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  • Nature Publishing Group  (23,614)
  • 1995-1999  (12,082)
  • 1940-1944  (11,532)
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  • 1
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    Nature Publishing Group
    In:  Nature, 384 (6608). p. 421.
    Publication Date: 2021-08-20
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  • 2
    Publication Date: 2021-02-25
    Description: The El Niño/Southern Oscillation (ENSO) phenomenon is the strongest natural interannual climate fluctuation1. ENSO originates in the tropical Pacific Ocean and has large effects on the ecology of the region, but it also influences the entire global climate system and affects the societies and economies of manycountries2. ENSO can be understood as an irregular low-frequency oscillation between a warm (El Niño) and a cold (La Niña) state. The strong El Niños of 1982/1983 and 1997/1998, along with the more frequent occurrences of El Niños during the past few decades, raise the question of whether human-induced 'greenhouse' warming affects, or will affect, ENSO3. Several global climate models have been applied to transient greenhouse-gas-induced warming simulations to address this question4, 6, but the results have been debated owing to the inability of the models to fully simulate ENSO (because of their coarse equatorial resolution)7. Here we present results from a global climate model with sufficient resolution in the tropics to adequately represent the narrow equatorial upwelling and low-frequency waves. When the model is forced by a realistic future scenario of increasing greenhouse-gas concentrations, more frequent El-Niño-like conditions and stronger cold events in the tropical Pacific Ocean result
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  • 3
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    Nature Publishing Group
    In:  Nature, 389 (6652). pp. 683-684.
    Publication Date: 2021-02-15
    Description: Recent captures of two female giant squid ( Architeuthis ) off southern Australia have provided the first record of a mated female specimen of these almost mythical deepsea creatures. We found sperm packages (spermatophores) embedded within the skin of both ventral arms of the larger of the two specimens. It seems that male giant squids may use their muscular elongate penis to ‘inject’ sperm packages under pressure directly into the arms of females.
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  • 4
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    Nature Publishing Group
    In:  Nature, 394 . pp. 266-269.
    Publication Date: 2019-02-27
    Description: In steady state, the export of photosynthetically fixed organic matter to the deep ocean has to be balanced by an upward flux of nutrients into the euphotic zone1. Indirect geochemical estimates2 of the nutrient supply to surface waters have been substantially higher than direct biological and physical measurements3, particularly in subtropical regions. A possible explanation for the apparent discrepancy is that the sampling strategy of the direct measurements has under-represented episodic nutrient injections forced by mesoscale eddy dynamics, whereas geochemical tracer budgets integrate fluxes over longer time and space scales. Here we investigate the eddy-induced nutrient supply by combining two methods potentially capable of delivering synoptic descriptions of the ocean's state on a basin scale. Remotely sensed sea-surface height data from the simultaneous TOPEX/Poseidon and ERS-1 satellite missions are assimilated into a numerical eddy-resolving coupled ecosystem–circulation model of the North Atlantic Ocean. Our results indicate that mesoscale eddy activity accounts for about one-third of the total flux of nitrate into the euphotic zone (taken to represent new production) in the subtropics and at mid-latitudes. This contribution is not sufficient to maintain the observed primary production in parts of the subtropical gyre, where alternative routes of nitrogen supply will have to be considered.
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  • 5
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    Nature Publishing Group
    In:  Nature, 376 (6538). pp. 301-302.
    Publication Date: 2018-08-15
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  • 6
    Publication Date: 2018-01-09
    Description: The nitrogen-isotope record preserved in Southern Ocean sediments, along with several geochemical tracers for the settling fluxes of biogenic matter, reveals patterns of past nutrient supply to phytoplankton and surface-water stratification in this oceanic region. Areal averaging of these spatial patterns indicates that reduction of the CO2 'leak' from ocean to atmosphere by increased surface-water stratification south of the Polar Front made a greater contribution to the lowering of atmospheric CO2 concentration during the Last Glacial Maximum than did the increased export of organic carbon from surface to deep waters occurring further north.
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  • 7
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    Nature Publishing Group
    In:  Nature, 374 (6520). p. 314.
    Publication Date: 2017-07-06
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  • 8
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    Nature Publishing Group
    In:  Nature, 377 (6545). p. 107.
    Publication Date: 2017-07-04
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  • 9
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    Nature Publishing Group
    In:  Nature, 387 . pp. 31-32.
    Publication Date: 2017-02-28
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  • 10
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    Nature Publishing Group
    In:  Nature, 402 . pp. 366-367.
    Publication Date: 2017-02-28
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  • 11
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    In:  Nature, 397 . pp. 243-246.
    Publication Date: 2017-02-28
    Description: The overflow and descent of cold dense water from the Denmark Strait sill-a submarine passage between Greenland and Iceland-is a principal means by which the deep ocean is ventilated, and is an important element in the global thermohaline circulation. Previous investigations of its variability-in particular, direct current measurements(1,2) in the overflow core since 1986-have shown surprisingly little evidence of long-term changes in now speed. Here we report significant changes in the overflow characteristics during the winter of 1996-97, measured using two current-meter moorings and an inverted echo sounder located at different depths in the fastest part of the now. The overflow warmed to the highest monthly value yet recorded (2.4 degrees C), and showed a pronounced slowing and thinning at its lower margin. We believe that the extreme warmth of the overflow caused it to run higher on the continental slope off east Greenland, so that the lower current meters and the echo sounder were temporarily outside and deeper than the fast-flowing core; model simulations appear to confirm this interpretation, We suggest that the extreme warmth of the overflow is a lagged response to a warming upstream in the Fram Strait three years earlier (caused by an exceptional amplification of the winter North Atlantic Oscillation). If this is so, over-now characteristics may be predictable.
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  • 12
    Publication Date: 2017-02-27
    Description: The ability to monitor the heat content of oceans over long distances is becoming increasingly important for understanding the role of oceans in climate change, for determining the variability of the state of the oceans, for operational ocean observing systems, and for studying large-scale ocean processes such as water-mass formation. Although the properties of the upper layers of the ocean can be routinely measured on large scales by satellite remote sensing (providing altimetric and infrared data) and with expendable probes dropped from commercial vessels, the deep interior of the ocean is more difficult to monitor. Ocean acoustic tomography1 is a promising technique for such applications, as it has the potential to provide systematic, instantaneous and repeated measurements of the ocean interior over large parts of an ocean basin. Here we demonstrate the capability of this technique for measuring the heat content across an entire (albeit small) ocean basin—the western Mediterranean Sea.
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  • 13
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    In:  Nature, 382 (6589). pp. 344-346.
    Publication Date: 2017-02-27
    Description: The conventional model whereby plume volcanism forms linear age-progressive volcanic chains, with the youngest activity occurring nearest a spreading axis (at a 'hotspot'), has been challenged for the Easter seamount chain1–4. Whereas early work suggested the existence of a linear melting anomaly (a 'hotline')1,2, more recent studies3,4 have proposed a hotspot near Salas y Gomez island, connected with the Easter microplate spreading system by an ~800-km-long, volcanically active plume channel. Here we use geochemical, geological and geochronological data to argue that the hotspot lies close to Easter Island. Moreover, new isotopic data for lavas from the seamount chain provide evidence for bidirectional flow between the spreading axis and the plume, thus supporting geophysical and fluid-dynamical models of mantle flow in a plume/spreading axis system5–7. Material balance and flux considerations show the Easter plume to be weak and cool compared with those beneath larger features such as Iceland, Hawaii and the Galápagos islands.
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  • 14
    Publication Date: 2017-02-27
    Description: A knowledge of past changes in the biological productivity of the oceans is important for understanding the interactions between carbon cycling and climate. Phytoplankton productivity in today's oceans can be estimated from the concentrations of chlorophyll in sea water1, but chlorophyll is not preserved in the sediments. Existing proxies for past algal productivity do not represent total productivity; for example, biogenic opal2 reflects the contribution of only part of the phytoplankton community, and the organic carbon record can be subject to contamination from terrestrial inputs2,3. Although chlorins, the pigment-transformation products of chlorophyll, are widespread in Quaternary marine sediments, their potential as proxy measures of past variations in primary productivity has not been convincingly demonstrated. Here we report a high-resolution molecular stratigraphic record of chlorin concentrations over the past 350,000 years in a sediment core from the subtropical Atlantic continental margin. Maxima in the chlorin accumulation rate coincide with significant peaks in the accumulation rates of biogenic opal (at the end of glacial terminations) and organic carbon (between terminations). These results suggest that chlorins, unlike other proxies, can serve as a measure of total primary productivity variations.
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  • 15
    Publication Date: 2017-02-27
    Description: The ocean stores and transports vast quantities of heat, fresh water, carbon and other materials, and its circulation plays an important role in determining both the Earth's climate and fundamental processes in the biosphere. Understanding the development of climate and important biological cycles therefore requires detailed knowledge of ocean circulation and its transport properties. This cannot be achieved solely through modelling, but must involve accurate observations of the spatio-temporal evolution of the global oceanic flow field. Estimates of oceanic flow are currently made on the basis of space-borne measurements of the sea surface, and monitoring of the ocean interior. Satellite altimetry and acoustic tomography are complementary for this purpose1, as the former provides detailed horizontal coverage of the surface, and the latter the requisite vertical sampling of the interior. High-quality acoustic-tomographic2 and altimetric3 data are now available to test the combined power of these technologies for estimating oceanic flows. Here we demonstrate that, with the aid of state-of-the-art numerical models, it is possible to recover from these data a detailed spatio-temporal record of flow over basin-scale volumes of fluid. Our present results are restricted to the Mediterranean Sea, but the method described here provides a powerful tool for studying oceanic circulation worldwide.
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  • 16
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    Nature Publishing Group
    In:  Nature, 382 . pp. 802-805.
    Publication Date: 2017-02-27
    Description: A fundamental issue in marine science is the identification of the factors controlling biological uptake of CO2, in high-nitrate, low-chlorophyll regions. A recent in situ iron fertilization experiment demonstrated that iron limitation is responsible for low phytoplankton stocks in the equatorial Pacific4. Here we show that flavodoxin, a biochemical marker of iron limitation, can be used to map the degree of iron stress in natural populations. Flavodoxin assays along a 900-km east-west transect in the northeastern subarctic Pacific revealed a pronounced increase in iron stress in the region west of the 135° W meridian. Addition of dissolved iron alleviated this stress. Immunostaining of single cells from the most western station showed that flavodoxin is present specifically within the chloroplasts of diatoms. Our approach provides a rapid means of defining the extent of iron stress in the ocean5 and supports the hypothesis that diatoms are iron stressed in the northeast Pacific.
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  • 17
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    In:  Nature, 373 . p. 28.
    Publication Date: 2017-02-27
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  • 18
    Publication Date: 2017-02-27
    Description: Seismic tomography and the isotope geochemistry of Cenozoic volcanic rocks suggest the existence of a large, sheet-like region of upwelling in the upper mantle which extends from the eastern Atlantic Ocean to central Europe and the western Mediterranean. A belt of extension and rifting in the latter two areas appears to lie above the intersection of the centre of the upwelling region with the base of the lithosphere. Lead, strontium and neodymium isotope data for all three regions converge on a restricted composition, inferred to be that of the upwelling mantle.
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  • 19
    Publication Date: 2017-02-27
    Description: THE hydrothermal circulation of sea water through permeable ocean crust results in rock–water interactions that lead to the formation of massive sulphide deposits. These are the modern analogues of many ancient ophiolite-hosted deposits1–4, such as those exposed in Cyprus. Here we report results obtained from drilling a series of holes into an actively forming sulphide deposit on the Mid-Atlantic Ridge. A complex assemblage of sulphide–anhydrite–silica breccias provides striking evidence that such hydrothermal mounds do not grow simply by the accumulation of sulphides on the sea floor. Indeed, the deposit grows largely as an in situ breccia pile, as successive episodes of hydrothermal activity each form new hydrothermal precipitates and cement earlier deposits. During inactive periods, the collapse of sulphide chimneys, dissolution of anhydrite, and disruption by faulting cause brecciation of the deposit. The abundance of anhydrite beneath the present region of focused hydrothermal venting reflects the high temperatures ( 〉 150 °C) currently maintained within the mound, and implies substantial entrainment of cold sea water into the interior of the deposit. These observations demonstrate the important role of anhydrite in the growth of massive sulphide deposits, despite its absence in those preserved on land.
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  • 20
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    Nature Publishing Group
    In:  Nature, 376 (6537). pp. 212-213.
    Publication Date: 2016-06-16
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  • 21
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    Nature Publishing Group
    In:  Nature, 397 (6718). pp. 389-391.
    Publication Date: 2015-07-16
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  • 22
    ISSN: 1476-4687
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Chemistry and Pharmacology , Medicine , Natural Sciences in General , Physics
    Notes: [Auszug] Dimerization is a biological regulatory mechanism employed by both soluble and membrane proteins. However, there are few structural data on the factors that govern dimerization of membrane proteins. Outer membrane phospholipase A (OMPLA) is an integral membrane enzyme which participates in ...
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  • 23
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    [s.l.] : Nature Publishing Group
    Nature 399.1999, Supplementary, A7-, (8 S.) 
    ISSN: 1476-4687
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Chemistry and Pharmacology , Medicine , Natural Sciences in General , Physics
    Notes: [Auszug] There is growing optimism among researchers in the field of brain ischaemia, as human stroke has at last become treatable and current research efforts delineate several new, potential therapies. Most strokes are caused by acute interruption of the brain arterial blood supply by a thrombus, leading ...
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  • 24
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    Nature 399.1999, Supplementary, A15-, (8 S.) 
    ISSN: 1476-4687
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Chemistry and Pharmacology , Medicine , Natural Sciences in General , Physics
    Notes: [Auszug] Epilepsy, a brain disorder that is characterized by recurrent seizures, refers to a collection of disorders that affect 1–2% of the population worldwide. A seizure is a brief change in behaviour caused by the disordered, synchronous and rhythmic firing of populations of neurons in the ...
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  • 25
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    Nature 399.1999, Supplementary, A23-, (9 S.) 
    ISSN: 1476-4687
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Chemistry and Pharmacology , Medicine , Natural Sciences in General , Physics
    Notes: [Auszug] Studies of the molecular basis of Alzheimer's disease exemplify the increasingly blurred distinction between basic and applied biomedical research.The four genes so far implicated in familial Alzheimer's disease have each been shown to elevate brain levels of the self-aggregating amyloid-β ...
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  • 26
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    Nature 399.1999, Supplementary, A32-, (8 S.) 
    ISSN: 1476-4687
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Chemistry and Pharmacology , Medicine , Natural Sciences in General , Physics
    Notes: [Auszug] Parkinson's disease (PD) is one of the major neurodegenerative disorders of middle and old age, and was originally described by James Parkinson in 1817. It is characterized by a trio of cardinal symptoms—muscle rigidity, tremor and bradykinesia—but can also involve postural deficits and ...
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  • 27
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    Nature 399.1999, Supplementary, A40-, (8 S.) 
    ISSN: 1476-4687
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Chemistry and Pharmacology , Medicine , Natural Sciences in General , Physics
    Notes: [Auszug] The cause of multiple sclerosis remains unknown after more than a century of study. Unconfirmed work has once more indicated that a viral infection may be important in the aetiology of the disease, and there is considerable evidence for an important genetic influence on disease susceptibility. The ...
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  • 28
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    Nature 398 (1999), S. 4-5 
    ISSN: 1476-4687
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Chemistry and Pharmacology , Medicine , Natural Sciences in General , Physics
    Notes: [Auszug] On 13 January this year, Brazil suffered a shock which, if you listen to some commentators abroad, shook it to its very core. In São Paulo the following week, however, the locals were unfazed. By Latin American standards, a devaluation of 25 per cent (later 45 per cent) is not much to get ...
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  • 29
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    Nature 398 (1999), S. 7-9 
    ISSN: 1476-4687
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Chemistry and Pharmacology , Medicine , Natural Sciences in General , Physics
    Notes: [Auszug] ...Last year, Luis Herrera-Estrella thought he saw an opportunity to use his science to contribute to Mexico's economy. Herrera-Estrella, a plant biotechnologist at the Centre for Research and Advanced Studies of the National Polytechnic Institute (CINVESTAV), was one of several scientists invited ...
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  • 30
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    Nature 398 (1999), S. 10-10 
    ISSN: 1476-4687
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Chemistry and Pharmacology , Medicine , Natural Sciences in General , Physics
    Notes: [Auszug] Even for those fortunate scientists in Latin America who manage to obtain adequate funding, have bright graduate students to work with and fast Internet links connecting them to the world of science, a major obstacle remains on the road to first-rate research: fast access to equipment and ...
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  • 31
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    Nature 398 (1999), S. 9-20 
    ISSN: 1476-4687
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Chemistry and Pharmacology , Medicine , Natural Sciences in General , Physics
    Notes: [Auszug] The challenge of combining high-quality basic research with a mission to address the country's wider needs is embodied in the experience of UNAM's Nitrogen Fixation Research Centre, in Cuernavaca. The centre was founded in 1980 with the aim of studying the molecular basis of biological nitrogen ...
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  • 32
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    Nature 398 (1999), S. 11-12 
    ISSN: 1476-4687
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Chemistry and Pharmacology , Medicine , Natural Sciences in General , Physics
    Notes: [Auszug] ...Whichever way you look at it — by the reputation of its leading researchers abroad or the orderliness of its universities, by the amount its government spends on science or the number of papers its researchers publish each year in international journals — Chile's small scientific ...
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  • 33
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    Nature 398 (1999), S. 13-13 
    ISSN: 1476-4687
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Chemistry and Pharmacology , Medicine , Natural Sciences in General , Physics
    Notes: [Auszug] ...Many astronomers regard Chile as the best place on Earth for astronomy. A stroll at night outside the dome at the Cerro Tololo Inter-American Observatory (CTIO) near La Serena in northern Chile reveals why. The sky is crystal clear, and so still that stable images of stars are a near certainty. ...
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  • 34
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    Nature 398 (1999), S. 14-15 
    ISSN: 1476-4687
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Chemistry and Pharmacology , Medicine , Natural Sciences in General , Physics
    Notes: [Auszug] ...After a hectic day fighting to save his country from currency contagion — it's Monday on the week after the Brazilian réal collapsed, and speculators have the Argentinian peso in their sights — the Argentinian chef de cabinet, Jorge Rodríguez, is relaxed and relieved to ...
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  • 35
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    Nature 398 (1999), S. 16-18 
    ISSN: 1476-4687
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Chemistry and Pharmacology , Medicine , Natural Sciences in General , Physics
    Notes: [Auszug] ...One of the least welcome tasks facing researchers at the Federal University of Rio de Janeiro — the second largest research university in Brazil — is to review grant applications from their colleagues 300 miles inland in São Paulo. “They ask for money for ...
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  • 36
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    Nature 398 (1999), S. 19-19 
    ISSN: 1476-4687
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Chemistry and Pharmacology , Medicine , Natural Sciences in General , Physics
    Notes: [Auszug] ...This year, if schedules hold, Brazil will finally realize its 20-year ambition to join the first rank of spacefaring nations. The agenda for 1999 has all the ingredients of a mature space programme, from the debut of a new Brazilian rocket to the selection of astronauts to fly on the ...
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  • 37
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    Nature 398 (1999), S. 20-21 
    ISSN: 1476-4687
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Chemistry and Pharmacology , Medicine , Natural Sciences in General , Physics
    Notes: [Auszug] ...The people of the Amazon basin are among the poorest of South America, but the region's rainforests are home to the richest diversity of life in the world. The potential of that wealth for the region was recognized implicitly for the first time in 1992, when representatives of 150 nations ...
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  • 38
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    Nature 398 (1999), S. 22-23 
    ISSN: 1476-4687
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Chemistry and Pharmacology , Medicine , Natural Sciences in General , Physics
    Notes: [Auszug] ...“Cuba's future must, by necessity, be a future of scientists,” Fidel Castro declared in 1960, soon after the Cuban revolution. Almost 40 years later, his prophesy is some way from fulfilment. But in one area of applied science — biotechnology — a concerted national effort ...
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  • 39
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    Nature 387 (1997), S. 349-350 
    ISSN: 1476-4687
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Chemistry and Pharmacology , Medicine , Natural Sciences in General , Physics
    Notes: [Auszug] Among evolutionary debates, perhaps only the origin of humans has attracted as much attention as avian origins. Less than two years after Darwin's Origin of Species hit the shelves, a spectacular 'missing link' between birds and reptiles was unearthed in Germany: the famous 'feathered reptile' ...
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  • 40
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    Nature 387 (1997), S. 355-355 
    ISSN: 1476-4687
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Chemistry and Pharmacology , Medicine , Natural Sciences in General , Physics
    Notes: [Auszug] Surface-active compounds, such as detergents and membrane lipids, have molecules in which a hydrophobic grouping is coupled to a hydrophilic one. They can stabilize a fluid interface by crowding along it as a monolayer, with the hydrophilic groups in the aqueous phase and the hydrophobic ones ...
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  • 41
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    Nature 387 (1997), S. 393-394 
    ISSN: 1476-4687
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Chemistry and Pharmacology , Medicine , Natural Sciences in General , Physics
    Notes: [Auszug] Consider an economic problem in the allocation between two alternatives Xl and X2 in which allowed values must fall on (or within) a constraint or trade-off curve, as shown in Fig. 1. Further suppose that the utility function (fitness) maximized is the simple product Xl-X2y which is equivalent to ...
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  • 42
    ISSN: 1476-4687
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Chemistry and Pharmacology , Medicine , Natural Sciences in General , Physics
    Notes: [Auszug] Many dissimilar organisms live in close association with one another. Nitrogen-fixing symbioses, in which auxotrophs exchange carbohydrates for organic nitrogen with diazotrophs, dominate numerous ecological niches. Members of the plant family Legumi-nosae, in association with the soil bacteria ...
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  • 43
    ISSN: 1476-4687
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Chemistry and Pharmacology , Medicine , Natural Sciences in General , Physics
    Notes: [Auszug] Pax6, a member of the Pax gene family, is expressed in the developing eye, nose, pancreas and central nervous system4. Studies on the spontaneous mouse mutant Small eye, in which a point mutation in the Pax6 locus results in a truncated protein, have shown that Pax6 is essential for the formation ...
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    Nature 387 (1997), S. 417-422 
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    Notes: [Auszug] The protein p 15 is an important mediator of the antiproliferative effects of TGF-p3'4. Its increased expression in response to TGF-p is sufficient to cause cell-cycle arrest in certain epithelial cells5. However, pi5INK4B/MTS2 is mutated, deleted or transcriptionally silenced in various human ...
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    Nature 387 (1997), S. 422-426 
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    Notes: [Auszug] To explore possible connections in the regulatory pathways involving Ras, Myc and Gl CDKs, we have generated a recombinant adenovirus that expresses a Ras dominant-negative mutant protein (RasN17). As shown by the experiment in Fig. la, when quiescent REF52 cells were stimulated by serum addition, ...
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    Nature 387 (1997), S. 431-432 
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    Notes: [Auszug] According to a survey of students done some years ago by DowElanco, an Indianapolis-based joint venture between Dow Chemical and Eli Lilly and Co., many students felt that scientists taking jobs in industry were not of the highest calibre and were 'money grabbers'. Their teachers, however, thought ...
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    Nature 387 (1997), S. 215-215 
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    Notes: [Auszug] Forget 100 days. Britain's new Labour government has already hit the ground running, as it had pledged. There have been some unexpected - and significant - announcements, such as the decision to give the Bank of England full independence to set interest rates. And there have also been welcome moves ...
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    Nature 387 (1997), S. 223-223 
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    Notes: [Auszug] [WASHINGTON] For a fortunate group of America's best life scientists, things will never be the same again after next Monday, 19 May. On that day, this elite will join the staff of the Howard Hughes Medical Institute (HHMI) as part of the philanthropic organization's largest expansion - their number ...
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    Nature 387 (1997), S. 226-226 
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    Notes: [Auszug] Sir- "It's the exception that proves the rule" is a phrase that is increasingly abused. It actually means that it's the exception that puts the rule to test, that is, studying exceptions leads to refinement and greater understanding of the rule or, alternatively, to the rule being discredited. ...
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    Nature 387 (1997), S. 221-221 
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    Notes: [Auszug] [PARIS] A leading British scientist and a US biotechnology company say they are keen to reach an amicable settlement over the European patent rights to so-called 'DNA-chips', a key genome technology, rather than face a protracted court battle in which either party might lose all. The patent, ...
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    Nature 387 (1997), S. 231-231 
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    Notes: [Auszug] Costanza and colleagues' summary table, Table 2 (page 256), is both fascinating and frustrating. Some numbers are small, others are huge. For none of them is there an indication of how they are obtained. How could there be in a journal with strict space limits? Nature's Web site ...
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    Nature 387 (1997), S. 221-221 
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    Notes: [Auszug] [WASHINGTON] As genetically altered crops create increasing controversy in Europe, US farmers are reported to be planting roughly ten times more acres this spring with engineered corn and soya beans than they did when the products were introduced last year. About 12 per cent of US soya bean ...
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    Nature 387 (1997), S. 237-238 
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    Notes: [Auszug] That the availability of nutrients and I light controls carbon fixation by I oceanic plants is a proposition that attracts little debate. But there has been hot discussion over just what nutrients limit this process and the applicable timescales. The traditional argument has centred around the ...
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    Nature 387 (1997), S. 243-243 
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    Notes: [Auszug] Masonry is one of the earliest and most brilliant of inventions. Merely by piling rocks or bricks on top of one another, you can assemble a structure as basic as a hut or as complicated as a cathedral. All the joints are safely in compression, and are kept stable by simple friction. (The mortar ...
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    Nature 387 (1997), S. 244-244 
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    Notes: [Auszug] Lyman Spitzer Jr (1914-97) Lyman Spitzer, who died on 31 March, shaped four different fields of science. His theoretical work on star clusters, interstellar matter and laboratory plasmas is classic. He proposed, helped to design and nurtured the construction of the Hubble Space Telescope. And he ...
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    Nature 387 (1997), S. 245-245 
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    Notes: [Auszug] A ntarctic penguins appear to be relatively /xfree of infectious diseases, although there is serological evidence of infection with a number of avian diseases found elsewhere1"4. An infectious agent is suspected in one case of mass mortality in Adelie penguin chicks, Pygoscelis adeliae5 (Fig. 1), ...
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    Nature 387 (1997), S. 237-237 
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    Notes: [Auszug] The nymph Callisto wanted to remain a virgin, like her hunting companion Artemis. Inevitably, she was seduced by Zeus (or Jupiter), and then got turned into a bear for her pains by the jealous Hera. But sometimes the real world is kinder than myth: the Galileo spacecraft has discovered that ...
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    Nature 387 (1997), S. 239-239 
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    Notes: [Auszug] 100 YEARS AGO Messrs. John Walker and Co., Ltd., have sent us several packets of their "Perfection Envelope," which have been designed to do away with the necessity of licking, or otherwise moistening, the gum on the flap of an envelope in order to make it adhere. The gum is placed upon the ...
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    Nature 387 (1997), S. 242-243 
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    Notes: [Auszug] RNA editing describes the processes that change the information content of RNA from that encoded in the gene. The term encompasses a series of distinct traits with separate origins, although it does not include messenger-RNA splicing or hypermodification of bases in transfer RNA. But it can involve ...
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    Nature 387 (1997), S. 246-246 
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    Notes: [Auszug] In their Letter to Nature1, Petridou et al attributed an increased incidence of infant leukaemia in Greece to increased in utero exposure to ionizing radiation arising from the Chernobyl accident, which occurred on 26 April 1986. We see a similar increase in infant leukaemia in western Germany in ...
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    Nature 387 (1997), S. 247-247 
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    Notes: [Auszug] Genetic recombination is known to be a source of mitochondrial DNA (mtDNA) variability in plants, fungi and protists1, but there continues to be a consensus (based on studies of somatic cell hybridization2 and DNA repair3) that such processes do not operate on animal mtDNA4. Contrary to this ...
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    Notes: [Auszug] Petridou et al. reply - The increase in incidence of leukaemia among infants exposed in utero to radiation from the Chernobyl accident in Germany is strikingly similar to that noted in Greece. No explanation other than an in utero effect of ionizing radiation or a highly improbable chance ...
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    Nature 387 (1997), S. 250-250 
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    Notes: [Auszug] Being a scientist gives Stephen Jay Gould a continuing sense of privilege and reward. Science is for him the best technique we have for gaining knowledge about the world. He sees relativism - the argument that science is merely a social construct - as "perniciously wrongheaded", and dismisses ...
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    Notes: [Auszug] The work of Antoine Lavoisier (1743-1794) marked a turning point in the history of chemistry. Following the 'chemical revolution' of the late eighteenth century, of which he was the central figure, chemistry emerged almost as a new science. Indeed, it became the model science at a time when physics ...
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    Nature 387 (1997), S. 249-249 
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    Notes: [Auszug] A mixture of cyclohexane and aniline, when above room temperature, forms a single phase, but on cooling separates into two layers. On warming up, fluctuations in the interface increase in magnitude and wavelength, and the interface then vanishes at the critical temperature where the single phase ...
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    Nature 387 (1997), S. 278-281 
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    Notes: [Auszug] Plasticity at parallel fibre synapses was tested in an in vitro slice preparation from the electrosensory lobe of the mormyrid electric fish Gnathonemus petersii. Afferents from electroreceptors terminate in the electrosensory lobe (Fig. la). All recordings were taken from GABAergic Purkinje-like ...
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    Nature 387 (1997), S. 285-288 
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    Notes: [Auszug] Both the olfactory bulb and the antennal lobe have a glomerular structure with lateral connections between glomeruli, and process incoming signals from broadly tuned odorant receptors1'2'11'13. Recordings of glomerular output neurons in insects and vertebrates indicate distributed odour ...
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    Nature 387 (1997), S. 292-295 
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    Notes: [Auszug] Rho family p21 GTPases have previously been widely studied as regulators of the actin cytoskeleton10, and more recently as components of signal transduction cascades11. Studies of Rho family p21 GTPases in Drosophila using dominant-negative or constitutively activated forms have suggested possible ...
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    Notes: [Auszug] Sequence analysis of clones isolated from a rat striatum cDNA library predicted the presence of valine (GTG), serine (ACT) and valine (GTT) codons within the second intracellular loop of the 5-HT2cR; instead, isoleucine (ATA), asparagine (AAT) and isoleucine (ATT) codons were found in the genomic ...
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    Nature 387 (1997), S. 308-312 
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    Notes: [Auszug] Relaxed striated muscle possesses markedly nonlinear visco-elastic properties, including stress-relaxation and hysteresis. The steady-state force-extension relationship is at first roughly exponential, but at extreme stretch there is a yield point, after which the curve is less steep. Elasticity ...
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    Notes: [Auszug] Lab Renovation Guide From Fisher Hamilton A 12-page brochure to help laboratory managers develop awareness of the many variables involved in renovation projects Awareness of all the factors involved in designing and managing a lab can contribute to ...
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    Nature 387 (1997), S. 109-110 
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    Notes: [Auszug] [PARIS] Time is fast running out for research organizations that have not yet tested their information technology systems for the Millennium bug' - a programming glitch in many microprocessors which will prevent them from recognizing the year 2000. This, at least, is the growing consensus among ...
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    Notes: [Auszug] [WASHINGTON] A controversial US military spacecraft mission to fire a probe into an asteroid's surface may finally get off the ground in 1999 if Congress commits additional funding for next year, and if the National Aeronautics and Space Administration (NASA) offers a free ride on the Space ...
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    Nature 387 (1997), S. 111-111 
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    Notes: [Auszug] [RABS] Germany's research minister, Jurgen Ruttgers, last week backed a call by the French president, Jacques Chirac, for a worldwide ban on human cloning. Chirac, who made the statement on the same day he received a commissioned report on the subject from the French national bioethtos committee, ...
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    Nature 387 (1997), S. 112-112 
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    Notes: [Auszug] [WASHINGTON] Jack Gibbons, science adviser to President Bill Clinton, has countered growing speculation about his future in the post in a statement saying that he is staying put - but "may desire to leave near the end of the year" Gibbons issued the statement in response to reports that John Deutch ...
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    Notes: [Auszug] [WASHNGTON] A review team of 60 experts wilt descend on Oak Ridge National Laboratory, Tennessee, next month to assess its proposal for a new spallation neutron source which could propel the United States back into the lead in neutron science. Officials from the European Spallation ...
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    Notes: [Auszug] [WASHINGTON] The US Department of Energy announced last week that it was sacking Associated Universities Incorporated (AUI), the contractor that has run Brookhaven National Laboratory on Long Island, New York, for 50 years, after an internal report criticized management and environmental procedures ...
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    Notes: [Auszug] [LISBON, PORTUGAL] Over the next few weeks, the Portuguese government will put the finishing touches to a series of reforms designed to help equip the country with the science infrastructure needed to help its economy catch up with those of its European partners. In financial terms, Portugal ...
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    Nature 387 (1997), S. 119-119 
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    Notes: [Auszug] Sir- If there were no other reasons to argue against cloning humans, Mike Fainzilber gives at least one very good one (Nature 386,431; 1997). His use of cloning a child dying in an accident as an example of'good' cloning suggests a concept of life reduced to running a genetic code. Cloning a dying ...
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    Nature 387 (1997), S. 121-121 
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    Notes: [Auszug] In 1985, global oil consumption was 59.7 million barrels per day1; by 1995 it was more than 69 million barrels per day2. This 16 per cent rise in demand was supplied almost entirely by an increase in oil production by members of the Organization of Petroleum Exporting Countries (OPEC) - mostly in ...
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    Notes: [Auszug] With black humour the microbiolo-gist asks, "What's the difference between true love and a herpesvirus infection? Herpes is forever". Like it or not, this is a brutal reminder of the difficulties of ridding the body of some of its most abiding visitors. Re-activation of the childhood chickenpox ...
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    Nature 387 (1997), S. 126-127 
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    Notes: [Auszug] Body mass is a critical determinant of many aspects of an organism's physiology, adaptations and behaviour. Because body mass can easily be quantified for living forms, and because it correlates strongly with life-history parameters such as metabolic rate, longevity and gestation length, much ...
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    Notes: [Auszug] The spectrograph Is a device that converts speech signals into a three-dimensional visual representation, the spectrogram. Variations in intensity are represented by the darkness of the trace. Variations in frequency are represented on the y-axis, and time isshown on the a the 1950s, a 'pattern ...
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    Notes: [Auszug] Eukaryotic cells rely on a series of membrane-bound organelles to compartmentalize biochemical reactions and to regulate the secretion and localization of proteins. Although each organelle has a unique molecular composition, giving it a distinct functional identity, membranes and proteins are ...
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    Nature 387 (1997), S. 143-144 
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    Notes: [Auszug] The two great foundations of twentieth-century physics are quantum theory and relativity. In 1987, Tony Hey and Patrick Walters wrote The Quantum Universe, a liberally illustrated and highly successful book showing how the arcane quantum theory affects our daily experience. They have now followed ...
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    Notes: [Auszug] Mice lacking the imprinted Cdk inhibitor p57KIP2 have altered cell proliferation and differentiation, leading to abdominal muscle defects; cleft palate; endochondral bone ossification defects with incomplete differentiation of hypertrophic chondrocytes; renal medullary dysplasia; ...
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    Nature 387 (1997), S. 164-166 
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    Notes: [Auszug] The chances of success from the point of view of vaccinology will be higher with the greater specificity of the carbohydrate domain of the antigen. From this perspective, one such tumour antigen which attracted our notice is the glycolipid KH-1, immunocharacterized by Hakomori and associates9. (We ...
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    Nature 387 (1997), S. 173-176 
    ISSN: 1476-4687
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Chemistry and Pharmacology , Medicine , Natural Sciences in General , Physics
    Notes: [Auszug] It is generally acknowledged, even by those who have used other methods, that the best means of estimating body mass from skeletal or fossil remains, when feasible, is to use features that have some direct functional relationship to body mass9'11'12. For hominids, the skeletal dimensions used most ...
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    Notes: [Auszug] Eight HIV-1-infected patients were studied who were naive to antiretroviral agents, with baseline CD4 lymphocyte counts ranging from 26 to 505 per juil (Table 1). De novo HIV-1 replication in the patients was blocked by the combined use of a protease inhibitor, nelfinavir4 (2,250 mg d *), ...
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    Nature 387 (1997), S. 195-199 
    ISSN: 1476-4687
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Chemistry and Pharmacology , Medicine , Natural Sciences in General , Physics
    Notes: [Auszug] Male-specific lethal-2 (ras/2) encodes a key male-limited regulator of dosage compensation in Drosophila. The MSL proteins function as a multisubunit complex bound to hundreds of sites on the male X chromosome, where they are postulated to recruit the MOF (males absent on the first) histone ...
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    Nature 387 (1997), S. 211-214 
    ISSN: 1476-4687
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Chemistry and Pharmacology , Medicine , Natural Sciences in General , Physics
    Notes: [Auszug] HP G2500A GeneArray scanner From Hewlett-Packard A genetic analysis system designed to scan Affymetrix GeneChip probe arrays These single-use probe arrays have thousands of probe features that can sequence or identify multiple genes in a ...
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    Nature 386 (1997), S. 743-743 
    ISSN: 1476-4687
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Chemistry and Pharmacology , Medicine , Natural Sciences in General , Physics
    Notes: [Auszug] Japan is abuzz this week with calls for PNC, a semi-government organization (tokushu hojin) responsible for research and development in nuclear power, to be dissolved following a series of scandalous attempts by PNC officials to cover up mistakes made in accidents at its facilities (see page 746). ...
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    Nature 386 (1997), S. 747-747 
    ISSN: 1476-4687
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Chemistry and Pharmacology , Medicine , Natural Sciences in General , Physics
    Notes: [Auszug] [WASHINGTON] The head of the US Patent and Trademark Office has replied to criticism from the National Institutes of Health (NIH) about the office's decision to allow the patenting of short DNA sequences known as expressed sequence tags (ESTs) on the basis of their utility as molecular probes. ...
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    Nature 386 (1997), S. 748-748 
    ISSN: 1476-4687
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Chemistry and Pharmacology , Medicine , Natural Sciences in General , Physics
    Notes: [Auszug] [WASHINGTON] A committee of the US House of Representatives gave backhanded endorsements to two controversial international programmes last week, authorizing US funding for both the International Space Station and the Large Hadron Collider (LHC) at the European Laboratory for Particle Physics ...
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    Nature 386 (1997), S. 754-754 
    ISSN: 1476-4687
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Chemistry and Pharmacology , Medicine , Natural Sciences in General , Physics
    Notes: [Auszug] Sir - In a recent News story about the sequencing of the Escherichia coli genome (Nature3&5,472; 1997) you said that "the unannotated Japanese sequence is a hybrid of more than one strain"; you also said "So far, however, only raw sequence data are available in the public database" (my italics ...
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    Nature 386 (1997), S. 755-755 
    ISSN: 1476-4687
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Chemistry and Pharmacology , Medicine , Natural Sciences in General , Physics
    Notes: [Auszug] Sir - A recent News story described a report which concludes that the increasing popularity of herbal medicine in the Western world is threatening its natural base, medicinal plants growing in the wild (Nature3S5,570; 1997). It also refers to Germany as being the largest consumer of these medicinal ...
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    Nature 386 (1997), S. 759-760 
    ISSN: 1476-4687
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Chemistry and Pharmacology , Medicine , Natural Sciences in General , Physics
    Notes: [Auszug] The question I am asked most frequently about Ca2+ is how such a simple messenger can regulate so many diverse cellular processes, such as fertilization, secretion, contraction, proliferation, neural signalling and learning. With much hand waving, I usually speculate that such diversity might be ...
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    Nature 386 (1997), S. 764-765 
    ISSN: 1476-4687
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Chemistry and Pharmacology , Medicine , Natural Sciences in General , Physics
    Notes: [Auszug] Were science to be judged on entertainment value alone, there is little doubt that the fastest route to the glittering prizes would be to work on fossil DNA. If you doubt that, take a look at the British tabloids of 9 March, where a report linking the DNA from a Palaeolithic tooth to a ...
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    Nature 386 (1997), S. 767-769 
    ISSN: 1476-4687
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Chemistry and Pharmacology , Medicine , Natural Sciences in General , Physics
    Notes: [Auszug] Since 1991, at least a dozen human genetic diseases have been shown to be caused by unstable expansions of tri-nucleotide repeats1 (Fig. 1, overleaf). The discovery of these expansions was a surprise because they had not been described in other organisms, but it led to a tendency to derive general ...
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    Nature 386 (1997), S. 770-770 
    ISSN: 1476-4687
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Chemistry and Pharmacology , Medicine , Natural Sciences in General , Physics
    Notes: [Auszug] Animals inhabit a sort of Garden of Eden. Everything they d& they do because they feel like it at the time. Their key motivation is excitement. Human beings have lost that hofy simplicity. We have invented rational expectations, and with them, work - which is anyactavitvr whether undertaken in ...
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