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  • Artikel  (23)
  • Wiley  (15)
  • American Association for the Advancement of Science (AAAS)  (8)
  • Cell Press
  • 2000-2004  (23)
  • Chemie und Pharmazie  (23)
  • Mathematik
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  • Artikel  (23)
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  • 1
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    Biomedicine. The NASA-NCI collaboration on biomolecular sensors (2001)
    American Association for the Advancement of Science (AAAS)
    Details
    Publikationsdatum: 2001-05-02
    Beschreibung: 〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Goldin, D S -- Dahl, C A -- Olsen, K L -- Ostrach, L H -- Klausner, R D -- New York, N.Y. -- Science. 2001 Apr 20;292(5516):443-4.〈br /〉〈span class="detail_caption"〉Author address: 〈/span〉National Aeronautics and Space Administration (NASA), Washington, DC 20546, USA.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/11330296" target="_blank"〉PubMed〈/a〉
    Schlagwort(e): Biomarkers ; Biomarkers, Tumor ; *Biosensing Techniques ; Miniaturization ; *National Institutes of Health (U.S.) ; *Neoplasms/diagnosis/prevention & control/therapy ; *Research ; *Space Flight ; Spacecraft ; United States ; *United States National Aeronautics and Space Administration
    Print ISSN: 0036-8075
    Digitale ISSN: 1095-9203
    Thema: Biologie , Chemie und Pharmazie , Informatik , Medizin , Allgemeine Naturwissenschaft , Physik
    Publiziert von American Association for the Advancement of Science (AAAS)
    Standort Signatur Erwartet Verfügbarkeit
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  • 2
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    Resistance to an herbivore through engineered cyanogenic glucoside synthesis (2001)
    American Association for the Advancement of Science (AAAS)
    Details
    Publikationsdatum: 2001-07-28
    Beschreibung: The entire pathway for synthesis of the tyrosine-derived cyanogenic glucoside dhurrin has been transferred from Sorghum bicolor to Arabidopsis thaliana. Here, we document that genetically engineered plants are able to synthesize and store large amounts of new natural products. The presence of dhurrin in the transgenic A. thaliana plants confers resistance to the flea beetle Phyllotreta nemorum, which is a natural pest of other members of the crucifer group, demonstrating the potential utility of cyanogenic glucosides in plant defense.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Tattersall, D B -- Bak, S -- Jones, P R -- Olsen, C E -- Nielsen, J K -- Hansen, M L -- Hoj, P B -- Moller, B L -- New York, N.Y. -- Science. 2001 Sep 7;293(5536):1826-8. Epub 2001 Jul 26.〈br /〉〈span class="detail_caption"〉Author address: 〈/span〉Plant Biochemistry Laboratory, Department of Plant Biology, Centre for Molecular Plant Physiology, Department of Chemistry, Royal Veterinary and Agricultural University, 40 Thorvaldsensvej, DK-1871, Frederiksberg C, Denmark.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/11474068" target="_blank"〉PubMed〈/a〉
    Schlagwort(e): Angiosperms/*enzymology/genetics ; Animals ; Arabidopsis/genetics/*metabolism ; Beetles/*physiology ; Chromatography, High Pressure Liquid ; Cytochrome P-450 Enzyme System/genetics/metabolism ; *Eating ; Food Chain ; *Genetic Engineering ; Glucosides/analysis/biosynthesis ; Mixed Function Oxygenases/genetics/metabolism ; Nitriles/analysis/*metabolism ; Pest Control, Biological/*methods ; Plant Leaves/genetics/metabolism ; Plants, Genetically Modified
    Print ISSN: 0036-8075
    Digitale ISSN: 1095-9203
    Thema: Biologie , Chemie und Pharmazie , Informatik , Medizin , Allgemeine Naturwissenschaft , Physik
    Publiziert von American Association for the Advancement of Science (AAAS)
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  • 3
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    Ascent of dinosaurs linked to an iridium anomaly at the Triassic-Jurassic boundary (2002)
    American Association for the Advancement of Science (AAAS)
    Details
    Publikationsdatum: 2002-05-23
    Beschreibung: Analysis of tetrapod footprints and skeletal material from more than 70 localities in eastern North America shows that large theropod dinosaurs appeared less than 10,000 years after the Triassic-Jurassic boundary and less than 30,000 years after the last Triassic taxa, synchronous with a terrestrial mass extinction. This extraordinary turnover is associated with an iridium anomaly (up to 285 parts per trillion, with an average maximum of 141 parts per trillion) and a fern spore spike, suggesting that a bolide impact was the cause. Eastern North American dinosaurian diversity reached a stable maximum less than 100,000 years after the boundary, marking the establishment of dinosaur-dominated communities that prevailed for the next 135 million years.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Olsen, P E -- Kent, D V -- Sues, H-D -- Koeberl, C -- Huber, H -- Montanari, A -- Rainforth, E C -- Fowell, S J -- Szajna, M J -- Hartline, B W -- New York, N.Y. -- Science. 2002 May 17;296(5571):1305-7.〈br /〉〈span class="detail_caption"〉Author address: 〈/span〉Lamont-Doherty Earth Observatory of Columbia University, Palisades, NY 10964, USA.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/12016313" target="_blank"〉PubMed〈/a〉
    Schlagwort(e): Animals ; Biological Evolution ; *Dinosaurs ; *Ecosystem ; Ferns ; *Fossils ; Geologic Sediments/chemistry ; Iridium/*analysis ; Meteoroids ; Minor Planets ; North America ; Spores ; Time
    Print ISSN: 0036-8075
    Digitale ISSN: 1095-9203
    Thema: Biologie , Chemie und Pharmazie , Informatik , Medizin , Allgemeine Naturwissenschaft , Physik
    Publiziert von American Association for the Advancement of Science (AAAS)
    Standort Signatur Erwartet Verfügbarkeit
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  • 4
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    Human chromosome 19 and related regions in mouse: conservative and lineage-specific evolution (2001)
    American Association for the Advancement of Science (AAAS)
    Details
    Publikationsdatum: 2001-07-07
    Beschreibung: To illuminate the function and evolutionary history of both genomes, we sequenced mouse DNA related to human chromosome 19. Comparative sequence alignments yielded confirmatory evidence for hypothetical genes and identified exons, regulatory elements, and candidate genes that were missed by other predictive methods. Chromosome-wide comparisons revealed a difference between single-copy HSA19 genes, which are overwhelmingly conserved in mouse, and genes residing in tandem familial clusters, which differ extensively in number, coding capacity, and organization between the two species. Finally, we sequenced breakpoints of all 15 evolutionary rearrangements, providing a view of the forces that drive chromosome evolution in mammals.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Dehal, P -- Predki, P -- Olsen, A S -- Kobayashi, A -- Folta, P -- Lucas, S -- Land, M -- Terry, A -- Ecale Zhou, C L -- Rash, S -- Zhang, Q -- Gordon, L -- Kim, J -- Elkin, C -- Pollard, M J -- Richardson, P -- Rokhsar, D -- Uberbacher, E -- Hawkins, T -- Branscomb, E -- Stubbs, L -- New York, N.Y. -- Science. 2001 Jul 6;293(5527):104-11.〈br /〉〈span class="detail_caption"〉Author address: 〈/span〉DOE Joint Genome Institute, Walnut Creek, CA 94598, USA.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/11441184" target="_blank"〉PubMed〈/a〉
    Schlagwort(e): Animals ; Chromosome Breakage/genetics ; Chromosomes, Human, Pair 19/*genetics ; Conserved Sequence/*genetics ; Contig Mapping ; DNA, Satellite/genetics ; *Evolution, Molecular ; Exons/genetics ; Expressed Sequence Tags ; Gene Dosage ; Gene Order/genetics ; Genetic Linkage/genetics ; Genome ; Humans ; Long Interspersed Nucleotide Elements/genetics ; Mice ; Multigene Family/genetics ; Open Reading Frames/genetics ; Phylogeny ; Sequence Alignment ; Sequence Analysis, DNA ; Short Interspersed Nucleotide Elements/genetics ; Terminal Repeat Sequences/genetics
    Print ISSN: 0036-8075
    Digitale ISSN: 1095-9203
    Thema: Biologie , Chemie und Pharmazie , Informatik , Medizin , Allgemeine Naturwissenschaft , Physik
    Publiziert von American Association for the Advancement of Science (AAAS)
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  • 5
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    Characterization of a novel coronavirus associated with severe acute respiratory syndrome (2003)
    American Association for the Advancement of Science (AAAS)
    Details
    Publikationsdatum: 2003-05-06
    Beschreibung: In March 2003, a novel coronavirus (SARS-CoV) was discovered in association with cases of severe acute respiratory syndrome (SARS). The sequence of the complete genome of SARS-CoV was determined, and the initial characterization of the viral genome is presented in this report. The genome of SARS-CoV is 29,727 nucleotides in length and has 11 open reading frames, and its genome organization is similar to that of other coronaviruses. Phylogenetic analyses and sequence comparisons showed that SARS-CoV is not closely related to any of the previously characterized coronaviruses.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Rota, Paul A -- Oberste, M Steven -- Monroe, Stephan S -- Nix, W Allan -- Campagnoli, Ray -- Icenogle, Joseph P -- Penaranda, Silvia -- Bankamp, Bettina -- Maher, Kaija -- Chen, Min-Hsin -- Tong, Suxiong -- Tamin, Azaibi -- Lowe, Luis -- Frace, Michael -- DeRisi, Joseph L -- Chen, Qi -- Wang, David -- Erdman, Dean D -- Peret, Teresa C T -- Burns, Cara -- Ksiazek, Thomas G -- Rollin, Pierre E -- Sanchez, Anthony -- Liffick, Stephanie -- Holloway, Brian -- Limor, Josef -- McCaustland, Karen -- Olsen-Rasmussen, Melissa -- Fouchier, Ron -- Gunther, Stephan -- Osterhaus, Albert D M E -- Drosten, Christian -- Pallansch, Mark A -- Anderson, Larry J -- Bellini, William J -- New York, N.Y. -- Science. 2003 May 30;300(5624):1394-9. Epub 2003 May 1.〈br /〉〈span class="detail_caption"〉Author address: 〈/span〉National Center for Infectious Diseases, Centers for Disease Control and Prevention, Atlanta, GA 30333, USA. prota@cdc.gov〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/12730500" target="_blank"〉PubMed〈/a〉
    Schlagwort(e): Amino Acid Sequence ; Conserved Sequence ; Coronavirus/classification/genetics ; DNA, Complementary ; Endopeptidases/chemistry/genetics ; *Genome, Viral ; Humans ; Membrane Glycoproteins/chemistry/genetics ; Molecular Sequence Data ; Nucleocapsid Proteins/chemistry/genetics ; Open Reading Frames ; Phylogeny ; Polyproteins/chemistry/genetics ; RNA Replicase/chemistry/genetics ; RNA, Messenger/genetics/metabolism ; RNA, Viral/*genetics ; Regulatory Sequences, Nucleic Acid ; SARS Virus/chemistry/classification/*genetics/isolation & purification ; Sequence Analysis, DNA ; Severe Acute Respiratory Syndrome/virology ; Spike Glycoprotein, Coronavirus ; Transcription, Genetic ; Viral Envelope Proteins/chemistry/genetics ; Viral Matrix Proteins/chemistry/genetics ; Viral Proteins/chemistry/*genetics
    Print ISSN: 0036-8075
    Digitale ISSN: 1095-9203
    Thema: Biologie , Chemie und Pharmazie , Informatik , Medizin , Allgemeine Naturwissenschaft , Physik
    Publiziert von American Association for the Advancement of Science (AAAS)
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  • 6
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    Lost at sea: where is all the plastic? (2004)
    American Association for the Advancement of Science (AAAS)
    Details
    Publikationsdatum: 2004-05-08
    Beschreibung: 〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Thompson, Richard C -- Olsen, Ylva -- Mitchell, Richard P -- Davis, Anthony -- Rowland, Steven J -- John, Anthony W G -- McGonigle, Daniel -- Russell, Andrea E -- New York, N.Y. -- Science. 2004 May 7;304(5672):838.〈br /〉〈span class="detail_caption"〉Author address: 〈/span〉University of Plymouth, PL4 8AA, UK. rcthompson@plymouth.ac.uk〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/15131299" target="_blank"〉PubMed〈/a〉
    Print ISSN: 0036-8075
    Digitale ISSN: 1095-9203
    Thema: Biologie , Chemie und Pharmazie , Informatik , Medizin , Allgemeine Naturwissenschaft , Physik
    Publiziert von American Association for the Advancement of Science (AAAS)
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  • 7
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    Continental-scale partitioning of fire emissions during the 1997 to 2001 El Nino/La Nina period (2004)
    American Association for the Advancement of Science (AAAS)
    Details
    Publikationsdatum: 2004-01-06
    Beschreibung: During the 1997 to 1998 El Nino, drought conditions triggered widespread increases in fire activity, releasing CH4 and CO2 to the atmosphere. We evaluated the contribution of fires from different continents to variability in these greenhouse gases from 1997 to 2001, using satellite-based estimates of fire activity, biogeochemical modeling, and an inverse analysis of atmospheric CO anomalies. During the 1997 to 1998 El Nino, the fire emissions anomaly was 2.1 +/- 0.8 petagrams of carbon, or 66 +/- 24% of the CO2 growth rate anomaly. The main contributors were Southeast Asia (60%), Central and South America (30%), and boreal regions of Eurasia and North America (10%).〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉van der Werf, Guido R -- Randerson, James T -- Collatz, G James -- Giglio, Louis -- Kasibhatla, Prasad S -- Arellano, Avelino F Jr -- Olsen, Seth C -- Kasischke, Eric S -- New York, N.Y. -- Science. 2004 Jan 2;303(5654):73-6.〈br /〉〈span class="detail_caption"〉Author address: 〈/span〉U.S. Department of Agriculture-Foreign Agricultural Service, National Aeronautics and Space Administration-Goddard Space Flight Center (NASA-GSFC), Code 923, Greenbelt Road, Greenbelt, MD 20771, USA. guido@ltpmailx.gsfc.nasa.gov〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/14704424" target="_blank"〉PubMed〈/a〉
    Print ISSN: 0036-8075
    Digitale ISSN: 1095-9203
    Thema: Biologie , Chemie und Pharmazie , Informatik , Medizin , Allgemeine Naturwissenschaft , Physik
    Publiziert von American Association for the Advancement of Science (AAAS)
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  • 8
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    Darwinian selection on a selfing locus (2004)
    American Association for the Advancement of Science (AAAS)
    Details
    Publikationsdatum: 2004-12-18
    Beschreibung: The shift to self-pollination is one of the most prevalent evolutionary transitions in flowering plants. In the selfing plant Arabidopsis thaliana, pseudogenes at the SCR and SRK self-incompatibility loci are believed to underlie the evolution of self-fertilization. Positive directional selection has driven the evolutionary fixation of pseudogene alleles of SCR, leading to substantially reduced nucleotide variation. Coalescent simulations indicate that this adaptive event may have occurred very recently and is possibly associated with the post-Pleistocene expansion of A. thaliana from glacial refugia. This suggests that ancillary morphological innovations associated with self-pollination can evolve rapidly after the inactivation of the self-incompatibility response.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Shimizu, Kentaro K -- Cork, Jennifer M -- Caicedo, Ana L -- Mays, Charlotte A -- Moore, Richard C -- Olsen, Kenneth M -- Ruzsa, Stephanie -- Coop, Graham -- Bustamante, Carlos D -- Awadalla, Philip -- Purugganan, Michael D -- New York, N.Y. -- Science. 2004 Dec 17;306(5704):2081-4.〈br /〉〈span class="detail_caption"〉Author address: 〈/span〉Department of Genetics, North Carolina State University, Box 7614, Raleigh, NC 27695, USA.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/15604405" target="_blank"〉PubMed〈/a〉
    Schlagwort(e): Alleles ; Arabidopsis/*genetics/*physiology ; Biological Evolution ; Chromosome Mapping ; Climate ; DNA, Intergenic ; *Genes, Plant ; Genetic Variation ; Genome, Plant ; Geography ; Haplotypes ; Likelihood Functions ; Molecular Sequence Data ; Open Reading Frames ; Phylogeny ; Plant Proteins ; Pollen ; Polymorphism, Genetic ; Polymorphism, Single Nucleotide ; Protein Kinases/*genetics/physiology ; *Pseudogenes ; Recombination, Genetic ; *Selection, Genetic ; Time
    Print ISSN: 0036-8075
    Digitale ISSN: 1095-9203
    Thema: Biologie , Chemie und Pharmazie , Informatik , Medizin , Allgemeine Naturwissenschaft , Physik
    Publiziert von American Association for the Advancement of Science (AAAS)
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  • 9
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    Structure of the mitochondrial β-ketoacyl-[acyl carrier protein] synthase fromArabidopsisand its role in fatty acid synthesis (2004)
    Wiley
    Details
    Publikationsdatum: 2004-10-14
    Print ISSN: 0014-5793
    Digitale ISSN: 1873-3468
    Thema: Biologie , Chemie und Pharmazie
    Publiziert von Wiley im Namen von Federation of European Biochemical Societies.
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  • 10
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    Protein kinase CK2 phosphorylates the Fas-associated factor FAF1 in vivo and influences its transport into the nucleus (2003)
    Wiley
    Details
    Publikationsdatum: 2003-05-28
    Print ISSN: 0014-5793
    Digitale ISSN: 1873-3468
    Thema: Biologie , Chemie und Pharmazie
    Publiziert von Wiley im Namen von Federation of European Biochemical Societies.
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