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  • Books  (95)
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  • Cham :Springer International Publishing :  (95)
  • Bremerhaven : Alfred-Wegener-Inst. für Polar- und Meeresforschung
  • University of Virginia Library
  • Wabern : Federal Office of Topography, Swiss Geological Survey
  • 577  (49)
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  • Books  (95)
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  • 1
    Keywords: Immunology. ; Medicine History. ; Medicine Research. ; Biology Research. ; Immunology. ; History of Medicine. ; Biomedical Research.
    Description / Table of Contents: A -- B -- C -- D -- E -- F -- G -- H -- I -- J -- K -- L -- M -- N -- O -- P -- Q -- R -- S -- T -- U -- V -- W -- Z.
    Abstract: Hundreds of eponyms are used within the field of immunology—Petri dish, Crohn’s disease, Bence Jones protein, Kupffer cells, Freund's adjuvant, Ouchterlony immunodiffusion, to name just a few—but most of us don't know much about the individuals who gave their names to these terms. Where were they born and educated, what other accomplishments are they credited with, why has history chosen to remember them, or not? This book presents the first comprehensive collection of immunologic eponyms, and through them tells the story of this fascinating field, from its earliest beginnings to present day. Organized by surname and meticulously cross-referenced and indexed, this book offers historical anecdotes and little-known facts which scientists, clinicians, students, and general readers will find captivating and memorable. A one-of-a-kind introduction to immunology that serves as both a history lesson and current reference on the diseases, treatments, and individuals who have been crucial to this field.
    Type of Medium: Online Resource
    Pages: XXVIII, 405 p. , online resource.
    Edition: 1st ed. 2023.
    ISBN: 9783031145292
    DDC: 571.96
    Language: English
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  • 2
    Keywords: Biotic communities. ; Soil science. ; Plant ecology. ; Geomorphology. ; Ecophysiology. ; Conservation biology. ; Ecology . ; Ecosystems. ; Soil Science. ; Plant Ecology. ; Geomorphology. ; Ecophysiology. ; Conservation Biology.
    Description / Table of Contents: 1 Introduction -- Part I: Forest and woodland biomes -- 2 White sand ecosystems in the Amazon basin: geographic distribution, distinctive features, and ecology. An overview -- 3 The forests of the Rio Negro basin in the north-western Amazon: a phytosociological classification -- 4 Amazon caatinga complex: sclerophyllous vegetation on nutrient-poor white sand soils -- Part II: Meadow biomes -- 5 Mapping white-sand ecosystems by integrating Global PALSAR-2 and SENTINEL-1 with NDVI (LANDSAT data) -- 6 The study areas: landscapes and soils -- 7 Soil properties, formation, distribution, and classification -- 8 Origin and sources of sand: from highlands to lowlands -- 9 Sand dynamics and distribution: a geo-sedimentological approach -- 10 Features and trends of meadow landscape evolution -- 11 Meadow phytodiversity: flora, endemism, vegetation types, and geographic distribution patterns -- 12 Synthesis: white-sand and meadow-vegetation relationships.
    Abstract: The book represents a multidisciplinary approach to understanding soil–landscape–vegetation relationships and, specifically, the ecophysiology of plant communities developing on sandy soils of very low fertility that are subject to seasonal flooding. It provides an overview of the white sand ecosystems within the Amazon basin, and focuses on the forest and herbaceous (meadows) vegetation growing on the dystrophic sandy soils of the upper Negro and Orinoco river basins. Several chapters describe physiographic aspects of the study area using integrated remote sensing and in situ sampling. By doing so they attain a comprehensive description of the origin and evolution of soils and landscapes, an advanced classification of soils, and a mapping of the geographic distribution of psammophilous vegetation. This volume also provides a phytosociological classification of extensive forested areas, and a detailed description of the structure and diversity of little-known herbaceous formations. It targets professionals in the fields of ecology, ecophysiology, geomorphology, soils, vegetation, and the environmental sciences. The information it offers may be of significant use to researchers, protected area planners, and environmental policy makers.
    Type of Medium: Online Resource
    Pages: XIV, 541 p. 136 illus., 122 illus. in color. , online resource.
    Edition: 1st ed. 2023.
    ISBN: 9783031207990
    Series Statement: Ecological Studies, Analysis and Synthesis, 247
    DDC: 577
    Language: English
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  • 3
    Keywords: Ecology . ; Vertebrates. ; Animal behavior. ; Population biology. ; Ecology. ; Vertebrate Zoology. ; Behavioral Ecology. ; Population Dynamics.
    Description / Table of Contents: 1. What do we know about mammal movement in African tropical forests? -- 2. Movements patterns and population dynamics of giant forest hog groups in Kibale National Park, Uganda -- 3. Forest elephant movements in Central Africa – megafauna need megaspaces -- 4. Elephant movements, abundance and use of water sources in Kibale National Park, Uganda -- 5. Movement ecology and evolutionary history of forest buffalo -- 6. Site fidelity and home range shifts in a leaf-eating primate -- 7. Primate movements across the nutritional landscapes of Africa -- 8. Conditions facilitating a “landscape of fear from disease” in African forest mammals -- 9. Do seasonally frugivory and cognition shape foraging movements in wild western gorillas? -- 10. Females Move in Tight Crowds, Males Roam: Society and Movement Ecology of Mandrills -- 11. Linking Movement Ecology to Conservation Biology.
    Abstract: This book brings a unique perspective to animal movement studies because all studies come from African tropical environments where the great diversity, either biological and structurally (trees, shrubs, vines, epiphytes), present the animals with several options to fulfil their basic needs. These conditions have forced the evolution of unique movement patterns and ecological strategies. The book follows on our previous book “Movement Ecology of Neotropical Forest Mammals” but focuses on tropical African forests. Movement is an essential process in the life of all organisms. Animals move because they are looking for primary needs such as food, water, cover, mating and to avoid predators. Understanding the causes and consequences of animal movement is not an easy task for behavioural ecologists. Many animals are shy, move in secretive ways and are very sensible to human presence, therefore, studying the movements of mammals in tropical environments presents logistical and methodological challenges. However, researchers have recently started to be solved these challenges and exciting new information is emerging. In this book we are compiling a set of extraordinary studies where researchers have used new technology and the strongest methodological approaches to understand movement patterns in wild African forest mammals. This second book should inspire early career researchers to investigate wild mammal´s movements in some of the most amazing forest in the world: African tropical forests. .
    Type of Medium: Online Resource
    Pages: XVII, 196 p. 42 illus., 36 illus. in color. , online resource.
    Edition: 1st ed. 2023.
    ISBN: 9783031270307
    DDC: 577
    Language: English
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  • 4
    Online Resource
    Online Resource
    Cham :Springer International Publishing :
    Keywords: Ecology . ; Biodiversity. ; Conservation biology. ; Environmental management. ; Environmental geography. ; Ecology. ; Terrestial Ecology. ; Biodiversity. ; Conservation Biology. ; Environmental Management. ; Integrated Geography.
    Description / Table of Contents: Introduction -- Biomes: Concepts, Characteristics and Terminology -- Profiles of Angola’s Biomes and Ecoregiens -- Landscapes: Geology, Hydrology and Geomorphology.
    Abstract: This open access book richly illustrates the first, and comprehensive, account of the country’s biomes and ecoregions, the driving forces that account for their diversity and vulnerability, and the ecological principles that provide an understanding of the patterns and processes that have shaped landscapes, ecoregions, and ecosystems. Angola encompasses the greatest diversity of terrestrial biomes and is the second richest in terms of ecoregions, of any African country. Yet its biodiversity and the structure and functioning of its ecosystems are largely undocumented. The author draws on personal field observations from over 50 years of involvement in ecological and conservation studies in Angola and across Southern Africa. The vast recent literature published by researchers in neighboring, better resourced countries provides depth to the accounts of ecological principles and processes relevant to Angola and thus contributing to the understanding and sustainable management of its natural resources. .
    Type of Medium: Online Resource
    Pages: XIX, 459 p. 220 illus., 170 illus. in color. , online resource.
    Edition: 1st ed. 2023.
    ISBN: 9783031189234
    DDC: 577
    Language: English
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  • 5
    Online Resource
    Online Resource
    Cham :Springer International Publishing :
    Keywords: Ecology . ; Animal culture. ; Sustainability. ; Geographic information systems. ; Environment. ; Ecology. ; Animal Science. ; Sustainability. ; Geographical Information System. ; Environmental Sciences.
    Description / Table of Contents: Part 1: Introduction to squirrels of the world and their conservation trends. Chapter 1: The World’s Squirrel Taxonomy -- Chapter 2: Evolution, habitat trends, and extinction rate estimates of the world squirrels -- Part 2: Squirrels of the world in the Anthropocene. Chapter 3: Habitat Trends and the Squirrel-Human Interface -- Chapter 4: A Meta-analysis based on Open Access Big Data Mining of Global Predicted Squirrel Distribution Models with Machine Learning for IUCN Conservation Status and Trend Policy Assessments -- Chapter 5: Squirrels in Cities -- Chapter : Squirrels in the Tropics -- Chapter 7: Squirrels on Islands -- Chapter 8: Tree squirrels in old-growth forests? -- Chapter 9: Can squirrels be used as indicators to identify and protect old-growth forest reserves? -- Chapter 10: Squirrel Economics -- Part 3: Problems and governance in the squirrel world. Chapter 11: Squirrel Hunting Regulations and Enforcement (Or Lack Thereof) -- Chapter 12: Where do the World’s Squirrel Hotspots and Coldspots of 230+ species go with Climate change 2100? -- Chapter 13: Squirrel’s marginalization and modern lack of conservation and poor sustainability outlook as a call to good action -- Part 4: First conclusions and the way forward. Chapter 14: A Conservation Management SWOT analysis for over 300 Squirrels of the World using 132 GIS layers confirming the PESTLE assessment -- Chapter 15: First Conclusions, Success stories, and Calls-to-action for the conservation of the world’s squirrels.
    Abstract: This book attempts to move the family of squirrels (Sciuridae) out of the shadow of large charismatic mammals and to highlight management failures with the goal of moving towards an improved conservation approach. Particular attention is paid to the influence of taxonomic science on squirrel conservation. In addition, the authors show how human-driven climate change, global change and modern politics are shaping global squirrel populations as well as their surrounding environments and ecosystems. Squirrels are widespread around the globe, naturally occurring on every continent except Antarctica and Oceania, and they are certainly among the animals most commonly encountered in everyday life. Despite this, the authors of this volume identify worrying gaps in squirrel conservation. Squirrels are often hunted, trapped, poached, and stressed, and management strategies and legislation are often devised in the absence of proper knowledge of issues such as population sizes, taxonomies, and trends. Together, this can result in severe population declines and even species extinction. By assessing their taxonomic situation, ecology, the evolution and divergence of Sciuridae around the globe, and squirrels’ well-being across habitats, the authors set a baseline from which to launch future investigations into the conservation of squirrels and other species. Additionally, the authors highlight the influences of climate change, unsustainable growth, and various man-made threats to the future of this family.
    Type of Medium: Online Resource
    Pages: XVII, 380 p. 228 illus., 221 illus. in color. , online resource.
    Edition: 1st ed. 2023.
    ISBN: 9783031235474
    DDC: 577
    Language: English
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  • 6
    Keywords: Ecology . ; Conservation biology. ; Zoology. ; Animal culture. ; Biotic communities. ; Freshwater ecology. ; Marine ecology. ; Ecology. ; Conservation Biology. ; Zoology. ; Animal Science. ; Ecosystems. ; Freshwater and Marine Ecology.
    Description / Table of Contents: 1. Introduction to Rangeland Wildlife Ecology and Conservation -- Part I Rangeland Ecosystems and Processes -- 2. Rangelands of Western North America -- 3. A History of North American Rangelands -- 4. Western Rangeland Livestock Production Systems and Grazing Management -- 5. Manipulation of Rangeland Wildlife Habitats -- 6. Role and Management of Fire in Rangelands -- 7. Water is Life: Importance and Management of Riparian Areas for Rangeland Wildlife -- 8. Rangeland Biodiversity -- Part II Species Accounts -- 9. Prairie Grouse -- 10. Sage-Grouse -- 11. Quails -- 12. Rangeland Songbirds -- 13. Wetland Birds of Rangelands -- 14. Avian Predators in Rangelands -- 15. Burrowing Rodents -- 16. Mesocarnivores of Western Rangelands -- 17. Black-tailed and Mule Deer -- 18. White-tailed Deer -- 19. Pronghorn -- 20. Elk -- 21. Feral Equids -- 22. Mountain Ungulates -- 23. American Bison -- 24. Large Carnivores -- 25. Amphibians and Reptiles -- 26. Insects in Grassland Ecosystems -- Part III Social-Ecological Considerations -- 27. Wildlife, Rural Communities, and the Rangeland Livelihoods they Share: Opportunities in a Diverse Economies Approach -- 28. Living with Predators: A 20-year Case Study in the Blackfoot River Watershed of Montana -- 29. A Perspective on Rangeland and Wildlife Disciplines: Similarities Over Differences -- 30. Future of Rangeland Wildlife in North America.
    Abstract: This open access book reviews the importance of ecological functioning within rangelands considering the complex inter-relationships of production agriculture, ecosystem services, biodiversity, and wildlife habitat. More than half of all lands worldwide, and up to 70% of the western USA, are classified as rangelands—uncultivated lands that often support grazing by domestic livestock. The rangelands of North America provide a vast array of goods and services, including significant economic benefit to local communities, while providing critical habitat for hundreds of species of fish and wildlife. This book provides compendium of recent data and synthesis from more than 100 experts in wildlife and rangeland ecology in Western North America. It provides a current and in-depth synthesis of knowledge related to wildlife ecology in rangeland ecosystems, and the tools used to manage them, to serve current and future wildlife biologists and rangeland managers in the working landscapes of the West. The book also identifies information gaps and serves as a jumping-off point for future research of wildlife in rangeland ecosystems. While the content focuses on wildlife ecology and management in rangelands of Western North America, the material has important implications for rangeland ecosystems worldwide.
    Type of Medium: Online Resource
    Pages: XI, 1023 p. 111 illus., 94 illus. in color. , online resource.
    Edition: 1st ed. 2023.
    ISBN: 9783031340376
    DDC: 577
    Language: English
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  • 7
    Keywords: Ecology . ; Sustainability. ; Energy policy. ; Energy and state. ; Schools of economics. ; Ecology. ; Sustainability. ; Energy Policy, Economics and Management. ; Heterodox Economics.
    Description / Table of Contents: Part I - Money and its role in the economy -- 1. Introduction: the world is on a collision course -- 2. What is money? -- 3. Money is like the ‘blood’ of the economy -- Part II Money and the unsustainability in stricto sensu -- 4. The growth imperative inherent in our financial system -- 5. The effect of the money interest rate on money supply, demand and growth -- 6. Economic growth in the long run is unsustainable -- 7. Economic growth or unemployment -- Part III. Money and inequality -- 8. Our current monetary system produces income inequality -- 9. Moral-ethic aspects of interest-induced inequality -- Part IV Natural money as solution -- 10. Gesell’s solution -- 11. Gesell’s Solution to achieve the SDGs -- 12. How to implement Gesell’s solution in today’s world -- 13. Alternatives to Gesell’s solution -- 14. Experiences with Gesell’s solution -- Part V Outlook and final considerations -- 15. Towards a Development at Human Scale -- 16. Economic resilience in presence of externals shocks -- 17. Final considerations.
    Abstract: This book combines the field of economics —especially monetary theory— with other disciplines like ecology, physics, humanities, social sciences and development theory. This transdisciplinary approach makes the book a unique contribution for researchers, students, policy makers and professionals working in governmental or nongovernmental institutions, as well as anyone interested in society’s well-being and achieving a true social-ecological transformation. It is written in an accessible language in order to reach a broad audience. In 2015, more than 190 world leaders recognized that the world is on a “collision course” (Max-Neef) and committed to 17 Sustainable Development Goals (SDGs). Many conferences and high-level meetings have been held since then, and one of the most frequently discussed topics is how to finance these goals. There is a widespread belief that coming up with more money for sustainable development will “do the trick”. Usually, the discussions focus on finding additional financial resources in order to achieve the goals faster. In this book it is argued that not only is more money needed, but it needs to be a different kind of money. The book demonstrates that ALL but one of the SDGs are directly linked to our monetary system, which —being completely unnatural— can be seen as the most important, but at the same time least recognized, reason for market failure. Many people think we just need to do more, faster, better. Very few say that we have done things fundamentally wrong and that the institutions and values which motivated us to do those things need to be changed. It will be concluded that only if we change our unnatural design of money to a more natural one, will we be able to reach these goals.
    Type of Medium: Online Resource
    Pages: XXV, 357 p. 54 illus. , online resource.
    Edition: 1st ed. 2023.
    ISBN: 9783031377686
    DDC: 577
    Language: English
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  • 8
    Online Resource
    Online Resource
    Cham :Springer International Publishing :
    Keywords: Ecology . ; Biotic communities. ; Botany. ; Bioclimatology. ; Ecophysiology. ; Ecology. ; Ecosystems. ; Plant Science. ; Climate Change Ecology. ; Ecophysiology.
    Description / Table of Contents: 1- Basic concepts of ecology applied on the neotropic ecosystems -- 2 - Natural resources and sustainable development in Peru -- 3 - Classification of the Peruvian Ecosystems -- 4 - Peruvian ecosystems geography -- 5 - Biodiversity and endemism of the Andes -- 6 - Ecological communities, populations and metapopulations -- 7 - Succession and change of the ecosystems -- 8 - Biodiversity of the Amazonia Basin -- 9 - Peruvian protected natural areas -- 10 - The paramo ecosystems -- 11 - The Humboldt National Forest -- 12 - The Northwest Biosphere Reserve -- 13 - Urban ecosystems and development -- 14 - Climate changes -- 15 - Traditional land-use systems and agrobiodiversity in Peru -- Index.
    Abstract: This book focuses on ecosystems and species adaptations in the unique Peruvian Andean-Amazonian region. The presence of the Andes as the backbone is the cause of the huge ecosystem diversity and biodiversity of species that characterize the Andean-Amazonian ecosystems. The complex orography of Peru as results of the Andes presence in its tropical setting favors the occurrence of local climatic features that provide diverse environmental conditions for multiple, unique plant and animal species, many of them endemic to the Andes. The book will introduce the reader to the climatic history and geography of the Peruvian Andes and the Peruvian Natural Areas Protection system focusing on the Manu and Northwest biosphere reserves given their relevant ecological importance as well as the relationship between them and the local population. Important global topics like urbanization, deglaciation and global warming will be analyzed and discussed due to their impact in the Andes-Amazon ecosystems. Finally, the traditional land-use systems, agrobiodiversity and agrodiversity in Peru are present and linked with the climate change adaptations.
    Type of Medium: Online Resource
    Pages: XXI, 200 p. 31 illus., 30 illus. in color. , online resource.
    Edition: 1st ed. 2023.
    ISBN: 9783031443855
    DDC: 577
    Language: English
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  • 9
    Keywords: Immunology. ; Virology. ; Medicine History. ; Veterinary medicine. ; Vaccines Biotechnology. ; Biomaterials. ; Immunology. ; Virology. ; History of Medicine. ; Veterinary Science. ; Biomaterials-Vaccines.
    Description / Table of Contents: The world in flux – the Columbian Exchange D. Domenici -- Glimpses into the past: new world contributions towards understanding the basic etiology, pathobiology & treatment of rabies, Drishya Kurup et al -- The Diversity, Evolution and Emergence of Rabies Virus in the Americas, Edward C. Holmes & Erin H. Harvey -- The ecological range and principles of wildlife rabies virus perpetuation in the Americas, Amy T. Gilbert -- Historical Laboratory Contributions Supporting Rabies Diagnosis and Disease Prevention and Control in the Americas, Susan A. Nadin-Davis, et al -- Progression from nerve tissue vaccines to recombinant biologics, H. Ertl -- Wildlife Rabies Management in the New World: Prevention, Control and Elimination in Mesocarnivores, R. Chipman et al -- Management of vampire bats and rabies: past, present, and future, Tonie Rocke & Daniel Streicker -- Conflicting Perspectives on a Rabies Outbreak in a Venezuelan Rainforest, 2007-2008, C. Briggs -- Rabies, Medicine, and Culture: Dogs, Disease, and Urban Life in the United States, 1840-1920, Jessica Wang -- Historical disparities in health: rabies surveillance, risk factors and prevention, Amira Roess et al -- The Health Economics of Rabies in the Americas: An Historical Summary and a Synthesis of the Literature, S.A. Shwiff -- Towards the elimination of canine rabies in the americas: governance of a regional program, M. Vigilato et al -- Musing Over Non-technical Criticalities of Rabies Prevention and Control in the Americas, Victor J. Del Rio Vilas & Gilberto Montibeller.
    Abstract: Rabies is one of the oldest known pathogens, is incurable, and has the highest fatality rate of all infectious diseases. The Americas is the only region with bat rabies virus, including vampire bat rabies. The region is rich in cultural references and notable for many discoveries in the field, including the current vaccine potency test, diagnostic assay, conception of oral vaccines for wildlife, the first human survivor and the first successful canine rabies program executed at a broad level. Rabies remains the most important viral zoonosis, with tens of thousands of human fatalities and tens of millions of exposures annually, which can be used to model for other pathogens, such as COVID-19. There is an international effort to eliminate human rabies caused by dogs over the next decade, and the Americas represent the primary region with the greatest proof-of-concept evidence to accomplish this goal. This two-volume set addresses the medical history and modern results of rabies in countries throughout the Americas, including the implications of and on cultural, economic, sociological, and research developments in the region. Volume I presents an overview of concepts critical to the study of rabies in the region, including evolutionary aspects, reservoir ecology and control, elimination efforts, vaccine development, and disease hallmarks and progression. It also analyzes the long-term cultural, social, and economic impacts of the disease in the Americas. .
    Type of Medium: Online Resource
    Pages: XVI, 319 p. 1 illus. , online resource.
    Edition: 1st ed. 2023.
    ISBN: 9783031250521
    Series Statement: Fascinating Life Sciences,
    DDC: 571.96
    Language: English
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  • 10
    Online Resource
    Online Resource
    Cham :Springer International Publishing :
    Keywords: Biotic communities. ; Food science. ; Biodiversity. ; Environmental sciences Social aspects. ; Ecosystems. ; Food Science. ; Biodiversity. ; Environmental Social Sciences.
    Description / Table of Contents: 1. Agro-biodiversity across the food chain -- 2. Emerging risks to plant health -- 3. Future-proofing Plants against Climate Change- A path to ensure Sustainable Food Systems -- 4. The role of Integrated Pest Management for sustainable food production: The soybean example -- 5. (Alternative approaches to pesticide use): Plant-derived pesticides -- 6. Antimicrobial use in animal food production -- 7. Impacts of environment-friendly unit operations on the functional properties of bee pollen -- 8. Microbiome applications for sustainable food systems -- 9. Healthier and sustainable food systems: integrating underutilized crops in a ‘Theory of Change Approach -- 10. Alternative proteins for food and feed.
    Abstract: In recent decades, practices like the cultivation of a few high-yielding crop varieties on a large scale, the application of heavy machinery and continued mechanization of agriculture, the removal of natural habitats, and the application of pesticides and synthetics have resulted in the simplification of agro-ecosystems. This has enabled a substantial increase in food production but has at the same time transformed landscapes. Indeed, there is a concern that a decline in biodiversity has affected microbiome activities that support processes across soils, plants, animals, the marine environment, and humans. Although they have increased food production, the above practices cannot be considered sustainable in long-term applications. Biodiversity, Functional Ecosystems, and Sustainable Food Production explore ecosystems in terms of crop and animal production, pest and disease control, nutrient cycling, and soil fertility. Chapters range from agro-biodiversity to antimicrobial use in animal food production to microbiome applications for sustainable food systems and the impacts of environment-friendly unit operations on the functional properties of bee pollen. By examining such topics about each other, the text emphasizes how food production, ecosystem function, food quality, and consumer health are all interconnected.
    Type of Medium: Online Resource
    Pages: X, 354 p. 90 illus., 40 illus. in color. , online resource.
    Edition: 1st ed. 2023.
    ISBN: 9783031074349
    DDC: 577
    Language: English
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  • 11
    Online Resource
    Online Resource
    Cham :Springer International Publishing :
    Keywords: Ecology . ; Evolution (Biology). ; Ecology Methodology. ; Biodiversity. ; Biotic communities. ; Population biology. ; Ecology. ; Evolutionary Ecology. ; Ecological Modelling. ; Biodiversity. ; Community and Population Ecology.
    Description / Table of Contents: 1. Introduction. Randall W. Myster -- 2. Mountain gradients in the Neotropics, a bracken fern perspective. Jorge Luis Avila Nuñez, Maria Pia Calcagno-Pissarelli, Miguel E. Alonso-Amelot -- 3. Effects of agricultural expansion on lotic benthic macroinvertebrate communities: a review and case study from Brazil. Elaine C. Corrêa and Ryan M. Utz -- 4. Plant competition across topographic gradients in Neotropical Cerrado savannas: an isotopic approach. Davi R. Rossatto and Augusto C. Franco -- 5. Diversity of aquatic macroinvertebrates along altitudinal gradients in Colombian. Cesar E. Tamaris-Turizo, Gabriel A. Pinilla-A and Juan D. González-Trujillo -- 6. Intraspecific trait variability of emblematic grass and tree species from Venezuelan savannas across extended physical gradients. Zdravko Baruch -- 7. Latitudinal trends in scorpion assemblages of Brazilian Atlantic Forest: do the Rapoport’s and Bergmann’s rules apply? André F.A. Lira, Alessandra R.S. Andrade and Stênio I.A. Foerster -- 8. Species diversity of three faunal communities along a successional cloud forest gradient. Juan Manuel Díaz-García, Fabiola López-Barrera, Eduardo Pineda, Jorge Valenzuela-González and Adriana Sandoval-Comte -- -- 9. Ecohydrological gradient in Neotropical montane ecosystems: From tropical montane forests to glacier. Conrado Tobón, Erick Castro, and Jorge Luís Ceballos -- 10. Communities of small terrestrial arthropods change rapidly along a Costa Rican elevation gradient. M. Alex Smith, Connor Warne, Kate Pare, Sarah Dolson, Elyssa Loewen, Kelsey Jones, Megan McPhee, Lauren Stitt, Lauren Janke, Rebecca M. Smith, Heather Coatsworth, Alexandre M. M. C. Loureiro, Angel Solis, Carlos F. Viquez, Josephine Rodriguez, Jose Fernandez-Triana, Michael J. Sharkey, James Whitfield, Alejandro Masís, María Marta Chavarría, Roger Blanco, Felipe Chavarria, Eugenie Phillips-Rodríguez, Roberto Fernández, Dunia Garcia, Guillermo Pereira, Harry Ramirez, Manuel Pereira, Winnie Hallwachs and Daniel H. Janzen -- 11 Neotropical gradients of insect groups in Brazilian mountains. Lucas Neves Perillo, Frederico de Siqueira Neves, Flávio Siqueira de Castro and Ricardo Ribeiro de Castro Solar -- 12. Altitudinal Pattern of Soil Organic Carbon and Nutrients in a Tropical Forest in Puerto Rico. Dingfang Chen, Mei Yu, Grizelle González, Qiong Gao -- 13. Elevational and latitudinal species richness patterns of dung beetles in North and South America and the role played by historical factors. Jorge M. Lobo and José Gutiérrez -- 14. Diversity patterns of vascular plant groups along gradients of elevation and disturbance in Mexico. Jorge A. Gómez-Díaz, Alma P. Bautista-Bello, César I. Carvajal-Hernández, Valeria Guzmán-Jacob, María Leticia Monge-González and Thorsten Krömer -- 15 Gradients and the Structure of Neotropical Metacommunities: Effects of Disturbance -- Elevation, Landscape Structure, and Biogeography. Steven J. Presley, Michael R. Willig -- 16. Socioecological gradients: contesting traditional ecoclines to explain the high biocultural diversity of the Andean verdant. Fausto Sarmiento, Andreas Haller, Domenico Branca, Christiam Aguirre, Vladimir Kremsa, Carla Marchant, Masahito Yoshida -- 17. Conclusions, synthesis and future directions. Randall W. Myster.
    Abstract: The importance of the Neotropics to the world's climate, biogeochemical cycling and biodiversity cannot be questioned. This book suggests that gradients are key to understanding both these issues and Neotropical ecosystem structure, function and dynamics in general. Those gradients are either spatial, temporal or spatio-temporal, where many temporal and spatio-temporal gradients are initiated by disturbances (e.g., tree-fall, landslide, cultivation). And in particular for the Neotropics, three large spatial gradients - latitude, longitude, altitude (elevation) - are of critical importance. The editor has over 30 years of experience investigating Neotropical gradients in Costa Rica, Puerto Rico, Peru and Ecuador, and has published 5 previous books on different aspects of the Neotropics. Once again he has assembled top-shelf Neotropical scientists and researchers, here to focus on gradients: their nature, interactions and how they structure ecosystems.
    Type of Medium: Online Resource
    Pages: XVII, 468 p. 114 illus., 84 illus. in color. , online resource.
    Edition: 1st ed. 2023.
    ISBN: 9783031228483
    DDC: 577
    Language: English
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  • 12
    Online Resource
    Online Resource
    Cham :Springer International Publishing :
    Keywords: Immunology. ; Food science. ; Nutrition   . ; Immunology. ; Food Science. ; Nutrition.
    Abstract: Nutrition is an important environmental factor for the maturation of the human immune system and essential for maintaining immunological homeostasis. Based on this, a variety of food applications with medical claims are being generated by food manufacturers worldwide in order to expand the market potential of products creating interesting linkages with other market segments, such as cosmetics and pharmaceuticals. However, in addition to the health benefits, active principles of such components often remain unexplored. This book focusses on the specific interactions between food ingredients and the immune system along the entire immune defense response. Starting from the immune barrier, through the innate and adaptive immune response, to active limitation and termination, all major mechanisms of the immune response are addressed and different biochemical, cellular and genetic interactions of components of our diet are discussed. The book presents a wealth of disease patterns for which nutritional factors are relevant and thereby provides indications for potential intervention strategies. In addition, associated food-technological aspects are discussed. Being the first of its kind, this book provides an overview of the variety of functional food components and their influence on immunological responses. Written in an accessible style, it addresses researchers, health professionals and students with different scientific backgrounds. This book is a translation of an original German edition. The translation was done with the help of artificial intelligence (machine translation by the service DeepL.com). A subsequent human revision was done primarily in terms of content, so that the book will read stylistically differently from a conventional translation.
    Type of Medium: Online Resource
    Pages: XXIII, 241 p. 73 illus., 68 illus. in color. , online resource.
    Edition: 1st ed. 2023.
    ISBN: 9783031115233
    DDC: 571.96
    Language: English
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  • 13
    Keywords: Immunology. ; Internal medicine. ; Microbiology. ; Pharmacology. ; Immunology. ; Internal Medicine. ; Microbiology. ; Pharmacology.
    Description / Table of Contents: Genetics of sex differences in immunity -- The influence of sex hormones and X chromosome in immune responses -- Sex Differences in HIV Infection -- Chapter 6: Effects of Biological Sex and Pregnancy on SARS-CoV-2 Pathogenesis and Vaccine Outcomes -- Biological sex and pregnancy affect influenza pathogenesis and vaccination -- Sex and gender differences in tuberculosis pathogenesis and treatment outcomes -- Sex-Linked Differences in Malaria Risk Across the Lifespan -- Sex Difference in Amebiasis -- Sex Differential and Non-Specific Effects of Vaccines Over the Life Course -- Immunology of pregnancy and systemic consequences.
    Abstract: This fully revised and significantly expanded second edition examines sex and gender differences in the immune system's response to bacterial, viral, and parasitic infections. The volume discusses both common and distinct molecular mechanisms that mediate these differences and illustrates how responses to vaccines may differ between the sexes and in pregnant individuals. Special emphasis is placed on the interplay between hormones and the immune system in the pathogenesis of HIV, SARS-CoV-2, influenza, malaria, tuberculosis, and amebiasis. This second edition includes completely rewritten chapters as well as all new contents. This book is intended for researchers in academia and industry as well as clinicians in the fields of microbiology, immunology, and pharmacology. By expanding knowledge in sex and gender medicine as a basis for developing personalized treatment strategies, the book contributes to UN Sustainable Development Goals 3 (health and well-being) and 5 (gender equality).
    Type of Medium: Online Resource
    Pages: VI, 280 p. 14 illus., 13 illus. in color. , online resource.
    Edition: 2nd ed. 2023.
    ISBN: 9783031351396
    Series Statement: Current Topics in Microbiology and Immunology, 441
    DDC: 571.96
    Language: English
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  • 14
    Online Resource
    Online Resource
    Cham :Springer International Publishing :
    Keywords: Ecology . ; Biodiversity. ; Biotic communities. ; Population biology. ; Biogeography. ; Ecology. ; Biodiversity. ; Community and Population Ecology. ; Biogeosciences.
    Description / Table of Contents: Chapter 1. Introduction -- Chapter Two. Theories and Models -- Chapter 3. The Structure of Macroecological Data -- Chapter 4. Structure and Dynamics of Geographic Ranges -- Chapter 5. The Macroecological Understanding of Ecological Niches -- Chapter 6. Richness and Diversity Patterns -- Chapter 7. Macroecological Assemblages -- Chapter 8. Patterns in Body Size -- Chapter 9. From Theoretical to Applied Macroecology -- Chapter 10. Concluding Remarks. .
    Abstract: This comprehensive volume discusses the patterns and processes analyzed in macroecology with a distinct look at the theoretical and methodological issues underlying the discipline as well as deeper epistemological matters. The book serves as a synthesis of macroecological literature that has been published since Brown and Maurer proposed and defined the term “macroecology” in 1989. Author José Alexandre Felizola Diniz-Filho draws from the different disciplines and branches (ecology, evolutionary biology, physiology, behavioral sciences, climatology, and paleontology) that make up macroecology to present a full, holistic picture of where the discipline stands. Through ten chapters, Diniz-Filho moves from a discussion of what macroecology actually is to macroecological modeling to the more applied side of the discipline, covering topics such as richness and diversity patterns and patterns in body size. The book concludes with a synthesis of how macroecological research is done in a theoretical and operational sense as well as unifying explanations for each of the macroecological patterns discussed, moving on to evaluate which theories and models are still useful and which ones can be abandoned. The book is intended for academics, young researchers and students interested in macroecology and conservation biogeography. In addition, because of the integrative nature of macroecology and the theoretical and methodological background in the book, it can be of interest to researchers working in related fields including but not limited to ecology and evolutionary biology.
    Type of Medium: Online Resource
    Pages: XX, 449 p. 101 illus., 12 illus. in color. , online resource.
    Edition: 1st ed. 2023.
    ISBN: 9783031446115
    DDC: 577
    Language: English
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  • 15
    Online Resource
    Online Resource
    Cham :Springer International Publishing :
    Keywords: Immunology. ; Biology Technique. ; Biotechnology. ; Molecular biology. ; Industrial engineering. ; Production engineering. ; Immunology. ; Biological Techniques. ; Biotechnology. ; Molecular Biology. ; Industrial and Production Engineering.
    Description / Table of Contents: Chapter 1. Introduction: The Marathon of the Messenger RNA -- Part I. Messenger RNA, an essential role and challenge -- Chapter 2. A short history of vaccination -- Chapter 3. From DNA to RNA -- Chapter 4. Messenger RNA (mRNA): from transcription to protein translation -- Chapter 5. The mechanism of viral infection -- Chapter 6. The immune response -- Part II. From preliminary studies to clinical trials -- Chapter 7. Promising studies in the 1990s -- Chapter 8. The use of mRNA - the initial technical obstacles -- Chapter 9. The birth of CureVac: the era of the pioneers -- Chapter 10. Solutions for mRNA optimization -- Chapter 11. Modified and unmodified mRNA: for what purpose? -- Chapter 12. Experiments and clinical trials conducted: the power of therapeutic mRNA -- Chapter 13. Experiments and clinical trials against infectious diseases -- Chapter 14. Experiments and clinical trials against cancer -- Chapter 15. Experiments and clinical trials carried out in other therapeutic fields -- Chapter 16. Modified mRNA versus unmodified mRNA: not just a scientific issue -- Part III. The triumph of messenger RNA -- Chapter 17. A very progressive diffusion in scientific circles -- Chapter 18. The development of future biotechs in the 2010s -- Chapter 19. The importance of intellectual property and patents -- Chapter 20. 2020: the triumph of anti-Covid mRNA vaccines -- Chapter 21. mRNA, a technology of the future.
    Abstract: The Covid-19 pandemic changed the world. Indeed a real race took place worldwide between SARS-CoV-2 on the one hand and researchers on the other – especially those specializing in messenger RNA vaccines. Four years after its emergence, the pandemic is not over, but some decisive battles have been won, thanks to the great success of mRNA vaccines. The Marathon of The Messenger presents the history of these mRNA vaccines, combining a scientific background with historical and economic perspectives. It appears that an important page in the history of these new vaccines was written in Europe, thanks to the crucial work of German and French scientists; this effort began in 1993 and continues to this day. In the face of a prevailing single-mindedness, these researchers pushed through a new therapeutic concept and defined the biotechnological keys that would open the way to the production of therapeutic messenger RNA in the fight against cancer and viral infections. Written for a broad audience and accompanied by humorous cartoons, this book will appeal to anyone looking for scientific and historical answers about mRNA vaccines. Readers will discover not only the technical and scientific knowledge of how these vaccines work, but also the economic levers that were necessary to create this technology. This book has been written in collaboration with Dr. Steve Pascolo, former director of CureVac, and the RNA messenger expert Professor Chantal Pichon. It also features a preface by Dr. Pierre Meulien, former director of the European Union public-private partnership Innovative Medicines Initiative (IMI). This book is a translation of an original French edition. The translation was done with the help of artificial intelligence (machine translation by the service DeepL.com). A subsequent human revision was done primarily in terms of content, so that the book will read stylistically differently from a conventional translation.
    Type of Medium: Online Resource
    Pages: XXIII, 202 p. 44 illus., 38 illus. in color. , online resource.
    Edition: 1st ed. 2023.
    ISBN: 9783031393006
    DDC: 571.96
    Language: English
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  • 16
    Keywords: Immunology. ; Medical microbiology. ; Virology. ; Immunology. ; Medical Microbiology. ; Virology.
    Description / Table of Contents: Programmed Necrosis in Host Defense -- ZBP1/DAI-dependent Cell Death Pathways in Influenza A Virus Immunity and Pathogenesis -- Pyroptosis in Antiviral Immunity -- Manipulation of Host Cell Death Pathways by Herpes Simplex Virus -- Subversion of Programed Cell Death by Poxviruses -- Cell Killing by Reovirus: Mechanisms and Consequences -- Outcomes of RIP kinase signaling during neuroinvasive viral infection.
    Abstract: This volume provides a comprehensive review of programmed cell death pathways and their fundamental role in antiviral host defense. The book deep-dives into the molecular functions and regulation of necroptosis and discusses how viruses induce and manipulate this potent innate cellular sensing system. Initially, understanding of necroptosis emerged from studies on tumor necrosis factor (TNF) signaling that showed the key role of receptor interacting protein kinase 1 (RIPK1) in the activation of receptor interacting protein kinase 3 (RIPK3) which then phosphorylates mixed lineage kinase domain like pseudokinase (MLKL) to execute cells via plasma membrane leakage of cytosolic contents. Since its discovery, multiple facets of the RIPK3-dependent necroptotic machinery have evolved where the requirements for execution of death varies depending on the stimulus. Virus-induced necroptosis was discovered over 10 years ago in studies on murine cytomegalovirus (MCMV) where a virus-encoded inhibitor was shown to prevent the recruitment of RIPK3 (RIP3). This transformative evidence identified a novel pathway acting independent of TNF, interferon or RIPK1 that can stop virus from infecting its natural mouse host by killing off infected cells to halt replication. Over the past decade influenza A virus (IAV), herpes simplex virus (HSV) and poxvirus vaccinia (VACV) have all been shown to trigger the pathway. Herpesviruses and poxviruses also encode inhibitors of caspase-8 whose elaboration unleashes the necroptosis pathway. IAV and other RNA viruses do not encode programmed cell death inhibitors. RIPK3 is also known to induce apoptosis by recruiting RIPK1 as shown nearly a decade ago and this dual apoptosis/necroptosis induction occurs naturally during influenza A virus infection. RIPK3 is also able to induce an inflammatory response independently of programmed cell death that can predominate to drive inflammatory disease outcomes. This volume is a must-read for researchers and advanced students in immunology and virology.
    Type of Medium: Online Resource
    Pages: V, 174 p. 19 illus., 18 illus. in color. , online resource.
    Edition: 1st ed. 2023.
    ISBN: 9783031452789
    Series Statement: Current Topics in Microbiology and Immunology, 442
    DDC: 571.96
    Language: English
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  • 17
    Keywords: Ecology . ; Freshwater ecology. ; Marine ecology. ; Pollution. ; Biotic communities. ; Population biology. ; Ecology. ; Freshwater and Marine Ecology. ; Pollution. ; Community and Population Ecology. ; Ecosystems.
    Abstract: The book provides for the first time an overview of the latest scientific studies conducted on micro and nano plastic pollution in the Mediterranean Sea both from the biological and environmental point of view as well as from the chemical point of view in order to have a more real idea of the current situation.
    Type of Medium: Online Resource
    Pages: XII, 109 p. 1 illus. , online resource.
    Edition: 1st ed. 2023.
    ISBN: 9783031304811
    Series Statement: SpringerBriefs in Environmental Science,
    DDC: 577
    Language: English
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  • 18
    Online Resource
    Online Resource
    Cham :Springer International Publishing :
    Keywords: Immunology. ; Autoimmunity. ; Inflammation. ; Immunogenetics. ; Tumors Immunological aspects. ; Immunology. ; Translational Immunology. ; Autoimmunity. ; Inflammation. ; Immunogenetics. ; Tumour Immunology.
    Description / Table of Contents: 1 Cells and tissues of the immune system -- 2 Innate immunity and inflammation -- 3 Adaptive immunity and antigen receptor diversity -- 4 B cell immunity: BCRs, antibodies and their effector functions -- 5 Antigen-presenting cells and the major histocompatibility complex -- 6 T cell immunity: TCRs and their effector functions -- 7 Immunity to bacterial pathogens and the microbiome -- 8 Immunity to viral pathogens and the virome -- 9 Tolerance and transplantation immunology -- 10 Immunological hypersensitivities: Allergy and autoimmunity -- 11 Cancer immunology.
    Abstract: This textbook aims to describe in a condensed form the essentials of molecular immunology behind bacterial infections, the microbiome, viral infections (such as influenza and COVID-19), organ transplantations, autoimmunity, allergy and tumor immunology. The book emphasizes the impact of immunology in maintaining our health and preventing disease. Our immune system protects us not only from severe consequences of infectious diseases and getting cancer, but is also able to harm us severely via sepsis, cytokine storms and anaphylactic shocks. Molecular understanding of immunology should allow the reader a more rational handling of common diseases, most of which are associated with chronic inflammation.
    Type of Medium: Online Resource
    Pages: XV, 219 p. 94 illus., 93 illus. in color. , online resource.
    Edition: 1st ed. 2022.
    ISBN: 9783031040252
    DDC: 571.96
    Language: English
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  • 19
    Online Resource
    Online Resource
    Cham :Springer International Publishing :
    Keywords: Ecology . ; Parasitology. ; Conservation biology. ; Environment. ; Applied ecology. ; Ecology. ; Parasitology. ; Conservation Biology. ; Conservation Biology. ; Environmental Sciences. ; Applied Ecology.
    Abstract: This book provides, for the first time, a comprehensive overview of the fundamental roles that ecological interactions play in extinction processes, bringing to light an underground of hidden pathways leading to the same dark place: biodiversity loss. We are in the midst of the sixth mass extinction. We see species declining and vanishing one after another. Poached rhinos, dolphins and whales slaughtered, pandas surviving only in captivity are strong emotional testimonials of what is happening. Yet, the main threat to natural communities may be overshadowed by the disappearance of large species, with most extinctions happening unnoticed and involving less eye-catching organisms, such as parasites and pollinators. Ecosystems hide countless, invisible wires connecting organisms in dense networks of ecological interactions. Through these networks, perturbations can propagate from one species to another, producing unpredictable effects. In worst case scenarios, the loss of one species might doom many others to extinction. Ecologists now consider such mechanisms as a fundamental – and still poorly understood - driver of the ongoing biodiversity crisis. Hidden Pathways to Extinction makes the invisible links connecting the fates of species and organisms evident, exploring why complexity can enhance ecosystem stability and yet accelerate species loss. Page after page, Strona provides convincing evidence that we are primarily responsible for the fall in biodiversity, that we are falling too, and that we need to redouble our conservation efforts now, or it won't be long before we hit the ground.
    Type of Medium: Online Resource
    Pages: IX, 237 p. 88 illus., 51 illus. in color. , online resource.
    Edition: 1st ed. 2022.
    ISBN: 9783030867645
    Series Statement: Fascinating Life Sciences,
    DDC: 577
    Language: English
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  • 20
    Keywords: Ecology . ; Sustainability. ; Environmental sciences Social aspects. ; Ecology. ; Sustainability. ; Environmental Social Sciences.
    Description / Table of Contents: 1 General Introduction -- 2 Peace Ecology in the Anthropocene for Africa -- 3 Civil Society, Climate Change, Security Risks Management and Peacebuilding in the Anthropocene -- 4 Faith-based Organisations and Environmental Peace: Impact of Laudato Si’ and Its Relevance in the Anthropocene -- 5 Healing Nature and Creation in the Anthropocene: A Reflection on the Role of Religion -- 6 Empowering Women to Build Peace: A Case Study of Grace to Heal Trust in Lupane District -- 7 Peacebuilding through Indigenous Knowledge Systems: Lessons from Civil Society Organisations in Zimbabwe -- 8 Civil Society and Peacebuilding in the Kivu Provinces of the Democratic Republic of Congo -- 9 Zimbabwe’s National Peace and Reconciliation Commission and Civil Society: Partners in Peacebuilding? -- 10 Civil Society and Peacebuilding in the Democratic Republic of Congo: Opportunities, Challenges and Recommendations -- 11 Promoting Democratisation in DR Congo: The Case Study of Act for Transparent and Peaceful Elections -- 12 Civil Society Organisations and School Peace Clubs in South Africa: An Outcome Evaluation -- 13 The Challenges and Opportunities for Civil Society in Peacebuilding: Lessons from the Matabeleland Collective, Zimbabwe -- 14 The Role of Civil Society Participation in Social Cohesion Processes in KwaZulu-Natal, South Africa.-15 Building the Capacity of Civil Society Organisations in Nonviolent Campaigning: A Case Study from South Sudan -- 16 How Informal Peace Committees Complement Macro-infrastructures for Peace in Zimbabwe -- 17 Protecting and Nurturing Children Born from Rape in South Kivu Communities: A Challenge for Civil Society -- 18 Indigenous Peacebuilding Approaches and the Accountability of Former Child Soldiers: African Case Studies -- 19 Navigating Channels for Civil Society Participation in Conflict Prevention and Peace-Making in the African Peace & Security Architecture -- 20 Centre-periphery Relations Between Civil Society Organisations and External Funding Partners: A Case Study of South Kivu’s Peace and Development Agenda. .
    Abstract: This book examines civil society's peacebuilding role in sub-Saharan Africa in the context of climate change and the pursuit of environmental peace and justice in the Anthropocene. Five main research themes emerge from its 20 chapters: · The roles of environmental peacemaking, environmental justice, ecological education and eco-ethics in helping to mitigate the impacts of climate change · Peacebuilding by CSOs after violent conflicts, with particular reference to accountability, reconciliation and healing · CSO involvement in democratic processes and political transition after violent conflicts · Relationships between local CSOs and their foreign funders and the interactions between CSOs and the African Union's peace and security architecture. · The particular role of faith-based CSOs The book underlines the centrality of dialogue to African peacebuilding and the indigenous wisdom and philosophies on which it is based. Such wisdom will be a key resource in confronting the existential challenges of the Anthropocene. The book will be a significant resource for researchers, academics and policymakers concerned with the challenge of climate change, its interactions with armed conflict and the peacebuilding role of CSOs. · This pathbreaking book shows why peacebuilding analysis and efforts need to be urgently re-oriented towards the existential challenges of environmental peace and justice. · It explains the emerging conceptual frameworks which are needed for this new role. · It explains the critical role that CSOs - local and international - will play in implementing this new peacebuilding approach, with particular reference to sub- Saharan Africa.
    Type of Medium: Online Resource
    Pages: XXXVI, 580 p. 43 illus., 40 illus. in color. , online resource.
    Edition: 1st ed. 2022.
    ISBN: 9783030951795
    Series Statement: The Anthropocene: Politik—Economics—Society—Science, 34
    DDC: 577
    Language: English
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  • 21
    Online Resource
    Online Resource
    Cham :Springer International Publishing :
    Keywords: Tumors Immunological aspects. ; Cancer Treatment. ; Oncology. ; Tumour Immunology. ; Cancer Therapy. ; Oncology.
    Description / Table of Contents: Chapter 1: Cancer immunoediting - elimination, equilibrium and immune escape in solid tumors -- Chapter 2: Tumor – Stroma Interaction and Cancer. - Chapter 3: Tumor-infiltrating lymphocytes and their role in solid tumor progression -- Chapter 4: Tumor-associated macrophages – reasons to be cheerful, reasons to be fearful -- Chapter 5: Polymorphonuclear neutrophils and tumors: friend or foe? -- Chapter 6: Role of NK cells in tumor progression -- Chapter 7: The role of myeloid-derived suppressor cells in tumor growth and metastasis -- Chapter 8: Cancer stem cells – an ever hiding foe -- Chapter 9: Adoptive T-cell immunotherapy – Perfecting self-defenses -- Chapter 10: Monoclonal antibodies to CTLA-4 with focus on ipilimumab.
    Abstract: Now, it its second edition, this book summarizes the role of immune cells in tumor suppression and progression. It describes in detail why tumor cells can survive and spread in spite of the antitumor response of immune cells. Since immunotherapy is an attractive approach to cancer therapy, this book also provides information on the two main strategies: monoclonal antibodies and adaptive T cell immunotherapy, with a focus on recent human clinical trials. A newly added chapter also focuses on the role of Natural Killer cells in tumor progression. The book provides a state-of-the-art, comprehensive overview of immune cells in cancer and is an indispensable resource for researchers and practitioners working or lecturing in the field of cancer research and immunology.
    Type of Medium: Online Resource
    Pages: XIV, 350 p. 22 illus., 20 illus. in color. , online resource.
    Edition: 2nd ed. 2022.
    ISBN: 9783030913113
    Series Statement: Experientia Supplementum, 113
    DDC: 571.96
    Language: English
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  • 22
    Online Resource
    Online Resource
    Cham :Springer International Publishing :
    Keywords: Ecology . ; Landscape ecology. ; Plant ecology. ; Ecology. ; Landscape Ecology. ; Plant Ecology. ; Terrestial Ecology.
    Description / Table of Contents: Chap 1: Disturbance ecology: a guideline -- Chap 2: Definitions and quantifications -- Chap 3: Concepts -- Chap 4: Abiotic disturbances -- Chap 5: Biotic disturbances -- Chap 6: Anthropogenic disturbances -- Chap 7: Disturbances in global change -- Chap 8: Disturbances and management.
    Abstract: This edited work presents a multi-faceted view on the causes and consequences of disturbance in ecosystems. Vegetation can be affected by a variety of different disturbances such as wind, floods, fire, and insect attack, leading to an abrupt change in live biomass. Disturbance is a motor of vegetation dynamics, but also sensitive to climate change and poses a challenge for ecosystem management. Readers will discover the global distribution of disturbance regimes and learn about the importance of disturbances for biodiversity and the evolution of plant and animal life. The book provides a Central European perspective on disturbance ecology, and addresses important disturbance agents such as fire, wind, avalanches, tree diseases, insect defoliators, bark beetles and large herbivores in dedicated chapters. It furthermore includes chapters on anthropogenic disturbances in forests and grasslands. The impact of climate change on disturbance regimes and approaches to address disturbance risks in ecosystem management are discussed in concluding chapters. Within the 18 chapters 14 textboxes highlight current topics of disturbance ecology and provide deeper methodological insights into the field. Disturbances strongly shape our landscapes and maintain our biodiversity. A better understanding of their ecology is thus fundamental for contextualizing the dynamic changes in our environment. This book is a valuable resource for students and practitioners interested in disturbances and their management.
    Type of Medium: Online Resource
    Pages: XI, 439 p. 153 illus. in color. , online resource.
    Edition: 1st ed. 2022.
    ISBN: 9783030987565
    Series Statement: Landscape Series, 32
    DDC: 577
    Language: English
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  • 23
    Keywords: Immunology. ; Human physiology. ; Pathology. ; Immunology. ; Human Physiology. ; Pathology.
    Description / Table of Contents: Overview of Immune response -- Metabolic Pathway: from biochemistry to bench -- Mitochondrial biogenesis and dynamics in healthy and diseases -- Epigenetic regulation of metabolic pathways -- Metabolic pathways and cells signaling -- Metabolic profile of innate and adaptive immune cells -- Metabolic sensors and immunopathology -- Obesity, metabolic syndrome and inflammation.
    Abstract: Immunometabolism has emerged as an intersectional crossroad between metabolism and immune response. Over the past decade, it has become clear that most - if not all - immune cell functions are not separated from cellular metabolism. Although seminal works have addressed the metabolic fate of immune cells during differentiation and function, the physiological status of a given tissue is also dependent on the cell metabolism. The dialogue between immune cells and their microenvironment can also modulate cellular metabolism, which can trigger the onset and progression of a multitude of inflammation-mediated diseases. Thus, uncovering the specific characteristics of the metabolism in different immune cells types and in different conditions, can shed light into the molecular mechanisms of disease and help develop new drugs and therapeutic strategies to treat immune diseases. The edited volume Essentials aspects of Immunometabolism will give the readers a broad view on how metabolic pathways can influence many types of immune cells during activation, differentiation and function, in health and disease. Of note, the structure of the book was created thinking not only on the experienced immunologist but also on undergraduate and graduate students, physicians, and all members of the scientific community interested in this exciting field of research.
    Type of Medium: Online Resource
    Pages: XII, 278 p. 38 illus., 37 illus. in color. , online resource.
    Edition: 1st ed. 2022.
    ISBN: 9783030866846
    DDC: 571.96
    Language: English
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  • 24
    Keywords: Immunology. ; Immune response. ; Pathogenic microorganisms. ; Natural immunity. ; Biotechnology. ; Immunology. ; Antimicrobial Responses. ; Innate Immunity. ; Biotechnology.
    Description / Table of Contents: 1. Antimicrobials in livestock production and its cross-domain dynamics -- 2. Antibiotics and resistance in environment -- 3. Antimicrobials in agriculture and its implications in antimicrobial resistance -- 4. Modern diagnostic tools for rapid detection of multidrug resistance -- 5. The use of antimicrobials in agriculture and socio-economic considerations in a global world -- 6. Epidemiology of microbial infections -- 7. Socioeconomic impact of antimicrobial resistance and their integrated mitigation by One Health approach -- 8. Regulations in antimicrobial drug development: Challenges, and new incentives -- 9. New insights into and updates on antimicrobial agents -- 10. Polyphenols as emerging antimicrobial agents -- 11. Antimicrobial peptides and small molecules as antibiotics substitute -- 12. Molecular mechanisms of antimicrobial resistance in S. aureus biofilms -- 13. Antimicrobial resistance: Meaning and developing realization -- 14. Chemical diversity in fungi: strategies to mitigate antimicrobial resistance -- 15. Phage therapy as an alternative treatment in the fight against AMR: Real-world problems and possible futures -- 16. Omics and in-silico approaches in the surveillance and monitoring of antimicrobial resistance -- 17. Antimicrobial activity of bioactive compounds (Thymoquinone & Eugenol) and its nanoformulations therapeutic potential -- 18. Nanoparticles as a future alternative against multiple drug resistance -- 19. Nano-cargos boarded defensins to combat multi-drug resistance -- 20. Implementation of nano-vehicles to disguise and fight multi-drug resistance -- 21. Silver nanoparticles as potent multi-drug resistant in-corporants in biomedicine -- 22. Role of gold nanoparticles against bacterial multidrug resistance (MDR): An emerging therapeutic revolution -- 23. Carbon nanoparticles: A potential cost-effective approach to counter antimicrobial resistance -- 24. Antimicrobial interfaces as augmentative strategy against antimicrobial resistance -- 25. Nano-Strategies against rising antimicrobial resistance (AMR): Metallic nanoparticles as nano-weapon. .
    Abstract: This book provides an overview of cutting-edge and next-generation research and technologies for combating antimicrobial resistance. Antibiotic-resistant infections are projected to cause 10 million deaths annually by the year 2050. A sustainable, unified approach by researchers, practitioners, policymakers, and the public is urgently needed to stem this trend. This book aims to provide a comprehensive summary of current and future-facing efforts to mitigate the threat of AMR through a One-Health approach. This book is a valuable resource for students, researchers, policymakers, and the public about AMR and novel strategies to combat AMR.
    Type of Medium: Online Resource
    Pages: XII, 577 p. 62 illus. in color. , online resource.
    Edition: 1st ed. 2022.
    ISBN: 9783030841263
    DDC: 571.96
    Language: English
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  • 25
    Online Resource
    Online Resource
    Cham :Springer International Publishing :
    Keywords: Immunology. ; Pharmacology. ; Virology. ; Immunology. ; Pharmacology. ; Virology.
    Description / Table of Contents: Preface -- Molecular Virology of Chikungunya Virus -- Understanding molecular pathogenesis with chikungunya virus research tools -- Chronic Chikungunya Virus Disease -- Chikungunya Virus Vaccines: Platforms, Progress, and Challenges -- Small Molecule Inhibitors Targeting Chikungunya Virus.
    Abstract: This book provides readers with a collection of latest reviews written by Chikungunya virus (CHIKV) research leaders who cover topics related to CHIKV replication, advances in CHIKV research reagents and model system development, as well as the pathogenesis of chronic CHIKV disease. Moreover, the volume updates on recent progress in the development of therapeutics and vaccines for treatment and prevention of CHIKV-induced disease. Chikungunya virus (CHIKV) is a mosquito-borne pathogen that has re-emerged to become a significant global disease threat. Although CHIKV has historically been associated with localized outbreaks of debilitating polyarthralgia in Africa and Asia, factors such as increased global travel and viral adaptation to new mosquito vectors have led to the introduction and spread of CHIKV in new regions of the world, including the Americas. The re-emergence of CHIKV has stimulated significant interest both in understanding the biology of CHIKV and in the development of medical countermeasures against the virus.
    Type of Medium: Online Resource
    Pages: XI, 139 p. 10 illus., 7 illus. in color. , online resource.
    Edition: 1st ed. 2022.
    ISBN: 9783030906108
    Series Statement: Current Topics in Microbiology and Immunology, 435
    DDC: 571.96
    Language: English
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  • 26
    Keywords: Immunology. ; Inflammation. ; Autoimmunity. ; Allergy. ; Immunology. ; Inflammation. ; Autoimmunity. ; Allergology.
    Description / Table of Contents: Chapter 1. From observing children in traditional upbringing to concepts of health -- Chapter 2. Human evolution, microorganisms, socioeconomic status and reconciling necessary microbial exposures with essential hygiene -- Chapter 3. Biodiversity, microbiomes, and human health -- Chapter 4. Regulation of host immunity by the gut microbiota -- Chapter 5. The gut microbiota and host metabolism -- Chapter 6. The impacts of the microbiota on animal development and physiology -- Chapter 7. The development of the gut microbiota in childhood, and its distortion by lifestyle changes -- Chapter 8. Distortion of the microbiota of the natural environment by human activities -- Chapter 9. The nature and functions of vertebrate skin microbiota -- Chapter 10. The influence of the microbiota on brain structure and function: Implications for stress-related neuropsychiatric disorders -- Chapter 11. Neurodegenerative diseases and the gut microbiota -- Chapter 12. Clinical application of the biodiversity hypothesis in the management of allergic disorders. .
    Abstract: This edited collection of 12 chapters by research workers from a wide range of disciplines resolves the confusion that currently surrounds the “hygiene hypothesis” by considering the human need for exposure to microorganisms from an evolutionary point of view. The book explains why we evolved a requirement for exposure to microbiota from our mothers, from other people, and from the natural environment. It also explains the physiological roles of these exposures, what goes wrong when the exposures are distorted and how human lifestyles and activities, including degradation of the natural environment, are leading to this distortion. Particular attention is given to the range of pathologies associated with inappropriate microbial exposures and inappropriate colonization, including immunoregulatory problems such as allergies and autoimmunity, metabolic problems such as obesity and diabetes, and problems of central nervous system function and neurodegeneration. This book is of profound relevance to most medical disciplines, but also to those concerned with preserving the natural environment and with developing healthier urbanisation.
    Type of Medium: Online Resource
    Pages: X, 414 p. 46 illus., 45 illus. in color. , online resource.
    Edition: 1st ed. 2022.
    ISBN: 9783030910518
    Series Statement: Progress in Inflammation Research, 89
    DDC: 571.96
    Language: English
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  • 27
    Online Resource
    Online Resource
    Cham :Springer International Publishing :
    Keywords: Immunology. ; Pharmacology. ; Internal medicine. ; Clinical biochemistry. ; Immunology. ; Pharmacology. ; Internal Medicine. ; Medical Biochemistry.
    Description / Table of Contents: Preface -- mRNA-based vaccines and mode of action -- Self-Amplifying mRNA-Based Vaccine Technology and its Mode of Action -- Formulation and Delivery Technologies for mRNA Vaccines -- Messenger RNA-based vaccines against infectious diseases -- Emerge gate for Therapeutics applications of mRNA based drug -- Clinical Development of mRNA Vaccines: Challenges and Opportunities -- Regulatory Considerations on the Development of mRNA Vaccines.
    Abstract: The formulation and the technological advancements in RNA biology, chemistry, stability, and encapsulated delivery systems that have enabled the development of fully synthetic mRNA vaccines are discussed in this volume. The applications of the mRNA technology is covered, focusing on infectious diseases but also touching on other indications, such as immunotherapies and molecular therapies. Potent and long-lasting immune responses observed in animal models, encouraging data from early human clinical studies, together with the success of two mRNA-based COVID-19 vaccines support the use of mRNA-based vaccination as an attractive alternative to conventional vaccine approaches. Consequently, the development progress of the technology, particularly on production, capabilities, and clinical development is reviewed. Topics on safety, regulatory issues, and possible challenges to the mRNA vaccination approach round off this book. Thanks to their high potency, the prospect for generic, low-cost manufacturing processes, and entirely synthetic nature, the future for mRNA vaccines is highly promising. Importantly, mRNA vaccines have the potential to minimize the time between pathogen identification and vaccine release with a huge impact on public health. As the mRNA-based vaccination technology has been progressing rapidly, the book is intended to be an end-to-end review series, covering everything from basic RNA biology and preclinical studies to the manufacturing strategy, clinical development and regulatory approval. It provides established RNA researchers and developers with updates on the latest advancements in the field and allows for a quick but comprehensive overview of this transformative technology, its application, and future potential.
    Type of Medium: Online Resource
    Pages: XI, 205 p. 8 illus., 7 illus. in color. , online resource.
    Edition: 1st ed. 2022.
    ISBN: 9783031180705
    Series Statement: Current Topics in Microbiology and Immunology, 437
    DDC: 571.96
    Language: English
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    Keywords: Biotic communities. ; Biodiversity. ; Geography. ; Environmental management. ; Ecosystems. ; Biodiversity. ; Regional Geography. ; Environmental Management.
    Description / Table of Contents: Part I: Conceptualizing human-nature interactions -- Chapter 1. Conceptualizing human-nature interactions – an overview -- Chapter 2. Environmental Values and Nature’s Contributions to People: Towards methodological pluralism in evaluation of sustainable ecosystem services -- Chapter 3. Disentangling trade-offs between the state of coastal ecosystems with human well-being and activities as a strategy addressing sustainable tourism -- Chapter 4. From human-nature dualism towards more integration in socio-ecosystems studies -- Chapter 5. A network approach to Green Infrastructure: how to enhance ecosystem services provision? -- Chapter 6. Transformations of urban coastal nature(s): Meanings and paradoxes of Blue Urbanism and nature-based solutions for climate adaptation in Southeast Asia -- Part II: Mountain systems -- Chapter 7. Values of mountain landscapes: Insights about the Blue Mountains National Park, Australia from Twitter -- Chapter 8. Earth observations of human-nature interactions from a cultural ecosystem service perspective -- Chapter 9. Gendered Values, Roles, and Challenges for Sustainable Provision of Forest-based Ecosystem Services in Nepal -- Chapter 10. Environmental [in]equity: Accessibility to green spaces in a rapidly urbanizing mountain-city -- Chapter 11. Ecosystem services and sustainable development in the European Alps: spatial patterns and mountain-lowland relationships -- Chapter 12. Human-nature relationships for the Flathead Wild and Scenic River System: Analyzing diversity, synergies, and tensions in a mountainous region of Montana, USA -- Chapter 13. Resilience and sustainability of the Maloti-Drakensberg mountain system: a case study on the upper uThukela catchment -- Chapter 14. Invasive alien plants in the montane areas of South Africa: impacts and management options -- Part III: Urban systems -- Chapter 15. Ecosystem service flows across the rural-urban spectrum -- Chapter 16. A typology for green infrastructure planning to enhance multifunctionality incorporating peri-urban agricultural land -- Chapter 17. Urban green spaces in a post-apartheid city: challenges and opportunities for nature-based solutions -- Chapter 18. Green infrastructure and ecosystem services within spatial structure of city – examples from Poznań, Poland -- Chapter 19. Accessibility to and fragmentation of urban green infrastructure: importance for adaptation to climate change -- Chapter 20. Social Demand for Urban Wilderness in Purgatory -- Chapter 21. The Role of Allotment Gardens for Connecting Nature and People -- Chapter 22. Green spaces and their social functions: specific challenges in urban spaces of arrival -- Chapter 23. The link between urban green space planning tools and distributive, procedural and recognition justice -- Part IV: Coastal-marine systems -- Chapter 24. Can local knowledge of Small-scale fishers be used to monitor and assess changes in marine ecosystems in a European context? -- Chapter 25. Marine ecological democracy: participatory marine planning in Indigenous marine areas in Chile -- Chapter 26. The Socio-Ecological Dimension of Ocean Multi-Use -- Chapter 27. Localizing the Sustainable Development Goals for marine and coastal management in Norway: A venture overdue -- Chapter 28. Coastal-Marine ecosystem accounting to support Integrated Coastal Zone Management -- Chapter 29. Exposure of coastal ecosystem services to natural hazards in the Bangladesh coast -- Chapter 30. Adaptations to climate variability in fisheries and aquaculture social-ecological systems in the Northern Humboldt Current Ecosystem: challenges and solutions -- Chapter 31. Socio-Ecological transformations in coastal wetlands: an approach from the south-central zone of Chile -- Chapter 32. A Nature-based Solution for coastal foredune restoration: The Case Study of Maghery, County Donegal, Ireland.
    Abstract: This edited volume aims to widen the discussion about the diversity of human-nature relationships and valuation methods and to stimulate new perspective that are needed to build a more sustainable future, especially in face of ongoing socio-environmental changes. Conceptual and empirical approaches, including qualitative, quantitative, and mixed methodologies have been used to highlight the importance of an integrative understanding of socio-ecological systems, where healthy ecosystems underpin the quality of life and societal activities largely drive environmental changes. Readers will obtain a comprehensive overview of the many and diverse ways the relationships between people and nature can be characterized. This includes understanding how people assign values to nature, discuss how human-nature interactions are shaped and provide examples of how these values and interactions can be systematically assessed across different land systems in Europe and beyond. This open access book is produced by internationally recognized scientists in the field but written in an accessible format to be of interest to a large audience, including prospective students, lecturers, young professionals and scientists embarking to the interdisciplinary field of socio-ecological research and environmental valuation.
    Type of Medium: Online Resource
    Pages: XVIII, 438 p. 1 illus. , online resource.
    Edition: 1st ed. 2022.
    ISBN: 9783031019807
    DDC: 577
    Language: English
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    Online Resource
    Online Resource
    Cham :Springer International Publishing :
    Keywords: Immunology. ; Aging. ; Neurosciences. ; Nutrition   . ; Medical sciences. ; Immunology. ; Ageing. ; Neuroscience. ; Nutrition. ; Health Sciences.
    Description / Table of Contents: Introduction -- Changes in primary and secondary lymphoid organs (bone marrow, thymus, lymph nodes, spleen) -- Immune barriers (skin, mucosa) -- Innate immunity (neutrophils, monocytes, macrophages) -- Adaptive immunity (T and B lymphocytes: naïve, effector and memory phenotypes and functions) -- ReIntroduction -- Changes in primary and secondary lymphoid organs (bone marrow, thymus, lymph nodes, spleen) -- Immune barriers (skin, mucosa) -- Innate immunity (neutrophils, monocytes, macrophages) -- Adaptive immunity (T and B lymphocytes: naïve, effector and memory phenotypes and functions) -- Regulatory/suppressive cells (Treg, MDSC) -- Infections - Flu, pneumonia, COVID -- Vaccine responses -- Cancer -- Neurodegenerative disease -- Lifestyle/Interventions(physical activity, nutrition, supplements). .
    Abstract: This book presents studies of the main conditions that affect health and well-being of old people. Considering the present scenario of COVID-19, the effects of this viral infection on individuals older than 65 years are also discussed. The content enables professionals of health and government for the present and future actions in this important area. Readers go through the changes occurring in organs and tissues that can interfere with susceptibility to infections, low response to vaccines, cancer, and loss of cognition during the aging process. A discussion of the central role played by the immune system in the age-related diseases and how the immunity can be impaired during the ageing process is presented. Possibilities to circumvent these conditions via healthy habits in diet, physical exercise, and new pharmacological interventions are part of the content. This book discusses how human healthy longevity is dependent, at least in part, of a functional immune system. Chapters were written for researchers in the field of aging and is especially suited for those interested in the study of immunosenescence and inflammaging affecting the health of old individuals.
    Type of Medium: Online Resource
    Pages: X, 199 p. 10 illus., 6 illus. in color. , online resource.
    Edition: 1st ed. 2022.
    ISBN: 9783030875329
    Series Statement: Healthy Ageing and Longevity, 16
    DDC: 571.96
    Language: English
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  • 30
    Keywords: Ecology . ; Evolution (Biology). ; Ecology Methodology. ; Agriculture. ; Thermodynamics. ; Conservation biology. ; Evolutionary Ecology. ; Ecological Modelling. ; Agriculture. ; Evolutionary Biology. ; Thermodynamics. ; Conservation Biology.
    Description / Table of Contents: C ontents -- Part 1. Theory -- To Understand Economics, Follow the Money: To Understand Ecosystems, Follow the Energy -- Two Views of Ecology, Evolution, and Conservation -- Why I Wrote this Book -- Dualities Still Impede Conservation Efforts -- The Intergovernmental Science-Policy Platform of Biodiversity -- Targets for Conservation -- Evolving Objectives -- Literature Review -- Updating Ecosystem Ecology -- References -- What Can We Learn by Studying Ecosystems that We Can’t Learn from Studying Populations? -- The Predator-Prey Conundrum -- The Serengeti Ecosystem -- Evolution in the “Ecological Theater” -- Predator-Prey Interactions Tell Only Part of the Story -- Evolution in the “Thermodynamic Theater” -- References -- A Thermodynamic Definition of Ecosystems -- Ecosystems in the 20th Century -- Cycling of Strontium-90 -- Cesium-137 in Food Chains -- Recycling of Isotopes in Norwegian Sheep -- Ecological Energetics -- Is it Time to Bury the Ecosystem Concept? -- A Thermodynamic Definition of Life -- A Thermodynamic Definition of Ecosystems -- The Phase Transition between Order and Chaos -- References -- Thermodynamic Characteristics of Ecosystems -- Equilibrium -- The Equilibrium Law -- Thermodynamic Equilibrium -- Open Thermodynamic Systems -- Ecosystems are Thermodynamically Open Non-Equilibrium Systems -- Work is Performed by Non-equilibrium Systems -- Advantage of a Thermodynamically Open System -- 4.3 Ecosystems are Entropic -- 4.4 Ecosystems are Cybernetic -- Cybernetic Systems -- Economic Systems are Cybernetic Ecosystems are Cybernetic -- The Ecosystem Feedback Function -- Indirect vs. Direct Feedback -- Deviation Dampening and Amplifying Feedback -- Set Points -- Ecosystems are Autocatalytic -- Ecosystems have Boundaries -- Ecosystems are Hierarchical -- Hierarchy in Physical Systems -- Hierarchy in Ecological Systems -- Common Currencies -- Macro-and Micro-System Models -- Why an Ecosystem Model that Includes Everything is not Possible -- A Nested Marine Community -- Ecosystems are Deterministic -- Ecosystems are Information Rich -- An Engineering Definition of Information -- Information to Facilitate Exchange -- High Energy Information -- Low Energy Information -- Information Theory -- Genetic Information -- Ecosystems are Non-Teleological -- Criticisms of Ecosystem Models -- References -- Ecosystem Control: A Top-Down View -- Two Ways to Look at Systems -- Composing and Decomposing Trophic Webs -- Decomposers in Soil Organic Matter -- Decomposers in Marshes and Mangroves -- Control of Systems -- Top-Down vs. Bottom-Up -- Top-Down Exogenous Control -- Exogenous Impacts and Stability -- Top-Down Endogenous Control -- Endogenous Control through Nutrient Recycling -- Autocatalysis -- Control of Microbial Activity -- Inhibition of Microbial Activity by Leaf Sclerophylly -- Inhibition of Microbial Activity Chemical Defenses -- Inhibition of Microbial Activity by Ecological Stoichiometry -- The Synchrony Principle -- The Decay Law -- Direct Nutrient Cycling -- The Role of Animals -- Indirect Interactions -- Marine Systems -- Nutrient and Energy Recycling -- Exogenous Control -- Control in Lakes -- Control in Managed Ecosystems -- References -- Ecosystem Control: A Bottom-Up View -- Species as Arbitrageurs of Energy -- Relation Between Rate of Flow and Mass in Hydraulic Systems -- Relation Between Population Biomass and Rate of Energy Flow -- Equilibrium -- Mechanisms of Adjustment -- Adjustments and Climate Change -- Bird Populations -- Dis-equilibrium -- Population Instability vs. Ecosystem Instability -- Control by Interactions: Direct vs. Indirect -- Indirect Interactions -- Direct Interactions -- Predator – Prey -- Mutualisms -- Competition -- Decomposition -- Parasitism and Disease -- Commensalism and Amensalism -- Persistence of Negative Interactions -- References -- Ecosystem Stability -- Background -- A Thermodynamic Definition -- Regime Shift -- Metastability -- Pulsed Stability -- Resistance and Resilience -- Species Richness and Functional Stability -- Species Richness and Cultural Values -- Keystone Species, and Population and Ecosystem Stability -- 7.5.1 Keystone Species in the Yellowstone region of Wyoming -- References -- 8. Case Studies of Ecosystem Control and Stability -- Walden -- “Harmony in Nature” -- Feedback Produces Nature’s “Harmony” -- Feedback Mechanisms -- Perturbations in Amazon Rain Forests -- Top-Down Control -- The San Carlos Project: A Small-scale, Low Intensity, Short Duration Disturbance -- 8.3.2 The Jarí Project: A Large-scale, High Intensity, Long Duration Disturbance -- Bottom-Up Control -- The El Verde Project -- The Long-Term Ecological Research Project in Puerto Rico -- The Lago Guri Island Project -- The Biological Dynamics of Tropical Rainforest Fragments Project -- What have Case Studies Taught us about Stability of Tropical Ecosystems? -- Tropical Ecosystems are Stable -- Tropical Ecosystems are Unstable -- Energy Flow in Tropical Savannas and Rain Forests -- Insects in Tropical Ecosystems -- Application of Lessons to Other Regions -- Relevance to Temperate Zones -- Relevance to Aquatic Ecosystems -- The Experimental Lakes Project (Ecosystem Control of Species) -- Lake Mendota Studies (Species Control of Ecosystems) -- 8.7 Case Studies as Tests of Thermodynamic Theory -- References -- Entropy and Maximum Power -- Entropy -- 9.2 Entropy in a Steel Bar -- Thermodynamic Equilibrium -- Entropic Gradients -- Capturing and Storing Entropy -- Evapotranspiration and Entropy Reduction -- Life is a Balance between Storing and Releasing Entropy -- The Law of Maximum Entropy Production -- Energy for Metabolism as well as Growth -- Unassisted Entropy Capture is a Unique Characteristic of Life.-9.6Entropy Storage by Ecosystems -- 9.6.1 What Causes Entropy to be Stored? -- 9.7 Capturing Pressure -- 9.8 Entropy and Time -- 9.8.1 Time’s Speed Regulator -- Efficiency of Energy Transformations -- Passage of Time for Cats -- 9.9The Maximum Power Principle.-9.10 Optimum Efficiencies for a Truck and its Driver.-9.11 Sustainability -- References -- A Thermodynamic View of Succession -- 10.1 The Population View -- 10.2 The Thermodynamic View -- 10.2.1 Leaf Area Index and Succession -- 10.2.2 Power Output as a Function of Leaf Area Index -- 10.2.3 What Causes Changes in Leaf Area Index? -- 10.2.4 Maximum Entropy Production Principle -- 10.2.5 Successional Ecosystems Move Further from Thermodynamic Equilibrium -- 10.2.6 Entropy Storage by Animals -- 10.3 The Strategy of Ecosystem Development -- A Problem with Odum’s Strategy -- Why Power Output Continues to Increase -- Revised Definition of Maximum Power -- Costs of Ecosystem Stabilization -- Transactional Costs -- Succession, Power Output, and Efficiency -- 10.5.1 Kleiber’s Law -- Are Ecosystems Spendthrifts? -- Interactions Between Species Facilitate Increase in Power Output -- Facilitation -- Tolerance -- Inhibition -- Intermediate Disturbance Hypothesis -- Nutrient Use Efficiency during Succession -- Succession Following Logging vs Following Agriculture -- 10.10 Thermodynamic View of Succession: Implications for Resource Management -- References -- Panarchy -- The Universal Cycle of Systems -- Panarchy -- Thermodynamic Interpretation of the Sacred Rules -- 11.2.1 Growth and Consolidation -- 11.2.2 Collapse -- Renewal -- Sub-systems -- Panarchy over 2 Billion Years of Evolution -- Consolidation, Bureaucracy and System Collapse -- Bureaucracy in Action (Case Studies) -- Case Study: Panarchy in the Georgia Piedmont -- Thermodynamic Interpretation -- References -- 12. A Thermodynamic View of Evolution -- 12.1 Life – A Physicist's View -- 12.1.1 Life is Produced by Capturing Entropy -- 12.1.2 The Origin of Life -- 12.2 Two Approaches to Evolution -- 12.2.1 The Eco-Evo-Devo View -- 12.2.2 The Thermodynamic View -- 12.2.3 Fitness -- 12.2.4 The “Goal” of Evolution -- 12.3 The Relationship between Species and Environment -- 12.3.1 Evolution’s “Theater” -- 12.3.2 Is Evolution Stochastic or Deterministic? -- 12.4 Ecosystem Evolution -- 12.4.1 Succession was the Clue -- 12.4.2 Ecosystems Moved away from Equilibrium -- 12.4.3 Thermodynamic Mechanisms -- 12.4.4 Biological Mechanisms -- 12.4.5 Ecosystem Fitness -- 12.4.6 Ecosystems Evolve One Step at a Time -- 12.5. The Origin of Ecosystems -- 12.5.1 Origin of Feedback Loops -- 12.5.2 Origin of Trophic Levels -- 12.5.3 Why are there Trophic Levels? -- 12.6 The “Goal” of Ecosystem Evolution -- 12.6.1 Conflicting Goals? -- 12.6.2 “Motivations” of Species -- 12.6.3 The Earth Ecosystem -- 12.6.4 Why is there Resistance to the Idea of Ecosystem Evolution? -- 12.6.5 Evolution of Economic Systems -- 12.7 A Thermodynamic Model of Ecosystem Evolution -- 12.7.1 Network Models -- 12.7.2 Increase in Complexity of Trophic Webs -- 12.7.3 Evolution of Trophic Webs -- 12.7.4 Life Moves Ashore -- 12.8 Biodiversity and the Five Great Extinctions -- 12.8.1 The Cretaceous-Tertiary (K-T) Boundary Extinction -- 12.8.2The Amazing Sustainability of Trophic Chains -- 12.8.3 A Test of Thermodynamic Theory -- 12.9 Panarchy and Evolution -- 12.10 Thermodynamic Requirements for Living Systems on Other Planets -- References -- -- Why is Species Diversity Higher in the Tropics? -- 13.1 Tropical Explorations -- 13.2 A Few Theories -- 13.3 A Thermodynamic Explanation -- 13.3.1 The Latitudinal Energy Gradient -- 13.3.2 The Latitudinal Productivity Gradient -- 13.3.3 The Data -- 13.3.4 Other Factors Affecting Productivity -- 13.4 Empirical Evidence for a High Productivity High Diversity Correlation -- 13.5 Humboldt’s Enigma -- 13.5.1 Are Productivity and Species Richness Correlated on Tropical -- Mountains? -- 13.6 The Mechanism Linking Productivity and Diversity -- 13.7 Answer to “Why is Species Diversity Higher in the Tropics?” -- 13.7.1 Differences within the Tropics -- 13.8 Why is Species Diversity Low at High Latitudes? -- 13.9 An Economic Perspective on D.
    Abstract: Survival of the fittest” is a tautology, because those that are “fit” are the ones that survive, but to survive, a species must be “fit”. Modern evolutionary theory avoids the problem by defining fitness as reproductive success, but the complexity of life that we see today could not have evolved based on selection that favors only reproductive ability. There is nothing inherent in reproductive success alone that could result in higher forms of life. Evolution from a Thermodynamic Perspective presents a non-circular definition of fitness and a thermodynamic definition of evolution. Fitness means maximization of power output, necessary to survive in a competitive world. Evolution is the “storage of entropy”. “Entropy storage” means that solar energy, instead of dissipating as heat in the Earth, is stored in the structure of living organisms and ecosystems. Part one explains this in terms comprehensible to a scientific audience beyond biophysicists and ecosystem modelers. Part two applies thermodynamic theory in non-esoteric language to sustainability of agriculture, and to conservation of endangered species. While natural systems are stabilized by feedback, agricultural systems remain in a mode of perpetual growth, pressured by balance of trade and by a swelling population. The constraints imposed by thermodynamic laws are being increasingly felt as economic expansion destabilizes resource systems on which expansion depends.
    Type of Medium: Online Resource
    Pages: XXVI, 384 p. 1 illus. , online resource.
    Edition: 1st ed. 2022.
    ISBN: 9783030851866
    DDC: 577
    Language: English
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    Keywords: Ecology . ; Conservation biology. ; Applied ecology. ; Environmental management. ; Ecology. ; Conservation Biology. ; Applied Ecology. ; Environmental Management.
    Description / Table of Contents: Introduction: Taxonomy, distribution and conservation status of wild guanaco’s populations -- 1. Zooarchaeological and socio-anthropological perspective of the human - guanaco (Lama guanicoe) interaction over the last 6000 years in the Patagonia, Argentina -- 2. Interspecific competition between guanacos and livestock and its impact on Patagonian rangelands: review and synthesis -- 3. Health status of Patagonian guanaco and its relevance for conservation -- 4. Patagonian pumas and their ungulate prey in the 21st century, a key interaction in a degraded environment -- 5. International policies and national legislation concerning guanaco conservation, management and trade in Argentina -- 6. Guanaco sustainable management as a conservation strategy and socioeconomic rural development -- 7. Historical perspective and current advances in ecology, conservation and management of the guanaco in the Chilean Patagonia -- 8. Lessons for the future of conservation and sustainable use of guanacos.
    Abstract: This book relates one of the most representative species of Patagonian wildlife, the guanaco, to human societies across time, and explores how that relationship has changed over time due to different land uses and productive interests. The book provides information to understand these interactions, and contextualizes the current situation of this species. In some cases, it proposes possible solutions to conflicts, and also shows ongoing activities aimed at sustainable use and conservation. The audience for this book includes researchers, graduate students, policy makers and conservation and rural development professionals. In addition, it will serve as a tool for application authorities and field technicians on the use and conservation of wildlife, to define management actions for this species. .
    Type of Medium: Online Resource
    Pages: XII, 241 p. 23 illus., 16 illus. in color. , online resource.
    Edition: 1st ed. 2022.
    ISBN: 9783031066566
    Series Statement: Natural and Social Sciences of Patagonia,
    DDC: 577
    Language: English
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    Keywords: Ecology . ; Environment. ; Science Study and teaching. ; Environmental health. ; Sustainability. ; Environmental engineering. ; Biotechnology. ; Bioremediation. ; Ecology. ; Environmental Sciences. ; Science Education. ; Environmental Health. ; Sustainability. ; Environmental Engineering/Biotechnology.
    Description / Table of Contents: Part I: About Environmental Education -- Chapter 1 - Training and dissemination about the Environment: keys to impulse the abiotic component of Environmental Education -- Chapter 2 Educating to deliver environmentally focused social innovation -- Chapter 3 - Environmental education for sustainable development: working for fundamental rights -- Chapter 4 - Nature as a teaching resource and the nature of learning -- Part II: Environmental Education and it´s Teaching -- Chapter 5 - The importance of Nature-based solutions to enhance Cabo Verde's Environment -- Chapter 6- Development of Scientific Literacy and the impact of environmental attitudes of citizens in a geological natural space -- Chapter 7- A PBL approach to Environmental Education through a Field Trip and a Science Centre Visit -- Chapter 8- Living labs in higher education: sustainable buildings technologies -- Chapter 9 - What is doing Latin America regarding the teaching of Nature-based solutions to boost Environmental Education? -- Chapter 10 - Lessons learned from including aquaponic experiments into five different tertiary education curricula -- Chapter 11 - Recommendations for promoting Environmental Education through Nature-based solutions at Turkish Higher Education Institutes -- Part III: Environmental Education and Social Engagement -- Chapter 12 - Bees and Society: native biodiversity as a strategy for environmental education based on the processes of nature -- Chapter 13- Perceptions about Sustainable Development of visitants in an Environmental Education Natural Park -- Chapter 14 - Start Park project: co-designing green-blue infrastructures to build resilient communities to climate change -- Chapter 15 - Societal embedding in geoparks: a case study in Portugal -- Chapter 16 - Environmental Education in Naturtejo UNESCO Global Geopark (Portugal): a nature-based approach -- Part IV: – Environmental Education and Nature-Based Solutions -- Chapter 17- Green Roof and walls technology standardisation and market across Europe -- Chapter 18- How Nature-Based Solutions can Contribute to Enhance Circularity in Cities -- Chapter 19- Nature-based solutions to promote environmental education on integral ecological sanitation -- Chapter 20 - Nature-based solutions for environmental education in the East Asian context -- Chapter 21- Decarbonizing the European energy sector: frameworks, examples and how education plays a key role -- Chapter 22- Nature-based solutions for water pollution control: promoting environmental education through case studies.
    Abstract: This Book presents innovative and state of the art studies developed in Environmental Education in different countries to highlight this theme and promote its implementation all over the world. It will give a scientific perspective of Nature-based solutions to promote environmental education in all citizens and a more educational perspective as to how this approach can be implemented at schools and universities. Not less important is that includes science communication as a key factor for training and disseminating about the environment. The invited authors are recognized experts with excellent work developed in Environmental Education. This contributed volume presents innovative and creative work in the area giving a step forward in the implementation of Environmental Education, namely as a target of 2020 United Nations Agenda for Sustainable Development. The invitation of authors from many different countries allows the creation of a network and subsequently the book will bring concrete ideas as to how to develop operational capacities to bring added values to Environmental Education at an international level.
    Type of Medium: Online Resource
    Pages: XI, 432 p. 117 illus., 89 illus. in color. , online resource.
    Edition: 1st ed. 2022.
    ISBN: 9783030918439
    Series Statement: Integrated Science, 4
    DDC: 577
    Language: English
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    Online Resource
    Online Resource
    Cham :Springer International Publishing :
    Keywords: Immunology. ; Immune system. ; Cellular signal transduction. ; Cytology. ; Autoimmunity. ; Immunospecificity. ; Immunology. ; Immune Cell Signalling. ; Cell Biology. ; Autoimmunity. ; Adaptive Immunity.
    Description / Table of Contents: Class I PI3K biology -- Class II PI3K biology -- Class III PI3K biology -- PTEN in immunity -- PHLPP Signaling in Immune Cells -- PHLPP Signaling in Immune Cells -- PI3K isoforms in cell signalling and innate immune cell responses -- AKT isoforms in macrophage activation, polarization and survival -- Control of CD4+ T cell Differentiation and Function by PI3K isoforms. -- PI3K isoforms in CD8+ T cell development and function -- PI3K isoforms in B cells -- PI3K isoform signalling in platelets -- PI3K isoforms in vascular biology, a focus on the vascular system-immune response connection -- PI3K and AKT at the Interface of Signaling and Metabolism -- The Role of PI3K Isoforms in Autoimmune Disease -- AKT Isoforms in the Immune Response in Cancer -- PI3K isoform immunotherapy for solid tumours -- PI3K targeting in non-solid cancer -- AKT isoforms as a target in cancer and immunotherapy -- Developing PI3K Inhibitors for Respiratory Diseases.
    Abstract: This book provides an essential overview of the role of phosphoinositide-3-phosphate kinase (PI3K) isoforms in modulating the function of immune system cells and their involvement in disease. PI3K is a family of kinases involved in basic cellular processes such as proliferation, migration and cell death. Recent work has highlighted the multiple roles of PI3K classes and subunits and their involvement in the immune response to the body’s own and foreign antigens and diseases such as cancer and autoimmunity. This book offers a detailed introduction to the biology of the three PI3K classes, followed by an extensive discussion of the diverse roles of AKT and PI3K isoforms in immune cells. Based on this knowledge, it subsequently explains in more detail how specific isoforms are connected to immune-mediated diseases. The book concludes by highlighting the latest advances in the production of isoform-specific inhibitors and their use in various human diseases. This book is intended as a reference guide for students and researchers interested in the multifaceted aspects of PI3K biology.
    Type of Medium: Online Resource
    Pages: VII, 466 p. 42 illus., 37 illus. in color. , online resource.
    Edition: 1st ed. 2022.
    ISBN: 9783031065668
    Series Statement: Current Topics in Microbiology and Immunology, 436
    DDC: 571.96
    Language: English
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    Online Resource
    Online Resource
    Cham :Springer International Publishing :
    Keywords: Ecology . ; Botany. ; Physical geography. ; Conservation biology. ; Ecology. ; Plant Science. ; Earth System Sciences. ; Conservation Biology.
    Description / Table of Contents: PRELIMINARY (ToC of second edition) 1 Plant ecology at high elevations -- The concept of limitation -- A regional and historical account -- The challenge of alpine plant research -- 2 The alpine life zone -- Altitudinal boundaries -- Global alpine land area -- Alpine plant diversity -- Origin of alpine floras -- Alpine growth forms -- 3 Alpine climate -- Which alpine climate -- Common features of alpine climates -- Regional features of alpine climates -- 4 The climate plants experience -- Interactions of relief, wind and sun -- How alpine plants influence their climate -- The geographic variation of alpine climate -- 5 Life under snow: protection and limitation -- Temperatures under snow -- Solar radiation under snow -- Gas concentrations under snow -- Plant responses to snowpack -- 6 Alpine soils -- Physics of alpine soil formation -- The organic compound -- The interaction of organic and inorganic compounds -- 7 Alpine treelines -- About trees and lines -- Current altitudinal positions of climatic treelines -- Treeline-climate relationships -- Intrazonal variations and pantropical plateauing of alpine treelines -- Treelines in the past -- Attempts at a functional explanation of treelines -- A hypothesis for treeline formation -- Growth trends near treelines -- Evidence for sink limitation -- 8 Climatic stress -- Survival of low temperature extremes -- Avoidance and tolerance of low temperature extremes -- Heat stress in alpine plants -- Ultraviolet radiation — a stress factor -- 9 Water relations -- Ecosystem water balance -- Soil moisture at high altitudes -- Plant water relations — a brief review of principles -- Water relations of alpine plants -- Desiccation stress -- Water relations of special plant types -- 10 Mineral nutrition -- Soil nutrients -- The nutrient status of alpine plants -- Nutrient cycling and nutrient budgets -- Nitrogen fixation -- Mycorrhiza -- Responses of vegetation to variable nutrient supply -- 11 Uptake and loss of carbon -- Photosynthetic capacity of alpine plants -- Photosynthetic responses to the environment -- Daily carbon gain of leaves -- The seasonal carbon gain of leaves -- C4 and CAM photosynthesis at high altitudes -- Tissue respiration of alpine plants -- Ecosystem carbon balance -- 12 Carbon investments -- Non-structural carbohydrates -- Lipids and energy content -- Carbon costs of leaves and roots -- Whole plant carbon allocation -- 13 Growth dynamics and phenology -- Seasonal growth -- Diurnal leaf extension -- Rates of plant dry matter accumulation -- Functional duration of leaves and roots -- 14 Cell division and tissue formation -- Cell size and plant size -- Mitosis and the cell cycle -- From meristem activity to growth control -- 15 Plant biomass production -- The structure of alpine plant canopies -- Primary productivity of alpine vegetation -- Plant dry matter pools -- Biomass losses through herbivores -- 16 Plant reproduction -- Flowering and pollination -- Seed development and seed size -- Germination -- Alpine seed banks and natural recruitment -- Clonal propagation -- Alpine plant age -- Community processes -- 17 Global change at high elevation -- Alpine land use -- The impact of altered atmospheric chemistry -- Climatic change and alpine ecosystems -- References (with chapter annotation) -- Taxonomic index (genera) -- Geographical index -- Color plates -- Plant life forms -- The alpine life zone -- Environmental stress -- The human dimension.
    Abstract: This book is a completely revised, substantially extended treatment of the physical and biological factors that drive life in high mountains. The book covers the characteristics of alpine plant life, alpine climate and soils, life under snow, stress tolerance, treeline ecology, plant water, carbon, and nutrient relations, plant growth and productivity, developmental processes, and two largely novel chapters on alpine plant reproduction and global change biology. The book explains why the topography driven exposure of plants to dramatic micro-climatic gradients over very short distances causes alpine biodiversity to be particularly robust against climatic change. Geographically, this book draws on examples from all parts of the world, including the tropics. This book is complemented with novel evidence and insight that emerged over the last 17 years of alpine plant research. The number of figures – mostly in color – nearly doubled, with many photographs providing a vivid impression of alpine plant life worldwide. Christian Körner was born in 1949 in Austria, received his academic education at the University of Innsbruck, and was full professor of Botany at the University of Basel from 1989 to 2014. As emeritus Professor he is continuing alpine plant research in the Swiss Alps.
    Type of Medium: Online Resource
    Pages: XIX, 500 p. 319 illus., 283 illus. in color. , online resource.
    Edition: 3rd ed. 2021.
    ISBN: 9783030595388
    DDC: 577
    Language: English
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    Keywords: Ecology . ; Botany. ; Zoology. ; Conservation biology. ; Ecology. ; Plant Science. ; Zoology. ; Conservation Biology.
    Description / Table of Contents: Part 1: Historical and biogeographical aspects -- The Atlantic Forest: an introduction to the megadiverse forest of Southern America -- The Atlantic Forest Ecological History: from pre-history to the Anthropocene -- The North-eastern Atlantic Forest: biogeographical, historical and current aspects in the Sugarcane Zone -- The Hileia Baiana - an assessment of natural and historical aspects of the land use and degradation of the central corridor of the Brazilian Atlantic Forest -- The southern Atlantic Forest: Use, degradation, and perspectives for conservation -- Part II – Biodiversity -- Tree diversity in the Brazilian Atlantic Forest: biases and general patterns using different sources of information -- Vascular Epiphytes of the Atlantic Forest: diversity and community ecology -- Social Insects of the Atlantic Forest -- Tetrapod diversity in the Atlantic Forest: maps and gaps -- Freshwater Studies in Atlantic Forest: general overview and prospects -- Part III – Threats -- Land-cover changes and an uncertain future: will the Brazilian Atlantic Forest lose the chance to become a hopespot? -- Climate change and biodiversity in the Atlantic Forest: best climatic models, predicted changes and impacts, and adaptation options -- Non-native species introductions, invasions, and biotic homogenization in the Atlantic Forest -- Causes and consequences of large-scale defaunation in the Atlantic forest -- Pollination systems in the Atlantic Forest: characterization, threats, and opportunities -- IV - Opportunities -- Atlantic Forest: ecosystem services linking people and biodiversity -- Changing the agriculture paradigm in the Brazilian Atlantic Forest: the importance of agroforestry -- Engaging people for large-scale forest restoration: Governance lessons from the Atlantic Forest of Brazil -- The Atlantic Forest Trail: connecting people, biodiversity and protected areas -- Conservation initiatives in the Brazilian Atlantic forest -- Financing conservation in the Brazilian Atlantic Forest -- Integrating researchers for understanding the biodiversity in Atlantic Forest -- The future of the Atlantic Forest.
    Abstract: The Atlantic Forest is one of the 36 hotspots for biodiversity conservation worldwide. It is a unique, large biome (more than 3000 km in latitude; 2500 in longitude), marked by high biodiversity, high degree of endemic species and, at the same time, extremely threatened. Approximately 70% of the Brazilian population lives in the area of this biome, which makes the conflict between biodiversity conservation and the sustainability of the human population a relevant issue. This book aims to cover: 1) the historical characterization and geographic variation of the biome; 2) the distribution of the diversity of some relevant taxa; 3) the main threats to biodiversity, and 4) possible opportunities to ensure the biodiversity conservation, and the economic and social sustainability. Also, it is hoped that this book can be useful for those involved in the development of public policies aimed at the conservation of this important global biome.
    Type of Medium: Online Resource
    Pages: XXX, 517 p. 66 illus., 44 illus. in color. , online resource.
    Edition: 1st ed. 2021.
    ISBN: 9783030553227
    DDC: 577
    Language: English
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    Online Resource
    Online Resource
    Cham :Springer International Publishing :
    Keywords: Immunology. ; Rheumatology. ; Diseases. ; Hematology. ; Oncology. ; Primary care (Medicine). ; Immunology. ; Rheumatology. ; Diseases. ; Hematology. ; Oncology. ; Primary Care Medicine.
    Description / Table of Contents: Chapter 1. Overview of Immunodeficiency -- Part I. B-Lymphocyte Immunodeficiency -- Chapter 2. Common Variable Immunodeficiency, Hypogammaglobulinemia, and Specific Antibody Deficiency -- Chapter 3. Agammaglobulinemia -- Chapter 4. Class Switch Defects -- Chapter 5. Transient Immunodeficiency of Infancy -- Chapter 6. Selective Isotype Immunodeficiency -- Chapter 7. Common Variable Immunodeficiency Disorders-like Disorders -- Part II. T-Cell Immunodeficiency -- Chapter 8. Severe Combined Immunodeficiency -- Chapter 9. Idiopathic CD4 Lymphopenia -- Chapter 10. Hyper IgE Syndrome -- Chapter 11. Genetic Syndromes with Associated Immunodeficiencies -- Part III. Immune Dysregulation Syndromes -- Chapter 12. Autoimmune Lymphoproliferative Syndrome -- Chapter 13. Auto-inflammatory Syndromes -- Chapter 14. Immune Dysregulation Leading to Autoimmunity -- Chapter 15. Dendritic Cells in Primary Immunodeficiency -- Part IV. Innate Immune Defects -- Chapter 16. Congenital Neutropenia and Migration Defects -- Chapter 17. Chronic Granulomatous Disease -- Chapter 18. Primary Immunodeficiencies of Complement -- Chapter 19. Natural Killer Cell Defects -- Chapter 20. Mucocutaneous Candidiasis -- Part V. Secondary Immunodeficiency -- Chapter 21. Immunodeficiency Secondary to Malignancies and Biologics -- Chapter 22. Immunodeficiency Secondary to Prematurity, Pregnancy, and Aging -- Chapter 23. Vaccinations in Primary and Secondary Immunodeficiencies Including Asplenia.
    Abstract: This book provides a broad clinical overview of primary and secondary immunodeficiencies nested in clinical cases that will help the reader understand the approach to evaluation, diagnosis, and management of these challenging cases. Chapters begin with a comprehensive overview of immunodeficiencies to ground the reader in practical knowledge of the field and these complex conditions. Chapters cover B lymphocyte immunodeficiency, T cell immunodeficiency, immune dysregulation syndromes, and innate immune defects. They discuss a range of treatment options including gene therapy or bone marrow transplant. The book continues with a discussion on secondary immunodeficiencies and their treatment. Each chapter was written by authors with expertise related to different immunodeficiency disorders and provide a succinct overview of pathomechanisms, diagnosis, and treatment of a specific condition. Primary and Secondary Immunodeficiency will be an excellent resource for practicing allergists, hematologists, clinical immunologists, fellows, residents, and other clinicians who work with immunodeficiency patients.
    Type of Medium: Online Resource
    Pages: XI, 417 p. 34 illus., 22 illus. in color. , online resource.
    Edition: 1st ed. 2021.
    ISBN: 9783030571573
    DDC: 571.96
    Language: English
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    Keywords: Biotic communities. ; Environment. ; Ecology . ; Landscape ecology. ; Ecosystems. ; Environmental Sciences. ; Terrestial Ecology. ; Landscape Ecology. ; Ecology.
    Description / Table of Contents: Chapter 1. Introduction (Deborah C. Hayes, Becky K. Kerns, Toral Patel-Weynand, and Deborah M. Finch) -- Chapter 2. Impacts of Invasive Species in Terrestrial and Aquatic Systems in the United States (Albert E. Mayfield III, Steven J. Seybold, Wendell R. Haag, M. Tracy Johnson, Becky K. Kerns, John C. Kilgo, Daniel J. Larkin, Rima D. Lucardi, Bruce D. Moltzan, Dean E. Pearson, John D. Rothlisberger, Jeffrey D. Schardt, Michael K. Schwartz, and Michael K. Young) -- Chapter 3. Impacts of Invasive Species on Forest and Grassland Ecosystem Processes in the United States (Chelcy Ford Miniat, Jennifer M. Fraterrigo, Steven T. Brantley, Mac A. Callaham, Jr., Susan Cordell, Jeffrey S. Dukes, Christian P. Giardina, Shibu Jose, and Gary Lovett) -- Chapter 4. Effects of Climate Change on Invasive Species (Deborah M. Finch, Jack L. Butler, Justin B. Runyon, Christopher J. Fettig, Francis F. Kilkenny, Shibu Jose, Susan J. Frankel, Samuel A. Cushman, Richard C. Cobb, Jeffrey S. Dukes, Jeffrey A. Hicke, and Sybill K. Amelon) -- Chapter 5. Invasive Species Response to Natural and Anthropogenic Disturbance (Susan E. Meyer, Mac A. Callaham, Jr., Jane E. Stewart, and Steven D. Warren) -- Chapter 6. Early Intervention Strategies for Invasive Species Management: Connections Between Risk Assessment, Prevention Efforts, Eradication, and Other Rapid Responses (Robert C. Venette, Doria R. Gordon, Jennifer Juzwik, Frank H. Koch, Andrew M. Liebhold, Robert K.D. Peterson, Sharlene E. Sing, and Denys Yemshanov) -- Chapter 7. Management of Landscapes for Established Invasive Species (Therese M. Poland, Jennifer Juzwik, Allen Rowley, Cynthia D. Huebner, John C. Kilgo, Vanessa M. Lopez, Deanna H. Olson, Dean Pearson, Robert Progar, Robert Rabaglia, John D. Rothlisberger, Justin B. Runyon, and Sharlene E. Sing) -- Chapter 8. Restoration of Landscapes and Habitats Affected by Established Invasive Species (Jennifer Koch, Dean E. Pearson, Cynthia D. Huebner, Michael K. Young, and Richard A. Sniezko) -- Chapter 9. Sectoral Impacts of Invasive Species in the United States and Approaches to Management (Anne S. Marsh, Deborah C. Hayes, Patrice N. Klein, Nicole Zimmerman, Alison Dalsimer, Douglas A. Burkett, Cynthia D. Huebner, Robert Rabaglia, Laura A. Meyerson, Bonnie L. Harper-Lore, Jamie L. Davidson, Marla R. Emery, Travis Warziniack, Rebecca Flitcroft, Becky K. Kerns, and Vanessa M. Lopez) -- Chapter 10. Inventory and Monitoring of Invasive Species (Sonja Oswalt, Chris Oswalt, Alycia Crall, Robert Rabaglia, Michael Schwartz, and Becky K. Kerns) -- Chapter 11. Tools and Technologies for Quantifying Spread and Impacts of Invasive Species (Matt Reeves, Inés Ibáñez, Dana Blumenthal, Gang Chen, Qinfeng Guo, Catherine Jarnevich, Jennifer Koch, Frank Sapio, Michael K. Schwartz, Bruce K. Wylie, and Stephen Boyte) -- Chapter 12. Social and Cultural Dynamics of Non-Native Invasive Species (John Schelhas, Janice Alexander, Mark Brunson, Tommy Cabe, Alycia Crall, Michael J. Dockry, Marla R. Emery, Susan J. Frankel, Nina Hapner, Caleb R. Hickman, Rebecca Jordan, Michael J. LaVoie, Zhao Ma, Ross K. Meentemeyer, Joe Starinchak, and Jelena Vukomanovic) -- Chapter 13. The Role of International Cooperation in Invasive Species Research (Andrew Liebhold, Faith Campbell, Doria R. Gordon, Qinfeng Guo, Nathan Havill, Bradley Kinder, Richard MacKenzie, David R. Lance, Dean Pearson, Sharlene E. Sing, Travis Warziniack, Robert C. Venette, and Denys Yemshanov) -- Chapter 14. Economics of Invasive Species (Travis Warziniack, Robert G. Haight, Denys Yemshanov, Jenny L. Apriesnig, Thomas P. Holmes, Amanda M. Countryman, John D. Rothlisberger, and Christopher Haberland) -- Chapter 15. Legislation and Policy (Faith T. Campbell, Hilda Diaz-Soltero, and Deborah C. Hayes) -- Chapter 16. Future Invasive Species Research Challenges and Opportunities (Becky K. Kerns, Therese M. Poland, Robert C. Venette, Toral Patel-Weynand, Deborah M. Finch, Allen Rowley, Deborah C. Hayes, Mike Ielmini) -- APPENDIX 1: Regional Summaries.
    Abstract: This open access book describes the serious threat of invasive species to native ecosystems. Invasive species have caused and will continue to cause enormous ecological and economic damage with ever increasing world trade. This multi-disciplinary book, written by over 100 national experts, presents the latest research on a wide range of natural science and social science fields that explore the ecology, impacts, and practical tools for management of invasive species. It covers species of all taxonomic groups from insects and pathogens, to plants, vertebrates, and aquatic organisms that impact a diversity of habitats in forests, rangelands and grasslands of the United States. It is well-illustrated, provides summaries of the most important invasive species and issues impacting all regions of the country, and includes a comprehensive primary reference list for each topic. This scientific synthesis provides the cultural, economic, scientific and social context for addressing environmental challenges posed by invasive species and will be a valuable resource for scholars, policy makers, natural resource managers and practitioners.
    Type of Medium: Online Resource
    Pages: XLII, 455 p. 87 illus., 67 illus. in color. , online resource.
    Edition: 1st ed. 2021.
    ISBN: 9783030453671
    DDC: 577
    Language: English
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    Keywords: Biotic communities. ; Environmental monitoring. ; Environmental management. ; Environmental chemistry. ; Pollution. ; Ecosystems. ; Environmental Monitoring. ; Environmental Management. ; Environmental Chemistry. ; Pollution.
    Description / Table of Contents: Part I. Soil and Sediment Contaminants, Risk Assessment and Remediation -- Chapter 1. Introduction to Part I: Soil and Sediment Contaminants, Risk Assessment and Remediation -- Chapter 2. Combating Arsenic Pollution in Soil Environment via Alternate Agricultural Land Use -- Chapter 3. Temporal and Seasonal Variation in Leachate Pollution Index (LPI) in Sanitary Landfill Sites- A Case study of Baidyabati landfill, West Bengal, India -- Chapter 4.Quantification of Landfill Gas Emission and Energy Recovery Potential: A Comparative Assessment of LandGEM and MTM Model for Kolkata -- Chapter 5. Assessment of natural enrichment of heavy minerals along coastal placers of India: Role of lake and river mouth embayment and its implications -- Chapter 6. Assessment the Impact of Plastic Contaminated Fertilizers on Agricultural Soil Health: A Case Study in Memari II C.D.Block, Purba Bardhaman,West Bengal, India -- Chapter 7. Determining the Role of Leaf Relative Water Content and Soil Cation Exchange Capacity in Phytoextraction Process – Using Regression Modelling -- Chapter 8. Phytoremediation of Arsenic using Allium sativum as Model System -- Chapter 9. Spatio-temporal analysis of open waste dumping sites using Google Earth: A case study of Kharagpur City, India -- Part II. Water Contaminants, Risk Assessment and Remediation -- Chapter 10. Introduction to Part II: Water Contaminants, Risk Assessment and Remediation -- Chapter 11. Groundwater Arsenic Contamination Zone based on geospatial modeling, risk and remediation -- Chapter 12. Geospatial assessment of surface water pollution and industrial activities in Ibadan, Nigeria -- Chapter 13. Aquaculture-based water quality assessment and risk remediationalong the Rasulpur River belt, West Bengal -- Chapter 14. Heavy Metal Contamination in Groundwater and Impact on Plant and Human -- Chapter 15. Emerging Threats of Microplastic contaminant in freshwater environment -- Chapter 16. Exploring Particle Size Transport Variability of Suspended Sediments in two Alpine Catchments over the Lesser Himalayan Region, India -- Chapter 17. Salinity and corrosion potential of groundwater in Mewat district of Haryana, India -- Chapter 18. Threats to quality in the coasts of the Black Sea: heavy metal pollution of seawater, sediment, macro-algae and sea-grass -- Chapter 19. Geospatial assessment of groundwater quality for drinking through Water Quality Index and Human Health Risk Index in an upland area of Chotanagpur Plateau of West Bengal, India -- Chapter 20. Existence of Pharmaceuticals and Personal Care Products (PPCPs) in the conventional water treatment process -- Chapter 21. Arsenic-rich surface and groundwater around eastern parts of Rupnagar district, Punjab, India -- Part III. Environmental Contaminants, Impacts and Sustainable Management -- Chapter 22. Introduction to Part III: Environmental Contaminants, Risk Assessment and Remediation -- Chapter 23. Dynamics of ultra-fine particles in indoor and outdoor environments: a modelling approach to study the evolution of particle characteristics -- Chapter 24. Environmental impacts of coal-mining and coal-fired power-plant activities in a developing country with global context -- Chapter 25. Overview of Indoor air pollution: A human health perspective -- Chapter 26. Mineralogy and Morphological characterization of Technogenic Magnetic Particles (TMP) from industrial dust: Insights into environmental implications -- Chapter 27. Pesticides: Recent Updates on Types Toxicity and Bioremediation Strategies -- Chapter 28. Commonly available plant neem (Azadirachtaindica A. Juss) ameliorates dimethoate induced toxicity in climbing perch Anabas testudineus -- Chapter 29. Estimating Particulate Matter concentrations from MODIS AOD considering meteorological parameters using Random Forest Algorithm -- Chapter 30 Bio-monitoring and bioremediation of a trans-boundary river in India: Functional roles of benthic mollusks and fungi -- Chapter 31 Assessing the Maximum Aerobic Biodegradation Potential of Leaf Litter, an Organic Fraction of Municipal Solid Waste, Under Optimum Nutrient Conditions -- Chapter 32. Rising trend of air pollution and its decadal consequences on meteorology and thermal comfort over Gangetic West Bengal, India.
    Abstract: This book demonstrates the measurement, monitoring and mapping of environmental contaminants in soil & sediment, surface & groundwater and atmosphere. This book explores state-of-art techniques based on methodological and modeling in modern geospatial techniques specifically focusing on the recent trends in data mining techniques and robust modeling. It also presents modifications of and improvements to existing control technologies for remediation of environmental contaminants. In addition, it includes three separate sections on contaminants, risk assessment and remediation of different existing and emerging pollutants. It covers major topics such as: Radioactive Wastes, Solid and Hazardous Wastes, Heavy Metal Contaminants, Arsenic Contaminants, Microplastic Pollution, Microbiology of Soil and Sediments, Soil Salinity and Sodicity, Aquatic Ecotoxicity Assessment, Fluoride Contamination, Hydrochemistry, Geochemistry, Indoor Pollution and Human Health aspects. The content of this book will be of interest to researchers, professionals, and policymakers whose work involves environmental contaminants and related solutions.
    Type of Medium: Online Resource
    Pages: XX, 720 p. 225 illus., 185 illus. in color. , online resource.
    Edition: 1st ed. 2021.
    ISBN: 9783030634223
    Series Statement: Environmental Challenges and Solutions,
    DDC: 577
    Language: English
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    Online Resource
    Online Resource
    Cham :Springer International Publishing :
    Keywords: Immunology. ; Human physiology. ; Medicine Research. ; Biology Research. ; Respiratory organs Diseases. ; Immunology. ; Human Physiology. ; Biomedical Research. ; Pneumology.
    Description / Table of Contents: 1. Can GPCRs be targeted to control inflammation in asthma? -- 2. Cellular and molecular processes in pulmonary hypertension -- 3. INFLAMMATORY PATHWAYS IN SARCOIDOSIS -- 4. Innate Immune Responses and Pulmonary Diseases -- 5. Interstitial Lung Disease associated with Connective Tissue Diseases -- 6. Molecular mechanisms of vascular damage during lung injury -- 7. Neurotrophin Regulation and Signaling in Airway Smooth Muscle -- 8. Novel Thoracic MRI approaches for the assessment of pulmonary physiology and inflammation -- 9. Overview on Interactive Role of Inflammation, Reactive Oxygen Species and Calcium signaling in Asthma, COPD and Pulmonary Hypertension -- 10. Protein S-palmitoylation and lung diseases -- 11. Redox role of ROS and inflammation in pulmonary diseases -- 12. Semaphorin3E/PlexinD1 axis in asthma: what we know so far -- 13. Serine protease inhibitors to treat lung inflammatory diseases -- 14. Sex and Gender Differences in Lung Disease -- 15. Sex hormones and lung inflammation -- 16. Synopsis of Clinical Acute Respiratory Distress Syndrome (ARDS).
    Abstract: Lung diseases are leading causes of death and disability globally, with about 65 million people suffering from COPD, and 334 million from asthma. Each year, tens of millions of people develop and can die from lung infections such as pneumonia and TB. Systemic inflammation may induce and exacerbate local inflammatory diseases in the lungs, and local inflammation can in turn cause systemic inflammation. There is increasing evidence of the coexistence of systemic and local inflammation in patients suffering from asthma, COPD, and other lung diseases, and the co-morbidity of two or more local inflammatory diseases often occurs. For example, rheumatoid arthritis frequently occurs together with, and promotes the development of, pulmonary hypertension. This co-morbidity significantly impacts quality of life, and can result in death for some patients. Current treatment options for lung disease are neither always effective, nor condition-specific; there is a desperate need for novel therapeutics in the field. Additionally, the molecular and physiological significance of most major lung diseases is not well understood, which further impedes development of new treatments, especially in the case of coexistent lung diseases with other inflammatory diseases. Great progress has been made in recent years in many areas of the field, particularly in understanding the molecular geneses, regulatory mechanisms, signalling pathways, and cellular processes within lung disease, as well as basic and clinical technology, drug discovery, diagnoses, treatment options, and predictive prognoses. This is the first text to aggregate these developments. In two comprehensive volumes, experts from all over the world present state-of-the-art advances in the study of lung inflammation in health and disease. Contributing authors cover well-known as well as emerging topics in basic, translational, and clinical research, with the aim of providing researchers, clinicians, professionals, and students with new perspectives and concepts. The editors hope these books will also help to direct future research in lung disease and other inflammatory diseases, and result in the development of novel therapeutics.
    Type of Medium: Online Resource
    Pages: XVI, 384 p. 42 illus., 29 illus. in color. , online resource.
    Edition: 1st ed. 2021.
    ISBN: 9783030687489
    Series Statement: Advances in Experimental Medicine and Biology, 1304
    DDC: 571.96
    Language: English
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    Keywords: Biotic communities. ; Forestry. ; Physical geography. ; Applied ecology. ; Ecology . ; Ecosystems. ; Forestry. ; Earth System Sciences. ; Applied Ecology. ; Terrestial Ecology.
    Description / Table of Contents: Chapter 1. Introduction to Fire Ecology across USA Forested Ecosystems: Past, Present, and Future (Cathryn H. Greenberg, Beverly S. Collins, Scott Goodrick, Michael C. Stambaugh, and Gary R. Wein) -- Chapter 2. The Role of Fire in the Dynamics of Piedmont Vegetation (Joanna Spooner, Robert K. Peet, Michael P. Schafale, Alan S. Weakley and Thomas R. Wentworth) -- Chapter 3. Fire Ecology and Fire Management of Southeastern Coastal Plain Pine Ecosystems (Jeff S. Glitzenstein, J. Stephen Brewer, Ronald. E. Masters, J. Morgan Varner, and J. Kevin Hiers) -- Chapter 4. Fire Ecology and Management in Eastern Broadleaf and Appalachian Forests (Mary A. Arthur, J. Morgan Varner, Charles W. Lafon, Heather D. Alexander, Daniel C. Dey, Craig A. Harper, Sally P. Horn, Todd F. Hutchinson, Tara L. Keyser, Marcus A. Lashley, Christopher E. Moorman, and Callie J. Schweitzer) -- Chapter 5. Fire Ecology and Management of Forest Ecosystems in the Western Central Hardwoods and Prairie-Forest Border (Michael C. Stambaugh, Benjamin O. Knapp, and Daniel C. Dey) -- Chapter 6. Fire in Floodplain Forests of the Southeastern USA hy (Paul R. Gagnon, Loretta L. Battaglia, Brice B. Hanberry, William H. Conner, and Sammy L. King) -- Chapter 7. History and Future of Fire in Hardwood and Conifer Forests of the Great Lakes-Northeastern Forest Region, USA(Lee E. Frelich, Craig G. Lorimer, and Michael C. Stambaugh) -- Chapter 8. Fire Ecology of Rocky Mountain Forests(Sharon M. Hood, Brian J. Harvey, Paula J. Fornwalt, Cameron E. Naficy, Winslow D. Hansen, Kimberley T. Davis, Mike A. Battaglia, Camille Stevens-Rumann, Victoria Saab) -- Chapter 9. Fire Ecology of the North American Mediterranean-Climate Zone(Hugh D. Safford, Ramona J. Butz, Gabrielle N. Bohlman, Michelle Coppoletta, Becky L. Estes, Shana E. Gross, Kyle E. Merriam, Marc D. Meyer, Nicole A. Molinari, and Amarina Wuenschel) -- Chapter 10. Fire Ecology and Management in Pacific Northwest Forests(Matthew J. Reilly, Jessica E. Halofsky, Meg A. Krawchuk, Daniel C. Donato, Paul F. Hessburg, James Johnston, Andrew Merschel, Mark E. Swanson, Joshua S. Halofsky, and Thomas A. Spies) -- Chapter 11. Fire Ecology and Management of Southwestern Forests(Peter Z. Fulé, Catrin M. Edgeley, Carol L. Chambers, Serra Hoagland, Blanca Céspedes) -- Chapter 12. Fire and Forests in the 21st Century: Managing Resilience under Changing Climates and Fire Regimes in USA Forests(James M. Vose, David L. Peterson, Christopher J. Fettig, Jessica E. Halofsky, J. Kevin Hiers, Robert E. Keane, Rachel Loehman, and Michael C. Stambaugh).
    Abstract: This edited volume presents original scientific research and knowledge synthesis covering the past, present, and potential future fire ecology of major US forest types, with implications for forest management in a changing climate. The editors and authors highlight broad patterns among ecoregions and forest types, as well as detailed information for individual ecoregions, for fire frequencies and severities, fire effects on tree mortality and regeneration, and levels of fire-dependency by plant and animal communities. The foreword addresses emerging ecological and fire management challenges for forests, in relation to sustainable development goals as highlighted in recent government reports. An introductory chapter highlights patterns of variation in frequencies, severities, scales, and spatial patterns of fire across ecoregions and among forested ecosystems across the US in relation to climate, fuels, topography and soils, ignition sources (lightning or anthropogenic), and vegetation. Separate chapters by respected experts delve into the fire ecology of major forest types within US ecoregions, with a focus on the level of plant and animal fire-dependency, and the role of fire in maintaining forest composition and structure. The regional chapters also include discussion of historic natural (lightning-ignited) and anthropogenic (Native American; settlers) fire regimes, current fire regimes as influenced by recent decades of fire suppression and land use history, and fire management in relation to ecosystem integrity and restoration, wildfire threat, and climate change. The summary chapter combines the major points of each chapter, in a synthesis of US-wide fire ecology and forest management into the future. This book provides current, organized, readily accessible information for the conservation community, land managers, scientists, students and educators, and others interested in how fire behaviour and effects on structure and composition differ among ecoregions and forest types, and what that means for forest management today and in the future. .
    Type of Medium: Online Resource
    Pages: XVII, 502 p. 71 illus., 65 illus. in color. , online resource.
    Edition: 1st ed. 2021.
    ISBN: 9783030732677
    Series Statement: Managing Forest Ecosystems, 39
    DDC: 577
    Language: English
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    Keywords: Immunology. ; Neurosciences. ; Virology. ; Immunology. ; Neuroscience. ; Virology.
    Description / Table of Contents: I. Neuropathogenesis and Biomarkers -- New Potential Axes of HIV Neuropathogenesis with Relevance to Biomarkers and Treatment -- Neurocognitive Impairment and Associated Genetic Aspects in HIV Infection -- Inflammatory Mechanisms and Cascades Contributing to Neurocognitive Impairment in HIV/AIDS -- Neuroimaging Advances in Diagnosis and Differentiation of HIV, Comorbidities, and Aging in the cART Era -- II. Neurocognitive Impairments in Low-, Middle- and High-Income Countries – Incidence / Prevalence and Contexts -- Neurocognitive Complications of Pediatric HIV Infections -- Neurocognitive Complications of HIV Infection in Women: Insights from the WIHS Cohort -- Cultural Neuropsychology Considerations in the Diagnosis of HIV- Associated Neurocognitive Disorders -- Neurocognitive Complications of HIV Infection in Low-Income Countries -- Deep Phenotyping of HIV Neurocognitive Complications Among Individuals Residing in High-Income Countries -- Reliably Measuring Cognitive Change in the Era of Chronic HIV Infection and Chronic HIV-Associated Neurocognitive Disorders -- III. Comorbidities and Complications -- Geriatric Syndromes in People Living with HIV Associated with Ageing and Increasing Comorbidities: Implications for Neurocognitive Complications of HIV Infection -- Conceptualizing and Assessing Everyday Functioning in the Context of HIV-Associated Neurocognitive Disorders -- Neuropsychiatric Disorders, Emotional Disturbances, and Their Associations with HIV-Associated Neurocognitive Disorder -- Metabolic Syndrome and Cardiovascular Disease Impacts on the Pathophysiology and Phenotype of HIV-Associated Neurocognitive Disorders -- HIV-Associated Neurocognitive Disorder (HAND): Relative Risk Factors -- IV. Screening, Interventions and Clinical Management -- Screening for HIV-Associated Neurocognitive Disorders: Sensitivity and Specificity -- Behavioral and Physical Activity Interventions for HAND -- Targeting HIV-Related Neurocognitive Impairments with Cognitive Training Strategies: Insights from the Cognitive Aging Literature -- Clinical Treatment Options and Randomized Clinical Trials for Neurocognitive Complications of HIV Infection: Combination Antiretroviral Therapy, Central Nervous System Penetration Effectiveness, and Adjuvants.
    Abstract: This volume aims at presenting the latest international research and discoveries in the neurocognitive aspects and complications in HIV/AIDS, and how this understanding can shape and inform how we think about clinical practice and patient care in HIV/AIDS as well as lead to a better understanding of the underlying neuropathogenesis. The chapter, "Metabolic Syndrome and Cardiovascular Disease Impacts on the Pathophysiology and Phenotype of HIV-Associated Neurocognitive Disorders", of this book is available open access under a CC BY 4.0 license at link.springer.com.
    Type of Medium: Online Resource
    Pages: XVII, 545 p. 100 illus., 30 illus. in color. , online resource.
    Edition: 1st ed. 2021.
    ISBN: 9783030807597
    Series Statement: Current Topics in Behavioral Neurosciences, 50
    DDC: 571.96
    Language: English
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    Online Resource
    Online Resource
    Cham :Springer International Publishing :
    Keywords: Immunology. ; Pharmacology. ; Biochemical markers. ; Analytical chemistry. ; Biotechnology. ; Immunology. ; Pharmacology. ; Biomarkers. ; Bioanalytical Chemistry. ; Biotechnology.
    Description / Table of Contents: Microheterogeneity of antibody molecules -- Part I: Analytical Methods -- Lectin and LC based methods for immunoglobulin (G) glycosylation analysis -- Mass spectrometry-based methods for immunoglobulin G N-glycosylation analysis -- CE based methods for Ig(G) glycosylation analysis -- Automation of Ig glycosylation analysis -- Bioinformatics in immunoglobulin glycosylation analysis -- Part II: Biosynthesis & Regulation -- N-glycan biosynthesis: Basic principles and factors affecting its outcome -- Genetic regulation of immunoglobulin G glycosylation -- Epigenetics of immunoglobulin G glycosylation -- IgG changes in aging and other inflammatory conditions -- Estrogen-driven changes in immunoglobulin G Fc glycosylation -- Part III: Effector Functions & Diseases -- Sweet rules – linking glycosylation to antibody function -- Immunoglobulin G glycosylation in diseases -- Immunoglobulin A glycosylation and its role in diseases -- Part IV: Applications -- Importance and monitoring of therapeutic immunoglobulin G glycosylation -- Glycosylation of plant-produced immunoglobulins -- The rapidly expanding nexus of immunoglobulin G N-glycomics, suboptimal health status, and precision medicine -- Glycosylation of antigen-specific antibodies - Perspectives on immunoglobulin G glycosylation in vaccination and immunotherapy.
    Abstract: This book summarizes recent advances in antibody glycosylation research. Covering major topics relevant for immunoglobulin glycosylation - analytical methods, biosynthesis and regulation, modulation of effector functions - it provides new perspectives for research and development in the field of therapeutic antibodies, biomarkers, vaccinations, and immunotherapy. Glycans attached to both variable and constant regions of antibodies are known to affect the antibody conformation, stability, and effector functions. Although it focuses on immunoglobulin G (IgG), the most explored antibody in this context, and unravels the natural phenomena resulting from the mixture of IgG glycovariants present in the human body, the book also discusses other classes of human immunoglobulins, as well as immunoglobulins produced in other species and production systems. Further, it reviews the glycoanalytical methods applied to antibodies and addresses a range of less commonly explored topics, such as automatization and bioinformatics aspects of high-throughput antibody glycosylation analysis. Lastly, the book highlights application areas ranging from the ones already benefitting from antibody glycoengineering (such as monoclonal antibody production), to those still in the research stages (such as exploration of antibody glycosylation as a clinical or biological age biomarker), and the potential use of antibody glycosylation in the optimization of vaccine production and immunization protocols. Summarizing the current knowledge on the broad topic of antibody glycosylation and its therapeutic and biomarker potential, this book will appeal to a wide biomedical readership in academia and industry alike. Chapter 4 is available open access under a Creative Commons Attribution 4.0 International License via link.springer.com.
    Type of Medium: Online Resource
    Pages: XII, 591 p. 66 illus., 56 illus. in color. , online resource.
    Edition: 1st ed. 2021.
    ISBN: 9783030769123
    Series Statement: Experientia Supplementum, 112
    DDC: 571.96
    Language: English
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    Online Resource
    Online Resource
    Cham :Springer International Publishing :
    Keywords: Immunology. ; Neurology . ; Neurosciences. ; Diseases. ; Pharmacology. ; Immunology. ; Neurology. ; Neuroscience. ; Diseases. ; Pharmacology.
    Description / Table of Contents: Pro and Anti-Inflammatory Neurovascular Processes in Epilepsy: A Fragile and Dynamic Equilibrium -- Emerging Molecular Mechanisms of Neuroinflammation in Seizure Disorders -- Glial Mechanisms of Inflammation during Seizures -- Perivascular Inflammation and Extracellular Matrix Alterations in Blood-Brain Barrier Dysfunction and Epilepsy -- Blood T cells and Cytokine Levels during Interictal-Ictal Transitions -- Autoantibodies, Encephalopathies and Epilepsy -- Tau Protein in Drug-Resistant Epilepsy and Cognitive Decline -- Ketogenic Diet, Inflammation and Epilepsy -- Role of Regulatory T cells in Epilepsy -- Inflammation at the Neurovascular Unit in Post-Traumatic Epilepsy.
    Abstract: This book provides comprehensive information, both for clinicians and scientists, on the basic mechanisms, clinical features, and therapeutic approaches to epilepsy as an inflammatory disease. Inflammation has been for many years considered as an etiologic player (and a therapeutic target) for a specific group of epilepsies. However, it turns out that this concept underestimated the impact of inflammation in seizure disorders. Many accepted therapies for non-inflammatory epilepsies act in part as an inflammatory drug. The CNS actively responds to acute immune challenges by altering body temperature, stimulating the HPA axis, as well as up- and down-regulating specific sympathetic pathways.
    Type of Medium: Online Resource
    Pages: VIII, 237 p. 1 illus. , online resource.
    Edition: 1st ed. 2021.
    ISBN: 9783030674038
    Series Statement: Progress in Inflammation Research, 88
    DDC: 571.96
    Language: English
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  • 44
    Online Resource
    Online Resource
    Cham :Springer International Publishing :
    Keywords: Immunology. ; Medical sciences. ; Cytology. ; Biochemistry. ; Nutrition   . ; Immunology. ; Health Sciences. ; Cell Biology. ; Biochemistry. ; Nutrition.
    Description / Table of Contents: Prelims -- One-carbon metabolism and development of the conceptus during pregnancy: Lessons from studies with sheep and pigs -- Cell-specific expression of enzymes for serine biosynthesis and glutaminolysis in farm animals -- Amino acids in beef cattle nutrition and production (author to be identified) -- Amino acid nutrition and reproductive performance in ruminants -- Amino acids in the nutrition and production of sheep and goats -- Amino acids in swine nutrition and production -- Amino acid nutrition and metabolism in chickens -- Nutrition and functions of amino acids in fish -- Nutrition and functions of amino acids in aquatic crustaceans -- Amino acids in dog nutrition and health -- Amino acids in the nutrition, metabolism, and health of domestic cats -- Amino acid nutrition for optimum growth, development, reproduction, and health of zoo animals.
    Abstract: This edited volume comprehensively highlights recent advances in the metabolism, nutrition, physiology, and pathobiology of amino acids in companion (dogs and cats), zoo (carnivores, herbivores, and omnivores), and farm (including cattle, pigs, sheep, goats, chickens, fish, and crustaceans) animals. It enables readers to understand the crucial roles of amino acids and their metabolites in the growth, development, health, and metabolic diseases of these animals. Readers will learn from well-written chapters that amino acids are not only the building blocks of protein but are also signaling molecules and key regulators of gene expression and whole body homeostasis in companion, domestic, aquatic, and captive animals. The book also provides new and useful information on the optimum requirements of the animals for dietary amino acids. This knowledge will guide nutritional practices and daily management to improve the health and survival of all species and to enhance the productivity of livestock, poultry, and aquaculture enterprises worldwide to produce high-quality protein for human consumption. Editor of this volume is an internationally recognized expert in the biochemistry, nutrition and physiology of amino acids. He has over 38 years of experience with research and teaching at world-class universities in the area of amino acid biochemistry, nutrition, and physiology. He has published more than 625 papers in peer-reviewed journals, 62 chapters in books, and authored two text/reference books, with an H-index of 117 and more than 55,000 citations in Google Scholar. This publication is a useful reference for professionals and pet owners, as well as undergraduate and graduate students in animal science, aquaculture, zoology, wildlife, veterinary medicine, biology, biochemistry, food science, nutrition, pharmacology, physiology, toxicology, and other related disciplines. In addition, all chapters provide general and specific references to amino acid nutrition and metabolism for researchers and practitioners in animal agriculture, aquaculture, zoos, biomedicine, and plant science, and for government policy makers. Chapter 7 is available open access under a Creative Commons Attribution 4.0 International License via link.springer.com.
    Type of Medium: Online Resource
    Pages: VI, 256 p. 36 illus., 15 illus. in color. , online resource.
    Edition: 1st ed. 2021.
    ISBN: 9783030544621
    Series Statement: Advances in Experimental Medicine and Biology, 1285
    DDC: 571.96
    Language: English
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    Keywords: Ecology . ; Agriculture. ; Zoology. ; Veterinary medicine. ; Epidemiology. ; Ecology. ; Agriculture. ; Zoology. ; Veterinary Science. ; Epidemiology.
    Description / Table of Contents: Part 1 Introduction -- 1 Host Community Interfaces: The Wildlife-Livestock -- 2 Natural And Historical Overview Of The Animal Wildlife-Livestock Interface -- 3 The Ecology Of Pathogens Transmission At The Wildlife-Livestock Interface: Beyond Disease Ecology, Towards Socio-Ecological System Health -- Part 2 Regional Perspectives Of Disease At The Wildlife-Livestock Interface -- 4 Characteristics And Perspectives Of Disease At The Wildlife-Livestock Interface In Europe -- 5 Characteristics And Perspectives Of Disease At The Wildlife-Livestock Interface In Asia -- 6 Characteristics And Perspectives Of Disease At Wildlife-Livestock Interface In Africa -- 7 Characteristics And Perspectives Of Disease At The Wildlife-Livestock Interface In Oceania -- 8 Characteristics And Perspectives Of Disease At The Wildlife-Livestock Interface In North America -- 9 Characteristics And Perspectives Of Disease At The Wildlife-Livestock Interface In Central And South America -- Part 3 Characterization Of The Wildlife-Livestock Interface -- 10 Collecting Data To Assess The Interactions Between Livestock And Wildlife -- 11 Characterization Of Wildlife-Livestock Interfaces: The Need For Interdisciplinary Approaches And A Dedicated Thematic Field -- 12 Quantifying Transmission Between Wild And Domestic Populations -- Part 4 Synthesis And Conclusions -- 13 Synthesis And Future Perspectives Of The Study And Management Of Diseases At The Wildlife-Livestock Interface.
    Abstract: Shared diseases among wildlife, livestock and humans, often transboundary, are relevant to public health and global economy, as being highlighted currently relative to the global COVID19 pandemic. Diseases at these interfaces also impact the conservation of biodiversity and must be considered when managing wildlife. While wildlife and domestic livestock have coexisted in dynamic systems for thousands of years, spillover disease risks are higher today than in the past due to global patterns of increasing close contact and interactions among wildlife, livestock and humans in the context of complex, diverse and numerous circumstances. Multidisciplinary studies of animal interfaces, especially those involving wildlife, therefore, must be brought to the forefront so that knowledge gaps can be realized and filled to inform managers and policy makers. In the first part of the book authors illustrate and discuss ecological and epidemiological concepts related to the interfaces, with a vision towards socio-ecological system health. In addition, the history of past animal interfaces provides the necessary perspective to focus current questions, better understand present situations, and informs how we can best approach the future. The second part discusses the myriad of similar and differing wildlife- livestock interfaces found around the world from a regional point of view. The third part focuses on how to assess the spatial and temporal overlap between livestock and wildlife, and authors present new technical innovations about how inter-transmissions between wild and domestic populations can be quantified. An overview of main modeling approaches available to quantify multi-host disease transmission at the wildlife/livestock interface, illustrated with specific-case studies, is also presented. Finally, the need for interdisciplinary approaches and a dedicated thematic field to approach the wildlife/livestock interfaces and create opportunities to promote wildlife–livestock coexistence is emphasized. The concluding chapter presents perspectives and directions to better understanding disease dynamics at the wildlife/livestock interface, global change and implications for the future. The changing distribution of interfaces, ongoing human and environmental changes (e. g. climate warming, changes in animal production systems, etc.) and their likely impacts and consequences for the interfaces and disease transmission processes are all discussed.
    Type of Medium: Online Resource
    Pages: XVI, 421 p. 77 illus., 64 illus. in color. , online resource.
    Edition: 1st ed. 2021.
    ISBN: 9783030653651
    Series Statement: Wildlife Research Monographs, 3
    DDC: 577
    Language: English
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    Online Resource
    Online Resource
    Cham :Springer International Publishing :
    Keywords: Ecology . ; Life sciences. ; Physiology. ; Biodiversity. ; Biomechanics. ; Biophysics. ; Ecology. ; Life Sciences. ; Physiology. ; Biodiversity. ; Biomechanics. ; Biophysics.
    Description / Table of Contents: High pressure and High pressure environments -- High pressure: molecules, chemical processes and cellular structures -- The high pressure micro-environment of vertebrate load bearing joints- Effects of high pressure on the activity of ordinary animals, including humans, and on the function of their excitable cells and ion channels -- The effects of decompression and subsequent re-compression on the activity of deep sea animals and eukaryote cells. The isobaric collection of deep sea animals.-Molecular adaptation to high pressure: proteins in deep sea animals -- Molecular adaptation to high pressure: membranes -- Prokaryotes at high pressure in the Oceans and the Deep Biosphere -- Hydrothermal vents: the inhabitants, their way of life and their adaptation to high pressure -- Buoyancy at depth -- Divers: Air breathing animals, including humans, at high pressure -- Adaptation to high pressure in the laboratory -- High pressure equipment used in the laboratory, at sea and at depth.
    Abstract: The book discusses the ways in which high hydrostatic pressure (i.e. water pressure) affects all grades of life which thrive at pressures much greater those in our normal environment. The deep sea is the best known high pressure environment, where pressures reach a thousand times greater than those at the surface, yet it is populated by a variety of animals and microorganisms. The earth’s crust supports microorganisms which live in water filled pores at high pressure. In addition, the load bearing joints of animals like ourselves experience pulses of hydrostatic pressure of a magnitude similar to the pressure at mid ocean depths. These pressures affect molecular structures and biochemical reactions. Basic cellular processes are drastically affected – the growth and division of cells, the way nerves conduct impulses and the chemical reactions which provide energy. Adaptation to high pressure also occurs in complex physiological systems such as those which provide buoyancy. Probably the greatest challenge to our understanding of adaptation to high pressure is the stabilisation of the nervous system of deep sea animals to avoid convulsions which pressure causes in shallow water animals. Additionally the book provides insight into the engineering required to study life at high pressure: equipment which can trap small deep sea animals and retrieve them at their high pressure, equivalent equipment for microorganisms, laboratory microscopes which can focus on living cells under high pressure, incubators for bacteria which require high pressure to grow, high pressure aquaria for marine animals and lastly and briefly, manned and unmanned submersible vessels, Landers and deep drill hole sampling. Rather like the organisms studied many laboratory instruments have been adapted to function at high pressure.
    Type of Medium: Online Resource
    Pages: XVII, 445 p. 62 illus., 19 illus. in color. , online resource.
    Edition: 1st ed. 2021.
    ISBN: 9783030675875
    DDC: 577
    Language: English
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    Keywords: Immunology. ; Medical sciences. ; Cytology. ; Biochemistry. ; Nutrition   . ; Immunology. ; Health Sciences. ; Cell Biology. ; Biochemistry. ; Nutrition.
    Description / Table of Contents: Chapter 1: Regulation of Gene Expression by Amino Acids in Animal Cells -- Chapter 2: Amino acids in cell signaling: regulation and function -- Chapter 3: Amino Acids in Endoplasmic Reticulum Stress and Redox Signaling -- Chapter 4: Amino Acids in Autophagy: Regulation and Function -- Chapter 5: Oxidation of Energy Substrates in Tissues of Fish: Metabolic Significance and Implications for Gene Expression and Carcinogenesis -- Chapter 6: Arginine, Agmatine and Polyamines: Key Regulators of Conceptus Development in Mammals -- Chapter 7: Interorgan Metabolism of Glutamate and Glutamine in Poultry -- Chapter 8: Interorgan Metabolism of Amino Acids in Health and Disease -- Chapter 9: Amino Acids and Their Metabolites for Improving Human Exercising Performance -- Chapter 10: Role of L-Arginine in Nitric Oxide Synthesis and Health in Humans -- Chapter 11: Composition of Amino Acids in Foodstuffs for Humans and Animals -- Chapter 12: Dietary Intakes of Amino Acids and Other Nutrients by Adult Humans.
    Abstract: This book explains about amino acids (AAs) which are not only building blocks of protein, but are also signaling molecules as well as regulators of gene expression and the protein phosphorylation cascade. Additionally, AAs are key precursors for syntheses of hormones and low-molecular-weight nitrogenous substances with each having enormous biological importance. For example, physiological concentrations of AA metabolites (e.g., nitric oxide, polyamines, glutathione, taurine, thyroid hormones, and serotonin) are required for cell functions. Growing evidence shows that humans and animals have dietary requirements for all proteinogenic AAs. Mammals, birds, and fish also have species- and age-dependent needs for some AA-related substances. However, elevated levels of other products (e.g., ammonia, homocysteine, H2S, and asymmetric dimethylarginine) are pathogenic factors for neurological disorders, oxidative stress, and cardiovascular disease. Thus, optimal amounts of AAs and their ratios in diets and circulation are crucial for whole-body homeostasis and health. Adequate provision of one or a mixture of functional AAs or metabolites may be beneficial for ameliorating health problems at various stages of the life cycle (e.g., fetal growth restriction, neonatal morbidity and mortality, weaning-associated intestinal dysfunction and wasting syndrome, obesity, diabetes, cardiovascular disease, the metabolic syndrome, and infertility). Dietary supplementation of these nutrients can also optimize the efficiency of metabolic transformations to enhance muscle growth, milk production, and athletic performance, while preventing excess fat deposition and reducing adiposity. Therefore, functional AAs hold great promise in improving the growth, health, and well-being of individuals.
    Type of Medium: Online Resource
    Pages: VI, 227 p. 34 illus., 22 illus. in color. , online resource.
    Edition: 1st ed. 2021.
    ISBN: 9783030741808
    Series Statement: Advances in Experimental Medicine and Biology, 1332
    DDC: 571.96
    Language: English
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    Keywords: Ecology . ; Bioclimatology. ; Environmental sciences Social aspects. ; Risk management. ; Social policy. ; Environment. ; Ecology. ; Climate Change Ecology. ; Environmental Social Sciences. ; IT Risk Management. ; Social Policy. ; Environmental Sciences.
    Description / Table of Contents: Preface and Introduction -- Part I Risks and Impacts Enhancing the Vulnerability of Social-Ecological Systems -- Part II Environmental and Climate Change Impacts on Social-Ecological Systems – Conflict, Inequality and Human Security -- Part III Human Mobility and Social-Ecological Systems -- Part IV Enhancing the Sustainability and Resilience of Social-Ecological Systems – Some Recommended Paths -- Conclusions.
    Abstract: This book contributes to the multidisciplinary debate about social–ecological systems (SES) within the perspective of rethinking the nature of interaction between these systems, especially in the Anthropocene Era. Most chapters either deliberate on risk dynamics threatening current SES or stimulate thought processes to manage such risks and related negative implications. After analyzing the main drivers of SES vulnerability, the book highlights the shifts to be made to enhance the sustainability and resilience of these systems, mainly the integration and restructuring of governance frameworks, the reorganization of production and consumption systems far from conventional models based on consumerism, the elaboration of mitigation, adaptation, and SDGs implementation measures from a co-benefit perspective, and the consideration of appropriate approaches and paradigms while elaborating and implementing response mechanisms. This volume is relevant to researchers/experts, students, practitioners, and decision-makers from different scales and spheres.
    Type of Medium: Online Resource
    Pages: XXXII, 265 p. 43 illus., 39 illus. in color. , online resource.
    Edition: 1st ed. 2021.
    ISBN: 9783030762476
    DDC: 577
    Language: English
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    Online Resource
    Online Resource
    Cham :Springer International Publishing :
    Keywords: Ecology . ; Conservation biology. ; Zoology. ; Biodiversity. ; Ecology. ; Conservation Biology. ; Zoology. ; Biodiversity.
    Description / Table of Contents: Introduction -- Part I. Ethology and Behavioral Ecology of Sea Otters -- Taxonomy and Evolution of Sea Otters -- Sea Otter Behavior: Morphologic, Physiologic, and Sensory Adaptations -- Sea Otter Foraging Behavior -- Social Structure of Marine Otters: Inter and Intraspecific Variation -- Reproductive Behavior of Male Sea Otters -- Reproductive Behavior of Female Sea Otters and Their Pups -- Sea Otter Behavior and Its Influence on Littoral Community Structure -- Sea Otter Predator Avoidance Behavior -- Sea Otters and the Maritime Fur Trade -- Part II. Ethology and Behavioral Ecology of Polar Bears -- Polar Bear Taxonomy and Evolution -- Polar Bear Behavior: Morphologic and Physiologic Adaptations -- Polar Bear Foraging Behavior -- Polar Bear Reproductive and Denning Behavior -- Polar Bear Maternal Care, Neonatal Development, and Social Behavior -- Polar Bear Behavior in Response to Climate Change -- Human-Polar Bear Interactions.
    Abstract: Sea otters and polar bears are carnivorous marine mammals that still resemble their terrestrial ancestors. Compared with Cetacea (whales and dolphins), Sirenia (dugongs and manatees), and Pinnipedia (seals, sea lions, and walrus), they are less adapted for an aquatic life and the most recently evolved among marine mammals. Sea otters are amphibious but seldom come ashore, and polar bears primarily occur on sea ice or along the shore. When at sea, both species spend most of their time swimming at the surface or making short, shallow dives when foraging or pursuing prey. Indeed, polar bears rarely pursue seals in water. Nevertheless, polar bears are powerful swimmers and will stalk seals from the water. As with many other large carnivores, they are solitary hunters. Although sea otters are gregarious and form aggregations at sea called rafts, they are primarily asocial. Except during mating, the principal interaction among sea otters occurs between a female and offspring during the six-month dependency period. In large carnivores (e.g., wolves and lions) that feed on ungulates, sociality and cooperation are favored because of the need to capture large prey and defend carcasses. Polar bears, which are the largest terrestrial carnivore, are solitary hunters of seals and are neither gregarious nor social. Males and females briefly associate during courtship and mating. During this time, males aggressively compete for females. At other times, males generally avoid each other except for aggregations of males that form while summering on land, and females with cubs avoid males, which are known for infanticide. As with sea otters, the interaction of polar bears outside of mating occurs between a female and her offspring during the 2-3 year dependency period. This interaction is critically important when altricial cubs are born in the winter den. This book provides new insight into the ethology and behavioral ecology of sea otters and polar bears. Each chapter reviews the discoveries of previous studies and integrates recent research using new techniques and technology. The authors also address historic and current anthropogenic challenges for their survival as climate change alters entire marine ecosystems.
    Type of Medium: Online Resource
    Pages: XIV, 363 p. 110 illus., 89 illus. in color. , online resource.
    Edition: 1st ed. 2021.
    ISBN: 9783030667962
    Series Statement: Ethology and Behavioral Ecology of Marine Mammals,
    DDC: 577
    Language: English
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    Online Resource
    Online Resource
    Cham :Springer International Publishing :
    Keywords: Immunology. ; Medicine Research. ; Biology Research. ; Biotechnology. ; Immunology. ; Biomedical Research. ; Biotechnology.
    Description / Table of Contents: Western blotting: How it began -- 2. Basics of Western Blotting -- 3.Basic Calculations in Western Blotting -- 4.Choosing The Right Antibody For Western Blotting -- 5. Sample Preparation -- 6. Blocking membranes at places that do not have transferred proteins -- 7. A Basic Method for Western Blotting -- 8. Trouble Shooting Western Blotting -- 9. Using Biotin to demonstrate western and dot blotting in University Practical Classes- A Guide To Instructors -- 10. Nitrocellulose Membrane Art -- 11. The Use Of A Harmless Invisible Ink To Send Secret Messages On Nitrocellulose Membranes And As A Substitute For The Harmful Radioactive Ink Used As A Marker In ECL Membrane Assays -- 12. Fingerprinting On Nitrocellulose And Polyvinylidene Difluoride Membrane -- 13. Spectrometric Determination Of Protein For Electrophoresis -- 14. Concentrating Proteins For Western Blotting -- 15. Dissolving Proteins Using Lysis Buffer -- 16. Blotting And Detecting Glycosaminoglycans -- 17. Passive Blotting From Tissue Slices -- 18. Localizing Proteins by Tissue Printing -- 19. Ultrasound Blotting -- 20. Obtaining Several Blots From A Single SDS-PAGE Gel By Passive Transfer -- 21. Diffusion Blotting From SDS-PAGE Gels Supported By Solid Plastic -- 22. Dot-Immunobinding -- 23. Simultaneous Immunoblotting Analysis With Activity Gel Electrophoresis -- 24. Protein Blotting By Centrifugation -- 25. Blotting And Immunostaining Of Multiple Antigenic Peptides -- 26. High Molecular Weight Protein Blotting Using Agarose Gel Electrophoresis -- 27. Cetyltrimethylammonium bromide PAGE And Eastern Blotting -- 28. Purification Of Autoantibodies Bound To An Autoantigen Immobilized On A Membrane Strip -- 29. Miniaturized Blotting -- 30. Affinity Immunoblotting -- 31. Transferring Coomassie Blue Stained Proteins from Polyacrylamide Gels To Transparencies -- 32. Protein Transfer From Immobilized pH Gradient Gels -- 33. SDS PAGE To Immunoblotting In Sixty Minutes -- 34. Western Blot Analysis Of Protein-DNA Complexes Formed DuringGel Shift Experiments -- 35. Electrophoretic Transfer Of High And Low Molecular Weight Proteins To Membranes Using Heat -- 36. Grid-immunoblotting -- 37. Far-western Blotting -- 38. Native Electrophoresis And Western Blot Analysis -- 39. Efficient Electroblotting Of Low Molecular Weight Protein After Staining With Coomassie -- 40. Avoiding Non-specific Binding Of Secondary Antibodies In Immunoblotting By Double-blotting -- 41.A Brief Introduction To Other Protein Blotting Methods -- 42. Quantitative Computerized Western Blotting In Detail -- 43. Common Problems In Electrophoresis.
    Abstract: This book fills the need for a simplified text covering western blotting protocols aimed not just at high school and college students, but the researcher with little to no experience in these techniques. It provides the principles, basic methodology, and tips and tricks to avoiding the common pitfalls of western blotting. The book also introduces simple protocols that can transform western blotting into a fun method, such as sending secret messages on membranes or using nitrocellulose membrane as a canvas for art. In addition to the techniques, this book also covers the history of western blotting, which originated from the development of the blotting of DNA. It then delves into the importance of protein blotting, brought to the fore by the fact that the procedure has been evolving constantly since its inception in 1979, and the fact that the scientific community is faced with a multitude of ways and means of transferring proteins to membranes.
    Type of Medium: Online Resource
    Pages: XXIII, 467 p. 611 illus., 170 illus. in color. , online resource.
    Edition: 1st ed. 2021.
    ISBN: 9783030706845
    Series Statement: Techniques in Life Science and Biomedicine for the Non-Expert,
    DDC: 571.96
    Language: English
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    Keywords: Biotic communities. ; Freshwater ecology. ; Marine ecology. ; Environmental sciences Social aspects. ; Animal culture. ; Conservation biology. ; Ecology . ; Ecosystems. ; Freshwater and Marine Ecology. ; Environmental Social Sciences. ; Animal Science. ; Conservation Biology.
    Description / Table of Contents: SECTION I. Natural and human environment of coastal ecosystems -- Chapter 1. Ecological modelling and conservation on the coasts of Mexico -- Chapter 2. SE Pacific: the ecosystem and its use along the Chilean and Peruvian coast -- SECTION II. Marine ecosystem models in the South East Pacific coast -- Chapter 3. Modelling the Northern Humboldt Current Ecosystem; from winds to predators -- Chapter 4. Marine ecosystem models in the South Pacific coast -- Chapter 5. Keystone Species Complexes and macroscopic properties for improving ecosystem-based conservation practices in kelp forest along the north-central Chilean coast -- Chapter 6. Exploring alternative management policies for benthic ecological systems of northern Chile (SE Pacific) -- SECTION III. Central Pacific, Caribbean and Atlantic coastal ecosystem models -- Chapter 7. How much biomass must remain at the sea after fishing to conserve ecosystem -- functioning? The case of the Monterey sardine in the Gulf of California, Mexico -- Chapter 8. Dynamic and spatial model of the coral reef of Banco Chinchorro Biosphere Reserve (Caribbean Sea) for assessment harvest scenarios: short-term responses -- Chapter 9. Ecological role of sharks assessed by Ecopath models -- SECTION IV. System-based conservation and management: conclusions -- Chapter 10. Graph theory in food webs: uses and applications for conservation of marine ecosystems -- Chapter 11. Modelling aim the conservation of coastal marine ecosystem in Latin America.
    Abstract: The book presents a collection of large-scale network-modeling studies on coastal systems in Latin America. It includes a novel description of the functioning of coastal complex ecosystems and also predicts how natural and human-made disturbances percolate through the networks. Coastal areas belong to the most populated ecosystems around the globe, and are massively influenced by human impacts such as shipping, mining, fisheries, tourism, pollution and human settlements. Even though many of these activities have facilitated socio-economic development, they have also caused a significant deterioration in natural populations, communities and ecosystems worldwide. Covering coastal marine ecosystems of Latin America such as the NE and SE Pacific, NW Atlantic and Caribbean areas, it discusses the construction of quantitative (Ecopath-Ecosim-Ecospace and Centrality of Node Sets) and semi-quantitative (Loop Analysis) multispecies trophic-network models to describe and assess the impacts of natural and human interventions like pelagic and benthic fishing as well as natural events such as El Niño, and La Niña. The book also features steady state (and/or near moving equilibrium) and dynamical models to support the management of exploited organisms, and applies and quantifies macroscopic indices, based on Ascendency (Ulanowicz) and Local Stability (Levins´ Loop Analysis). Further, it discusses the determination of the Keystone Species Complex Index, which is a holistic extension of the classical concept of Keystone Species (Paine), offering novel strategies for conservation monitoring and management.
    Type of Medium: Online Resource
    Pages: X, 207 p. 41 illus., 3 illus. in color. , online resource.
    Edition: 1st ed. 2021.
    ISBN: 9783030582111
    DDC: 577
    Language: English
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    Online Resource
    Online Resource
    Cham :Springer International Publishing :
    Keywords: Immunology. ; Human physiology. ; Respiratory organs. ; Physiology. ; Immunology. ; Human Physiology. ; Respiratory Physiology.
    Description / Table of Contents: Role of IP3 Receptors in Shaping the Carotid Chemoreceptor Response to Hypoxia but not to Hypercapnia in the Rat Carotid Body: An Evidence Review -- The Role of Hyperbaric Oxygen Treatment for COVID-19: A Review -- Primary Immunodeficiencies - Diseases of Children and Adults: A Review -- Pneumococcal Vaccine in Adult Asthma Patients -- Immunoglobulin G Deficiency in Children with Recurrent Respiratory Infections with and without History of Allergy -- Pruritus Characteristics in Severe Atopic Dermatitis in Adult Patients -- Pathophysiological Responses to a Record-Breaking Multi-Hour Underwater Endurance Performance: A Case Study -- Respiratory Muscle Strength and Ventilatory Function Outcome: Differences between Trained Athletes and Healthy Untrained Persons -- Uroflowmetry and Altitude Hypoxia: A Report from Healthy Italian Trekkers and Nepali Porters during Himalayan Expedition -- Effects of Intraligamentary Injection of Osteogenic-Induced Gingival Fibroblasts on Cementum Thickness in the Dog Model of Tooth Root Resorption -- In-Silico Evaluation of Treatment of Periprosthetic Fractures in Elderly Patients after Hip Arthroplasty -- Appraisal of burden of caregivers to chronically rehabilitated patients with spinal cord injuries in a tertiary neurological center in Nepal.
    Abstract: This book integrates topics in basic research and clinical medicine as well as molecular and cell biology. It presents innovative advances in the field of immunodeficiency syndromes and viral/bacterial respiratory infections, including a novel hyperbaric oxygen treatment for COVID-19. A comprehensive insight is offered into the unresolved molecular pathways in chemosensing that plays a vital role in detecting insufficient tissue oxygenation, as well as in sporting accomplishments. Other articles address cardiorespiratory and humoral responses to hypoxia, the function of cementum in the repair and regeneration of teeth, and periprosthetic fractures following hip arthroplasty in the elderly. The issue of the overwhelming burdens on caregivers to spinal injury patients, damaging both health and psychosocial status, is addressed. The book promotes translation of scientific advances to the general medical practice. It will be a valuable reference for clinical healthcare professionals and researchers interested in innovative practices to improve the prevention, diagnosis, and management of diseases.
    Type of Medium: Online Resource
    Pages: VI, 131 p. 20 illus., 9 illus. in color. , online resource.
    Edition: 1st ed. 2021.
    ISBN: 9783030672164
    Series Statement: Clinical and Experimental Biomedicine, 1289
    DDC: 571.96
    Language: English
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    Online Resource
    Online Resource
    Cham :Springer International Publishing :
    Keywords: Immunology. ; Bioinformatics. ; Immunology. ; Bioinformatics.
    Description / Table of Contents: Cytokine receptor signaling and CD4/CD8 lineage choice during T cell development in the thymus -- An agent-based model of T helper cell fate decisions in the thymus -- Modelling naive T cell homeostasis -- Mechanistic models of CD4 T cell homeostasis and reconstitution in health and disease -- Section 1MODELING THE DYNAMICS OF CD4+ T CELLS IN HIV- 1 INFECTION -- Modelling the response to Interleukin-7 therapy in HIV-infected patients -- Modeling immunopathology during persistent viral infections -- Delay in differentiation may suggest division of labour in models for CD8+ T cell differentiation -- Inferring differentiation order in adaptive immune responses from population level data -- Experimental and mathematical approaches to quantify recirculation kinetics of lymphocytes -- The public face and private lives of T cell receptor repertoires -- Population dynamics of immune repertoires -- Mathematical Modelling of T cell activation -- Agent-based model of heterogeneous T cell activation in vitro -- CTLA-4 mediated ligand trans-endocytosis: a stochastic model -- Automated gating and dimension reduction of high-dimensional cytometry data -- Index.
    Abstract: The purpose of this book is to present current mathematical and computational models that are used to describe and characterise the immunology of T cells. The reader will be exposed to a variety of tools/methods that go hand-in-hand with the T cell-mediated immunological process that is being modelled. We aim in the proposed book to emphasise the role that mathematical (or computational) modelling has already played in Immunology. Each chapter will provide an example of the contribution of mathematics to T cell immunology under one of the following four headings: i) Generation of hypotheses, ii) Quantification of immunological processes, iii) Definition of observables to measure given an experimental objective, iv) reconciling disparate (or even conflicting) experimental results. .
    Type of Medium: Online Resource
    Pages: X, 298 p. 74 illus., 59 illus. in color. , online resource.
    Edition: 1st ed. 2021.
    ISBN: 9783030572044
    DDC: 571.96
    Language: English
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  • 54
    Keywords: Biotic communities. ; Applied ecology. ; Conservation biology. ; Ecology . ; Biodiversity. ; Freshwater ecology. ; Marine ecology. ; Ecosystems. ; Applied Ecology. ; Conservation Biology. ; Biodiversity. ; Freshwater and Marine Ecology.
    Description / Table of Contents: Chapter 1 - Ecosystem services as a tool for decision-making in Patagonia -- Chapter 2- Assessment of provisioning ecosystem services in terrestrial ecosystems of Santa Cruz province, Argentina -- Chapter 3 - Grazing management and provision of ecosystem services in Patagonian arid rangelands -- Chapter 4 - Synergies and trade-offs among ecosystem services and biodiversity in different forest types inside and off-reserve in Tierra del Fuego, Argentina -- Chapter 5 - Shrubland management in northwestern Patagonia: an evaluation of its short-term effects on multiple ecosystem services -- Chapter 6 - Silvopastoral systems in northern Argentine-Chilean Andean Patagonia: Ecosystem services provision in a complex territory -- Chapter 7 - Ecosystem services values of the northwestern Patagonian natural grasslands -- Chapter 8 - The ecosystem services provided by peatlands in Patagonia -- Chapter 9 - Restoration for provision of ecosystem services in Patagonia-Aysén, Chile -- Chapter 10 - The North American beaver invasion and the impact over the ecosystem services in the Tierra del Fuego archipelago -- Chapter 11 - Social links for a nexus approach from an ecosystem services perspective in Central-East Patagonia -- Chapter 12 - Salmon farming: is it possible to relate its impact to the waste remediation ecosystem service? -- Chapter 13 - Using the ecosystem services approach to understand the distributional effects of marine protected areas in the Chilean Patagonia -- Chapter 14 - Socio-cultural valuation of ecosystem services in Southern Patagonia, Argentina -- Chapter 15 - Looking beyond ecosystem services supply: co-production and access barriers in marine ecosystems of the Chilean Patagonia -- Chapter 16 - Ecosystem services and human well-being: a comparison of two Patagonian social-ecological systems -- Chapter 17 - Urban Planning In Arid Northern Patagonia Cities To Maximize Local Ecosystem Services Provision -- Chapter 18 - Land size, native forests and ecosystem services inequalities in the rural Chilean Patagonia -- Chapter 19 - Imaginaries, transformations and resistances in Patagonian territories from a socio-ecological perspective -- Chapter 20 - The challenges of implementing ecosystem services in the Argentinean and Chilean Patagonia -- Chapter 21 - Natural capital and local employment in Argentine Patagonia -- Chapter 22 - Ecosystem services in Patagonia: a synthesis and future directions. .
    Abstract: This book aims to quantify and discuss how societies have directly and indirectly benefited from ecosystem services in Patagonia; not only in terms of provisioning and cultural services, but also regulating and supporting services. Patagonia, a region that stretches across two countries (ca. 10% in Chile and 90% in Argentina), is home to some of the most extensive wilderness areas on our planet. Natural grasslands comprise almost 30% of the Americas, including the Patagonian steppe, while Patagonian southern temperate forests are important for carbon sequestration and storage, play a pivotal role in water regulation, and have become widely recognized for their ecotourism value. However, profound changes are now underway that could affect key ecosystem functions and ultimately human well-being. In this context, one major challenge we face in Patagonia is that ecosystem services are often ignored in economic markets, government policies and land management practices. The book explores the synergies and trade-offs between conservation and economic development as natural landscapes and seascapes continue to degrade in Patagonia. Historically, economic markets have largely focused on the provisioning services (forest products, livestock) while neglecting the interdependent roles of regulating services (erosion and climate control), supporting services (nutrient cycling) and cultural services (recreation, local identity, tourism). Therefore, the present work focuses on ecosystem functions and ecosystem services, as well as on trends in biodiversity and the interactions between natural environments and land-use activities throughout Patagonia.
    Type of Medium: Online Resource
    Pages: VII, 501 p. 85 illus., 58 illus. in color. , online resource.
    Edition: 1st ed. 2021.
    ISBN: 9783030691660
    Series Statement: Natural and Social Sciences of Patagonia,
    DDC: 577
    Language: English
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    Online Resource
    Online Resource
    Cham :Springer International Publishing :
    Keywords: Immunology. ; Human physiology. ; Medicine Research. ; Biology Research. ; Respiratory organs Diseases. ; Immunology. ; Human Physiology. ; Biomedical Research. ; Pneumology.
    Description / Table of Contents: 1. Potential role of mast cells in regulating corticosteroid insensitivity in severe asthma -- 2. Galectin-3 Promotes ROS, Inflammation and Vascular Fibrosis in Pulmonary Arterial Hypertension -- 3. Anti-Inflammatory Effects of Statins in Lung Vascular Pathology: From Basic Science to Clinical Trials -- 4. Evolving Schema for Employing Network Biology Approaches to Understand Pulmonary Hypertension -- 5. Pulmonary Inflammation and KRAS Mutation in Lung Cancer -- 6. microRNA Targets for Asthma Therapy -- 7. Roles of genetic predisposition in the sex-bias of pulmonary pathophysiology, as a function of estrogens -- 8. Hypercapnic respiratory failure-driven skeletal muscle dysfunction: It is time for animal mod-els-based mechanistic research -- 9. Role of airway smooth muscle in inflammation related to asthma and COPD -- 10. Systemic Sclerosis and Pulmonary Disease -- 11. Innate Lymphoid Cells in airway inflammation -- 12. Sjogren’s Syndrome and pulmonary disease -- 13. Redox Regulation, Oxidative Stress and Inflammation in Group 3 Pulmonary Hypertension -- 14. Sex-Steroid Signaling in Lung Diseases and Inflammation -- 15. Cytokines, Chemokines and Inflammation in Pulmonary Arterial Hypertension -- 16. Interactive roles of CaMKII/Ryanodine Receptor Signaling and Inflammation in Lung Diseases -- 17. Reciprocal Correlations of Inflammatory and Calcium Signaling in Asthma Pathogenesis -- 18. Crosstalk between Lung and Extrapulmonary Organs in Infection and Inflammation -- 19. Inflammation in Pulmonary Arterial Hypertension -- 20. Lysophospholids in Lung Inflammatory Diseases.
    Abstract: Respiratory diseases are leading causes of death and disability globally, with about 65 million people suffering from COPD, and 334 million from asthma, the most common chronic disease. Each year, tens of millions of people develop and can die from respiratory infections such as pneumonia and TB. Systemic inflammation may induce and exacerbate local inflammatory diseases in the lungs, and local inflammation can in turn cause systemic inflammation. There is increasing evidence of the coexistence of systemic and local inflammation in patients suffering from asthma, COPD, and other lung diseases, and the co-morbidity of two or more local inflammatory diseases often occurs. For example, rheumatoid arthritis frequently occurs together with, and promotes the development of, pulmonary hypertension. This co-morbidity significantly impacts quality of life, and can result in death for those affected. Current treatment options for lung diseases are neither always effective, nor often condition-specific; there is a desperate need for novel therapeutics in the field. Additionally, the molecular and physiological significance of most major lung diseases are not well understood, which further impedes development of new treatments, especially in the case of coexistent lung diseases with other inflammatory diseases. Great progress has been made in recent years in many areas of the field, particularly in understanding the molecular geneses, regulatory mechanisms, signalling pathways, and cellular processes within lung diseases, as well as basic and clinical technology, drug discovery, diagnoses, treatment options, and predictive prognoses. This is the first text to aggregate these developments. In two comprehensive volumes, experts from all over the world present state-of-the-art advances in the study of lung inflammation in health and disease. Contributing authors cover well-known as well as emerging topics in basic, translational, and clinical research, with the aim of providing researchers, clinicians, professionals, fellows, and students with new perspectives and concepts. The editor hopes this book will also help to direct future research in lung disease and other inflammatory diseases, and result in the development of novel therapeutics.
    Type of Medium: Online Resource
    Pages: XV, 409 p. 54 illus., 38 illus. in color. , online resource.
    Edition: 1st ed. 2021.
    ISBN: 9783030630461
    Series Statement: Advances in Experimental Medicine and Biology, 1303
    DDC: 571.96
    Language: English
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    Online Resource
    Online Resource
    Cham :Springer International Publishing :
    Keywords: Immunology. ; Medicine Research. ; Biology Research. ; Cytokines. ; Immunology. ; Biomedical Research. ; Cytokines and Growth Factors.
    Description / Table of Contents: Advances in translational science to identify new therapies for systemic lupus erythematosus -- Hallmark of systemic lupus erythematosus: Role of B Cell Hyperactivity. Fabien B Vincent, William A Figgett and Margaret L Hibbs -- B cell targeted therapies in systemic lupus erythematosus -- Type I Interferons and the perpetuation of a loss of tolerance -- Therapeutic Modulation of the Interferon Pathway in Systemic Lupus Erythematosus -- The concept of co-stimulatory blockade in SLE -- Cytokines: their role in amplifying SLE pathogenesis -- Intracellular targets in SLE -- Regulatory T cells in SLE -- Balancing strategies: GC and GILZ Axis.
    Abstract: The scope of this contributed volume is to provide an overview of the latest translational research in the field of lupus pathogenesis, with particular emphasis on how these discoveries progress in parallel with therapeutic drug development. Systemic lupus erythematosus (SLE) is a multifaceted disease with a number of well-defined immune pathways that are dysregulated, resulting in an immune-mediated chronic inflammatory injury at target organs. As knowledge of these pathways evolves to provide opportunities for targeted drug therapy and lays the foundation for personalized medicine, clinicians and researchers need to keep up with the ever-expanding medical literature. This book will critically appraise the current understanding of important immunological pathways that contribute to the pathogenesis of lupus. We will review the role of interferons as part of the innate immune defects that perpetuate the loss of self-tolerance in SLE. B cell hyperactivity, as a defining hallmark of SLE, and different strategies of B cell targeted therapy will be discussed. The role of co-stimulation or immune checkpoint molecules in activating B and T cells will be reviewed, as well as other cytokines that serve in the amplification loop promoting a more proinflammatory Th1 or Th17 responses. Intracellular targets, such as signaling molecules in the JAK/STAT pathway, or a variety of kinases and proteasomes, can cause a cascading downstream effect of transcriptional responses that are important in SLE. Immune homeostasis can also be restored by bolstering the naturally occurring anti-inflammatory mechanisms. Glucocorticoid, as a potent natural anti-inflammatory hormone, can mediate its effects by recruiting histone deacetylase that serve to repress gene transcription. Glucocorticoid-induced leucine zipper is a gene upregulated by glucocorticoid that can be a potential target for development of anti-inflammatory strategy. Finally, T regulatory cells can be utilized to help restore to immune tolerance and are amongst the latest focus of therapeutic development in SLE.
    Type of Medium: Online Resource
    Pages: XXI, 178 p. 36 illus., 24 illus. in color. , online resource.
    Edition: 1st ed. 2021.
    ISBN: 9783030851613
    DDC: 571.96
    Language: English
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    Keywords: Immunology. ; Medical microbiology. ; Proteins . ; Immunology. ; Medical Microbiology. ; Protein Biochemistry.
    Description / Table of Contents: 1. Discovering the role of mannose-binding lectin (MBL) in innate immunity: the early history -- 2. Mannose-binding lectin in human health and disease -- 3. The activities of MASPs, complement proteases associated with collectins and ficolins -- 4. Structures of the MASPs and comparison with C1r and C1s -- 5. Biological activities of SP-A and SP-D against extracellular and intracellular pathogens -- 6. Surfactant protein D: A Therapeutic Target for Allergic Airway Diseases -- 7. SP-D in immune surveillance against cancer -- 8.Testicular immune privilege – a recently discovered domain of Collectins -- 9. Role of Collectins in Pregnancy -- 10. Bovine Collectins: Role in Health and Disease -- .
    Abstract: The topic of this book, Collectins, is a family of proteins whose major function is in innate immunity, where Collectins act as pattern recognition receptors (PRRs). In general they recognize targets such as microbial surfaces and apoptotic cells, and once bound to a target, Collectins promote the clearance of microorganisms and damaged host tissue. New cell-surface proteins and glycoproteins, which act as Collectin receptors, are currently being identified. Some Collectins, particularly MBL, activate the complement system, which enhances the ability of antibodies to fight pathogens, via three MBL-associated proteases, the MASPs. Additionally, recent research has begun to show wider-ranging activities of Collectins, such as: · Their role in metabolism, and therefore their involvement in lifestyle diseases such as obesity and cardiovascular disease. · Their ability to modulate the adaptive immune response, as well as to recognize and trigger apoptosis of cancer cells, which makes them effective in the annihilation of cancer cells with multiple mutations. · The regulation of their expression by gonadal steroid hormones implicates them with critical roles in both male and female fertility. · Altered levels of Collectins have been associated with various autoimmune diseases. This book brings together current knowledge of the structure, functions and biological activities of Collectins, to describe their integral role in human health.
    Type of Medium: Online Resource
    Pages: XII, 244 p. 50 illus., 45 illus. in color. , online resource.
    Edition: 1st ed. 2021.
    ISBN: 9783030670481
    DDC: 571.96
    Language: English
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    Keywords: Immunology. ; Alternative medicine. ; Virology. ; Therapeutics. ; Nutrition   . ; Food science. ; Immunology. ; Complementary and Alternative Medicine. ; Virology. ; Therapeutics. ; Nutrition. ; Food Science.
    Description / Table of Contents: 1. Introduction to COVID-19 -- 2. Medicinal plants as COVID-19 remedy -- 3. Traditional Chinese Medicines as possibly remedy Against SARS- CoV-2 -- 4. Plant natural products against COVID-19 -- 5. Foods as first defense against COVID-19 -- 6. Drugs for the treatment of COVID-19 -- 7. COVID-19 pandemic and vaccines -- 8. Recent updates in vaccine development against COVID-19 -- 9. Recent developments in therapeutic approaches against COVID-19.
    Abstract: This research volume examines the available alternative, complementary, pharmaceutical and vaccine methods for treating, mitigating, or preventing COVID-19. Coverage includes traditional Chinese medicine, herbal remedies, nutraceutical/dietary options, and drug/vaccine therapies. All the methods discussed will be critically examined to provide readers with a full, unbiased overview that includes pros/cons of each method. While the nature of COVID-19 is still being studied, and new research and theories are being published daily, this book endeavors to provide readers with a comprehensive summary of current research on alternative and mainstream treatment and prevention methods. .
    Type of Medium: Online Resource
    Pages: XII, 284 p. 120 illus., 68 illus. in color. , online resource.
    Edition: 1st ed. 2021.
    ISBN: 9783030679897
    DDC: 571.96
    Language: English
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    Keywords: Immunology. ; Diseases. ; Therapeutics. ; Immunology. ; Diseases. ; Therapeutics.
    Description / Table of Contents: Section 1: Introduction -- Chapter 1: Introduction: An overview of host-directed therapies for tuberculosis -- Section 2: Targeting immunometabolism -- Chapter 2: Sirtuin deacetylases: Linking Mycobacterial infection and host metabolism -- Chapter 3:The mammalian target of rapamycin complex 1 (mTORC1): an ally of M. tuberculosis in host cells -- Chapter 4: HIF-1α as a potential therapeutic target for tuberculosis treatment -- Chapter 5: Nuclear receptors in host-directed therapies against tuberculosis -- Section 3: Enhancing anti-mycobacterial mechanisms -- Chapter 6: Autophagy as a target for host-directed therapy against tuberculosis -- Chapter 7: Metformin: a leading HDT candidate for TB -- Chapter 8: Statins as host-directed therapy for tuberculosis -- Chapter 9: Antimycobacterial attributes of mitochondria: An insight into host defense mechanisms -- Section 4: Targeting immune cells -- Chapter 10: Conventional and unconventional lymphocytes in immunity against Mycobacterium tuberculosis -- Chapter 11: Targeting inhibitory cells such as Tregs and MDSCs in the tuberculous granuloma -- Chapter 12: Targeting suppressor T cells -- Chapter 13: Neutrophil-mediated mechanisms as targets for host-directed therapies against tuberculosis -- Chapter 14: Type I interferon and interleukin-1 driven inflammatory pathways as targets for HDT in tuberculosis -- Chapter 15: Mucosal-associated invariant and Vγ9Vδ2 T cells -- Chapter 16: Airway epithelial cells.-Section 5: Preclinical models for assessing HDTs -- Chapter 17: In vitro models of human granuloma formation to analyze host-directed therapies -- Chapter 18: C3HeB/FeJ as a key mouse strain for testing host-directed therapies against tuberculosis -- Chapter 19: The Rabbit Model for Assessing Host-Directed Therapies for Tuberculosis -- Section 6: Clinical trials of HDTs and special considerations for study endpoints -- Chapter 20:Clinical trials of TB-HDT candidates -- Chapter 21:Outcomes for clinical trials of host-directed therapies for tuberculosis -- Chapter 22: Pharmacological considerations for clinical trials of host-directed therapies for tuberculosis.
    Abstract: This book discusses specific immune cell regulatory pathway(s), immune cell types, or other mechanisms involved in host responses to tuberculosis that can be potentially targeted for host-directed therapy (HDT). The pathways/mechanisms investigated are either protective – thus calling for pathway/factor enhancing drugs – or maladaptive – thus calling for pathway/factor inhibitory drugs. Discovery and development (pre-clinical and clinical) of candidate HDT agents will also be elucidated, as well as approaches for HDT of other diseases. The benefit to the reader will derive from learning about the biology of multiple host pathways involved in health and disease, how these pathways are disrupted or dysregulated during tuberculosis, and which druggable targets exist in these pathways. This book provides the reader with a roadmap of current and future directions of HDT against tuberculosis. Since the host pathways/factors involved in protective or maladaptive responses to tuberculosis are not disease-specific, information learned from the context of tuberculosis likely will be relevant to other infectious and non-infectious diseases.
    Type of Medium: Online Resource
    Pages: XIII, 332 p. 20 illus. , online resource.
    Edition: 1st ed. 2021.
    ISBN: 9783030569051
    DDC: 571.96
    Language: English
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    Keywords: Immunology. ; Medical sciences. ; Virology. ; Diseases. ; Patient education. ; Immunology. ; Health Sciences. ; Virology. ; Diseases. ; Patient Education.
    Description / Table of Contents: 1. Microbes and infectious diseases -- 2. Acne -- 3. Skin abscesses (boils) -- 4. Dandruff -- 5. Fungal nail infections -- 6. Fungal infections of the skin -- 7. Chickenpox -- 8. Shingles -- 9. Common warts -- 10. The common cold -- 11. Influenza -- 12. Sore throat -- 13. Coronavirus disease-2019 -- 14. Acute sinusitis -- 15. Chronic sinusitis -- 16. Otitis media (middle ear infection) -- 17. Otitis externa (swimmers ear) -- 18. Acute bronchitis (chest cold) -- 19. Conjunctivitis (pink eye) -- 20. Tooth decay (caries) -- 21. Gum disease -- 22. Bad breath -- 23. Oral thrush -- 24. Oral herpes -- 25. Cystitis (lower urinary tract infection) -- 26. Vaginitis -- 27. Chlamydia -- 28. Gonorrhoea -- 29. Genital herpes -- 30. Genital warts -- 31. Syphilis -- 32. Gastroenteritis due to Campylobacter -- 33. Gastroenteritis due to Salmonella -- 34. Gastroenteritis due to Clostridium perfringens -- 35. Gastroenteritis due to Norovirus -- 36. Gastroenteritis due to Rotavirus.
    Abstract: Microbes – can’t live with them, can’t live without them. Increasingly, we’re finding out that our microbiota (the microbes that live on us) are essential for our wellbeing – they provide us with nutrients and vitamins and play a key role in developing our immune system. On the other hand, they are responsible for a great deal of misery, as they are major causes of death and debility around the world. As well as our own microbiota turning against us, there are lots of other microbes out in the wider world that can seriously damage, or even kill, those they infect. The current pandemic of COVID-19 shows the devastating effect that an infectious disease can have – our lives have been turned upside down. If you live in a developed country, you’re not likely to get killer diseases such as ebola and cholera, but you do have a high chance of catching other infections that can have a significant impact on your wellbeing. This book focuses on those infections you’re most likely to go down with, and supplies the answers to the following questions about them: Which infectious diseases are we likely to come across? How common are they? What microbes cause them? What happens to our bodies during an infection? How are the resulting illnesses treated? How can we avoid getting them? This book covers nearly 60 infectious diseases that people living in developed countries are likely to experience at some point during their life. It also has an introductory chapter that describes, in everyday language, the basic principles of microbiology and infectious diseases. Each chapter is lavishly illustrated, has interesting, relevant inserts, and provides a list of web-accessible suggestions for further reading.
    Type of Medium: Online Resource
    Pages: XV, 526 p. , online resource.
    Edition: 1st ed. 2021.
    ISBN: 9783030569785
    DDC: 571.96
    Language: English
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    Online Resource
    Online Resource
    Cham :Springer International Publishing :
    Keywords: Biotic communities. ; Forestry. ; Applied ecology. ; Plant ecology. ; Ecosystems. ; Forestry. ; Applied Ecology. ; Plant Ecology.
    Description / Table of Contents: Foreword -- Preface -- PART I: Evolution, genetics and distribution -- 1. Phylogenesis and evolution -- 2. Population genetics and genomics -- 3. Conservation and breeding -- 4 Biogeography and local adaptations -- 5. Mediterranean pines as invasive species -- PART II: Ecophysiology of Mediterranean pines: resistance to stress and perturbation -- 6. Physiological trade-offs under stress and perturbation -- 7. Carbon allocation dynamics under stress -- 8 -- Root systems under drought -- 9. Stress and tree mortality -- 10. Forest diseases affecting pines -- 11. Resistance to herbivorous insects -- PART III: Pine and mixed forest ecosystems under global climate change -- 12. Growth and vigor -- 13. Forest distribution resilience under climate change -- 14. Carbon and energy balance -- 15. Soil properties and biogeochemical functioning -- 16. Decomposition -- PART IV: Forest dynamics, biodiversity and biotic interactions -- 17. Dynamics of mixed pine-oak forests -- 18. Bird diversity -- 19 Soil micro- and macrofauna -- 20. Mycorhizae -- PART V: Forest fire ecology and management -- 21. Fire past present and future -- 22. Adaptations to fire -- 23. Post-fire soil erosion -- 24. The impact of grazing on understory fuel load -- 25. Post fire restoration -- 26. Predicting post-fire conifer regeneration in California -- 27. Remote sensing fire damage -- PART VI: Policy and Ecosystem services of Mediterranean pine and mixed forest ecosystems -- 28. Mediterranean forests and the United Nations sustainable development goals -- 29. Ecosystem services -- 30.Multi-disciplinary assessment of cultural ecosystem services supplied by Mediterranean pine and mixed forests -- PART VII: Afforestation and forest management policy -- 31. Dynamics and management of western Mediterranean pinewoods -- 32. From pine monoculture forests into sustainable mixed forest ecosystems -- 33. Forest policy in Israel -- 34. Water based forest management.
    Abstract: Almost 20 years after the first MEDPINE book "Ecology, biogeography and management of Pinus halepensis and P. brutia forest ecosystems in the Mediterranean basin "(Ne'eman and Trabaud, 2000) was published, this new book presents up to date and state of the art scientific knowledge and information. It covers a wide range of topics concerning Mediterranean pine trees growing in natural and planted forests, their ecosystems and management. This book will be an essential source for learning, exploring, planning and managing Mediterranean pine and mixed pine-broadleaved forests. It includes mostly review chapters contributed by leading scientists, foresters and managers. It covers: genetics and adaptation, distribution and evolution, ecophysiology and drought resistance, function of pine and mixed forest ecosystems, forest dynamics, biodiversity and biotic interactions, fire ecology, afforestation and management, ecosystem services and policy - all under the effect of global climate change. While forests are studied mainly in temperate and tropical climate zones, looking at Mediterranean forests of sub-humid to semi-arid regions is important more than ever due to current global climate trends. This collection can serve as a scientific textbook for students of biology, agriculture and forestry, researchers of ecology, forestry and related fields, forest managers, policy and decision makers.
    Type of Medium: Online Resource
    Pages: XXIII, 746 p. 185 illus., 129 illus. in color. , online resource.
    Edition: 1st ed. 2021.
    ISBN: 9783030636258
    Series Statement: Managing Forest Ecosystems, 38
    DDC: 577
    Language: English
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    Online Resource
    Cham :Springer International Publishing :
    Keywords: Immunology. ; Pharmacology. ; Internal medicine. ; Immunology. ; Pharmacology. ; Internal Medicine.
    Description / Table of Contents: 1.Human Papillomavirus-associated cancers -- 2. Mechanisms of immune evasion by Ebola virus -- 3. Innate immune mechanisms against HIV-1 -- 4. Current insights into the host immune response to respiratory viral infections -- 5. Immune responses to MERS-CoV in humans and animals -- 6. SARS-CoV-2: Pathogenesis and host-pathogen interaction -- 7. Antibiotic Resistance mechanisms and their transmission in Acinetobacter baumannii -- 8. Pathogenesis and host immune response in leprosy -- 9. Innate immunity and tuberculosis -- 10. Vaccination strategies against Mycobacterium tuberculosis: BCG and beyond -- 11. Candida pathogenicity and interplay with the immune system -- 12. Immune responses in Malaria and vaccine strategies.
    Abstract: This book updates in detail the microbial pathogenesis of various important pathogens, including HIV-1, MERS, SARS-CoV-2, Mycobacterium and Plasmodium. There is also a general discussion of the innate and adaptive immune responses against primary and opportunistic infections. The overall purpose of the book is to aid in the development of anti-viral and anti-microbial targets.
    Type of Medium: Online Resource
    Pages: XIII, 291 p. 35 illus., 33 illus. in color. , online resource.
    Edition: 2nd ed. 2021.
    ISBN: 9783030674526
    Series Statement: Advances in Experimental Medicine and Biology, 1313
    DDC: 571.96
    Language: English
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    Online Resource
    Online Resource
    Cham :Springer International Publishing :
    Keywords: Biotic communities. ; Biodiversity. ; Plant ecology. ; Animal migration. ; Ecosystems. ; Biodiversity. ; Plant Ecology. ; Animal Migration.
    Description / Table of Contents: 1. Introduction: Randall W. Myster -- 2. Dynamics of Andean Treeline Ecotones: Between Cloud Forest and Páramo Geocritical Tropes. Fausto O. Sarmiento -- 3. ANÁLISIS REGIONAL EN ECOSISTEMAS DE MONTAÑA EN COLOMBIA:Una mirada desde la funcionalidad del paisaje y los servicios ecosistémicos. Paola Isaacs-Cubides, Julián Díaz and Tobias Leyva-Pinto -- 4. Ecohydrology of Tropical Andean Cloud Forests. Conrado Tobon Martin -- 5. Litterfall in Andean forests: Quantity, composition, and environmental drivers. Wolfgang Wilcke -- 6. Arbuscular Mycorrhizal Fungi and Ectomycorrhizas in the Andean Cloud Forest of South Ecuador. Ingeborg Haug, Sabrina Setaro, Juan Pablo Suárez -- 7. Nesting ecology of the Tucuman Amazon (Amazona tucumana) in the cloud forest of Northwestern Argentina. Luis Rivera and Natalia Politi -- 8. Adaptive strategies of frugivore bats to Andean cloud forests. Adriana Ruiz and Pascual J. Soriano -- 9. Diversification and dispersal of Neotropical fauna: Processes and patterns in Andean species diversity. Juan C. Garcia-Ramirez and Angela M. Mendoza-Henao -- 10. Mapping Hydrological Ecosystem Services and Impacts of Scenarios for Deforestation and Conservation of Lowland, Montane and Cloud-Affected Forests. Mark Mulligan -- 11. Randall W. Myster. Conclusions, synthesis and future directions.
    Abstract: A book focused solely on Andean Cloud Forests (ACF) has never been published. ACF are high biodiversity ecosystems in the Neotropics with a large proportion of endemic species, and are important for the hydrology of entire regions. They provide water for large parts of the Amazon basin, for example. Here I take advantage of my many years working in ACF in Ecuador, to edit this book that contains the following sections: (1) ACF over space and time, (2) Hydrology, (3) Light and the Carbon cycle, (4) Soil, litter, fungi and nutrient cycling, (5) Plants, (6) Animals, and (7) Human impacts and management. Under this premise, international experts contributed chapters that consist of reviews of what is known about their topic, of what research they have done, and of what needs to be done in the future. This work is suitable for graduate students, professors, scientists, and researcher-oriented managers.
    Type of Medium: Online Resource
    Pages: X, 223 p. 61 illus., 43 illus. in color. , online resource.
    Edition: 1st ed. 2021.
    ISBN: 9783030573447
    DDC: 577
    Language: English
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    Keywords: Immunology. ; Bioinformatics. ; Immunology. ; Bioinformatics.
    Description / Table of Contents: 1. An Overview of the Translational Dilemma and the Need for Model-based Precision Medicine -- 2 Translational Equation-based Modeling -- 3. Agent-based Modeling in Translational Systems Biology -- 4. Integrating Data-driven and Mechanistic Modeling in Sepsis and Trauma -- 5. Therapeutics as Control: Model-based approaches for control discovery -- 6. Disorder of Systemic Inflammation in Sepsis and Trauma: A Systems Perspective -- 7. Multi-scale equation-based models: Insights for Inflammation and Physiological Variability -- 8. In silico Trials and Personalized Therapy for Sepsis and Trauma -- 9. Computational Modeling of the Coagulation Response -- 10. Disorder of Localized Inflammation in Wound Healing -- 11. Equation-based Models of Wound Healing and Collective Cell Migration -- 12. Agent-based Models of Wound Healing -- 13. Tissue realistic translational modeling of gut inflammation -- 14. Data-Driven Modeling of Liver Injury, Inflammation, and Fibrosis -- 15. Computational Modeling of Tuberculosis -- 16. The Rationale and Implementation of Model-based Precision Medicine for Inflammatory Diseases -- Index.
    Abstract: This second edition expands upon and updates the vital research covered in its predecessor, by presenting state-of-the-art multidisciplinary and systems-oriented approaches to complex diseases arising from and driven by the acute inflammatory response. The chapters in this volume provide an introduction to different types of computational modeling, and how these methods can be applied to specific inflammatory diseases, with a focus on providing readers a roadmap for integrating advanced mathematical and computational techniques with traditional experimental methods. In this second edition, we cover both well-established and emerging modeling methods, especially state-of-the-art machine learning approaches and the integration of data-driven and mechanistic modeling. This volume introduces the concept of Model-based Precision Medicine as an alternative approach to the current view of Precision Medicine, based on leveraging mechanistic computational modeling to decrease cost while increasing the information value of the data being obtained. By presenting the role of computational modeling as an integrated component of the research process, Complex Systems and Computational Biology Approaches to Acute Inflammation: A Framework for Model-based Precision Medicine offers a window into the recent past, the present, and the future of computationally-augmented biomedical research.
    Type of Medium: Online Resource
    Pages: IX, 312 p. 51 illus., 37 illus. in color. , online resource.
    Edition: 2nd ed. 2021.
    ISBN: 9783030565107
    DDC: 571.96
    Language: English
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    Online Resource
    Cham :Springer International Publishing :
    Keywords: Ecology . ; Conservation biology. ; Water. ; Hydrology. ; Biotic communities. ; Oceanography. ; Ecology. ; Conservation Biology. ; Water. ; Ecosystems. ; Ocean Sciences.
    Abstract: The Arabian Seas Marine Region encompasses marine areas from Djibouti to Pakistan, including the northern part of Somalia, the Red Sea, the Arabian/Persian Gulf, and parts of the Arabian Sea. Human pressures on the coastal and marine environments are evident throughout the region, and have resulted in harmful environmental effects. Oil and domestic, urban and industrial pollutants in several areas of this part of the world have caused local habitat degradation, eutrophication and algal blooms. Further, coastal landfill, dredging, and sedimentation, as well as nutrient and sediment runoff from phosphate mining, agriculture and grazing, and reduction in freshwater seepage due to groundwater extraction are all contributing to the degradation of coastal environments. This book discusses aspects not covered in other books on the region, which largely focus on marine biodiversity, and examines several environmental challenges that are often ignored, but which have a significant impact on the environment. Evaluating the status quo, it also recommends conservation measures and examines the abiotic factors that play a major main role in the environmental changes. Lastly, the book addresses the biodiversity of the area, providing a general context for the conservation and management measures discussed.
    Type of Medium: Online Resource
    Pages: XXV, 1377 p. 410 illus., 262 illus. in color. , online resource.
    Edition: 1st ed. 2021.
    ISBN: 9783030515065
    DDC: 577
    Language: English
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    Online Resource
    Online Resource
    Cham :Springer International Publishing :
    Keywords: Immunology. ; Medicine Research. ; Biology Research. ; Immunology. ; Biomedical Research.
    Description / Table of Contents: Part I: Overview of Immunity -- Ch 1: Immunity -- Ch 2: Components of immunity -- Ch 3: Hematopoiesis -- Ch 4: The Immune system: pathogen sensing and detection -- Ch 5: Lymphoid organs -- Ch 6: Innate and Adaptive immunity -- Ch 7: Leukocyte homing, migration and recirculation -- Ch 8: Apoptosis -- Ch 9: Antigens -- Ch 10: B cell development, activation and immunoglobulin structure -- Ch 11: Immunoglobulin and T cell receptor gene rearrangements -- Ch 12: Major histocompatibility complex proteins -- Ch 13: T cell development and T cell receptor structure -- Ch 14: Cytokines -- Ch 15: Lymphocyte signals -- Ch 16: Complement fixation -- Ch 17: Cell mediated immunity -- Ch 18: Hypersensitivities -- Ch 19: Parasite Immunity -- Ch 20: Vaccines -- Ch 21: Transplantation -- Ch 22: Immune regulation and autoimmunity -- Ch 23: Immunodeficiencies -- Ch 24: Cancer -- Ch 25: Practice questions -- Ch 26: Study guide for exam. Part II. Laboratory Manual -- 27. Immunology laboratory policies -- 28. Instructions for notebook entries -- 29. Instructions for writing lab reports -- 30. Lab report topics -- 31. Exercise 1: Using a compound microscope -- 32. Exercise 2: Pipetting and dilution technique, identification of mouse lymphoid organs -- 33. Exercise 3: Blood Cell Preparation, Leukocyte differentiation and ABO Blood Typing -- 34. Exercise 4: Single Suspension of Mouse Spleen cells, Cell Viability Assays, and Identification of specific cells using surface antigens -- 35. Exercise 5: Isolation of mouse peritoneal macrophages: In vitro phagocytosis of bacterial cells -- 36. Exercise 6: Clearance of bacteria from mouse blood by the RES -- 37. Exercise 7: Hemolytic Plaque assay (The Jeme Plaque Assay) -- 38. EXERCISE 8: Rabbit and Mouse Immunizations- Preparation of Polyclonal antibodies and screening assays -- 39. EXERCISE 9: Determination of Antibody Titer: Screening Techniques -- 40. EXERCISE 10: Immunodiffusion and Immunoelectrophoresis -- 41. EXERCISE 11: Protein Affinity Purification of Rabbit IgG -- 42. EXERCISE 12: Sodium Dodecyl Sulfate Polyacrylamide Gel Electrophoresis (SDS-PAGE) -- 43. EXERCISE 13: Immunoblotting (Western Blotting) -- 44. Exercise 14: Protein Assay -- 45. Exercise 15: Enzyme-linked Immunosorbent Assay (ELISA) -- 46. EXERCISE 16: Enzyme-Linked Immunospot Assay (ELISPOT) -- 47. EXERCISE 17: Immunofluorescence assay (IFA) -- 48. EXERCISE 18: Flow Cytometry -- 49.EXERCISE 19: Complement Fixation Assays -- 50. Tissue Cell Culture Techniques -- 51. EXERCISE 20: Mitogen Induced Response of Lymphocytes: Detection of Band T cell Lymphocytes Using Immunofluorescence -- 52. Exercise 21: Induction of IL-2 Secretion from Mouse Lymphoma Cells -- 53. EXERCISE 22: Adoptive Transfer of Lymphocytes: Band T cell Cooperation for Antibody Production -- 54. EXERCISE 23: Macrophage Migration Inhibition -- 55. EXERCISE 24: Monoclonal Antibody Preparation -- 56. EXERCISE 25: Immunization of mice with a recombinant protein -- 57. EXERCISE 26: Polarization of T helper cells into TH1 subset -- 58. Exercise 27: Immunoprecipitation -- 59. EXERCISE 28: Induction of apoptosis in T lymphocytes and detection of apoptotic markers -- 60. EXERCISE 29: Cloning and sequencing of cDNAs of mouse variable regions of H and L chains of monoclonal antibodies -- Appendix -- Sample Practice Questions.
    Abstract: A two-in-one text providing teaching lab students with an overview of immunology as well as a lab manual complete with current standard exercises. Section I of this book provides an overview of the immune system and immunity, and includes review questions, problem sets, case studies, inquiry-based questions, and more to provide students with a strong foundation in the field. Section II consists of twenty-two lab exercises focused on key concepts in immunology, such as antibody production, cell separation, cell function, immunoassays, Th1/Th2 cytokine detection, cell and tissue culture methods, and cell and molecular biology techniques. Appendices include safety information, suggested links and readings, and standard discipline processes, protocols, and instructions.
    Type of Medium: Online Resource
    Pages: XX, 471 p. 61 illus., 26 illus. in color. , online resource.
    Edition: 1st ed. 2021.
    ISBN: 9783030646868
    DDC: 571.96
    Language: English
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    Keywords: Ecology . ; Biotic communities. ; Biodiversity. ; Water. ; Hydrology. ; Ecology. ; Ecosystems. ; Biodiversity. ; Water.
    Description / Table of Contents: Chapter 1: Introduction -- Chapter 2: Regional context and maritime governance -- Chapter 3: Alboran Sea area climate and weather -- Chapter 4: The Oceanographic and climatic context -- Chapter 5: A Geological history for the Alboran Sea region -- Chapter 6: Seafloor morphology and processes in the Alboran Sea -- Chapter 7: The biogeochemical context of marine planktonic ecosystems -- Chapter 8: Seaweeds and seagrasses: the marine forests from the Alboran Sea -- Chapter 9: Benthic fauna of littoral and deep-sea habitats of the Alboran Sea: A hotspot of biodiversity -- Chapter 10: Invertebrates: the realm of diversity -- Chapter 11: Biogeographical and Macroecological context of the Alboran Sea -- Chapter 12: Biophysical processes determining the connectivity of the Alboran Sea fish populations -- Chapter 13: Evolving from fry fisheries to early life research on pelagic fish resources -- Chapter 14: Description of artisanal fisheries in northern Alboran Sea -- Chapter 15: Description of artisanal fisheries in southern Alboran Sea -- Chapter 16: Small pelagic resources: A historic perspective and current state of the resources -- Chapter 17: North Atlantic Oscillation effect on the biology and fisheries of tunas species in the Alboran Sea -- Chapter 18: Demersal Resources -- Chapter 19: The Blackspot seabream fishery in the Strait of Gibraltar: lessons and future perspectives of shared marine resource -- Chapter 20: Aquaculture in the Alboran Sea -- Chapter 21: Marine megafauna and charismatic vertebrate species -- Chapter 22: Fisheries economics and management under the impact of Human and varying marine environmental conditions in the Alboran Sea -- Chapter 23: A historical approach to living resources on the Spanish coasts from Alboran Sea between the 16th and 20th centuries -- Chapter 24: Sustainable development and Blue growth in the Alboran Sea: enabling ocean health and ecosystem services through ocean science and equitable governance -- Chapter 25: Marine Protected Areas and Key Biodiversity Areas of the Alboran Sea and adjacent areas.
    Abstract: The Alboran Sea represents a regional Mediterranean space where North and South worlds merges, creating a geopolitical region where marine resources and maritime activities should be managed from a national and international perspectives. It is widely known, that currently the planet is suffering a global change, and it is also affecting the Alboran Sea, its ecosystems and populations. An important first step to update a paramount vision on this region is to understand the climatic, geologic and oceanographic, including biochemical cycles, process which shapes the rich geodiversity, biodiversity, the productivity, and the sustainable use of the marine resources from Alboran Sea. The fisheries management system should take into account marine environmental variability to achieve biological sustainability of marine resources. Well-funded policy-makers’ decisions require a sound science based knowledge of the interaction between the marine environment and commercial stocks. This is because the role of marine environment in the evolution of fish stocks is sometimes even more important than the one played by fishers in the commercial exploitation of them. Finally, we should analyze the different aspects of political context that could affect the management of the resources from Alboran Sea in the context of climate change. This book reviews different aspects of the Alboran Sea to help understand the current situation from the original Tethis Ocean. The book is divided into four blocks: (i) Oceanographic, geological and ecological context (chapters 2 to 7), (ii) biodiversity and ecosystems distribution (chapters 8 to 12), (iii) fisheries resources and aquaculture (chapters 13 to 20), and (iv) conservation, management and marine polices (chapters 21 to 25).
    Type of Medium: Online Resource
    Pages: XVI, 939 p. 336 illus., 303 illus. in color. , online resource.
    Edition: 1st ed. 2021.
    ISBN: 9783030655167
    DDC: 577
    Language: English
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    Online Resource
    Online Resource
    Cham :Springer International Publishing :
    Keywords: Immunology. ; Stem cells. ; Medicine Research. ; Biology Research. ; Human physiology. ; Immunology. ; Stem Cell Biology. ; Biomedical Research. ; Human Physiology.
    Description / Table of Contents: Preface -- Skeletal stem cells as the developmental origin of cellular niches for hematopoietic stem and progenitor cells -- Cellular niches for hematopoietic stem cells and lympho-hematopoiesis in bone marrow during homeostasis and blood cancers -- Remodeling of the bone marrow stromal microenvironment during pathogenic infections -- The Roles of IL-7 and IL-15 in Niches for Lymphocyte Progenitors and Immune Cells in Lymphoid Organs -- Lymph node stromal cells: diverse meshwork structures weave functionally subdivided niches -- Immune Niche within the Peritoneal Cavity.
    Abstract: This volume summarizes recent advances in research on mesenchymal cell populations in the bone marrow. It explores how mesenchymal cells create niches for immune cells in extramedullary organs and it discusses new concepts of lympho-hematopoietic microenvironments. Readers are introduced to the fundamentals of hematopoietic stem cells (HSCs) differentiation to all types of blood cells, including immune cells, in the bone marrow. The book highlights how this process is supported and regulated by the individual microenvironments of stem cells, termed niches. The identity of HSC niches has been subject to longstanding debates. Recent studies identified the population of mesenchymal stem cells as the major cellular component of niches, for hematopoietic stem and progenitor cells (HSPCs) and their candidate developmental origin. Furthermore, candidate cellular niches for immune cells in lymph nodes and adipose and connective tissues were identified. The authors of this volume focus on shared features between those and HSPC niche cells in the bone marrow. Covering latest research results, this book serves as fascinating read for researchers and clinicians in hematology and immunology.
    Type of Medium: Online Resource
    Pages: VII, 134 p. 19 illus., 17 illus. in color. , online resource.
    Edition: 1st ed. 2021.
    ISBN: 9783030860165
    Series Statement: Current Topics in Microbiology and Immunology, 434
    DDC: 571.96
    Language: English
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    Online Resource
    Online Resource
    Cham :Springer International Publishing :
    Keywords: Biotic communities. ; Ecology . ; Conservation biology. ; Environmental management. ; Physical geography. ; Sustainability. ; Ecosystems. ; Ecology. ; Conservation Biology. ; Environmental Management. ; Earth System Sciences. ; Sustainability.
    Description / Table of Contents: Ecosystem Collapse and Climate Change: An Introduction -- PART I. Polar and Boreal Ecosystems -- Ecosystem Collapse on a Sub-Antarctic Island -- Permafrost Thaw in Northern Peatlands: Rapid Changes in Ecosystem and Landscape Functions -- Post-fire Recruitment Failure as a Driver of Forest to Non-forest Ecosystem Shifts in Boreal Regions -- A Paleo-perspective on Ecosystem Collapse in Boreal North America -- PART II. Temperate and Semi-arid Ecosystems -- The 2016 Tasmanian Wilderness Fires: Fire Regime Shifts and Climate Change in a Gondwanan Biogeographic Refugium -- Climate-Induced Global Forest Shifts due to Heatwave-Drought -- Extreme Events Trigger Terrestrial and Marine Ecosystem Collapses in the Southwestern USA and Southwestern Australia -- PART III. Tropical and Temperate Coastal Ecosystems -- Processes and Factors Driving Change in Mangrove Forests: An Evaluation Based on the Mass Dieback Event in Australia’s Gulf of Carpentaria -- Recurrent Mass-Bleaching and the Potential for Ecosystem Collapse on Australia’s Great Barrier Reef -- Sliding Toward the Collapse of Mediterranean Coastal Marine Rocky Ecosystems -- Marine Heatwave Drives Collapse of Kelp Forests in Western Australia -- Impact of Marine Heatwaves on Seagrass Ecosystems.
    Abstract: Human-driven greenhouse emissions are increasing the velocity of climate change and the frequency and intensity of climate extremes far above historical levels. These changes, along with other human-perturbations, are setting the conditions for more rapid and abrupt ecosystem dynamics and collapse. This book presents new evidence on the rapid emergence of ecosystem collapse in response to the progression of anthropogenic climate change dynamics that are expected to intensify as the climate continues to warm. Discussing implications for biodiversity conservation, the chapters provide examples of such dynamics globally covering polar and boreal ecosystems, temperate and semi-arid ecosystems, as well as tropical and temperate coastal ecosystems. Given its scope, the volume appeals to scientists in the fields of general ecology, terrestrial and coastal ecology, climate change impacts, and biodiversity conservation.
    Type of Medium: Online Resource
    Pages: VIII, 366 p. 93 illus., 86 illus. in color. , online resource.
    Edition: 1st ed. 2021.
    ISBN: 9783030713300
    Series Statement: Ecological Studies, Analysis and Synthesis, 241
    DDC: 577
    Language: English
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    Online Resource
    Online Resource
    Cham :Springer International Publishing :
    Keywords: Immunology. ; Cancer. ; Regenerative medicine. ; Stem cells. ; Cytology Technique. ; Immunology. ; Cancer Biology. ; Regenerative Medicine and Tissue Engineering. ; Stem Cell Biology. ; Cytological Techniques.
    Description / Table of Contents: Introduction: Rationale of using skin models in research -- Skin anatomy (human and animals for experimental research) -- In vivo skin models -- In vitro human skin models (Skin equivalents vs skin explants) -- Human skin models for studying cutaneous infections -- Skin animal models for pharmacological research -- Human skin models for pharmacological research -- Human skin models for allergological research -- Human skin models for cancer research -- Human skin models for vaccine research.
    Abstract: This edited volume discusses the application of very diverse human organotypic models in major areas of biomedical research. The authors lay a main focus on infectious diseases, cancer, allergies, as well as drug/vaccine discovery and toxicology studies. Representing a valid alternative to laboratory animals, these models are relevant for most areas of translational research. As the contemporary research shows, many human tissues can today be cultivated in vitro and used for several research objectives. This book provides an unprecedented overview of recent developments in an exciting field of research methodology. It is a reference guide for scientists in both academia and industry. Readers can update their knowledge and get hands-on recommendations on how to set up an organotypic model in their lab. Chapters 'Progress on Reconstructed Human Skin Models for Allergy Research and Identifying Contact Sensitizers' and 'Human Organotypic Models for Anti-infective Research' of this book are available open access under a CC BY 4.0 license at link.springer.com.
    Type of Medium: Online Resource
    Pages: VIII, 265 p. 22 illus., 20 illus. in color. , online resource.
    Edition: 1st ed. 2021.
    ISBN: 9783030624521
    Series Statement: Current Topics in Microbiology and Immunology, 430
    DDC: 571.96
    Language: English
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    Online Resource
    Online Resource
    Cham :Springer International Publishing :
    Keywords: Ecology . ; Ecology.
    Description / Table of Contents: Basic semiologic principles to define coherent color palettes for vegetation mapping -- Plant species distributions and ecological complexity: mapping sampling-effort bias explicitly -- Mapping of biogeographical territories: flora, vegetation and landscape criteria -- Dynamic-catenal vegetation mapping as a tool for ecologic restoration, conservation and policy -- Climate Change, Wetland Management and Alpaca Pastoralism in the Bolivian High Andes Mountains -- Essays on geobotanic mapping in the Andes of Bolivia, with particular reference to the conservation status of vegetation -- Using geobotanical tools to map and assess ecosystem services (MAES) in southern Portugal -- Spatial representation of plant diversity at geographical scale: the Italian experience -- Cognitive mapping of forest fragments -- California ultramafic vegetation: a phytosociological update -- Plant associations of the Petasition officinalis alliance in the east Carpathians (Călimani and Gurghiu Mountains) -- Arthrocaulon (Arthrocnemum) macrostachyum plant communites in the Iberian Peninsula, Balaeric and Canary Islands (Spain and Portugal) -- Geosynphytosociological typology of the French atlantic coastal rocky cliffs vegetations -- Symphytosociology: a tool for landscape monitoring: case study from the Swiss Alps -- Why does Mediterranean vegetation seem so diverse? -- Coastal dune vegetation zonation in Italy: squeezed between environmental drivers and threats -- Topographic and other constraints on evergreen broad-leaved forests in the southeastern USA -- Role of riparian zones in reducing pollution of surface and ground water, and increasing agricultural production nutrient acquisition and storage in river catchments -- Vegetation and flora of sacred natural sites in northwestern Morocco – landscape context and conservation value -- The Kaga Coast in Japan: Natural ecosystem and cultural landscape insuring biodiversity -- Species and habitat biodiversity measurement and conservation at different fine scales.
    Abstract: This book contains the papers presented at the conferences of the International Association Vegetation Science of Pirenopolis (2016) on Applied Mapping for Conservation and Management: from Plant and of Palermo (2017) on Vegetation Patterns in relation to multi-scale levels of ecological complexity: from associations to geoseries. The reports refer to general themes (semiological bases of mapping, dynamic-catenal mapping, nature conservation, plant biodiversity, biogeography, and geosynphytosociology) and their application to vegetation in different parts of the world (Andes of Bolivia, California, Kaga Coast in Japan, Southeastern USA, Morocco, Europe: Carpathians mountains, Swiss Alps, Sicily, Southern Portugal, Spain, and French Atlantic coastal). One of the benefits of the book is that it offers the possibility of comparing the different methodologies used in very different types of vegetation in the world (Boreal, Mediterranean, Tropical, Neotropical, etc.). The book is intended for researchers, Ph.D. students, and university professors.
    Type of Medium: Online Resource
    Pages: XI, 451 p. 227 illus., 141 illus. in color. , online resource.
    Edition: 1st ed. 2021.
    ISBN: 9783030749507
    Series Statement: Geobotany Studies, Basics, Methods and Case Studies,
    DDC: 577
    Language: English
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    Online Resource
    Online Resource
    Cham :Springer International Publishing :
    Keywords: Immunology. ; Medical sciences. ; Cytology. ; Biochemistry. ; Nutrition   . ; Immunology. ; Health Sciences. ; Cell Biology. ; Biochemistry. ; Nutrition.
    Description / Table of Contents: Preface -- Amino acids in intestinal physiology and health -- Amino acid metabolism in the liver: nutritional and physiological significance -- Amino acids in circulatory function and health -- Epithelial dysfunction in lung diseases: effects of amino acids and potential mechanisms -- Amino acid metabolism in the kidneys: nutritional and physiological significance -- Amino acids in health and endocrine function -- Amino Acids in Reproductive Nutrition and Health -- Impacts of amino acids on the intestinal defensive system -- Maternal nutrient restriction and skeletal muscle development: Consequences for postnatal health -- Metabolism of amino acids in the brain and their roles in regulating food intake -- Metabolism and functions of amino acids in the skin -- Metabolism and functions of amino acids in sense organs. .
    Abstract: This edited volume comprehensively highlights recent advances in the metabolism, nutrition, physiology, and pathobiology of amino acids in all the systems of humans and other animals (including livestock, poultry, companion animals, and fish). It enables readers to understand the crucial roles of amino acids and their metabolites in the health and diseases of the circulatory, digestive, endocrine, immune, muscular, nervous, reproductive, respiratory, skeletal, and urinary systems, as well as the sense organs (eyes, ears, nose, skin, and tongue). Readers will learn that amino acids are not only the building blocks of protein, but are also signalling molecules, as well as regulators of gene expression, metabolic processes and developmental changes in the body. This knowledge will guide nutritional practices to improve the growth, development and health of humans and other animals, as well as prevent and treat chronic (e.g., obesity, diabetes, and cardiovascular disorders) and infectious (e.g., bacterial, fungal, parasite, and viral) diseases. Editor of this volume is an internationally recognized expert in nutritional biochemistry. He has over 38 years of experience with research and teaching at world-class universities in the area of amino acid biochemistry, nutrition, and physiology. He has published more than 625 papers in peer-reviewed journals, 62 chapters in books, and authored two text/reference books, with an H-index of 117 and more than 55,000 citations in Google Scholar. This publication is a useful reference for professionals as well as undergraduate and graduate students in animal science, biochemistry, biomedical engineering, biology, human medicine, food science, kinesiology, nursing, nutrition, pharmacology, physiology, toxicology, veterinary medicine, and other related disciplines. In addition, all chapters provide general and specific references to amino acids in systems health for researchers and practitioners in biomedicine, animal and plant agriculture, and aquaculture, and for government policy makers.
    Type of Medium: Online Resource
    Pages: VI, 220 p. 36 illus., 10 illus. in color. , online resource.
    Edition: 1st ed. 2020.
    ISBN: 9783030453282
    Series Statement: Advances in Experimental Medicine and Biology, 1265
    DDC: 571.96
    Language: English
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    Online Resource
    Online Resource
    Cham :Springer International Publishing :
    Keywords: Immunology. ; Pharmacology. ; Diseases. ; Cancer. ; Immunology. ; Pharmacology. ; Diseases. ; Cancer Biology.
    Description / Table of Contents: 1. Human Chronic Viruses: Pathogenesis, host response, and treatment -- 2. Defining the Role of Immunoproteomics in Human Immunotherapy -- 3. Microbiome and Cellular Players in Type 1 Diabetes: from Pathogenesis to Protection -- 4. Immune Mechanisms, Pathology, and Management of Allergic Ocular Diseases -- 5. Dendritic Cell-regulated T Cell Immunity and Tolerance against Acute Myeloid Leukemia -- 6. Perspectives on the Role of T cell Negative Immune Checkpoint Receptors in Health and Disease -- 7. Neuroprotective Immunity for Neurodegenerative and Neuroinfectious Diseases -- 8. Polycystic Ovary Syndrome: An overview of a complex, heterogeneous genetic condition.
    Abstract: This book highlights information derived primarily from clinical samples, with particular reference to theoretical and scientific aspects of the human immune system. This text will focus on topics that range from host-pathogen interactions in infectious disease to host immune response in cancer, allergic diseases, neuroinflammatory diseases, and autoimmune disorders. The reader will also have a well-rounded understanding of the behavior of the immune system with particular emphasis on the role of immunoproteomics in immunotherapy, neuroprotective immunity for neurodegenerative and neuroinfectious disease, leukemia-associated dendritic cell induction of adaptive immunity dysregulation, and the role of immune checkpoint inhibitors in cancer, infection, as well as neuroinflammation. Taken together, the contents of this book are intended for both clinicians and researchers in academia and industry.
    Type of Medium: Online Resource
    Pages: XVIII, 403 p. 16 illus., 5 illus. in color. , online resource.
    Edition: 1st ed. 2020.
    ISBN: 9783030339463
    DDC: 571.96
    Language: English
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    Online Resource
    Online Resource
    Cham :Springer International Publishing :
    Keywords: Immunology. ; Life sciences. ; Pharmacology. ; Medical sciences. ; Medicine History. ; Public health. ; Immunology. ; Life Sciences. ; Pharmacology. ; Health Sciences. ; History of Medicine. ; Public Health.
    Description / Table of Contents: 1. Introduction -- 2. From Africa to England -- 3. The children's clinic at Keyworth -- 4. Whooping cough vaccine -- 5. 1977-79: The first outbreak of whooping cough -- 6. Does the vaccine work? -- 7. 1981: Whooping cough vaccine is very rarely harmful -- 8. 1981-83: The second outbreak. How many cases are there really? -- 9.1985-87: The third outbreak. The search for subclinical infection -- 10. Does the effectiveness of the vaccine wear off? -- 11. 1988: Trying to raise the uptake of pertussis vaccine -- 12. 1989-91: The fourth outbreak. The natural history of whooping cough -- 13. 1990's: Whooping cough fades away but new diagnostic tests emerge -- 14. 2000: Whoopingcough.net. Overcoming diagnostic paralysis -- 15. The early noughties: The new tests aid the rediscovery of whooping cough -- 16. Late noughties: "Resurgence" of whooping cough in the USA and Australia puts the UK on alert -- 17. 2012: Whooping cough diagnoses peak in the UK but remain unchanged in Keyworth -- 18. What lies ahead? -- 19. Epilogue -- Appendix.
    Abstract: Outbreak in the Village is a fascinating account of the personal and professional journey of Dr. Doug Jenkinson, physician and researcher. Over the course of four decades in practice, Jenkinson traces the reemergence of whooping cough in the developed world, using his practice in the idyllic English countryside as a clinical control group. Keeping meticulous notes and indulging an itch to investigate, he explores one of history's most enigmatic and pervasive diseases. Jenkinson relates the tale of his life's work amid winsome anecdotes, relevant history, and practical advice. Told in an amiable, engaging voice with an expert balance of levity and earnestness, this story will charm casual readers interested in medical history and memoir, as well as doctors and researchers who identify with the experiences and may benefit from the research and techniques employed. Readers will find themselves in the examination room beside Jenkinson as the investigation unfolds, learning about the nature of the illness and the sweeping detrimental effects of an anti-vaccination campaign. An intriguing memoir about a mysterious illness, a public health failure, and one doctor's quest for clarity, Outbreak in the Village is a tale of perseverance and objectivity sure to delight and inform. .
    Type of Medium: Online Resource
    Pages: XXIII, 158 p. 63 illus., 43 illus. in color. , online resource.
    Edition: 1st ed. 2020.
    ISBN: 9783030454852
    Series Statement: Springer Biographies,
    DDC: 571.96
    Language: English
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    Keywords: Biotic communities. ; Biodiversity. ; Freshwater ecology. ; Marine ecology. ; Climatology. ; Physical geography. ; Botanical chemistry. ; Ecosystems. ; Biodiversity. ; Freshwater and Marine Ecology. ; Climate Sciences. ; Physical Geography. ; Plant Biochemistry.
    Description / Table of Contents: Preface -- The marine physical environment during the Polar Night -- Light in the Polar Night -- Marine micro- and macroalgae in the Polar Night -- Zooplankton in the Polar Night -- Benthic communities in the Polar Night -- Fish ecology in the Polar Night -- Biological clocks and rhythms in polar organisms -- Sensor carrying platforms -- Operative habitat mapping and monitoring in the Polar Night -- The Polar Night exhibition: Life and light at the dead of night -- Index.
    Abstract: Until recently, the prevailing view of marine life at high latitudes has been that organisms enter a general resting state during the dark Polar Night and that the system only awakens with the return of the sun. Recent research, however, with coordinated, multidisciplinary field campaigns based on the high Arctic Archipelago of Svalbard, have provided a radical new perspective. Instead of a system in dormancy, a new perspective of a system in full operation and with high levels of activity across all major phyla is emerging. Examples of such activities and processes include: Active marine organisms at sea surface, water column and the sea-floor. At surface we find active foraging in seabirds and fish, in the water column we find a high biodiversity and activity of zooplankton and larvae such as active light induced synchronized diurnal vertical migration, and at seafloor there is a high biodiversity in benthic animals and macroalgae. The Polar Night is a period for reproduction in many benthic and pelagic taxa, mass occurrence of ghost shrimps (Caprellides), high abundance of Ctenophores, physiological evidence of micro- and macroalgal cells that are ready to utilize the first rays of light when they appear, deep water fishes found at water surface in the Polar night, and continuous growth of bivalves throughout the winter. These findings not only begin to shape a new paradigm for marine winter ecology in the high Arctic, but also provide conclusive evidence for a top-down controlled system in which primary production levels are close to zero. In an era of environmental change that is accelerated at high latitudes, we believe that this new insight is likely to strongly impact how the scientific community views the high latitude marine ecosystem. Despite the overwhelming darkness, the main environmental variable affecting marine organisms in the Polar Night is in fact light. The light regime during the Polar Night is unique with respect to light intensity, spectral composition of light and photoperiod. .
    Type of Medium: Online Resource
    Pages: XI, 375 p. 133 illus., 116 illus. in color. , online resource.
    Edition: 1st ed. 2020.
    ISBN: 9783030332082
    Series Statement: Advances in Polar Ecology, 4
    DDC: 577
    Language: English
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    Online Resource
    Online Resource
    Cham :Springer International Publishing :
    Keywords: Immunology. ; Cytology. ; Molecular genetics. ; Stress (Physiology). ; Immunology. ; Cell Biology. ; Molecular Genetics. ; Cellular Stress.
    Description / Table of Contents: Chapter 1. Molecular mechanisms of Nrf2 in inflammation: Interactions between Nrf2 and inflammatory mediators -- Chapter 2. Nrf2 in immune responses during inflammation -- Chapter 3. Nrf2 and Nrf2-interacting network in respiratory inflammation and diseases -- Chapter 4. Nrf2 in the regulation of endothelial cell homeostasis during inflammation -- Chapter 5. The roles of Nrf2 in cardiovascular system and atherosclerosis -- Chapter 6. Nrf2 and inflammation-triggered carcinogenesis -- Chapter 7. Role of Nrf2 in oxidative and inflammatory processes in obesity and metabolic diseases -- Chapter 8. Modulators of Nrf2 Activation during Inflammation.
    Abstract: Nrf2, a transcription factor that mediates transcriptional responses to oxidative and xenobiotic stresses, plays a central role in cellular protection against internal or external toxins. Defects in Nrf2 and the relevant regulatory pathways are associated with a number of pathologies including inflammation,respiratory diseases, cardiovascular dysfunctions, metabolic syndrome and diabetes, neurodegeneration, and cancer. This book comprehensively reviews the up-to-date discoveries for the roles of Nrf2 in several human diseases in the context of inflammation. In particular, the molecular mechanisms that mediate the functions of Nrf2 and its interacting network in inflammation and pathogenesis are explicated. In addition, the research and therapeutic applications of Nrf2-targeting compounds in different diseases were summarized. This book is expected to be a valuable reference for worldwide researchers conducting both mechanistic and therapeutic studies of Nrf2 and relevant factors.
    Type of Medium: Online Resource
    Pages: IX, 205 p. 51 illus., 12 illus. in color. , online resource.
    Edition: 1st ed. 2020.
    ISBN: 9783030445997
    Series Statement: Progress in Inflammation Research, 85
    DDC: 571.96
    Language: English
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  • 77
    Keywords: Ecology . ; Environment. ; Biotic communities. ; Ecology. ; Environmental Sciences. ; Ecosystems.
    Description / Table of Contents: Chapter 1: Introduction: Ecological Subsidies as a Framework for Understanding Contaminant Fate, Exposure, and Effects at the Land-Water Interface -- Part I: Ecological Subsidies Drive Exposure -- Chapter 2: Ecological Factors Controlling Insect-Mediated Methylmercury Flux from Aquatic to Terrestrial Ecosystems: Lessons Learned from Mesocosm and Pond Experiments -- Chapter 3: Pathways of Contaminant Transport Across the Aquatic-Terrestrial Interface: Implications for Terrestrial Consumers, Ecosystems and Management -- Part II: Exposure Drives Ecological Subsidies -- Chapter 4: Agriculture and Mining Contamination Contribute to a Productivity Gradient Driving Cross-Ecosystem Associations between Stream Insects and Riparian Arachnids -- Chapter 5: Cross-Ecosystem Linkages and Trace Metals at the Land-Water Interface -- Chapter 6: Metamorphosis and the Impact of Contaminants on Ecological Subsidies -- Part III: Other Global Stressors -- Chapter 7: Variables Affecting Resource Subsidies from Streams and Rivers to Land and their Susceptibility to Global Change Stressors -- Chapter 8: Beyond “Donors and Recipients”: Impacts of Species Gains and Losses Reverberate among Ecosystems due to Changes in Resource Subsidies -- Part IV: Management Applications and Tools -- Chapter 9: Practical Considerations for the Incorporation of Insect-Mediated Contaminant Flux into Ecological Risk Assessments -- Chapter 10: When Nutrients Become Contaminants in Aquatic Systems: Identifying Responses to Guide Terrestrial-Derived Detrital Endpoint Development for Managers -- Chapter 11: Mesocosms to Evaluate Aquatic-Terrestrial Contaminant Linkages using Aquatic Insect Emergence: Utility for Aquatic Life Criteria Development -- Chapter 12: Studying Effects of Contaminants on Aquatic-Terrestrial Subsidies: Experimental Designs using Outdoor and Indoor Mesocosms and Microcosms -- Part V: Syntheses -- Chapter 13: Ecological Networks as a Framework for Understanding and Predicting Contaminant Movement across the Land-Water Interface -- Chapter: 14: Synthesis: A Framework for Predicting the Dark Side of Ecological Subsidies.
    Abstract: This volume explores the effects of aquatic contaminants on ecological subsidies and food web exposure at the boundary of aquatic and terrestrial ecosystems. It provides the first synthesis of the findings and principles governing the “dark side” of contaminant effects on ecological subsidies. Furthermore, the volume provides extensive coverage of the tools being developed to help managers and researchers better understand the implications of contaminants movement and their effects on natural resources and ecosystem processes. Aquatic and terrestrial ecosystems are linked through movements of energy and nutrients which subsidize recipient food webs. As a result, contaminants that concentrate in aquatic systems because of the effects of gravity on water and organic matter have the potential to impact both aquatic and terrestrial ecosystem processes. Within the last decade, increased attention has been paid to this phenomenon, particularly the effects of aquatic contaminants on resource and contaminant export to terrestrial consumers, and the potential implications for management. This volume, curated and edited by three field leaders, incorporates empirical results, management applications and theoretical synthesis and is a key reference for academics, government researchers and consultants.
    Type of Medium: Online Resource
    Pages: XV, 383 p. , online resource.
    Edition: 1st ed. 2020.
    ISBN: 9783030494803
    DDC: 577
    Language: English
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  • 78
    Keywords: Ecology . ; Biotic communities. ; Pollution. ; Water. ; Hydrology. ; Ecology. ; Ecosystems. ; Pollution. ; Water.
    Abstract: This book is the final installation in a three-volume series synthesizing 30 years of mercury research in the Florida Everglades. The first part of this book evaluates the occurrence of trends in both biota mercury concentrations and atmospheric mercury deposition. Through both empirical and deterministic analyses, the likely drivers of biota trends are identified. These analyses help lay the predicate for devising an overall strategy to mitigate and manage the Everglades mercury problem. The book concludes with a model analysis of the likely benefits and uncertainty attendant with implementing the leading candidate strategy for best reducing the Everglades mercury problem.
    Type of Medium: Online Resource
    Pages: XV, 164 p. 78 illus., 72 illus. in color. , online resource.
    Edition: 1st ed. 2020.
    ISBN: 9783030556358
    DDC: 577
    Language: English
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  • 79
    Online Resource
    Online Resource
    Cham :Springer International Publishing :
    Keywords: Ecology . ; Zoology. ; Conservation biology. ; Ecology. ; Zoology. ; Conservation Biology.
    Description / Table of Contents: 1. Introduction: aquatic insects in Australia’s environments -- 1.1. The background to concern -- References -- 2. Major habitats -- 2.1. Introduction -- 2.2. Ponds and lakes -- 2.3. Streams and rivers -- References -- 3. Australian inland waters -- 3.1. Introduction -- 3.2. Waterfalls -- 3.3. Subterranean aquifers -- 3.4. Rock pools -- 3.5. Mound springs -- 3.6. Lakes -- 3.7. Billabongs -- 3.8. Streams and rivers -- 3.9. Exposed riverine sediments -- References -- 4. Monitoring freshwater macroinvertebrates -- 4.1. Scope and needs for assessments -- References -- 5. Threats: the background variations in condition -- 5.1. Introduction -- 5.2. Drought -- 5.3. Flood -- References -- 6. Major imposed threats -- 6.1. Introduction -- 6.2. Water temperature -- 6.3. Sedimentation -- 6.3.1. Mining -- 6.4. Pollution -- 6.5. Salinisation -- 6.6. Exploitation -- 6.7. Electrofishing -- 6.8. Changes to riparian vegetation -- 6.8.1. Emergent vegetation -- 6.9. Alien species -- 6.9.1. Plants -- 6.9.2. Fish -- 6.9.3. Mammals -- 6.10. River regulation -- 6.11. Fire -- 6.12. Urbanisation -- 6.13. Recreation -- 6.14. Ecological traps -- 6.15. Climate change -- References -- 7. Macroinvertebrates of inland waters -- 7.1. Introduction -- 7.2. The variety of aquatic insects -- 7.3. Other macroinvertebrates -- 7.3.1. Crustaceans -- 7.3.2. Molluscs -- References -- 8. Insects of Australia’s inland waters -- 8.1. Introduction -- 8.2. Ephemeroptera -- 8.3. Odonata -- 8.4. Plecoptera -- 8.5. Hemiptera -- 8.6. Coleoptera -- 8.7. Mecoptera -- 8.8. Megaloptera -- 8.9. Neuroptera -- 8.10. Lepidoptera -- 8.11. Trichoptera -- 8.12. Diptera -- 8.12.1. Control of aquatic pest flies -- References -- 9. Australia’s flagship freshwater insects -- 9.1. Introduction -- 9.2. Selected flagship taxa -- References -- 10. Ecology and management -- 10.1. Introduction -- 10.2. Dispersal -- 10.2.1. Impacts of urban lighting -- 10.2.2. Pond colonization -- References -- 11. Conservation -- 11.1. Introduction -- 11.2. Protected areas -- 11.3. Management and restoration -- 11.4. Fish conservation -- 11.5. Education and involvement -- 11.6. Artificial water bodies -- 11.7. Temporary ponds -- 11.8. Intermittent streams -- 11.9. Stormwater retention ponds -- 11.10. Refuges -- 11.11. Woody debris -- 11.12. Riparian zones -- 11.13. Perspective and prospects -- References -- Appendix 1 -- Index.
    Abstract: The inland waters of Australia, and their largely endemic insect inhabitants, are subject to a wide and increasing variety of threats that continue to change those environments and lead to losses of insect habitats and localised taxa. Many of those changes result from human needs for water and measures to assure supply in naturally varied flood/drought regimes on which anthropogenic changes are imposed, and to which aquatic biota are increasingly susceptible. This book is a broad overview of Australian aquatic insects, the problems they face as changes to key habitats occur, and measures by which their survival may be enhanced through practical conservation. As well as summarising the current conservation interest in aquatic insects in Australia, the text draws on information and case histories from many parts of the world to augment the generally more limited information from Australian taxa and their needs, to facilitate use and perspective on conservation practice by non-specialist conservation managers, whilst also being of value to entomologists interested more directly in aquatic insect ecology and conservation .The numerous references to many taxa, regions and ecological contexts provide examples for possible emulation in Australia, and summarises many practical lessons relevant to honing effective conservation across the range from individual threatened species to the more complex protection or restoration of aquatic communities in which insects play significant functional roles.
    Type of Medium: Online Resource
    Pages: XIV, 303 p. 45 illus. , online resource.
    Edition: 1st ed. 2020.
    ISBN: 9783030570088
    DDC: 577
    Language: English
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  • 80
    Online Resource
    Online Resource
    Cham :Springer International Publishing :
    Keywords: Biotic communities. ; Biogeography. ; Physical geography. ; Environmental policy. ; Landscape ecology. ; Biodiversity. ; Ecosystems. ; Biogeosciences. ; Physical Geography. ; Environmental Policy. ; Landscape Ecology. ; Biodiversity.
    Description / Table of Contents: Part I: Ecosystem Services Basics -- Chapter 1. Overview of the ecosystem services concept -- Part II: Ecosystem Services of Slovakia -- Chapter 2. Methodology of national ES assessment -- Chapter 3. Provisioning ecosystems services -- Chapter 4. Regulatory ecosystem services and supporting ecosystem functions -- Chapter 5. Cultural ecosystems services -- Part III: Synthesis -- Chapter 6. Synthesis of ecosystem services assessment in Slovakia.
    Abstract: This book provides the first comprehensive assessment of ecosystem services (ES) for the territory of the Slovak Republic. Although the ES approach is widely used for the evaluation of the benefits of natural capital and biodiversity for people, this book has a unique character. It provides an assessment of 18 individual ES, which are divided into three main groups - provisioning, regulatory/supporting and cultural ES. For each of ES, a brief theoretical and methodological overview is given, followed by spatial assessment based on own original methodology and dataset of 40 map layers. Besides, an evaluation of main ES groups and overall ES assessment is realized. This book emphasizes the key role of nature protection areas, large areas of forest ecosystems and mountain and sub-mountain areas, for the preservation of the various functions of the healthy landscape and ecosystems. The complexity of the book guarantees its usefulness - not only as the knowledge base for the territory of Slovakia but also as the methodological tool for worldwide researchers.
    Type of Medium: Online Resource
    Pages: XXVI, 244 p. 114 illus., 110 illus. in color. , online resource.
    Edition: 1st ed. 2020.
    ISBN: 9783030465087
    DDC: 577
    Language: English
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  • 81
    Online Resource
    Online Resource
    Cham :Springer International Publishing :
    Keywords: Immunology. ; Diseases. ; Cancer. ; Human physiology. ; Immunology. ; Diseases. ; Cancer Biology. ; Human Physiology.
    Description / Table of Contents: Basics of Inducible Lymphoid Organs -- Role of iBALT in respiratory immunity -- Chronic inflammation in mucosal tissues: Barrier integrity, inducible lymphoid tissues, and immune surveillance -- Role of lymphoid structure in skin immunity -- Memory lymphocyte clusters in genital immunity: Role of tissue-resident memory T cells (TRM) -- Ectopic lymphoid tissue in Rheumatoid Arthritis -- Artificial construction of immune tissues/organoids and their application for immunological intervention.
    Abstract: This book sheds new light on “inducible” lymphoid organs (ILOs): antigen presentation sites that are generated de novo in peripheral tissues under various pathogenic conditions. Accomplished immunologists demonstrate that the physiological role of these ILOs is completely different from that of central lymphoid organs, i.e., the lymph nodes or spleen. In addition to the central organs, the ILOs are considered essential structures for the efficient elicitation of adaptive immune responses in lesions. The respective chapters highlight examples from multiple sites, e.g. the skin, lung, intestinal tract, genital tract, the synovial membrane of the joints and artificial lymph nodes. Accordingly, readers will learn that ILO structure and function can vary substantially, depending on the context. Presenting the results of the latest immunological research, the book offers a fascinating and insightful read for both scientists and clinicians in the areas of infectious and immune-associated diseases.
    Type of Medium: Online Resource
    Pages: VII, 160 p. 1 illus. , online resource.
    Edition: 1st ed. 2020.
    ISBN: 9783030517472
    Series Statement: Current Topics in Microbiology and Immunology, 426
    DDC: 571.96
    Language: English
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  • 82
    Keywords: Immunology. ; Immunology.
    Description / Table of Contents: 1. Core Concepts in Immunology: The Definition of Autoimmunity and Its Unique Application to the Seat of Tolerance, the Liver -- 2. The Liver as a Lymphoid Organ -- 3. The Uniqueness of Innate Immunity -- 4. Adaptive Immunity and the Clinical Definition of Autoantibodies.-5. Genetics of Autoimmune Liver Diseases -- 6. The Epigenetic Basis of Loss of Tolerance -- 7. Bile Acids and Bilirubin in Liver Immunology -- 8. The Microbiota-Gut-Liver Axis – Implications for the Pathophysiology of Liver Disease -- 9. Diagnostic Liver Immunology -- 10. The Pathologist’s Approach to Reviewing Liver Histology -- 11. Geoepidemiology of Autoimmune Liver Diseases -- 12. Immune Responses to Bacterial Infections -- 13. Immunity of Parasitic Infections of the Liver -- 14. The Treatment of Bacterial and Parasitic Diseases of the Liver -- 15. Hepatitis A and Other Viral Infections -- 16. Hepatitis B Virus -- 17. Hepatitis C -- 18. Hepatitis D -- 19. Hepatitis E -- 20. Alcohol-Associated Liver Disease -- 21. Non-alcoholic Fatty Liver Disease: A Chapter in Liver Immunology -- 22. Primary Biliary Cholangitis -- 23. PSC – AIH Overlap -- 24. Primary Biliary Cholangitis: Autoimmune Hepatitis Overlap Syndrome -- 25. Primary Sclerosing Cholangitis -- 26. Autoimmune Hepatitis -- 27. IgG4-related Disease: Current Concept, Diagnosis, and Pathogenesis -- 28. Pediatric Liver Disease -- 29. Mechanisms of Acute Liver Failure -- 30. Immune-Mediated Drug-Induced Liver Injury -- 31. Hepatobiliary Cancers and Immunology -- 32. Acute-on-Chronic Liver Failure -- 33. The Pathogenesis of Liver Diseases in Pregnancy -- 34. Graft-Versus-Host Disease -- 35. Immunopathogenesis of Liver Cirrhosis -- 36. Immune-Mediated Liver Disease in the Transplanted Liver.
    Abstract: The third edition of this acclaimed work provides clinicians and investigators with a wealth of state-of-the-art information that will lead to fresh approaches in thinking about liver physiology and liver diseases. Developed by a panel of renowned international authors, this edition outlines a range of important advances in our understanding of the liver’s role as an immune organ and the functions of innate and adaptive immunity in the pathogenesis of all liver diseases. Indeed, the liver is a vitally important immune organ producing liver-derived products that can trigger the innate and adaptive immune system to initiate, mediate, regulate, and resolve systemic inflammation. The book begins with an analysis of the core concepts of immunology, including the definition of autoimmunity and its unique application to the liver, a tolerogenic organ. Subsequent chapters then explore the biological elements of liver diseases caused by epigenetics, genetics, and innate and adaptive immunity. Specific clinical presentations and aspects of liver diseases are also examined, such as Hepatitis C, non-alcoholic fatty liver disease and parasitic infections. Closing chapters then discuss liver diseases among specific populations, including pediatrics, those with comorbidities and preexisting conditions, pregnant women, and finally patients with transplanted organs. A timely and invaluable update to the clinical literature, Liver Immunology: Principles and Practice, Third Edition, is once again a comprehensive work that will not only enhance the understanding of liver diseases but also provide the kind of novel insights that greatly accelerates the evidence-based care of children and adults afflicted with these diseases. This volume is again a must-read for clinicians at all levels, for investigators and for students. .
    Type of Medium: Online Resource
    Pages: XV, 633 p. 145 illus., 135 illus. in color. , online resource.
    Edition: 3rd ed. 2020.
    ISBN: 9783030517090
    DDC: 571.96
    Language: English
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  • 83
    Keywords: Biotic communities. ; Oceanography. ; Physical geography. ; Water. ; Hydrology. ; Environment. ; Ecosystems. ; Ocean Sciences. ; Earth System Sciences. ; Water. ; Environmental Sciences.
    Description / Table of Contents: Part I: Introductory Communications -- Chapter 1. Our Future and The Oceans -- Chapter 2. General guidelines for future exchanges in marine science and technology between the two Sociétés franco-japonaises d’Océanographie -- Part II: Identification and Analysis of Environmental Stressors -- Chapter 3. The Japan Sea: a changing Pacific Asian marginal sea -- Chapter 4. Statistical analysis of surface circulation in Sagami Bay using High Frequency(HF)Radar -- Chapter 5. Statistical analysis of high frequency pCO2 data acquired with the Astan buoy (Southern Western English Channel, off Roscoff) -- Chapter 6. Spatial variation in pCO2 based on 16 years of in-situ measurements in the Seto Inland Sea, Japan -- Chapter 7. The Bay of Seine: a resilient socio-eco-system under cumulative pressures -- Chapter 8. Effect of bacterial infection on the expression of stress proteins and antioxidative enzymes in Japanese flounder -- Part III: Impacts on Socio-Eco-Systems and Biological Resources -- Chapter 9. A Review of the Effects of Global Warming and Currents Trends on Fisheries and its Impact on Important Commercial Species in Japan -- Chapter 10. Physiology of winter coral bleaching in temperate zone -- Chapter 11. Preliminary report of impacts of the 2011 earthquake and tsunami and subsequent events on macrobenthic community in a shallow brackish lagoon in Sendai Bay, Japan -- Chapter 12. Post-tsunami oyster feeding environment in Nagatsuraura Bay for three years -- Chapter 13. Seagrass-oyster farmers interaction detected by eelgrass DNA analysis in Hinase area of the Seto Inland Sea, Japan -- Chapter 14. Fisheries Biology of Blue Sharks in Sagami Bay, Japan -- Part IV: Vulnerability of Coastal Ecosystems and Risk Assessment -- Chapter 15. Temperature and salinity changes in coastal waters of Western Europe: variability, trends and extreme events -- Chapter 16. Risk Based Consenting of Offshore Renewable Energy Projects (RICORE) -- Chapter 17. Does global warming favour the occurrence of recent blue mussel mortality events in France? -- Chapter 18. Integrated ecosystem management for exploited coastal ecosystem dynamics under oligotrophication and climate changes -- Chapter 19. Forty years of decline and 10 years of management plan: are European eels (Anguilla anguilla) recovering? -- Chapter 20. The management of Mediterranean coastal habitats: a plea for a socio-ecosystem-based approach.
    Abstract: Coastal and estuarine environments at the interface of terrestrial and marine areas are among the most productive in the world. However, since the beginning of the industrial era, these ecosystems have been subjected to strong anthropogenic pressures intensified from the second half of the 20th century, when there was a marked acceleration in the warming (climate change) of the continents, particularly at high latitudes. Coastal ecosystems are highly vulnerable to alteration of their physical, chemical and biological characteristics (marine intrusion, acidification of marine environments, changes in ecosystems, evolution and artificialization of the coastline, etc.). In contact with heavily populated areas, these environments are often the receptacle of a lot of chemical and biological pollution sources that significantly diminish their resilience. In this context of accelerated evolution and degradation of these areas important for food security of many populations around the world, it is necessary to better identify the factors of pressure and understand, at different scales of observation, their effects and impacts on the biodiversity and on the socio-eco-systems, in order to determine the degree of vulnerability of these coastal ecosystems and the risks they face. A transdisciplinary and integrated approach is required to prevent risks. Within this framework, operational coastal oceanography occupies an important place but also the implementation of a true socio-eco-system approach in order to set up an environmentally friendly development.
    Type of Medium: Online Resource
    Pages: XXIX, 517 p. 248 illus., 194 illus. in color. , online resource.
    Edition: 1st ed. 2020.
    ISBN: 9783030434847
    DDC: 577
    Language: English
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  • 84
    Online Resource
    Online Resource
    Cham :Springer International Publishing :
    Keywords: Biotic communities. ; Environment. ; Ecology . ; Ecosystems. ; Environmental Sciences. ; Terrestial Ecology.
    Description / Table of Contents: Chapter1.Introduction: What Persists, what Changes -- Chapter2.The mountains -- Chapter3.It's getting warm down here -- Chapter4.Water towers of the west -- Chapter5.Trees, forests, and carbon -- Chapter6.Ecological disturbance -- Chapter7.Creatures great and small -- Chapter8.Extremes, Thresholds, Vulnerabilities -- Chapter9.Mountains and People in a Warming World.
    Abstract: This book is written for general readers with an interest in science, and offers the tools and ideas for understanding how climate change will affect mountains of the American West. A major goal of the book is to provide material that will not become quickly outdated, and it does so by conveying its topics through constants in ecological science that will remain unchanged and scientifically sound. The book is timely in its potential to be a long-term contribution, and is designed to inform the public about climate change in mountains accessibly and intelligibly. The major themes of the book include: 1) mountains of the American West as natural experiments that can distinguish the effects of climate change because they have been relatively free from human-caused changes, 2) mountains as regions with unique sensitivities that may change more rapidly than the Earth as a whole and foreshadow the nature and magnitude of change elsewhere, and 3) different interacting components of ecosystems in the face of a changing climate, including forest growth and mortality, ecological disturbance, and mountain hydrology. Readers will learn how these changes and interactions in mountains illuminate the complexity of ecological changes in other contexts around the world.
    Type of Medium: Online Resource
    Pages: XV, 235 p. 53 illus., 49 illus. in color. , online resource.
    Edition: 1st ed. 2020.
    ISBN: 9783030424329
    DDC: 577
    Language: English
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  • 85
    Keywords: Ecology . ; Pollution. ; Environment. ; Water. ; Hydrology. ; Biophysics. ; Arts. ; Ecology. ; Pollution. ; Environmental Sciences. ; Water. ; Biophysics. ; Arts.
    Description / Table of Contents: Chapter 1. The Exhibition MARE PLASTICUM: Art and Science for the Environment -- Chapter 2. A Brief History of Plastics -- Chapter 3. Plastics and Microplastics: Impacts in the Marine Environment -- Chapter 4. The (Un)Natural History of the “Plastisphere”, A New Marine Ecosystem -- Chapter 5. Polarquest 2018 Expedition: Plastic Debris at 82°07’ North -- Chapter 6. The Impact of Marine Litter in Marine Protected Areas (MPAs) in the Mediterranean Sea: How Can We Protect MPAs? -- Chapter 7. Plastic in China: A Short History of a Crisis -- Chapter 8. "Down by the River": (Micro-) Plastic Pollution of Running Freshwaters with Special Emphasis on the Austrian Danube -- Chapter 9. Small Plastic Wastes in Soils: What Is Our Real Perception of the Problem? -- Chapter 10. Europe's Move Towards Plastic-Free Ocean -- Chapter 11. Plastic Pollution in the Oceans - A Systemic Analysis—Status Quo and Possible Sustainable Solutions -- Chapter 12. Toys for the Winter -- Chapter 13. "The Bottlenose Dolphin” (An Eco-comic).
    Abstract: This book, written by a multidisciplinary team of authors comprising scientists, artists and communicators, explores one of the most pressing issues of our time – the menace plastics pose to marine environments and organisms. It takes readers on a journey that begins on the beaches of Galicia, where the beach litter formed the starting point for an exhibition that combines art and science to alert the audience to the urgent need for action. The journey culminates with a short “plastic story”, which reveals a disturbing vision of the future significance of plastics for humans, and an example of how comics can deliver information to a younger audience. Along the way there is plenty of fascinating science, such as insights into the impacts of plastics and microplastics; the new marine ecosystem, known as the “plastisphere”; and the current status of the oceans, from the Arctic to the Mediterranean. The book also explores the historical developments; sustainable solutions, including the use of circular economy methodologies; and protective measures, like those being tried in China and the Far East. Lastly, it describes the role played by rivers as transport vectors for plastic, with special reference to the Danube, and to complete the picture, since most of the plastic is of terrestrial origin, it investigates problems related to microplastics in soils.
    Type of Medium: Online Resource
    Pages: XV, 252 p. 89 illus., 75 illus. in color. , online resource.
    Edition: 1st ed. 2020.
    ISBN: 9783030389451
    DDC: 577
    Language: English
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  • 86
    Keywords: Biotic communities. ; Microbial ecology. ; Freshwater ecology. ; Marine ecology. ; Biogeography. ; Biodiversity. ; Biology Technique. ; Ecosystems. ; Microbial Ecology. ; Freshwater and Marine Ecology. ; Biogeosciences. ; Biodiversity. ; Biological Techniques.
    Description / Table of Contents: Part 1. Litter dynamics: chapter 1. Litter Input (Arturo Elosegi & Jesús Pozo) -- Chapter 2. Leaf Retention (Arturo Elosegi) -- chapter 3. Manipulating Litter Retention in Streams (Michael Dobson) -- chapter 4. Coarse Benthic Organic Matter (Jesús Pozo & Arturo Elosegi) -- chapter5. Leaching (Felix Bärlocher) -- Chapter 6. Leaf Mass Loss Estimated by the Litter-Bag Technique (Felix Bärlocher) -- Chapter7. Determining Litter Mass Loss by the Plant Tagging Approach (Kevin A. Kuehn & Mark O. Gessner) -- Chapter 8. Wood Decomposition (Arturo Elosegi, Maite Arroita & Libe Solagaistua) -- Chapter9. Decomposition of Fine Particulate Organic Matter (Yoshimura Chihiro) -- Chapter10. Coarse Particulate Organic Matter Budgets (Jesús Pozo & Jon Molinero) -- Part 2. Chemical and Physical Leaf Properties. Chapter11. Total Phosphorus, Nitrogen, and Carbon in Leaf Litter (Mogens R. Flindt, Ana I. Lillebø, Javier Pérez & Verónica Ferreira) -- Chapter12. Total Protein (Mark O. Baerlocher) -- Chapter13. Free Amino Acids (Shawn D. Mansfield & Mark O. Baerlocher) -- chapter14. Determination of Total Carbohydrates (Shawn D. Mansfield) -- chapter15. Determination of Soluble Carbohydrates (Letitia da Ros, Faride Unda, Shawn D. Mansfield) -- Chapter16. Total Lipids (Mark O. Gessner & Paul T. M. Neumann) -- Chapter17. Polyunsaturated Fatty Acids in Decomposing Leaf Litter (Eric Von Elert) -- Chapter18. Total Phenolics (Felix Bärlocher & Manuel A.S. Graça) -- Chapter19. Radial Diffusion Assay for Tannins (Manuel A.S. Graça & Felix Bärlocher) -- Chapter20. Acid Butanol Assay to Determine Bulk Concentrations of Condensed Tannins (Mark O. Gessner & Daniel Steiner) -- Chapter21. Lignin and Cellulose (Mark O. Gessner) -- Chapter22. Physical Litter Properties: Leaf Toughness and Tensile Strength (Manuel A.S. Graça & Martin Zimmer) -- Part 3. Microbial Decomposers. Chapter23. Techniques for Handling Ingoldian Fungi (Enrique Descals) -- Chapter24. Maintenance of Aquatic Hyphomycete Cultures (Ludmila Marvanová) -- Chapter 25. An Illustrated Key to the Common Temperate Species of Aquatic Hyphomycetes (Vladislav Gulis, Ludmila Marvanová & Enrique Descals) -- Chapter26. Sporulation by Aquatic Hyphomycetes (Felix Bärlocher) -- Chapter 27. Ergosterol as a Measure of Fungal Biomass (Mark O. Gessner) -- Chapter 28. Fungal Growth Rates and Production (Keller Suberkropp, Mark O. Gessner & Kevin A. Kuehn) -- Chapter 29. Bacterial Abundance and Biomass Determination in Plant Litter by Epifluorescence Microscopy (Nanna Buesing & Mark O. Gessner) -- Chapter 30. Growth and Production of Litter-Associated Bacteria (Nanna Buesing, Mark O. Gessner & Kevin A. Kuehn) -- Chapter 31. Isolation of Cellulose-Degrading Bacteria (Jürgen Marxsen) -- Chapter 32. ATP as a Measure of Microbial Biomass (Manuela Abelho) -- Chapter 33. Respiration of Litter-Associated Microbes and Invertebrates (Manuel A.S. Graça & Manuela Abelho) -- Part 4. Molecular Microbial Community Analyses. Chapter34. Terminal Restriction Fragment Length Polymorphism (T-Rflp) to Estimate Fungal Diversity (Liliya G. Nikolcheva & Felix Bärlocher) -- Chapter 35. Denaturing Gradient Gel Electrophoresis (DGGE) to Estimate Fungal Diversity (Liliya G. Nikolcheva & Felix Bärlocher) -- Chapter36. Quantitative Real-Time PCR (qPCR) to Estimate Molecular Fungal Abundance (Christiane Baschien & J. Steffen C. Carl) -- Chapter 37. Metabarcoding of Litter-associated Fungi and Bacteria (Sofia Duarte, Christian Wurzbacher & Sahadevan Seena) -- Chapter 38. Identifying Active Members of Litter Fungal Communities by Precursor rRNA (Martina Štursová & Petr Baldrian) -- Chapter 39. Gene Expression Analysis of Litter-Associated Fungi Using RNA-Seq (Elizabeth C. Bourne, Paul R. Johnston, Elisabeth Funk & Michael T. Monaghan) -- Chapter 40. Metaproteomics of Litter-associated Fungi (Katharina M. Keiblinger & Katharina Riedel) -- Part 5. Enzymatic Capabilities. Chapter 41. Extractellular Fungal Hydrolytic Enzyme Activity (Shawn D. Mansfield) -- chapter 42. Cellulases (Martin Zimmer) -- Chapter 43. Viscosimetric Determination of Endocellulase Activity (Björn Hendel & Jürgen Marxsen) -- Chapter 44. Fluorometric Determination of The Activity of β-Glucosidase and other Extracellular Hydrolytic Enzymes (Björn Hendel & Jürgen Marxsen) -- Chapter 45. Pectin-degrading Enzymes: Polygalacturonase and Pectin Lyase (Keller Suberkropp) -- chapter 46. Lignin-degrading Enzymes: Phenoloxidase and Peroxidase (Björn Hendel, Robert L. Sinsabaugh & Jürgen Marxsen) -- Chapter 47. Phenol Oxidation (Martin Zimmer) -- Chapter 48. Proteinase Activity: Azocoll and Thin-layer Enzyme Assay (Manuel A.S. Graça & Felix Bärlocher) -- Part 6. Litter Consumers. Chapter 49. Processing of Aquatic Invertebrates Colonizing Decomposing Litter (John S. Richardson) -- chapter 50. Identifying Stream Invertebrates as Plant Litter Consumers (Luz Boyero, Richard G. Pearson, Ricardo J. Albariño, Marcos Callisto, Francisco Correa-Araneda, Andrea C. Encalada, Marcelo Moretti, Alonso Ramírez, April Sparkman, Christopher M. Swan, Catherine M. Yule & Manuel A.S. Graça) -- chapter 51. Shredder Feeding and Growth Rates (Manuel A.S. Graça & José M. González) -- chapter 52. Feeding Preferences (Cristina Canhoto, Manuel A.S. Graça & Felix Bärlocher) -- chapter 53. Energy Budget of Shredders (Manuel A.S. Graça) -- chapter 54. The Role of Shredders in Litter Dynamics at Stream Scale (José M. González & Manuel A.S. Graça) -- Part 7. Litter Manipulations. Chapter 55. Manipulation of Leaf Litter Stoichiometry (Julio Arce-Funck, Vincent Felten, Michael Danger) -- Chapter 56. Isotopic Labelling of Leaf-litter Nitrogen (Bernd Zeller, Severine Bienaimé & Etienne Dambrine) -- Chapter 57. Decomposition and Consumption Tablets (DECOTABSs) (Gea H. van Der Lee, Ellard R. Hunting, J. Arie Vonk & Michiel H.S. Kraak) -- chapter 58. Inoculation of Leaf Litter with Aquatic Hyphomycetes (Eric Chauvet) -- Part 8. Data Analyses. Chapter 59. A Primer for Statistical Analysis (Felix Bärlocher) -- Chapter 60. Determining Temperature-normalized Decomposition Rates (Mark O. Gessner & Frank Peeters) -- Chapter 61. Biodiversity Analysis (Felix Bärlocher) -- Chapter 62. A Bioinformatics Primer for the Analysis of Illumina MiSeq Data of Litter-associated Fungi and Bacteria (Sahadevan Seena, Sofia Duarte & Christian Wurzbacher) -- Chapter 63. A Primer for Meta-Analysis (Verónica Ferreira & Felix Bärlocher).
    Abstract: This edited volume is an extensive collection of methods for investigating plant litter dynamics in ecosystems. Particular emphasis is placed on litter decomposition in streams and rivers. The presented methods range from analyses of chemical and physical litter properties to the taxonomic and functional characterization of microbial decomposers, both fungi and bacteria, assessments of litter-consuming invertebrates, and procedures to determine litter dynamics at the stream ecosystem level. Several chapters addressing general topics of data analysis are also included. This second edition of the book has been greatly expanded. Its now 63 chapters cover both well-established and recently elaborated techniques, some of which have not yet been applied to decomposing litter in streams. Modern molecular techniques ranging from next-generation sequencing to proteomics receive special attention among the 20 chapters that are entirely new. Numerous methods on characterizing litter consumers have also been added to fill an evident gap of the first edition. However, the basic original concept and all of the previous chapters have been retained, although most of them have been thoroughly updated. Typical contributions provide step-by-step protocols that are preceded by brief reviews of the ecological significance and the principles underlying the method. Where available, short compilations of published data have been added in overview tables to provide background information on the range of results to expect. Useful hints, a discussion of potential weaknesses, and key references are provided at the end. Hands-on material useful to implement several of the presented methods (e.g. computer code, calculation sheets) is available online. The book is written for students embarking on studies of plant litter dynamics and for established researchers wishing to expand the scope of their methodological toolbox to study litter decomposition and the microbial decomposers and invertebrates involved in the process. The primary intended audience is aquatic ecologists, since many of the methods presented in the book focus on streams and stream organisms. However, the great majority of the protocols can be easily adapted or even directly applied to coastal and terrestrial ecosystems. Consequently, they should be of equal interest to scientists investigating plant litter dynamics in habitats such as mangroves and salt-marshes, terrestrial grasslands and forests.
    Type of Medium: Online Resource
    Pages: XXV, 604 p. 89 illus., 37 illus. in color. , online resource.
    Edition: 2nd ed. 2020.
    ISBN: 9783030305154
    DDC: 577
    Language: English
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  • 87
    Keywords: Biotic communities. ; Agriculture. ; Physical geography. ; Earth sciences. ; Ecosystems. ; Agriculture. ; Earth System Sciences. ; Earth Sciences.
    Description / Table of Contents: Executive Summary -- Overview and Purposes -- Key Message -- Chapter 1. State Of Forest And Rangeland Soils Research In The United States (Dan Binkley, Daniel D. Richter, Richard V. Pouyat, and Linda Geiser) -- Chapter 2. Soil Carbon (Erin Berryman, Jeff Hatten, Deborah S. Page-Dumroese, Kate Heckman, David D’Amore, Jennifer Puttere, Michael SanClements, Stephanie Connolly, Charles H. (Hobie) Perry, and Grant Domke) -- Chapter 3. Soils And Water (Mary Beth Adams, Vince Archer, Scott Bailey, Kevin McGuire, Chelcy Miniat, Dan Neary, Toby O’Geen, Pete Robichaud, and Mike Strobel) -- Chapter 4. Biogeochemical Cycling In Forest And Rangeland Soils Of The United States (Lindsey E. Rustad, Jennifer Knoepp, Daniel D. Richter, and Andrew Scott) -- Chapter 5. Forest And Rangeland Soil Biodiversity (Stephanie A. Yarwood, Elizabeth Bach, Matt Busse, Jane E. Smith, Mac A. Callaham, Jr., Chih-Han Chang, Taniya Roy Chowdhury, and Steven D. Warren) -- Chapter 6. Wetland And Hydric Soils (Carl Trettin, Randall Kolka, Anne Marsh, Sheel Bansal, Eric Lilleskov, Patrick Megonigal, Marla Stelk, Graeme Lockaby, David D’Amore, Richard MacKenzie, Brian Tangen, Rodney Chimner, and James Gries) -- Chapter 7. Urban Soils (Richard Pouyat, Susan Day, Sally Brown, Kirsten Schwarz, Richard Shaw, Katalin Szlavecz, Tara Trammell, and Ian Yesilonis) -- Chapter 8. Soil Management And Restoration (Mary Williams, Cara Farr, Deborah Page-Dumroese, Stephanie Connolly, and Eunice Padley) -- Chapter 9. Soil Mapping, Monitoring, And Assessment (Mark J. Kimsey, Larry E. Laing, Sarah Anderson, Jeff Bruggink, Steve Campbell, David Diamond, Grant Domke, James Gries, Scott Holub, Greg Nowacki, Deborah Page-Dumroese, Charles H. (Hobie) Perry, Lindsey Rustad, Kyle Stephens, and Robert Vaughan) -- Chapter 10. Challenges And Opportunities (Linda Geiser, Toral Patel-Weynand, Anne Marsh, Korena Mafune, and Daniel Vogt) -- Appendix A: Regional Summaries -- Appendix B: Soils Networks And Resources -- Appendix C: Summary Of Research Questions.
    Abstract: This open access book synthesizes leading-edge science and management information about forest and rangeland soils of the United States. It offers ways to better understand changing conditions and their impacts on soils, and explores directions that positively affect the future of forest and rangeland soil health. This book outlines soil processes and identifies the research needed to manage forest and rangeland soils in the United States. Chapters give an overview of the state of forest and rangeland soils research in the Nation, including multi-decadal programs (chapter 1), then summarizes various human-caused and natural impacts and their effects on soil carbon, hydrology, biogeochemistry, and biological diversity (chapters 2–5). Other chapters look at the effects of changing conditions on forest soils in wetland and urban settings (chapters 6–7). Impacts include: climate change, severe wildfires, invasive species, pests and diseases, pollution, and land use change. Chapter 8 considers approaches to maintaining or regaining forest and rangeland soil health in the face of these varied impacts. Mapping, monitoring, and data sharing are discussed in chapter 9 as ways to leverage scientific and human resources to address soil health at scales from the landscape to the individual parcel (monitoring networks, data sharing Web sites, and educational soils-centered programs are tabulated in appendix B). Chapter 10 highlights opportunities for deepening our understanding of soils and for sustaining long-term ecosystem health and appendix C summarizes research needs. Nine regional summaries (appendix A) offer a more detailed look at forest and rangeland soils in the United States and its Affiliates.
    Type of Medium: Online Resource
    Pages: XXVI, 289 p. 86 illus., 71 illus. in color. , online resource.
    Edition: 1st ed. 2020.
    ISBN: 9783030452162
    DDC: 577
    Language: English
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  • 88
    Keywords: Biotic communities. ; Geographic information systems. ; Landscape ecology. ; Urban ecology (Biology). ; Climatology. ; Ecosystems. ; Geographical Information System. ; Landscape Ecology. ; Urban Ecology. ; Climate Sciences.
    Description / Table of Contents: Preface -- Multiple Perspectives on Eurasian Drylands -- Dry Land Belt of Northern Eurasia: Contemporary Environmental Changes -- Recent Land Surface Dynamics in Greater Central Asia -- Quantifying the Anthropogenic Signature in Drylands of Central Asia and Its Impact on Water Scarcity and Dust Emissions -- The Complexity and Challenges of Central Asia’s Water-Energy-Food Systems -- Assessment of the influences of dust storms on cotton production in Tajikistan -- Population and Urban Dynamics in Drylands of China -- Hydrology and Erosion Risk Parameters for Grasslands in Central Asia -- A Conceptual Framework for Ecosystem Stewardship Based on Landscape Dynamics: Case Studies From Kazakhstan and Mongolia -- Social-Ecological Systems across the Asian Drylands Belt (ADB) -- Index.
    Abstract: This volume is a compilation of studies on interactions of changes in land cover, land use and climate with people, societies and ecosystems in drylands of Greater Central Asia. It explores the effects of collapse of socialist governance and management systems on land use in various parts of Central Asia, including former Soviet Union republics, Mongolia and northern drylands of China. Often, regional land-atmosphere feedbacks may have large global importance. Remote sensing is a primary tool in studying vast dryland territories where in situ observations are sporadic. State-of-the-art methods of satellite remote sensing combined with GIS and models are used to tackle science questions and provide an outlook of current changes at land surface and potential scenarios for the future. In 10 chapters, contributing authors cover topics such as water resources, effects of institutional changes on urban centers and agriculture, landscape dynamics, and the primary drivers of environmental changes in dryland environment. Satellite observations that have accumulated during the last five decades provide a rich time series of the dynamic land surface, enabling systematic analysis of changes in land cover and land use from space. The book is a truly international effort by a team of scientists from the U.S., Europe and Central Asia. It is directed at the broad science community including graduate students, academics and other professionals at all levels within natural and social sciences. In particular, it will appeal to geographers, environmental and social scientists, economists, agricultural scientists, and remote sensing specialists.
    Type of Medium: Online Resource
    Pages: XV, 230 p. 95 illus., 76 illus. in color. , online resource.
    Edition: 1st ed. 2020.
    ISBN: 9783030307424
    Series Statement: Landscape Series, 17
    DDC: 577
    Language: English
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  • 89
    Online Resource
    Online Resource
    Cham :Springer International Publishing :
    Keywords: Immunology. ; Cytology. ; Lipids. ; Diseases. ; Human physiology. ; Immunology. ; Cell Biology. ; Lipidology. ; Diseases. ; Human Physiology.
    Description / Table of Contents: Chapter 1. Introduction. What is an M2 macrophage? Historical overview of the macrophage polarization model. The Th1/Th2 and M1/M2 paradigms, the arginine fork -- Chapter 2. Evolutionary origin of the M2 macrophage activation: invertebrates -- Chapter 3. Evolution of M2 macrophage functions in chordates -- Chapter 4. Signal mechanisms of M2 macrophage activation -- Chapter 5. Mechanisms which control the size of M2 macrophage-dominated tissue macrophage niches -- Chapter 6.Immune functions of the M2 macrophages: host defense, self-tolerance and autoimmunity -- Chapter 7. M2 macrophages in the integument and in the musculoskeletal system -- Chapter 8. M2 macrophages in the circulatory-, respiratory and excretory organs -- Chapter 9. M2 macrophages in the metabolic organs and in the neuroendocrine system -- Chapter 10. Practical approaches in M2 macrophage biology: analysis, pharmacology and didactical interpretation of M2 macrophage functions.
    Abstract: Macrophages are core components of the innate immune system. Once activated, they may have either pro- or anti-inflammatory effects that include pathogen killing, safe disposal of apoptotic cells or tissue renewal. The activation state of macrophages is conceptualized by the so-called M1/M2 model of polarization. M2 macrophages are not simply antagonists of M1 macrophages; rather, they represent a network of tissue resident macrophages with roles in tissue development and organ homeostasis. M2 macrophages govern functions at the interfaces of immunity, tissue development and turnover, metabolism, and endocrine signaling. Dysfunction in M2 macrophages can ruin the healthy interplay between the immune system and metabolic processes, and lead to diseases such as insulin resistance, metabolic syndrome, and type 1 and 2 diabetes mellitus. Furthermore, M2 macrophages are essential for healthy tissue development and immunological self-tolerance. Worryingly, these functions of M2 macrophages can also be disrupted, resulting in tumor growth and autoimmunity. This book comprehensively discusses the biology of M2 macrophages, summarizes the current state of knowledge, and highlights key questions that remain unanswered.
    Type of Medium: Online Resource
    Pages: XIII, 224 p. 1 illus. , online resource.
    Edition: 1st ed. 2020.
    ISBN: 9783030504809
    Series Statement: Progress in Inflammation Research, 86
    DDC: 571.96
    Language: English
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  • 90
    Online Resource
    Online Resource
    Cham :Springer International Publishing :
    Keywords: Immunology. ; Diseases. ; Proteins. ; Human physiology. ; Cancer. ; Immunology. ; Diseases. ; Proteins. ; Human Physiology. ; Cancer Biology.
    Description / Table of Contents: C-type lectin receptors in phagocytosis -- C-type lectins in immunity to lung pathogens -- Signalling C-type lectins in antifungal immunity -- Dendritic cell immunoactivating receptor: an activating receptor for mycobacteria -- myeloid C-type lectin receptors sensing tissue damage -- 3D structure and ligand recognition of C-type lectins -- Mechanisms and Functions of CARD9 Signaling in the Innate Immune System.
    Abstract: This book focuses on C-type lectin receptors, a newly emerging family of pattern-recognition receptors (PRRs) and a crucial part of the human innate immune system. Above all, the authors highlight these receptors’ role in the recognition of pathogen-associated molecular patterns (PAMPs) and damage-associated molecular patterns (DAMPs) – one of the first steps in responding to foreign and potentially dangerous structures in the human body. The respective chapters chiefly examine various C-type lectin receptors, their corresponding ligands, and signalling. In addition to offering immunologists and clinicians important insights from the latest research, they may also provide novel points of departure for future drug development.
    Type of Medium: Online Resource
    Pages: V, 203 p. 60 illus., 30 illus. in color. , online resource.
    Edition: 1st ed. 2020.
    ISBN: 9783030622374
    Series Statement: Current Topics in Microbiology and Immunology, 429
    DDC: 571.96
    Language: English
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  • 91
    Online Resource
    Online Resource
    Cham :Springer International Publishing :
    Keywords: Ecology . ; Ecology.
    Abstract: Charles S. Elton’s classic text Ecology of Invasions by Animals and Plants sounded an early warning about a human-driven global change that became widely appreciated among scientists and the public only decades later. "We must make no mistake", he wrote. "We are seeing one of the great historical convulsions of the world's fauna and flora." The enormous environmental consequences of this phenomenon are now well recognized. The past 60 years have seen an exponential rise in research on biological invasions, and Elton’s original hypotheses are among those at the center of this research. In this new annotated edition, ecologists Daniel Simberloff and Anthony Ricciardi have provided forewords placing each chapter into historical scientific context. They assess the influence of Elton’s ideas on the development of invasion ecology. Moreover, using the author’s notes from the Elton archives at the University of Oxford, Simberloff and Ricciardi offer evidence that Elton was preparing the groundwork for a revised edition and discuss what additions and changes he intended to make. With clear language and copious examples, Ecology of Invasions is the first book to place invasions in a global context and is still the most cited work on the subject. It is an essential reference for students, researchers, and the general public who wish to understand an environmental phenomenon that has grown in magnitude and scope as a global issue for conservation and biosecurity.
    Type of Medium: Online Resource
    Pages: XXI, 261 p. 100 illus. , online resource.
    Edition: 2nd ed. 2020.
    ISBN: 9783030347215
    DDC: 577
    Language: English
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  • 92
    Online Resource
    Online Resource
    Cham :Springer International Publishing :
    Keywords: Immunology. ; Medicine Research. ; Biology Research. ; Medical microbiology. ; Cytology. ; Biochemistry. ; Immunology. ; Biomedical Research. ; Medical Microbiology. ; Cell Biology. ; Biochemistry.
    Description / Table of Contents: An introduction to phagocytosis -- A Brief History of Phagocytosis -- The role of membrane surface charge in phagocytosis -- Receptor models of phagocytosis: the effect of target shape -- Decision Making in Phagocytosis -- Membrane tension and the role of ezrin during phagocytosis -- Molecular mechanisms of calcium signaling during phagocytosis -- Calpain activation by Ca2+ and its role in phagocytosis -- The NADPH oxidase and the phagosome -- Conclusions and the future of phagocytosis.-.
    Abstract: Phagocytosis is the engulfment of particulate matter by cells. It is a fundamental (and probably “primitive”) cell biological process which is important in single celled organisms such as amoeba; multicellular animals including coelenterates; and in higher animals. In humans and other mammals, specialised immune cells (phagocytes) utilise phagocytosis in their crucial role of engulfing and destroying infecting microbes. Yet, surprisingly, the biophysics and biochemistry underlying the process has only become clear recently with the advent of genetic manipulation and advances in single cell imaging. In this volume, the aim is to bring together recent fundamental advances that give a clear picture of the underlying mechanism involved in phagocytosis. Not only is this an important topic in its own right, but a full understanding of the process will have a potential impact on human medicine, since as antibiotics become less effective in fight infection, researchers are looking at alternative approaches, including enhancing the “natural” immunity brought about by immune phagocytes. The aim is to provide a comprehensive volume on the topic, with separate chapters on identified recent advances, each written by the major contributors in each area. In addition, the volume will attempt to give a wider overview than is often the case in single author reviews, with an emphasis here on the cell biological understanding of phagocytosis using biophysical approaches alongside the biochemical and imaging approaches.
    Type of Medium: Online Resource
    Pages: X, 189 p. 66 illus., 58 illus. in color. , online resource.
    Edition: 1st ed. 2020.
    ISBN: 9783030404062
    Series Statement: Advances in Experimental Medicine and Biology, 1246
    DDC: 571.96
    Language: English
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  • 93
    Online Resource
    Online Resource
    Cham :Springer International Publishing :
    Keywords: Ecology . ; Evolution (Biology). ; Geotechnical engineering. ; Population biology. ; Paleontology . ; Coevolution. ; Evolutionary Ecology. ; Evolutionary Theory. ; Geotechnical Engineering and Applied Earth Sciences. ; Population Dynamics. ; Paleontology. ; Coevolution.
    Description / Table of Contents: Prologue -- Chapter 1 Introduction to Neotectonics and Bioregionalisation -- Chapter 2 Traversing Terranes: The Australides -- Chapter 3 Neotectonics and Australian Biogeography -- Chapter 4: Biotectonics: Making and Breaking Barriers -- Epilogue -- Glossary -- Appendix.
    Abstract: Tectonic plates are constantly moving, either crashing into one another creating a mosaic of mountains and shallow seas, or tearing apart and isolating large swathes of land. In both cases plate tectonics separates populations leading to the evolution of biota. Tectonics is also responsible for the destruction life, for instance when large coral reefs or shallow seas are compressed to form mountain peaks. Could recent research into these processes provide enough evidence to show that tectonics may be the ultimate driver of life on Earth? Our book delves into the current research in tectonics, particularly neotectonics, and its impact on rapid changes on biogeographical classification, also known as bioregionalisation. We also introduce a new term biotectonics that studies the impact of tectonics on biogeoregionalisation. The question we ask is how tectonics directly influences the distribution of biota in four case studies: the Mesozic and early Palaeogene Australides, which spans the Proto-Pacific coast of the South America, Antaractica and Australiasia; and the Neogene of Australia. To conclude we examine the role of neotectonics on tranistion zones and the Amazon Basin and make a case for biotectonic extinction. .
    Type of Medium: Online Resource
    Pages: XII, 67 p. 16 illus., 5 illus. in color. , online resource.
    Edition: 1st ed. 2020.
    ISBN: 9783030517731
    Series Statement: SpringerBriefs in Evolutionary Biology,
    DDC: 577
    Language: English
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  • 94
    Keywords: Immunology. ; Psychiatry. ; Gynecology . ; Diseases. ; Neurosciences. ; Psychobiology. ; Human behavior. ; Immunology. ; Psychiatry. ; Gynecology. ; Diseases. ; Neuroscience. ; Behavioral Neuroscience.
    Description / Table of Contents: Chapter 1. Perinatal psychiatry: ready for prime time?- Chapter 2. Pregnancy, stress response and neuroinflammation: effects on offspring and risk for psychiatric disorders -- Chapter 3. Epigenetic modifications of early life stress and adult life psychopathology -- Chapter 4. Perinatal HPA programming and adult psychopatholgoy -- Chapter 5. Intergeneration transmission of depression: focus on inflammation -- Chapter 6. Neonatal bacterial meningitis: mechanisms and implications for adult life psychopathology -- Chapter 7. Toxoplasmosis as risk factor for severe psychiatric disorders: clinical and pre-clinical evidence -- Chapter 8. A critical appraisal on the epidemiological evidence linking perinatal inflammation and risk of psychosis -- Chapter 9. Maternal Immune Activation as a Risk Factor for Schizophrenia: Evidence from Preclinical and Clinical Studies -- Chapter 10. Influences of sex and age in MIA-induced behavioral and neurobiological alterations -- Chapter 11. MIA and autism -- Chapter 12. Zika virus infection and neuropsychiatric complications -- Chapter 13. Placenta immunology: impact on fetus development -- Chapter 14. Placenta and cord blood as source of immune markers of offspring development and psychopathology -- Chapter 15. Cytokine model of cognitive function.
    Abstract: Perinatal psychiatry is an emerging field that investigates the role of perinatal events – for example pregnancy complications and infections – in the development of neuropsychiatric conditions, such as schizophrenia and mood disorders. Among the implicated pathological mechanisms, perinatal-induced inflammation seems to play a major role and is being considered as a potential target for therapeutic intervention. Bringing together various approaches in the field (preclinical and clinical, epidemiological, immunological and genetic methods), the book discusses the available evidence, the putative mechanisms and the challenges ahead.
    Type of Medium: Online Resource
    Pages: XI, 268 p. 1 illus. , online resource.
    Edition: 1st ed. 2020.
    ISBN: 9783030393359
    Series Statement: Progress in Inflammation Research, 84
    DDC: 571.96
    Language: English
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  • 95
    Keywords: Ecology . ; Engineering. ; Bioethics. ; Conservation biology. ; Ecology. ; Technology and Engineering. ; Bioethics. ; Conservation Biology.
    Description / Table of Contents: Part I. General Concepts -- 1. From Parks for Landscapes: Reading of a Long Process -- 2. Landscape: Re-assessing the Conservation Paradigm -- 3. Biodiversity Conservation in Human-prone Landscapes: Social and Ethical Issues -- 4. Landscapes require new Legal Framework to Conserve Biodiversity -- Part II. Data to Support the Conservation Action -- 5. Qualitatively Describing Forests of the Landscape -- 6. Bonobos in the Lake Tumba: Describing the Landscape Species -- 7. Genetics of Bonobos in the Lake Tumba Landscape -- 8. Forest Refugia Theory, Density-Dependence and Stress Syndrome and the Proto-pan -- 9. Wild Bonobos and Wild Chimpanzees and Human Diseases -- 10. Alternative Cheaper Methods to Estimate Bonobos -- 11. Chimpanzees of the Ngiri Triangle -- 12. Lions of Malebo: Population and Conflicts with Humans -- 13. Diurnal Primates: Estimates and Conservation Issues -- 14. Elephants in Lake Tumba Landscape: Malebo, Ngiri and Bolombo-Losombo -- 15. Developing a Threat Index for Documented Large Mammal Species -- 16. Synopsis of Freshwaters, Species Diversity and Conservation Issues -- 17. An Abridgement of the Birds Throughout the Diversity of Habitats -- Part III. Not Only Biodiversity but also Human Communities -- 18. The Political Economy of Landscape -- 19. Assessing the Needs in Lands in the Lake Tumba Landscape -- Part IV. Using the Data to Strategize and Manage the Landscape -- 20. Planning for the Management of the Landscape -- 21. Setting Habitats Aside for Biodiversity Conservation -- 22. Protected Areas: Defining the Optimum Law Enforcement Resources -- 23. Planning to Mobilization of Resources via Sustainable Tourism -- 24. Decent Knowledge for Future Directions in the Landscape Management -- 25. Are there Good Ethical Reasons to Preserve Biodiversity at the Expense of the Needs of Local Communities Who Could Benefit from Exploiting those Natural Resources?
    Abstract: Protected areas have often been defined as the backbones of biodiversity conservation. However, legitimate demands formulated by countries for their economic development, growing human populations, forest fragmentations, and needs of local communities for sustainable livelihoods are also pressing demands on protected areas, stringently pressuring conservation community to identify means to reconcile long term biodiversity conservation and communities’ livelihoods. Hence, integrating conservation activities within the global framework of economic development of countries with high biodiversity had become part of conservation paradigms. Integrated development as a route to conservation, strict protected areas, community managed areas, etc. have been tried but resulted in debatable outcomes in many ways. The lukewarm nature of these results brought ‘landscape approach’ at the front of biodiversity conservation in Central Africa. Since the late 1990s the landscape approach uses large areas with different functional attributes and shifts foundational biodiversity conservation paradigms. Changes are brought to the role traditionally attributed to local communities, aligning sustainable development with conservation and stretching conservation beyond the confines of traditional protected areas. These three shifts need a holistic approach to respond to different conservation questions. There are only a few instances where the landscape experience has been scientifically documented and lessons learnt drawn into a corpus of knowledge to guide future conservation initiatives across Central Africa. To subjugate one biodiversity conservation landscape as one case study emerged as a matter of urgency to present the potential knowledge acquired throughout the landscape experiment, including leadership and management, processes tried, results (at least partially) achieved, and why such and such other process or management arrangement were been chosen among many other alternatives, etc. The challenges of the implementation of the conservation landscape approach needed also to be documented. This book responds to the majority of these questions; drawing its content from the firsthand field knowledge, it discusses these shifts and documents what has been tried, how successful (unsuccessful) it was, and what lessons learnt from these trials. Theoretical questions such as threat index, and ecological services, etc. are also discussed and gaps in knowledge are identified.
    Type of Medium: Online Resource
    Pages: XV, 382 p. 12 illus., 5 illus. in color. , online resource.
    Edition: 1st ed. 2020.
    ISBN: 9783030387280
    Series Statement: Environmental History, 12
    DDC: 577
    Language: English
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