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  • Articles  (50)
  • Protein-nucleic acid interaction  (19)
  • 04. Solid Earth::04.07. Tectonophysics::04.07.07. Tectonics  (18)
  • 04. Solid Earth::04.04. Geology::04.04.05. Mineralogy and petrology
  • Elsevier  (28)
  • Oxford University Press  (21)
  • American Institute of Physics (AIP)
  • Copernicus
  • Wiley
  • 2010-2014  (50)
  • 1995-1999
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  • Articles  (50)
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  • 1
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    A comparative analysis of transcription factor binding models learned from PBM, HT-SELEX and ChIP data (2014)
    Oxford University Press
    Details
    Publication Date: 2014-05-01
    Description: Understanding gene regulation is a key challenge in today's biology. The new technologies of protein-binding microarrays (PBMs) and high-throughput SELEX (HT-SELEX) allow measurement of the binding intensities of one transcription factor (TF) to numerous synthetic double-stranded DNA sequences in a single experiment. Recently, Jolma et al. reported the results of 547 HT-SELEX experiments covering human and mouse TFs. Because 162 of these TFs were also covered by PBM technology, for the first time, a large-scale comparison between implementations of these two in vitro technologies is possible. Here we assessed the similarities and differences between binding models, represented as position weight matrices, inferred from PBM and HT-SELEX, and also measured how well these models predict in vivo binding. Our results show that HT-SELEX- and PBM-derived models agree for most TFs. For some TFs, the HT-SELEX-derived models are longer versions of the PBM-derived models, whereas for other TFs, the HT-SELEX models match the secondary PBM-derived models. Remarkably, PBM-based 8-mer ranking is more accurate than that of HT-SELEX, but models derived from HT-SELEX predict in vivo binding better. In addition, we reveal several biases in HT-SELEX data including nucleotide frequency bias, enrichment of C-rich k-mers and oligos and underrepresentation of palindromes.
    Keywords: Protein-nucleic acid interaction
    Print ISSN: 0305-1048
    Electronic ISSN: 1362-4962
    Topics: Biology
    Published by Oxford University Press
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  • 2
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    Snapshots of pre-rRNA structural flexibility reveal eukaryotic 40S assembly dynamics at nucleotide resolution (2014)
    Oxford University Press
    Details
    Publication Date: 2014-11-07
    Description: Ribosome assembly in eukaryotes involves the activity of hundreds of assembly factors that direct the hierarchical assembly of ribosomal proteins and numerous ribosomal RNA folding steps. However, detailed insights into the function of assembly factors and ribosomal RNA folding events are lacking. To address this, we have developed ChemModSeq, a method that combines structure probing, high-throughput sequencing and statistical modeling, to quantitatively measure RNA structural rearrangements during the assembly of macromolecular complexes. By applying ChemModSeq to purified 40S assembly intermediates we obtained nucleotide-resolution maps of ribosomal RNA flexibility revealing structurally distinct assembly intermediates and mechanistic insights into assembly dynamics not readily observed in cryo-electron microscopy reconstructions. We show that RNA restructuring events coincide with the release of assembly factors and predict that completion of the head domain is required before the Rio1 kinase enters the assembly pathway. Collectively, our results suggest that 40S assembly factors regulate the timely incorporation of ribosomal proteins by delaying specific folding steps in the 3' major domain of the 20S pre-ribosomal RNA.
    Keywords: Protein-nucleic acid interaction
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    Topics: Biology
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  • 3
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    Identification of target-binding peptide motifs by high-throughput sequencing of phage-selected peptides (2014)
    Oxford University Press
    Details
    Publication Date: 2014-12-17
    Description: High-throughput sequencing was previously applied to phage-selected peptides in order to gain insight into the abundance and diversity of isolated peptides. Herein we developed a procedure to efficiently compare the sequences of large numbers of phage-selected peptides for the purpose of identifying target-binding peptide motifs. We applied the procedure to analyze bicyclic peptides isolated against five different protein targets: sortase A, urokinase-type plasminogen activator, coagulation factor XII, plasma kallikrein and streptavidin. We optimized sequence data filters to reduce biases originating from the sequencing method and developed sequence correction algorithms to prevent identification of false consensus motifs. With our strategy, we were able to identify rare target-binding peptide motifs, as well as to define more precisely consensus sequences and sub-groups of consensus sequences. This information is valuable to choose peptide leads for drug development and it facilitates identification of epitopes. We furthermore show that binding motifs can be identified after a single round of phage selection. Such a selection regimen reduces propagation-related bias and may facilitate application of phage display in non-specialized laboratories, as procedures such as bacterial infection, phage propagation and purification are not required.
    Keywords: Protein-nucleic acid interaction
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    Electronic ISSN: 1362-4962
    Topics: Biology
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  • 4
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    Competitive binding-based optical DNA mapping for fast identification of bacteria - multi-ligand transfer matrix theory and experimental applications on Escherichia coli (2014)
    Oxford University Press
    Details
    Publication Date: 2014-09-02
    Description: We demonstrate a single DNA molecule optical mapping assay able to resolve a specific Escherichia coli strain from other strains. The assay is based on competitive binding of the fluorescent dye YOYO-1 and the AT-specific antibiotic netropsin. The optical map is visualized by stretching the DNA molecules in nanofluidic channels. We optimize the experimental conditions to obtain reproducible barcodes containing as much information as possible. We implement a multi-ligand transfer matrix method for calculating theoretical barcodes from known DNA sequences. Our method extends previous theoretical approaches for competitive binding of two types of ligands to many types of ligands and introduces a recursive approach that allows long barcodes to be calculated with standard computer floating point formats. The identification of a specific E . coli strain (CCUG 10979) is based on mapping of 50–160 kilobasepair experimental DNA fragments onto the theoretical genome using the developed theory. Our identification protocol introduces two theoretical constructs: a P -value for a best experiment-theory match and an information score threshold. The developed methods provide a novel optical mapping toolbox for identification of bacterial species and strains. The protocol does not require cultivation of bacteria or DNA amplification, which allows for ultra-fast identification of bacterial pathogens.
    Keywords: Protein-nucleic acid interaction
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    Topics: Biology
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  • 5
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    Quantifying sequence and structural features of protein-RNA interactions (2014)
    Oxford University Press
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    Publication Date: 2014-09-02
    Description: Increasing awareness of the importance of protein–RNA interactions has motivated many approaches to predict residue-level RNA binding sites in proteins based on sequence or structural characteristics. Sequence-based predictors are usually high in sensitivity but low in specificity; conversely structure-based predictors tend to have high specificity, but lower sensitivity. Here we quantified the contribution of both sequence- and structure-based features as indicators of RNA-binding propensity using a machine-learning approach. In order to capture structural information for proteins without a known structure, we used homology modeling to extract the relevant structural features. Several novel and modified features enhanced the accuracy of residue-level RNA-binding propensity beyond what has been reported previously, including by meta-prediction servers. These features include: hidden Markov model-based evolutionary conservation, surface deformations based on the Laplacian norm formalism, and relative solvent accessibility partitioned into backbone and side chain contributions. We constructed a web server called aaRNA that implements the proposed method and demonstrate its use in identifying putative RNA binding sites.
    Keywords: Protein-nucleic acid interaction
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    Topics: Biology
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  • 6
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    Ultrasensitive isolation, identification and quantification of DNA-protein adducts by ELISA-based RADAR assay (2014)
    Oxford University Press
    Details
    Publication Date: 2014-08-01
    Description: Enzymes that form transient DNA–protein covalent complexes are targets for several potent classes of drugs used to treat infectious disease and cancer, making it important to establish robust and rapid procedures for analysis of these complexes. We report a method for isolation of DNA–protein adducts and their identification and quantification, using techniques compatible with high-throughput screening. This method is based on the RADAR assay for DNA adducts that we previously developed (Kiianitsa and Maizels (2013) A rapid and sensitive assay for DNA–protein covalent complexes in living cells. Nucleic Acids Res. , 41:e104), but incorporates three key new steps of broad applicability. (i) Silica-assisted ethanol/isopropanol precipitation ensures reproducible and efficient recovery of DNA and DNA–protein adducts at low centrifugal forces, enabling cell culture and DNA precipitation to be carried out in a single microtiter plate. (ii) Rigorous purification of DNA–protein adducts by a procedure that eliminates free proteins and free nucleic acids, generating samples suitable for detection of novel protein adducts (e.g. by mass spectroscopy). (iii) Identification and quantification of DNA–protein adducts by direct ELISA assay. The ELISA-based RADAR assay can detect Top1–DNA and Top2a–DNA adducts in human cells, and gyrase–DNA adducts in Escherichia coli . This approach will be useful for discovery and characterization of new drugs to treat infectious disease and cancer, and for development of companion diagnostics assays for individualized medicine.
    Keywords: Protein-nucleic acid interaction
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    Topics: Biology
    Published by Oxford University Press
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  • 7
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    Magnetic fabric of Plio-Pleistocene sediments from the Crotone fore-arc basin: Insights on the recent tectonic evolution of the Calabrian Arc (Italy) (2014)
    Elsevier
    Details
    Publication Date: 2020-12-07
    Description: Low-field anisotropy of magnetic susceptibility (AMS) analyses were performed on 532 samples col-lected in 36 (mostly lower Pliocene to lower Pleistocene) marine clay sites from the Crotone basin, afore-arc basin located on top of the external Calabrian accretionary wedge. The Crotone basin formedsince mid-late Miocene under a predominant extensional tectonic regime, but it was influenced there-after by complex interactions with NW–SE left-lateral strike-faults bounding the basin, which also yieldedpost-1.2 Ma ~30◦counterclockwise block rotations. The basin is filled by continental to marine sedimentsyielding one of the thickest and best-exposed Neogene succession available worldwide. The deep-marinefacies – represented by blue-grey marly clays gave the best results, as they both preserved a clear mag-netic fabric, and provided accurate chronology based on previously published magnetostratigraphy andcalcareous plankton (i.e. foraminifers and nannofossils) biostratigraphy. Magnetic susceptibility rangeand rock magnetic analyses both indicate that AMS reflects paramagnetic clay matrix crystal arrange-ment. The fabric is predominantly oblate to triaxial, the anisotropy degree low (〈1.06), and the magneticfoliation mostly subparallel to bedding. Magnetic lineation is defined in 30 out of 36 sites (where thee12 angle is 〈35◦). By also considering local structural analysis data, we find that magnetic fabric wasgenerally acquired during the first tectonic phases occurring after sediment deposition, thus validatingits use as temporally dependent strain proxy. Although most of the magnetic lineations trend NW–SE andare orthogonal to normal faults (as observed elsewhere in Calabria), few NE–SW compressive lineationsshow that the Neogene extensional regime of the Crotone basin was punctuated by compressive episodes.Finally, compressive lineations (prolate magnetic fabric) documented along the strike-slip fault boundingthe basin to the south support the significance of Pleistocene strike-slip tectonics. Thus the Crotone basinshows a markedly different tectonics with respect to other internal and western basins of Calabria, asit yields a magnetic fabric still dominated by extensional tectonics but also revealing arc-normal short-ening episodes and recent strike-slip fault activity. The tectonics documented in the Crotone basin iscompatible with a continuous upper crustal structural reorganization occurring during the SE-migrationof the Calabria terrane above the Ionian subduction system.
    Description: Published
    Description: 67-79
    Description: 1A. Geomagnetismo e Paleomagnetismo
    Description: JCR Journal
    Description: restricted
    Keywords: Calabrian Arc, Anisotropy of magnetic susceptibility, Structural analysis, Fore-arc region ; 04. Solid Earth::04.04. Geology::04.04.08. Sediments: dating, processes, transport ; 04. Solid Earth::04.04. Geology::04.04.09. Structural geology ; 04. Solid Earth::04.05. Geomagnetism::04.05.06. Paleomagnetism ; 04. Solid Earth::04.05. Geomagnetism::04.05.07. Rock magnetism ; 04. Solid Earth::04.07. Tectonophysics::04.07.02. Geodynamics ; 04. Solid Earth::04.07. Tectonophysics::04.07.07. Tectonics
    Repository Name: Istituto Nazionale di Geofisica e Vulcanologia (INGV)
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  • 8
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    Single-molecule sorting reveals how ubiquitylation affects substrate recognition and activities of FBH1 helicase (2013)
    Oxford University Press
    Details
    Publication Date: 2013-04-02
    Description: DNA repair helicases function in the cell to separate DNA duplexes or remodel nucleoprotein complexes. These functions are influenced by sensing and signaling; the cellular pool of a DNA helicase may contain subpopulations of enzymes carrying different post-translational modifications and performing distinct biochemical functions. Here, we report a novel experimental strategy, single-molecule sorting, which overcomes difficulties associated with comprehensive analysis of heterologously modified pool of proteins. This methodology was applied to visualize human DNA helicase F-box–containing DNA helicase (FBH1) acting on the DNA structures resembling a stalled or collapsed replication fork and its interactions with RAD51 nucleoprotein filament. Individual helicase molecules isolated from human cells with their native post-translational modifications were analyzed using total internal reflection fluorescence microscopy. Separation of the activity trajectories originated from ubiquitylated and non-ubiquitylated FBH1 molecules revealed that ubiquitylation affects FBH1 interaction with the RAD51 nucleoprotein filament, but not its translocase and helicase activities.
    Keywords: Protein-nucleic acid interaction
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  • 9
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    RIPSeeker: a statistical package for identifying protein-associated transcripts from RIP-seq experiments (2013)
    Oxford University Press
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    Publication Date: 2013-04-23
    Description: RIP-seq has recently been developed to discover genome-wide RNA transcripts that interact with a protein or protein complex. RIP-seq is similar to both RNA-seq and ChIP-seq, but presents unique properties and challenges. Currently, no statistical tool is dedicated to RIP-seq analysis. We developed RIPSeeker ( http://www.bioconductor.org/packages/2.12/bioc/html/RIPSeeker.html ), a free open-source Bioconductor/R package for de novo RIP peak predictions based on HMM. To demonstrate the utility of the software package, we applied RIPSeeker and six other published programs to three independent RIP-seq datasets and two PAR-CLIP datasets corresponding to six distinct RNA-binding proteins. Based on receiver operating curves, RIPSeeker demonstrates superior sensitivity and specificity in discriminating high-confidence peaks that are consistently agreed on among a majority of the comparison methods, and dominated 9 of the 12 evaluations, averaging 80% area under the curve. The peaks from RIPSeeker are further confirmed based on their significant enrichment for biologically meaningful genomic elements, published sequence motifs and association with canonical transcripts known to interact with the proteins examined. While RIPSeeker is specifically tailored for RIP-seq data analysis, it also provides a suite of bioinformatics tools integrated within a self-contained software package comprehensively addressing issues ranging from post-alignments’ processing to visualization and annotation.
    Keywords: Protein-nucleic acid interaction
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    Topics: Biology
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  • 10
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    DNA target sequence identification mechanism for dimer-active protein complexes (2013)
    Oxford University Press
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    Publication Date: 2013-02-20
    Description: Sequence-specific DNA-binding proteins must quickly and reliably localize specific target sites on DNA. This search process has been well characterized for monomeric proteins, but it remains poorly understood for systems that require assembly into dimers or oligomers at the target site. We present a single-molecule study of the target-search mechanism of protelomerase TelK, a recombinase-like protein that is only active as a dimer. We show that TelK undergoes 1D diffusion on non-target DNA as a monomer, and it immobilizes upon dimerization even in the absence of a DNA target site. We further show that dimeric TelK condenses non-target DNA, forming a tightly bound nucleoprotein complex. Together with theoretical calculations and molecular dynamics simulations, we present a novel target-search model for TelK, which may be generalizable to other dimer and oligomer-active proteins.
    Keywords: Protein-nucleic acid interaction
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  • 11
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    Systematic screens of proteins binding to synthetic microRNA precursors (2013)
    Oxford University Press
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    Publication Date: 2013-02-02
    Description: We describe a new, broadly applicable methodology for screening in parallel interactions of RNA-binding proteins (RBPs) with large numbers of microRNA (miRNA) precursors and for determining their affinities in native form in the presence of cellular factors. The assays aim at identifying pre-miRNAs that are potentially affected by the selected RBP during their biogenesis. The assays are carried out in microtiter plates and use chemiluminescent readouts. Detection of bound RBPs is achieved by protein or tag-specific antibodies allowing crude cell lysates to be used as a source of RBP. We selected 70 pre-miRNAs with phylogenetically conserved loop regions and 25 precursors of other well-characterized miRNAs for chemical synthesis in 3'-biotinylated form. An equivalent set in unmodified form served as inhibitors in affinity determinations. By testing three RBPs known to regulate miRNA biogenesis on this set of pre-miRNAs, we demonstrate that Lin28 and hnRNP A1 from cell lysates or as recombinant protein domains recognize preferentially precursors of the let-7 family, and that KSRP binds strongly to pre-miR-1-2.
    Keywords: Protein-nucleic acid interaction
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  • 12
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    A rapid and sensitive assay for DNA-protein covalent complexes in living cells (2013)
    Oxford University Press
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    Publication Date: 2013-05-04
    Description: A number of proteins form covalent bonds with DNA as obligatory transient intermediates in normal nuclear transactions. Drugs that trap these complexes have proven to be potent therapeutics in both cancer and infectious disease. Nonetheless, current assays for DNA–protein adducts are cumbersome, limiting both mechanistic studies and translational applications. We have developed a rapid and sensitive assay that enables quantitative immunodetection of protein–DNA adducts. This new ‘RADAR’ (rapid approach to DNA adduct recovery) assay accelerates processing time 4-fold, increases sample throughput 20-fold and requires 50-fold less starting material than the current standard. It can be used to detect topoisomerase 1-DNA adducts in as little as 60 ng of DNA, corresponding to 10 000 human cells. We apply the RADAR assay to demonstrate that expression of SLFN11 does not increase camptothecin sensitivity by promoting accumulation of topoisomerase 1-DNA adducts. The RADAR assay will be useful for analysis of the mechanisms of formation and resolution of DNA–protein adducts in living cells, and identification and characterization of reactions in which covalent DNA adducts are transient intermediates. The assay also has potential application to drug discovery and individualized medicine.
    Keywords: Protein-nucleic acid interaction
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  • 13
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    Investigation of DNA sequence recognition by a streptomycete MarR family transcriptional regulator through surface plasmon resonance and X-ray crystallography (2013)
    Oxford University Press
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    Publication Date: 2013-08-09
    Description: Consistent with their complex lifestyles and rich secondary metabolite profiles, the genomes of streptomycetes encode a plethora of transcription factors, the vast majority of which are uncharacterized. Herein, we use Surface Plasmon Resonance (SPR) to identify and delineate putative operator sites for SCO3205, a MarR family transcriptional regulator from Streptomyces coelicolor that is well represented in sequenced actinomycete genomes. In particular, we use a novel SPR footprinting approach that exploits indirect ligand capture to vastly extend the lifetime of a standard streptavidin SPR chip. We define two operator sites upstream of sco3205 and a pseudopalindromic consensus sequence derived from these enables further potential operator sites to be identified in the S. coelicolor genome. We evaluate each of these through SPR and test the importance of the conserved bases within the consensus sequence. Informed by these results, we determine the crystal structure of a SCO3205-DNA complex at 2.8 Å resolution, enabling molecular level rationalization of the SPR data. Taken together, our observations support a DNA recognition mechanism involving both direct and indirect sequence readout.
    Keywords: Protein-nucleic acid interaction
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  • 14
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    A rapid assay for affinity and kinetics of molecular interactions with nucleic acids (2012)
    Oxford University Press
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    Publication Date: 2012-04-15
    Description: The Differential Radial Capillary Action of Ligand Assay (DRaCALA) allows detection of protein interactions with low-molecular weight ligands based on separation of the protein–ligand complex by differential capillary action. Here, we present an application of DRaCALA to the study of nucleic acid–protein interactions using the Escherichia coli cyclic AMP receptor protein (CRP). CRP bound in DRaCALA specifically to 32 P-labeled oligonucleotides containing the consensus CRP binding site, but not to oligonucleotides with point mutations known to abrogate binding. Affinity and kinetic studies using DRaCALA yielded a dissociation constant and dissociation rate similar to previously reported values. Because DRaCALA is not subject to ligand size restrictions, whole plasmids with a single CRP-binding site were used as probes, yielding similar results. DNA can also function as an easily labeled carrier molecule for a conjugated ligand. Sequestration of biotinylated nucleic acids by streptavidin allowed nucleic acids to take the place of the protein as the immobile binding partner. Therefore, any molecular interactions involving nucleic acids can be tested. We demonstrate this principle utilizing a bacterial riboswitch that binds cyclic-di-guanosine monophosphate. DRaCALA is a flexible and complementary approach to other biochemical methods for rapid and accurate measurements of affinity and kinetics at near-equilibrium conditions.
    Keywords: Protein-nucleic acid interaction
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  • 15
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    Combining H/D exchange mass spectroscopy and computational docking reveals extended DNA-binding surface on uracil-DNA glycosylase (2012)
    Oxford University Press
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    Publication Date: 2012-07-22
    Description: X-ray crystallography provides excellent structural data on protein–DNA interfaces, but crystallographic complexes typically contain only small fragments of large DNA molecules. We present a new approach that can use longer DNA substrates and reveal new protein–DNA interactions even in extensively studied systems. Our approach combines rigid-body computational docking with hydrogen/deuterium exchange mass spectrometry (DXMS). DXMS identifies solvent-exposed protein surfaces; docking is used to create a 3-dimensional model of the protein–DNA interaction. We investigated the enzyme uracil-DNA glycosylase (UNG), which detects and cleaves uracil from DNA. UNG was incubated with a 30 bp DNA fragment containing a single uracil, giving the complex with the abasic DNA product. Compared with free UNG, the UNG–DNA complex showed increased solvent protection at the UNG active site and at two regions outside the active site: residues 210–220 and 251–264. Computational docking also identified these two DNA-binding surfaces, but neither shows DNA contact in UNG–DNA crystallographic structures. Our results can be explained by separation of the two DNA strands on one side of the active site. These non-sequence-specific DNA-binding surfaces may aid local uracil search, contribute to binding the abasic DNA product and help present the DNA product to APE-1, the next enzyme on the DNA-repair pathway.
    Keywords: Protein-nucleic acid interaction
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  • 16
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    High-throughput single-molecule analysis of DNA-protein interactions by tethered particle motion (2012)
    Oxford University Press
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    Publication Date: 2012-06-28
    Description: Tethered particle motion (TPM) monitors the variations in the effective length of a single DNA molecule by tracking the Brownian motion of a bead tethered to a support by the DNA molecule. Providing information about DNA conformations in real time, this technique enables a refined characterization of DNA–protein interactions. To increase the output of this powerful but time-consuming single-molecule assay, we have developed a biochip for the simultaneous acquisition of data from more than 500 single DNA molecules. The controlled positioning of individual DNA molecules is achieved by self-assembly on nanoscale arrays fabricated through a standard microcontact printing method. We demonstrate the capacity of our biochip to study biological processes by applying our method to explore the enzymatic activity of the T7 bacteriophage exonuclease. Our single molecule observations shed new light on its behaviour that had only been examined in bulk assays previously and, more specifically, on its processivity.
    Keywords: Protein-nucleic acid interaction
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  • 17
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    Identification of a binding motif specific to HNF4 by comparative analysis of multiple nuclear receptors (2012)
    Oxford University Press
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    Publication Date: 2012-06-28
    Description: Nuclear receptors (NRs) regulate gene expression by binding specific DNA sequences consisting of AG[G/T]TCA or AGAACA half site motifs in a variety of configurations. However, those motifs/configurations alone do not adequately explain the diversity of NR function in vivo . Here, a systematic examination of DNA binding specificity by protein-binding microarrays (PBMs) of three closely related human NRs—HNF4α, retinoid X receptor alpha (RXRα) and COUPTF2—reveals an HNF4-specific binding motif (H4-SBM), xxxxCAAAGTCCA, as well as a previously unrecognized polarity in the classical DR1 motif (AGGTCAxAGGTCA) for HNF4α, RXRα and COUPTF2 homodimers. ChIP-seq data indicate that the H4-SBM is uniquely bound by HNF4α but not 10 other NRs in vivo , while NRs PXR, FXRα, Rev-Erbα appear to bind adjacent to H4-SBMs. HNF4-specific DNA recognition and transactivation are mediated by residues Asp69 and Arg76 in the DNA-binding domain; this combination of amino acids is unique to HNF4 among all human NRs. Expression profiling and ChIP data predict ~100 new human HNF4α target genes with an H4-SBM site, including several Co-enzyme A-related genes and genes with links to disease. These results provide important new insights into NR DNA binding.
    Keywords: Protein-nucleic acid interaction
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  • 18
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    Defining the functional footprint for recognition and repair of deaminated DNA (2012)
    Oxford University Press
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    Publication Date: 2012-12-14
    Description: Spontaneous deamination of DNA is mutagenic, if it is not repaired by the base excision repair (BER) pathway. Crystallographic data suggest that each BER enzyme has a compact DNA binding site. However, these structures lack information about poorly ordered termini, and the energetic contributions of specific protein–DNA contacts cannot be inferred. Furthermore, these structures do not reveal how DNA repair intermediates are passed between enzyme active sites. We used a functional footprinting approach to define the binding sites of the first two enzymes of the human BER pathway for the repair of deaminated purines, alkyladenine DNA glycosylase (AAG) and AP endonuclease (APE1). Although the functional footprint for full-length AAG is explained by crystal structures of truncated AAG, the footprint for full-length APE1 indicates a much larger binding site than is observed in crystal structures. AAG turnover is stimulated in the presence of APE1, indicating rapid exchange of AAG and APE1 at the abasic site produced by the AAG reaction. The coordinated reaction does not require an extended footprint, suggesting that each enzyme engages the site independently. Functional footprinting provides unique information relative to traditional footprinting approaches and is generally applicable to any DNA modifying enzyme or system of enzymes.
    Keywords: Protein-nucleic acid interaction
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  • 19
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    A rapid method for assessing the RNA-binding potential of a protein (2012)
    Oxford University Press
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    Publication Date: 2012-08-08
    Description: In recent years, evidence has emerged for the existence of many diverse types of RNA, which play roles in a wide range of biological processes in all kingdoms of life. These molecules generally do not, however, act in isolation, and identifying which proteins partner with RNA is a major challenge. Many methods, in vivo and in vitro , have been used to address this question, including combinatorial or high-throughput approaches, such as systematic evolution of ligands, cross-linking and immunoprecipitation and RNA immunoprecipitation combined with deep sequencing. However, most of these methods are not trivial to pursue and often require substantial optimization before results can be achieved. Here, we demonstrate a simple technique that allows one to screen proteins for RNA-binding properties in a gel-shift experiment and can be easily implemented in any laboratory. This assay should be a useful first-pass tool for assessing whether a protein has RNA- or DNA-binding properties, prior to committing resources to more complex procedures.
    Keywords: Protein-nucleic acid interaction
    Print ISSN: 0305-1048
    Electronic ISSN: 1362-4962
    Topics: Biology
    Published by Oxford University Press
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  • 20
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    Unbiased proteomic analysis of proteins interacting with the HIV-1 5'LTR sequence: role of the transcription factor Meis (2012)
    Oxford University Press
    Details
    Publication Date: 2012-11-25
    Description: To depict the largest picture of a core promoter interactome, we developed a one-step DNA-affinity capture method coupled with an improved mass spectrometry analysis process focused on the identification of low abundance proteins. As a proof of concept, this method was developed through the analysis of 230 bp contained in the 5'long terminal repeat (LTR) of the human immunodeficiency virus 1 (HIV-1). Beside many expected interactions, many new transcriptional regulators were identified, either transcription factors (TFs) or co-regulators, which interact directly or indirectly with the HIV-1 5'LTR. Among them, the homeodomain-containing TF myeloid ectopic viral integration site was confirmed to functionally interact with a specific binding site in the HIV-1 5'LTR and to act as a transcriptional repressor, probably through recruitment of the repressive Sin3A complex. This powerful and validated DNA-affinity approach could also be used as an efficient screening tool to identify a large set of proteins that physically interact, directly or indirectly, with a DNA sequence of interest. Combined with an in silico analysis of the DNA sequence of interest, this approach provides a powerful approach to select the interacting candidates to validate functionally by classical approaches.
    Keywords: Protein-nucleic acid interaction
    Print ISSN: 0305-1048
    Electronic ISSN: 1362-4962
    Topics: Biology
    Published by Oxford University Press
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  • 21
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    Vein development during folding in the upper brittle crust: The case of tourmaline-rich veins of eastern Elba Island, northern Tyrrhenian Sea, Italy (2012)
    Elsevier
    Details
    Publication Date: 2017-04-04
    Description: Detailed structural analysis of tourmaline-rich veins hosted in the contact aureole of the ∼6 Ma Porto Azzurro granite in southeastern Elba Island, northern Tyrrhenian Sea is presented. Using geometric features of the veins, the physical conditions at the time of vein formation are estimated, namely the stress ratio (Φ = (σ2 − σ3)/(σ1 − σ3)), driving stress ratio (R′ = (Pf − σ3)/(σ1 − σ3)) and fluid overpressure (ΔPo = Pf − σ3). Two vein sets (A veins and B veins) have been recognized based on orientation and thickness distributions and infilling material. Analysis of vein pole distributions indicates Φ = 0.57 and R′ = 0.24 for the A veins and Φ = 0.58 and R′ = 0.47 for the B veins, and fluid pressures less than the intermediate stress magnitude. Analysis of geometric features of the veins gives estimated fluid overpressures of between ∼16 MPa (A veins) and ∼32 MPa (B veins). We propose a model for the tectonic environment of vein development, in which formation of secondary permeability in the deforming thermal aureole of the Porto Azzurro pluton was controlled by ongoing development of fracture systems in the hinge zone of a regional NNW–SSE trending fold that favored transport and localization of hydrothermal fluids.
    Description: Published
    Description: 1509-1522
    Description: 3.2. Tettonica attiva
    Description: 3.3. Geodinamica e struttura dell'interno della Terra
    Description: JCR Journal
    Description: reserved
    Keywords: Thermal aureole ; Upper crust ; Deformation ; Fluid circulation ; Northern Apennines ; Elba Island ; 04. Solid Earth::04.04. Geology::04.04.09. Structural geology ; 04. Solid Earth::04.07. Tectonophysics::04.07.02. Geodynamics ; 04. Solid Earth::04.07. Tectonophysics::04.07.07. Tectonics
    Repository Name: Istituto Nazionale di Geofisica e Vulcanologia (INGV)
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  • 22
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    Magma chambers emplaced in carbonate substrate: petrogenesis of skarn and cumulate rocks and implication on CO2-degassing in volcanic areas (2012)
    Oxford University Press
    Details
    Publication Date: 2017-04-04
    Description: Crystal-rich lithic clasts occurring in volcanic deposits are key tools to understand processes of storage, cooling, and fractionation of magmas in pre-eruptive volcanic systems. These clasts, indeed, represent snapshots of the magma-chamber/host-rock interface before eruptions and provide information on crystallization, differentiation, and degrees of interaction between magma and wall-rocks. In this study, with the aim to shed light on magma-carbonate interaction and CO2 emission in volcanic areas, we focused on the petrology of cumulate and skarn rocks by using as case study a suite of mafic and calcite-bearing lithic clasts from the Colli Albani Volcanic District. By means of phase relations, bulk rock chemistry, phase compositions, and stable isotope data we have recognized different types of cumulates and skarns. Cumulates containing either clinopyroxene±olivine associated with Cr-bearing spinel or glass+phlogopite have been divided in primitive and differentiated, respectively. Primitive cumulates originate at the interface between a relatively primitive magma and carbonate-bearing rocks and show evidences of olivine instability (i.e. heteradcumulate texture) due to carbonate assimilation. Differentiated cumulates, characterized by Ca-rich olivines, phlogopite, and glass containing calcite, form from a differentiated magma in a system open to CaO-contamination. Skarns has been divided in exoskarns, characterized by xenomorphic texture and abundant calcite, and endoskarns, characterized by hypidiomorphic texture, Ca-Tschermak-rich mineral phases, and interstitial glass. Exoskarns formed by means of solid state reactions in a dolostone protolith whereas endoskarns crystallized at subliquidus temperature from a silicate melt that experienced exoskarns assimilation. Our study evidences that magma-carbonate interaction can not be considered a one step process exhausting just after the formation of skarn shells. Magma and carbonate rocks, when in contact, continuously interact leading to the formation of exoskarns, endoskarns, cumulates (primitive and differentiated ones), and differentiated melts. Finally, by means of oxygen and carbon isotope compositions of calcite in equilibrium with skarns, we demonstrate that carbonate assimilation represents a source of massive CO2 degassing mechanism due to the consumption of calcite and removing of CO2 during the decarbonation process.
    Description: Sapienza Universita' di Roma INGV-DPC [Project V 3.1, Colli Albani].
    Description: Published
    Description: 2307-2332
    Description: 2.3. TTC - Laboratori di chimica e fisica delle rocce
    Description: JCR Journal
    Description: reserved
    Keywords: magma/carbonate interaction ; CO2 degassing ; c umulate and skarn ; Colli Albani ; 04. Solid Earth::04.04. Geology::04.04.05. Mineralogy and petrology
    Repository Name: Istituto Nazionale di Geofisica e Vulcanologia (INGV)
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  • 23
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    The deformation offshore of Mount Etna as imaged by multichannel seismic reflection profiles (2012)
    Elsevier
    Details
    Publication Date: 2017-04-04
    Description: Despite the clear evidence of active flank dynamics that is affecting the eastern side of Mount Etna, the contribution of tectonic processes has not been yet understood. So far, the various models proposed to explain the observed flank deformation have been based on onshore structural data, coming from the volcanic edifice. The Ionian offshore of Mount Etna has been only recently investigated using multichannel seismic profiles, and offers the opportunity to image the structural features of the substrate of the unstable flank of the volcano. This contribution aims at describing the deformation located offshore Mount Etna using multichannel seismic profiles recently acquired during three seismic surveys. The onshore flank deformation of Mount Etna appears to be laterally confined by two tectonic guidelines, trending roughly E–W, located to the north and south of the deforming flank; the northern guideline, in particular, takes the surface expression of a sharp fault (Pernicana Fault). Though often assumed that these boundary structures continue offshore as linear features, connected to a frontal thrust ramp, the occurrence of this simple offshore structural system has not been imaged. In fact, seismic data show a remarkable degree of structural complexity offshore Mount Etna. The Pernicana Fault, for instance, is not continuing offshore as a sharp feature; rather, the deformation is expressed as ENE–WSW folds located very close to the coastline. It is possible that these tectonic structures might have affected the offshore of Mount Etna before the Pernicana Fault system was developed, less than 15 ka ago. The southern guideline of the collapsing eastern flank of the volcano is poorly expressed onshore, and does not show up offshore; in fact, seismic data indicate that the Catania canyon, a remarkable E–W-trending feature, does not reflect a tectonic control. Seismic interpretation also shows the occurrence of a structural high located just offshore the edifice of Mount Etna. Whereas a complex deformation affects the boundary of this offshore bulge, it shows only limited internal deformation. Part of the topography of the offshore bulge pre-existed the constructional phase of Mount Etna, being an extension of the Hyblean Plateau. Only in the northern part, the bulge is a recent tectonic feature, being composed by Plio-Quaternary strata that were folded before and during the building of Mount Etna. The offshore bulge is bounded by a thrust fault that can be related to the intrusion of the large-scale magmatic body below Mount Etna.
    Description: Published
    Description: 50-64
    Description: 3.2. Tettonica attiva
    Description: 3.3. Geodinamica e struttura dell'interno della Terra
    Description: 3.5. Geologia e storia dei vulcani ed evoluzione dei magmi
    Description: JCR Journal
    Description: restricted
    Keywords: Mount Etna offshore ; Volcano flank instability ; Active tectonics ; Multichannel reflection seismics ; Intrusive body ; 04. Solid Earth::04.04. Geology::04.04.04. Marine geology ; 04. Solid Earth::04.07. Tectonophysics::04.07.02. Geodynamics ; 04. Solid Earth::04.07. Tectonophysics::04.07.07. Tectonics ; 04. Solid Earth::04.08. Volcanology::04.08.02. Experimental volcanism
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  • 24
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    Fault architecture in the Main Ethiopian Rift and comparison with experimental models: Implications for rift evolution and Nubia–Somalia kinematics (2012)
    Elsevier
    Details
    Publication Date: 2020-05-28
    Description: The Main Ethiopian Rift (MER) offers a complete record of the time–space evolution of a continental rift. We have characterized the brittle deformation in different rift sectors through the statistical analysis of a new database of faults obtained from the integration between satellite images and digital elevation models, and implemented with field controls. This analysis has been compared with the results of lithospheric-scale analogue models reproducing the kinematical conditions of orthogonal and oblique rifting. Integration of these approaches suggests substantial differences in fault architecture in the different rift sectors that in turn reflect an along-axis variation of the rift development and southward decrease in rift evolution. The northernmost MER sector is in a mature stage of incipient continental rupture, with deformation localised within the rift floor along discrete tectono-magmatic segments and almost inactive boundary faults. The central MER sector records a transitional stage in which migration of deformation from boundary faults to faults internal to the rift valley is in an incipient phase. The southernmost MER sector is instead in an early continental stage, with the largest part of deformation being accommodated by boundary faults and almost absent internal faults. The MER thus records along its axis the typical evolution of continental rifting, from fault-dominated rift morphology in the early stages of extension toward magma-dominated extension during break-up. The extrapolation of modelling results suggests that a variable rift obliquity contributes to the observed along-axis variations in rift architecture and evolutionary stage, being oblique rifting conditions controlling the MER evolution since its birth in the Late Miocene in relation to a constant post ca. 11 Ma ~ N100°E Nubia–Somalia motion.
    Description: Published
    Description: 479-492
    Description: 3.2. Tettonica attiva
    Description: 3.3. Geodinamica e struttura dell'interno della Terra
    Description: JCR Journal
    Description: reserved
    Keywords: continental rifting ; East African Rift ; Main Ethiopian Rift ; rift kinematics ; plate kinematics ; 04. Solid Earth::04.04. Geology::04.04.09. Structural geology ; 04. Solid Earth::04.07. Tectonophysics::04.07.02. Geodynamics ; 04. Solid Earth::04.07. Tectonophysics::04.07.07. Tectonics
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  • 25
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    UPb and 40Ar39Ar geochronology of Palaeozoic units in the northern Apennines: determining protolith age and alpine evolution using the Calamita Schist and Ortano Porphyroid (2012)
    Wiley
    Details
    Publication Date: 2017-04-04
    Description: In the northern Apennines, the Palaeozoic basement involved in the Late Oligocene–Middle Miocene nappe stack contains metamorphic units for which hypothetical ages have been assigned on the basis of lithological correlations with the Palaeozoic formations of the Variscan chain in Sardinia. This uncertainty concerning the age poses limitations to reconstructing the Palaeozoic stratigraphy, defining the Alpine and pre-Alpine histories and correlations with other domains of the Variscan chain. We present the UPb age of detrital zircon and the 40Ar39Ar age of metamorphic muscovite for the Calamita Schist and Ortano Porphyroid, two metamorphic units of undetermined Palaeozoic age cropping out in the eastern Elba Island. The radioisotopic data allows us to: (i) define the Early Carboniferous and Middle Ordovician ages for the Calamita Schist and Ortano Porphyroid, respectively, as well as their derivation (flysch deposit and magmatic rocks); (ii) pose some constraints concerning their alpine tectonic and metamorphic histories. These new data generate a more precise reconstruction of the Palaeozoic sequence in the northern Apennines, and they document that the Palaeozoic basement involved in the alpine deformation underwent internal stacking with an inversion of the original sequence. Copyright © 2010 John Wiley & Sons, Ltd.
    Description: Published
    Description: 288-310
    Description: 3.2. Tettonica attiva
    Description: 3.3. Geodinamica e struttura dell'interno della Terra
    Description: JCR Journal
    Description: reserved
    Keywords: northern Apennines ; Palaeozoic basement ; U-Pb zircon ; 40Ar-39Ar muscovite ; 04. Solid Earth::04.04. Geology::04.04.02. Geochronology ; 04. Solid Earth::04.04. Geology::04.04.09. Structural geology ; 04. Solid Earth::04.07. Tectonophysics::04.07.07. Tectonics
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  • 26
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    Dynamic plumbing system beneath volcanoes revealed by kinetic modeling, and the connection to monitoring data: An example from Mt. Etna (2012)
    Elsevier
    Details
    Publication Date: 2023-01-27
    Description: Our ability to monitor volcanoes (using seismic signals, ground deformation, gas fluxes, or other ground and satellite based observations) as well as our understanding of melt reservoirs that feed eruptions have evolved tremendously in recent years. The complex plumbing systems that are thought to feed eruptions are, however, difficult to relate to the monitoring signals. Here we show that the record preserved in compositional zoning of erupted minerals may be used to reconstruct sections of the plumbing system. Kinetic modeling of such zoning can yield information on the residence time of magma in different segments of the plumbing systems. This allows a more nuanced evaluation of the link between observed monitoring signals or eruption styles and the magmatic processes and movement of batches of melts at depth. The approach is illustrated through a study of the compositional zoning recorded in olivine crystals from the 1991–1993 SE-flank eruption products of Mt. Etna (Sicily). The zoning patterns in crystals reveal that the plumbing system of the volcano consisted of at least three different magmatic environments between which magma was transported and mixed in the year or two preceding the start of eruption. Quantification of this history indicates that two main pathways of melt migration and three timescales dominated the dynamics of the system. Combination of this information with the timing of observation of various monitoring signals allows a reconstruction of the dynamic evolution of this section of the plumbing system during the early stages of the 1991–1993 eruption. It is seen, for example, how the migration of melt through the same sections of the plumbing system can cause pre-eruptive triggering, enhance Strombolian activity, and through the ensuing eruption cleanse and flush the plumbing system. Different kinds of mixing occur simultaneously at different sections of the plumbing system on different timescales (a few days up to two years).
    Description: Published
    Description: 11-22
    Description: 1.5. TTC - Sorveglianza dell'attività eruttiva dei vulcani
    Description: 2.3. TTC - Laboratori di chimica e fisica delle rocce
    Description: 3.5. Geologia e storia dei vulcani ed evoluzione dei magmi
    Description: JCR Journal
    Description: reserved
    Keywords: Etna ; plumbing system ; olivine ; zoning ; timescales ; monitoring ; 04. Solid Earth::04.04. Geology::04.04.05. Mineralogy and petrology ; 04. Solid Earth::04.08. Volcanology::04.08.03. Magmas ; 04. Solid Earth::04.08. Volcanology::04.08.05. Volcanic rocks
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  • 27
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    Self-similar clustering of cinder cones and crust thickness in the Michoacan–Guanajuato and Sierra de Chichinautzin volcanic fields, Trans-Mexican Volcanic Belt (2011)
    Elsevier
    Details
    Publication Date: 2021-04-20
    Description: The spatial clustering of basaltic vents in monogenetic volcanic fields has been used as a proxy for crustal thickness in extensional and back-arc tectonic settings. The basaltic vents have a fractal clustered distribution (self-similar clustering) described by a power-law. The power-law is defined over a range, the size range of the distribution, of values (in this case the vents' separation) delimited by a lower and an upper cut-offs. Here we apply the fractal clustering analysis to the two largest monogenetic volcanic fields of the Trans-Mexican Volcanic Belt (TMVB), a continental arc built on different crustal terranes. The Michoacan–Guanajuato volcanic field (MGVF), located in the central-western TMVB, includes over 1000 vents of late Pliocene to Quaternary age, built on attenuated crust of Mesozoic to Tertiary age. The Sierra de Chichinautzin volcanic field (SCVF), in the central-eastern TMVB, is composed of ~ 220 Late Pleistocene to Holocene vents laying above thicker crust of Precambrian to Tertiary age. Monogenetic vents in both volcanic fields show self-similar clustering with fractal exponent D = 1.67 in the range 1.3–38 km (MGVF) and D = 1.56 in the range 1.5–32 km (SCVF). The upper cut-off (Uco) for the power-law distribution of the MGVF well fits the crustal thickness below the volcanic field as derived from independent geophysical data. The Uco value of SCVF indicates a crust thickness of about 32 km, this value is in agreement with new geophysical data that indicate magma underplating the crust beneath the volcanic field area.
    Description: Published
    Description: 55-64
    Description: 1.10. TTC - Telerilevamento
    Description: 3.2. Tettonica attiva
    Description: 3.3. Geodinamica e struttura dell'interno della Terra
    Description: JCR Journal
    Description: reserved
    Keywords: Volcanic fields ; Tectonic ; Vent distribution ; Crust thickness ; Mexico ; 04. Solid Earth::04.04. Geology::04.04.09. Structural geology ; 04. Solid Earth::04.07. Tectonophysics::04.07.05. Stress ; 04. Solid Earth::04.07. Tectonophysics::04.07.07. Tectonics
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  • 28
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    Strain accumulation across the Messina Straits and kinematics of Sicily and Calabria from GPS data and dislocation modeling (2011)
    Elsevier
    Details
    Publication Date: 2020-12-03
    Description: We use Global Positioning System (GPS) velocities and dislocation modeling to investigate the rate and nature of interseismic strain accumulation in the area affected by the 1908 Mw 7.1 Messina earthquake (southern Italy) within the framework of the complex central Mediterranean microplate kinematics. Our data confirm a change in the velocity trends between Sicily and Calabria, moving from NNW-ward to NE- ward with respect to Eurasia, and detail a fan-like pattern across the Messina Straits where maximum extensional strain rates are ~65 nanostrains/yr. Extension normal to the coast of northern Sicily is consistent with the presence of SW–NE trending normal faults. Half-space dislocation models of the GPS velocities are used to infer the slip-rates and geometric fault parameters of the fault zone that ruptured in the Messina − 1.3 earthquake. The inversion, and the bootstrap analysis of model uncertainties, finds optimal values of 3. 5 + 2.0 − 0.2− 0.7 and 1.6 + 0.3 mm/yr for the dip–slip and strike–slip components, respectively, along a 30 + 1.1° SE-ward dipping normal fault, locked above 7.6−2.9 km depth. By developing a regional elastic block model that + 4.6 accounts for both crustal block rotations and strain loading at block-bounding faults, and adopting two different competing models for the Ionian–Calabria convergence rates, we show that the measured velocity gradient across the Messina Straits may be significantly affected by the elastic strain contribution from other nearby faults. In particular, when considering the contribution of the possibly locked Calabrian subduction interface onto the observed velocity gradients in NE-Sicily and western Calabria, we find that this longer wavelength signal can be presently super-imposed on the observed velocity gradients in NE-Sicily and Calabria. The inferred slip-rate on the Messina Fault is significantly impacted by elastic strain from the subduction thrust. By varying the locking of the subduction thrust fault, in fact, the Messina Fault slip-rate varies from 0 to 9 mm/yr.
    Description: Published
    Description: 347-360
    Description: 1.9. Rete GPS nazionale
    Description: 3.2. Tettonica attiva
    Description: JCR Journal
    Description: open
    Keywords: Messina Straits ; Global Positioning System ; strain accumulation ; plate kinematics ; dislocation modeling ; 04. Solid Earth::04.03. Geodesy::04.03.01. Crustal deformations ; 04. Solid Earth::04.03. Geodesy::04.03.06. Measurements and monitoring ; 04. Solid Earth::04.03. Geodesy::04.03.07. Satellite geodesy ; 04. Solid Earth::04.06. Seismology::04.06.01. Earthquake faults: properties and evolution ; 04. Solid Earth::04.06. Seismology::04.06.11. Seismic risk ; 04. Solid Earth::04.07. Tectonophysics::04.07.04. Plate boundaries, motion, and tectonics ; 04. Solid Earth::04.07. Tectonophysics::04.07.06. Subduction related processes ; 04. Solid Earth::04.07. Tectonophysics::04.07.07. Tectonics
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  • 29
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    Fluid circulation in the upper brittle crust: Thickness distribution, hydraulic transmissivity fluid inclusion and isotopic data of veins hosted in the Oligocene sandstones of the Macigno Formation in southern Tuscany, Italy (2011)
    Elsevier
    Details
    Publication Date: 2020-11-30
    Description: We present structural analysis, fluid inclusion data on calcite and quartz, and isotopic composition of calcite forming veins occurring in the upper crustal level and hosted in Oligocene sandstone in southern Tuscany (Italy). The veins have been analysed in two sites few kilometres apart, along well-exposed coastal cliffs and in an abandoned quarry. These two sites were at a different depths at the time of the vein formation with a Δh ~ 100 m. Structural analysis of veins provided estimations of stress ratio (Φ = (σ2 − σ3)/(σ1 − σ3)), driving stress ratio (R′ = (Pf − σ3)/(σ1 − σ3)) and fluid overpressure (ΔPo = Pf − σ3) at the time of vein formation. The estimated ΔPo is in the range of 42–103 MPa, Φ = 0.24 and R′ = 0.45, indicating that fluid pressure was higher than the intermediate principal stress at the time of veins formation. The veins' thickness (t) shows a clear power-law distribution (D = 1.8835 and R2 = 0.9762) in the lowermost site (coast) and a negative exponential distribution (a = 0.6943 and R2 = 0.9921) in the uppermost site (abandoned quarry). The vein thickness distributions have been used to compute the average transmissivity of the veins in the two sites. The computed transmissivity for the vein formation is ~ 10−4 m2 s−1, with higher values attained by the veins having negative exponential thickness distribution. Fluid inclusions studies highlighted that in both calcite and quartz, water-rich inclusions, with salinities of 2.2–4.3 wt.% NaCl equiv., and methane-rich inclusions were coevally trapped during fluid un-mixing processes. Thermogenic origin, from thermal maturation of organic matter present in the Macigno Formation, is proposed for methane. Whereas, the similarity between the δ18O (from 14.9 to 17.4‰) and δ13C (from −0.4 to −2.4‰) data of representative calcite veins and the isotopic composition (δ18O: 16.1‰, δ13C: −1.0‰) of host-rock carbonate component, indicates that the fluid which formed calcite was in isotopic equilibrium with the carbonates present in the Oligocene sandstones. The calculated pressure–temperature conditions during the formation of these inclusions are prevalently within the 40–145 MPa and 160–260 °C ranges. The highest pressure values approximate the lithostatic pressure (~ 120 MPa) computed from geological data and are coherent with a geothermal gradient ranges of 35–45 °C/km. Whereas, the lower pressure values are comparable with hydrostatic pressure conditions. The pressure range indicated by fluid inclusion data is also comparable with the fluid pressure estimated from structural analysis. The considerable pressure range can be related to pressure cycling between lithostatic and hydrostatic conditions as a consequence of fault-valve actions and rock fracturing with subsequent pressure recover due to self-sealing process.
    Description: Published
    Description: 118-138
    Description: 3.2. Tettonica attiva
    Description: 3.3. Geodinamica e struttura dell'interno della Terra
    Description: JCR Journal
    Description: reserved
    Keywords: Vein systems ; Fluid type ; Fluid pressure ; Fluid inclusions ; Upper crust ; Tuscany ; 04. Solid Earth::04.04. Geology::04.04.09. Structural geology ; 04. Solid Earth::04.04. Geology::04.04.12. Fluid Geochemistry ; 04. Solid Earth::04.07. Tectonophysics::04.07.07. Tectonics
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  • 30
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    Societal need for improved understanding of climate change, anthropogenic impacts, and geo-hazard warning drive development of ocean observatories in European Seas (2011)
    Elsevier
    Details
    Publication Date: 2017-04-04
    Description: Society’s needs for a network of in situ ocean observing systems cross many areas of earth and marine science. Here we review the science themes that benefit from data supplied from ocean observatories. Understanding from existing studies is fragmented to the extent that it lacks the coherent long-term monitoring needed to address questions at the scales essential to understand climate change and improve geo-hazard early warning. Data sets from the deep sea are particularly rare with long-term data available from only a few locations worldwide. These science areas have impacts on societal health and well-being and our awareness of ocean function in a shifting climate. Substantial efforts are underway to realise a network of open-ocean observatories around European Seas that will operate over multiple decades. Some systems are already collecting high-resolution data from surface, water column, seafloor, and sub-seafloor sensors linked to shore by satellite or cable connection in real or near-real time, along with samples and other data collected in a delayed mode. We expect that such observatories will contribute to answering major ocean science questions including: How can monitoring of factors such as seismic activity, pore fluid chemistry and pressure, and gas hydrate stability improve seismic, slope failure, and tsunami warning? What aspects of physical oceanography, biogeochemical cycling, and ecosystems will be most sensitive to climatic and anthropogenic change? What are natural versus anthropogenic changes? Most fundamentally, how are marine processes that occur at differing scales related? The development of ocean observatories provides a substantial opportunity for ocean science to evolve in Europe. Here we also describe some basic attributes of network design. Observatory networks provide the means to coordinate and integrate the collection of standardised data capable of bridging measurement scales across a dispersed area in European Seas adding needed certainty to estimates of future oceanic conditions. Observatory data can be analysed along with other data such as those from satellites, drifting floats, autonomous underwater vehicles, model analysis, and the known distribution and abundances of marine fauna in order to address some of the questions posed above. Standardised methods for information management are also becoming established to ensure better accessibility and traceability of these data sets and ultimately to increase their use for societal benefit. The connection of ocean observatory effort into larger frameworks including the Global Earth Observation System of Systems (GEOSS) and the Global Monitoring of Environment and Security (GMES) is integral to its success. It is in a greater integrated framework that the full potential of the component systems will be realised.
    Description: Published
    Description: 1-33
    Description: 3.7. Dinamica del clima e dell'oceano
    Description: JCR Journal
    Description: reserved
    Keywords: Seafloor and water columnobservatories ; 01. Atmosphere::01.01. Atmosphere::01.01.02. Climate ; 01. Atmosphere::01.01. Atmosphere::01.01.04. Processes and Dynamics ; 01. Atmosphere::01.01. Atmosphere::01.01.08. Instruments and techniques ; 03. Hydrosphere::03.01. General::03.01.03. Global climate models ; 03. Hydrosphere::03.01. General::03.01.07. Physical and biogeochemical interactions ; 03. Hydrosphere::03.01. General::03.01.08. Instruments and techniques ; 03. Hydrosphere::03.03. Physical::03.03.01. Air/water/earth interactions ; 03. Hydrosphere::03.03. Physical::03.03.02. General circulation ; 03. Hydrosphere::03.03. Physical::03.03.03. Interannual-to-decadal ocean variability ; 03. Hydrosphere::03.03. Physical::03.03.05. Instruments and techniques ; 03. Hydrosphere::03.04. Chemical and biological::03.04.01. Biogeochemical cycles ; 03. Hydrosphere::03.04. Chemical and biological::03.04.02. Carbon cycling ; 03. Hydrosphere::03.04. Chemical and biological::03.04.03. Chemistry of waters ; 03. Hydrosphere::03.04. Chemical and biological::03.04.04. Ecosystems ; 03. Hydrosphere::03.04. Chemical and biological::03.04.05. Gases ; 03. Hydrosphere::03.04. Chemical and biological::03.04.06. Hydrothermal systems ; 03. Hydrosphere::03.04. Chemical and biological::03.04.08. Instruments and techniques ; 04. Solid Earth::04.01. Earth Interior::04.01.02. Geological and geophysical evidences of deep processes ; 04. Solid Earth::04.04. Geology::04.04.04. Marine geology ; 04. Solid Earth::04.04. Geology::04.04.11. Instruments and techniques ; 04. Solid Earth::04.04. Geology::04.04.12. Fluid Geochemistry ; 04. Solid Earth::04.05. Geomagnetism::04.05.05. Main geomagnetic field ; 04. Solid Earth::04.05. Geomagnetism::04.05.08. Instruments and techniques ; 04. Solid Earth::04.06. Seismology::04.06.06. Surveys, measurements, and monitoring ; 04. Solid Earth::04.06. Seismology::04.06.07. Tomography and anisotropy ; 04. Solid Earth::04.06. Seismology::04.06.08. Volcano seismology ; 04. Solid Earth::04.06. Seismology::04.06.10. Instruments and techniques ; 04. Solid Earth::04.07. Tectonophysics::04.07.02. Geodynamics ; 04. Solid Earth::04.07. Tectonophysics::04.07.03. Heat generation and transport ; 04. Solid Earth::04.07. Tectonophysics::04.07.04. Plate boundaries, motion, and tectonics ; 04. Solid Earth::04.07. Tectonophysics::04.07.07. Tectonics ; 04. Solid Earth::04.08. Volcanology::04.08.01. Gases ; 04. Solid Earth::04.08. Volcanology::04.08.02. Experimental volcanism ; 04. Solid Earth::04.08. Volcanology::04.08.06. Volcano monitoring ; 04. Solid Earth::04.08. Volcanology::04.08.07. Instruments and techniques ; 05. General::05.01. Computational geophysics::05.01.01. Data processing ; 05. General::05.02. Data dissemination::05.02.99. General or miscellaneous ; 05. General::05.02. Data dissemination::05.02.01. Geochemical data ; 05. General::05.02. Data dissemination::05.02.02. Seismological data ; 05. General::05.02. Data dissemination::05.02.03. Volcanic eruptions ; 05. General::05.02. Data dissemination::05.02.04. Hydrogeological data ; 05. General::05.08. Risk::05.08.01. Environmental risk ; 05. General::05.08. Risk::05.08.02. Hydrogeological risk
    Repository Name: Istituto Nazionale di Geofisica e Vulcanologia (INGV)
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  • 31
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    Experimental solidification of an andesitic melt by cooling (2011)
    Elsevier
    Details
    Publication Date: 2017-04-04
    Description: Solidification experiments at (a) five different cooling rates (25, 12.5, 3, 0.5 and 0.125 °C/min) between 1300 and 800 °C, and (b) variable quenching temperatures (1100, 1000, 900 and 800 °C) at a fixed cooling rate of 0.5 °C/min were performed on an andesitic melt (SiO2=58.52 wt.% and Na2O+K2O=4.43 wt.%) at air conditions from high superheating temperature. The results show that simultaneous and duplicated experiments with Pt-wire or Pt-capsule produce identical run-products. Preferential nucleation on Ptcontainers or bubbles is lacking. Plagioclase and Fe–Ti oxide crystals nucleate firstly from the melt. Clinopyroxene crystals form only at lower cooling rates (0.5 and 0.125 °C/min) and quenching temperatures (900 and 800 °C). At higher cooling rates (25, 12.5 and 3 °C/min) and quenching temperature (1100 °C), plagioclase and Fe–Ti oxide crystals are embedded in a glassy matrix; by contrast, at lower cooling rates (0.5 and 0.125 °C/min) and below 1100 °C they form an intergrowth texture. The crystallization of plagioclase and Fe–Ti oxide starts homogeneously and then proceeds by heterogeneous nucleation. The crystal size distribution (CSD) analysis of plagioclase shows that crystal coarsening increases with decreasing cooling rate and quenching temperature. At the same time, the average growth rate of plagioclases decreases from 2.1×10−6 cm/s (25 °C/min) to 5.7×10−8 cm/s (0.125 °C/min) and crystals tend to be more equant in habit. Plagioclases and Fe–Ti oxides depart from their equilibrium compositions with increasing cooling rate; plagioclases shift from labradorite–andesine to anorthite–bytownite. Therefore, kinetic effects due to cooling significantly change the plagioclase composition with remarkable petrological implications for the solidification of andesitic lavas and dikes. The glass-forming ability (GFA) of the andesitic melt has been also quantified in a critical cooling rate (Rc) of ~37 °C/min. This value is higher than those measured for latitic (Rc ~1 °C/min) and trachytic (Rcb0.125 °C/min) liquids demonstrating that little changes of melt composition are able to significantly shift the initial nucleation behavior of magmas and the following solidification paths.
    Description: Published
    Description: 261–273
    Description: 2.3. TTC - Laboratori di chimica e fisica delle rocce
    Description: JCR Journal
    Description: reserved
    Keywords: Andesitic melt ; Experimental solidification ; 04. Solid Earth::04.04. Geology::04.04.05. Mineralogy and petrology
    Repository Name: Istituto Nazionale di Geofisica e Vulcanologia (INGV)
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  • 32
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    Petrology of the most recent ultrapotassic magmas from the Roman Province (Central Italy) (2011)
    Elsevier
    Details
    Publication Date: 2017-04-04
    Description: We report on the newly discovered lava flow that erupted in the Colli Albani Volcanic District, which is the most recent and, geochemically the most peculiar effusive event recognised in the entire ultrapotassic Roman Province (Central Italy). This lava flow is associated with the Monte Due Torri scoria cone, located approximately 5 km south of the Albano hydromagmatic centre (69–36 ka). TheMonte Due Torri scoria cone displays well-preserved morphological characteristics and the 40±7 ka age determined for the associated lava flow indicates that its activity was nearly contemporaneous to the most recent, explosive activity that occurred at the Albano centre from 41 to 36 ka. By comparing chemical and petrological features of the Monte Due Torri lava flow, Albano products, and older products (N69 ka), we show that the youngest Colli Albani eruptions were fed by two new batches of parental magmas that originated in a phlogopite-bearing metasomatised mantle, each one feeding one of the two youngest eruptive cycles (at 69 ka and 41–36 ka). The trace element signature, e.g., very low Pb content, of primitive (MgON3 wt.%) magmas feeding the initiation of the hydromagmatic activity at Albano (69 ka) and the subsequent effusive activity at Monte Due Torri (40 ka) indicates that a magma chamber located in the deep anhydrite-bearing dolomite formation was tapped. However, the polygenic activity, the changes in magma composition, and the variable thermometamorphic clasts occurring in the hydromagmatic deposits (recording variable substrata) suggest, particularly for the Albano eruptive centre, a more complex plumbing system consisting of at least two more magma chambers at a shallower depth, i.e., in the Mesozoic limestone and Pliocene pelite formations. The large amount of stratigraphic, volcanological, and geochemical data collected for the Colli Albani Volcanic District, one of the main districts in the ultrapotassic Roman Province, enable us to contribute insights into the still open debate regarding the temporal variation of the metasomatised mantle source of the Italian potassic magmas. Based on our data, i.e., variation of radiogenic and trace elements over time, we suggest that the observed variation in the mantle source of the ultrapotassic magmas can be related to progressive consumption of the phlogopite component in the metasomatised source rather than the transition from lithosphere- to asthenosphere-derived magmatism and/or the transition from orogenic to anorogenic magmatism.
    Description: Published
    Description: 298-308
    Description: 2.3. TTC - Laboratori di chimica e fisica delle rocce
    Description: JCR Journal
    Description: reserved
    Keywords: ultrapotassic magmas ; metasomatised mantle ; Roman Province ; Colli Albani ; 04. Solid Earth::04.04. Geology::04.04.05. Mineralogy and petrology
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  • 33
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    Plagioclase–melt (dis)equilibrium due to cooling dynamics: Implications for thermometry, barometry and hygrometry (2011)
    Elsevier
    Details
    Publication Date: 2017-04-04
    Description: The compositional variation of plagioclase and the partitioning of major elements between plagioclase and melt have been experimentally measured as a function of the cooling rate. Crystals were grown from a basaltic melt at a pressure of 500 MPa under (i) variable cooling rates of 0.5, 2.1, 3, 9.4, and 15 °C/min from 1250 °C down to 1000 °C, (ii) quenching temperatures of 1025, 1050, 1075, 1090, and 1100 °C at the fixed cooling rate of 0.5 °C/min, and (iii) isothermal temperatures of 1000, 1025, 1050, 1075, 1090, and 1100 °C. Our results show that euhedral, faceted plagioclases form during isothermal and slower cooling experiments exhibiting idiomorphic tabular shapes. In contrast, dendritic shapes are observed from faster cooled charges. As the cooling rate is increased, concentrations of Al+Ca+Fe+Mg increase and Si+Na+K decrease in plagioclase favoring higher An and lower Ab+Or contents. Significant variations of pl–liqKd are also observed by the comparison between isothermal and cooled charges; notably, pl–liqKdAb–An, pl–liqKdCa–Na and pl–liqKdFe–Mg progressively change with increasing cooling rate. Therefore, crystal–melt exchange reactions have the potential to reveal the departure from equilibrium for plagioclase-bearing cooling magmas. Finally, thermometers, barometers, and hygrometers derived through the plagioclase–liquid equilibria have been tested at these non-equilibrium experimental conditions. Since such models are based on assumption of equilibrium, any form of disequilibrium will yield errors. Results show that errors on estimates of temperature, pressure, and melt-water content increase systematically with increasing cooling rate (i.e. disequilibrium condition) depicting monotonic trends towards drastic overestimates. These trends are perfectly correlated with those of pl–liqKdCa–Na, pl–liqKdAb–An, and pl–liqKdFe–Mg, thus demonstrating their ability to test (dis)equilibrium conditions.
    Description: Published
    Description: 221–235
    Description: 2.3. TTC - Laboratori di chimica e fisica delle rocce
    Description: JCR Journal
    Description: reserved
    Keywords: Cooling rate ; Partition coefficients ; Thermometers ; 04. Solid Earth::04.04. Geology::04.04.05. Mineralogy and petrology
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  • 34
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    Cooling history of a dike as revealed by mineral chemistry: A case study from Mt. Etna volcano (2011)
    Elsevier
    Details
    Publication Date: 2017-04-04
    Description: Seven rock samples were systematically collected from innermost to the outermost portion of a dike outcropping at Mt. Etna volcano. Results show that, from dike core-to-rim, plagioclase, clinopyroxene and titanomagnetite show compositional variations due to increasing cooling rate. Plagioclase is progressively enriched in An from innermost to the outermost part of the dike. Similarly, clinopyroxene components En+ CaTs+CaFeTs increase, whereas Di+Hd decrease. The Usp content in titanomagnetite also systematically decrease from dike core-to-rim. Partition coefficients and thermometers based on the crystal-liquid exchange reaction indicate that, due to rapid cooling rates at the dike outer portions, early-formed crystal nuclei do not re-equilibrate with the melt. The chemistry of minerals progressively deviates from that of equilibrium; consequently, from dike core-to-rim, mineral compositions resemble those of high-temperature formation. The chemical variations of clinopyroxene and plagioclase in dike samples mirror those obtained from cooling experiments carried out on alkaline basalts. Accordingly, we used an experimental equation based on clinopyroxene compositional variation as a function of cooling rate to determine the cooling conditions experienced by the crystals during dike emplacement. The estimated cooling rates are comparable to those predicted by thermal modeling based on an explicit finite-difference scheme.
    Description: Published
    Description: 39-52
    Description: 2.3. TTC - Laboratori di chimica e fisica delle rocce
    Description: JCR Journal
    Description: reserved
    Keywords: dike ; clinopyroxene ; 04. Solid Earth::04.04. Geology::04.04.05. Mineralogy and petrology
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  • 35
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    Seismotectonic of Southern Apennines from recent passive seismic experiments (2011)
    Elsevier
    Details
    Publication Date: 2017-04-04
    Description: We used data of local earthquakes collected during two recent passive seismic experiments carried out in southern Italy in order to study the seismotectonic setting of the Lucanian Apennine and the surrounding areas. Based on continuous recordings of the temporary stations we extracted over 15,600 waveforms, which were hand-picked along with those recorded by the permanent stations of the Italian national seismic network obtaining a dense, high-quality dataset of P- and S-arrival times. We examined the seismicity occurring in the period 2001–2008 by relocating 566 out of 1047 recorded events with magnitudes ML ≥1.5 and computing 162 fault-plane solutions. Earthquakes were relocated using a minimum one-dimensional velocity model previously obtained for the region and a Vp/Vs ratio of 1.83. Background seismicity is concentrated within the upper crust (between 5 and 20km of depth) and it is mostly clustered along the Lucanian Apennine chain axis. A significant feature extracted from this study relates to the two E–W trending clusters located in the Potentino and in the Abriola–Pietrapertosa sector (central Lucania region). Hypocentral depths in both clusters are slightly deeper than those observed beneath the Lucanian Apennine. We suggest that these two seismic features are representative of the transition from the inner portion of the chain to the external margin characterized by dextral strike-slip kinematics. In the easternmost part of the study area, below the Bradano foredeep and the Apulia foreland, seismicity is generally deeper and more scattered. The sparse seismicity localized in the Sibari Plain, in the offshore area along the northeastern Calabrian coast and in the Taranto Gulf is also investigated thanks to the new recordings. This seismicity shows hypocenters between 12 and 20km of depth below the Sibari Plain and is deeper (foci between 10 and 35km of depth) in the offshore area of the Taranto Gulf. 102 well-constrained fault-plane solutions, showing predominantly normal and strike-slip character with tensional axes (T-axes) generally NE oriented, were selected for the stress tensor analysis. We investigated stress field orientation inverting focal mechanism belonging to the Lucanian Apennine and the Pollino Range, both areas characterized by a more concentrated background seismicity.
    Description: Published
    Description: 110-124
    Description: 3.2. Tettonica attiva
    Description: 5.7. Consulenze in favore di istituzioni nazionali e attività nell'ambito di trattati internazionali
    Description: JCR Journal
    Description: restricted
    Keywords: Background seismicity ; Passive seismic experiments ; Southern Apennines ; Apulia foreland ; Stress field ; Seismotectonic ; 04. Solid Earth::04.06. Seismology::04.06.01. Earthquake faults: properties and evolution ; 04. Solid Earth::04.06. Seismology::04.06.06. Surveys, measurements, and monitoring ; 04. Solid Earth::04.07. Tectonophysics::04.07.07. Tectonics
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  • 36
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    Graphical interactive generation of gravity and magnetic fields (2011)
    Elsevier
    Details
    Publication Date: 2017-04-04
    Description: This paper presents a MATLAB®- based geopotential field generator called GamField that constructs and visualizes subsurface sources in 3-D space and computes their gravity and magnetic effects. GamField also computes anomaly gradients and remanent magnetization effects. The user inputs Cartesian prisms along with their physical properties to fabricate subsurface sources. Examples illustrating the utility of GamField for synthetic anomaly generation of gravity and magnetic fields are shown. ftp://ftp.ingv.it/pub/alessandro.pignatelli/Pignatelli
    Description: Published
    Description: 567–572
    Description: 3.4. Geomagnetismo
    Description: 3.8. Geofisica per l'ambiente
    Description: 5.7. Consulenze in favore di istituzioni nazionali e attività nell'ambito di trattati internazionali
    Description: JCR Journal
    Description: restricted
    Keywords: Gravity anomalycomputation ; Magnetic anomalycomputation ; MATLAB ; 04. Solid Earth::04.03. Geodesy::04.03.04. Gravity anomalies ; 04. Solid Earth::04.05. Geomagnetism::04.05.04. Magnetic anomalies ; 04. Solid Earth::04.07. Tectonophysics::04.07.07. Tectonics ; 05. General::05.01. Computational geophysics::05.01.05. Algorithms and implementation ; 05. General::05.05. Mathematical geophysics::05.05.99. General or miscellaneous
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  • 37
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    Graphical interactive generation of gravity and magnetic fields (2011)
    Elsevier
    Details
    Publication Date: 2020-02-24
    Description: This paper presents a MATLAB®- based geopotential field generator called GamField that constructs and visualizes subsurface sources in 3-D space and computes their gravity and magnetic effects. GamField also computes anomaly gradients and remanent magnetization effects. The user inputs Cartesian prisms along with their physical properties to fabricate subsurface sources. Examples illustrating the utility of GamField for synthetic anomaly generation of gravity and magnetic fields are shown. ftp://ftp.ingv.it/pub/alessandro.pignatelli/Pignatelli
    Description: In press
    Description: 3.4. Geomagnetismo
    Description: 3.8. Geofisica per l'ambiente
    Description: 5.7. Consulenze in favore di istituzioni nazionali e attività nell'ambito di trattati internazionali
    Description: JCR Journal
    Description: restricted
    Keywords: Gravity anomalycomputation ; Magnetic anomalycomputation ; MATLAB ; 04. Solid Earth::04.03. Geodesy::04.03.04. Gravity anomalies ; 04. Solid Earth::04.05. Geomagnetism::04.05.04. Magnetic anomalies ; 04. Solid Earth::04.07. Tectonophysics::04.07.07. Tectonics ; 05. General::05.01. Computational geophysics::05.01.05. Algorithms and implementation ; 05. General::05.05. Mathematical geophysics::05.05.99. General or miscellaneous
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  • 38
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    Conditions of Magma Storage, Degassing and Ascent at Stromboli: New Insights into the Volcano Plumbing System with Inferences on the Eruptive Dynamics (2011)
    Oxford University Press
    Details
    Publication Date: 2017-04-04
    Description: Stromboli is known for its persistent degassing and rhythmic strombolian activity occasionally punctuated by paroxysmal eruptions. The basaltic pumice and scoria emitted during paroxysms and strombolian activity, respectively, differ in their textures, crystal contents and glass matrix compositions, which testify to distinct conditions of crystallization, degassing and magma ascent. We present here an extensive dataset on major elements and volatiles (CO2, H2O, S and Cl) in olivine-hosted melt inclusions and embayments from pyroclasts emplaced during explosive eruptions of variable magnitude. Magma saturation pressures were assessed from the dissolved amounts of H2O and CO2 taking into account the melt composition evolution. Both pressures and melt inclusion compositions indicate that (1) Ca-basaltic melts entrapped in high-Mg olivines (Fo89–90) generate Stromboli basalts through crystal fractionation, and (2) the Stromboli plumbing system can be imaged as a succession of magma ponding zones connected by dikes. The 7–10 km interval, where magmas are stored and differentiate, is periodically recharged by new magma batches, possibly ranging from Ca-basalts to basalts, with a CO2-rich gas phase. These deep recharges promote the formation of bubbly basalt blobs, which are able to intrude the shallow plumbing system (2–4 km), where CO2 gas fluxing enhances H2O loss, crystallization and generation of crystal-rich, dense, degassed magma. Chlorine partitioning into the H2O–CO2-bearing gas phase accounts for its efficient degassing (≥69%) under the open-system conditions of strombolian activity. Paroxysms, however, are generated through predominantly closed-system ascent of basaltic magma batches from the deep storage zone. In this situation crystallization is negligible and sulfur exsolution starts at ≤170 MPa. Chlorine remains dissolved in the melt until lower pressures, only 16% being lost upon eruption. Finally, we propose a continuum in explosive eruption energy, from strombolian activity to large paroxysmal events, ultimately controlled by variable pressurization of the deep feeding system associated with magma and gas recharges.
    Description: Published
    Description: 603-626
    Description: 2.3. TTC - Laboratori di chimica e fisica delle rocce
    Description: 3.5. Geologia e storia dei vulcani ed evoluzione dei magmi
    Description: JCR Journal
    Description: reserved
    Keywords: Stromboli ; melt inclusions ; magmatic volatiles ; CO2 fluxing ; magma degassing ; 04. Solid Earth::04.04. Geology::04.04.05. Mineralogy and petrology ; 04. Solid Earth::04.08. Volcanology::04.08.03. Magmas
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  • 39
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    A microscopic information system (MIS) for petrographic analysis (2011)
    Elsevier
    Details
    Publication Date: 2017-04-04
    Description: The database and visualization facilities of Geographic Information System (GIS) software are employed to support the analysis of rock texture from thin section by image processing. A Microscopic Information System (MIS) is hence obtained. The method is applied to transmitted light images of 137 samples obtained from 8 granitoid rocks. A slide scanner and a mount for crossed polarization are used to acquire the input images. For each thin section 5 collimated RGB images are scanned: 4 under different directions of crossed polarization and 1 without polarization. A grain segmentation procedure, based on two region growing functions is applied. The output is converted to vector format and refined using editing tools in the MIS environment, which enables a straightforward match between the input imagery and the final vectorized texture. GIS software provides optimal management of the MIS database, allowing the cumulative measurement of more than 87,000 grains.
    Description: Published
    Description: 665-674
    Description: 2.3. TTC - Laboratori di chimica e fisica delle rocce
    Description: 3.5. Geologia e storia dei vulcani ed evoluzione dei magmi
    Description: 5.3. TTC - Banche dati vulcanologiche
    Description: JCR Journal
    Description: reserved
    Keywords: Granitoid rocks ; Geographic Information System (GIS) ; Image processing ; Petrography ; 04. Solid Earth::04.04. Geology::04.04.05. Mineralogy and petrology ; 04. Solid Earth::04.04. Geology::04.04.09. Structural geology ; 04. Solid Earth::04.04. Geology::04.04.11. Instruments and techniques
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  • 40
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    Laboratory measurements of the physical properties of Triassic Evaporites from Central Italy and correlation with geophysical data (2011)
    Elsevier
    Details
    Publication Date: 2022-04-29
    Description: The Triassic Evaporites (TE) of the Umbria–Marche Apennines, a sedimentary succession made up of a sequence of alternating sulphates (anhydrites and gypsum) and dolostones, represent a key lithology in terms of sealing properties and earthquake triggering. Here we: (1) report laboratory measurements of density, porosity, Vp, Vs, seismic anisotropy and permeability at effective confining pressures from 0 to 100 MPa, conducted on samples of TE collected from both outcrops and boreholes; and (2) attempt to upscale the laboratory results to larger scale geophysical investigation, such as Vp sonic logs, seismic tomography and in situ measurements of pore-fluid pressure. The average laboratory P-wave velocity is 6.0 km/s for dolostones, 4.6 km/s for gypsum–dolostones and 5.8 km/s for anhydrites, at ambient pressure. As effective confining pressure is increased up to 100 MPa, the average P-wave velocity increases to 7.0 km/s for dolostones, 5.3 km/s for gypsum and 6.4 km/s for anhydrites. Vp/Vs ratios appear to be independent of confining pressure, with average values of ∼1.8 to ∼2.2 for sulphates and ∼1.9 to ∼2.2 for dolostones, respectively, for dry and saturated conditions. All samples are characterized by very lowpermeability (10−18m2 to 10−21m2), with the higher values for gypsum–dolostones and fractured dolostones samples. The Vp profiles obtained fromultrasonic laboratory measurementsmatch well the in situ Vp profilesmeasured using sonic logs. In the laboratory, the Vp/Vs ratio increases when pressurized pore fluids are present, in agreement with 4D seismic tomography that relates the increase in Vp/Vs ratio to the migration of fluids during the 1997 Umbria–Marche seismic sequence (Mmax∼6.0) that nucleates within the TE. Our low-permeability values are consistent with deep borehole measurements of high pore-fluid pressure trapped within the Triassic Evaporites.
    Description: Published
    Description: 121-132
    Description: 2.3. TTC - Laboratori di chimica e fisica delle rocce
    Description: JCR Journal
    Description: reserved
    Keywords: Physical Properties, Laboratory measurements, Triassic Evaporites, Geophysical data ; 04. Solid Earth::04.04. Geology::04.04.06. Rheology, friction, and structure of fault zones ; 04. Solid Earth::04.07. Tectonophysics::04.07.07. Tectonics ; 05. General::05.02. Data dissemination::05.02.02. Seismological data
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  • 41
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    Mud volcanoes as potential indicators of regional stress and pressurized layer depth (2011)
    Elsevier
    Details
    Publication Date: 2017-04-04
    Description: Although the use of magmatic volcanoes as indicators of tectonic stress is established, the application of the same principles to mud volcanoes has been overlooked. Here we analyse the onshore Azerbaijan mud volcano province, in the foreland of the Greater Caucasus, and we present the first use of the statistical regional-scale distribution of active mud volcanoes to obtain information about (1) contemporary regional tectonic stress, and (2) the average depth of pressurized source layers. Self-similar clustering suggests that mud is mobilized from a ca. 5 km deep mud-prone layer, and mud volcano strain indicators allow the estimation of a robust present-day direction of regional maximum horizontal stress SH striking ca. 30°E. These results are in excellent agreement with geophysical information about upper crustal structure in the region, and stress data and deformation vectors. We conclude that, besides other fold-and-thrust belts, mud volcano features could be used as a proxy for active stress orientation and source layer determination in inaccessible settings, such as underwater or even the surface of planets where mud volcanoes are considered to be indicators of mobilized fluids.
    Description: Published
    Description: 32-47
    Description: 1.10. TTC - Telerilevamento
    Description: 3.2. Tettonica attiva
    Description: 3.3. Geodinamica e struttura dell'interno della Terra
    Description: JCR Journal
    Description: reserved
    Keywords: Mud volcanoes ; Stress indicators ; Self-similar clustering ; Azerbaijan Greater Caucasus ; Mediterranean Ridge ; 04. Solid Earth::04.04. Geology::04.04.99. General or miscellaneous ; 04. Solid Earth::04.07. Tectonophysics::04.07.05. Stress ; 04. Solid Earth::04.07. Tectonophysics::04.07.07. Tectonics
    Repository Name: Istituto Nazionale di Geofisica e Vulcanologia (INGV)
    Type: article
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  • 42
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    Late Quaternary tectonics of the Vallo di Diano basin (southern Apennines, Italy) (2011)
    Elsevier
    Details
    Publication Date: 2017-04-04
    Description: We discuss new data concerning the late Quaternary tectonics of the Vallo di Diano basin, the largest intramontane depression in the southern Apennines chain (Italy). The southern Apennines axis is currently subject to NEeSW extension. Here, active NW-trending normal faults are associated with strong earthquakes (M 〉 6), with average recurrence times 〉1 ka. The Vallo di Diano basin is a half-graben bounded by an extensional fault system VDFS (Vallo di Diano Fault System), featuring three major NW-trending, SW-dipping, w15e17 km long fault segments. Holocene faulting and possible historical seismicity have been documented only for the northern fault segment. No major historical earthquakes can be associated with the other fault segments, and the recent sedimentary and structural evolution of the basin is still poorly constrained. As a consequence, its seismogenetic potential has probably been underestimated. We found evidence of late PleistoceneeHolocene faulting in the relay zone of the central and southern fault segments bordering the basin. Here, late Pleistocene volcaniclastic layers at the apex of an alluvial fan are affected by normal displacements on the order of w1 m. Additionally, in the same area we recognized a previously unreported, 9 km long and 0.5e1.4 km wide set of scarplets (ranging in height between w1 m and 2.5 m) affecting late Pleistoceneelate Holocene alluvial fans. The last deformation is younger than 3 ka BP. Due to the geometric arrangement of these scarplets and the long-term displacement along the Vallo di Diano Fault System, we hypothesize that the central and southern fault segments belong to a w32 km long hard-linked system, capable of generating Mw 〉 6.5 earthquakes. The Vallo di Diano basin is thus bounded to the east for its entire length (w45 km) by an active segmented extensional fault system. Therefore it has to be considered one of the major seismogenic sources in southern Italy.
    Description: Italian Ministry of University and Research (Project FIRB “Research and Development of New Technologies for Protection and Defence of Territory from Natural Risks”, W.P. C3 “Crustal Imaging in Italy”)
    Description: Published
    Description: 3167-3183
    Description: 3.2. Tettonica attiva
    Description: JCR Journal
    Description: reserved
    Keywords: fault scarp ; relay ramp ; alluvial fan ; Southern Apennines ; 04. Solid Earth::04.07. Tectonophysics::04.07.07. Tectonics
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  • 43
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    Short residence times for alkaline Vesuvius magmas in a multi-depth supply system: Evidence from geochemical and textural studies (2011)
    Elsevier
    Details
    Publication Date: 2017-04-04
    Description: It is crucial to understand magma chamber chemico-physical conditions and residence times for high-risk volcanoes because these factors control the occurrence and size of future eruptions. In order to define magmatic pressure–temperature conditions and residence times at the Somma–Vesuvius volcano, we studied the geochemistry and texture of selected past eruptions that are representative of the entire volcanic history. Our petrological model indicates a multi-depth magma chamber composed of a deeper tephritic (350– 400 Mpa) magma layer, which fed Strombolian and effusive eruptions during open-conduit activity, and an upper (200–250 Mpa) phonolitic level, which supplied the high explosive events that followed closedconduit repose time. This upper reservoir matches the inferred transition between sedimentary sequences and metamorphic basement. At this level, the presence of a structural and lithological discontinuity favors magma storage during closed-conduit periods. The prevalent differentiation process was fractional crystallization during the magma cooling associated with upward migration of less dense, evolved liquids. Our results indicate that major steam exolution occurred during the late crystallization stage of phonolites, which accounts for the high Volcanic Explosivity Index (VEI) of eruptions supplied by these melts. Moreover, our phenocryst CSD data reveal the rapid crystallization and differentiation (decades to centuries) of alkaline Somma–Vesuvius magmas. This implies that the 400 km2 partial melting zone detected by tomography studies at 8–10 km depth beneath Vesuvius should consist of differentiated magma that is already capable of generating a large-scale (plinian) explosive event if renewed activity develops out of the present closed-conduit state. Additionally, because our microlite CSD data indicate rapid magma migration from the chamber toward the surface, precursory activity could appear only short time before a major eruption.
    Description: Published
    Description: 133–143
    Description: 2.3. TTC - Laboratori di chimica e fisica delle rocce
    Description: 3.5. Geologia e storia dei vulcani ed evoluzione dei magmi
    Description: 3.6. Fisica del vulcanismo
    Description: JCR Journal
    Description: reserved
    Keywords: residence time ; phonolite ; Vesuvius ; 04. Solid Earth::04.01. Earth Interior::04.01.04. Mineral physics and properties of rocks ; 04. Solid Earth::04.04. Geology::04.04.05. Mineralogy and petrology ; 04. Solid Earth::04.04. Geology::04.04.07. Rock geochemistry ; 04. Solid Earth::04.04. Geology::04.04.10. Stratigraphy
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  • 44
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    The feeding system of Agnano–Monte Spina eruption (Campi Flegrei, Italy): Dragging the past into present activity and future scenarios (2011)
    Elsevier
    Details
    Publication Date: 2017-04-04
    Description: Magmatic processes triggering eruptions at Campi Flegrei caldera (southern Italy) and their relationships with the widespread emissions of fluids and caldera unrest episodes, are poorly constrained. The 4.1 ka B.P. Agnano–Monte Spina eruption, the reference event for a future large-size explosive eruption at Campi Flegrei, was investigated to shed light, through melt inclusion and isotope analyses, on the geochemical processes operating in the plumbing system. Chemical and isotopic data on whole rocks and glasses suggest that at least two magma batches mixed during the course of the eruption. Melt inclusion data highlight the pre-eruption storage conditions of two magmatic end-members. One end-member is like the less differentiated (shoshonitic) Campi Flegrei erupted magma, while the other could be a residual of the Neapolitan Yellow Tuff magma. Mixing between these two components was driven by a large gas phase which sustained the ascent of magmas of deep provenance. The H2O and CO2 contents in pyroxene-hosted melt inclusions yield entrapment pressures between 107 and 211 MPa, corresponding to depths between 4 and 8 km. The degassing trends reveal two extreme patterns. One pattern, already documented in the literature, is the volatile signature of poorly differentiated magmas ascending from more than 8 km depth, while the other is related to a gas-dominated magma, flushed by a CO2-rich gas phase partly released from the deep reservoir. This study provides a conceptual frame for unrest phases at Campi Flegrei, such as the 1982–84 event. Uplift phases can be related to closed-system ascent of magmas and fluids from more than 8 km depth, and their emplacement at shallow levels. This leads the shallow system to store, and then progressively release, the accumulated gas. In this view, both unrest episodes and eruptions could be strongly influenced by both the achievement of a critical upper limit of gas storage in the shallow magmatic reservoir and the stress and fracturing state of the roof rocks. The present results help to constrain the preeruptive conditions expected at Campi Flegrei caldera in case of a future large-size eruptive event.
    Description: Published
    Description: 135–147
    Description: 2.3. TTC - Laboratori di chimica e fisica delle rocce
    Description: 3.5. Geologia e storia dei vulcani ed evoluzione dei magmi
    Description: JCR Journal
    Description: reserved
    Keywords: Sr and Nd isotopes ; Melt inclusions ; Gas flushing ; Magma mixing ; 04. Solid Earth::04.04. Geology::04.04.05. Mineralogy and petrology ; 04. Solid Earth::04.08. Volcanology::04.08.03. Magmas ; 04. Solid Earth::04.08. Volcanology::04.08.05. Volcanic rocks
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  • 45
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    Understanding stress and deformation in active volcanoes (2010)
    Elsevier
    Details
    Publication Date: 2021-06-15
    Description: No eruption, no caldera collapse, and no landslide can take place in a volcano unless its state of stress is suitable for the associated type of rock failure. The state of stress, in turn, results in deformation, and both stress and deformation depend on the mechanical properties of the rocks that constitute the volcano. Understanding stress and deformation in volcanoes is thus of fundamental importance for understanding unrest periods and for accurate forecasting volcano failure, such as may result in large-scale lateral and vertical collapses and eruptions.
    Description: Published
    Description: 1-3
    Description: 2.3. TTC - Laboratori di chimica e fisica delle rocce
    Description: JCR Journal
    Description: reserved
    Keywords: stress, deformation, volcano tectonics, physical propertie of volcanic rocks ; 04. Solid Earth::04.07. Tectonophysics::04.07.05. Stress ; 04. Solid Earth::04.07. Tectonophysics::04.07.07. Tectonics ; 04. Solid Earth::04.08. Volcanology::04.08.05. Volcanic rocks ; 04. Solid Earth::04.08. Volcanology::04.08.06. Volcano monitoring ; 04. Solid Earth::04.08. Volcanology::04.08.08. Volcanic risk ; 05. General::05.02. Data dissemination::05.02.03. Volcanic eruptions
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  • 46
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    Analysis of small magnitude seismic sequences along the Northern Apennines (Italy) (2010)
    Elsevier
    Details
    Publication Date: 2017-04-04
    Description: We analyze the seismicity of a small sector of the Northern Apennines merging data from the Italian seismic bulletin with original data collected by temporary seismic networks. Our attention is focused on the region enclosed between the Apenninic watershed and the Adriatic Sea. This portion of belt is interested by the occurrence of diffuse crustal seismicity and small-to-moderate earthquakes. In this paper we study the five small sequences with mainshock having Mw 〈 4.7 that in the past 15 years hit the area. Our interest is addressed to better understand the relationship between these events and the regional seismotectonic setting in terms of seismicity distribution and stress field. Two regions with different behavior in the seismic release can be distinguished: (i) along the watershed where seismicity is clustered at shallow depths (〈 15 km) and where strong earthquakes occurred in the past, (ii) an eastern portion where the seismicity is distributed across all of the crustal volume, locally reaching depths down to 30 km. The focal mechanism of the seismic sequences shows mainly normal fault kinematics coherent with the regional stress field. Detailed stress field analysis suggests a rotation of the principal stress axis moving from the axial part of the chain toward the Adriatic Sea to the east.
    Description: Published
    Description: 136-144
    Description: 1.1. TTC - Monitoraggio sismico del territorio nazionale
    Description: 3.2. Tettonica attiva
    Description: JCR Journal
    Description: reserved
    Keywords: Northern Apennines ; Stress field ; Focal mechanisms ; Seismicity ; 04. Solid Earth::04.06. Seismology::04.06.01. Earthquake faults: properties and evolution ; 04. Solid Earth::04.07. Tectonophysics::04.07.07. Tectonics
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  • 47
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    The upper lithostratigraphic unit of ANDRILL AND-2A core (Southern McMurdo Sound, Antarctica): Local Pleistocene volcanic sources, paleoenvironmental implications and subsidence in the southern Victoria Land Basin (2010)
    Elsevier
    Details
    Publication Date: 2017-04-04
    Description: We report results from the study of the uppermost 37 m of the Southern McMurdo Sound (SMS) AND-2A drill core, corresponding to the lithostratigraphic unit 1 (LSU 1), the most volcanogenic unit within the core. We present data on the age, composition, volcanological and depositional features of the volcanic sedimentary and tephra deposits of LSU 1 and discuss their source, mechanisms of emplacement and environment of deposition. Sedimentary features and compositional data indicate shallow water sedimentation for the whole of LSU 1. Most of LSU 1 deposits are a mixture of near primary volcanic material with minor exotic clasts derived from the Paleozoic crystalline basement rocks. Among volcanic materials, glassy particles are the most abundant. They were produced by mildly explosive basaltic eruptions occurring in subaerial and subaqueous environments. The Dailey Islands group, 13 km south-southwest of the SMS drill-site, has been identified as a possible source for the volcanics on the basis of similarity in composition and age. 40Ar–39Ar laser step-heating analyses on a lava sample from Juergens Island yields an age of 775 ± 22 ka. Yet because of the minimal reworking features of vitriclasts, preservation of fragile structures in volcaniclastic sediments and evidence for volcanic seamounts to the north of the Dailey Islands, it is likely that some of the material originated also from vents close to the drill-site. Evidence for local volcanic sources and for deposition of sediments in a shallow marine environment provides indications about the local paleogeography and implications for the subsidence history of the southern Victoria Land Basin from Pleistocene to Recent.
    Description: Published
    Description: 142-161
    Description: 3.5. Geologia e storia dei vulcani ed evoluzione dei magmi
    Description: 3.8. Geofisica per l'ambiente
    Description: JCR Journal
    Description: reserved
    Keywords: Antarctica ; volcaniclastic sediments ; Erebus Volcanic Province ; paleoenvironment reconstruction ; Victoria Land Basin ; 04. Solid Earth::04.04. Geology::04.04.05. Mineralogy and petrology ; 04. Solid Earth::04.04. Geology::04.04.08. Sediments: dating, processes, transport
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  • 48
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    A Microscopic Information System (MIS) for petrographic analysis (2010)
    Elsevier
    Details
    Publication Date: 2017-04-04
    Description: The database and visualization facilities of Geographic Information System (GIS) software are employed to support the analysis of rock texture from thin section by image processing. A Microscopic Information System (MIS) is hence obtained. The method is applied to transmitted light images of 137 samples obtained from 8 granitoid rocks. A slide scanner and a mount for crossed polarization are used to acquire the input images. For each thin section 5 collimated RGB images are scanned: 4 under different directions of crossed polarization and 1 without polarization. A grain segmentation procedure, based on two region growing functions is applied. The output is converted to vector format and refined using editing tools in the MIS environment, which enables a straightforward match between the input imagery and the final vectorized texture. GIS software provides optimal management of the MIS database, allowing the cumulative measurement of more than 87 000 grains.
    Description: In press
    Description: 2.3. TTC - Laboratori di chimica e fisica delle rocce
    Description: 3.5. Geologia e storia dei vulcani ed evoluzione dei magmi
    Description: 5.3. TTC - Banche dati vulcanologiche
    Description: JCR Journal
    Description: open
    Keywords: Granitoid rocks ; Geographic Information System ; Image processing ; Petrography ; 04. Solid Earth::04.04. Geology::04.04.05. Mineralogy and petrology ; 04. Solid Earth::04.04. Geology::04.04.09. Structural geology ; 04. Solid Earth::04.04. Geology::04.04.11. Instruments and techniques
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  • 49
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    The pre-eruptive volatile contents of recent basaltic and pantelleritic magmas at Pantelleria (Italy) (2010)
    Elsevier
    Details
    Publication Date: 2017-04-04
    Description: Pantelleria Island, located in the Sicily Channel Rift Zone (Italy), is the type locality for the peralkaline rhyolitic rocks called pantellerites. In the last 50 ka, after the large Green Tuff caldera-forming eruption, volcanic activity at Pantelleria has consisted of effusive and explosive eruptions mostly vented inside and along the rim of the caldera and producing silicic lava flows, lava domes and poorly dispersed pantelleritic pumice fall deposits. Basaltic cinder cones and lava flows are only present outside the caldera in the NW sector of the island. The most recent basaltic (Cuddie Rosse, 20 ka) and pantelleritic (Cuddia Randazzo and Cuddia del Gallo, 6 ka) pyroclastic products were sampled to investigate magmatic volatile contents through the study of melt inclusions. The melt inclusions in pyroxene and olivine phenocrysts of Cuddie Rosse scoriae have an alkali basalt composition. The dissolved volatiles comprise 0.9–1.6 wt.% H2O, several hundred ppm of CO2, 1600–2000 ppm of sulphur and 500–900 ppm of chlorine. The water–carbon dioxide couple gives a confining pressure 2 kbar prior to the eruption. This result indicates that episodes of magma ponding and crystallization occurred in the upper crust prior to eruption. The melt inclusions in feldspar, fayalite and aenigmatite phenocrysts of Cuddia del Gallo and Cuddia Randazzo pumice have a pantelleritic composition (Agpaitic Indices 1.3–2.1), up to 4.4 wt.% H2O, 8700 ppm Cl, 6000 ppm F, and CO2 below the detection limit. Sulphur averaging 420 ppm has been measured in Cuddia Randazzo melt inclusions. These data indicate relatively high volatile contents for these low-energy Strombolian-type eruptions. Melt inclusions in Cuddia del Gallo pumice show the most evolved composition (Agpaitic Indices 2–2.1) and the highest volatile content, in agreement with fluid saturation conditions in the magma chamber prior to the eruption. This implies a confining pressure of 1 kbar for the top of the pantelleritic reservoir. The composition of melt inclusions and mineralogical assemblage of Cuddia Randazzo pumice indicate that it has a lower evolutionary degree (Agpaitic Indices 1.3–1.8) and lower pre-eruptive Cl and H2O contents than Cuddia del Gallo pumice. An increase in pressure due to the exsolution of volatiles in the upper part of the pantelleritic reservoir may have triggered the Cuddia del Gallo explosive eruption. Evidence of widespread pre-eruptive mingling between trachytes and pantellerites suggests that the intrusion of trachytic magma into the pantelleritic reservoir likely played a major role in destabilizing the magma system just prior to the Cuddia Randazzo event.
    Description: In press
    Description: 2.3. TTC - Laboratori di chimica e fisica delle rocce
    Description: 3.5. Geologia e storia dei vulcani ed evoluzione dei magmi
    Description: JCR Journal
    Description: reserved
    Keywords: Pantelleria ; peralkaline ; volatiles ; melt inclusions ; eruptive style ; 04. Solid Earth::04.04. Geology::04.04.05. Mineralogy and petrology ; 04. Solid Earth::04.08. Volcanology::04.08.03. Magmas
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  • 50
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    Quantitative analysis of extensional joints in the southern Adriatic foreland (Italy), and the active tectonics of the Apulia region (2010)
    Elsevier
    Details
    Publication Date: 2017-04-04
    Description: The Adriatic foreland of the Apennines comes ashore only in Apulia (easternmost Italy). Its southern part, our study area, lacks any structural analysis devoted to define its recent-to-active tectonics. Throughout the Quaternary, this region was affected by mild brittle deformation with rare faults, characterized by small displacement, and widespread extension joints, frequently organized in sets. Therefore, we conducted a quantitative and systematic analysis of the joint sets affecting Quaternary deposits, by applying an inversion technique ad hoc to infer the orientation and ratio of the principal stress axes, R = (σ2 - σ3)/(σ1 - σ3). Within a general extensional regime, we recognized three deformational events of regional significance. The oldest event, constrained to the early and middle part of the Middle Pleistocene, is characterized by variable direction of extension and R between 0.64-0.99. The penultimate event, dated late Middle Pleistocene, is characterized by an almost uniaxial tension, with a horizontal σ3 striking ~N43°E; R is high, between 0.85-0.99. The most recent event is characterized by the lowermost R values, that never exceed 0.47 and are frequently 〈0.30, indicating a sort of horizontal „radial‟ extension. This event is not older than the Late Pleistocene and possibly reflects the active stress field still dominating the entire study area.
    Description: In press
    Description: 3.2. Tettonica attiva
    Description: JCR Journal
    Description: open
    Keywords: Quaternary tectonics ; brittle deformation ; fracture ; Pleistocene ; 04. Solid Earth::04.04. Geology::04.04.09. Structural geology ; 04. Solid Earth::04.07. Tectonophysics::04.07.05. Stress ; 04. Solid Earth::04.07. Tectonophysics::04.07.07. Tectonics
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