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  • AIRCRAFT  (76)
  • Fluid Mechanics and Heat Transfer  (74)
  • Biochemistry and Biotechnology
  • 1955-1959  (179)
  • 1950-1954  (10)
Collection
Publisher
Years
Year
  • 1
    Electronic Resource
    Electronic Resource
    New York, NY [u.a.] : Wiley-Blackwell
    Journal of Biochemical and Microbiological Technology and Engineering 1 (1959), S. 1-11 
    ISSN: 0368-1467
    Keywords: Chemistry ; Biochemistry and Biotechnology
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: The effects of pH and concentration on foam separation of the protein bovine serum albumin (BSA) from solution has been studied. All results agree, at least qualitatively, with theory. BSA maximum enrichments were observed at the isoelectric pH and enrichment ratio was found to increase with decreasing protein concentrations.
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  • 2
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    New York, NY [u.a.] : Wiley-Blackwell
    Journal of Biochemical and Microbiological Technology and Engineering 1 (1959), S. 13-25 
    ISSN: 0368-1467
    Keywords: Chemistry ; Biochemistry and Biotechnology
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: Most of the free fluid can generally be expressed from fibrous pulps in a few seconds at 50 lb/in2 if the layer of pulp is kept thinner than 1 in. after it has been pressed, and if the fluid is allowed to run away freely. The need for this time and the frictional properties of many pulps are serious obstacles to the design of any strictly continuous press. Roller presses do not allow enough time, screw expellers create too much friction, continuous centrifuges and some other arrangements are intricate and vulnerable.An intermittent but automatic press which avoids these defects is described. In this the material on a perforated conveyor is pressed by a ram and then moved forward as the ram lifts. One such machine has already been made. An outline is given of the principles on which an improved design will depend.
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  • 3
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    New York, NY [u.a.] : Wiley-Blackwell
    Journal of Biochemical and Microbiological Technology and Engineering 1 (1959), S. 27-36 
    ISSN: 0368-1467
    Keywords: Chemistry ; Biochemistry and Biotechnology
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: Equipment has been developed in which fermentation processes for fastidious, pathogenic micro-organisms can be operated on a pilot-plant scale. Experience has shown the need for the development of concepts, techniques, and equipment meeting more stringent requirements than those ordinarily encountered in the fermentation industry. A system has been developed for the preparation of pure cultures which may be used either for the development of processes or in the preparation of substantial quantities of pure cultures. The equipment includes specially designed valves, fermentors, piping arrangement, and requires special methods of operation in order to maintain pure cultures during growth of the organism. The number of cultures of pathogenic, fastidious micro-organisms contaminated in the systems commonly used in industry is materially greater than the number of contaminated cultures produced in the system described.
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  • 4
    ISSN: 0368-1467
    Keywords: Chemistry ; Biochemistry and Biotechnology
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: A strain of C. purpurea has been isolated which will produce L-tryptophan from indole in submerged culture.The L-tryptophan produced is extracellular and in a free form.Levels of up to 1·5 mg/ml of L-tryptophan have been obtained.
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  • 5
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    New York, NY [u.a.] : Wiley-Blackwell
    Journal of Biochemical and Microbiological Technology and Engineering 1 (1959), S. 37-47 
    ISSN: 0368-1467
    Keywords: Chemistry ; Biochemistry and Biotechnology
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: The results of a study on the surface electric charge carried by fresh-water planktonic algae are used to provide a theory for the flocculation of algae with chemical coagulants. Where it is desirable to remove algae from water, for example from lakes or reservoirs for water supply, or from sewage oxidation ponds, the theory indicates certain practices are desirable to obtain the best removal. It is planned to extend the theory and experimental work to cover the removal of untreated algae from water by filtration through porous granular media, believed to be an adsorptive effect. Separation of different species of algae employing their electrokinetic properties is also described.
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  • 6
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    New York, NY [u.a.] : Wiley-Blackwell
    Journal of Biochemical and Microbiological Technology and Engineering 1 (1959), S. 59-76 
    ISSN: 0368-1467
    Keywords: Chemistry ; Biochemistry and Biotechnology
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: An apparatus is described in which large numbers of algal cultures can be maintained under the following conditions: (1) Constant temperature within the range 5 to 70°C, four different temperatures being maintained simultaneously; (2) uniform illumination at intensities up to 20,000 metre-candles; (3) continuous shaking at variable speed; and (4) aeration under aseptic conditions with mixtures of up to four different gases in any desired proportions.Among other features, thermoregulator heads, flow-meters and heaters for sterile filters, of improved design are described.To illustrate the use of the apparatus, data showing the effects of light intensity and temperature on the growth of Monodus subterraneus are presented.
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  • 7
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    New York, NY [u.a.] : Wiley-Blackwell
    Journal of Biochemical and Microbiological Technology and Engineering 1 (1959), S. 99-113 
    ISSN: 0368-1467
    Keywords: Chemistry ; Biochemistry and Biotechnology
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: The nature of the problem of mould growth on baked products is discussed. Existing information on the reduction of this source of wastage by chemical and irradiation techniques is briefly reviewed, and new experimental evidence is presented relating to the use of these procedures. The effectiveness of ionizing radiations in preventing mould growth is indicated but there are many problems to be considered before it can be regarded as a satisfactorily established technique.
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  • 8
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    New York, NY [u.a.] : Wiley-Blackwell
    Journal of Biochemical and Microbiological Technology and Engineering 1 (1959) 
    ISSN: 0368-1467
    Keywords: Chemistry ; Biochemistry and Biotechnology
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
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  • 9
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    New York, NY [u.a.] : Wiley-Blackwell
    Journal of Biochemical and Microbiological Technology and Engineering 1 (1959), S. 77-98 
    ISSN: 0368-1467
    Keywords: Chemistry ; Biochemistry and Biotechnology
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: Fractions of markedly different protein contents may be obtained by air-classifying flour (in the sub-sieve range) at cut sizes of about 17 and 35 μ respectively. Of these fractions, the fine, 1 (of high protein content), contains fragments of interstitial endosperm protein and small starch granules; the intermediate, 2 (low protein), mainly large starch granules; the coarse, 3, fragments of endosperm cells. The yields and protein contents of the fractions vary with different wheats; the yields of 1 and 2 may be greatly increased through suitably grinding the flour after milling.In general, 1 may be used for raising the protein content of flours deficient in protein to a level suitable for bread-making. The amount of 1 required depends on its protein contents and on whether it came from a hard or soft wheat, the hard wheat fraction having better bread-making qualities. The resulting variation in the proportion of 1 required in the blend causes variation in the proportion of other particulate materials introduced with 1, in which they have become concentrated during the air classification. These include diastatically active agents and finely divided discolouring matter; the level of the former reached in the blend greatly affects its bread-making value. Pre-grinding of the flour may be helpful in this respect.When chlorinated, 2 is potentially useful for making light-structured cakes, but hard English wheats have mainly given less satisfactory results than soft. Under certain conditions, 3, with or without 2, may be better for biscuit-making than the parent flour.
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  • 10
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    Journal of Biochemical and Microbiological Technology and Engineering 1 (1959), S. 129-141 
    ISSN: 0368-1467
    Keywords: Chemistry ; Biochemistry and Biotechnology
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: Applying radio-isotope 32P, the distribution of bacterial cells retained within glass-fibre air sterilization filters was measured. In particular, the time-dependence of the radial as well as the longitudinal distribution was studied. The collection efficiency of glass-fibre was obtained and the experimental result was compared with a theoretical value based upon the sum of interception, inertia and diffusion. Discrepancies could not be accounted for and are similar to those in the literature. An equation was proposed for the estimation of air filter life. This was not completely verified but leads to some suggestive results.
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  • 11
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    Journal of Biochemical and Microbiological Technology and Engineering 1 (1959), S. 207-215 
    ISSN: 0368-1467
    Keywords: Chemistry ; Biochemistry and Biotechnology
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: The mathematical relationship between the throughput of a batch centrifuge and its mechanical characteristics has been applied to the scale-up of one of the steps in virus processing for possible application to the production of vaccines and similar antigens. Slurries that contained a test virus were purified in a laboratory centrifuge. The Q/Σ relationship, developed by Ambler, was used to predict the operating conditions of a larger centrifuge in order to achieve the same clarification of slurry as that produced in the laboratory centrifuge. A correlation between conditions of centrifugation and amount of virus removed from the feed to the centrifuge shows that there is a well-defined Q/Σ value at which significant concentrations of the test virus are sedimented.
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  • 12
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    New York, NY [u.a.] : Wiley-Blackwell
    Journal of Biochemical and Microbiological Technology and Engineering 1 (1959), S. 239-242 
    ISSN: 0368-1467
    Keywords: Chemistry ; Biochemistry and Biotechnology
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
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  • 13
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    Journal of Biochemical and Microbiological Technology and Engineering 1 (1959), S. 243-243 
    ISSN: 0368-1467
    Keywords: Chemistry ; Biochemistry and Biotechnology
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
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  • 14
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    Journal of Biochemical and Microbiological Technology and Engineering 1 (1959), S. 229-238 
    ISSN: 0368-1467
    Keywords: Chemistry ; Biochemistry and Biotechnology
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: An account is given of the construction and operation of a fully automatic apparatus in which the material is kept under agitation in a closed container alternately surrounded by hot and cold alcohol supplied from separate baths. The apparatus has the following applications in microbiology and cell physiology: (1)Extraction of micro-organisms and cell tissues by repeated freezing (F) and thawing (T) at variable temperatures and lengths of FT cycle. Extraction can be controlled automatically or manually. As a practical example of the use of the apparatus a description is given of the extraction of living virulent S. typhi bacteria.(2)Studies of the reactions of living micro-organisms and tissues under varying physical conditions (e.g. high- and low-temperature resistance experiments, osmotic studies, thermal synchronization of bacterial cultures, etc.).(3)If required, the normal gas mixture in the residual air space can without difficulty be replaced by other gases or mixtures such as CO2 or N2.
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  • 15
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    Journal of Biochemical and Microbiological Technology and Engineering 1 (1959), S. 217-228 
    ISSN: 0368-1467
    Keywords: Chemistry ; Biochemistry and Biotechnology
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: A process is described for the extraction of co-enzyme A from dried yeast. It involves cold water extraction, charcoal adsorption followed by pyridine elution, preparation of an acetone power, co-precipitation as the double cuprous complex with glutathione and removal of the glutathione by means of an ion exchange resin.Improvements over previous processes include use of drum dried yeast plus cold extraction resulting in easy filtration and increase of throughput by a factor of three to five, together with the elimination of the ion exchange step formerly thought necessary to remove zine before the co-precipitation stage. Under the best conditions yields represent 30% recovery of the co-enzyme A in the yeast, the product being 90% pure.
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  • 16
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    New York, NY [u.a.] : Wiley-Blackwell
    Journal of Biochemical and Microbiological Technology and Engineering 1 (1959) 
    ISSN: 0368-1467
    Keywords: Chemistry ; Biochemistry and Biotechnology
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
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  • 17
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    Journal of Biochemical and Microbiological Technology and Engineering 1 (1959), S. 244-244 
    ISSN: 0368-1467
    Keywords: Chemistry ; Biochemistry and Biotechnology
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
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  • 18
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    Journal of Biochemical and Microbiological Technology and Engineering 1 (1959), S. 245-259 
    ISSN: 0368-1467
    Keywords: Chemistry ; Biochemistry and Biotechnology
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: The design and construction of a highly sensitive katharometer is described with special reference to the application of the instrument for the precise determination of traces of ethylene by gas chromatography. Factors influencing katharometer sensitivity, and the relative advantages and disadvantages of katharometers as compared with other types of detectors, are discussed.
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  • 19
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    Journal of Biochemical and Microbiological Technology and Engineering 1 (1959), S. 273-288 
    ISSN: 0368-1467
    Keywords: Chemistry ; Biochemistry and Biotechnology
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: An electrophoretic method for the separation of acid polyelectrolytes from proteins in cell extracts is described.A description of the apparatus is given and some results of the separation of extracts from Bordetella pertussis are included.
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  • 20
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    Journal of Biochemical and Microbiological Technology and Engineering 1 (1959), S. 289-295 
    ISSN: 0368-1467
    Keywords: Chemistry ; Biochemistry and Biotechnology
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: An ultrasonic generator was tested at 3 frequencies for its effects on Serratia marcescens during fermentation. The generator controlled foam adequately at 26, 29, and 34 kc/sec at medium aeration rates up to 0·6 ft3/min. Final viable counts were in the same range as those for cultures grown using lard oil as a foam control agent. At 34 kc/sec the final viable counts were slightly higher than those of cultures with lard oil.No harmful effects were evident when large volumes of cultures were exposed to ultrasonic energy during growth.
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  • 21
    ISSN: 0368-1467
    Keywords: Chemistry ; Biochemistry and Biotechnology
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: The feasibility of producing antibiotics by single-stage continuous fermentation was explored by means of a specially designed pilot plant. Both the chloramphenicol and penicillin processes appeared adaptable to such an operation. At dilution rates of 1·0 and 0·5 volume changes per day respectively, yields of from ¼ to ½ of the maxima obtained in batch operation were maintained in the steady-state for more than 2 weeks.
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  • 22
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    Journal of Biochemical and Microbiological Technology and Engineering 1 (1959), S. 393-412 
    ISSN: 0368-1467
    Keywords: Chemistry ; Biochemistry and Biotechnology
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: Kinetic data are needed to develop basic understanding of fermentation processes and to permit rational design of continuous fermentation processes.The kinetics of the fermentation of glucose to lactic acid have been studied at six constant pH levels between 4·5 and 6·0 by measuring the instantaneous rates of bacterial growth and of lactic acid formation throughout each fermentation.It was found that the instantaneous rate of acid formation dP/dt, could be related to the instantaneous rate of bacterial growth dN/dt, and to the bacterial density N, throughout a fermentation at a given pH, by the expression \documentclass{article}\pagestyle{empty}\begin{document}$\frac{{{\rm d}P}}{{{\rm d}t}} = \alpha \frac{{{\rm d}N}}{{{\rm d}t}} + \beta N$\end{document} where the constants α and β are determined by the pH of the fermentation.
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  • 23
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    Journal of Biochemical and Microbiological Technology and Engineering 1 (1959), S. 413-429 
    ISSN: 0368-1467
    Keywords: Chemistry ; Biochemistry and Biotechnology
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: Information on fermentation process kinetics is potentially valuable for the improvement of batch process performance; it is essential for continuous process design. An empirical examination of rate patterns in various fermentations discloses three basic types: (1) ‘growth associated’ products arising directly from the energy metabolism of carbohydrates supplied, (2) indirect products of carbohydrate metabolism and (3) products apparently unrelated to carbohydrate oxidation. Effects of operating variables on the primary kinetic processes, growth, sugar utilization and antibiotic formation, in the penicillin process, illustrate the special nature of this type.
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  • 24
    ISSN: 0368-1467
    Keywords: Chemistry ; Biochemistry and Biotechnology
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: Steady-state and transient equations are derived for continuous-flow fermentation processes. Analytical as well as graphical methods for predicting from batch data the performance of single- or multi-stage continuous fermentations are developed. The criteria for stability are also examined. Actual experimental measurements of continuous lactic acid fermentations conducted at controlled pH levels agree with the theory developed.
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  • 25
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    Journal of Biochemical and Microbiological Technology and Engineering 1 (1959), S. 379-392 
    ISSN: 0368-1467
    Keywords: Chemistry ; Biochemistry and Biotechnology
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: A pilot plant unit for continuous cultivation of hyphaeforming micro-organisms, providing for a uniform flow velocity in fermentations on suspension media with a massive growth of mycelium, is described. For the maintenance of aseptic conditions, over-pressre of air is maintained in the whole equipment. This equipment has been used for studies of the continuous biosynthesis of streptomycin. A three-stage fermentation proved the most advantageous. The first stage serves for multiplication of the inoculum; the second and third for the formation of the antibiotic. The system was maintained for 300-400 h with yields amounting to 2,000-2,500 u. of streptomycin/ml without any signs of contamination or degeneration of the growing culture.
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  • 26
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    Journal of Biochemical and Microbiological Technology and Engineering 1 (1959) 
    ISSN: 0368-1467
    Keywords: Chemistry ; Biochemistry and Biotechnology
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
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  • 27
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    Journal of Biochemical and Microbiological Technology and Engineering 1 (1959), S. 143-162 
    ISSN: 0368-1467
    Keywords: Chemistry ; Biochemistry and Biotechnology
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: An analysis of the organic constituents of whole, domestic sewage was made by analysing four physically separated fractions. Settlement, centrifuging and filtration were used to obtain one liquid and three solid fractions. Concentration of the filtrate was achieved by freeze-drying with only minor changes in composition. The average concentration of organic carbon in fresh, whole domestic sewage was 310 p.p.m., of which about 70 per cent was in suspension. Eight classes of compounds were found, on analysis, to comprise about 75 per cent of the organic carbon in whole sewage and of the soluble organic carbon 80 per cent was distributed between five groups. Using chromatographic methods the concentrations of four volatile acids were determined and the presence of other acids was detected. Similarly, seven of the soluble sugars and eight present in hydrolysed suspended solids have been identified. The probable nature of some of the compounds unaccounted for is discussed.
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  • 28
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    Journal of Biochemical and Microbiological Technology and Engineering 1 (1959), S. 163-172 
    ISSN: 0368-1467
    Keywords: Chemistry ; Biochemistry and Biotechnology
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: The influence of mechanical agitation in aerobic fermentations is felt mainly through increased aeration efficiency. For yeast propagations in which oxygen supply is abundant - and presumably not limiting to growth - a specific, but limited, effect of fluid agitation on growth rate has been demonstrated. The improved growth rate is attributed primarily to better mixing of the entire fluid mixture rather than to improved cell-fluid mass transfer.
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  • 29
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    Journal of Biochemical and Microbiological Technology and Engineering 1 (1959), S. 115-127 
    ISSN: 0368-1467
    Keywords: Chemistry ; Biochemistry and Biotechnology
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: Information on a reliable method for determining the nutritive value of existing and experimental peptones is lacking in the literature. To overcome this handicap, a method for comparative evaluation of microbiological peptones has been developed.The method is based on measuring the growth of eight carefully selected, fastidious, test cultures. The cultures are grown in presence and absence of yeast extract in an inorganic basal medium containing test peptone and a low and high level of glucose.Statistical analysis of replicate peptone evaluations of six peptones, conducted over a period of six months, shows that 95 per cent confidence limits for this method are ± 2·5 to 7·9 per cent of the mean.Four criteria are employed for determining the overall performance of 12 widely used, commercial peptones.The method is very sensitive for detecting differences between batches of commercial peptones. With the aid of this method a new peptone ‘N-Z-Amine YT’ has been developed. Considering performance and relative cost, this peptone is the most economical of the peptones evaluated.
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  • 30
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    Journal of Biochemical and Microbiological Technology and Engineering 1 (1959), S. 173-184 
    ISSN: 0368-1467
    Keywords: Chemistry ; Biochemistry and Biotechnology
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: A study of factors affecting the reproducibility and yields in cultivations of H. pertussis (the whooping cough organism). The search for suitable media led to the development of a new kind of blood medium suitable for pre-cultures. Sterility of the blood additive could be ensured by filtration, and contamination on starting the freeze-dried cells was avoided by the use of a special kind of ampoule.In the course of studies of different cultivation techniques a 6,000 ml ‘pulsaerator’ was found to be ideal for the preparation of ordinary small batches. Inoculation density, aeration and other factors affecting the yield were studied and a culture cycle suitable for preparing 500 l. batches was developed.
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  • 31
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    Journal of Biochemical and Microbiological Technology and Engineering 1 (1959), S. 185-205 
    ISSN: 0368-1467
    Keywords: Chemistry ; Biochemistry and Biotechnology
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: The mathematical theory of the sedimentation type of centrifuge is developed in terms of unhindered settling of a single particle that has reached equilibrium velocity. From this is derived the sigma value for several of the different forms of sedimentation type centrifuge which is the calculated equivalent area of a settling tank theoretically capable of doing the same amount of work in a unit gravitational field. The limitations controlling the accuracy of scale up between centrifuges of similar geometry and between centrifuges of substantially different geometry are discussed.
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  • 32
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    Journal of Biochemical and Microbiological Technology and Engineering 1 (1959), S. 261-271 
    ISSN: 0368-1467
    Keywords: Chemistry ; Biochemistry and Biotechnology
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: During the biosynthetic production of chlortetracycline on a medium with sucrose, soy meal, corn steep extract, sodium chloride, ammonium sulphate, calcium carbonate and beet molasses, the amount of nucleic acids synthesized by the culture and the maximum respiration of the culture is determined by the amount of inorganic phosphate in the original medium. Chlortetracycline production does not start until all the inorganic phosphate has been consumed. The adverse influence of increased amounts of inorganic phosphate upon production of chlortetracycline is more apparent in flasks on a shaking machine than in agitated and aerated fermentation tanks with higher oxygen transfer numbers.
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  • 33
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    New York, NY [u.a.] : Wiley-Blackwell
    Journal of Biochemical and Microbiological Technology and Engineering 1 (1959), S. 297-302 
    ISSN: 0368-1467
    Keywords: Chemistry ; Biochemistry and Biotechnology
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: A simple, rugged and compact automatic feed control attachment for the laboratory-size glass circulating evaporator has been designed and constructed. Experience has demonstrated that this apparatus operates satisfactorily with a variety of aqueous biological extracts and solutions having resistivity values of 50,000 ohm-in. or less. The device in adaptable to other evaporators and stills.
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  • 34
    Electronic Resource
    Electronic Resource
    New York, NY [u.a.] : Wiley-Blackwell
    Journal of Biochemical and Microbiological Technology and Engineering 1 (1959), S. 303-309 
    ISSN: 0368-1467
    Keywords: Chemistry ; Biochemistry and Biotechnology
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: A description of the cultivation of Rhodospirillum rubrum in 1,000 and 3,000 l. fermentors fitted with a special illumination device, and a discussion of the results.
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  • 35
    Electronic Resource
    Electronic Resource
    New York, NY [u.a.] : Wiley-Blackwell
    Journal of Biochemical and Microbiological Technology and Engineering 1 (1959) 
    ISSN: 0368-1467
    Keywords: Chemistry ; Biochemistry and Biotechnology
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Type of Medium: Electronic Resource
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  • 36
    Electronic Resource
    Electronic Resource
    New York, NY [u.a.] : Wiley-Blackwell
    Journal of Biochemical and Microbiological Technology and Engineering 1 (1959), S. 311-324 
    ISSN: 0368-1467
    Keywords: Chemistry ; Biochemistry and Biotechnology
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: Novobiocin fermentations in 20 l. baffled fermentors were studied as a function of the size and speed of the dual four-bladed flat-blade turbines used. Power input and sulphite oxidation rate measurements were made. The courses of pH, sugar utilization, mycelial dry weight, carbon dioxide evolution and antibiotic titer were determined. Optimum antibiotic yields were achieved at a power input of 0·5 h.p./100 gal, equivalent to a sulphite oxidation rate of 110 mmoles O2/l.h, when the impeller diameters were 29 per cent or 39 per cent of the tank diameter. A power input of 0·75 h.p./100 gal, equivalent to a sulphite oxidation rate of 160 mmoles O2/l.h, was required for equivalent results with the impeller diameter 49 per cent of the tank diameter. Some explanations of the lack of equivalent results with the large impeller are discussed.
    Additional Material: 7 Ill.
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  • 37
    Electronic Resource
    Electronic Resource
    New York, NY [u.a.] : Wiley-Blackwell
    Journal of Biochemical and Microbiological Technology and Engineering 1 (1959), S. 325-334 
    ISSN: 0368-1467
    Keywords: Chemistry ; Biochemistry and Biotechnology
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: Probability theory has been applied to the analysis of bacterial distribution within a fibrous air sterilization filter. For a long filter layer, to which the so-called ‘log-penetration’ law is no longer applicable, the probability theory is considered to be effective in interpreting the distribution data.The effects of the diameter, volume fraction and moisture content of the glass-fibre on the longitudinal distribution of bacterial cells, were studied. The distribution was estimated beyond the experimental data points. This estimation will be of use for predicting the ‘life’ of an air sterilization filter.
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  • 38
    Electronic Resource
    Electronic Resource
    New York, NY [u.a.] : Wiley-Blackwell
    Journal of Biochemical and Microbiological Technology and Engineering 1 (1959), S. 349-357 
    ISSN: 0368-1467
    Keywords: Chemistry ; Biochemistry and Biotechnology
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: The equations of Monod that describe the course of bacterial population growth and substrate concentration during continuous culturing are usually analysed with reference to steady-state conditions. These equations are analysed to give information on the course of bacterial population growth from inoculation to the achievement of a steady-state condition. For common values of certain parameters occurring in Monod's development, growth is well approximated by an exponential law (logarithmic phase) which depends on: (a) the maximum specific growth-rate constant for the organism and medium concerned, and (b) the constant dilution rate.
    Additional Material: 1 Ill.
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  • 39
    ISSN: 0368-1467
    Keywords: Chemistry ; Biochemistry and Biotechnology
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: The effect of agitation on the rate of acid formation by the microaerophilic organism Lactobacillus delbrueckii was studied. Fermentations were conducted at constant temperature and pH, and with the continuous addition of a nutrilite source. The range of agitator speeds was from 85 to 720 rev/min.The acid formation rate was found to increase with increasing agitator speeds and decrease with decreasing speeds if corn-steep liquor was the nutrilite source. No effect of agitation was observed with yeast extract as the nutrilite source.The data from corn-steep liquor media were found to be consistent with a mass transfer mechanism, but did not warrant a conclusion as to the specific nature of the effect of agitation. It was concluded, however, that the effect of agitation on the acid formation rate was at most very small.
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  • 40
    Publication Date: 2012-05-30
    Keywords: AIRCRAFT
    Format: text
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  • 41
    Publication Date: 2019-05-11
    Description: Heat & impact test on insulated & uninsulated fuse mechanism of ballistic missile in reentry aerodynamic heating
    Keywords: AIRCRAFT
    Type: NASA-MEMO-12-5-58L
    Format: text
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  • 42
    Publication Date: 2019-05-11
    Description: Stability and control of flat surface wing- fuselage combination at subsonic speed - effect of wing leading edge sweepback
    Keywords: AIRCRAFT
    Type: NASA-MEMO-3-5-59A
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  • 43
    Publication Date: 2019-05-11
    Description: External stream effects on isentropic plug-type nozzle performance at mach 2.0, 1.8, and 1.5
    Keywords: AIRCRAFT
    Type: NASA-MEMO-2-17-59E
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  • 44
    Publication Date: 2019-05-11
    Description: Transonic static aerodynamic characteristics of blunt cone cylinder body with flared afterbodies of various angles and base areas
    Keywords: AIRCRAFT
    Type: NASA-TM-X-106
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  • 45
    Publication Date: 2019-05-11
    Description: Subsonic aerodynamics of several blunt, lifting, atmospheric-entry shapes
    Keywords: AIRCRAFT
    Type: NASA-MEMO-12-24-58A
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  • 46
    Publication Date: 2019-05-11
    Description: Axisymmetric double cone compression inlet
    Keywords: AIRCRAFT
    Type: NASA-MEMO-12-22-58E
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  • 47
    Publication Date: 2019-05-11
    Description: Effect of boundary layer removal on total pressure recovery - circular internal compression inlets with translating centerbodies
    Keywords: AIRCRAFT
    Type: NASA-MEMO-2-19-59A
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  • 48
    Publication Date: 2019-05-11
    Description: Effect of camber on aerodynamic characteristics of ogive-circular-cylindrical body at mach 2.01
    Keywords: AIRCRAFT
    Type: NASA-TM-X-56
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  • 49
    Publication Date: 2019-05-11
    Description: Subsonic flight characteristics of flat-top hypersonic-boost glide airplane model with arrowhead wing
    Keywords: AIRCRAFT
    Type: NASA-TM-X-193
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  • 50
    Publication Date: 2019-05-11
    Description: Effects of wing-crank, leading-edge chord extensions & horizontal-tail height on longitudinal stability of swept-wing models
    Keywords: AIRCRAFT
    Type: NASA-TM-X-92
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  • 51
    Publication Date: 2019-05-11
    Description: Aerodynamic characteristics of flat-bottom wing- body combinations at mach 3.0 and 3.5
    Keywords: AIRCRAFT
    Type: NASA-MEMO-1-2-59E
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  • 52
    Publication Date: 2019-05-11
    Description: Performance and static stability of supersonic aircraft configuration with lift interference
    Keywords: AIRCRAFT
    Type: NASA-MEMO-1-8-59A
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  • 53
    Publication Date: 2019-05-11
    Description: Static longitudinal stability characteristics of blunted glider reentry configuration
    Keywords: AIRCRAFT
    Type: NASA-TM-X-222
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  • 54
    Publication Date: 2019-05-11
    Description: Low-speed static longitudinal and lateral characteristics of delta-wing model with fixed and free-floating canard surfaces
    Keywords: AIRCRAFT
    Type: NASA-TM-X-120
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  • 55
    Publication Date: 2019-05-11
    Description: Static longitudinal aerodynamics of wing and blunt body shapes for use as reentry configurations at hypersonic speed and angles of attack up to 90-deg
    Keywords: AIRCRAFT
    Type: NASA-TM-X-65
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  • 56
    Publication Date: 2019-05-11
    Description: Static stability and control characteristics of aircraft model with tail surfaces outboard of wing tips
    Keywords: AIRCRAFT
    Type: NASA-TM-X-47
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  • 57
    Publication Date: 2019-05-11
    Description: Thrust modulation techniques - cold flow tests of three variable-throat-area convergent-divergent nozzles
    Keywords: AIRCRAFT
    Type: NASA-TM-X-42
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  • 58
    Publication Date: 2019-05-11
    Description: Effects of wing vertical location on stability and control of canard aircraft at supersonic speeds
    Keywords: AIRCRAFT
    Type: NASA-TM-X-44
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  • 59
    Publication Date: 2019-05-11
    Description: Inlets with throat and cowl bypasses for matching a two-dimensional variable geometry
    Keywords: AIRCRAFT
    Type: NASA-MEMO-2-6-59E
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  • 60
    Publication Date: 2019-05-11
    Description: Low-speed longitudinal static stability & control characteristics of aircraft with swept wings & tail surfaces outboard of wing tips
    Keywords: AIRCRAFT
    Type: NASA-MEMO-6-11-59L
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  • 61
    Publication Date: 2019-05-30
    Description: Transonic wind tunnel study of static longitudinal and lateral stability and control characteristics and drag rise of fighter aircraft
    Keywords: AIRCRAFT
    Type: NASA-MEMO-12-14-58L
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  • 62
    Publication Date: 2019-05-29
    Description: Comparison of control-fixed stability derivatives for two supersonic fighters as determined from flight and wind tunnel tests
    Keywords: AIRCRAFT
    Type: NASA-MEMO-2-3-59L
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  • 63
    Publication Date: 2019-06-27
    Description: Development of aircraft control system with high performance electrically controlled and mechanically operated hydraulic valves for precise flight operation
    Keywords: AIRCRAFT
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  • 64
    Publication Date: 2019-06-27
    Description: Pressure distribution on trapezoidal wing of canard aircraft model in supersonic pressure tunnel - tables
    Keywords: AIRCRAFT
    Type: NASA-TM-X-140
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  • 65
    Publication Date: 2019-08-17
    Description: Measurements of the statistical properties of the fluctuating wall pressure produced by a subsonic turbulent boundary layer are described. The measurements provide additional information about the structure of the turbulent boundary layer; they are applicable to the problems of boundary-layer induced noise inside an airplane fuselage and to the generation of waves-on water. The spectrum of the wall pressure is presented in dimensionless form. The ratio of the root-mean-square wall pressure to the free-stream dynamic pressure is found to be a constant square root of bar P(sup 2)/q(sub infinity) = 0.006 independent of Mach number and Reynolds number. In addition, space- time correlation measurements in the stream direction show that pressure fluctuations whose scale is greater than or equal to 0.3 times the boundary-layer thickness are convected with the convection speed U(sub c) = 0.82U(sub infinity) where U(infinity) is the free-stream velocity and have lost their identity in a distance approximately equal to 10 boundary-layer thicknesses.
    Keywords: Fluid Mechanics and Heat Transfer
    Type: NASA-MEMO-3-17-59W
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  • 66
    Publication Date: 2019-08-17
    Description: Approximate analytical solutions are presented for two-dimensional and axisymmetric hypersonic flow over slender power law bodies. Both zero order (M approaches infinity) and first order (small but nonvanishing values of 1/(M(Delta)(sup 2) solutions are presented, where M is free-stream Mach number and Delta is a characteristic slope. These solutions are compared with exact numerical integration of the equations of motion and appear to be accurate particularly when the shock is relatively close to the body.
    Keywords: Fluid Mechanics and Heat Transfer
    Type: NASA-TR-R-15
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  • 67
    Publication Date: 2019-08-17
    Description: An experimental investigation of the mixing of two coaxial gas streams was conducted over a range of subsonic jet Mach numbers and temperatures. Three configurations were investigated. One had no innerbody in the primary or inner pipe and was designed to give flat velocity profiles at the exit of the primary pipe. The other two configurations had innerbodies in the primary pipe. These were designed to give velocity profiles similar to those existing at the inlet of propulsive systems such as afterburners. Curves of axial velocity and temperature profiles across the radius are presented at various axial stations. For the two configurations with the innerbody, data are shown at stations out to approximately 8 primary-pipe diameters from the exit of the primary pipe. For the flat-velocity-profile configuration, data are shown at distances extending downstream at 22 primary-pipe diameters from the exit of the primary pipe.
    Keywords: Fluid Mechanics and Heat Transfer
    Type: NASA-MEMO-12-21-58E , L-104
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  • 68
    Publication Date: 2019-08-17
    Description: Techniques which have been used for finishing and quantitatively specifying surface roughness on boundary-layer-transition models are reviewed. The appearance of a surface as far as roughness is concerned can be misleading when viewed either by the eye or with the aid of a microscope. The multiple-beam interferometer and the wire shadow method provide the best simple means of obtaining quantitative measurements.
    Keywords: Fluid Mechanics and Heat Transfer
    Type: NASA-MEMO-1-19-59A , A-133
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  • 69
    Publication Date: 2019-08-17
    Description: Wind-tunnel tests have been made to determine the location of the boundary-layer transition on three hemispheres having surface roughness (absolute) values of 50, 580, and 2760 microinches. After the initial test run of the smoothest (50 microinch) hemisphere, holes ranging in depth from 1500 to 2500 microinches were noticed in the meridian where transition was observed. The holes were believed to be caused by particles in the air stream. Shadowgraph pictures were obtained of all hemispheres and surface temperature measurements were made on one hemisphere (580 microinches). Tests at high Reynolds numbers (6.4 to 7.5 x 10(exp 6) and a Mach number of 2.48 did not indicate any transition on the 50-microinch surface hemisphere before the holes appeared. However, after the holes were noticed, transition locations as low as 50 deg(measured from the stagnation point) were observed at similar Reynolds numbers and Mach numbers. It is felt the transition resulted from the holes. Similar transition locations of approximately 500 were also observed in the tests of hemispheres with surface roughness values of 580 and 2760 microinches at high Reynolds numbers (6.4 x 10(exp 6) to 7.5 x 10(exp 6)) and at a Mach number of 2.48. The results at a Mach number of 2.48 indicate that an absolute surface roughness value of 50 microinches was not critical in causing boundary-layer tran sition at Reynolds numbers of 6.4 to 7.5 x 10(exp 6) whereas roughness values of 580 and 2760 microinches were greater than critical. Transition Reynolds numbers based on momentum thickness, R(sub phi T) varied over a range of approximately 480 to 300 for transition locations, alpha, on the hemisphere from 880 to 410 (measured from the stagnation point). A maximum value of R(phi) of 660 (based on alpha = 90 deg) was obtained with the 50-microinch surface hemisphere at a Mach number of 2.48.
    Keywords: Fluid Mechanics and Heat Transfer
    Type: NASA-MEMO-12-25-58A , A-105
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  • 70
    Publication Date: 2019-08-17
    Description: Tests were made on a 10-foot-diameter hemispherical nose at Reynolds numbers up to 10 x 10(exp 6) and at a maximum Mach number of about 0.1 to determine the effects of a highly favorable pressure gradient on boundary-layer transition caused by roughness. Both two-dimensional and three-dimensional roughness particles were used, and the transition of the boundary layer was determined by hot-wire anemometers. The roughness Reynolds number for transition R(sub k,t) caused by three-dimensional particles such as Carborundum grains, spherical particles, and rimmed craters was found. The results show that for particles immersed in the boundary layer, R(sub k,t) is independent of the particle size or position on the hemispherical nose and depends mainly on the height-to-width ratio of the particle. The values of R(sub k,t) found on the hemispherical nose compare closely with those previously found on a flat plate and on airfoils with roughness. For two-dimensional roughness, the ratio of roughness height to boundary-layer displacement thickness necessary to cause transition was found to increase appreciably as the roughness was moved forward on the nose. Also included in the investigation were studies of the spread of turbulence behind a single particle of roughness and the effect of holes such as pressure orifices.
    Keywords: Fluid Mechanics and Heat Transfer
    Type: NASA-MEMO-2-8-59L , L-172
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  • 71
    Publication Date: 2019-08-17
    Description: A theory is derived for determining the loads and motions of a deeply immersed prismatic body. The method makes use of a two-dimensional water-mass variation and an aspect-ratio correction for three-dimensional flow. The equations of motion are generalized by using a mean value of the aspect-ratio correction and by assuming a variation of the two-dimensional water mass for the deeply immersed body. These equations lead to impact coefficients that depend on an approach parameter which, in turn, depends upon the initial trim and flight-path angles. Comparison of experiment with theory is shown at maximum load and maximum penetration for the flat-bottom (0 deg dead-rise angle) model with bean-loading coefficients from 36.5 to 133.7 over a wide range of initial conditions. A dead-rise angle correction is applied and maximum-load data are compared with theory for the case of a model with 300 dead-rise angle and beam-loading coefficients from 208 to 530.
    Keywords: Fluid Mechanics and Heat Transfer
    Type: NASA-MEMO-2-10-59L , L-152
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  • 72
    Publication Date: 2019-08-17
    Description: An analytical heat transfer solution is derived and evaluated for the general case of a turbulently flowing liquid metal which suddenly encounters a step-function boundary temperature in a channel system. Local Nusselt moduli, dimensionless mixed-mean fluid temperatures, and arithmetic-mean Nusselt moduli are given as functions of Reynolds and Prandtl moduli and a dimensionless axial-distance modulus. These solutions are compared with known solutions of more specific systems as well as with a set of experimental liquid-metal heat transfer data for a thermal entrance region.
    Keywords: Fluid Mechanics and Heat Transfer
    Type: NASA-MEMO-2-5-59W , W-105
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  • 73
    Publication Date: 2019-08-17
    Description: Heat-transfer and pressure-drop data were obtained experimentally for the gas side of a liquid-metal to air, compact finned-tube heat exchanger. The heat exchanger was fabricated from 0.185-inch Inconel tubing in an inline array. The fins were made of 310 stainless-steel- clad copper with a total thickness of 0.010 inch, and the fin pitch was 15.3 fins per inch. The liquid used as the heating medium was sodium. The heat-exchanger inlet gas temperature was varied from 5100 to 1260 R by burning JP fuel for airflow rates of 0.4 to 10.5 pounds per second corresponding to an approximate Reynolds number range of 300 to 9000. The sodium inlet temperature was held at 1400 R with the exception of a few runs taken at 1700 and 1960 R. The maximum ratio of surface temperature to air bulk temperature was 1.45. Friction-factor data with heat transfer were best represented by a single line when the density and viscosity of Reynolds number were evaluated at the average film temperature. At the lower Reynolds numbers reported, the friction data with heat transfer plotted slightly above the friction data without heat transfer. The density of the friction factor was calculated at the average bulk temperature. Heat-transfer results of this investigation were correlated by evaluating the physical properties of air (specific heat, viscosity, and thermal conductivity) at the film temperature.
    Keywords: Fluid Mechanics and Heat Transfer
    Type: NASA-MEMO-4-30-59E
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  • 74
    Publication Date: 2019-08-17
    Description: Three numerical solutions of the partial differential equations describing the compressible laminar boundary layer are obtained by the finite difference method described in reports by I. Flugge-Lotz, D.C. Baxter, and this author. The solutions apply to steady-state supersonic flow without pressure gradient, over a cold wall and over an adiabatic wall, both having transpiration cooling upstream, and over an adiabatic wall with upstream cooling but without upstream transpiration. It is shown that for a given upstream wall temperature, upstream transpiration cooling affords much better protection to the adiabatic solid wall than does upstream cooling without transpiration. The results of the numerical solutions are compared with those of approximate solutions. The thermal results of the finite difference solution lie between the results of Rubesin and Inouye, and those of Libby and Pallone. When the skin-friction results of one finite difference solution are used in the thermal analysis of Rubesin and Inouye, improved agreement between the thermal results of the two methods of solution is obtained.
    Keywords: Fluid Mechanics and Heat Transfer
    Type: NASA-MEMO-2-26-59A
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  • 75
    Publication Date: 2019-08-17
    Description: The measured static-pressure distributions at the model surface and in the surrounding flow field are presented for a basic parabolic-arc body having a fineness ratio of 14 and for three additional bodies obtained by modifying the basic parabolic-arc body along the middle portion of the body length by adding a bump, by indenting, or by quadripole shaping. The data were obtained with the various bodies at zero angle of attack. The Mach number varied from 0.80 to 1.20 with a corresponding Reynolds number (based on body length) variation of 27 x 10(exp 6) to 38 x 10(exp 6). The data are subject to tunnel-wall interference and do not represent free-air conditions.
    Keywords: Fluid Mechanics and Heat Transfer
    Type: NASA-MEMO-1-22-59A
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  • 76
    Publication Date: 2019-08-17
    Description: An investigation of expanded duct sections and the effect of their design parameters on flow distortion over a duct Mach number range of 0.19 to 0.67 was conducted in the small tunnel facility of the Lewis Research Center. The parameters investigated were: (1) entrance angle of expanded section, (2) length of expanded section, (3) area ratio of expanded section, (4) location of expanded section relative to the engine face, and (5) the use of screens of varying solidities and mesh. Expansion half-angles of deg, 15 deg, and 30 deg reduced the total-pressure distortions induced in the duct. The larger expansion angles reduced circumferential distortion more effectively than radial distortion. However, the half-angle of 15 deg appeared to be optimum for reducing both radial and circumferential distortions while still maintaining a high total-pressure recovery. Increasing the expanded-section area ratio and increasing the expanded-section lengths with-the 150 expansion half-angle led to less total-pressure distortion with no appreciable loss in pressure recovery. Screens incorporated in the expanded section indicated that 22.2-percent- solidity screens decreased distortion still further.while 37.3-percent- solidity screens generally increased distortion above that of a constant- area duct incorporating the same solidity screen.
    Keywords: Fluid Mechanics and Heat Transfer
    Type: NASA-MEMO-1-9-59E
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  • 77
    Publication Date: 2019-08-17
    Description: Hot-wire anemometer measurements were made of several statistical properties of approximately homogeneous and isotropic fields of turbulence and temperature fluctuations generated by a warm grid in a uniform airstream sent through a 4-to-1 contraction. These measurements were made both in the contraction and in the axisymmetric domain farther downstream. In addition to confirming the well-known turbulence anisotropy induced by strain, the data show effects on the skewnesses of both longitudinal velocity fluctuation (which has zero skewness in isotropic turbulence) and its derivative. The concomitant anisotropy in the temperature field accelerates the decay of temperature fluctuations.
    Keywords: Fluid Mechanics and Heat Transfer
    Type: NASA-MEMO-5-5-59W
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  • 78
    Publication Date: 2019-08-17
    Description: A procedure based on the method of similar solutions is presented by which the skin friction, heat transfer, and boundary-layer thickness in a laminar hypersonic flow with pressure gradient may be rapidly evaluated if the pressure distribution is known. This solution, which at present is. restricted to power-law variations of pressure with surface distance, is presented for a wide range of exponents in the power law corresponding to both favorable and adverse pressure gradients. This theory has been compared to results from heat-transfer experiments on blunt-nose flat plates and a hemisphere cylinder at free-stream Mach numbers of 4 and 6.8. The flat-plate experiments included tests made at a Mach number of 6.8 over a range of angle of attack of +/- 10 deg. Reasonable agreement of the experimental and theoretical heat-transfer coefficients has been obtained as well as good correlation of the experimental results over the entire range of angle of attack studied. A similar comparison of theory with experiment was not feasible for boundary-layer-thickness data; however, the hypersonic similarity theory was found to account satisfactorily for the variation in boundary-layer thickness due to local pressure distribution for several sets of measurements.
    Keywords: Fluid Mechanics and Heat Transfer
    Type: NASA-MEMO-5-24-59L
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  • 79
    facet.materialart.
    Unknown
    In:  CASI
    Publication Date: 2019-08-17
    Description: A simplified analysis is made of ablation cooling near the stagnation point of a two-dimensional or axisymmetric body which occurs as the body vaporizes directly from the solid state. The automatic shielding mechanism Is discussed and the important thermal properties required by a good ablation material are given. The results of the analysis are given in terms of dimensionless parameters.
    Keywords: Fluid Mechanics and Heat Transfer
    Type: NASA-TR-R-9
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  • 80
    Publication Date: 2019-08-16
    Description: The momentum integral equations are derived for the boundary layer on an arbitrary curved surface, using a streamline coordinate system. Computations of the turbulent boundary layer on a slightly yawed cone are made for a Prandtl number of 0.729, wall to free-stream temperature ratios of 1/2, 1, and 2, and Mach numbers from 1 to 4. Deflection of the fluid in the boundary layer from outer stream direction, local friction coefficient, displacement surface, lift coefficient, and pitching-moment coefficient are presented.
    Keywords: Fluid Mechanics and Heat Transfer
    Type: NASA-TR-R-7
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  • 81
    Publication Date: 2019-08-16
    Description: Measurements of the heat transfer from a horizontal cylinder rotating about its axis have been made with oil as the surrounding fluid to provide an addition to the heat-transfer results for this system heretofore available only for air. The results embrace a Prandtl number range from about 130 to 660, with Reynolds numbers up to 3 x 10(exp 4), and show an increasing dependence of free-convection heat transfer on rotation as the Prandtl number is increased by reducing the oil temperature. Some correlation of this effect, which agrees with the prior results for air, has been achieved. At higher rotative speeds the flow becomes turbulent, the free- convection effect vanishes, and the results with oil can be correlated generally with those for air and with mass-transfer results for even higher Prandtl numbers. For this system, however, the analogy calculations which have successfully related the heat transfer to the friction for pipe flows at high Prandtl numbers fail.
    Keywords: Fluid Mechanics and Heat Transfer
    Type: NASA-MEMO-4-22-59W , W-103
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  • 82
    Publication Date: 2019-08-16
    Description: The effects of Mach number and surface-roughness variation on boundary-layer transition were studied using fin-stabilized hollow-tube models in free flight. The tests were conducted over the Mach number range from 2.8 to 7 at a nominally constant unit Reynolds number of 3 million per inch, and with heat transfer to the model surface. A screwthread type of distributed two-dimensional roughness was used. Nominal thread heights varied from 100 microinches to 2100 microinches. Transition Reynolds number was found to increase with increasing Mach number at a rate depending simultaneously on Mach number and roughness height. The laminar boundary layer was found to tolerate increasing amounts of roughness as Mach number increased. For a given Mach number an optimum roughness height was found which gave a maximum laminar run greater than was obtained with a smooth surface.
    Keywords: Fluid Mechanics and Heat Transfer
    Type: NASA-MEMO-1-20-59A
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  • 83
    Publication Date: 2019-08-16
    Description: The fluid-dynamic characteristics of flat plates, 5 deg and 10 deg wedges, and 5 deg and 10 deg cones have been investigated at Mach numbers from 16.3 to 23.9 in helium flow. The flat-plate results are for a leading-edge Reynolds number range of 584 to 19,500 and show that the induced pressure distribution is essentially linear with the hypersonic viscous interaction parameter bar X within the scope of this investigation. It is also shown that the rate at which the induced pressure varies with bar X is a linear function of the leading-edge Reynolds number. The wedge and cone results show that as the flow-deflection angle increases, the induced-pressure effects decrease and the measured pressures approach those predicted by inviscid shock theory.
    Keywords: Fluid Mechanics and Heat Transfer
    Type: NASA-MEMO-5-8-59L
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  • 84
    Publication Date: 2019-08-16
    Description: Hypersonic-slender-body theory, in the limit as the free-stream Mach number becomes infinite, is used to find the effect of slightly perturbing the surface of slender two-dimensional and axisymmetric power law bodies, The body perturbations are assumed to have a power law variation (with streamwise distance downstream of the nose of the body). Numerical results are presented for (1) the effect of boundary-layer development on two dimensional and axisymmetric bodies, (2) the effect of very small angles of attack (on tow[dimensional bodies), and (3) the effect of blunting the nose of very slender wedges and cones.
    Keywords: Fluid Mechanics and Heat Transfer
    Type: NASA-TR-R-45
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  • 85
    Publication Date: 2019-08-16
    Description: Heat-transfer coefficients and pressure distributions were obtained on a 4-inch-diameter flat-face cylinder in the Langley Unitary Plan wind tunnel. The measured stagnation heat-transfer coefficient agrees well with 55 percent of the theoretical value predicted by the modified Sibulkin method for a hemisphere. Pressure measurements indicated the dimensionless velocity gradient parameter r du\ a(sub t) dx, where x=0 at the stagnation point was approximately 0.3 and invariant throughout the Mach number range from 2.49 to 4.44 and the Reynolds number range from 0.77 x 10(exp 6) to 1.46 x 10(exp 6). The heat-transfer coefficients on the cylindrical afterbody could be predicted with reasonable accuracy by flat-plate theory at an angle of attack of 0 deg. At angles of attack the cylindrical afterbody stagnation-line heat transfer could be computed from swept-cylinder theory for large distances back of the nose when the Reynolds number is based on the distance from the flow reattachment points.
    Keywords: Fluid Mechanics and Heat Transfer
    Type: NASA-TM-X-19
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  • 86
    Publication Date: 2019-08-15
    Description: Heat-transfer data were evaluated from temperature time histories measured on a cooled cylindrical model with a cone-shaped nose and with turbulent flow at Mach numbers 3.00, 3.44, 4.08, 4.56, and 5.04. The experimental data were compared with calculated values using a modified Reynold's analogy between skin-friction and heat-transfer. Theoretical skin- friction coefficients were calculated using the method of Van Driest the method of Sommer and Short. The heat-transfer data obtained from the model were found to correlate when the 'T' method of Sommer and Short was used. The increase in turbulent heat-transfer rate with a reduction in wall to freestream temperature ratio was of the same order of magnitude as has been found for the turbulent skin-friction coefficient.
    Keywords: Fluid Mechanics and Heat Transfer
    Type: NASA-TR-R-16
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  • 87
    Publication Date: 2019-08-15
    Description: Thrust, air-handling, and base-pressure characteristics of five ejector configurations were investigated in the Lewis 8-by 6-foot wind tunnel at free-stream Mach numbers from 0 to 2.0 over ranges of primary-jet pressure ratio up to 24 and corrected secondary weight-flow ratio up to 13 percent. The ejector-shroud geometries varied from convergent to divergent. Base pressure ratio and ejector performance were interrelated by means of an exit-momentum parameter. Correlations, to at least a first approximation, with base pressure ratio, of both internal-ejector-flow separation and external-flow separation over the model boattail were shown. Furthermore, it was shown that magnitudes and exact trends in base pressure ratio depended largely, and in a complicated fashion, on ejector geometry and amount of secondary flow. External-stream effects on ejector jet thrust were determined for a typical schedule of jet-engine pressure ratios. With the exception of the ejector having the largest (1.81) shroud-exit-to primary-diameter ratio, there were no stream effects at Mach numbers from 1.5 to 2.0 and variations from quiescent-air thrust data were less than 2.5 percent at the subsonic speed investigated.
    Keywords: Fluid Mechanics and Heat Transfer
    Type: NASA-TM-X-23
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  • 88
    Publication Date: 2019-08-15
    Description: A general relation, empirical in origin, for the mean velocity distribution of both laminar and turbulent boundary layers is proposed. The equation, in general, accurately describes the profiles in both laminar and turbulent flows. The calculation of profiles is based on a prior knowledge of momentum, displacement, and boundary-layer thickness together with free-stream conditions. The form for turbulent layers agrees with the present concepts of similarity of the outer layer. For the inner region or turbulent boundary layers the present relation agrees very closely with experimental measurements even in cases where the logarithmic law of the wall is inadequate. A unique relation between profile form factors and the ratio of displacement thickness to boundary-layer thickness is obtained for turbulent separation. A similar criterion is also obtained for laminar separation. These relations are demonstrated to serve as an accurate criterion for identifying separation in known profiles.
    Keywords: Fluid Mechanics and Heat Transfer
    Type: NASA-MEMO-2-5-59E , E-265
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  • 89
    Publication Date: 2019-08-15
    Description: The results of some experimental and theoretical studies of the interaction of oblique shock waves with laminar boundary layers are presented. Detailed measurements of pressure distribution, shear distribution, and velocity profiles were made during the interaction of oblique shock waves with laminar boundary layers on a flat plate. From these measurements a model was derived to predict the pressure levels characteristic of separation and the length of the separated region.
    Keywords: Fluid Mechanics and Heat Transfer
    Type: NASA-MEMO-2-18-59W
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  • 90
    Publication Date: 2019-08-15
    Description: Reported herein are the results of observations and measurements made in connection with a study of the phenomenon of the development of atmosphere-connected cavities about surface-piercing struts. Conditions for the existence of such ventilated flows which have been derived from the experimental data are presented. In addition, certain broad conclusions pertinent to model testing and full-scale design are reached. Further experimentation to define the inception of ventilation as a function of boundary-layer state or Reynolds number is required.
    Keywords: Fluid Mechanics and Heat Transfer
    Type: NASA-MEMO-2-23-59W , C-476
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  • 91
    Publication Date: 2019-08-15
    Description: The effect of an external boundary layer on the performance of an axisymmetric external-internal-compression inlet was evaluated at Mach numbers of 3.0 and 2.5 and Reynolds numbers from 2.2 to 0.5 x 10(exp 6) per foot. The inlet was tested at locations up to two-thirds of the way into the 1.7- and 9.0-inch boundary layers generated by a flat plate and the tunnel floor, respectively. The inlet could be readily started at all conditions tested, including those where the boundary layer was separated upstream of the inlet by the various shock systems during the restart cycle. Although the inlet performance decreased with increasing immersion into the boundary layer at both Mach numbers, the inlet was more sensitive to boundary-layer ingestion at the design Mach number of 3.0.
    Keywords: Fluid Mechanics and Heat Transfer
    Type: NASA-TM-X-49
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  • 92
    Publication Date: 2019-08-15
    Description: Slender-body theory for subsonic and supersonic flow past bodies of revolution is extended to a second approximation, Methods are developed for handling the difficulties that arise at round ends, Comparison is made with experiment and with other theories for several simple shapes.
    Keywords: Fluid Mechanics and Heat Transfer
    Type: NASA-TR-R-47
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  • 93
    Publication Date: 2019-08-15
    Description: Some 100 numerical computations have been carried out for unyawed bodies of revolution with detached bow waves. The gas is assumed perfect with gamma = 5/3, 7/5, or 1. Free-stream Mach numbers are taken as 1.2, 1.5, 2, 3, 4, 6, 10, and infinity. The results are summarized with emphasis on the sphere and paraboloid.
    Keywords: Fluid Mechanics and Heat Transfer
    Type: NASA-TR-R-1
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  • 94
    Publication Date: 2019-08-15
    Description: A previous analysis of turbulent heat transfer and flow with variable fluid properties in smooth passages is extended to flow over a flat plate at high Mach numbers, and the results are compared with experimental data. Velocity and temperature distributions are calculated for a boundary layer with appreciative effects of frictional heating and external heat transfer. Viscosity and thermal conductivity are assumed to vary as a power or the temperature, while Prandtl number and specific heat are taken as constant. Skin-friction and heat-transfer coefficients are calculated and compared with the incompressible values. The rate of boundary-layer growth is obtained for various Mach numbers.
    Keywords: Fluid Mechanics and Heat Transfer
    Type: NASA-TR-R-17
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  • 95
    Publication Date: 2019-08-15
    Description: Exploratory tests of a circular internal-contraction inlet were made at Mach numbers of 2.00 and 2.35 to determine the effect of a cowl-type boundary-layer control located downstream of the inlet throat. The inlet was designed for a Mach number of 2.5. Tests were also made of the inlet modified to correspond to design Mach numbers of 2.35 and 2.25. Surveys near the minimum area section of the inlet without boundary-layer control indicated maximum averaged pressure recoveries between 0.90 and 0.92 at a free-stream Mach number, M(sub infinity), of 2.35 for the inlets. Farther downstream, after partial subsonic diffusion, a maximum pressure recovery of 0.842 was obtained with the inlet at M(sub infinity) = 2.35. The pressure recovery of the inlet was increased by 0.03 at a Mach number of 2.35 and decreased by 0.02 at a Mach number of 2.00 by the application of cowl-type boundary-layer control. Further investigation with the inlet without bleed demonstrated that an increase of angle of attack from 0 deg to 3 deg reduced the pressure recovery 0.04. The effect of Reynolds number was to increase pressure recovery 0.07 (from 0.785 to 0.855) with an increase in Reynolds number (based on inlet diameter) from 0.79 x 10(exp 6) to 3.19 x 10(exp 6).
    Keywords: Fluid Mechanics and Heat Transfer
    Type: NASA-MEMO-12-31-58A
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  • 96
    Publication Date: 2019-08-15
    Description: A detailed report is given of exact (numerical) solutions of the laminar-boundary-layer equations for the Prandtl number range appropriate to liquid metals (0.003 to 0.03). Consideration is given to the following situations: (1) forced convection over a flat plate for the conditions of uniform wall temperature and uniform wall heat flux, and (2) free convection over an isothermal vertical plate. Tabulations of the new solutions are given in detail. Results are presented for the heat-transfer and shear-stress characteristics; temperature and velocity distributions are also shown. The heat-transfer results are correlated in terms of dimensionless parameters that vary only slightly over the entire liquid-metal range. Previous analytical and experimental work on low Prandtl number boundary layers is surveyed and compared with the new exact solutions.
    Keywords: Fluid Mechanics and Heat Transfer
    Type: NASA-MEMO-2-27-59E
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  • 97
    Publication Date: 2019-08-15
    Description: A hydrodynamic investigation was made in Langley tank no. 1 of a planing surface which was curved longitudinally in the shape of a circular arc with the center of curvature above the model and had a beam of inches and a radius of curvature of 20 beams. The planing surface had length-beam ratio of 9 and an angle of dead rise of 0 deg. Wetted length, resistance, and trimming moment were determined for values of load coefficient C(sub Delta) from -4.2 to 63.9 and values of speed coefficient C(sub V) from 6 to 25. The effects of convexity were to increase the wetted length-beam ratio (for a given lift), to decrease the lift-drag ratio, to move the center of pressure forward, and ta increase the trim for maximum lift-drag ratio as compared with values for a flat surface. The effects were greatest at low trims and large drafts. The maximum negative lift coefficient C(sub L,b) obtainable with a ratio of the radius of curvature to the beam of 20 was -0.02. The effects of camber were greater in magnitude for convexity than for the same amount of concavity.
    Keywords: Fluid Mechanics and Heat Transfer
    Type: NASA-MEMO-1-25-59L , L-159
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  • 98
    Publication Date: 2019-08-15
    Description: Measurements of peak overpressure and Mach stem height were made at four burst heights. Data were obtained with instrumentation capable of directly observing the variation of shock wave movement with time. Good similarity of free air shock peak overpressure with larger scale data was found to exist. The net effect of surface roughness on shock peak overpressures slightly. Surface roughness delayed the Mach stem formation at the greatest charge height and lowered the growth at all burst heights. A similarity parameter was found which approximately correlates the triple point path at different burst heights.
    Keywords: Fluid Mechanics and Heat Transfer
    Type: NASA-TR-R-23
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  • 99
    Publication Date: 2019-08-28
    Description: The profiles and thicknesses of normal shock waves in argon at Mach numbers of 1.335, 1.454, 1.576, and 1-713 were determined experimentally by means of a free-molecule probe whose equilibrium temperature is related by kinetic theory to the local flow properties and their gradients. Comparisons were made between the experimental shock profiles and the theoretical profiles calculated from the Navier-Stokes equations, the Grad 13-moment equations, and the Burnett equations. New, very accurate numerical integrations of the Burnett equations were obtained for this purpose with results quite different from those found by Zoller, to whom the solution of this problem is frequently attributed. The experimental shock profiles were predicted with approximately equal success by the Navier-Stokes and Burnett theories, while the 13-moment method was definitely less satisfactory. A surprising feature of the theoretical results is the relatively small difference in predictions between the Navier-Stokes and Burnett theories in the present range of shock strengths and the contrastingly large difference between predictions of Burnett and the 13-moment theories. It is concluded that the Navier-Stokes equations are correct for weak shocks and that within the present shock strength range the Burnett equations make no improvement which merits the trouble of solving them. For shocks of noticeably greater strength, say with a shock Mach number of more than 2.5, it remains fundamentally doubtful that any of these theories can be correct.
    Keywords: Fluid Mechanics and Heat Transfer
    Type: NASA-MEMO-12-14-58W
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  • 100
    Publication Date: 2019-07-10
    Description: An examination of the effects of compressibility, variable properties, and body forces on fully developed laminar flow has indicated several limitations on such streams. In the absence of a pressure gradient, but presence of a body force (e.g., gravity), an exact fully developed gas flow results. For a liquid this follows also for the case of a constant streamwise pressure gradient. These motions are exact in the sense of a Couette flow. In the liquid case two solutions (not a new result) can occur for the same boundary conditions. An approximate analytic solution was found which agrees closely with machine calculations.In the case of approximately exact flows, it turns out that for large temperature variations across the channel the effects of convection (due to, say, a wall temperature gradient) and frictional heating must be negligible. In such a case the energy and momentum equations are separated, and the solutions are readily obtained. If the temperature variations are small, then both convection effects and frictional heating can consistently be considered. This case becomes the constant-property incompressible case (or quasi-incompressible case for free-convection flows) considered by many authors. Finally there is a brief discussion of cases wherein streamwise variations of all quantities are allowed but only a such form that independent variables are separable. For the case where the streamwise velocity varies inversely as the square root distance along the channel a solution is given.
    Keywords: Fluid Mechanics and Heat Transfer
    Type: NASA-TR-R-34
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