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  • 1
    Electronic Resource
    Electronic Resource
    A resin-based method for the preparation of molecular nitrogen for ^1^5N analysis from urinary and plasma components
    Amsterdam : Elsevier
    Analytical Biochemistry 123 (1982), S. 249-254 
    Details
    ISSN: 0003-2697
    Source: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
    Topics: Biology , Chemistry and Pharmacology
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1016/0003-2697(82)90442-0
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  • 2
    Electronic Resource
    Electronic Resource
    Recent advances in the use of labelled amino-acids to quantitate protein metabolism in man
    Amsterdam : Elsevier
    International Journal of Radiation Applications & Instrumentation. Part 39 (1988), S. 523 
    Details
    ISSN: 0883-2889
    Source: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
    Topics: Energy, Environment Protection, Nuclear Power Engineering
    Type of Medium: Electronic Resource
    URL: http://linkinghub.elsevier.com/retrieve/pii/0883-2889(88)90229-8
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  • 3
    Electronic Resource
    Electronic Resource
    Herbicides and Selective Phytotoxicity (1951)
    Palo Alto, Calif. : Annual Reviews
    Annual Review of Plant Physiology 2 (1951), S. 199-230 
    Details
    ISSN: 0066-4294
    Source: Annual Reviews Electronic Back Volume Collection 1932-2001ff
    Topics: Biology
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1146/annurev.pp.02.060151.001215
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  • 4
    Electronic Resource
    Electronic Resource
    Time resolved photoluminescence studies in a reverse biased quantum well laser structure (1992)
    Woodbury, NY : American Institute of Physics (AIP)
    Applied Physics Letters 61 (1992), S. 2497-2499 
    Details
    ISSN: 1077-3118
    Source: AIP Digital Archive
    Topics: Physics
    Notes: We report measurements of photoluminescence decay time in a reverse biased GaAs/AlGaAs graded index separate confined heterostructure single quantum well (GRINSCH-SQW) laser, as a function of bias voltage at temperatures of 20, 70, and 150 K. For certain bias voltages and temperatures, we observe extremely fast escape times of optically generated carriers. We propose a simple model based on photogenerated electron recombination in the quantum well, and escape via direct tunneling out of the lower bound electronic level, thermally assisted tunneling out of the upper weakly bound state, or thermionic emission over the barrier. We have performed a theoretical calculation of each of these processes and show that the data agrees well with the direct and thermally assisted tunneling times and that the thermionic emission term underestimates the times.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1063/1.108160
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  • 5
    Electronic Resource
    Electronic Resource
    Geodetic Measurements by Radar (1949)
    [s.l.] : Nature Publishing Group
    Nature 164 (1949), S. 1005-1006 
    Details
    ISSN: 1476-4687
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Chemistry and Pharmacology , Medicine , Natural Sciences in General , Physics
    Notes: [Auszug] HART1 has referred to the potential uses of radar in geodesy and photogrammetry. The War Office has now granted permission to publish details of geodetic observations made in Italy by radar during May–June 1945. The general principle of these observations was that an aircraft, a ...
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1038/1641005a0
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  • 6
    Electronic Resource
    Electronic Resource
    Effect of interdiffusion and impurities on thin film CdTe/CdS photovoltaic junctions (2000)
    Springer
    Journal of materials science 11 (2000), S. 525-530 
    Details
    ISSN: 1573-482X
    Source: Springer Online Journal Archives 1860-2000
    Topics: Electrical Engineering, Measurement and Control Technology , Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics
    Notes: Abstract We have used low temperature photoluminescence (PL) to study thin film CdTe/CdS solar cell structures. The devices were produced by close space sublimation (CSS) and have undergone a post-growth treatment, a vital step in increasing device efficiency. The treatment consisted of evaporating a thin layer of CdCl2 onto the back CdTe surface and heat treating in air at 400 °C for between 10 and 120 min. This produced a range of device efficiencies from 2% to 9%. The efficiency improvements are the result of a complex interaction between the CdCl2, impurities and sulfur interdiffusion. The structures were prepared for PL by a chemical bevel etching technique which allows the luminescence emission to be studied as a function of depth throughout the sample. The main features in the PL spectra have been identified as being due to the Cl-A center and the Te-dislocation-related Y luminescence band. Using PL we have quantified the S diffusion into the CdTe which has a maximum of 20% at the interface in the most efficient samples. We have also obtained the profiles of recombination and non-radiative recombination centers in the device. We observe correlations between impurity centers and device efficiency which can help explain the effects of the CdCl2 treatment on the optoelectronic properties of the CdTe/CdS junction.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1023/A:1026565632569
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  • 7
    Electronic Resource
    Electronic Resource
    Effects of Duchenne muscular dystrophy on muscle protein synthesis (1982)
    [s.l.] : Nature Publishing Group
    Nature 296 (1982), S. 165-167 
    Details
    ISSN: 1476-4687
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Chemistry and Pharmacology , Medicine , Natural Sciences in General , Physics
    Notes: [Auszug] We studied seven normal fed adult men aged 22-65 yr and five boys with Duchenne muscular dystrophy, aged 12-1 Syr. Three of the patients were wheelchair bound and the two youngest were on the verge of becoming so. Investigations of these subjects using radioactive isotopes would not have been ...
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1038/296165a0
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  • 8
    Electronic Resource
    Electronic Resource
    Molecular analysis of eight mutations in FBN1 (1999)
    Springer
    Human genetics 〈Berlin〉 105 (1999), S. 587-597 
    Details
    ISSN: 1432-1203
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Notes: Abstract. Mutations in the gene encoding extracellular glycoprotein fibrillin-1 (FBN1) cause Marfan syndrome (MFS) and other related connective tissue disorders. In this study, eight mutations have been detected in MFS patients by heteroduplex analysis. These comprise two missense mutations, C1835Y and C2258Y in calcium-binding epidermal growth factor-like domains, two nonsense mutations, R1541X and R2394X in transforming growth factor β1-binding protein-like domains, one splice site mutation, which has been detected previously, and three small insertions or deletions resulting in a frameshift. Fibroblast cells have been established from seven of the MFS patients and the biochemical effects of the mutations on fibrillin-1 synthesis and secretion assessed by pulse-chase analysis. Each cysteine mutation resulted in the delayed secretion of fibrillin-1 and both nonsense and frameshift mutations caused reduced levels of synthesis and/or deposition of fibrillin-1. Indirect immunofluorescence and rotary shadowing electron microscopy analysis of fibrillin microfibrils revealed no major differences between normal and patient samples. We discuss the relative merits of the biochemical techniques used in this study.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/s004399900190
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  • 9
    Electronic Resource
    Electronic Resource
    Practical considerations in the use of stable isotope labelled compounds as tracers in clinical studies (1989)
    Chichester : Wiley-Blackwell
    Biological Mass Spectrometry 18 (1989), S. 321-327 
    Details
    ISSN: 0887-6134
    Keywords: Chemistry ; Analytical Chemistry and Spectroscopy
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology
    Notes: Increasingly widespread usage of stable isotope tracers to aid clinical diagnosis and support basic research has stemmed from both advances in mass spectrometry and the availability of competitively priced labelled compounds. Stable isotopes have been used generally to investigate normal and abnormal metabolic pathways, to estimate energy expenditure and body composition and to quantitate substrate flux and oxidation rates. Despite the fact that the underlying principles relating to the use of stable isotopes for in vivo studies are straightforward, careful consideration must be given to all aspects of human studies. This review highlights some of these, including choice of label and tracer molecule, mode of tracer administration and sampling site, analytical instrumentation, interpretation of data and ethical constraints.
    Additional Material: 1 Ill.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/bms.1200180507
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  • 10
    Electronic Resource
    Electronic Resource
    Precise measurement of total body water using trace quantities of deuterium oxide (1977)
    Chichester : Wiley-Blackwell
    Biological Mass Spectrometry 4 (1977), S. 82-87 
    Details
    ISSN: 1052-9306
    Keywords: Chemistry ; Analytical Chemistry and Spectroscopy
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology
    Notes: This study was undertaken to investigate the possibility of measuring total body water in human subjects to better than ±0.5%. Accurate serial estimates of total body water were required to complement densitometric and anthropometric measurements used to monitor body compositional changes in obese patients undergoing dietary or surgical weight reduction therapy. The method required the oral administration of 1-2 g of deuterium oxide and the analysis of pre-dose and respective equilibrated samples of urine, plasma or saliva. The sample size required for analysis was 5 μl and the conversion of gaseous phase was accomplished using a uranium reduction furnace. Isotopic erichment of samples was measured using a mass spectrometer incorporating several features designed to cope with problems inherent in H2/H2H isootopic analysis. Reproducibility of sample preparation and accuracy of the mass spectrometer were tested using international standards and shown to give an overall sensitivity of 2 parts in 107 for the determination of deuterium in H2O/H2HO mixtures. This precision has enabled us to demonstrate that isotopic fractionation of deuterium with respect to hydrogen occurs within the body and expands the potential use of this isotope for quantitative biochemical studies in the human subject.
    Additional Material: 1 Ill.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/bms.1200040205
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