Publication Date:
2011-07-19
Description:
Fourteen sesquiterpenoids with an eudesmane C-atom skeleton, including four new ones, (1 β ,5 α ,7 β ,8 β ,11 β )-5-hydroperoxy-1-hydroxyeudesm-4(15)-eno-12,8-lactone ( 1 ), (1 β ,5 α ,7 β ,8 β )-8-(acetyloxy)-5-hydroperoxy-1-hydroxycostic acid methyl ester ( 12 ), and a mixture of (1 β ,3 β ,4 β ,7 β ,8 β )-1,3-dihydroxyeudesma-5,11(13)-dieno-12,8-lactone ( 7 ) and (1 β ,3 β ,4 β ,7 β ,8 β ,11 β )-1,3-dihydroxyeudesm-5-eno-12,8-lactone ( 8 ), were isolated from the aerial parts of Inula japonica (Asteraceae). Their structures were determined by extensive spectroscopic methods, and those of 7 and 12 confirmed by means of single-crystal X-ray diffraction analysis.
Print ISSN:
0018-019X
Electronic ISSN:
1522-2675
Topics:
Chemistry and Pharmacology
Permalink