ALBERT

Description / Table of Contents: Chapter 1 Introduction -- Chapter 2 Unconventional functions of transcription factors -- GAGA transcription factor -- Heterochromatin protein 1 -- Retinoblastoma protein -- STAT -- ATF-2 -- NF-kB -- Chapter 3 STAT and HP1, in their unconventional roles, promote longevity and protect against DNA damage and cancer -- STAT and HP1 promote longevity -- STAT and HP1 protect against DNA damage -- Increased levels of STAT and HP1 hinder carcinogenesis in a mouse xenograft model -- Chapter 4 The possible biological significance of transcription factors’ unconventional functions -- The epigenome -- Processes in the cell nucleus -- Future Work.

Description / Table of Contents: Introduction (MCG and FN) -- Updates on ATMP regulations from EU: experience with PRIME procedure and list of approved ATMP -- EU portal for clinical trials application -- European Pharmacopoeia texts on gene therapy medicinal products -- Updates on ATMP regulations from UK after Brexit and list of approved ATMP -- Updates on ATMP regulations from Switzerland and list of approved ATMP -- Updates on ATMP regulations from US FDA: experience with breakthrough/accelerated procedures and list of approved ATMP -- Updates on ATMP regulations from Canada and list of approved ATMP -- Updates on ATMP regulations from Brasil and list of approved ATMP -- Updates on ATMP regulations from Singapore and list of approved ATMP -- Updates on ATMP regulations from Japan: experience with new law and list of approved ATMP -- Updates on ATMP regulations from South Korea and list of approved ATMP -- Updates on ATMP regulations from Taiwan and list of approved ATMP -- Updates on ATMP regulations from Thailand and list of approved ATMP -- ATMP regulations in China and list of approved ATMP -- ATMP regulations in Australia and list of approved ATMP -- ATMP regulations in India and list of approved ATMP -- International harmonization programs. .

Description / Table of Contents: The Art of Cell Therapy -- Scope and Applicability of Autologous Cell Therapies -- Scale and Accessibility of Allogeneic Cell Therapies -- Acellular Stem Cell Products. Potency Assays: The Buggy Boo of Stem Cell Therapy -- Potency Assay Development: A Keystone for Clinical Use -- Quantifying Critical Quality Attributes -- Advanced Technologies for Potency Assay Measurement -- Potency Quality by Design: Tailoring for Specific Therapy -- Contract Research Organizations Expediting Therapeutic Availability -- Regulatory Authority Perspectives for Potency Release Criteria -- Illustrative Potency Assay Examples from Approved Therapies -- The Integrity of Potency Assays and Safe Intervention -- The Evolving Landscape of Potency Assays.

Description / Table of Contents: 1 Introduction -- Part I: Forest and woodland biomes -- 2 White sand ecosystems in the Amazon basin: geographic distribution, distinctive features, and ecology. An overview -- 3 The forests of the Rio Negro basin in the north-western Amazon: a phytosociological classification -- 4 Amazon caatinga complex: sclerophyllous vegetation on nutrient-poor white sand soils -- Part II: Meadow biomes -- 5 Mapping white-sand ecosystems by integrating Global PALSAR-2 and SENTINEL-1 with NDVI (LANDSAT data) -- 6 The study areas: landscapes and soils -- 7 Soil properties, formation, distribution, and classification -- 8 Origin and sources of sand: from highlands to lowlands -- 9 Sand dynamics and distribution: a geo-sedimentological approach -- 10 Features and trends of meadow landscape evolution -- 11 Meadow phytodiversity: flora, endemism, vegetation types, and geographic distribution patterns -- 12 Synthesis: white-sand and meadow-vegetation relationships.

Description / Table of Contents: Brain Tissue Oxygen and BOLD fMRI Under Different Levels Of Neuronal Activity -- Cerebral Microcirculation and Oxygenation Modulation by Transcranial Alternating Current Stimulation in Awake and Anesthetized Mice -- The Effect of Hypercapnia on Cortical Metabolic Rate and Mitochondrial Redox Status -- Relationship Between Left-Right Dominancy of Prefrontal Cortex Activity and Heart Rate During Rest and Task Periods: An fNIRS Study -- Relationship Between Cognitive Function, Oral Conditions and Systemic Metabolic Function in the Elderly -- Pro-survival Phenotype of HIF-1α: Neuroprotection through Inflammatory Mechanisms -- Infradian Rhythms in Cerebrovascular Oxygenation and Blood Volume in Humans at Rest: A 5-year Study -- Mechanisms of Photostimulation of Brain’s Waste Disposal System: the Role of Singlet Oxygen -- Changes of Arterial and Venous Cerebral Blood Flow Correlation in Moderate-to-Severe Traumatic Brain Injury: A CT Perfusion Study -- Cerebral Net Water Uptake in Posttraumatic Cerebral Ischemia -- Brainstem Damage Underlies Changes in Hypoxic Ventilatory Response following Cardiac Arrest and Resuscitation in Rats -- Differences Between Good, Moderate and Poor Performers of a Verbal Fluency Task under Blue Light Exposure: An SPA-fNIRS Study -- Sex-specific and Dose-dependent Effects of Drag-Reducing Polymers on Microcirculation and Tissue Oxygenation in Rats after Traumatic Brain Injury -- Accuracy of Tissue Oxygen Saturation Measurements of a Textile-based NIRS Sensor -- Understanding the Role of Caveolae in Oxygen Buffering: The Effect of Membrane Curvature -- The Significance of Lipids for the Absorption and Release of Oxygen in Biological Organisms -- How Skin Color Depends on Tissue Oxygenation -- Tissue Concentration Analysis of Sulfur, Calcium and Oxygen in novel Skin Primo Nodes After Acupuncture -- Primo Vessels Inside Lymphatic Vessels are Absent in an ALS Mouse Model -- The Impact of Heterogeneous Cell Density in Hypoxic Tumors Treated with Radiotherapy -- A Critical Analysis of Possible Mechanisms for the Oxygen Effect in Radiation Therapy with FLASH -- Hyperhydration of Cancers: A Characteristic Biophysical Trait Strongly Increasing O2, CO2, Glucose and Lactate Diffusivities, and Improving Thermophysical Properties of Solid Malignancies -- No Difference in Muscle Basal Oxygenation in a Bedridden Population pre and Post Rehabilitation -- Relationship between Muscle Deoxygenation and Cardiac Output in Subjects without Attenuation of Deoxygenation Hemoglobin Concentration near the end of Ramp Cycling Exercise: A Longitudinal Study -- Image Reconstruction Using Deep Learning for Near-Infrared Optical Tomography: Generalization Assessment -- Neonatal Brain Temperature Monitoring Based on Broadband Near-Infrared Spectroscopy -- Time Domain Near-Infrared Optical Tomography Utilizing Full Temporal Data: A Simulation Study -- BIAN: A Multilayer Microfluidic-Based Tissue-Mimicking Phantom for Near-Infrared Imaging -- Do Vascular and Extracellular Measurements Consistently Reflect Intracellular pO2? Observation of Tissue Oxygenation Changes using Remote Photoplesysmography with a Smartphone -- Neurovascular, Metabolic, and Glymphatic Dynamics of the Brain Measured with fNIRS -- Imaging Cerebral Blood Vessels Using Near-Infrared Optical Tomography: A Simulation Study -- Reduced Cerebrovascular Oxygenation in Individuals with Post-Acute COVID-19 Syndrome (PACS) (“Long COVID”) -- Insufficient Oxygen Supplementation During Cardiopulmonary Resuscitation Leads to Unfavorable Biological Response While Hyperoxygenation Contributes to Metabolic Compensation -- Block of the Angiotensin Pathways Affects Flow-Volume Spirometry in Patients With SARS-CoV-2 Infection -- A Prospective Observational Pilot Study on the Effects of the Activity-based Stress Release Program on the Mental State and Autonomic Nervous System in Psychiatric patients. .

Description / Table of Contents: 1. What do we know about mammal movement in African tropical forests? -- 2. Movements patterns and population dynamics of giant forest hog groups in Kibale National Park, Uganda -- 3. Forest elephant movements in Central Africa – megafauna need megaspaces -- 4. Elephant movements, abundance and use of water sources in Kibale National Park, Uganda -- 5. Movement ecology and evolutionary history of forest buffalo -- 6. Site fidelity and home range shifts in a leaf-eating primate -- 7. Primate movements across the nutritional landscapes of Africa -- 8. Conditions facilitating a “landscape of fear from disease” in African forest mammals -- 9. Do seasonally frugivory and cognition shape foraging movements in wild western gorillas? -- 10. Females Move in Tight Crowds, Males Roam: Society and Movement Ecology of Mandrills -- 11. Linking Movement Ecology to Conservation Biology.

Description / Table of Contents: Introduction -- Biomes: Concepts, Characteristics and Terminology -- Profiles of Angola’s Biomes and Ecoregiens -- Landscapes: Geology, Hydrology and Geomorphology.

Description / Table of Contents: Part 1: Introduction to squirrels of the world and their conservation trends. Chapter 1: The World’s Squirrel Taxonomy -- Chapter 2: Evolution, habitat trends, and extinction rate estimates of the world squirrels -- Part 2: Squirrels of the world in the Anthropocene. Chapter 3: Habitat Trends and the Squirrel-Human Interface -- Chapter 4: A Meta-analysis based on Open Access Big Data Mining of Global Predicted Squirrel Distribution Models with Machine Learning for IUCN Conservation Status and Trend Policy Assessments -- Chapter 5: Squirrels in Cities -- Chapter : Squirrels in the Tropics -- Chapter 7: Squirrels on Islands -- Chapter 8: Tree squirrels in old-growth forests? -- Chapter 9: Can squirrels be used as indicators to identify and protect old-growth forest reserves? -- Chapter 10: Squirrel Economics -- Part 3: Problems and governance in the squirrel world. Chapter 11: Squirrel Hunting Regulations and Enforcement (Or Lack Thereof) -- Chapter 12: Where do the World’s Squirrel Hotspots and Coldspots of 230+ species go with Climate change 2100? -- Chapter 13: Squirrel’s marginalization and modern lack of conservation and poor sustainability outlook as a call to good action -- Part 4: First conclusions and the way forward. Chapter 14: A Conservation Management SWOT analysis for over 300 Squirrels of the World using 132 GIS layers confirming the PESTLE assessment -- Chapter 15: First Conclusions, Success stories, and Calls-to-action for the conservation of the world’s squirrels.

Description / Table of Contents: 1. Introduction to Rangeland Wildlife Ecology and Conservation -- Part I Rangeland Ecosystems and Processes -- 2. Rangelands of Western North America -- 3. A History of North American Rangelands -- 4. Western Rangeland Livestock Production Systems and Grazing Management -- 5. Manipulation of Rangeland Wildlife Habitats -- 6. Role and Management of Fire in Rangelands -- 7. Water is Life: Importance and Management of Riparian Areas for Rangeland Wildlife -- 8. Rangeland Biodiversity -- Part II Species Accounts -- 9. Prairie Grouse -- 10. Sage-Grouse -- 11. Quails -- 12. Rangeland Songbirds -- 13. Wetland Birds of Rangelands -- 14. Avian Predators in Rangelands -- 15. Burrowing Rodents -- 16. Mesocarnivores of Western Rangelands -- 17. Black-tailed and Mule Deer -- 18. White-tailed Deer -- 19. Pronghorn -- 20. Elk -- 21. Feral Equids -- 22. Mountain Ungulates -- 23. American Bison -- 24. Large Carnivores -- 25. Amphibians and Reptiles -- 26. Insects in Grassland Ecosystems -- Part III Social-Ecological Considerations -- 27. Wildlife, Rural Communities, and the Rangeland Livelihoods they Share: Opportunities in a Diverse Economies Approach -- 28. Living with Predators: A 20-year Case Study in the Blackfoot River Watershed of Montana -- 29. A Perspective on Rangeland and Wildlife Disciplines: Similarities Over Differences -- 30. Future of Rangeland Wildlife in North America.

Description / Table of Contents: Part I - Money and its role in the economy -- 1. Introduction: the world is on a collision course -- 2. What is money? -- 3. Money is like the ‘blood’ of the economy -- Part II Money and the unsustainability in stricto sensu -- 4. The growth imperative inherent in our financial system -- 5. The effect of the money interest rate on money supply, demand and growth -- 6. Economic growth in the long run is unsustainable -- 7. Economic growth or unemployment -- Part III. Money and inequality -- 8. Our current monetary system produces income inequality -- 9. Moral-ethic aspects of interest-induced inequality -- Part IV Natural money as solution -- 10. Gesell’s solution -- 11. Gesell’s Solution to achieve the SDGs -- 12. How to implement Gesell’s solution in today’s world -- 13. Alternatives to Gesell’s solution -- 14. Experiences with Gesell’s solution -- Part V Outlook and final considerations -- 15. Towards a Development at Human Scale -- 16. Economic resilience in presence of externals shocks -- 17. Final considerations.

Description / Table of Contents: 1- Basic concepts of ecology applied on the neotropic ecosystems -- 2 - Natural resources and sustainable development in Peru -- 3 - Classification of the Peruvian Ecosystems -- 4 - Peruvian ecosystems geography -- 5 - Biodiversity and endemism of the Andes -- 6 - Ecological communities, populations and metapopulations -- 7 - Succession and change of the ecosystems -- 8 - Biodiversity of the Amazonia Basin -- 9 - Peruvian protected natural areas -- 10 - The paramo ecosystems -- 11 - The Humboldt National Forest -- 12 - The Northwest Biosphere Reserve -- 13 - Urban ecosystems and development -- 14 - Climate changes -- 15 - Traditional land-use systems and agrobiodiversity in Peru -- Index.

Description / Table of Contents: Part 1: Knockouts and animal models -- Integrins α1β1 and α2β1 – The generalist collagen receptors -- Roles for Integrin α3β1 in Development and Disease -- Part 2: Fibrosis& Cancer -- Integrins: Key targets in tissue fibrosis and tumor stroma -- Integrins in Cardiac Form, Function and Disease -- Integrin 8 and its ligand nephronectin in health and disease -- v integrin-dependent TGF activation in cancer: a brief update -- Part 3: Human disease -- a11b1, a mesenchymal collagen-binding integrin with a central role in tissue- and tumor fibrosis -- Integrins in pathological tissue remodelling of joints -- α4 integrins in immune homeostasis and disease -- β2-integrins in immunity: new roles for old players -- Structure and function of the leukocyte integrin αMβ2 -- Part 4: Integrins in hemostasis, and immune control -- Platelet integrins: Critical mediators of haemostasis and pathological thrombus formation -- Integrins as receptors for bacterial and viral pathogens.

Description / Table of Contents: 1. Agro-biodiversity across the food chain -- 2. Emerging risks to plant health -- 3. Future-proofing Plants against Climate Change- A path to ensure Sustainable Food Systems -- 4. The role of Integrated Pest Management for sustainable food production: The soybean example -- 5. (Alternative approaches to pesticide use): Plant-derived pesticides -- 6. Antimicrobial use in animal food production -- 7. Impacts of environment-friendly unit operations on the functional properties of bee pollen -- 8. Microbiome applications for sustainable food systems -- 9. Healthier and sustainable food systems: integrating underutilized crops in a ‘Theory of Change Approach -- 10. Alternative proteins for food and feed.

Description / Table of Contents: Part I: Manufacturing of Recombinant Therapeutic Proteins -- Chapter 1. Single-Use Systems in Biopharmaceutical Manufacture: State of the Art and Recent Trends (Jossen et al.) -- Chapter 2. Recent Developments in Bioprocess Monitoring Systems (Rahmatnejad et al.) -- Chapter 3. Advances in Characterization of Industrial Bioreactors for Cell Culture Process (Fitschen et al.) -- Chapter 4. Continuous Bioprocessing for Upstream Process - Perfusion Process (Chotteau et al.) -- Chapter 5. Continuous Bioprocessing for Downstream (Gerstweiler) -- Chapter 6. Towards Digital Twin for Biopharmaceutical Processes: Concept and Progress (Ding et al.) -- Chapter 7. Integrated Process and Supply Chain Design and Optimization (Triantafyllou et al.) -- Chapter 8. Production of Complex Proteins in Plants – From Farming to Manufacturing (Nausch et al.) -- Chapter 9. Manufacturing of Recombinant Proteins Using Quality by Design (QbD) Methodology: Current Trend and Challenges (Shin and Landauer) -- Chapter 10. Biopharma 4.0 for Biologics Manufacturing Under Pandemic Constraints (Schmidt et al.) -- Chapter 11. Biopharma 4.0: Digital Technologies Driving Smart Manufacturing (Nargund et al.) -- Part II: Manufacturing Aspects of Cell and Gene Therapy -- Chapter 12. Essential Aspects of Mesenchymal Stem Cell Manufacturing (Fleischhammer et al.) -- Chapter 13. Towards a Continuous Production of Human Mesenchymal Stromal Cells in a Chemically Defined Medium: Opportunities and Challenges for a Robust and Scalable Expansion Process (Tasto and Salzig) -- Chapter 14. Biomanufacturing Aspects of Gene Therapy (Warnock) -- Chapter 15. Manufacturing and Quality of Advanced Therapeutics: Cellular Therapies, CAR-T and Gene Therapies (van den Bos et al.).

Description / Table of Contents: 1. Introduction. Randall W. Myster -- 2. Mountain gradients in the Neotropics, a bracken fern perspective. Jorge Luis Avila Nuñez, Maria Pia Calcagno-Pissarelli, Miguel E. Alonso-Amelot -- 3. Effects of agricultural expansion on lotic benthic macroinvertebrate communities: a review and case study from Brazil. Elaine C. Corrêa and Ryan M. Utz -- 4. Plant competition across topographic gradients in Neotropical Cerrado savannas: an isotopic approach. Davi R. Rossatto and Augusto C. Franco -- 5. Diversity of aquatic macroinvertebrates along altitudinal gradients in Colombian. Cesar E. Tamaris-Turizo, Gabriel A. Pinilla-A and Juan D. González-Trujillo -- 6. Intraspecific trait variability of emblematic grass and tree species from Venezuelan savannas across extended physical gradients. Zdravko Baruch -- 7. Latitudinal trends in scorpion assemblages of Brazilian Atlantic Forest: do the Rapoport’s and Bergmann’s rules apply? André F.A. Lira, Alessandra R.S. Andrade and Stênio I.A. Foerster -- 8. Species diversity of three faunal communities along a successional cloud forest gradient. Juan Manuel Díaz-García, Fabiola López-Barrera, Eduardo Pineda, Jorge Valenzuela-González and Adriana Sandoval-Comte -- -- 9. Ecohydrological gradient in Neotropical montane ecosystems: From tropical montane forests to glacier. Conrado Tobón, Erick Castro, and Jorge Luís Ceballos -- 10. Communities of small terrestrial arthropods change rapidly along a Costa Rican elevation gradient. M. Alex Smith, Connor Warne, Kate Pare, Sarah Dolson, Elyssa Loewen, Kelsey Jones, Megan McPhee, Lauren Stitt, Lauren Janke, Rebecca M. Smith, Heather Coatsworth, Alexandre M. M. C. Loureiro, Angel Solis, Carlos F. Viquez, Josephine Rodriguez, Jose Fernandez-Triana, Michael J. Sharkey, James Whitfield, Alejandro Masís, María Marta Chavarría, Roger Blanco, Felipe Chavarria, Eugenie Phillips-Rodríguez, Roberto Fernández, Dunia Garcia, Guillermo Pereira, Harry Ramirez, Manuel Pereira, Winnie Hallwachs and Daniel H. Janzen -- 11 Neotropical gradients of insect groups in Brazilian mountains. Lucas Neves Perillo, Frederico de Siqueira Neves, Flávio Siqueira de Castro and Ricardo Ribeiro de Castro Solar -- 12. Altitudinal Pattern of Soil Organic Carbon and Nutrients in a Tropical Forest in Puerto Rico. Dingfang Chen, Mei Yu, Grizelle González, Qiong Gao -- 13. Elevational and latitudinal species richness patterns of dung beetles in North and South America and the role played by historical factors. Jorge M. Lobo and José Gutiérrez -- 14. Diversity patterns of vascular plant groups along gradients of elevation and disturbance in Mexico. Jorge A. Gómez-Díaz, Alma P. Bautista-Bello, César I. Carvajal-Hernández, Valeria Guzmán-Jacob, María Leticia Monge-González and Thorsten Krömer -- 15 Gradients and the Structure of Neotropical Metacommunities: Effects of Disturbance -- Elevation, Landscape Structure, and Biogeography. Steven J. Presley, Michael R. Willig -- 16. Socioecological gradients: contesting traditional ecoclines to explain the high biocultural diversity of the Andean verdant. Fausto Sarmiento, Andreas Haller, Domenico Branca, Christiam Aguirre, Vladimir Kremsa, Carla Marchant, Masahito Yoshida -- 17. Conclusions, synthesis and future directions. Randall W. Myster.

Description / Table of Contents: Part. I. History, Recollections, And Homages -- Paradigm Shifts in the History of Nox2 and Its Regulators: An Appreciative Critique -- The Phagocyte Oxidase: The Early Years -- Reflections on My Life in Noxes -- The Discovery and Characterisation of Nox2, a Personal Journey -- Reminiscences on Positional Cloning of X-CGD Gene (Aka CYBB, gp91phox, Nox2) -- On Katsuko Kakinuma: Spectroscopic Studies of Redox Centers in NADPH Oxidase “Identifying and Observing the Key Players That Pass an Electron to Oxygen” -- Pierre Vignais, from One Respiratory Chain to Another -- Gary M. Bokoch, the Rac-n-Rho Man: His fascination with Rho-GTPases -- History and Discovery of the Noxes: From Nox1 to the DUOXes -- Part. II. Canonical NADPH Oxidases -- NADPH Oxidase 1: At the Interface of the Intestinal Epithelium and Gut Microbiota -- Physiological Functions and Pathological Significance of NADPH Oxidase 3 -- Nox 4: From Discovery to Pathophysiology -- Nox5 - Molecular Regulation and Pathophysiology -- DUOX1 and DUOX2, DUOXA1 and DUOXA2 -- Part. III. NADPH Oxidase Regulators -- p47phox and NOXO1, the Organizer Subunits of the NADPH Oxidase 2 (Nox2) and NADPH Oxidase 1 (Nox1) -- The NADPH Oxidase Activator p67phox and Its Related Proteins -- p40phox: Composition, Function and Consequences of Its Absence -- Rho Family GTPases and their Modulators -- Part IV. Tools, Inhibitors, and Neighbors -- Tools to Identify Noxes and their Regulators -- Methods to Measure Reactive Oxygen Species Production by NADPH Oxidases -- Isoform-Selective Nox Inhibitors: Advances and Future Perspectives -- Proteins Cross-talking with Nox Complexes: The Social Life of Noxes -- Part V. Non-Mammalian NADPH Oxidases -- NADPH Oxidase-Dependent Processes in the Social Amoeba Dictyostelium Discoideum -- Discovery and Functional Analysis of the Single-Celled Yeast NADPH Oxidase, Yno1 -- NADPH Oxidases in Fungi -- Plant NADPH Oxidases -- Nematode Noxes: The DUOXes of Caenorhabditis elegans -- NADPH Oxidases in Arthropods -- NADPH Oxidases in Zebrafish -- Part VI. Structure -- Structural Insights into the Mechanism of DUOX1-DUOXA1 Complex -- Structure, Function and Mechanism of Six-Transmembrane Epithelial Antigen of the Prostate (STEAP) Enzymes -- Part VII. Pathology -- Chronic Granulomatous Disease -- Definitive Treatments for Chronic Granulomatous Disease with a Focus on Gene Therapy -- Part VIII. Future -- Quo Vadis NADPH Oxidases: Perspectives on Clinical Translation.

Description / Table of Contents: Chapter 1: Biochemistry of hyaluronan synthesis -- Chapter 2: Update on hyaluronan in development -- Chapter 3: Long non-coding RNAs and epigenetic regulation of hyaluronan synthesis -- Chapter 4: The hyaluronan-rich zones of plasma membrane protrusions and extracellular vesicles -- Chapter 5: Hyaluronan in Kidney Fibrosis -- Chapter 6: Inter-α-inhibitor proteins: A review of structure and function -- Chapter 7: CD44: Does CD44v6 adversely impact the prognosis of cancer patients? -- Chapter 8: The pharmacokinetics and pharmacodynamics of 4-methylumbelliferone and its glucuronide metabolite in mice -- Chapter 9: The role of hyaluronan in skin wound healing -- Chapter 10: Sulfated hyaluronan: a novel player in cancer therapeutic and bioengineering approaches.

Description / Table of Contents: Chapter 1. Introduction -- Chapter Two. Theories and Models -- Chapter 3. The Structure of Macroecological Data -- Chapter 4. Structure and Dynamics of Geographic Ranges -- Chapter 5. The Macroecological Understanding of Ecological Niches -- Chapter 6. Richness and Diversity Patterns -- Chapter 7. Macroecological Assemblages -- Chapter 8. Patterns in Body Size -- Chapter 9. From Theoretical to Applied Macroecology -- Chapter 10. Concluding Remarks. .

Description / Table of Contents: Introduction -- Batch Processing Methods in ImageJ -- Python: Data Handling, Analysis and Plotting -- Building a Bioimage Analysis Workflow Using Deep Learning -- GPU-Accelerating ImageJ Macro Image Processing Workflows Using CLIJ -- How to Do the Deconstruction of Bioimage Analysis Workflows: A Case Study with SurfCut -- i.2.i. with the (Fruit) Fly: Quantifying Position Effect Variegation in Drosophila Melanogaster -- A MATLAB Pipeline for Spatiotemporal Quantification of Monolayer Cell Migration.

Description / Table of Contents: A historical and evolutionary view of tight junctions -- Tricellular tight junctions -- Mechanosensitivity of tight junctions -- Intracellular traffic and non-canonical roles of ZO-2 protein -- Impact of claudin-2 and occludin expression in inflammation disorders -- Tight junctions in the inflamed gut -- Intestinal barrier disruption by enteropathogenic Escherichia coli -- Tight junction barrier function regulation by microbiota -- Claudin-7 participation in cell-substrate adhesion, cell migration, salt balance in the renal collecting duct and gut cell renewal and differentiation -- Regulation of the alveolar epithelial barrier by claudin-5 -- Regulation of the blood-retinal barrier by occludin phosphorylation, norrin and sonic hedgehog signaling -- Transmigration of metastatic cells through the blood-brain barrier -- Endocytosis of tight junction proteins -- Regulated degradation of claudins. .

Description / Table of Contents: Part 1: Functions of Macropinocytosis -- Chapter 1: Functional Diversity of Macropinocytosis -- Chapter 2: Macropinocytosis and Cancer: From Tumor Stress to Signaling Pathways -- Chapter 3: The amoebal model for micropinocytosis -- Chapter 4: Extracellular ATP and macropinocytosis -- Chapter 5: Macropinocytosis and Cell Migration: Don't drink an drive -- Chapter 6: Macropinocytosis in phagocyte function and immunity -- Part 2: Signaling Mechanisms Driving Macropinocytosis -- Chapter 7: Roles of 3' Phosphoinositides in Macropinocytosis -- Chapter 8: Signaling pathways that regulate macropinocytosis in mammalian cells -- Chapter 9: Wnt, GSK3 and Macropinocytosis -- Chapter 10: Kras addiction promotes cancer cell adapation in harsh microenvironment through micropinocytosis -- Chapter 11: Kras-independent macropinocytosis in pancreatic cancer.

Description / Table of Contents: 1 General Introduction -- 2 Peace Ecology in the Anthropocene for Africa -- 3 Civil Society, Climate Change, Security Risks Management and Peacebuilding in the Anthropocene -- 4 Faith-based Organisations and Environmental Peace: Impact of Laudato Si’ and Its Relevance in the Anthropocene -- 5 Healing Nature and Creation in the Anthropocene: A Reflection on the Role of Religion -- 6 Empowering Women to Build Peace: A Case Study of Grace to Heal Trust in Lupane District -- 7 Peacebuilding through Indigenous Knowledge Systems: Lessons from Civil Society Organisations in Zimbabwe -- 8 Civil Society and Peacebuilding in the Kivu Provinces of the Democratic Republic of Congo -- 9 Zimbabwe’s National Peace and Reconciliation Commission and Civil Society: Partners in Peacebuilding? -- 10 Civil Society and Peacebuilding in the Democratic Republic of Congo: Opportunities, Challenges and Recommendations -- 11 Promoting Democratisation in DR Congo: The Case Study of Act for Transparent and Peaceful Elections -- 12 Civil Society Organisations and School Peace Clubs in South Africa: An Outcome Evaluation -- 13 The Challenges and Opportunities for Civil Society in Peacebuilding: Lessons from the Matabeleland Collective, Zimbabwe -- 14 The Role of Civil Society Participation in Social Cohesion Processes in KwaZulu-Natal, South Africa.-15 Building the Capacity of Civil Society Organisations in Nonviolent Campaigning: A Case Study from South Sudan -- 16 How Informal Peace Committees Complement Macro-infrastructures for Peace in Zimbabwe -- 17 Protecting and Nurturing Children Born from Rape in South Kivu Communities: A Challenge for Civil Society -- 18 Indigenous Peacebuilding Approaches and the Accountability of Former Child Soldiers: African Case Studies -- 19 Navigating Channels for Civil Society Participation in Conflict Prevention and Peace-Making in the African Peace & Security Architecture -- 20 Centre-periphery Relations Between Civil Society Organisations and External Funding Partners: A Case Study of South Kivu’s Peace and Development Agenda. .

Description / Table of Contents: Chapter 1. The hope and the hype in organoid technology in regenerative medicine (Badrul Hisham Yahaya) -- Chapter 2. Pluripotent stem cell derived and adult-tissue-derived organoid (Tiago G. Fernandes) -- Chapter 3. Generation of human organoid for 3D stem cell culture Hans Clevers -- Chapter 4. Organogenesis in a dish: Organ developmental study using organoid technology (Kursad Tuksen) -- Chapter 5. Disease modelling using patient-derived organoid (Narisorn Kitiyanant) -- Chapter 6. Tumor organoid as a model to study cancer microenvironment (Ahmad Faried) -- Chapter 7. Gene-editing in organoid to improve understanding of human disease (Yinming Liang) -- Chapter 8. Organoid culture as a good model to study lung development (Mitsuru Morimoto) -- Chapter 9. Organoid as good model for respiratory diseases (Badrul Hisham Yahaya).-Chapter 10. In vitro 3D model on reproductive system (Ruttachuk Rungsiwiwut) -- Chapter 11. Modelling of neuronal organoid: The way forward and challenges (Juntang Lin) -- Chapter 12. Generation of cardiac organoid in early heart organogenesis (Tan Jun Jie) -- Chapter 13. Neural Crest-Derived Stem Cells in organoid development for neurodegenerative disease modelling (Darius Widera) -- Chapter 14. Organoid for drug discovery and personalized treatment (Toshio Takahashi) -- Chapter 15. Ethical concern on patient-derived organoid (Phuc Van Pham).

Description / Table of Contents: Chap 1: Disturbance ecology: a guideline -- Chap 2: Definitions and quantifications -- Chap 3: Concepts -- Chap 4: Abiotic disturbances -- Chap 5: Biotic disturbances -- Chap 6: Anthropogenic disturbances -- Chap 7: Disturbances in global change -- Chap 8: Disturbances and management.

Description / Table of Contents: Molecular Mechanisms of SARS-CoV-2/COVID-19 Pathogenicity on the Central Nervous System: Bridging Experimental Probes to Clinical Evidence and Therapeutic Interventions -- The Probable Protective Effect of Photobiomodulation on the Inflammation of the Airway and Lung in COVID-19 Treatment: A Preclinical and Clinical Meta-Analysis -- Metabolomics Signatures of SARS-CoV-2 Infection -- Autophagic Mediators in Bone Marrow Niche Homeostasis -- Pluripotency Stemness and Cancer: More Questions than Answers -- In Vitro Culturing of Adult Stem Cells: The Importance of Serum and Atmospheric Oxygen -- Mouse Models of Asthma: Characteristics, Limitations and Future Perspectives on Clinical Translation -- From Cells to Organs: The Present and Future of Regenerative Medicine -- Tissue-Restricted Stem Cells as Starting Cell Source for Efficient Generation of Pluripotent Stem Cells: An Overview -- Molecular Mechanisms behind Persistent Presence of Parvovirus B19 in Human Dilated Myocardium.

Description / Table of Contents: Chapter 1. Mechanisms and biological roles of DNA methyltransferases and DNA methylation – from past achievements to future challenges -- Chapter 2.Bacterial DNA Methylation and Methylomes -- Chapter 3. ChapterDomain Structure of the Dnmt1, Dnmt3a, and Dnmt3b DNA Methyltransferases -- Chapter 4. Enzymology of Mammalian DNA Methyltransferases -- Chapter 5. Genetic Studies on Mammalian DNA Methyltransferase -- Chapter 6. Structure and Mechanism of Plant DNA Methyltransferases -- Chapter 7. DNA Methylation in Honey Bees and the Unresolved Questions in Insect Methylomics -- Chapter 8. N6-Methyladenine: A Conserved and Dynamic DNA Mark -- Chapter 9. Pathways of DNA Demethylation -- Chapter 10. Structure and Function of TET Enzymes -- Chapter 11.Proteins That Read DNA Methylation -- Chapter 12. Recent advances on DNA base flipping – a general mechanism for writing, reading, and erasing DNA modifications.-Chapter 13. The Role of DNA Methylation in Cancer -- Chapter 14. DNMTs and DNA damage -- Chapter 15. Role of DNMTs in brain -- Chapter 16. Current and Emerging Technologies for the Analysis of the Genome-Wide and Locus-Specific DNA Methylation Patterns.-Chapter 17. Inhibitors of DNA methylation -- Chapter 18. Rewriting DNA Methylation Signatures at Will: The Curable Genome Within Reach? -- Chapter 19. DNA Labeling Using DNA Methyltransferases.

Description / Table of Contents: Involvement of Endothelial Nitric Oxide Synthase in Cerebral Microcirculation and Oxygenation in Traumatic Brain Injury -- Imaging cerebral energy metabolism in healthy infants -- Changes in cerebral oxygenation and systemic physiology during a verbal fluency task: Differences between men and women -- Brain Tissue Conductivity in Focal Cerebral Ischemia -- Physical stress Attenuates Cognitive inhibition: An fNIRS Examination -- Changes in Prefrontal Cortical Oxygenation During Tilt Table Orthostatic Hypotension in Subarachnoid Haemorrhage Patients -- Effects of different optical properties of head tissues on near-infrared spectroscopy Using Monte Carlo Simulations -- Frontal cerebral oxygenation in humans at rest: A mirror symmetry in the correlation with cardiorespiratory activity -- Photomodulation of lymphatic delivery of bevacizumab to the brain: the role of singlet oxygen -- NIRS-based study of local cerebral oxygenation during transcranial direct current stimulation in patients with mild traumatic brain injury -- Postnatal Exposure to Brief Hypoxia Alters Brain VEGF Expression and Capillary Density in Adult Mice -- Impaired Cognitive Performance in Mice Exposed to Prolonged Hyperoxia -- Chronic Ketosis Modulates HIF1α-Mediated Inflammatory Response in Rat Brain -- Motor Imagery and Frontal Head Oxygenation: An fNIRS Study -- Non-invasive detection of persistent cortical hypoxia in Multiple Sclerosis using frequency domain near-infrared spectroscopy (fdNIRS) -- Evaluation of intraoperative end-tidal Carbon dioxide change relates to length hospitalization in peridiaphragmatic surgery: a pilot study -- Pulmonary Embolism in COVID-19 patients is not related to a worsening in tissue oxygenation -- Cardiovascular risk score and gas exchange in COVID-19 patients: no correlation -- Heme Oxygenase 1/ High Mobility Group Box 1 pathway may have a possible role in Covid-19 ARDS (Acute respiratory distress syndrome): a pilot histological study -- Silent Hypoxemia in COVID-19 pneumonia -- Low Flow and Microvascular Shunts: A Final Common Pathway to Cerebrovascular Disease: A Working Hypothesis -- A case of intracranial vertebral artery stenosis treated with percutaneous transluminal angioplasty and stenting guided by brain oximetry -- Assessment of Optimal Arterial Pressure with Near-Infrared Spectroscopy in Traumatic Brain Injury Patients -- Effects of exercise-diet therapy on cognitive function in healthy elderly people evaluated by deep learning based on basic blood test data -- NIRS studies show reduced interhemispheric functional connectivity in individuals with Multiple Sclerosis that exhibit cortical hypoxia -- Eye Tracking Parameters Correlate With the Level of Cerebral Oxygen Saturation in Mild Traumatic Brain Injury: A Preliminary Study -- Critical closing pressure of cerebral circulation at concomitant moderate-to-severe traumatic brain injury -- Hybrid convolutional neural network (hCNN) for image reconstruction in near-infrared optical tomography -- Cross-frequency coupling between brain and body biosignals: A systemic physiology augmented functional near-infrared spectroscopy hyperscanning study -- Machine learning distinguishes familiar from unfamiliar pairs of subjects performing an eye contact task: A systemic physiology augmented functional near-infrared spectroscopy hyperscanning study -- Assessing Neurovascular Coupling Using Wavelet Coherence in Neonates With Asphyxia -- Basic examination of hemoglobin phase of oxygenation and deoxygenation in resting state and task periods in adults using fNIRS -- Development and validation of robust and cost-effective liquid heterogeneous phantom for time domain near-infrared optical tomography -- Effect of Exercise Therapy on Stress Response Evaluated by IoMT Monitoring System -- Improved optical tissue model for tissue oximetry imaging applications -- In vitro validation of a new tissue oximeter using visible light -- Photon and Proton Dose Painting based on Oxygen Distribution – Feasibility Study and Tumour Control Probability Assessment -- Effect of Acidosis-Induced Signalling Pathways on Mitochondrial O2 Consumption of Tumour Cells -- Feasibility of non-invasive measurement of tumor NAD(H) by in vivo phosphorus-31 magnetic resonance spectroscopy -- Acidosis-induced regulation of Egr1 and Ccn1 in vitro and in experimental tumors in vivo -- Perfusion-Limited Hypoxia Determines the Outcome of Radiation Therapy of Hypoxic Tumours -- Improved Oxygenation of Human Skin, Subcutis and Superficial Cancers upon Mild Hyperthermia Delivered by wIRA-Irradiation -- Blood Supply and Oxygenation Status of the Liver: From Physiology to Malignancy -- Optical Redox Imaging Is Responsive to TGFβ Receptor Signaling in Triple-Negative Breast Cancer Cells -- Evaluation of betulinic acid derivatives as PET tracers for hypoxia-induced carbonic anhydrase IX (CA IX) expression -- Role of the mTOR signaling pathway during extracellular acidosis in tumor cells -- Feasibility Study of Remote Contactless Perfusion Imaging with Consumer-Grade Mobile Camera -- Stability of a Novel PEGylation site on a Putative Hemoglobin Based Oxygen Carrier -- Oxygen storage in stacked phospholipid membranes under an oxygen gradient as a model for myelin sheaths -- Confocal laser and electron microscopic investigation of gap junctions in anaplastic astrocytomas -- A radiation biological analysis of the oxygen effect as a possible mechanism in FLASH -- Assessment of nicotinamide adenine dinucleotide in human tissues by in vivo phosphorus-31 magnetic resonance spectroscopic imaging at 1.5 Tesla -- Drag-Reducing Polymers Improve Vascular Hemodynamics and Tissue Oxygen Supply in Mouse Model of Diabetes Mellitus -- Hemorheologic Enhancement of Cerebral Perfusion increases oxygen supply and reduces Ab plaques deposition in a mouse model of Alzheimer’s Disease -- Calorimetric Characterization of the Binding Reaction Between Human Ferric Hemoglobins and Haptoglobin to Develop a Drug for Removal of Cell-Free Haemoglobin -- Feasibility To Measure Tissue Oxygen Saturation Using Textile-integrated Polymer Optical Fibers -- Effect of Atorvastatin on Microcirculation Evaluated by Vascular Occlusion Test with Peripheral Near lnfrared Spectroscop -- Flow characteristics of the conjugate of anti-CD3 monoclonal antibodies and magnetic nanoparticle in the PBS and the blood vessel -- Cerebrovascular Reserve (CVR) and Stages of Hemodynamic Compromise -- On the mechanism of sustained mitochondrial membrane potential without functioning complex IV -- Further evidence that gradients of extracellular pH direct migration of MDA-MB-231 cells in vitro -- Blood Flow and Respiratory Gas Exchange in the Human Placenta at Term: A Data Update -- Oxyhaemoglobin Level Measured Using Near-Infrared Spectrometer is Associated with Brain Mitochondrial Dysfunction After Cardiac Arrest in Rats -- Changes in Oxygenation Levels During Moderate Altitude Simulation (Hypoxia-Induced): A Pilot Study Investigating the Impact of Skin Pigmentation in Pulse Oximetry -- The Intramuscular Circulation is Affected by Neck and Shoulder Pain -- Intramuscular circulation of the lumbar multifidus in different trunk positions on standing -- Numerical Optimization of a NIRS Device for Monitoring Tissue Oxygen Saturation -- Upper trapezius muscle tonicity, assessed by palpation, relates to change in tissue oxygenation and structure as measured by Time-Domain Near Infrared Spectroscopy -- Perceived exertion correlates with multiple physiological parameters during cardiopulmonary exercise testing -- Systemic and Quadriceps Muscle O2 Dynamics in Subjects without Attenuation Point of Deoxygenated Hemoglobin Concentration during Ramp Cycling Exercise -- Jaw-Clenching Intensity Effects on Masseter Oxygen Dynamics and Fatigue: A NIRS Oximetry Study. .

Description / Table of Contents: 1.Challenges of Stem Cell Therapies for the Treatment of Infertility in Reproductive Medicine -- 2.Regeneration of Human Ovaries Through Mesenchymal Stem Cell Transplantation Is Becoming a Reality -- 3.In Vitro Activation of Follicles for Treatment of Ovarian Insufficiency -- 4.Ovarian Cancer Stem Cells and their Regulatory Mechanisms: Potential Targets -- 5.Ovarian Cancer Stem Cells: Approach to Individualized Medicine -- 6.New Insights in Spermatogonial Stem Cells -- 7.Spermatogonial Stem Cell Cryopreservation for Fertility Preservation -- 8.Endometrial Stem Cells and Endometriosis -- 9.Pathogenesis of Endometriosis: Are Endometrial Stem/Progenitor Cells Involved? -- 10.Stem Cell Transplantation for Endometrial Regeneration in Humans -- 11.Germinal Origin of Very Small Embryonic-like Stem Cells (VSELs): Relation to Primordial Germ Cells -- 12.The Role of Very Small Embryonic-like Stem Cells (VSELs) in Reproductive Tissues -- 13.Amniotic Membrane: A Unique Combination of Stem-Like Cells and Extracellular Matrix with Indispensable Potential for Regenerative Medicine -- 14.Human Umbilical Cord Blood Mesenchymal Stem Cell Transplantation in Kidney Injury Animal Models: a Critical Review -- 15.Stem Cells in Human Breast Milk and Neonate.

Description / Table of Contents: Chapter 1. General Principles -- Chapter 2. Signals – Scattering -- Chapter 3. Signals - Fluorescence, Phosphorescence, Impedance, Extinction -- Chapter 4. Fluidics -- Chapter 5. Light Sources -- Chapter 6. Optical Benches -- Chapter 7. Detectors and Electronics -- Chapter 8. Signal Analysis -- Chapter 9. The Cytometric File -- Chapter 10. Data Transformation -- Chapter 11. Data Representation -- Chapter 12. Data Analysis -- Chapter 13. Standards, Setup, Calibration, and Control Techniques -- Chapter 14. Fluorochromes – Overview -- Chapter 15. Fluorochromes Suitable for Antibody Conjugation -- Chapter 16. Fluorochromes That Bind Nucleic Acids -- Chapter 17. Fluorochromes for the Study of the Cell Features -- Chapter 18. Fluorescent Proteins -- Chapter 19. Spillover and Compensation -- Chapter 20. Artifacts -- Chapter 21. Cell Sorting -- Chapter 22. Non-Conventional Flow Cytometry -- Chapter 23. Statistics: A Cytometric Point of View.

Description / Table of Contents: Part I: Conceptualizing human-nature interactions -- Chapter 1. Conceptualizing human-nature interactions – an overview -- Chapter 2. Environmental Values and Nature’s Contributions to People: Towards methodological pluralism in evaluation of sustainable ecosystem services -- Chapter 3. Disentangling trade-offs between the state of coastal ecosystems with human well-being and activities as a strategy addressing sustainable tourism -- Chapter 4. From human-nature dualism towards more integration in socio-ecosystems studies -- Chapter 5. A network approach to Green Infrastructure: how to enhance ecosystem services provision? -- Chapter 6. Transformations of urban coastal nature(s): Meanings and paradoxes of Blue Urbanism and nature-based solutions for climate adaptation in Southeast Asia -- Part II: Mountain systems -- Chapter 7. Values of mountain landscapes: Insights about the Blue Mountains National Park, Australia from Twitter -- Chapter 8. Earth observations of human-nature interactions from a cultural ecosystem service perspective -- Chapter 9. Gendered Values, Roles, and Challenges for Sustainable Provision of Forest-based Ecosystem Services in Nepal -- Chapter 10. Environmental [in]equity: Accessibility to green spaces in a rapidly urbanizing mountain-city -- Chapter 11. Ecosystem services and sustainable development in the European Alps: spatial patterns and mountain-lowland relationships -- Chapter 12. Human-nature relationships for the Flathead Wild and Scenic River System: Analyzing diversity, synergies, and tensions in a mountainous region of Montana, USA -- Chapter 13. Resilience and sustainability of the Maloti-Drakensberg mountain system: a case study on the upper uThukela catchment -- Chapter 14. Invasive alien plants in the montane areas of South Africa: impacts and management options -- Part III: Urban systems -- Chapter 15. Ecosystem service flows across the rural-urban spectrum -- Chapter 16. A typology for green infrastructure planning to enhance multifunctionality incorporating peri-urban agricultural land -- Chapter 17. Urban green spaces in a post-apartheid city: challenges and opportunities for nature-based solutions -- Chapter 18. Green infrastructure and ecosystem services within spatial structure of city – examples from Poznań, Poland -- Chapter 19. Accessibility to and fragmentation of urban green infrastructure: importance for adaptation to climate change -- Chapter 20. Social Demand for Urban Wilderness in Purgatory -- Chapter 21. The Role of Allotment Gardens for Connecting Nature and People -- Chapter 22. Green spaces and their social functions: specific challenges in urban spaces of arrival -- Chapter 23. The link between urban green space planning tools and distributive, procedural and recognition justice -- Part IV: Coastal-marine systems -- Chapter 24. Can local knowledge of Small-scale fishers be used to monitor and assess changes in marine ecosystems in a European context? -- Chapter 25. Marine ecological democracy: participatory marine planning in Indigenous marine areas in Chile -- Chapter 26. The Socio-Ecological Dimension of Ocean Multi-Use -- Chapter 27. Localizing the Sustainable Development Goals for marine and coastal management in Norway: A venture overdue -- Chapter 28. Coastal-Marine ecosystem accounting to support Integrated Coastal Zone Management -- Chapter 29. Exposure of coastal ecosystem services to natural hazards in the Bangladesh coast -- Chapter 30. Adaptations to climate variability in fisheries and aquaculture social-ecological systems in the Northern Humboldt Current Ecosystem: challenges and solutions -- Chapter 31. Socio-Ecological transformations in coastal wetlands: an approach from the south-central zone of Chile -- Chapter 32. A Nature-based Solution for coastal foredune restoration: The Case Study of Maghery, County Donegal, Ireland.

Description / Table of Contents: Epithelial Stem Cells: Making, Shaping and Breaking the Niche -- Parathyroid Cell Differentiation from Progenitor Cells and Stem Cells: Development, Molecular Mechanism, Function, and Tissue Engineering -- Regenerative Medicine Application of Mesenchymal Stem -- Identification of Small Molecules That Enhance the Expansion of Mesenchymal Stem Cells Originating from Bone Marrow -- Human-Induced Pluripotent Stem Cell-Based Models for Studying Sex-Specific Differences in Neurodegenerative Diseases -- Current Status, Barriers, and Future Directions for Humanized Mouse Models to Evaluate Stem Cell-Based Islet Cell Transplant -- Mesenchymal Stem Cell Therapy for Osteoarthritis: Practice and Possible Promises -- The Historical Relationship Between Meis1 and Leukemia -- An Overview of Zebrafish Modeling Methods in Drug Discovery and Development -- Cellular Stress Responses in Oocytes: Molecular Changes and Clinical Implications.

Description / Table of Contents: Part 1. Regulatory.-1. Regulation of Cell Therapy in the United States.-2. Regulatory Landscape and Emerging Trends In Advanced Therapies Manufacturing: An EU Perspective.-3. Australian Cellular Therapy Regulations -- 4. Landscape for Regenerative Medicine Manufacturing in Japan -- 5. GLP Regulations for Non-clinical studies -- 6. Ethical Considerations in Cell Therapy -- 7. Investigational New Drug Applications for Cell Therapy Products -- 8. FDA Inspections -- 9. Commercialization of Investigational Cell Therapy Products -- Part 2 Quality Systems -- 10. The Meaning of Quality -- 11. Development and Maintenance of a Quality Program -- 12. Quality Control of Cellular Therapy Products and Viral Vectors -- 13. Quality Management Software – Q-Pulse -- 14. Selection of Contract Manufacturing and Testing Organizations -- Part 3 Facility Design -- 15. Introduction: Facility Design -- 16. PACT CPFs - Examples Describing Different Cell Processing Facility Designs -- 17. Design and Operation of a Multiuse GMP Facility at the City of Hope -- 18. Design and Operation of a Multiuse GMP Facility at the University of Miami -- 19. Design of a New Academic GMP Facility for Today and Beyond at the Dana-Farber Cancer Institute -- 20. Design and Licensure of an American Cord Blood Bank -- 21. Indiana University Vector Production Facility (IUVPF) -- 22. Qualification and Commissioning of a New GMP Facility -- Part 4 Facility Infrastructure -- 23. Environmental Monitoring -- 24. GMP Facility Cleaning and Maintenance -- 25. GMP Documentation -- 26. Process Validation -- 27. Equipment Qualification -- 28. Vendor Qualification and Supply Management -- 29. Staffing, Training and Competency -- Part 5 Product Management -- 30. Product Accessioning, Tracing and Tracking -- 31. ISBT 128 in Labeling of Cellular Therapy Products -- 32. Product Processing, Manufacturing and Administration -- 33. Transport and Shipment of Cellular and Gene Therapy Products -- 34. Regenerative Medicine: The Newest Cellular Therapy -- 35. Cellular Therapy Applications for COVID-19 -- Part 6 Professional Standards and Support Organizations -- 36. Professional Standards for Cellular Therapy: The Foundation for the Accreditation of Cellular Therapy (FACT) -- 37. AABB Cell Therapy Standards -- 38. USP Standards for Cell-based Therapies -- 39. The Role of the National Institute of Standards Measurement Assurance for Cell Therapies -- 40. National Science Foundation Engineering Research Center for Cell Manufacturing Technologies (CMaT) -- 41. Financial Considerations for Academic GMP Facilities -- 42. Governmental Support Opportunities for Cellular & Gene Therapies in the United States.

Description / Table of Contents: C ontents -- Part 1. Theory -- To Understand Economics, Follow the Money: To Understand Ecosystems, Follow the Energy -- Two Views of Ecology, Evolution, and Conservation -- Why I Wrote this Book -- Dualities Still Impede Conservation Efforts -- The Intergovernmental Science-Policy Platform of Biodiversity -- Targets for Conservation -- Evolving Objectives -- Literature Review -- Updating Ecosystem Ecology -- References -- What Can We Learn by Studying Ecosystems that We Can’t Learn from Studying Populations? -- The Predator-Prey Conundrum -- The Serengeti Ecosystem -- Evolution in the “Ecological Theater” -- Predator-Prey Interactions Tell Only Part of the Story -- Evolution in the “Thermodynamic Theater” -- References -- A Thermodynamic Definition of Ecosystems -- Ecosystems in the 20th Century -- Cycling of Strontium-90 -- Cesium-137 in Food Chains -- Recycling of Isotopes in Norwegian Sheep -- Ecological Energetics -- Is it Time to Bury the Ecosystem Concept? -- A Thermodynamic Definition of Life -- A Thermodynamic Definition of Ecosystems -- The Phase Transition between Order and Chaos -- References -- Thermodynamic Characteristics of Ecosystems -- Equilibrium -- The Equilibrium Law -- Thermodynamic Equilibrium -- Open Thermodynamic Systems -- Ecosystems are Thermodynamically Open Non-Equilibrium Systems -- Work is Performed by Non-equilibrium Systems -- Advantage of a Thermodynamically Open System -- 4.3 Ecosystems are Entropic -- 4.4 Ecosystems are Cybernetic -- Cybernetic Systems -- Economic Systems are Cybernetic Ecosystems are Cybernetic -- The Ecosystem Feedback Function -- Indirect vs. Direct Feedback -- Deviation Dampening and Amplifying Feedback -- Set Points -- Ecosystems are Autocatalytic -- Ecosystems have Boundaries -- Ecosystems are Hierarchical -- Hierarchy in Physical Systems -- Hierarchy in Ecological Systems -- Common Currencies -- Macro-and Micro-System Models -- Why an Ecosystem Model that Includes Everything is not Possible -- A Nested Marine Community -- Ecosystems are Deterministic -- Ecosystems are Information Rich -- An Engineering Definition of Information -- Information to Facilitate Exchange -- High Energy Information -- Low Energy Information -- Information Theory -- Genetic Information -- Ecosystems are Non-Teleological -- Criticisms of Ecosystem Models -- References -- Ecosystem Control: A Top-Down View -- Two Ways to Look at Systems -- Composing and Decomposing Trophic Webs -- Decomposers in Soil Organic Matter -- Decomposers in Marshes and Mangroves -- Control of Systems -- Top-Down vs. Bottom-Up -- Top-Down Exogenous Control -- Exogenous Impacts and Stability -- Top-Down Endogenous Control -- Endogenous Control through Nutrient Recycling -- Autocatalysis -- Control of Microbial Activity -- Inhibition of Microbial Activity by Leaf Sclerophylly -- Inhibition of Microbial Activity Chemical Defenses -- Inhibition of Microbial Activity by Ecological Stoichiometry -- The Synchrony Principle -- The Decay Law -- Direct Nutrient Cycling -- The Role of Animals -- Indirect Interactions -- Marine Systems -- Nutrient and Energy Recycling -- Exogenous Control -- Control in Lakes -- Control in Managed Ecosystems -- References -- Ecosystem Control: A Bottom-Up View -- Species as Arbitrageurs of Energy -- Relation Between Rate of Flow and Mass in Hydraulic Systems -- Relation Between Population Biomass and Rate of Energy Flow -- Equilibrium -- Mechanisms of Adjustment -- Adjustments and Climate Change -- Bird Populations -- Dis-equilibrium -- Population Instability vs. Ecosystem Instability -- Control by Interactions: Direct vs. Indirect -- Indirect Interactions -- Direct Interactions -- Predator – Prey -- Mutualisms -- Competition -- Decomposition -- Parasitism and Disease -- Commensalism and Amensalism -- Persistence of Negative Interactions -- References -- Ecosystem Stability -- Background -- A Thermodynamic Definition -- Regime Shift -- Metastability -- Pulsed Stability -- Resistance and Resilience -- Species Richness and Functional Stability -- Species Richness and Cultural Values -- Keystone Species, and Population and Ecosystem Stability -- 7.5.1 Keystone Species in the Yellowstone region of Wyoming -- References -- 8. Case Studies of Ecosystem Control and Stability -- Walden -- “Harmony in Nature” -- Feedback Produces Nature’s “Harmony” -- Feedback Mechanisms -- Perturbations in Amazon Rain Forests -- Top-Down Control -- The San Carlos Project: A Small-scale, Low Intensity, Short Duration Disturbance -- 8.3.2 The Jarí Project: A Large-scale, High Intensity, Long Duration Disturbance -- Bottom-Up Control -- The El Verde Project -- The Long-Term Ecological Research Project in Puerto Rico -- The Lago Guri Island Project -- The Biological Dynamics of Tropical Rainforest Fragments Project -- What have Case Studies Taught us about Stability of Tropical Ecosystems? -- Tropical Ecosystems are Stable -- Tropical Ecosystems are Unstable -- Energy Flow in Tropical Savannas and Rain Forests -- Insects in Tropical Ecosystems -- Application of Lessons to Other Regions -- Relevance to Temperate Zones -- Relevance to Aquatic Ecosystems -- The Experimental Lakes Project (Ecosystem Control of Species) -- Lake Mendota Studies (Species Control of Ecosystems) -- 8.7 Case Studies as Tests of Thermodynamic Theory -- References -- Entropy and Maximum Power -- Entropy -- 9.2 Entropy in a Steel Bar -- Thermodynamic Equilibrium -- Entropic Gradients -- Capturing and Storing Entropy -- Evapotranspiration and Entropy Reduction -- Life is a Balance between Storing and Releasing Entropy -- The Law of Maximum Entropy Production -- Energy for Metabolism as well as Growth -- Unassisted Entropy Capture is a Unique Characteristic of Life.-9.6Entropy Storage by Ecosystems -- 9.6.1 What Causes Entropy to be Stored? -- 9.7 Capturing Pressure -- 9.8 Entropy and Time -- 9.8.1 Time’s Speed Regulator -- Efficiency of Energy Transformations -- Passage of Time for Cats -- 9.9The Maximum Power Principle.-9.10 Optimum Efficiencies for a Truck and its Driver.-9.11 Sustainability -- References -- A Thermodynamic View of Succession -- 10.1 The Population View -- 10.2 The Thermodynamic View -- 10.2.1 Leaf Area Index and Succession -- 10.2.2 Power Output as a Function of Leaf Area Index -- 10.2.3 What Causes Changes in Leaf Area Index? -- 10.2.4 Maximum Entropy Production Principle -- 10.2.5 Successional Ecosystems Move Further from Thermodynamic Equilibrium -- 10.2.6 Entropy Storage by Animals -- 10.3 The Strategy of Ecosystem Development -- A Problem with Odum’s Strategy -- Why Power Output Continues to Increase -- Revised Definition of Maximum Power -- Costs of Ecosystem Stabilization -- Transactional Costs -- Succession, Power Output, and Efficiency -- 10.5.1 Kleiber’s Law -- Are Ecosystems Spendthrifts? -- Interactions Between Species Facilitate Increase in Power Output -- Facilitation -- Tolerance -- Inhibition -- Intermediate Disturbance Hypothesis -- Nutrient Use Efficiency during Succession -- Succession Following Logging vs Following Agriculture -- 10.10 Thermodynamic View of Succession: Implications for Resource Management -- References -- Panarchy -- The Universal Cycle of Systems -- Panarchy -- Thermodynamic Interpretation of the Sacred Rules -- 11.2.1 Growth and Consolidation -- 11.2.2 Collapse -- Renewal -- Sub-systems -- Panarchy over 2 Billion Years of Evolution -- Consolidation, Bureaucracy and System Collapse -- Bureaucracy in Action (Case Studies) -- Case Study: Panarchy in the Georgia Piedmont -- Thermodynamic Interpretation -- References -- 12. A Thermodynamic View of Evolution -- 12.1 Life – A Physicist's View -- 12.1.1 Life is Produced by Capturing Entropy -- 12.1.2 The Origin of Life -- 12.2 Two Approaches to Evolution -- 12.2.1 The Eco-Evo-Devo View -- 12.2.2 The Thermodynamic View -- 12.2.3 Fitness -- 12.2.4 The “Goal” of Evolution -- 12.3 The Relationship between Species and Environment -- 12.3.1 Evolution’s “Theater” -- 12.3.2 Is Evolution Stochastic or Deterministic? -- 12.4 Ecosystem Evolution -- 12.4.1 Succession was the Clue -- 12.4.2 Ecosystems Moved away from Equilibrium -- 12.4.3 Thermodynamic Mechanisms -- 12.4.4 Biological Mechanisms -- 12.4.5 Ecosystem Fitness -- 12.4.6 Ecosystems Evolve One Step at a Time -- 12.5. The Origin of Ecosystems -- 12.5.1 Origin of Feedback Loops -- 12.5.2 Origin of Trophic Levels -- 12.5.3 Why are there Trophic Levels? -- 12.6 The “Goal” of Ecosystem Evolution -- 12.6.1 Conflicting Goals? -- 12.6.2 “Motivations” of Species -- 12.6.3 The Earth Ecosystem -- 12.6.4 Why is there Resistance to the Idea of Ecosystem Evolution? -- 12.6.5 Evolution of Economic Systems -- 12.7 A Thermodynamic Model of Ecosystem Evolution -- 12.7.1 Network Models -- 12.7.2 Increase in Complexity of Trophic Webs -- 12.7.3 Evolution of Trophic Webs -- 12.7.4 Life Moves Ashore -- 12.8 Biodiversity and the Five Great Extinctions -- 12.8.1 The Cretaceous-Tertiary (K-T) Boundary Extinction -- 12.8.2The Amazing Sustainability of Trophic Chains -- 12.8.3 A Test of Thermodynamic Theory -- 12.9 Panarchy and Evolution -- 12.10 Thermodynamic Requirements for Living Systems on Other Planets -- References -- -- Why is Species Diversity Higher in the Tropics? -- 13.1 Tropical Explorations -- 13.2 A Few Theories -- 13.3 A Thermodynamic Explanation -- 13.3.1 The Latitudinal Energy Gradient -- 13.3.2 The Latitudinal Productivity Gradient -- 13.3.3 The Data -- 13.3.4 Other Factors Affecting Productivity -- 13.4 Empirical Evidence for a High Productivity High Diversity Correlation -- 13.5 Humboldt’s Enigma -- 13.5.1 Are Productivity and Species Richness Correlated on Tropical -- Mountains? -- 13.6 The Mechanism Linking Productivity and Diversity -- 13.7 Answer to “Why is Species Diversity Higher in the Tropics?” -- 13.7.1 Differences within the Tropics -- 13.8 Why is Species Diversity Low at High Latitudes? -- 13.9 An Economic Perspective on D.

Description / Table of Contents: Introduction: Taxonomy, distribution and conservation status of wild guanaco’s populations -- 1. Zooarchaeological and socio-anthropological perspective of the human - guanaco (Lama guanicoe) interaction over the last 6000 years in the Patagonia, Argentina -- 2. Interspecific competition between guanacos and livestock and its impact on Patagonian rangelands: review and synthesis -- 3. Health status of Patagonian guanaco and its relevance for conservation -- 4. Patagonian pumas and their ungulate prey in the 21st century, a key interaction in a degraded environment -- 5. International policies and national legislation concerning guanaco conservation, management and trade in Argentina -- 6. Guanaco sustainable management as a conservation strategy and socioeconomic rural development -- 7. Historical perspective and current advances in ecology, conservation and management of the guanaco in the Chilean Patagonia -- 8. Lessons for the future of conservation and sustainable use of guanacos.

Description / Table of Contents: Part I: About Environmental Education -- Chapter 1 - Training and dissemination about the Environment: keys to impulse the abiotic component of Environmental Education -- Chapter 2 Educating to deliver environmentally focused social innovation -- Chapter 3 - Environmental education for sustainable development: working for fundamental rights -- Chapter 4 - Nature as a teaching resource and the nature of learning -- Part II: Environmental Education and it´s Teaching -- Chapter 5 - The importance of Nature-based solutions to enhance Cabo Verde's Environment -- Chapter 6- Development of Scientific Literacy and the impact of environmental attitudes of citizens in a geological natural space -- Chapter 7- A PBL approach to Environmental Education through a Field Trip and a Science Centre Visit -- Chapter 8- Living labs in higher education: sustainable buildings technologies -- Chapter 9 - What is doing Latin America regarding the teaching of Nature-based solutions to boost Environmental Education? -- Chapter 10 - Lessons learned from including aquaponic experiments into five different tertiary education curricula -- Chapter 11 - Recommendations for promoting Environmental Education through Nature-based solutions at Turkish Higher Education Institutes -- Part III: Environmental Education and Social Engagement -- Chapter 12 - Bees and Society: native biodiversity as a strategy for environmental education based on the processes of nature -- Chapter 13- Perceptions about Sustainable Development of visitants in an Environmental Education Natural Park -- Chapter 14 - Start Park project: co-designing green-blue infrastructures to build resilient communities to climate change -- Chapter 15 - Societal embedding in geoparks: a case study in Portugal -- Chapter 16 - Environmental Education in Naturtejo UNESCO Global Geopark (Portugal): a nature-based approach -- Part IV: – Environmental Education and Nature-Based Solutions -- Chapter 17- Green Roof and walls technology standardisation and market across Europe -- Chapter 18- How Nature-Based Solutions can Contribute to Enhance Circularity in Cities -- Chapter 19- Nature-based solutions to promote environmental education on integral ecological sanitation -- Chapter 20 - Nature-based solutions for environmental education in the East Asian context -- Chapter 21- Decarbonizing the European energy sector: frameworks, examples and how education plays a key role -- Chapter 22- Nature-based solutions for water pollution control: promoting environmental education through case studies.

Description / Table of Contents: Cell and Molecular Biology of Centrosome Structure and Function -- The centrosome Cycle within the cell cycle -- Centrosome as center for proteolytic activity and dysfunctions associated with pathogenesis of human disease -- Centrosome dysfunctions in cancer -- Virus exploitation of centrosomes -- Centrosomes in reproduction -- Transition from centrosomal to non-centrosomal microtubule organization during cellular polarization -- External and environmental effects on Centrosomes -- Centrosomes and centrosome equivalents in other systems -- Non-centrosomal microtubule organization in plant cells.

Description / Table of Contents: A Protein-centric Perspective of Autophagy and Apoptosis Signaling and Crosstalk in Health and Disease -- Adrenergic receptor signaling pathways in the regulation of apoptosis -- Apoptosis in Ischemic Heart Disease -- Autophagy in cardiac physiology and pathology -- Caspase signaling pathways as convenors of stress adaptation -- Cross talk between apoptosis and autophagy in regulating the progression of heart disease -- Fibroblasts, Fibrosis and Autophagy -- Gene Therapy and Its Application In Cardiac Diseases -- Inflammation and mitochondrial degradation in the heart -- Mitochondria and Cellular Hosts_An Uneasy Truce -- Mitochondrial Dysfunction and Mitophagy -- Proteotoxicity and Autophagy in Neurodegenerative and Cardiovascular Diseases -- Regulation of Cell Death Signaling Pathways in Cardiac Myocytes by Mitochondrial Bnip3 – Inna -- Role of Cardiomyocyte Apoptosis in Heart Failure -- The Role of FGF2 Isoforms In Cell Survival In The Heart.

Description / Table of Contents: PRELIMINARY (ToC of second edition) 1 Plant ecology at high elevations -- The concept of limitation -- A regional and historical account -- The challenge of alpine plant research -- 2 The alpine life zone -- Altitudinal boundaries -- Global alpine land area -- Alpine plant diversity -- Origin of alpine floras -- Alpine growth forms -- 3 Alpine climate -- Which alpine climate -- Common features of alpine climates -- Regional features of alpine climates -- 4 The climate plants experience -- Interactions of relief, wind and sun -- How alpine plants influence their climate -- The geographic variation of alpine climate -- 5 Life under snow: protection and limitation -- Temperatures under snow -- Solar radiation under snow -- Gas concentrations under snow -- Plant responses to snowpack -- 6 Alpine soils -- Physics of alpine soil formation -- The organic compound -- The interaction of organic and inorganic compounds -- 7 Alpine treelines -- About trees and lines -- Current altitudinal positions of climatic treelines -- Treeline-climate relationships -- Intrazonal variations and pantropical plateauing of alpine treelines -- Treelines in the past -- Attempts at a functional explanation of treelines -- A hypothesis for treeline formation -- Growth trends near treelines -- Evidence for sink limitation -- 8 Climatic stress -- Survival of low temperature extremes -- Avoidance and tolerance of low temperature extremes -- Heat stress in alpine plants -- Ultraviolet radiation — a stress factor -- 9 Water relations -- Ecosystem water balance -- Soil moisture at high altitudes -- Plant water relations — a brief review of principles -- Water relations of alpine plants -- Desiccation stress -- Water relations of special plant types -- 10 Mineral nutrition -- Soil nutrients -- The nutrient status of alpine plants -- Nutrient cycling and nutrient budgets -- Nitrogen fixation -- Mycorrhiza -- Responses of vegetation to variable nutrient supply -- 11 Uptake and loss of carbon -- Photosynthetic capacity of alpine plants -- Photosynthetic responses to the environment -- Daily carbon gain of leaves -- The seasonal carbon gain of leaves -- C4 and CAM photosynthesis at high altitudes -- Tissue respiration of alpine plants -- Ecosystem carbon balance -- 12 Carbon investments -- Non-structural carbohydrates -- Lipids and energy content -- Carbon costs of leaves and roots -- Whole plant carbon allocation -- 13 Growth dynamics and phenology -- Seasonal growth -- Diurnal leaf extension -- Rates of plant dry matter accumulation -- Functional duration of leaves and roots -- 14 Cell division and tissue formation -- Cell size and plant size -- Mitosis and the cell cycle -- From meristem activity to growth control -- 15 Plant biomass production -- The structure of alpine plant canopies -- Primary productivity of alpine vegetation -- Plant dry matter pools -- Biomass losses through herbivores -- 16 Plant reproduction -- Flowering and pollination -- Seed development and seed size -- Germination -- Alpine seed banks and natural recruitment -- Clonal propagation -- Alpine plant age -- Community processes -- 17 Global change at high elevation -- Alpine land use -- The impact of altered atmospheric chemistry -- Climatic change and alpine ecosystems -- References (with chapter annotation) -- Taxonomic index (genera) -- Geographical index -- Color plates -- Plant life forms -- The alpine life zone -- Environmental stress -- The human dimension.

Description / Table of Contents: Part 1: Historical and biogeographical aspects -- The Atlantic Forest: an introduction to the megadiverse forest of Southern America -- The Atlantic Forest Ecological History: from pre-history to the Anthropocene -- The North-eastern Atlantic Forest: biogeographical, historical and current aspects in the Sugarcane Zone -- The Hileia Baiana - an assessment of natural and historical aspects of the land use and degradation of the central corridor of the Brazilian Atlantic Forest -- The southern Atlantic Forest: Use, degradation, and perspectives for conservation -- Part II – Biodiversity -- Tree diversity in the Brazilian Atlantic Forest: biases and general patterns using different sources of information -- Vascular Epiphytes of the Atlantic Forest: diversity and community ecology -- Social Insects of the Atlantic Forest -- Tetrapod diversity in the Atlantic Forest: maps and gaps -- Freshwater Studies in Atlantic Forest: general overview and prospects -- Part III – Threats -- Land-cover changes and an uncertain future: will the Brazilian Atlantic Forest lose the chance to become a hopespot? -- Climate change and biodiversity in the Atlantic Forest: best climatic models, predicted changes and impacts, and adaptation options -- Non-native species introductions, invasions, and biotic homogenization in the Atlantic Forest -- Causes and consequences of large-scale defaunation in the Atlantic forest -- Pollination systems in the Atlantic Forest: characterization, threats, and opportunities -- IV - Opportunities -- Atlantic Forest: ecosystem services linking people and biodiversity -- Changing the agriculture paradigm in the Brazilian Atlantic Forest: the importance of agroforestry -- Engaging people for large-scale forest restoration: Governance lessons from the Atlantic Forest of Brazil -- The Atlantic Forest Trail: connecting people, biodiversity and protected areas -- Conservation initiatives in the Brazilian Atlantic forest -- Financing conservation in the Brazilian Atlantic Forest -- Integrating researchers for understanding the biodiversity in Atlantic Forest -- The future of the Atlantic Forest.

Description / Table of Contents: Chapter 1. Introduction (Deborah C. Hayes, Becky K. Kerns, Toral Patel-Weynand, and Deborah M. Finch) -- Chapter 2. Impacts of Invasive Species in Terrestrial and Aquatic Systems in the United States (Albert E. Mayfield III, Steven J. Seybold, Wendell R. Haag, M. Tracy Johnson, Becky K. Kerns, John C. Kilgo, Daniel J. Larkin, Rima D. Lucardi, Bruce D. Moltzan, Dean E. Pearson, John D. Rothlisberger, Jeffrey D. Schardt, Michael K. Schwartz, and Michael K. Young) -- Chapter 3. Impacts of Invasive Species on Forest and Grassland Ecosystem Processes in the United States (Chelcy Ford Miniat, Jennifer M. Fraterrigo, Steven T. Brantley, Mac A. Callaham, Jr., Susan Cordell, Jeffrey S. Dukes, Christian P. Giardina, Shibu Jose, and Gary Lovett) -- Chapter 4. Effects of Climate Change on Invasive Species (Deborah M. Finch, Jack L. Butler, Justin B. Runyon, Christopher J. Fettig, Francis F. Kilkenny, Shibu Jose, Susan J. Frankel, Samuel A. Cushman, Richard C. Cobb, Jeffrey S. Dukes, Jeffrey A. Hicke, and Sybill K. Amelon) -- Chapter 5. Invasive Species Response to Natural and Anthropogenic Disturbance (Susan E. Meyer, Mac A. Callaham, Jr., Jane E. Stewart, and Steven D. Warren) -- Chapter 6. Early Intervention Strategies for Invasive Species Management: Connections Between Risk Assessment, Prevention Efforts, Eradication, and Other Rapid Responses (Robert C. Venette, Doria R. Gordon, Jennifer Juzwik, Frank H. Koch, Andrew M. Liebhold, Robert K.D. Peterson, Sharlene E. Sing, and Denys Yemshanov) -- Chapter 7. Management of Landscapes for Established Invasive Species (Therese M. Poland, Jennifer Juzwik, Allen Rowley, Cynthia D. Huebner, John C. Kilgo, Vanessa M. Lopez, Deanna H. Olson, Dean Pearson, Robert Progar, Robert Rabaglia, John D. Rothlisberger, Justin B. Runyon, and Sharlene E. Sing) -- Chapter 8. Restoration of Landscapes and Habitats Affected by Established Invasive Species (Jennifer Koch, Dean E. Pearson, Cynthia D. Huebner, Michael K. Young, and Richard A. Sniezko) -- Chapter 9. Sectoral Impacts of Invasive Species in the United States and Approaches to Management (Anne S. Marsh, Deborah C. Hayes, Patrice N. Klein, Nicole Zimmerman, Alison Dalsimer, Douglas A. Burkett, Cynthia D. Huebner, Robert Rabaglia, Laura A. Meyerson, Bonnie L. Harper-Lore, Jamie L. Davidson, Marla R. Emery, Travis Warziniack, Rebecca Flitcroft, Becky K. Kerns, and Vanessa M. Lopez) -- Chapter 10. Inventory and Monitoring of Invasive Species (Sonja Oswalt, Chris Oswalt, Alycia Crall, Robert Rabaglia, Michael Schwartz, and Becky K. Kerns) -- Chapter 11. Tools and Technologies for Quantifying Spread and Impacts of Invasive Species (Matt Reeves, Inés Ibáñez, Dana Blumenthal, Gang Chen, Qinfeng Guo, Catherine Jarnevich, Jennifer Koch, Frank Sapio, Michael K. Schwartz, Bruce K. Wylie, and Stephen Boyte) -- Chapter 12. Social and Cultural Dynamics of Non-Native Invasive Species (John Schelhas, Janice Alexander, Mark Brunson, Tommy Cabe, Alycia Crall, Michael J. Dockry, Marla R. Emery, Susan J. Frankel, Nina Hapner, Caleb R. Hickman, Rebecca Jordan, Michael J. LaVoie, Zhao Ma, Ross K. Meentemeyer, Joe Starinchak, and Jelena Vukomanovic) -- Chapter 13. The Role of International Cooperation in Invasive Species Research (Andrew Liebhold, Faith Campbell, Doria R. Gordon, Qinfeng Guo, Nathan Havill, Bradley Kinder, Richard MacKenzie, David R. Lance, Dean Pearson, Sharlene E. Sing, Travis Warziniack, Robert C. Venette, and Denys Yemshanov) -- Chapter 14. Economics of Invasive Species (Travis Warziniack, Robert G. Haight, Denys Yemshanov, Jenny L. Apriesnig, Thomas P. Holmes, Amanda M. Countryman, John D. Rothlisberger, and Christopher Haberland) -- Chapter 15. Legislation and Policy (Faith T. Campbell, Hilda Diaz-Soltero, and Deborah C. Hayes) -- Chapter 16. Future Invasive Species Research Challenges and Opportunities (Becky K. Kerns, Therese M. Poland, Robert C. Venette, Toral Patel-Weynand, Deborah M. Finch, Allen Rowley, Deborah C. Hayes, Mike Ielmini) -- APPENDIX 1: Regional Summaries.

Description / Table of Contents: Part I. Soil and Sediment Contaminants, Risk Assessment and Remediation -- Chapter 1. Introduction to Part I: Soil and Sediment Contaminants, Risk Assessment and Remediation -- Chapter 2. Combating Arsenic Pollution in Soil Environment via Alternate Agricultural Land Use -- Chapter 3. Temporal and Seasonal Variation in Leachate Pollution Index (LPI) in Sanitary Landfill Sites- A Case study of Baidyabati landfill, West Bengal, India -- Chapter 4.Quantification of Landfill Gas Emission and Energy Recovery Potential: A Comparative Assessment of LandGEM and MTM Model for Kolkata -- Chapter 5. Assessment of natural enrichment of heavy minerals along coastal placers of India: Role of lake and river mouth embayment and its implications -- Chapter 6. Assessment the Impact of Plastic Contaminated Fertilizers on Agricultural Soil Health: A Case Study in Memari II C.D.Block, Purba Bardhaman,West Bengal, India -- Chapter 7. Determining the Role of Leaf Relative Water Content and Soil Cation Exchange Capacity in Phytoextraction Process – Using Regression Modelling -- Chapter 8. Phytoremediation of Arsenic using Allium sativum as Model System -- Chapter 9. Spatio-temporal analysis of open waste dumping sites using Google Earth: A case study of Kharagpur City, India -- Part II. Water Contaminants, Risk Assessment and Remediation -- Chapter 10. Introduction to Part II: Water Contaminants, Risk Assessment and Remediation -- Chapter 11. Groundwater Arsenic Contamination Zone based on geospatial modeling, risk and remediation -- Chapter 12. Geospatial assessment of surface water pollution and industrial activities in Ibadan, Nigeria -- Chapter 13. Aquaculture-based water quality assessment and risk remediationalong the Rasulpur River belt, West Bengal -- Chapter 14. Heavy Metal Contamination in Groundwater and Impact on Plant and Human -- Chapter 15. Emerging Threats of Microplastic contaminant in freshwater environment -- Chapter 16. Exploring Particle Size Transport Variability of Suspended Sediments in two Alpine Catchments over the Lesser Himalayan Region, India -- Chapter 17. Salinity and corrosion potential of groundwater in Mewat district of Haryana, India -- Chapter 18. Threats to quality in the coasts of the Black Sea: heavy metal pollution of seawater, sediment, macro-algae and sea-grass -- Chapter 19. Geospatial assessment of groundwater quality for drinking through Water Quality Index and Human Health Risk Index in an upland area of Chotanagpur Plateau of West Bengal, India -- Chapter 20. Existence of Pharmaceuticals and Personal Care Products (PPCPs) in the conventional water treatment process -- Chapter 21. Arsenic-rich surface and groundwater around eastern parts of Rupnagar district, Punjab, India -- Part III. Environmental Contaminants, Impacts and Sustainable Management -- Chapter 22. Introduction to Part III: Environmental Contaminants, Risk Assessment and Remediation -- Chapter 23. Dynamics of ultra-fine particles in indoor and outdoor environments: a modelling approach to study the evolution of particle characteristics -- Chapter 24. Environmental impacts of coal-mining and coal-fired power-plant activities in a developing country with global context -- Chapter 25. Overview of Indoor air pollution: A human health perspective -- Chapter 26. Mineralogy and Morphological characterization of Technogenic Magnetic Particles (TMP) from industrial dust: Insights into environmental implications -- Chapter 27. Pesticides: Recent Updates on Types Toxicity and Bioremediation Strategies -- Chapter 28. Commonly available plant neem (Azadirachtaindica A. Juss) ameliorates dimethoate induced toxicity in climbing perch Anabas testudineus -- Chapter 29. Estimating Particulate Matter concentrations from MODIS AOD considering meteorological parameters using Random Forest Algorithm -- Chapter 30 Bio-monitoring and bioremediation of a trans-boundary river in India: Functional roles of benthic mollusks and fungi -- Chapter 31 Assessing the Maximum Aerobic Biodegradation Potential of Leaf Litter, an Organic Fraction of Municipal Solid Waste, Under Optimum Nutrient Conditions -- Chapter 32. Rising trend of air pollution and its decadal consequences on meteorology and thermal comfort over Gangetic West Bengal, India.

Description / Table of Contents: Chapter 1. Introduction to Fire Ecology across USA Forested Ecosystems: Past, Present, and Future (Cathryn H. Greenberg, Beverly S. Collins, Scott Goodrick, Michael C. Stambaugh, and Gary R. Wein) -- Chapter 2. The Role of Fire in the Dynamics of Piedmont Vegetation (Joanna Spooner, Robert K. Peet, Michael P. Schafale, Alan S. Weakley and Thomas R. Wentworth) -- Chapter 3. Fire Ecology and Fire Management of Southeastern Coastal Plain Pine Ecosystems (Jeff S. Glitzenstein, J. Stephen Brewer, Ronald. E. Masters, J. Morgan Varner, and J. Kevin Hiers) -- Chapter 4. Fire Ecology and Management in Eastern Broadleaf and Appalachian Forests (Mary A. Arthur, J. Morgan Varner, Charles W. Lafon, Heather D. Alexander, Daniel C. Dey, Craig A. Harper, Sally P. Horn, Todd F. Hutchinson, Tara L. Keyser, Marcus A. Lashley, Christopher E. Moorman, and Callie J. Schweitzer) -- Chapter 5. Fire Ecology and Management of Forest Ecosystems in the Western Central Hardwoods and Prairie-Forest Border (Michael C. Stambaugh, Benjamin O. Knapp, and Daniel C. Dey) -- Chapter 6. Fire in Floodplain Forests of the Southeastern USA hy (Paul R. Gagnon, Loretta L. Battaglia, Brice B. Hanberry, William H. Conner, and Sammy L. King) -- Chapter 7. History and Future of Fire in Hardwood and Conifer Forests of the Great Lakes-Northeastern Forest Region, USA(Lee E. Frelich, Craig G. Lorimer, and Michael C. Stambaugh) -- Chapter 8. Fire Ecology of Rocky Mountain Forests(Sharon M. Hood, Brian J. Harvey, Paula J. Fornwalt, Cameron E. Naficy, Winslow D. Hansen, Kimberley T. Davis, Mike A. Battaglia, Camille Stevens-Rumann, Victoria Saab) -- Chapter 9. Fire Ecology of the North American Mediterranean-Climate Zone(Hugh D. Safford, Ramona J. Butz, Gabrielle N. Bohlman, Michelle Coppoletta, Becky L. Estes, Shana E. Gross, Kyle E. Merriam, Marc D. Meyer, Nicole A. Molinari, and Amarina Wuenschel) -- Chapter 10. Fire Ecology and Management in Pacific Northwest Forests(Matthew J. Reilly, Jessica E. Halofsky, Meg A. Krawchuk, Daniel C. Donato, Paul F. Hessburg, James Johnston, Andrew Merschel, Mark E. Swanson, Joshua S. Halofsky, and Thomas A. Spies) -- Chapter 11. Fire Ecology and Management of Southwestern Forests(Peter Z. Fulé, Catrin M. Edgeley, Carol L. Chambers, Serra Hoagland, Blanca Céspedes) -- Chapter 12. Fire and Forests in the 21st Century: Managing Resilience under Changing Climates and Fire Regimes in USA Forests(James M. Vose, David L. Peterson, Christopher J. Fettig, Jessica E. Halofsky, J. Kevin Hiers, Robert E. Keane, Rachel Loehman, and Michael C. Stambaugh).

Description / Table of Contents: Part 1 Introduction -- 1 Host Community Interfaces: The Wildlife-Livestock -- 2 Natural And Historical Overview Of The Animal Wildlife-Livestock Interface -- 3 The Ecology Of Pathogens Transmission At The Wildlife-Livestock Interface: Beyond Disease Ecology, Towards Socio-Ecological System Health -- Part 2 Regional Perspectives Of Disease At The Wildlife-Livestock Interface -- 4 Characteristics And Perspectives Of Disease At The Wildlife-Livestock Interface In Europe -- 5 Characteristics And Perspectives Of Disease At The Wildlife-Livestock Interface In Asia -- 6 Characteristics And Perspectives Of Disease At Wildlife-Livestock Interface In Africa -- 7 Characteristics And Perspectives Of Disease At The Wildlife-Livestock Interface In Oceania -- 8 Characteristics And Perspectives Of Disease At The Wildlife-Livestock Interface In North America -- 9 Characteristics And Perspectives Of Disease At The Wildlife-Livestock Interface In Central And South America -- Part 3 Characterization Of The Wildlife-Livestock Interface -- 10 Collecting Data To Assess The Interactions Between Livestock And Wildlife -- 11 Characterization Of Wildlife-Livestock Interfaces: The Need For Interdisciplinary Approaches And A Dedicated Thematic Field -- 12 Quantifying Transmission Between Wild And Domestic Populations -- Part 4 Synthesis And Conclusions -- 13 Synthesis And Future Perspectives Of The Study And Management Of Diseases At The Wildlife-Livestock Interface.

Description / Table of Contents: High pressure and High pressure environments -- High pressure: molecules, chemical processes and cellular structures -- The high pressure micro-environment of vertebrate load bearing joints- Effects of high pressure on the activity of ordinary animals, including humans, and on the function of their excitable cells and ion channels -- The effects of decompression and subsequent re-compression on the activity of deep sea animals and eukaryote cells. The isobaric collection of deep sea animals.-Molecular adaptation to high pressure: proteins in deep sea animals -- Molecular adaptation to high pressure: membranes -- Prokaryotes at high pressure in the Oceans and the Deep Biosphere -- Hydrothermal vents: the inhabitants, their way of life and their adaptation to high pressure -- Buoyancy at depth -- Divers: Air breathing animals, including humans, at high pressure -- Adaptation to high pressure in the laboratory -- High pressure equipment used in the laboratory, at sea and at depth.

Description / Table of Contents: Preface and Introduction -- Part I Risks and Impacts Enhancing the Vulnerability of Social-Ecological Systems -- Part II Environmental and Climate Change Impacts on Social-Ecological Systems – Conflict, Inequality and Human Security -- Part III Human Mobility and Social-Ecological Systems -- Part IV Enhancing the Sustainability and Resilience of Social-Ecological Systems – Some Recommended Paths -- Conclusions.

Description / Table of Contents: Introduction -- Part I. Ethology and Behavioral Ecology of Sea Otters -- Taxonomy and Evolution of Sea Otters -- Sea Otter Behavior: Morphologic, Physiologic, and Sensory Adaptations -- Sea Otter Foraging Behavior -- Social Structure of Marine Otters: Inter and Intraspecific Variation -- Reproductive Behavior of Male Sea Otters -- Reproductive Behavior of Female Sea Otters and Their Pups -- Sea Otter Behavior and Its Influence on Littoral Community Structure -- Sea Otter Predator Avoidance Behavior -- Sea Otters and the Maritime Fur Trade -- Part II. Ethology and Behavioral Ecology of Polar Bears -- Polar Bear Taxonomy and Evolution -- Polar Bear Behavior: Morphologic and Physiologic Adaptations -- Polar Bear Foraging Behavior -- Polar Bear Reproductive and Denning Behavior -- Polar Bear Maternal Care, Neonatal Development, and Social Behavior -- Polar Bear Behavior in Response to Climate Change -- Human-Polar Bear Interactions.

Description / Table of Contents: SECTION I. Natural and human environment of coastal ecosystems -- Chapter 1. Ecological modelling and conservation on the coasts of Mexico -- Chapter 2. SE Pacific: the ecosystem and its use along the Chilean and Peruvian coast -- SECTION II. Marine ecosystem models in the South East Pacific coast -- Chapter 3. Modelling the Northern Humboldt Current Ecosystem; from winds to predators -- Chapter 4. Marine ecosystem models in the South Pacific coast -- Chapter 5. Keystone Species Complexes and macroscopic properties for improving ecosystem-based conservation practices in kelp forest along the north-central Chilean coast -- Chapter 6. Exploring alternative management policies for benthic ecological systems of northern Chile (SE Pacific) -- SECTION III. Central Pacific, Caribbean and Atlantic coastal ecosystem models -- Chapter 7. How much biomass must remain at the sea after fishing to conserve ecosystem -- functioning? The case of the Monterey sardine in the Gulf of California, Mexico -- Chapter 8. Dynamic and spatial model of the coral reef of Banco Chinchorro Biosphere Reserve (Caribbean Sea) for assessment harvest scenarios: short-term responses -- Chapter 9. Ecological role of sharks assessed by Ecopath models -- SECTION IV. System-based conservation and management: conclusions -- Chapter 10. Graph theory in food webs: uses and applications for conservation of marine ecosystems -- Chapter 11. Modelling aim the conservation of coastal marine ecosystem in Latin America.

Description / Table of Contents: Chapter 1 - Ecosystem services as a tool for decision-making in Patagonia -- Chapter 2- Assessment of provisioning ecosystem services in terrestrial ecosystems of Santa Cruz province, Argentina -- Chapter 3 - Grazing management and provision of ecosystem services in Patagonian arid rangelands -- Chapter 4 - Synergies and trade-offs among ecosystem services and biodiversity in different forest types inside and off-reserve in Tierra del Fuego, Argentina -- Chapter 5 - Shrubland management in northwestern Patagonia: an evaluation of its short-term effects on multiple ecosystem services -- Chapter 6 - Silvopastoral systems in northern Argentine-Chilean Andean Patagonia: Ecosystem services provision in a complex territory -- Chapter 7 - Ecosystem services values of the northwestern Patagonian natural grasslands -- Chapter 8 - The ecosystem services provided by peatlands in Patagonia -- Chapter 9 - Restoration for provision of ecosystem services in Patagonia-Aysén, Chile -- Chapter 10 - The North American beaver invasion and the impact over the ecosystem services in the Tierra del Fuego archipelago -- Chapter 11 - Social links for a nexus approach from an ecosystem services perspective in Central-East Patagonia -- Chapter 12 - Salmon farming: is it possible to relate its impact to the waste remediation ecosystem service? -- Chapter 13 - Using the ecosystem services approach to understand the distributional effects of marine protected areas in the Chilean Patagonia -- Chapter 14 - Socio-cultural valuation of ecosystem services in Southern Patagonia, Argentina -- Chapter 15 - Looking beyond ecosystem services supply: co-production and access barriers in marine ecosystems of the Chilean Patagonia -- Chapter 16 - Ecosystem services and human well-being: a comparison of two Patagonian social-ecological systems -- Chapter 17 - Urban Planning In Arid Northern Patagonia Cities To Maximize Local Ecosystem Services Provision -- Chapter 18 - Land size, native forests and ecosystem services inequalities in the rural Chilean Patagonia -- Chapter 19 - Imaginaries, transformations and resistances in Patagonian territories from a socio-ecological perspective -- Chapter 20 - The challenges of implementing ecosystem services in the Argentinean and Chilean Patagonia -- Chapter 21 - Natural capital and local employment in Argentine Patagonia -- Chapter 22 - Ecosystem services in Patagonia: a synthesis and future directions. .

Description / Table of Contents: The Origin of Eukaryotic Cells and Multicellular Organisms -- Multicellular Organisms Propagation -- Grow Fast and Well or Die -- Why Do Animals Grow, Age and then Die? -- How Do Tissues Regenerate After an Injury? Epilog. The Future of Humankind Could Depend on Unicellular Life.

Description / Table of Contents: Recent Advances in the Generation of β-cells from Induced Pluripotent Stem Cells As a Potential Cure for Diabetes Mellitus -- Differentiated cells derived from hematopoietic stem cells and their applications in translational medicine -- Organoids in Tissue Transplantation -- Aldo keto reductases AKR1B1 and AKR1B10 in cancer: molecular mechanisms and signaling networks -- Bilayer Scaffolds for Interface Tissue Engineering and regenerative medicine: A Systematic Review -- Pluripotent Stem Cell Derived Neurons as In Vitro Models for Studying Autosomal Recessive Parkinson’s Disease (ARPD): PLA2G6 and Other Gene Loci -- Stem Cell Applications In Lysosomal Storage Disorders: Progress And Ongoing Challenges -- Mechanisms of Drug Resistance and Use of Nanoparticle Delivery to Overcome Resistance in Breast Cancers -- Telomere length and oxidative stress in patients with St-elevation and Non-St-elevation myocardial infarction -- Eosinophils as major player in Type 2 inflammation: autoimmunity and beyond.

Description / Table of Contents: Induced pluripotent stem cell derived human lung organoids to map and treat the SARS-CoV2 infections in vitro -- Embryonic Stem Cells in Clinical Trials: Current Overview of Developments and Challenges -- Functions of Mesenchymal Stem Cells in Cardiac Repair -- Cardiac Progenitor Cells -- Cardiac Immunology: a new era for immune cells in the heart -- Conventional and Alternative Mesenchymal Stem Cell Therapies for the Treatment of Diabetes -- Mesenchymal stem cells: The past present and future -- Extracellular vesicles therapeutics in regenerative medicine -- Exosomes as part of the human adipose-derived stem cells secretome- opening new perspectives for cell-free regenerative applications -- A Museum of Stem Cells Points to Muse Cells as Robust Transplantable Cells for Stroke.

Description / Table of Contents: Immune dysregulation and recurring mutations in myelodysplastic syndromes pathogenesis -- Stem Cell Aging and Regenerative Medicine -- Potential of Chimeric Antigen Receptor T-cells in cancer therapy -- Drug sensitivity and drug repurposing platform for cancer precision medicine -- Role and regulation of Lin28 in progenitor cells during central nervous system development -- Cartilage Repair by Mesenchymal Stem Cell-Derived Exosomes: Preclinical and Clinical Trial Update and Perspective -- Kaempferol induce cell death and sensitizes human head and neck squamous cell carcinoma cell lines to cisplatin -- A comprehensive approach to Urticaria: from clinical presentation to modern biological treatments through pathogenesis -- The potentials and pitfalls of using adult stem cells in cancer treatment -- The Outcome of Stem Cell-Based Therapies on the Immune Responses in Rheumatoid Arthritis.

Description / Table of Contents: In Vivo Optical Imaging and Manipulation of Brain Pericytes -- The complex and integral roles of pericytes within the neurovascular unit in health and disease -- Role of pericytes in brain metastasis -- Effects of Cytomegalovirus on Pericytes -- Pericytes in Retinal Ischemia -- Inflammatory mediators released by brain pericytes as sensors and effectors in blood-brain barrier dysfunction -- TLR-4 signaling in Pericytes -- EphA7+ Multipotent Pericytes and Their Roles in Multicellular Organisms -- Skeletal Muscle-Resident Pericyte Responses to Conditions of Use and Disuse -- Pericytes in myocardial diseases -- Adventitial and skeletal muscle pericytes in health and in ischemic tissue regeneration.

Description / Table of Contents: Chapter 1: Introduction to the collagen superfamily -- Chapter 2: Collagen IV-related disease -- Chapter 3: Articular collagens related diseases -- Chapter 4: Collagens as new players of nervous system disease -- Chapter 5: Collagens and EDS -- Chapter 6: Collagens and dystrophic epidermolysis bullosa -- Chapter 7: Collagen-related myopathies: pathogenic mechanisms and prospective therapies -- Chapter 8: Procollagen trafficking and its implicaitons in Osteogenesis Imperfecta.

Description / Table of Contents: Foreword -- Preface -- PART I: Evolution, genetics and distribution -- 1. Phylogenesis and evolution -- 2. Population genetics and genomics -- 3. Conservation and breeding -- 4 Biogeography and local adaptations -- 5. Mediterranean pines as invasive species -- PART II: Ecophysiology of Mediterranean pines: resistance to stress and perturbation -- 6. Physiological trade-offs under stress and perturbation -- 7. Carbon allocation dynamics under stress -- 8 -- Root systems under drought -- 9. Stress and tree mortality -- 10. Forest diseases affecting pines -- 11. Resistance to herbivorous insects -- PART III: Pine and mixed forest ecosystems under global climate change -- 12. Growth and vigor -- 13. Forest distribution resilience under climate change -- 14. Carbon and energy balance -- 15. Soil properties and biogeochemical functioning -- 16. Decomposition -- PART IV: Forest dynamics, biodiversity and biotic interactions -- 17. Dynamics of mixed pine-oak forests -- 18. Bird diversity -- 19 Soil micro- and macrofauna -- 20. Mycorhizae -- PART V: Forest fire ecology and management -- 21. Fire past present and future -- 22. Adaptations to fire -- 23. Post-fire soil erosion -- 24. The impact of grazing on understory fuel load -- 25. Post fire restoration -- 26. Predicting post-fire conifer regeneration in California -- 27. Remote sensing fire damage -- PART VI: Policy and Ecosystem services of Mediterranean pine and mixed forest ecosystems -- 28. Mediterranean forests and the United Nations sustainable development goals -- 29. Ecosystem services -- 30.Multi-disciplinary assessment of cultural ecosystem services supplied by Mediterranean pine and mixed forests -- PART VII: Afforestation and forest management policy -- 31. Dynamics and management of western Mediterranean pinewoods -- 32. From pine monoculture forests into sustainable mixed forest ecosystems -- 33. Forest policy in Israel -- 34. Water based forest management.

Description / Table of Contents: 1.Extracellular Vesicle-associated Moonlighting Proteins: HSP and Metalloproteinases -- 2.Heat Shock Proteins and Periodontitis ― Crossreaction between Bacterial and Human HSP in Periodontal Infection Linking with Cardiovascular Diseases -- 3.Protective Role of Heat Shock Proteins during Neurodegeneration in Parkinson's Disease -- 4.HSP Stimulation on Macrophages and Dendritic Cells Activates Innate Immune System -- 5.Heat Shock Factor 1 and its Small Molecule Modulators with Therapeutic Potential -- 6.Heat Shock Proteins, a Key Modulator of Neuroinflammation in Alzheimer’s Disease -- 7.Role of Heat Shock Factor 1 in HIV -- 8.Heat Shock Protein and Cancer Based Therapies -- 9.Effects of Heat Shock Protein 70 kDa in Allergic Airway Inflammation -- 10.Role of Heat Shock Factor 1 in Neural Development and Disorders -- 11.Small Heat Shock Proteins in Inflammatory Diseases -- 12.Overview of Multifaceted Role and Significance of Heat Shock Proteins during Inflammation, Apoptosis and Other Diseases -- 13.Heat Shock Proteins as Target Autoantigens in Autoimmune Rheumatic Diseases -- 14.DNAJA3, a Co-chaperone in Development and Tumorigenesis -- 15.Therapeutic Potential of Heat Shock Proteins in Human Inflammation/Autoimmune Skin Diseases: Future Directions -- 16.Role of HSP in the Pathogenesis of Age-related Inflammatory Diseases -- 17.Heat Shock Factor Network in Kidney Diseases -- 18.Binary Role of Heat Shock Proteins in Cancer Immunotherapy: A Detailed Perspective -- 19.The role of heat shock proteins in reproductive functions -- 20.Heat shock proteins 70 in cellular stress: fight or flight -- 21.Indispensable role of protein turnover in autophagy, apoptosis and ubiquitination pathways -- 22.Heat Shock Proteins in Leishmania Parasites -- 23.HSF1 in RNA Polymerase II Promoter-Proximal Pausing and HSP70 Transcription -- 24.Induction of HSPA1A and Autophagy by SARS-CoV-2: Combined Potential Influence on Pregnancy Outcome.

Description / Table of Contents: 1. Introduction: Randall W. Myster -- 2. Dynamics of Andean Treeline Ecotones: Between Cloud Forest and Páramo Geocritical Tropes. Fausto O. Sarmiento -- 3. ANÁLISIS REGIONAL EN ECOSISTEMAS DE MONTAÑA EN COLOMBIA:Una mirada desde la funcionalidad del paisaje y los servicios ecosistémicos. Paola Isaacs-Cubides, Julián Díaz and Tobias Leyva-Pinto -- 4. Ecohydrology of Tropical Andean Cloud Forests. Conrado Tobon Martin -- 5. Litterfall in Andean forests: Quantity, composition, and environmental drivers. Wolfgang Wilcke -- 6. Arbuscular Mycorrhizal Fungi and Ectomycorrhizas in the Andean Cloud Forest of South Ecuador. Ingeborg Haug, Sabrina Setaro, Juan Pablo Suárez -- 7. Nesting ecology of the Tucuman Amazon (Amazona tucumana) in the cloud forest of Northwestern Argentina. Luis Rivera and Natalia Politi -- 8. Adaptive strategies of frugivore bats to Andean cloud forests. Adriana Ruiz and Pascual J. Soriano -- 9. Diversification and dispersal of Neotropical fauna: Processes and patterns in Andean species diversity. Juan C. Garcia-Ramirez and Angela M. Mendoza-Henao -- 10. Mapping Hydrological Ecosystem Services and Impacts of Scenarios for Deforestation and Conservation of Lowland, Montane and Cloud-Affected Forests. Mark Mulligan -- 11. Randall W. Myster. Conclusions, synthesis and future directions.

Description / Table of Contents: Conventional and Emerging Markers in Stem Cell Isolation and Characterization -- Therapeutic Potential of Adipose Stem Cells -- Decellularized Extracellular Matrix as a Potent Natural Biomaterial for Regenerative Medicine -- Stem Cell Based Exosomes: Are They Effective in Disease or Health? -- Interests of Exosomes in Bone and Periodontal Regeneration: A Systematic Review -- The Design and Application of an Appropriate Parkinson's Disease Animal Model in Regenerative Medicine -- Cell Therapy Targets for Autism Spectrum Disorders: Hopes, Challenges and Future Directions -- Regenerative Medicine Perspectives in Polycystic Ovary Syndrome -- Opportunities and Challenges in Stem Cell Aging -- Role of Tumor Specific niche in Colon Cancer Progression and Emerging Therapies by Targeting Tumor Microenvironment.

Description / Table of Contents: Stress and Poverty: An Introduction -- Hans Selye and the Origins of Stress Research -- Oxidative and Other Stress Research at the Cellular Level -- Oxidative Stress and the Brain: A Working Hypothesis for the Generation of Psychological Stress -- Epigenetics and Some Further Observations on Stress-induced Diseases -- Measuring Stress -- The Language Games of Stress -- The Unhealthy Relationship Between Stress and Poverty -- The Stressful Experience of Poverty -- Social and Moral Aspects of Stress -- The Politics of Stress -- Responding to Stress and the Value of Resilience -- Epilogue – The Pandemic as a Big Reveal: Coronavirus, Stress, and Poverty -- Glossary.

Description / Table of Contents: Chapter 1: Introduction -- Chapter 2: Regional context and maritime governance -- Chapter 3: Alboran Sea area climate and weather -- Chapter 4: The Oceanographic and climatic context -- Chapter 5: A Geological history for the Alboran Sea region -- Chapter 6: Seafloor morphology and processes in the Alboran Sea -- Chapter 7: The biogeochemical context of marine planktonic ecosystems -- Chapter 8: Seaweeds and seagrasses: the marine forests from the Alboran Sea -- Chapter 9: Benthic fauna of littoral and deep-sea habitats of the Alboran Sea: A hotspot of biodiversity -- Chapter 10: Invertebrates: the realm of diversity -- Chapter 11: Biogeographical and Macroecological context of the Alboran Sea -- Chapter 12: Biophysical processes determining the connectivity of the Alboran Sea fish populations -- Chapter 13: Evolving from fry fisheries to early life research on pelagic fish resources -- Chapter 14: Description of artisanal fisheries in northern Alboran Sea -- Chapter 15: Description of artisanal fisheries in southern Alboran Sea -- Chapter 16: Small pelagic resources: A historic perspective and current state of the resources -- Chapter 17: North Atlantic Oscillation effect on the biology and fisheries of tunas species in the Alboran Sea -- Chapter 18: Demersal Resources -- Chapter 19: The Blackspot seabream fishery in the Strait of Gibraltar: lessons and future perspectives of shared marine resource -- Chapter 20: Aquaculture in the Alboran Sea -- Chapter 21: Marine megafauna and charismatic vertebrate species -- Chapter 22: Fisheries economics and management under the impact of Human and varying marine environmental conditions in the Alboran Sea -- Chapter 23: A historical approach to living resources on the Spanish coasts from Alboran Sea between the 16th and 20th centuries -- Chapter 24: Sustainable development and Blue growth in the Alboran Sea: enabling ocean health and ecosystem services through ocean science and equitable governance -- Chapter 25: Marine Protected Areas and Key Biodiversity Areas of the Alboran Sea and adjacent areas.

Description / Table of Contents: A View of the Endoplasmic Reticulum Through the Calreticulin Lens -- Structural Analysis of Calreticulin, an Endoplasmic Reticulum-Resident Molecular Chaperone -- The Role of Endoplasmic Reticulum Chaperones in Protein Folding and Quality Control -- Proteins Interacting with STIM1 and Store-Operated Ca2+ Entry -- Endoplasmic Reticulum (ER) and ER-Phagy -- Defects in Protein Folding and/or Quality Control Cause Protein Aggregation in the Endoplasmic Reticulum -- Roles of Calreticulin in Protein Folding, Immunity, Calcium Signaling and Cell Transformation -- Impact of Calreticulin and Its Mutants on Endoplasmic Reticulum Function in Health and Disease -- Cancer Biology of the Endoplasmic Reticulum Lectin Chaperones Calreticulin, Calnexin and PDIA3/ERp57 -- Maintenance of Endoplasmic Reticulum Protein Homeostasis in Cancer: Friend or Foe -- IP3 Receptor Biology and Endoplasmic Reticulum Calcium Dynamics in Cancer -- Disruption of Endoplasmic Reticulum Proteostasis in Age-Related Nervous System Disorders -- Endoplasmic Reticulum Homeostasis and Stress Responses in Caenorhabditis elegans -- Tardigrada: An Emerging Animal Model to Study the Endoplasmic Reticulum Stress Response to Environmental Extremes. .

Description / Table of Contents: Micro-Electrode-Arrays: A valuable tool to analyze stem cell derived cardiomyocytes -- CD34+ STEM CELLS AND REGENERATIVE MEDICINE -- Mesenchymal-Hematopoietic Stem Cell Axis: Applications for Induction of Hematopoietic Chimerism and Therapies for Malignancies -- Mesenchymal stem cell-derived secretome: a new remedy for the treatment of autoimmune and inflammatory diseases -- Cardiac regenerative therapy in diabetes: challenges and potential therapeutics -- Macrophage Response to Biomaterials in Cardiovascular Applications -- Evolution of stem cells in cardio-regenerative therapy -- Stem cell-based cardiac regeneration: is there a place for optimism in the future? -- Dental mesenchymal stem/progenitor cells: A new prospect in regenerative medicine -- Stem cell-based tissue engineering for functional enamel and dentin/pulp complex: a potential alternative to the restorative therapies -- Cell and stem cell-based therapies for liver defects: Recent advances and future strategies -- Stem cells: a renewable source of pancreatic β-cells and future for diabetes treatment -- Induced pluripotent stem cells in pediatric research and clinical translation -- Maturity of Pluripotent Stem Cell-Derived Cardiomyocytes and Future Perspectives for Regenerative Medicine -- Availability of pluripotent stem cells from normal cells in cancer science -- Index.

Description / Table of Contents: Basics of stem cell biology -- Types and classifications stem cells -- Method of isolation and characterization of stem cells -- Differentiation of stem cells into neuronal lineage: In vitro cell culture, In vivo transplantation in animal models -- Differentiation of stem cells into cardiomyocyte lineage: In vitro cell culture, In vivo transplantation in animal models -- Differentiation of stem cells into hepatocyte lineage: In vitro cell culture, In vivo transplantation in animal models -- Differentiation of stem cells into pancreatic lineage: In vitro cell culture, In vivo transplantation in animal models -- Application of stem cells in treatment of bone diseases: pre-clinical and clinical perspectives -- Stem cells in regenerative medicine: clinical trials -- Stem cell production: Scale up, GMP production, Bioreactor -- Stem cell based products in the market -- Commercialization, IPR and market of stem cell products.

Description / Table of Contents: Ecosystem Collapse and Climate Change: An Introduction -- PART I. Polar and Boreal Ecosystems -- Ecosystem Collapse on a Sub-Antarctic Island -- Permafrost Thaw in Northern Peatlands: Rapid Changes in Ecosystem and Landscape Functions -- Post-fire Recruitment Failure as a Driver of Forest to Non-forest Ecosystem Shifts in Boreal Regions -- A Paleo-perspective on Ecosystem Collapse in Boreal North America -- PART II. Temperate and Semi-arid Ecosystems -- The 2016 Tasmanian Wilderness Fires: Fire Regime Shifts and Climate Change in a Gondwanan Biogeographic Refugium -- Climate-Induced Global Forest Shifts due to Heatwave-Drought -- Extreme Events Trigger Terrestrial and Marine Ecosystem Collapses in the Southwestern USA and Southwestern Australia -- PART III. Tropical and Temperate Coastal Ecosystems -- Processes and Factors Driving Change in Mangrove Forests: An Evaluation Based on the Mass Dieback Event in Australia’s Gulf of Carpentaria -- Recurrent Mass-Bleaching and the Potential for Ecosystem Collapse on Australia’s Great Barrier Reef -- Sliding Toward the Collapse of Mediterranean Coastal Marine Rocky Ecosystems -- Marine Heatwave Drives Collapse of Kelp Forests in Western Australia -- Impact of Marine Heatwaves on Seagrass Ecosystems.

Description / Table of Contents: Basic semiologic principles to define coherent color palettes for vegetation mapping -- Plant species distributions and ecological complexity: mapping sampling-effort bias explicitly -- Mapping of biogeographical territories: flora, vegetation and landscape criteria -- Dynamic-catenal vegetation mapping as a tool for ecologic restoration, conservation and policy -- Climate Change, Wetland Management and Alpaca Pastoralism in the Bolivian High Andes Mountains -- Essays on geobotanic mapping in the Andes of Bolivia, with particular reference to the conservation status of vegetation -- Using geobotanical tools to map and assess ecosystem services (MAES) in southern Portugal -- Spatial representation of plant diversity at geographical scale: the Italian experience -- Cognitive mapping of forest fragments -- California ultramafic vegetation: a phytosociological update -- Plant associations of the Petasition officinalis alliance in the east Carpathians (Călimani and Gurghiu Mountains) -- Arthrocaulon (Arthrocnemum) macrostachyum plant communites in the Iberian Peninsula, Balaeric and Canary Islands (Spain and Portugal) -- Geosynphytosociological typology of the French atlantic coastal rocky cliffs vegetations -- Symphytosociology: a tool for landscape monitoring: case study from the Swiss Alps -- Why does Mediterranean vegetation seem so diverse? -- Coastal dune vegetation zonation in Italy: squeezed between environmental drivers and threats -- Topographic and other constraints on evergreen broad-leaved forests in the southeastern USA -- Role of riparian zones in reducing pollution of surface and ground water, and increasing agricultural production nutrient acquisition and storage in river catchments -- Vegetation and flora of sacred natural sites in northwestern Morocco – landscape context and conservation value -- The Kaga Coast in Japan: Natural ecosystem and cultural landscape insuring biodiversity -- Species and habitat biodiversity measurement and conservation at different fine scales.

Description / Table of Contents: Application of iPSC to modelling of respiratory diseases -- Gene editing in human pluripotent stem cells: recent advances for clinical therapies -- Vascular wall as source of stem cells able to differentiate into endothelial cells -- Physiological and therapeutic roles of neuropeptide Y on biological functions -- Rho signaling-directed YAP/TAZ regulation encourages 3D spheroid colony formation and boosts plasticity of Parthenogenetic Stem Cells -- Transamniotic Stem Cell Therapy -- Regenerative medicine: Injectable cell-based therapeutics and approved products -- Stem Cell Therapy for Hepatocellular Carcinoma: Future Perspectives -- Potential of tribological properties of metalnanomaterials in biomedical applications -- The impact of the low frequency of the electromagnetic field on human.

Description / Table of Contents: Data Analysis of Infection Rates Among Exposed Healthcare Workers Could Reveal Effective Prophylactics Against SARS-CoV-2 -- Immune Responses to SARS-CoV, MERS-CoV AND SARS-CoV-2 -- Normothermic Preservation of Liver – What does the Future Hold? -- Tissues from Post-Mortem Donors as Alternative Sources of Stem Cells for Regenerative Medicine -- New Pioneers of Optogenetics in Neuroscience -- A Current Overview of Scaffold-Based Bone Regeneration Strategies with Dental Stem Cells -- The Importance of Stem Cell Senescence in Regenerative Medicine -- Hematological Malignancies and Fertility -- Unraveling polymeric nanoparticles cell uptake pathways: two decades working to understand nanoparticles journey to improve gene therapy -- Cellular Dust as a Novel Hope for Regenerative Cancer Medicine.

Description / Table of Contents: Apelin Receptor Signaling During Mesoderm Development -- Epidermal stem cells in regenerative medicine -- The cellular and molecular patterns involved in the neural differentiation of adipose-derived stem cells -- Biomatrices for heart regeneration and cardiac tissue modelling in vitro -- Dentin-Pulp Tissue Regeneration Approaches in Dentistry: An Overview and Current Trends -- Stem Cell Culture under Simulated Microgravity -- Smart Polymeric Systems: A Biomedical Viewpoint -- Acute lung injury: Disease modelling and the therapeutic potential of stem cells -- COVID-19 and Mesenchymal Stem Cell Treatment; Mystery or Not -- PCDH19 pathogenic variants in males: Expanding the phenotypic spectrum.

Description / Table of Contents: Preface -- The marine physical environment during the Polar Night -- Light in the Polar Night -- Marine micro- and macroalgae in the Polar Night -- Zooplankton in the Polar Night -- Benthic communities in the Polar Night -- Fish ecology in the Polar Night -- Biological clocks and rhythms in polar organisms -- Sensor carrying platforms -- Operative habitat mapping and monitoring in the Polar Night -- The Polar Night exhibition: Life and light at the dead of night -- Index.

Description / Table of Contents: Part I. Cancer -- Ubiquitin-Regulated Cell Proliferation and Cancer -- Ubiquitin, SUMO, and Nedd8 as Therapeutic Targets in Cancer -- The Proteasome System in Health and Disease -- Proteostasis Dysregulation in Pancreatic Cancer -- Divergent Modulation of Proteostasis in Prostate Cancer -- Resistance to the Proteasome Inhibitors: Lessons from Multiple Myeloma and Mantle Cell Lymphoma -- Part II. Neurodegeneration -- Altered Proteostasis in Neurodegenerative Tauopathies -- The Ubiquitin System in Alzheimer’s Disease -- The Interplay Between Proteostasis Systems and Parkinson’s Disease -- Machado–Joseph Disease: A Stress Combating Deubiquitylating Enzyme Changing Sides -- Part III. Infection, Inflammation and Developmental Disorders -- SUMO and Cytoplasmic RNA Viruses: From Enemies to Best Friends -- The Role of Proteostasis in the Regulation of Cardiac Intercellular Communication -- By the Tips of Your Cilia: Ciliogenesis in the Retina and the Ubiquitin-Proteasome System -- TRIM E3 Ubiquitin Ligases in Rare Genetic Disorders -- Part IV. Diet -- We Are What We Eat: Ubiquitin–Proteasome System (UPS) Modulation Through Dietary Products.

Description / Table of Contents: 1. The BRCA1 and BRCA2 genes in early onset breast cancer patients -- 2. Anti-cancer effect of Xao tam phan Paramignya trimera methanol root extract on human breast cancer cell line MCF-7 in 3D model -- 3. A novel nonsense mutation c.374C〉G in CYP21A2 gene of a Vietnamese patient with congenital adrenal hyperplasia -- 4. Variation of Mitochondrial DNA HV1 AND HV2 of the Vietnamese Population -- 5. Synthesis and Characterization of PLGA-PEG Thymoquinone Nanoparticles and its Cytotoxicity Effects in Tamoxifen-resistant Breast Cancer Cells -- 6. Adipose-derived mesenchymal stem cells promote growth and migration of lung adenocarcinoma cancer cells -- 7. Predictive potential of PD-L1, TYMS and DCC expressions in treatment outcome of colorectal carcinoma -- 8. Clinical trials with cytokine-induced killer cells and CAR-T cell transplantation for non-small cell lung cancer treatment -- 9. Isopanduratin A isolated from Boesenbergia pandurata reduces HepG2 hepatocellular carcinoma cell proliferation in both monolayer and three-dimensional cultures -- 10. Hopea Odorata extract can efficiently kill breast cancer cells and cancer stem like cells in three-dimensional culture more than in monolayer cell culture -- 11. Selective cytotoxicity of some plant extracts against hepatocellular carcinoma cells but not mesenchymal stem cells: A pilot screening.

Description / Table of Contents: Chapter 1: Introduction: Ecological Subsidies as a Framework for Understanding Contaminant Fate, Exposure, and Effects at the Land-Water Interface -- Part I: Ecological Subsidies Drive Exposure -- Chapter 2: Ecological Factors Controlling Insect-Mediated Methylmercury Flux from Aquatic to Terrestrial Ecosystems: Lessons Learned from Mesocosm and Pond Experiments -- Chapter 3: Pathways of Contaminant Transport Across the Aquatic-Terrestrial Interface: Implications for Terrestrial Consumers, Ecosystems and Management -- Part II: Exposure Drives Ecological Subsidies -- Chapter 4: Agriculture and Mining Contamination Contribute to a Productivity Gradient Driving Cross-Ecosystem Associations between Stream Insects and Riparian Arachnids -- Chapter 5: Cross-Ecosystem Linkages and Trace Metals at the Land-Water Interface -- Chapter 6: Metamorphosis and the Impact of Contaminants on Ecological Subsidies -- Part III: Other Global Stressors -- Chapter 7: Variables Affecting Resource Subsidies from Streams and Rivers to Land and their Susceptibility to Global Change Stressors -- Chapter 8: Beyond “Donors and Recipients”: Impacts of Species Gains and Losses Reverberate among Ecosystems due to Changes in Resource Subsidies -- Part IV: Management Applications and Tools -- Chapter 9: Practical Considerations for the Incorporation of Insect-Mediated Contaminant Flux into Ecological Risk Assessments -- Chapter 10: When Nutrients Become Contaminants in Aquatic Systems: Identifying Responses to Guide Terrestrial-Derived Detrital Endpoint Development for Managers -- Chapter 11: Mesocosms to Evaluate Aquatic-Terrestrial Contaminant Linkages using Aquatic Insect Emergence: Utility for Aquatic Life Criteria Development -- Chapter 12: Studying Effects of Contaminants on Aquatic-Terrestrial Subsidies: Experimental Designs using Outdoor and Indoor Mesocosms and Microcosms -- Part V: Syntheses -- Chapter 13: Ecological Networks as a Framework for Understanding and Predicting Contaminant Movement across the Land-Water Interface -- Chapter: 14: Synthesis: A Framework for Predicting the Dark Side of Ecological Subsidies.

Description / Table of Contents: Introduction -- Porosome: Cells Secretory Nanomachine -- Ubiquitin-Proteasome Machinery: Cells Garbage Disposal -- Chaperonin: Protein Folding Machinery in Cells -- ATP Synthase: Energy Generator of the Cell -- Ribosome: Cells Protein Synthetic Machinery -- Nuclear Pore: A Bidirectional Transport Machinery -- Myosin: Cellular Molecular Motor -- Assembly of Cellular Nanomachines. Index.

Description / Table of Contents: Shaping of the tumor microenvironment by Notch signaling -- Erythropoietin signaling in the microenvironment of tumors and healthy tissues -- Neuropilin – handyman and power broker in the tumor microenvironment -- Translational landscape of mTOR signaling in integrating cues between cancer and tumor microenvironment -- Toll-like receptors signaling in the tumor microenvironment -- Rho-ROCK signaling in normal physiology and as a key player in shaping the tumor microenvironment -- S1P signaling in the tumor microenvironment -- CD200-CD200R pathway in the regulation of tumor immune microenvironment and immunotherapy -- Index.

Description / Table of Contents: Neutrophils in the Tumor Microenvironment -- Basophils in Tumor Microenvironment and Surroundings -- Janus or Hydra: The many faces of T helper cells in the human tumour microenvironment -- Cytotoxic CD8+ lymphocytes in the tumor microenvironment -- Mucosal-associated invariant T cells in tumors of epithelial origin -- Fibrocytes in the Tumor Microenvironment -- Models for Monocytic Cells in the Tumor Microenvironment -- Myeloid-Derived Suppressor Cells in the Tumor Microenvironment -- Index.

Description / Table of Contents: Cathepsin D in the tumor microenvironment of breast and ovarian cancers -- Galectins in the tumor microenvironment: Focus on galectin-1 -- Iron in the tumor microenvironment -- Oxygen in the tumor microenvironment: mathematical and numerical modeling -- Roles for Phospholipase D1 in the tumor microenvironment -- Leptin in tumor microenvironment -- The immune consequences of lactate in the tumor microenvironment -- Fatty acid mediators in the tumor microenvironment -- Extracellular Vesicles in the tumor microenvironment: various implications in tumor progression -- Index.

Description / Table of Contents: 1. Introduction: aquatic insects in Australia’s environments -- 1.1. The background to concern -- References -- 2. Major habitats -- 2.1. Introduction -- 2.2. Ponds and lakes -- 2.3. Streams and rivers -- References -- 3. Australian inland waters -- 3.1. Introduction -- 3.2. Waterfalls -- 3.3. Subterranean aquifers -- 3.4. Rock pools -- 3.5. Mound springs -- 3.6. Lakes -- 3.7. Billabongs -- 3.8. Streams and rivers -- 3.9. Exposed riverine sediments -- References -- 4. Monitoring freshwater macroinvertebrates -- 4.1. Scope and needs for assessments -- References -- 5. Threats: the background variations in condition -- 5.1. Introduction -- 5.2. Drought -- 5.3. Flood -- References -- 6. Major imposed threats -- 6.1. Introduction -- 6.2. Water temperature -- 6.3. Sedimentation -- 6.3.1. Mining -- 6.4. Pollution -- 6.5. Salinisation -- 6.6. Exploitation -- 6.7. Electrofishing -- 6.8. Changes to riparian vegetation -- 6.8.1. Emergent vegetation -- 6.9. Alien species -- 6.9.1. Plants -- 6.9.2. Fish -- 6.9.3. Mammals -- 6.10. River regulation -- 6.11. Fire -- 6.12. Urbanisation -- 6.13. Recreation -- 6.14. Ecological traps -- 6.15. Climate change -- References -- 7. Macroinvertebrates of inland waters -- 7.1. Introduction -- 7.2. The variety of aquatic insects -- 7.3. Other macroinvertebrates -- 7.3.1. Crustaceans -- 7.3.2. Molluscs -- References -- 8. Insects of Australia’s inland waters -- 8.1. Introduction -- 8.2. Ephemeroptera -- 8.3. Odonata -- 8.4. Plecoptera -- 8.5. Hemiptera -- 8.6. Coleoptera -- 8.7. Mecoptera -- 8.8. Megaloptera -- 8.9. Neuroptera -- 8.10. Lepidoptera -- 8.11. Trichoptera -- 8.12. Diptera -- 8.12.1. Control of aquatic pest flies -- References -- 9. Australia’s flagship freshwater insects -- 9.1. Introduction -- 9.2. Selected flagship taxa -- References -- 10. Ecology and management -- 10.1. Introduction -- 10.2. Dispersal -- 10.2.1. Impacts of urban lighting -- 10.2.2. Pond colonization -- References -- 11. Conservation -- 11.1. Introduction -- 11.2. Protected areas -- 11.3. Management and restoration -- 11.4. Fish conservation -- 11.5. Education and involvement -- 11.6. Artificial water bodies -- 11.7. Temporary ponds -- 11.8. Intermittent streams -- 11.9. Stormwater retention ponds -- 11.10. Refuges -- 11.11. Woody debris -- 11.12. Riparian zones -- 11.13. Perspective and prospects -- References -- Appendix 1 -- Index.

Description / Table of Contents: The future of stem cell research and its clinical translation in Canada: Exploring questions of governance and policy options -- Future cell and gene therapy for osteoarthritis (OA): potential for using mammalian protein production platforms, irradiated and transfected protein packaging cell lines for over-production of therapeutic proteins and growth factors -- The Horizon of Gene Therapy in Modern Medicine: Advances and Challenges -- Developments in Artificial Platelet and Erythroid Transfusion Products -- Advancing mesenchymal stem cell therapy with CRISPR/Cas9 for clinical trial studies -- Mesenchymal Stem Cells in Asthma -- Oocyte Aging: the Role of Cellular and Environmental Factors and Impact on Female Fertility -- Targeting Cancer Metabolism and Cell Cycle by Plant-derived Compounds -- Differentiation potential of Mesenchymal Stem Cells into Pancreatic β-Cells -- Zooming in across the Skin: A Macro-to-Molecular Panorama.

Description / Table of Contents: Introduction -- Assays for thiols and modifications -- Pitfalls of ROS measurements by fluorescent probes and mitochondrial superoxide determination using MitoSOX -- Methods and Reagents -- Clinical Probes for ROS and Oxidative Stress -- Measurement of oxidative stress markers in vitro using commercially available kits -- Oxidative Lipidomics - Analysis of Oxidized Lipids and Lipid Peroxidation in Biological Systems with Relevance to Health & Disease -- Clinically Related Models and Approaches -- Oxidant-Induced Models of Vascular Leak -- Ozone-Specific’ Oxysterols and Neuronal Cell Signaling -- Measurement Oxidative Stress Status in Human Populations: A Critical Need for a Metabolomic Approach -- Instrumental Methods -- Sense and Sensibility of Oxygen in Pathophysiology using EPR Oximetry -- Resonators for Clinical EPR -- Biomedical Overhauser Magnetic Resonance Imaging (OMRI). Noninvasive Imaging of Redox Processes -- Index.

Description / Table of Contents: The intestinal tumour microenvironment -- Gastric Tumor Microenvironment -- Parathyroid tumor microenvironment -- Microenvironment in Cardiac Tumor Development: What Lies Beyond the Event Horizon? -- The roles of bone marrow-resident cells as a microenvironment for bone metastasis -- Adipose tumor microenvironment -- Appendix Tumor Microenvironment -- Spinal cord tumor microenvironment -- Cancer stem cell niche and immune-active tumor microenvironment in testicular germ cell tumors -- Tumor microenvironment in skin carcinogenesis -- Index.

Description / Table of Contents: Part I: Ecosystem Services Basics -- Chapter 1. Overview of the ecosystem services concept -- Part II: Ecosystem Services of Slovakia -- Chapter 2. Methodology of national ES assessment -- Chapter 3. Provisioning ecosystems services -- Chapter 4. Regulatory ecosystem services and supporting ecosystem functions -- Chapter 5. Cultural ecosystems services -- Part III: Synthesis -- Chapter 6. Synthesis of ecosystem services assessment in Slovakia.

Description / Table of Contents: IL-1 signaling in tumor microenvironment -- Interleukin-8 in the Tumor Immune Niche: Lessons from Comparative Oncology -- IL-9 and Th9 cells in tumor immunity -- IL-17 signaling in the tumor microenvironment -- Emerging roles for Interleukin-18 in the gastrointestinal tumor microenvironment -- IL-21 signaling in the tumor microenvironment -- ST2 signaling in the tumor microenvironment -- IL-36 Signaling in the Tumor Microenvironment -- Index.

Description / Table of Contents: Part I: Introductory Communications -- Chapter 1. Our Future and The Oceans -- Chapter 2. General guidelines for future exchanges in marine science and technology between the two Sociétés franco-japonaises d’Océanographie -- Part II: Identification and Analysis of Environmental Stressors -- Chapter 3. The Japan Sea: a changing Pacific Asian marginal sea -- Chapter 4. Statistical analysis of surface circulation in Sagami Bay using High Frequency（HF）Radar -- Chapter 5. Statistical analysis of high frequency pCO2 data acquired with the Astan buoy (Southern Western English Channel, off Roscoff) -- Chapter 6. Spatial variation in pCO2 based on 16 years of in-situ measurements in the Seto Inland Sea, Japan -- Chapter 7. The Bay of Seine: a resilient socio-eco-system under cumulative pressures -- Chapter 8. Effect of bacterial infection on the expression of stress proteins and antioxidative enzymes in Japanese flounder -- Part III: Impacts on Socio-Eco-Systems and Biological Resources -- Chapter 9. A Review of the Effects of Global Warming and Currents Trends on Fisheries and its Impact on Important Commercial Species in Japan -- Chapter 10. Physiology of winter coral bleaching in temperate zone -- Chapter 11. Preliminary report of impacts of the 2011 earthquake and tsunami and subsequent events on macrobenthic community in a shallow brackish lagoon in Sendai Bay, Japan -- Chapter 12. Post-tsunami oyster feeding environment in Nagatsuraura Bay for three years -- Chapter 13. Seagrass-oyster farmers interaction detected by eelgrass DNA analysis in Hinase area of the Seto Inland Sea, Japan -- Chapter 14. Fisheries Biology of Blue Sharks in Sagami Bay, Japan -- Part IV: Vulnerability of Coastal Ecosystems and Risk Assessment -- Chapter 15. Temperature and salinity changes in coastal waters of Western Europe: variability, trends and extreme events -- Chapter 16. Risk Based Consenting of Offshore Renewable Energy Projects (RICORE) -- Chapter 17. Does global warming favour the occurrence of recent blue mussel mortality events in France? -- Chapter 18. Integrated ecosystem management for exploited coastal ecosystem dynamics under oligotrophication and climate changes -- Chapter 19. Forty years of decline and 10 years of management plan: are European eels (Anguilla anguilla) recovering? -- Chapter 20. The management of Mediterranean coastal habitats: a plea for a socio-ecosystem-based approach.

Description / Table of Contents: Chapter1.Introduction: What Persists, what Changes -- Chapter2.The mountains -- Chapter3.It's getting warm down here -- Chapter4.Water towers of the west -- Chapter5.Trees, forests, and carbon -- Chapter6.Ecological disturbance -- Chapter7.Creatures great and small -- Chapter8.Extremes, Thresholds, Vulnerabilities -- Chapter9.Mountains and People in a Warming World.

Description / Table of Contents: Chapter 1. The Exhibition MARE PLASTICUM: Art and Science for the Environment -- Chapter 2. A Brief History of Plastics -- Chapter 3. Plastics and Microplastics: Impacts in the Marine Environment -- Chapter 4. The (Un)Natural History of the “Plastisphere”, A New Marine Ecosystem -- Chapter 5. Polarquest 2018 Expedition: Plastic Debris at 82°07’ North -- Chapter 6. The Impact of Marine Litter in Marine Protected Areas (MPAs) in the Mediterranean Sea: How Can We Protect MPAs? -- Chapter 7. Plastic in China: A Short History of a Crisis -- Chapter 8. "Down by the River": (Micro-) Plastic Pollution of Running Freshwaters with Special Emphasis on the Austrian Danube -- Chapter 9. Small Plastic Wastes in Soils: What Is Our Real Perception of the Problem? -- Chapter 10. Europe's Move Towards Plastic-Free Ocean -- Chapter 11. Plastic Pollution in the Oceans - A Systemic Analysis—Status Quo and Possible Sustainable Solutions -- Chapter 12. Toys for the Winter -- Chapter 13. "The Bottlenose Dolphin” (An Eco-comic).

Description / Table of Contents: Part 1. Litter dynamics: chapter 1. Litter Input (Arturo Elosegi & Jesús Pozo) -- Chapter 2. Leaf Retention (Arturo Elosegi) -- chapter 3. Manipulating Litter Retention in Streams (Michael Dobson) -- chapter 4. Coarse Benthic Organic Matter (Jesús Pozo & Arturo Elosegi) -- chapter5. Leaching (Felix Bärlocher) -- Chapter 6. Leaf Mass Loss Estimated by the Litter-Bag Technique (Felix Bärlocher) -- Chapter7. Determining Litter Mass Loss by the Plant Tagging Approach (Kevin A. Kuehn & Mark O. Gessner) -- Chapter 8. Wood Decomposition (Arturo Elosegi, Maite Arroita & Libe Solagaistua) -- Chapter9. Decomposition of Fine Particulate Organic Matter (Yoshimura Chihiro) -- Chapter10. Coarse Particulate Organic Matter Budgets (Jesús Pozo & Jon Molinero) -- Part 2. Chemical and Physical Leaf Properties. Chapter11. Total Phosphorus, Nitrogen, and Carbon in Leaf Litter (Mogens R. Flindt, Ana I. Lillebø, Javier Pérez & Verónica Ferreira) -- Chapter12. Total Protein (Mark O. Baerlocher) -- Chapter13. Free Amino Acids (Shawn D. Mansfield & Mark O. Baerlocher) -- chapter14. Determination of Total Carbohydrates (Shawn D. Mansfield) -- chapter15. Determination of Soluble Carbohydrates (Letitia da Ros, Faride Unda, Shawn D. Mansfield) -- Chapter16. Total Lipids (Mark O. Gessner & Paul T. M. Neumann) -- Chapter17. Polyunsaturated Fatty Acids in Decomposing Leaf Litter (Eric Von Elert) -- Chapter18. Total Phenolics (Felix Bärlocher & Manuel A.S. Graça) -- Chapter19. Radial Diffusion Assay for Tannins (Manuel A.S. Graça & Felix Bärlocher) -- Chapter20. Acid Butanol Assay to Determine Bulk Concentrations of Condensed Tannins (Mark O. Gessner & Daniel Steiner) -- Chapter21. Lignin and Cellulose (Mark O. Gessner) -- Chapter22. Physical Litter Properties: Leaf Toughness and Tensile Strength (Manuel A.S. Graça & Martin Zimmer) -- Part 3. Microbial Decomposers. Chapter23. Techniques for Handling Ingoldian Fungi (Enrique Descals) -- Chapter24. Maintenance of Aquatic Hyphomycete Cultures (Ludmila Marvanová) -- Chapter 25. An Illustrated Key to the Common Temperate Species of Aquatic Hyphomycetes (Vladislav Gulis, Ludmila Marvanová & Enrique Descals) -- Chapter26. Sporulation by Aquatic Hyphomycetes (Felix Bärlocher) -- Chapter 27. Ergosterol as a Measure of Fungal Biomass (Mark O. Gessner) -- Chapter 28. Fungal Growth Rates and Production (Keller Suberkropp, Mark O. Gessner & Kevin A. Kuehn) -- Chapter 29. Bacterial Abundance and Biomass Determination in Plant Litter by Epifluorescence Microscopy (Nanna Buesing & Mark O. Gessner) -- Chapter 30. Growth and Production of Litter-Associated Bacteria (Nanna Buesing, Mark O. Gessner & Kevin A. Kuehn) -- Chapter 31. Isolation of Cellulose-Degrading Bacteria (Jürgen Marxsen) -- Chapter 32. ATP as a Measure of Microbial Biomass (Manuela Abelho) -- Chapter 33. Respiration of Litter-Associated Microbes and Invertebrates (Manuel A.S. Graça & Manuela Abelho) -- Part 4. Molecular Microbial Community Analyses. Chapter34. Terminal Restriction Fragment Length Polymorphism (T-Rflp) to Estimate Fungal Diversity (Liliya G. Nikolcheva & Felix Bärlocher) -- Chapter 35. Denaturing Gradient Gel Electrophoresis (DGGE) to Estimate Fungal Diversity (Liliya G. Nikolcheva & Felix Bärlocher) -- Chapter36. Quantitative Real-Time PCR (qPCR) to Estimate Molecular Fungal Abundance (Christiane Baschien & J. Steffen C. Carl) -- Chapter 37. Metabarcoding of Litter-associated Fungi and Bacteria (Sofia Duarte, Christian Wurzbacher & Sahadevan Seena) -- Chapter 38. Identifying Active Members of Litter Fungal Communities by Precursor rRNA (Martina Štursová & Petr Baldrian) -- Chapter 39. Gene Expression Analysis of Litter-Associated Fungi Using RNA-Seq (Elizabeth C. Bourne, Paul R. Johnston, Elisabeth Funk & Michael T. Monaghan) -- Chapter 40. Metaproteomics of Litter-associated Fungi (Katharina M. Keiblinger & Katharina Riedel) -- Part 5. Enzymatic Capabilities. Chapter 41. Extractellular Fungal Hydrolytic Enzyme Activity (Shawn D. Mansfield) -- chapter 42. Cellulases (Martin Zimmer) -- Chapter 43. Viscosimetric Determination of Endocellulase Activity (Björn Hendel & Jürgen Marxsen) -- Chapter 44. Fluorometric Determination of The Activity of β-Glucosidase and other Extracellular Hydrolytic Enzymes (Björn Hendel & Jürgen Marxsen) -- Chapter 45. Pectin-degrading Enzymes: Polygalacturonase and Pectin Lyase (Keller Suberkropp) -- chapter 46. Lignin-degrading Enzymes: Phenoloxidase and Peroxidase (Björn Hendel, Robert L. Sinsabaugh & Jürgen Marxsen) -- Chapter 47. Phenol Oxidation (Martin Zimmer) -- Chapter 48. Proteinase Activity: Azocoll and Thin-layer Enzyme Assay (Manuel A.S. Graça & Felix Bärlocher) -- Part 6. Litter Consumers. Chapter 49. Processing of Aquatic Invertebrates Colonizing Decomposing Litter (John S. Richardson) -- chapter 50. Identifying Stream Invertebrates as Plant Litter Consumers (Luz Boyero, Richard G. Pearson, Ricardo J. Albariño, Marcos Callisto, Francisco Correa-Araneda, Andrea C. Encalada, Marcelo Moretti, Alonso Ramírez, April Sparkman, Christopher M. Swan, Catherine M. Yule & Manuel A.S. Graça) -- chapter 51. Shredder Feeding and Growth Rates (Manuel A.S. Graça & José M. González) -- chapter 52. Feeding Preferences (Cristina Canhoto, Manuel A.S. Graça & Felix Bärlocher) -- chapter 53. Energy Budget of Shredders (Manuel A.S. Graça) -- chapter 54. The Role of Shredders in Litter Dynamics at Stream Scale (José M. González & Manuel A.S. Graça) -- Part 7. Litter Manipulations. Chapter 55. Manipulation of Leaf Litter Stoichiometry (Julio Arce-Funck, Vincent Felten, Michael Danger) -- Chapter 56. Isotopic Labelling of Leaf-litter Nitrogen (Bernd Zeller, Severine Bienaimé & Etienne Dambrine) -- Chapter 57. Decomposition and Consumption Tablets (DECOTABSs) (Gea H. van Der Lee, Ellard R. Hunting, J. Arie Vonk & Michiel H.S. Kraak) -- chapter 58. Inoculation of Leaf Litter with Aquatic Hyphomycetes (Eric Chauvet) -- Part 8. Data Analyses. Chapter 59. A Primer for Statistical Analysis (Felix Bärlocher) -- Chapter 60. Determining Temperature-normalized Decomposition Rates (Mark O. Gessner & Frank Peeters) -- Chapter 61. Biodiversity Analysis (Felix Bärlocher) -- Chapter 62. A Bioinformatics Primer for the Analysis of Illumina MiSeq Data of Litter-associated Fungi and Bacteria (Sahadevan Seena, Sofia Duarte & Christian Wurzbacher) -- Chapter 63. A Primer for Meta-Analysis (Verónica Ferreira & Felix Bärlocher).

Description / Table of Contents: Executive Summary -- Overview and Purposes -- Key Message -- Chapter 1. State Of Forest And Rangeland Soils Research In The United States (Dan Binkley, Daniel D. Richter, Richard V. Pouyat, and Linda Geiser) -- Chapter 2. Soil Carbon (Erin Berryman, Jeff Hatten, Deborah S. Page-Dumroese, Kate Heckman, David D’Amore, Jennifer Puttere, Michael SanClements, Stephanie Connolly, Charles H. (Hobie) Perry, and Grant Domke) -- Chapter 3. Soils And Water (Mary Beth Adams, Vince Archer, Scott Bailey, Kevin McGuire, Chelcy Miniat, Dan Neary, Toby O’Geen, Pete Robichaud, and Mike Strobel) -- Chapter 4. Biogeochemical Cycling In Forest And Rangeland Soils Of The United States (Lindsey E. Rustad, Jennifer Knoepp, Daniel D. Richter, and Andrew Scott) -- Chapter 5. Forest And Rangeland Soil Biodiversity (Stephanie A. Yarwood, Elizabeth Bach, Matt Busse, Jane E. Smith, Mac A. Callaham, Jr., Chih-Han Chang, Taniya Roy Chowdhury, and Steven D. Warren) -- Chapter 6. Wetland And Hydric Soils (Carl Trettin, Randall Kolka, Anne Marsh, Sheel Bansal, Eric Lilleskov, Patrick Megonigal, Marla Stelk, Graeme Lockaby, David D’Amore, Richard MacKenzie, Brian Tangen, Rodney Chimner, and James Gries) -- Chapter 7. Urban Soils (Richard Pouyat, Susan Day, Sally Brown, Kirsten Schwarz, Richard Shaw, Katalin Szlavecz, Tara Trammell, and Ian Yesilonis) -- Chapter 8. Soil Management And Restoration (Mary Williams, Cara Farr, Deborah Page-Dumroese, Stephanie Connolly, and Eunice Padley) -- Chapter 9. Soil Mapping, Monitoring, And Assessment (Mark J. Kimsey, Larry E. Laing, Sarah Anderson, Jeff Bruggink, Steve Campbell, David Diamond, Grant Domke, James Gries, Scott Holub, Greg Nowacki, Deborah Page-Dumroese, Charles H. (Hobie) Perry, Lindsey Rustad, Kyle Stephens, and Robert Vaughan) -- Chapter 10. Challenges And Opportunities (Linda Geiser, Toral Patel-Weynand, Anne Marsh, Korena Mafune, and Daniel Vogt) -- Appendix A: Regional Summaries -- Appendix B: Soils Networks And Resources -- Appendix C: Summary Of Research Questions.