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Actin acetylation in Drosophila tissue culture cells (1981)

Berger, Edward M. ; Cox, Gerard ; Weber, Lee ; [et al.]

Springer

Biochemical genetics 19 (1981), S. 321-331

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ISSN: 1573-4927

Keywords: Drosophila ; embryonic cells ; actin

Source: Springer Online Journal Archives 1860-2000

Topics: Biology , Chemistry and Pharmacology

Notes: Abstract In a permanent cell line derived from Drosophila embryos, cytoplasmic actin is produced as an unstable precursor, which is subsequently converted to a stable form. This conversion results in a reduction in isoelectric point, with no apparent change in molecular weight. The conversion involves an enzymatic acetylation, and results in an insensitivity to aminopeptidase digestion, suggesting N-terminal blockage. Both the acetylated and unacetylated actins can participate in the assembly of F-actin, but with different efficiencies.

Type of Medium: Electronic Resource

URL: http://dx.doi.org/10.1007/BF00504277

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