and the implications of the results and the experience gained in performing and coordinating the observations for the detection of important species in other comets, especially Halley's Comet, are explored.
    Keywords: ASTRONOMY
    Type: Icarus (ISSN 0019-1035); 60; 215-220
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  • 93
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    A search at the millijansky level for milli-arcsecond cores in a complete sample of radio galaxies (1984)
    In:  Other Sources
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    Publication Date: 2011-08-19
    Description: A complete sample of 26 extended radio galaxies was observed at 2.29 GHz with the Mark III VLBI system. The fringe spacing was about 3 milli-arcsec, and the detection limit was about 2 millijanskys. Half of the galaxies were found to possess milli-arcsec radio cores. In all but three sources, the nuclear flux density was less than 0.04 of the total flux density. Galaxies with high optical luminosity (less than -21.2) were more likely than less luminous galaxies to contain a detectable milliparcsec radio core (69 percent vs. 20 percent). For objects with arcsec cores, 80 percent were found to have a milli-arcsec core, even though the milli-arcsec object did not always contribute the greater part of the arcsec flux density.
    Keywords: ASTRONOMY
    Type: Astrophysical Journal, Part 1 (ISSN 0004-637X); 284; 519-522
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  • 94
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    The evolution of the infrared emission from the Type II supernova 1980k in NGC 6946 - The dust formation model (1983)
    In:  Other Sources
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    Publication Date: 2011-08-18
    Description: The paper presents 1-4 micron photometry of supernova 1980 k in NGC 6946 obtained over a period of 1 year following the outburst. During the period between 1980 November 1 and December 19, the infrared emission probably originated from the extended atmosphere of the expanding star. The JHKL colors and a 1.3-2.6-micron spectrum observed during this period correspond to those of a blackbody with an average temperature of about 5000 K. Observations around 1981 May 31 showed that the supernova developed an infrared excess after 1980 December. This infrared excess persisted through 1981 October and is consistent with the appearance of thermal emission from about 700 to 900 K dust in addition to a hotter photosphere. The similarity of this behavior to that of the infrared evolution of some novae suggests that dust formation may be occurring in the supernova ejecta. The hypothesis, that the emission arises from preexisting grains in a circumstellar shell which are heated by the supernova outburst, is also consistent with the data.
    Keywords: ASTRONOMY
    Type: Astrophysical Journal, Part 1 (ISSN 0004-637X); 274; 168-174
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  • 95
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    Ultraviolet and optical studies of binaries with luminous cool primaries and hot companions. III - Reticon radial velocities (1983)
    In:  Other Sources
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    Publication Date: 2011-08-18
    Description: Radial velocities for 72 stars, most of them known or suspected binaries with F - K giant-supergiant primaries, are derived from Reticon spectra in the region 6005-6235 A at a scale of 7 km/s per diode. Cross-correlation of the spectra normally produces results accurate to better than 1.0 km/s. Eight new radial velocity variables are found (HR 2786, R Pup, HR 3291, HR 4451, HD 114520, HR 5667, HR 7014, and Nu1 Sgr). Improved orbits are determined for 15 known spectroscopic binaries, and provisional orbits are obtained for seven new spectroscopic binaries.
    Keywords: ASTRONOMY
    Type: Astrophysical Journal Supplement Series (ISSN 0067-0049); 53; 553-571
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  • 96
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    Infrared observations of RS CVn stars (1983)
    In:  Other Sources
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    Publication Date: 2011-08-18
    Description: The paper presents infrared photometry of the RS CVn binary stars AR Lac (1.2-10 microns) and MM Her (1.2-3.5 microns) as they egressed from their primary and secondary eclipses; of the eclipsing systems RS CVn and Z Her at maximum light (1.2-10 microns) and of the non-eclipsing systems UX Ari and HR 1099 (1.2-10 microns). An analysis of these and published V data based on flux ratio diagrams (linear analogues of color-color diagrams) shows that G and K stars supply the infrared light of these systems. In AR Lac, the combined light of a G5-K0 subgiant and either a late F dwarf or an early F subgiant can account for the observed visual and infrared light curves. None of these systems shows infrared emission from circumstellar matter. This result is simply understood: dust grains would not be expected to form in the physical conditions surrounding the subgiant, and the corona and chromosphere (whose properties have been deduced from spectroscopic X-ray observations) should not produce appreciable infrared emission.
    Keywords: ASTRONOMY
    Type: Royal Astronomical Society, Monthly Notices (ISSN 0035-8711); 205; 859-873
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  • 97
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    Ultraviolet high-resolution spectroscopy from the Space Telescope (1983)
    In:  Other Sources
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    Publication Date: 2011-08-18
    Description: The High Resolution Spectrograph is one of five scientific instruments which will be part of the Space Telescope observatory. The spectrograph was designed to take advantage of the imaging and pointing capabilities of the telescope to obtain ultraviolet spectra with spectral resolution comparable to large, ground-based coudeinstruments. Some of the results of the ground-based testing program will be described, along with applications of these properties to future science programs.
    Keywords: ASTRONOMY
    Type: Astronomical Society of the Pacific, Publications (ISSN 0004-6280); 95; 543-549
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  • 98
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    Theoretical studies of the effects of grain noise on photographic stellar astrometry and photometry (1983)
    In:  Other Sources
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    Publication Date: 2011-08-18
    Description: A method of incorporating the effects of photographic emulsion grain noise into digital image centering algorithms is presented which improves the accuracy of the derived stellar positions and magnitudes. Theoretical formulae are then derived for the limiting error of the center, and the photometric parameters. For IIIa-J, this error is 0.2-0.3 mu for bright unsaturated images, which agrees quite well with measurements made with the Yale PDS microdensitometer. It is expected that, with further improvements in the positional accuracy of the PDS, it should be possible to reach the emulsion grain noise limit, providing that emulsion shifts or other large scale errors do not dominate. It is also shown that, with appropriate trimming, marginal distribution image centering algorithms can yield an accuracy only slightly poorer than that obtained with two-dimensional distributions.
    Keywords: ASTRONOMY
    Type: Astronomical Journal (ISSN 0004-6256); 88; 1683-168
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  • 99
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    An improved celestial radio reference frame: JPL 1982-4 (1983)
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    Publication Date: 2011-08-18
    Description: In the development of a celestial radio reference frame, there are now over 100 sources whose relative positions are known with an average uncertainty less than 5 milliarcseconds. These sources are fairly uniformly distributed over the celestial sphere north of -40 deg declination. Their positions are expressed in the new IAU system. This presentation describes the analysis involved in obtaining these results, as well as future plans for linking this system to the JPL planetary ephemerides.
    Keywords: ASTRONOMY
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  • 100
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    New infrared observations of IRS1, IRS3, and the adjacent nebula in the OMC-2 cluster (1984)
    In:  Other Sources
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    Publication Date: 2011-08-18
    Description: Observations of the infrared cluster of low luminosity protostars in Orion Molecular Cloud 2 (OMC2) are reported. Results show that the asymmetric distribution of the extended emission seen about IRS1 is another infrared reflection nebula. Energy distributions show that the spectral shape is fairly constant throughout the nebula which indicates there is little internal extinction within this region. Integrated surface brightness values show that the nebula is 5 times brighter than IRS1 at K. Energy distributions show that IRS1 has a more pronounced ice band absorption feature at 3.1 micron; suggesting that there is more extinction along the direct line of sight to IRS1 than along a line from IRS1 to the scattering grains and then to the observer. The distribution of the extended emission around IRS1 is similar to the reflection nebula seen in NGC 7538 (Werner et al. 1979). The asymmetric shapes of the two nebulae are similar and in each case there is excess extinction along line of sight to the illuminating source.
    Keywords: ASTRONOMY
    Type: Royal Observatory Lab. and Observational Infrared Spectra of Interstellar Dust; p 162-166
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