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  • 1
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    Occurrence of the Isopod Archaeoniscus coreaensis New Species from the Lower Cretaceous Jinju Formation, Korea (2012)
    Paleontological Society
    Details
    Publication Date: 2012-07-01
    Description: A bstract The fossil isopod crustacean genus Archaeoniscus has been known to occur in England, France and Germany during the Upper Jurassic, and in Mexico and Egypt during the Lower Cretaceous. The morphology of this genus is unique in having dorsoventrally compressed body, the cephalon set deeply into the first pereionite, pleon as wide as pereion, and a broad semicircular pleotelson. These features have resulted in placing the classification of the genus in the monotypic family Archaeoniscidae. However, due to the lack of detailed morphological data, suprafamilial classification of this genus has remained unclear, as well as its ecology and lifestyle. Here we report Archaeoniscus coreaensis n. sp. from the Jinju Formation, Gyeongsang Basin, Korea. The occurrence of Archaeoniscus in the East Asia implies that the genus may have had a worldwide distribution. The Gyeongsang Basin was a Cretaceous backarc basin, which consists of exclusively non-marine sedimentary sequences. The occurrence of this genus, therefore, indicates that Archaeoniscus successfully adapted to a freshwater ecosystem as well. Detailed anatomy including antennulae, antennae, pereiopods, and uropods was observed from well-preserved multiple specimens, which allows better understanding of the morphology of Archaeoniscus . The axial structure in the posterior part of the body, which was previously interpreted as a unique brood pouch characterizing the family, turned out to be a remnant of the hindgut. Females of all isopods and most of the members of the superorder Peracarida have a thoracic ventral brood pouch, modified from the thoracic coxal endites. Based on the morphology of the largely unmodified ambulatory pereiopods of A. coreaensis , the possibility of Archaeoniscus being ectoparasitic is discounted. Instead, the flattened body and the form of limbs of A. coreaensis would have been suitable for a benthic lifestyle.
    Print ISSN: 0022-3360
    Electronic ISSN: 1937-2337
    Topics: Geosciences
    Published by Paleontological Society
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  • 2
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    Patient-specific induced pluripotent stem-cell-derived models of LEOPARD syndrome (2010)
    Nature Publishing Group (NPG)
    Details
    Publication Date: 2010-06-11
    Description: The generation of reprogrammed induced pluripotent stem cells (iPSCs) from patients with defined genetic disorders holds the promise of increased understanding of the aetiologies of complex diseases and may also facilitate the development of novel therapeutic interventions. We have generated iPSCs from patients with LEOPARD syndrome (an acronym formed from its main features; that is, lentigines, electrocardiographic abnormalities, ocular hypertelorism, pulmonary valve stenosis, abnormal genitalia, retardation of growth and deafness), an autosomal-dominant developmental disorder belonging to a relatively prevalent class of inherited RAS-mitogen-activated protein kinase signalling diseases, which also includes Noonan syndrome, with pleomorphic effects on several tissues and organ systems. The patient-derived cells have a mutation in the PTPN11 gene, which encodes the SHP2 phosphatase. The iPSCs have been extensively characterized and produce multiple differentiated cell lineages. A major disease phenotype in patients with LEOPARD syndrome is hypertrophic cardiomyopathy. We show that in vitro-derived cardiomyocytes from LEOPARD syndrome iPSCs are larger, have a higher degree of sarcomeric organization and preferential localization of NFATC4 in the nucleus when compared with cardiomyocytes derived from human embryonic stem cells or wild-type iPSCs derived from a healthy brother of one of the LEOPARD syndrome patients. These features correlate with a potential hypertrophic state. We also provide molecular insights into signalling pathways that may promote the disease phenotype.〈br /〉〈br /〉〈a href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2885001/" target="_blank"〉〈img src="https://static.pubmed.gov/portal/portal3rc.fcgi/4089621/img/3977009" border="0"〉〈/a〉   〈a href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2885001/" target="_blank"〉This paper as free author manuscript - peer-reviewed and accepted for publication〈/a〉〈br /〉〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Carvajal-Vergara, Xonia -- Sevilla, Ana -- D'Souza, Sunita L -- Ang, Yen-Sin -- Schaniel, Christoph -- Lee, Dung-Fang -- Yang, Lei -- Kaplan, Aaron D -- Adler, Eric D -- Rozov, Roye -- Ge, Yongchao -- Cohen, Ninette -- Edelmann, Lisa J -- Chang, Betty -- Waghray, Avinash -- Su, Jie -- Pardo, Sherly -- Lichtenbelt, Klaske D -- Tartaglia, Marco -- Gelb, Bruce D -- Lemischka, Ihor R -- 5R01GM078465/GM/NIGMS NIH HHS/ -- R01 GM078465/GM/NIGMS NIH HHS/ -- R01 GM078465-03/GM/NIGMS NIH HHS/ -- England -- Nature. 2010 Jun 10;465(7299):808-12. doi: 10.1038/nature09005.〈br /〉〈span class="detail_caption"〉Author address: 〈/span〉Department of Gene and Cell Medicine, Black Family Stem Cell Institute, Mount Sinai School of Medicine, New York, New York 10029, USA. xcarvajal@gmail.com〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/20535210" target="_blank"〉PubMed〈/a〉
    Keywords: Adult ; Cell Differentiation ; Cell Line ; Cell Lineage ; Cells, Cultured ; Embryonic Stem Cells/metabolism ; Enzyme Activation ; Female ; Fibroblasts/metabolism/pathology ; Gene Expression Profiling ; Homeodomain Proteins/genetics ; Humans ; Induced Pluripotent Stem Cells/enzymology/metabolism/*pathology ; LEOPARD Syndrome/drug therapy/metabolism/*pathology ; Male ; Mitogen-Activated Protein Kinases/metabolism ; *Models, Biological ; Myocytes, Cardiac/metabolism/pathology ; NFATC Transcription Factors/genetics/metabolism ; Octamer Transcription Factor-3/genetics ; Phosphoproteins/analysis ; Polymerase Chain Reaction ; *Precision Medicine ; Protein Tyrosine Phosphatase, Non-Receptor Type 11/genetics/metabolism ; SOXB1 Transcription Factors/genetics
    Print ISSN: 0028-0836
    Electronic ISSN: 1476-4687
    Topics: Biology , Chemistry and Pharmacology , Medicine , Natural Sciences in General , Physics
    Published by Nature Publishing Group (NPG)
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  • 3
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    High-performance high-TC superconducting wires (2006)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 2006-04-01
    Description: We demonstrated short segments of a superconducting wire that meets or exceeds performance requirements for many large-scale applications of high-temperature superconducting materials, especially those requiring a high supercurrent and/or a high engineering critical current density in applied magnetic fields. The performance requirements for these varied applications were met in 3-micrometer-thick YBa2Cu3O(7-delta) films epitaxially grown via pulsed laser ablation on rolling assisted biaxially textured substrates. Enhancements of the critical current in self-field as well as excellent retention of this current in high applied magnetic fields were achieved in the thick films via incorporation of a periodic array of extended columnar defects, composed of self-aligned nanodots of nonsuperconducting material extending through the entire thickness of the film. These columnar defects are highly effective in pinning the superconducting vortices or flux lines, thereby resulting in the substantially enhanced performance of this wire.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Kang, S -- Goyal, A -- Li, J -- Gapud, A A -- Martin, P M -- Heatherly, L -- Thompson, J R -- Christen, D K -- List, F A -- Paranthaman, M -- Lee, D F -- New York, N.Y. -- Science. 2006 Mar 31;311(5769):1911-4.〈br /〉〈span class="detail_caption"〉Author address: 〈/span〉Oak Ridge National Laboratory, Oak Ridge, TN 37831, USA.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/16574864" target="_blank"〉PubMed〈/a〉
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
    Published by American Association for the Advancement of Science (AAAS)
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  • 4
    Electronic Resource
    Electronic Resource
    Interference with the Determination of Aldrin and Benzene Hexachloride Residues by Gas Chromatography (1966)
    [s.l.] : Nature Publishing Group
    Nature 211 (1966), S. 521-522 
    Details
    ISSN: 1476-4687
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Chemistry and Pharmacology , Medicine , Natural Sciences in General , Physics
    Notes: [Auszug] Solvents, as purchased, often give this peak, but the contaminant causing the peak can be removed by distillation through a short fractionating column. Distilled solvents and water are recontaminated if kept in contact with polythene, for example, storage bottles and pipework. The contaminant can ...
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1038/211521b0
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  • 5
    Electronic Resource
    Electronic Resource
    Enhancement in thermal shock resistance of melt-textured YBa2Cu3Ox superconductors by hot isostatic pressing (1994)
    Woodbury, NY : American Institute of Physics (AIP)
    Applied Physics Letters 65 (1994), S. 1958-1960 
    Details
    ISSN: 1077-3118
    Source: AIP Digital Archive
    Topics: Physics
    Notes: Thermal shock resistance of melt-textured YBa2Cu3Ox superconductors has been investigated by thermal cycling between 77 and 350 K. The current carrying capability of as-melt-textured specimens is found to drop in three stages by a factor of up to 50% after 60 cycles. To rectify this degradation, a hot isostatic pressing (Hipping) method has been developed to close the microcracks generated during thermal cycling. The critical current (Ic) of specimens that were thermally cycled followed by Hipping is found to increase even above the initial Ic value of its as-melt-textured state. More importantly, Ic of the Hipped specimens is found to be completely insensitive to thermal cycling even after 60 cycles. Indentation measurements revealed that Hipping strengthens the basal plane platelet boundaries in addition to closing the microcracks. © 1994 American Institue of Physics.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1063/1.112829
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  • 6
    Electronic Resource
    Electronic Resource
    Melt texturing of preferentially aligned YBa2Cu3Ox superconductor by a seeded directional solidification method (1994)
    [S.l.] : American Institute of Physics (AIP)
    Journal of Applied Physics 76 (1994), S. 603-605 
    Details
    ISSN: 1089-7550
    Source: AIP Digital Archive
    Topics: Physics
    Notes: Directional solidification has been shown to be capable of producing long lengths of melt-textured YBa2Cu3Ox. In order to maximize the current carrying capability of these superconductors, grain alignment needs to be directed along the sample axis. So far, this preferential grain alignment can only be achieved in samples of small cross-sectional areas. We have developed a seeded directional solidification method which allows the fabrication of long lengths of single-domained YBa2Cu3Ox with large cross-sectional areas and predetermined grain alignment. The current carrying capability of these superconductors is superior to that of the misaligned ones, and the Ic is estimated to be a few thousand amperes for samples of 4×8 mm2 cross-sectional area.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1063/1.357053
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  • 7
    Electronic Resource
    Electronic Resource
    Phase stability for the in situ growth of Nd1+xBa2−xCu3Oy films using pulsed-laser deposition (1999)
    Woodbury, NY : American Institute of Physics (AIP)
    Applied Physics Letters 74 (1999), S. 96-98 
    Details
    ISSN: 1077-3118
    Source: AIP Digital Archive
    Topics: Physics
    Notes: We have determined the stability line in the 1/T−log[P(O2)] phase space for the synthesis of Nd1+xBa2−xCu3Oy (NdBCO) films. A systematic study of Tc, Jc, and ρ(T) dependence on oxygen partial pressure and temperature for the deposition of thin NdBCO films grown by pulsed-laser deposition was performed. The conditions for optimal NdBCO film growth were determined by varying oxygen partial pressure from 0.02 to 400 mTorr, and substrate temperature between 730 and 800 °C. The results show that the best NdBCO films are obtained at oxygen pressures in the range of 0.2–1.2 mTorr, depending on the substrate temperature. This is more than two orders-of-magnitude lower than the correspondent oxygen pressure appropriate for YBa2Cu3O7−δ film growth. © 1999 American Institute of Physics.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1063/1.123162
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  • 8
    Electronic Resource
    Electronic Resource
    Low angle grain boundary transport in YBa2Cu3O7−δ coated conductors (2000)
    Woodbury, NY : American Institute of Physics (AIP)
    Applied Physics Letters 76 (2000), S. 1755-1757 
    Details
    ISSN: 1077-3118
    Source: AIP Digital Archive
    Topics: Physics
    Notes: Second generation, high-temperature superconducting wires are based on buffered, metallic tape substrates of near single crystal texture. Strong alignment of adjacent grains was found to be necessary from previous work that suggested large angle, YBa2Cu3O7−δ [001]-tilt boundaries reduce Jc exponentially with increasing misorientation angle (θ). We pursue the low-θ regime by evaluating single grain boundaries (GB) and biaxially aligned polycrystalline films utilizing both the rolling-assisted biaxially textured substrates and ion-beam assisted deposition coated conductor architectures. Analysis concludes that an exponential dependence on Jc is applicable for θ(approximately-greater-than)4°, where the spacing between the periodic disordered regions along the GB become smaller than a coherence length. © 2000 American Institute of Physics.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1063/1.126157
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  • 9
    Electronic Resource
    Electronic Resource
    Alternating current losses in biaxially textured YBa2Cu3O7−δ films deposited on Ni tapes (1997)
    Woodbury, NY : American Institute of Physics (AIP)
    Applied Physics Letters 71 (1997), S. 2029-2031 
    Details
    ISSN: 1077-3118
    Source: AIP Digital Archive
    Topics: Physics
    Notes: YBa2Cu3O7−δ films grown on rolling-assisted biaxially textured substrates carry critical current densities 105–106 A/cm2 at 77 K and low applied magnetic fields. In the low-field and low-current regime, ac transport current studies show hysteresis energy loss (per cycle and per unit length) roughly the value expected for a superconductor of elliptic cross section. The critical current Ic was deduced from observed dc and dynamic current-voltage relations. The power loss rises sharply as I0 (the maximum current in each cycle) is raised above Ic. In the present configuration, ferromagnetic hysteresis of the Ni substrate contributes little or no loss. © 1997 American Institute of Physics.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1063/1.119777
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  • 10
    Electronic Resource
    Electronic Resource
    High critical current density superconducting tapes by epitaxial deposition of YBa2Cu3Ox thick films on biaxially textured metals (1996)
    Woodbury, NY : American Institute of Physics (AIP)
    Applied Physics Letters 69 (1996), S. 1795-1797 
    Details
    ISSN: 1077-3118
    Source: AIP Digital Archive
    Topics: Physics
    Notes: A method to obtain long lengths of flexible, biaxially oriented substrates with smooth, chemically compatible surfaces for epitaxial growth of high-temperature superconductors is reported. The technique uses well established, industrially scalable, thermomechanical processes to impart a strong biaxial texture to a base metal. This is followed by vapor deposition of epitaxial buffer layers (metal and/or ceramic) to yield chemically compatible surfaces. Epitaxial YBa2Cu3Ox films grown on such substrates have critical current densities exceeding 105 A/cm2 at 77 K in zero field and have field dependencies similar to epitaxial films on single crystal ceramic substrates. Deposited conductors made using this technique offer a potential route for the fabrication of long lengths of high-Jc wire capable of carrying high currents in high magnetic fields and at elevated temperatures. © 1996 American Institute of Physics.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1063/1.117489
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