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  • 1
    Keywords: Pharmacology. ; Pharmacy. ; Pharmacology. ; Pharmacy.
    Description / Table of Contents: Introduction -- History of CROs: Including CRO Snapshots and a CRO Genealogy Chart -- The Pharmaceutical Development Process & Testing Requirements -- The Medical Device Development Process & Testing Requirements -- Functions and Types of CROs -- Labs in China and India -- Selection of CROs -- Study Directors and PIs -- Nuts and Bolts of Study Performance SCG/CBS -- Electronic Reporting Requirements (SEND & eCTD) -- Study and Project Monitoring -- Contracting, Pricing, and Cost of Works Performed by CROs -- Consultants and their Role -- Building Relationships: Maximizing your return on Expectations with a CRO -- Common Problems and their Solutions -- Appendices: A Toxicology Labs B Medical Device Labs C Phase I Labs D Analytical Labs E GMP Contract Facilities F Formulation G Dosage Forms H Clinical Testing I Regulatory Services J Forms and Checklists -- K Specialized Services -- L Consultants Known to be In-Practice -- Index. .
    Abstract: This volume provides a complete update of all the materials in prior volumes on the subject (including current directories to testing labs and other support establishments worldwide), while adding substantial new material on the following topics: · The history of CROs, including snapshots of CROs and a genealogy chart making clear where they came from and where they went. · Study directors and principal investigators. · The nuts and bolts of study performance. · Electronic reporting requirements – SEND and eCTD (required for NDA, BLA, ANDA, and IND submissions). · Consultants and their roles. · An expanded examination of common problems and their solutions. This book boasts complete directories to the global universe of operating labs – where they are, how to contact them, and what they do (including special capabilities). Additionally, checklists for qualifying labs and manufacturing facilities – and for auditing studies and projects at such facilities – are included. It is directed at those in industry (specifically directed at those working for companies using CRO services) but will also be of interest to scientists or administrators working in research organizations themselves. In this case, the contents of this new work are essential to the target reader because the work, regulations, and actors (CROs) have evolved and changed at a rapid pace in the 10 years since the earlier volume that the author published. Likewise, the companies using these services have come to all be almost completely dependent on outsourcing. The earlier texts remain the only source of their kind (paper or electronic) on the field and the only noncommercial guide to the global industry and this volume provides a complete update.
    Type of Medium: Online Resource
    Pages: XIII, 519 p. 19 illus., 1 illus. in color. , online resource.
    Edition: 1st ed. 2020.
    ISBN: 9783030430733
    DDC: 615
    Language: English
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  • 2
    Keywords: Geographic information systems. ; Environmental geography. ; Physical geography. ; Environmental management. ; Geographical Information System. ; Integrated Geography. ; Earth System Sciences. ; Environmental Management.
    Description / Table of Contents: Development of Reconfigurable Low-Power Measuring IoT Device for Detecting Common Radioactive Elements for Earth and Space Applications -- RECO-FSCA: Reconfigurable Low-Power Implementation of Fprime-Software for CubeSats Applications -- Autonomous Payload Imaging System for Remote Sensing Applications -- Plasma Space Debris Removal System – NIRCSAT-X -- Heat Energy Storage Module for Thermal Management of Small Satellites In Low Earth Orbit Thermal Conditions.
    Abstract: This book covers various aspects of remote sensing and geographic information systems, from the perspective of earth and environmental sciences. The theme of applications of remote sensing and geographic information systems for the purposes of sustainable development highlights the innovative usage of space imaged spectral data in soil characterization. This book merges the selected contributions to the First International Conference of Remote Sensing and Space Sciences Applications (Egypt 2022) aiming to promote the latest findings on the development of Space Technologies and Applications.
    Type of Medium: Online Resource
    Pages: XIV, 441 p. 168 illus., 157 illus. in color. , online resource.
    Edition: 1st ed. 2023.
    ISBN: 9783031404474
    Series Statement: Springer Proceedings in Earth and Environmental Sciences,
    DDC: 910.285
    Language: English
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  • 3
    Keywords: Geophysics. ; Geotechnical engineering. ; Archaeology. ; Geophysics. ; Geotechnical Engineering and Applied Earth Sciences. ; Archaeology.
    Description / Table of Contents: Landslide mitigation measures for the conservation of the archaeological site of Orongo (Easter Island-Chile) -- Conservation polices and mitigation measures for the Akapana Pyramid in the Tiwanaku archaeological site (Bolivia) -- Multiscale analysis of geohazards affecting the Alhambra (Spain) Cultural Heritage -- Rock mechanic characterization and 3D Kinematic analysis of Katsky pillar (Georgia) -- Petrological study on the Roman mortars from Kom El-Dikka Archaeological Site (Alexandria, Egypt) -- Electrochemical desalination of salt infected brick masonry applying a double electrode system -- Keynote: Investigation and preservation of historic foundations -- Keynote: Preventive Conservation of the Central Tower of Bayon Temple under Global Warming: Case Study in Soil Filled Foundation and Character Defining Elements of Authenticity of Foundation in Angkor, Cambodia -- Slope instability induced by climate changes on the UNESCO Etruscan necropolis (Tarquinia, Central Italy) -- Keynote: NRIAG effort to mitigate natural and geotechnical risk in cultural heritage site -- The Potential and Limitations of Electrical Resistivity and Magnetic Methods for Characterizing Highly Terrainous Archaeological Site: A Case Study At Tell Dibgou, Egypt -- The implementation of shallow geophysical survey for detection of some buried archaeological structures in Aswan city, Egypt -- The use of InfraRed Thermography (IRT) for the protection and conservation of rupestrian CH sites affected by slope instabilities -- Ground Penetrating Radar for investigating painted walls and floors of ancient buildings -- Frozen mounds of Altay mounting geophysical studies -- Keynote: Developments in the digital documentation of tangible Cultural heritage. Advances in data acquisition, processing methods and curating -- Usage of laser scanning system to document the historical heritage of Beet Al Qadi, Cairo -- An HBIM Holistic Approach for Rehabilitation of Heritage Buildings -- Keynote: Geophysics' role in investigating and mitigating groundwater hazards on archaeological sites: Case studies from "Sphinx -Giza, Kom Ombo Temple-Aswan and Hawara Pyramid-Fayoum -- Hydrogelogical hazard assessment and monitoring of Maya Devi Temple World Heritage sites in Lumbini (Nepal): the Birthplace of the Lord Buddha -- Water Infiltration and Waterproofing of Susan-ri Tomb (North Korea) -- Monitoring cultural heritage sites affected by geohazards -- Innovative structural monitoring as tool of preservation and valorisation of monumental architectures: the case of Neptune Temple in Paestum IT -- Structure Stability Analyses of Chapels Dedicated to Wives of Amun Using Non-Contact Techniques, Madinet Habu temple – Luxor – Egypt -- Integrated characterization of Apulian hypogean cultural heritage (Italy) -- Geological control on the evolution of stability of Theban tombs at Sheikh ‘Abd el-Qurna, Luxor, Egypt -- Keynote: Archeoseismology and the Impact of Large Earthquakes on Cultural Heritage -- Integrated Geoscience Investigations in Hittite Imperial Sites Affected by Earthquakes -- Multi-Scenario Physics-Based Seismic Hazard Assessment of Cultural Heritage Sites -- State of buildings and related damage after the earthquake of 1856 in Jijel (Algeria). Considerations for seismic hazard assessment in Jijel and Skikda (Algeria) -- Seismic hazard assessment of a cultural heritage minaret in Cairo -- Keynote: Analysis, integration and interpretation of Big Earth data in the Copernicus Era for the documentation, monitoring and preservation of natural and cultural heritage -- The potential of satellite interferometry for geohazard assessment in cultural heritage sites -- Instability processes and SAR data analysis in the Pompeii archeological park -- Remote Sensing applications for Cultural Heritage Sites Sustainability: case studies form Egypt -- Rome walls satellite monitoring and protection by prothego methodology -- The project of Parco Archeologico del Colosseo and the Italian network of archaeological parks: from satellite monitoring to conservation and preventive maintenance policies -- Adaptation, traditions and conservation: The Case of the Asante Traditional Buildings World Heritage Site in Ghana -- Management of Cultural Assets in Sudan from the Perspective of Sustainable Development Goals -- Improvement the State of Conservation of the Georgian Rock-cut Heritage through the Multidisciplinary Approach -- The Aswan declaration.
    Abstract: This book presents up-to-date geoscience technologies for heritage investigations and conservation, covering various sub-disciplines of geophysics, geodesy, 3D laser scanning technology, hydrogeology, and rock mechanics applied to the exploration of new heritage sites, mapping and visualization, as well as hazard mitigation. The current shift toward interdisciplinary ways of thinking highlights the added value of merging arts with sciences and other disciplines for better management and preservation of cultural heritage. Featuring advanced scientific investigations in 40 case studies around the globe, the book demonstrates how a better understanding of natural processes coupled with conservation approaches, mainly based on sustainable practices such as the use of traditional knowledge in recovery techniques and building local capacities, can ensure effective conservation.
    Type of Medium: Online Resource
    Pages: XI, 734 p. 565 illus., 538 illus. in color. , online resource.
    Edition: 1st ed. 2023.
    ISBN: 9783031138102
    Series Statement: Springer Geology,
    DDC: 550
    Language: English
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  • 4
    Keywords: Sustainability. ; Water. ; Hydrology. ; Mining engineering. ; Sustainability. ; Water. ; Mining and Exploration.
    Description / Table of Contents: Chapter 1. Introduction -- Chapter 2. Materials Used -- Chapter 3. Methodology -- Chapter 4. Results and Discussion. .
    Abstract: This book provides accurate and integrated information about land resources especially with the accelerated progress of information technology to help Egypt and similar countries to achieve the country sustainable development goals in the field of agriculture and natural resources. The Egyptian National sustainable development plans mainly aim to conserve the arable lands in the Nile Delta and the Nile Valley, in addition to the oases and desert fringes. Moreover, increasing land productivity is a vital national goal for filling the food gap. Consequently, providing accurate and integrated information about land natural resources using the recent technologies such as satellite data/images and geoinformatics techniques. Such information would be a base for planning, decision making and research needs all over the world due to the importance of Egypt as the biggest and leading country in the MENA regions. The book provides land natural resources database as a platform, upon which additional thematic information can be added in the future to serve multi approached sustainable development. The book highlights the usage of digital information in monitoring urban planning and encroachment, in addition to soil and land capability classification. Moreover, networks of irrigation/drainages, railways, and utilities are added for a wide management range. Various available information systems were employed to initiate the targeted land resources database (e.g., ArcGIS, ERDAS IMAGINE and ENVI). Data of previous soil survey projects were the basis for the created digital database including High Dam Soil Survey, Soil map of Egypt and Land Master Plane. The Digital Elevation Model (DEM) was elaborated using SRTM space images, in addition to spot heights and contour lines derived from the topographic maps (scale 1:50,000) produced by the Egyptian Survey Authority (ESA). The resulted thematic layers were incorporated in the created GIS land resources database. The book is a unique and a great source of information and knowledge for all researchers around the globe particularly for MENA regions. Researchers, graduate students, the policy planners and decision making will find this book very useful for them. are most people who could benefit from the book. We believe the book will be an added value to the existing information and knowledge.
    Type of Medium: Online Resource
    Pages: XV, 654 p. 586 illus., 584 illus. in color. , online resource.
    Edition: 1st ed. 2023.
    ISBN: 9783031371677
    Series Statement: Deltas of the World,
    DDC: 304.2
    Language: English
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  • 5
    Call number: S 90.0066(150)
    In: Geologisches Jahrbuch
    Type of Medium: Series available for loan
    Pages: 13 S.
    Series Statement: Geologisches Jahrbuch : Reihe A 150
    Language: German
    Location: Lower compact magazine
    Branch Library: GFZ Library
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  • 6
    Call number: IASS 20.95394
    Description / Table of Contents: Though it's many miles away from tiny Denmark, Greenland is administered as an autonomous country within the Danish Realm. It's a relationship that at first glance appears unusual, and, as Ulrik Pram Gad shows, that relationship is quietly predicated on a general assumption that Greenland is on a path toward eventual independence. In both nations, he shows, discussion of Greenland invokes the idea of the "community of the realm" while recognizing Greenland's continuing reliance on aid as it moves toward independence. As climate change is beginning to open up new areas of Greenland to potentially profitable resource extraction, Greenland is increasingly imagining that sources other than Denmark can provide the assistance needed. Throw in the EU, which facilitates "sovereignty games" played to allow Greenland a surprising measure of independent agency, and the complexity of the overall situation becomes quite clear. Gad explores the issue through four lenses: discourse analysis to determine the core concepts of Danish and Greenlandic identity; a reading of political debates as identity politics; interviews with key actors; and analysis of legal texts as a frozen outcome of various sovereignty games. The book concludes with a series of scenarios for the slow motion decolonization of Greenland
    Type of Medium: Monograph available for loan
    Pages: 150 Seiten , Illustrationen
    ISBN: 9788763545020 , 8763545020
    Series Statement: Monographs on Greenland 353
    Language: English
    Branch Library: RIFS Library
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  • 7
    Call number: IASS 21.94320
    Description / Table of Contents: Introduction sustainability as a political concept in the Arctic / Jeppe Strandsbjerg, Marc Jacobsen & Ulrik Pram Gad -- The sustainability of what? Stocks, communities, the public purse? / Rikke Becker-Jacobsen -- Sustainability understandings of Arctic shipping / Kathrin Keil -- Digging sustainability scaling and sectoring of benefits and responsibilities in Greenland and Nunavut mining discourses / Marc Jacobsen -- "Without seals, there are no Greenlanders" Colonial and postcolonial narratives of sustainability and Inuit seal hunting / Naja Graugaard -- Scaling sustainability in the Arctic / Frank Sejersen -- Same word, same idea? Sustainable development talk and the Russian Arctic / Elana Wilson Rowe -- The right to sustainable development and Greenland's lack of a climate policy / Lill Bjørst -- Building a blue economy in the Arctic Ocean : sustaining the sea, or sustaining the state? / Berit Kristoffersen & Philip Steinberg -- Saving the Arctic : green peace or oil riot? / Hannes Gerhardt, Berit Kristoffersen and Kirsti Stuvøy -- Sustaining the Arctic nation-state : the case of Norway, Iceland, and Canada / Ingrid Medby -- 'How we use our nature." Sustainability and indigeneity in Greenlandic discourse / Kirsten Thisted -- Sustaining Denmark - sustaining Greenland / Johanne Bruun -- A new path in the last frontier state? Transforming energy geogragrahies of agency, sovereignty, and sustainability in Alaska / Victoria Hermann -- Geo-assembling narratives of sustainability in Greenland / Klaus Dodds & Mark Nuttall -- Conclusion : sustainability reconfiguring time, space and identity / Ulrik Pram Gad & Jeppe Strandsbjerg
    Description / Table of Contents: "The Politics of Sustainability in the Arctic argues that sustainability is a political concept because it defines and shapes competing visions of the future. In current Arctic affairs, prominent stakeholders agree that development needs to be sustainable, but there is no agreement over what it is that needs to be sustained. In original conservationist discourse, the environment was the sole referent object of sustainability, however, as sustainability discourses expand, the concept is linked to an increasing number of referent objects, such as, society, economy, culture and identity. This book sets out a theoretical framework for understanding and analysing sustainability as a political concept, and provides a comprehensive empirical investigation of Arctic sustainability discourses. Presenting a range of case studies from Greenland, Norway, Canada, Russia, Iceland and Alaska, the essays in this volume analyse the concept of sustainability and how actors are employing and contesting this concept in specific regions within the Arctic. In doing so, the book demonstrates how sustainability is being given new meanings in the postcolonial Arctic and what the political implications are for postcoloniality, nature, and development more broadly. Beyond those interested in the Arctic, this book will also be of great value to students and scholars of sustainability, sustainable development, and identity and environmental politics"--
    Type of Medium: Monograph available for loan
    Pages: xiii, 261 pages , illustrations , 25 cm
    ISBN: 9781138491830 , 9780367500603 , 9781351031981 , 9781351031981
    Series Statement: Routledge studies in sustainability
    Language: English
    Branch Library: RIFS Library
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  • 8
    Publication Date: 2020-09-21
    Description: The Cancer Genome Atlas (TCGA) and International Cancer Genome Consortium (ICGC) curated consensus somatic mutation calls using whole exome sequencing (WES) and whole genome sequencing (WGS), respectively. Here, as part of the ICGC/TCGA Pan-Cancer Analysis of Whole Genomes (PCAWG) Consortium, which aggregated whole genome sequencing data from 2,658 cancers across 38 tumour types, we compare WES and WGS side-by-side from 746 TCGA samples, finding that ~80% of mutations overlap in covered exonic regions. We estimate that low variant allele fraction (VAF 
    Electronic ISSN: 2041-1723
    Topics: Biology , Chemistry and Pharmacology , Natural Sciences in General , Physics
    Published by Springer Nature
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  • 9
  • 10
    Publication Date: 2015-02-01
    Print ISSN: 0960-1481
    Electronic ISSN: 1879-0682
    Topics: Energy, Environment Protection, Nuclear Power Engineering
    Published by Elsevier
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