ALBERT

Description: Responses of animals exposed to microgravity during in-space experiments were observed via available video recording stored in the NASA Ames Life Sciences Data Archive. These documented observations of animal behavior, as well as the range and level of activities during spaceflight, demonstrate that weightlessness conditions and the extreme novelty of the surroundings may exert damaging psychological stresses on the inhabitants. In response to a recognized need for in-flight animals to improve their wellbeing we propose to reduce such stresses by shaping and interrelating structures and surroundings to satisfying vital physiological needs of inhabitants. A Rodent Habitat Hardware System (RHHS) based housing facility incorporating a tubing network system, to maintain and monitor rodent health environment with advanced accessories has been proposed. Placing mice in a tubing-configured environment creates more natural space-restricted nesting environment for rodents, thereby facilitating a more comfortable transition to living in microgravity. A sectional tubing structure of the RHHS environment will be more beneficial under microgravity conditions than the provision of a larger space area that is currently utilized. The new tubing configuration was found suitable for further incorporation of innovative monitoring technology and accessories in the animal holding habitat unit which allow to monitor in real-time monitoring of valuable health related biological parameters under weightlessness environment of spaceflight.

Description: We report the identification of a bright hard X-ray source dominating the M31 bulge above 25 keV from a simultaneous NuSTAR-Swift observation. We find that this source is the counterpart to Swift J0042.6+4112, which was previously detected in the Swift BAT All-Sky Hard X-Ray Survey. This Swift BAT source had been suggested to be the combined emission from a number of point sources; our new observations have identified a single X-ray source from 0.5 to 50 keV as the counterpart for the first time. In the 0.5-10 keV band, the source had been classified as an X-ray Binary candidate in various Chandra and XMM-Newton studies; however, since it was not clearly associated with Swift J0042.6+4112, the previous E is less than 10keVobservations did not generate much attention. This source has a spectrum with a soft X-ray excess (kT approximately equal to 0.2 keV) plus a hard spectrum with a power law of gamma approximately equal to 1 and a cutoff around 15-20 keV, typical of the spectral characteristics of accreting pulsars. Unfortunately, any potential pulsation was undetected in the NuSTAR data, possibly due to insufficient photon statistics. The existing deep HST (Hubble Space Telescope) images exclude high-mass (greater than 3 times the radius of the moon) donors at the location of this source. The best interpretation for the nature of this source is an X-ray pulsar with an intermediate-mass (less than 3 times the radius of the moon M) companion or a symbiotic X-ray binary. We discuss other possibilities in more detail.

Description: Hot dust-obscured galaxies (hot DOGs), selected from Wide-Field Infrared Survey Explorer's all-sky infrared survey, host some of the most powerful active galactic nuclei known and may represent an important stage in the evolution of galaxies. Most known hot DOGs are located at z 〉 1.5, due in part to a strong bias against identifying them at lower redshift related to the selection criteria. We present a new selection method that identifies 153 hot DOG candidates at z approx. 1, where they are significantly brighter and easier to study. We validate this approach by measuring a redshift z = 1.009 and finding a spectral energy distribution similar to that of higher-redshift hot DOGs for one of these objects, WISE J1036+0449 (L(sub BOL) approx. = 8 x 10(exp 46) erg/s). We find evidence of a broadened component in Mg II, which would imply a black hole mass of M(BH) approx. = 2 x 10(exp 8) Stellar Mass and an Eddington ratio of lambda(sub Edd) approx. = 2.7. WISE J1036+0449 is the first hot DOG detected by the Nuclear Spectroscopic Telescope Array, and observations show that the source is heavily obscured, with a column density of N(sub H) approx. = (2-15) x 10(exp 23)/sq cm. The source has an intrinsic 2-10 keV luminosity of approx. 6 x 10(exp 44) erg/s, a value significantly lower than that expected from the mid-infrared X-ray correlation. We also find that other hot DOGs observed by X-ray facilities show a similar deficiency of X-ray flux. We discuss the origin of the X-ray weakness and the absorption properties of hot DOGs. Hot DOGs at z 〈 or approx. 1 could be excellent laboratories to probe the characteristics of the accretion flow and of the X-ray emitting plasma at extreme values of the Eddington ratio.

Description: We report the discovery of a binary composed of two brown dwarfs, based on the analysis of the micro lensing event OGLE-2016-BLG-1469. Thanks to the detection of both finite-source and micro lens-parallax effects, we are able to measure both the masses M(sub 1) ~ 0.05 Solar Mass and M(sub 2) ~ 0.01 Solar Mass, and the distance D(sub L) ~ 4.5 kpc, as well as the projected separation a(sub perpendicular) ~ 0.33 au. This is the third brown-dwarf binary detected using the micro lensing method, demonstrating the usefulness of micro lensing in detecting field brown-dwarf binaries with separations of less than 1 au.

Description: We present the result of microlensing event MOA-2016-BLG-290, which received observations from the two-wheel Kepler (K2), Spitzer, as well as ground-based observatories. A joint analysis of data from K2 and the ground leads to two degenerate solutions of the lens mass and distance. This degeneracy is effectively broken once the (partial) Spitzer light curve is included. Altogether, the lens is found to be an extremely low-mass star or brown dwarf (77(sup +34)(sub -23) M(sub J)) located in the Galactic bulge (6.8 0.4 kpc). MOA-2016-BLG-290 is the first microlensing event for which we have signals from three well-separated (~1 au) locations. It demonstrates the power of two-satellite microlensing experiment in reducing the ambiguity of lens properties, as pointed out independently by S. Refsdal and A. Gould several decades ago.

Description: A coupling between geomagnetic activity and the human nervous system's function was identified by virtue of continuous monitoring of heart rate variability (HRV) and the time-varying geomagnetic field over a 31-day period in a group of 10 individuals who went about their normal day-to-day lives. A time series correlation analysis identified a response of the group's autonomic nervous systems to various dynamic changes in the solar, cosmic ray, and ambient magnetic field. Correlation coefficients and p values were calculated between the HRV variables and environmental measures during three distinct time periods of environmental activity. There were significant correlations between the group's HRV and solar wind speed, Kp, Ap, solar radio flux, cosmic ray counts, Schumann resonance power, and the total variations in the magnetic field. In addition, the time series data were time synchronized and normalized, after which all circadian rhythms were removed. It was found that the participants' HRV rhythms synchronized across the 31-day period at a period of approximately 2.5 days, even though all participants were in separate locations. Overall, this suggests that daily autonomic nervous system activity not only responds to changes in solar and geomagnetic activity, but is synchronized with the time-varying magnetic fields associated with geomagnetic field-line resonances and Schumann resonances.

Description: The detrimental effects of mechanical unloading in microgravity, including the musculo-skeletal system, are well documented. However, the effects of mechanical unloading on joint health and the interaction between bone and cartilage specifically, are less well known. Our ongoing studies with the mouse bone model have identified the failure of normal stem cell-based tissue regeneration, in addition to tissue degeneration, as a significant concern for long-duration spaceflight, especially in the mesenchymal and hematopoietic tissue lineages. Furthermore, we have identified the cell cycle arrest molecule, CDKN1ap21, as specifically up-regulated during spaceflight exposure and localized to osteoprecursors on the bone surface and chondroprogenitors in articular cartilage that are both required for normal tissue regeneration. The 30-day BionM1 and 37-day Rodent Research 1 (RR1) missions enabled the possibility of studying these effects in long-duration microgravity experiments. We hypothesized that the inhibition of stem cell-based tissue regeneration in short-duration spaceflight would continue during long-duration spaceflight resulting in significant tissue alterations and we specifically studied the hip joint (pelvis and proximal femur) to elucidate these effects. To test this hypothesis we analyzed bone and bone marrow stem cells using techniques including high-resolution Microcomputed Tomography (MicroCT), in-vivo differentiation and migration assays, and whole transcriptome expression profiling. We found that exposure to spaceflight for 30 days results in a significant decrease in bone volume fraction (-31), trabecular thickness (-14) and trabecular number (-20). Similar decrements in bone volume fraction (-27), trabecular number (-13) and trabecular thickness (-17) were found in female mice exposed to 37 days spaceflight. Furthermore, high-resolution MicroCT and immunohistochemical analysis of spaceflight tissues revealed a severe disruption of the epiphyseal boundary, resulting in endochondral ossification of the femoral head and perforation of articular cartilage by bone. This suggests that spaceflight in microgravity may cause rapid induction of an aging-like phenotype with signs of osteoarthritic disease in the hip joint. Microarray analysis also revealed that the top pathways altered during spaceflight include activation of matrix metalloproteinases, oxidative stress signaling and inflammation in both whole bone tissue and isolated bone marrow stem cells. In conclusion, the observed inhibition of stem cell-based tissue regeneration persists during long-duration spaceflight. Furthermore, spaceflight mice exhibit disruption of the epiphyseal boundary and endochondral ossification of the femoral head, and an inhibition of stem cell based tissue regeneration, which, taken together, may indicate onset of an accelerated aging phenotype with signs of osteoarthritic disease.

Description: Broad tissue degeneration and the failure of normal tissue regenerative processes in microgravity because of mechanical unloading are increasing concerns for sustaining life in space as the duration of future flight missions increases. Work in our laboratory has identified normal adult stem cell-based tissue regenerative processes, such as the formation of new bone, cartilage, and immune cells, as being particularly sensitive to the stresses of mechanical unloading in microgravity. Our studies have also identified the inhibition of differentiation of marrow mesenchymal stem cells and activation of CDKN1ap21-mediated cell cycle arrest in proliferative osteoprecursor cells on the bone surface as potential mechanisms for spaceflight-induced skeletal changes. This finding, in combination with the role of CDKN1ap21 as a suppressor of mammalian tissue regeneration, suggests that this gene could be responsible for suppressing stem cell-based tissue regeneration in response to disuse. In this work, we hypothesized that CDKN1ap21 regulates regenerative bone formation in response to alterations in mechanical load and tested this hypothesis by studying the skeletal phenotype and stem cell regenerative ability of juvenile (4-11 weeks old) and adult (18 weeks-12 months old) p21 (--) knockout (KO) mice. Additionally, we analyzed bone micro-architectural properties, bone formation rates and differentiation capacity of bone marrow stem cells (BMSCs) from male and female KO mice exposed to hindlimb unloading (HU) for 15-30 days. We found that juvenile KO mice exhibited increased femoral trabecular and cortical bone formation, whilst three-point bending of the tibias from KO mice showed decreased bone stiffness. Conversely, adult KO mice exhibited no significant differences in micro-architectural properties compared to WT (wild-type) but woven bone structure was indicative of rapid bone remodeling. Furthermore, cortical bone properties showed similar characteristics to aged bone, including increased cross-sectional area and perimeter, whilst three-point bending showed increased stiffness and toughness. Interestingly, in-vitro, KO mice exhibited increased differentiation and mineralized nodule formation in osteoblastogenesis assays compared to WT. Preliminary results from CDKN1ap21 KO mice subjected to HU suggest altered sensitivity to mechanical unloading resulting in decreased cortical thickness compared to WT mice. However, KO mice subjected to short and long-duration HU show increased in-vitro differentiation potential of BMSCs to from form mature, mineral-forming osteoblasts, indicating maintenance of regenerative potential. Analysis of bone formation rates, cell proliferation rates and key genes of interest are currently underway. These results indicate a novel role for CDKN1ap21 in load-dependent osteoprogenitor proliferation and differentiation and that deletion of CDKN1ap21 results in an age-dependent release of osteoblast proliferation inhibition and increased bone formation and turnover.

Description: A large variety of organic compounds of astrobiological and prebiotic interest have been detected in carbonaceous meteorites. These include amino acids, carboxylic acids, amphiphiles, functionalized nitrogen heterocycles such as nucleobases, functionalized polycylic aromatic hydrocarbons such as quinones, and sugar derivatives. The sugar derivatives identified in the Murchison and Murray meteorites are mainly sugar alcohols and sugar acids, and only the smallest sugar (dihydroxyacetone) has been detected. The presence of such a variety of organics in meteorites strongly suggests that molecules essential to life can form abiotically under astrophysical conditions. This hypothesis is further supported by laboratory studies in which astrophysical ice analogs (mixtures of H2O, CO, CO2, CH3OH, CH4, NH3, etc.) are subjected to ultraviolet (UV) irradiation at low temperature (〈15 K) to simulate cold interstellar environments. These studies show that the organic residues recovered at room temperature after irradiation contain amino acids, amphiphiles, nucleobases, sugar derivatives, as well as other complex organic compounds. The finding of such compounds under plausible interstellar conditions is consistent with the presence of organic compounds in meteorites. Until very recently, no systematic search for the presence of sugar derivatives in laboratory residues had been carried out. The detection of ribose, the sugar constituent of RNA in all living systems, as well as other sugars, sugar alcohols, and sugar acids have been recently reported in one organic residue produced from the UV irradiation of an H2O:CH3OH:NH3 (10:3.5:1) ice mixture at 80 K. In this work, we present a detailed study of organic residues produced from the UV irradiation ice mixtures of several starting compositions (containing H2O, CH3OH, CO, CO2, and/or NH3) at 〈15 K for their sugar derivative content. Our results confirm the presence of all 3C5C sugar alcohols, several 3C5C sugars, and all 3C4C sugar acids (in decreasing order of abundances) in the residues. The higher abundances of sugar alcohols in these residues suggest a pathway in which sugar alcohols are formed first, while the formation of sugars and sugar acids require more steps. Finally, our results are compared with the detection of sugars derivatives in primitive meteorites.

Description: In support of air revitalization system sorbent selection for future space missions, Ames Research Center (ARC) has performed CO2 capacity tests on various sorbents to complement structural strength tests from Marshall Space Flight Center (MSFC). The materials of interest are: Grace Davison Grade 544 13x, Honeywell UOP APG III, VSA-10, BASF 13x, and Grace Davison Grade 522 5A. Each sorbents CO2 capacity was measured using a Micromeritics ASAP 2020 Physisorption Volumetric Analysis machine to produce 0C, 10C, 25C, 50C, and 75C isotherms. These datasets were then extrapolated using Langmuir 3-Site and Toth isotherm models to compare with previously measured capacity data from MSFC using a thermogravimetric analysis approach. The modeling and extrapolation from ARC data correlated well with data measured at MSFC.

Description: Gravitational wave searches to date have largely focused on non-precessing systems. Including precession effects greatly increases the number of templates to be searched over. This leads to a corresponding increase in the computational cost and can increase the false alarm rate of a realistic search. On the other hand, there might be astrophysical systems that are entirely missed by non-precessing searches. In this paper we consider the problem of constructing a template bank using stochastic methods for neutron star-black hole binaries allowing for precession, but with the restrictions that the total angular momentum of the binary is pointing toward the detector and that the neutron star spin is negligible relative to that of the black hole. We quantify the number of templates required for the search, and we explicitly construct the template bank. We show that despite the large number of templates, stochastic methods can be adapted to solve the problem. We quantify the parameter space region over which the non-precessing search might miss signals.

Description: Limits and guidelines are set on microbial counts in produce to protect the consumer. Different agencies make specifications, which constitute when a product becomes unsafe for human consumption. Producers design their procedures to comply with the limits, but they are responsible creating their own internal standards. The limits and guidelines are summarized here to be applied to assess the microbial safety of the NASA Veggie Program.

Description: As the world's space agencies and commercial entities continue to expand beyond Low Earth Orbit (LEO), novel approaches to carry out biomedical experiments with animals are required to address the challenge of adaptation to space flight and new planetary environments. The extended time and distance of space travel along with reduced involvement of Earth-based mission support increases the cumulative impact of the risks encountered in space. To respond to these challenges, it becomes increasingly important to develop the capability to manage an organism's self-regulatory control system, which would enable survival in extraterrestrial environments. To significantly reduce the risk to animals on future long duration space missions, we propose the use of metabolically flexible animal models as "pathfinders," which are capable of tolerating the environmental extremes exhibited in spaceflight, including altered gravity, exposure to space radiation, chemically reactive planetary environments and temperature extremes. In this report we survey several of the pivotal metabolic flexibility studies and discuss the importance of utilizing animal models with metabolic flexibility with particular attention given to the ability to suppress the organism's metabolism in spaceflight experiments beyond LEO. The presented analysis demonstrates the adjuvant benefits of these factors to minimize damage caused by exposure to spaceflight and extreme planetary environments. Examples of microorganisms and animal models with dormancy capabilities suitable for space research are considered in the context of their survivability under hostile or deadly environments outside of Earth. Potential steps toward implementation of metabolic control technology in spaceflight architecture and its benefits for animal experiments and manned space exploration missions are discussed.

Description: The Q1Q17 DR25 TCERT Vetting Reports are a collection of plots and diagnostics used by the Threshold Crossing Event Review Team (TCERT) to evaluate threshold crossing events (TCEs). While designation of Kepler Objects of Interest (KOIs) and classification of them as Planet Candidates (PCs) or False Positives (FPs) is completely automated via a robotic vetting procedure (the Robovetter) for the Q1Q17 DR25 planet catalog, as described in Thompson et al. (2017), these reports help to visualize the metrics used by the Robovetter and evaluate those robotic decisions for individual objects. For each Q1Q17 DR25 TCE, these reports include the following products: (a) the DV one-page summary, (b) selected pertinent diagnostics and plots from the full DV report, and (c) additional plots and diagnostics not included in the full DV report, including an alternate means of data detrending.

Description: We report the discovery and the analysis of the planetary microlensing event, OGLE-2013-BLG-1761. There are some degenerate solutions in this event because the planetary anomaly is only sparsely sampled. However, the detailed light curve analysis ruled out all stellar binary models and shows the lens to be a planetary system. There is the so-called close wide degeneracy in the solutions with the planet host mass ratio of q approx.(7.0+/-2.0) x 10(exp -3) and q approx.(8.1+/-2.6) x 10(exp -3) with the projected separation in Einstein radius units of s = 0.95 (close) and s = 1.18(wide), respectively. The microlens parallax effect is not detected, but the finite source effect is detected. Our Bayesian analysis indicates that the lens system is located -D(sub L) = 6.9(+ 1.0 -1.2)kpc away from us and the host star is an M/K dwarf with amass of M(sub L) = 0.33(+ 0.32- 1.9)Stellar Mass orbited by a super-Jupiter mass planet with a mass of m(sub p) = 2.7(+ 2.5 - 1.5) M(sub Jup) at the projected separation of a(sub l) = 1.8(+ 0.5 -0.5)au. The preference of the large lens distance in the Bayesian analysis is due to the relatively large observed source star radius. The distance and other physical parameters may be constrained by the future high-resolution imaging by large ground telescopes or HST. If the estimated lens distance is correct, then this planet provides another sample for testing the claimed deficit of planets in the Galactic bulge.

Description: Exploration of the solar system is constrained by the cost of moving mass off Earth. Producing materials in situ will reduce the mass that must be delivered from earth. CO2 is abundant on Mars and manned spacecraft. On the ISS, NASA reacts excess CO2 with H2 to generate CH4 and H2O using the Sabatier System. The resulting water is recovered into the ISS, but the methane is vented to space. Thus, there is a capability need for systems that convert methane into valuable materials. Methanotrophic bacteria consume methane but these are poor synthetic biology platforms. Thus, there is a knowledge gap in utilizing methane in a robust and flexible synthetic biology platform. The yeast Pichia pastoris is a refined microbial factory that is used widely by industry because it efficiently secretes products. Pichia could produce a variety of useful products in space. Pichia does not consume methane but robustly consumes methanol, which is one enzymatic step removed from methane. Our goal is to engineer Pichia to consume methane thereby creating a powerful methane-consuming microbial factory.

Description: So you want to conduct human spaceflight research aboard the International Space Station (ISS)? Once your spaceflight research aboard the ISS is proposal is funded.... the real work begins. Because resources are so limited for ISS research, it is necessary to maximize the work being done, while at the same time, minimizing the resources spent. Astronauts may be presented with over 30 human research experiments and select, on average approximately 15 in which to participate. In order to conduct this many studies, ISSMP uses the study requirements provided by the principle investigator to integrate all of this work into the astronauts' complement. The most important thing for investigators to convey to the ISSMP team is their RESEARCH REQUIREMENTS. Requirements are captured in the Experiment document. This document is the official record of how, what, where and when data will be collected. One common mistake that investigators make is not taking this document seriously, but when push comes to shove, if a research requirement is not in this document....it will not get done. The research requirements are then integrated to form a complement of research for each astronaut. What do we mean by integration? Many experiments have overlapping requirements; blood draws, behavioral surveys, heart rate measurement. Where possible, these measures are combined to reduce redundancy and save crew time. Investigators can access these data via data sharing agreements. More examples of how ISS research is integrated will be presented. There are additional limitations commonly associated with human spaceflight research that will also be discussed. Large/heavy hardware, invasive procedures, and toxic reagents are extremely difficult to implement on the ISS. There are strict limits placed on the amount of blood that can be drawn from crew members during (and immediately after) spaceflight. These limits are based on 30-day rolling accumulations. We have recently had to start restricting studies due to this limit. The NASA Human Research Program (HRP) provides extensive support, via ISSMP, to help investigators cope with all of the intricacies of conducting human spaceflight research. This presentation will help you take the best advantage of that support.

Description: Spectrum is a multispectral fluorescence imager designed for capturing in vivo genetic expression in a variety of biological organisms, providing a capability that does not currently exist on the International Space Station (ISS). Researching organisms that have been transformed with in vivo reporter genes ligated with fluorescent proteins allows the scientific community to further understand the fundamental biological responses of these organisms when subjected to space environments. Model organisms that may utilize multispectral imaging on the ISS include unicellular organisms (e.g. Saccharomyces cerevisiae), plants (e.g. Arabidopsis thaliana), and invertebrates (e.g. Caenorhabditis elegans).

Description: Continued space bioscience research onboard the International Space Station (ISS) and future long-duration flight missions to the Moon or Mars will require the ability to conduct on-orbit molecular analysis of biological samples independently from Earth. In the last year two new molecular analytic technologies have been installed and the technologies demonstrated onboard the ISS: The Sample Prep Module (SPM) WetLab-2 (WL2) qRT-PCR toolbox and the Oxford Nanopore MinIon Biomolecule Sequencer. Here we describe protocol development and integration into existing ISS technology for end-to-end on-orbit biological sample processing and molecular analysis with real time results generated utilizing only field offline analytic software. For this experiment we isolated primary cells from bone marrow flushes of wild type B6129SF2 mice (Jackson Labs) long bones. The cell isolate was then processed using the SPM to produce total 147nanograms of RNA. The total RNA was purified to only messenger RNA (mRNA) and transferred to Smartcycler Thermocycle ISS kit consumable tube using Eppendorf gel loading pipette tips for further processing. Complementary first strand cDNA was synthesized using OLIGO dT priming followed by addition of SuperScript II Reverse Transcriptase and thermal cycling as per manufacturers instruction. All thermal cycling was conducted using the ISS WetLab-2 Cephid Smarcycler real time thermal cycler. Our protocol takes advantage of mRNAs native poly(A) tail, synthesized in vivo to protect the mRNA from degradation by endonucleases, to eliminate end-prep for adapter ligation. The adapted library is purified using MyOne C1 Streptavidin beads before elution in buffer. The pre-sequencing library is diluted in the loading buffer and injected into the MinIon sample port, drawn into the nanopore window by capillary action, and sequenced using the MinKnown software with local basecalling. The sequencing read produced 34.5 million events and local basecalling produced 117,301 successful reads. NCBI Blast of the data for the mouse genome resulted in 2,462 successful nucleotide collection matches (gene sequences) exceeding 70 homology. These results demonstrate the viability of this novel flight ready end-to-end sample analytic methodology and provide a real time homolog for flight experimentation utilizing supply kits and technologies that have already been demonstrated on ISS.

Description: System testing of the Carbon Dioxide Removal and Compression System (CRCS) has revealed that sufficient CO2 removal capability was not achieved with the designed system. Subsystem component analysis of the zeolite bed revealed that the sorbent material suffered significant degradation and CO2 loading capacity loss. In an effort to find the root cause of this degradation, various factors were investigated to try to reproduce the observed performance loss. These factors included contamination by vacuum pump oil, o-ring vacuum grease, loadingunloading procedures, and operations. This paper details the experiments that were performed and their results.

Description: Spaceflight environments and their associated conditions, such as microgravity and space radiation, cause many biological functions formerly considered to be standard to behave in nonstandard ways. Exposure to microgravity has shown to induce deleterious effects in stem cell-based tissue regeneration, leading to immune system and healing response impairments as well as muscle and bone density loss. Such risks must be mitigated in order for long-term human space exploration to proceed. Thus, our work seeks to explore mechanisms of stem cell-based tissue regeneration that experience changes in spaceflight environments. Cellular senescence is a process of inducing cell cycle arrest that can be initiated by various stimuli. This function is influenced by two major pathways, controlled by p53 and pRB tumor suppressor proteins. p53 activity targets the cyclin-dependent kinase inhibitor gene p21Cdkn1a in osteogenic cell cycle arrest. Under conditions of mechanical unloading, stem cell-based tissue regeneration has shown to be decreased in both proliferation and differentiation, as many cells are arrested in progenitor states. p21 has shown upregulation in expression under conditions of microgravity, suggesting its role in regenerative bone formation arrest in space. p21 levels are found to be elevated independent of p53, suggesting a decrease in proliferation and regeneration without apoptosis, but rather through cell cycle arrest alone. Thus, we hypothesize that p21 is a mediator of cellular senescence in bone marrow stem cells. Culturing of bone marrow stem cells from wild type and p21 knockout mice under osteoblastogenic conditions will be completed to explore the role of p21Cdkn1a in stem cell proliferation and maturation. We believe that decreases in somatic stem cell differentiation may occur after spaceflight due to signal pathway alterations that result in downstream inhibition of genes involved in differentiation, preventing tissue from repairing and regenerating normally.

Description: The ends of human chromosomes contain telomeres, or tandem arrays of repeating DNA sequences capped by multiple associated proteins that protect chromosomal ends from degradation. Telomeres function to preserve genomic stability by preventing natural chromosomal ends from being recognized as broken DNA double-strand breaks and triggering inappropriate DNA damage responses. Mounting evidence shows telomere length is an inherited trait that decreases with cellular division and normal aging. In addition, telomere length also appears to be influenced by other factors such as cellular oxidative stress, radiation and mechanical unloading of tissues as in microgravity. To measure these potential effects of the space environment on telomere lengths and cellular aging and regenerative potential we developed a novel telomere measurement approach based on nanopore sequencing of PCR amplified bar-coded chromosome termini. Specifically, telomeres can be directly enriched using barcode sequences ligated to the end of a free end- repaired telomere using the WetLab-2 facility SmartCycler on ISS. Prior to the ligation and amplification protocol a proteinase K digestion of capping proteins followed by a single 95-degree C heat denaturation of the protease is included. After digestion and bar-code ligation, PCR amplification will initiate with the ligated barcoded sequence, suppressing amplification of intra-genomic fragments and resulting in long read barcoded telomere amplicons including the nanopore motor protein sequences. Purified PCR amplicons are then used for nanopore sequencing library generation by simple addition of motor proteins and sequencing library is loaded into the MinION nanopore DNA-sequencer. Amplicon sequence reads from the nanopore device can be base-called quickly on ISS due to barcoding ligation and subsequent PCR amplification enhancing the telomere sequence resolution. If successfully implemented on ISS this technique will provide a novel means of measuring regenerative ability of somatic stem cells in astronauts, and of determining whether spaceflight in microgravity alters their telomere lengths and causes premature cellular aging.

Description: While supernova remnants (SNRs) are widely thought to be powerful cosmic-ray accelerators, indirect evidence comes from a small number of well-studied cases. Here we systematically determine the gamma-ray emission detected by the Fermi Large Area Telescope (LAT) from all known Galactic SNRs, disentangling them from the sea of cosmic-ray generated photons in the Galactic plane. Using LAT data we have characterized the 1-100 GeV emission in 279 regions containing SNRs, accounting for systematic uncertainties caused by source misattribution and instrumental response. We classified 30 sources as SNRs, using spatial overlap with the radio emission position. For all the remaining regions we evaluated upper limits on SNRs' emission. In the First Fermi-LAT SNR Catalog there is a study of the common characteristics of these SNRs, such as comparisons between GeV, radio and TeV quantities. We show that previously satisfactory models of SNRs' GeV emission no longer adequately describe the data. To address the question of cosmic ray (CR) origins, we also examine the SNRs' maximal CR contribution assuming the GeV emission arises solely from proton interactions. Improved breadth and quality of multiwavelength (MW) data, including distances and local densities, and more, higher resolution gamma-ray data with correspondingly improved Galactic diffuse models will strengthen this constraint.

Description: Mid-infrared spectra of amorphous and crystalline acetone are presented along with measurements of the refractive index and density for both forms of the compound. Infrared band strengths are reported for the first time for amorphous and crystalline acetone, along with IR optical constants. Vapor pressures and a sublimation enthalpy for crystalline acetone also are reported. Positions of (sup 13) C-labeled acetone are measured. Band strengths are compared to gas-phase values and to the results of a density-functional calculation. A 73 percent error in previous work is identified and corrected.

Description: We find evidence for a strong thermal inversion in the dayside atmosphere of the highly irradiated hot Jupiter WASP-18b (equatorial temperature equals 2411 degrees Kelvin, mass equals 10.3 times the mass of Jupiter) based on emission spectroscopy from Hubble Space Telescope secondary eclipse observations and Spitzer eclipse photometry. We demonstrate a lack of water vapor in either absorption or emission at 1.4 microns. However, we infer emission at 4.5 microns and absorption at 1.6 microns that we attribute to CO, as well as a non-detection of all other relevant species (e.g., TiO, VO). The most probable atmospheric retrieval solution indicates a C/O ratio of 1 and a high metallicity (C/H equals 283 from plus 395 to minus 138 times solar). The derived composition and temperature/pressure profile suggest that WASP-18b is the first example of both a planet with a non-oxide driven thermal inversion and a planet with an atmospheric metallicity inconsistent with that predicted for Jupiter-mass planets at greater than 2 sigma. Future observations are necessary to confirm the unusual planetary properties implied by these results.

Description: We announce the discovery of KELT-16b, a highly irradiated, ultra-short period hot Jupiter transiting the relatively bright (visual magnitude equals 11.7) star TYC 2688-1839-1/KELT-16. A global analysis of the system shows KELT-16 to be an F7V star with effective temperature equal to 6236 plus or minus 54 degrees Kelvin, log g (sub asterisk) equal to 4.253 from plus 0.031 to minus 0.036, [Fe/H] equal to minus 0.002 from plus 0.086 to minus 0.085, mass (sub asterisk) equal to 1.211 from plus 0.043 to minus 0.046 times the solar mass, and radius (sub asterisk) equal to 1.360 from plus 0.064 o minus 0.053 times the solar radius. The planet is a relatively high-mass inflated gas giant with planetary mass equal to 2.75 from plus 0.016 to minus 0.15 times Jupiter's mass, planetary radius equal to 1.415 from plus 0.084 to minus 0.067 times Jupiter's radius, density planetary rho equal to 1.20 plus or minus 0.18 grams per cubic centimeter, surface gravity, log planetary gravity equal to 3.530 from plus 0.042 to minus 0.049, and equatorial temperature equal to 2453 from plus 55 to minus 47 degrees Kelvin. The best-fitting linear ephemeris is T(sub C) equal to 22457247.24791 plus or minus 0.00019 BJD (sub TDB) and P equal to 0.9689951 plus or minus 0.0000024 day. KELT-16b joins WASP-18b, -19b, -43b, -103b, and HATS-18b as the only giant transiting planets with periodicity P less than 1 day. Its ultra-short period and high irradiation make it a benchmark target for atmospheric studies by the Hubble Space Telescope, Spitzer, and eventually the James Webb Space Telescope. For example, as a hotter, higher-mass analog of WASP-43b, KELT-16b may feature an atmospheric temperature-pressure inversion and day-to-night temperature swing extreme enough for TiO to rain out at the terminator. KELT-16b could also join WASP-43b in extending tests of the observed mass-metallicity relation of the solar system gas giants to higher masses. KELT-16b currently orbits at a mere approximately 1.7 Roche radii from its host star, and could be tidally disrupted in as little as a few times 10 (sup 5) years (for a stellar tidal quality factor of Q (sup prime) (sub asterisk) equal to 10 (sup 5). Finally, the likely existence of a widely separated bound stellar companion in the KELT-16 system makes it possible that Kozai-Lidov (KL) oscillations played a role in driving KELT-16b inward to its current precarious orbit.

Description: The NASA K2 (Kepler-2) mission uses photometry to find planets transiting stars of various types. M dwarfs are of high interest since they host more short-period planets than any other type of main-sequence star and transiting planets around M dwarfs have deeper transits compared to other main-sequence stars. In this paper, we present stellar parameters from K and M dwarfs hosting transiting planet candidates discovered by our team. Using the SOFI (Son OF Isaac - ESA's earlier, similar instrument) spectrograph on the European Southern Observatory's New Technology Telescope, we obtained R approximately equal to 1000 J-, H-, and K-band (0.95-2.52 micron) spectra of 34 late-type K2 planet and candidate planet host systems and 12 bright K4-M5 dwarfs with interferometrically measured radii and effective temperatures. Out of our 34 late-type K2 targets, we identify 27 of these stars as M dwarfs. We measure equivalent widths of spectral features, derive calibration relations using stars with interferometric measurements, and estimate stellar radii, effective temperatures, masses, and luminosities for the K2 planet hosts. Our calibrations provide radii and temperatures with median uncertainties of 0.059 solar radii (16.09 percent) and 160 degrees Kelvin (4.33 percent), respectively. We then reassess the radii and equilibrium temperatures of known and candidate planets based on our spectroscopically derived stellar parameters. Since a planet's radius and equilibrium temperature depend on the parameters of its host star, our study provides more precise planetary parameters for planets and candidates orbiting late-type stars observed with K2. We find a median planet radius and an equilibrium temperature of approximately 3 solar radii and 500 degrees Kelvin, respectively, with several systems (K2-18b and K2-72e) receiving near-Earth-like levels of incident irradiation.

Description: The redshifted 21 cm monopole is expected to be a powerful probe of the epoch of the first stars and galaxies(10 less than z less than 35). The global 21 cm signal is sensitive to the thermal and ionization state of hydrogen gas and thusprovides a tracer of sources of energetic photonsprimarily hot stars and accreting black holeswhich ionize andheat the high redshift intergalactic medium (IGM). This paper presents a strategy for observations of the globalspectrum with a realizable instrument placed in a low-altitude lunar orbit, performing night-time 40120 MHzspectral observations, while on the farside to avoid terrestrial radio frequency interference, ionospheric corruption,and solar radio emissions. The frequency structure, uniformity over large scales, and unpolarized state of theredshifted 21 cm spectrum are distinct from the spectrally featureless, spatially varying, and polarized emissionfrom the bright foregrounds. This allows a clean separation between the primordial signal and foregrounds. Forsignal extraction, we model the foreground, instrument, and 21 cm spectrum with eigenmodes calculated viaSingular Value Decomposition analyses. Using a Markov Chain Monte Carlo algorithm to explore the parameterspace defined by the coefficients associated with these modes, we illustrate how the spectrum can be measured andhow astrophysical parameters (e.g., IGM properties, first star characteristics) can be constrained in the presence offoregrounds using the Dark Ages Radio Explorer (DARE).

Description: We present near-infrared high-precision photometry for eight transiting hot Jupiters observed during their predicted secondary eclipses. Our observations were carried out using the staring mode of the WIRCam instrument on the Canada-France-Hawaii Telescope (CFHT). We present the observing strategies and data reduction methods which delivered time series photometry with statistical photometric precision as low as 0.11%. We performed a Bayesian analysis to model the eclipse parameters and systematics simultaneously. The measured planet-to-star flux ratios allowed us to constrain the thermal emission from the day side of these hot Jupiters, as we derived the planet brightness temperatures. Our results combined with previously observed eclipses reveal an excess in the brightness temperatures relative to the blackbody prediction for the equilibrium temperatures of the planets for a wide range of heat redistribution factors. We find a trend that this excess appears to be larger for planets with lower equilibrium temperatures. This may imply some additional sources of radiation, such as reflected light from the host star and/or thermal emission from residual internal heat from the formation of the planet.

Description: The current explosion in detection and characterization of thousands of extrasolar planets from the Kepler mission, the Hubble Space Telescope, and large ground-based telescopes opens a new era in searches for Earth-analog exoplanets with conditions suitable for sustaining life. As more Earth-sized exoplanets are detected in the near future, we will soon have an opportunity to identify habitale worlds. Which atmospheric biosignature gases from habitable planets can be detected with our current capabilities? The detection of the common biosignatures from nitrogen-oxygen rich terrestrial-type exoplanets including molecular oxygen (O2), ozone (O3), water vapor (H2O), carbon dioxide (CO2), nitrous oxide (N2O), and methane (CH4) requires days of integration time with largest space telescopes, and thus are very challenging for current instruments. In this paper we propose to use the powerful emission from rotational-vibrational bands of nitric oxide, hydroxyl and molecular oxygen as signatures of nitrogen, oxygen, and water rich atmospheres of terrestrial type exoplanets "highlighted" by the magnetic activity from young G and K main-sequence stars. The signals from these fundamental chemical prerequisites of life we call atmospheric "beacons of life" create a unique opportunity to perform direct imaging observations of Earth-sized exoplanets with high signal-to-noise and low spectral resolution with the upcoming NASA missions.

Description: As human habitation and eventual colonization of space becomes an inevitable reality, there is a necessity to understand how organisms develop over the life span in the space environment. Microgravity, altered CO2, radiation and psychological stress are some of the key factors that could affect mammalian reproduction and development in space, however there is a paucity of information on this topic. Here we combine early (neonatal) in vivo spectroscopic imaging with an adult emotionality assay following a common obstetric complication (prenatal asphyxia) likely to occur during gestation in space. The neural metabolome is sensitive to alteration by degenerative changes and developmental disorders, thus we hypothesized that that early neonatal neurometabolite profiles can predict adult response to novelty. Late gestation fetal rats were exposed to moderate asphyxia by occluding the blood supply feeding one of the rats pair uterine horns for 15min. Blood supply to the opposite horn was not occluded (within-litter cesarean control). Further comparisons were made with vaginal (natural) birth controls. In one-week old neonates, we measured neurometabolites in three brain areas (i.e., striatum, prefrontal cortex, and hippocampus). Adult perinatally-asphyxiated offspring exhibited greater anxiety-like behavioral phenotypes (as measured the composite neurobehavioral assay involving open field activity, responses to novel object, quantification of fecal droppings, and resident-intruder tests of social behavior). Further, early neurometabolite profiles predicted adult responses. Non-invasive MRS screening of mammalian offspring is likely to advance ground-based space analogue studies informing mammalian reproduction in space, and achieving high-priority.

Description: Spaceflight imposes multiple stresses on biological systems resulting in genome-scale adaptations. Understanding these adaptations and their underlying molecular mechanisms is important to clarifying and reducing the risks associated with spaceflight. One such risk is infection by microbes present in spacecraft and their associated systems and inhabitants. This risk is compounded by results suggesting that some microbes may exhibit increased virulence after exposure to spaceflight conditions. The yeast, S. cerevisiae, is a powerful microbial model system, and it's response to spaceflight has been studied for decades. However, to date, these studies have utilized common lab strains. Yet studies on trait variation in S. cerevisiae demonstrate that these lab strains are not representative of wild yeast and instead respond to environmental stimuli in an atypical manner. Thus, it is not clear how transferable these results are to the wild S. cerevisiae strains likely to be encountered during spaceflight. To determine if diverse S. cerevisiae strains exhibit a conserved response to simulated microgravity, we will utilize a collection of 100 S. cerevisiae strains isolated from clinical, environmental and industrial settings. We will place selected S. cerevisiae strains in simulated microgravity using a high-aspect rotating vessel (HARV) and document their transcriptional response by RNA-sequencing and quantify similarities and differences between strains. Our research will have a strong impact on the understanding of how genetic diversity of microorganisms effects their response to spaceflight, and will serve as a platform for further studies.

Description: The recent discoveries of pulsed X-ray emission from three ultraluminous X-ray (ULX) sources have finally enabled us to recognize a subclass within the ULX class: the great pretenders, neutron stars (NSs) that appear to emit X-ray radiation at isotropic luminosities Lx = 7 x 10(exp 39) erg/s - 1 x 10(exp 41) erg/s only because their emissions are strongly beamed toward our direction and our sight lines are offset by only a few degrees from their magnetic-dipole axes. The three known pretenders appear to be stronger emitters than the presumed black holes of the ULX class, such as Holmberg II & IX X-1, IC10 X-1 and NGC 300 X-1. For these three NSs, we have adopted a single reasonable assumption, that their brightest observed outbursts unfold at the Eddington rate, and we have calculated both their propeller states and their surface magnetic-field magnitudes. We find that the results are not at all different from those recently obtained for the Magellanic Be/X-ray pulsars: the three NSs reveal modest magnetic fields of about 0.3 - 0.4 TG and beamed propeller-line X-ray luminosities of approx. 10(exp 36) - 10(exp 37) erg/s, substantially below the Eddington limit.

Description: We present two state-of-the-art models of the solar system, one corresponding to the present day and one to the Archean Eon 3.5 billion years ago. Each model contains spatial and spectral information for the star, the planets, and the interplanetary dust, extending to 50 au from the Sun and covering the wavelength range 0.3-2.5 micron. In addition, we created a spectral image cube representative of the astronomical backgrounds that will be seen behind deep observations of extrasolar planetary systems, including galaxies and Milky Way stars. These models are intended as inputs to high-fidelity simulations of direct observations of exoplanetary systems using telescopes equipped with high-contrast capability. They will help improve the realism of observation and instrument parameters that are required inputs to statistical observatory yield calculations, as well as guide development of post-processing algorithms for telescopes capable of directly imaging Earth-like planets.

Description: Polarization measurements provide strong constraints on models for emission from rotation-powered pulsars. We present multiwavelength polarization predictions showing that measurements over a range of frequencies can be particularly important for constraining the emission location, radiation mechanisms, and system geometry. The results assume a generic model for emission from the outer magnetosphere and current sheet in which optical to hard X-ray emission is produced by synchrotron radiation (SR) from electron-positron pairs and gamma-ray emission is produced by curvature radiation (CR) or SR from accelerating primary electrons. The magnetic field structure of a force-free magnetosphere is assumed and the phase-resolved and phase-averaged polarization is calculated in the frame of an inertial observer. We find that large position angle (PA) swings and deep depolarization dips occur during the light-curve peaks in all energy bands. For synchrotron emission, the polarization characteristics are strongly dependent on photon emission radius with larger, nearly 180deg, PA swings for emission outside the light cylinder (LC) as the line of sight crosses the current sheet. The phase-averaged polarization degree for SR is less that 10% and around 20% for emission starting inside and outside the LC, respectively, while the polarization degree for CR is much larger, up to 40%-60%. Observing a sharp increase in polarization degree and a change in PA at the transition between X-ray and gamma-ray spectral components would indicate that CR is the gamma-ray emission mechanism.

Description: Electrochemical detection of biological molecules is a pertinent topic and application in many fields such as medicine, environmental spills, and life detection in space. Proteases, a class of molecules of interest in the search for life, catalyze the hydrolysis of peptides. Trypsin, a specific protease, was chosen to investigate an optimized enzyme detection system using electrochemistry. This study aims at providing the ideal functionalization of an electrode that can reliably detect a signal indicative of an enzymatic reaction from an Enceladus sample.

Description: Two transit survey missions will have been flown by NASA prior to the launch of ESA's PLATO Mission in 2026, laying the groundwork for exoplanet discovery via the transit method. The Kepler Mission, which launched in 2009, collected data on its 100+ square degree field of view for four years before failure of a reaction wheel ended its primary mission. The results from Kepler include 2300+ confirmed or validated exoplanets, 2200+ planetary candidates, 2100+ eclipsing binaries. Kepler also revolutionized the field of asteroseismology by measuring the pressure mode oscillations of over 15000 solar-like stars spanning the lifecycle of such stars from hydrogen-burning dwarfs to helium-burning red giants. The re-purposed Kepler Mission, dubbed K2, continues to observe fields of view in and near the ecliptic plane for 80 days each, significantly broadening the scope of the astrophysical investigations as well as discovering an additional 156 exoplanets to date. The TESS mission will launch in 2017 to conduct an all-sky survey for small exoplanets orbiting stars 10X closer and 100X brighter than Kepler exoplanet host stars, allowing for far greater follow-up and characterization of their masses as well as their sizes for at least 50 small planets. Future assets such as James Webb Space Telescope, and ground-based assets such as ESOs Very Large Telescope (VLT) array, the Exremely Large Telescope (ELT), and the Thirty Meter Telescope (TMT) will be able to characterize the atmospheric composition and properties of these small planets. TESS will observe each 24 X 96 field of view for 30 days and thereby cover first the southern and then the northern hemisphere over 13 pointings during each year of the primary mission. The pole-most camera will observe the James Webb continuous viewing zone for one year in each hemisphere, permitting much longer period planets to be detected in this region. The PLATO mission will seek to detect habitable Earth-like planets with an instrument composed of 26 small telescopes in several 2232 square deg FOVs with a range of observation durations over a mission lifetime of up to eight years. This paper summarizes the findings of the KeplerK2 missions, previews the likely results from the TESS mission, and explores the lessons learned and to be learned from these prior missions that can be incorporated into the observation and data reduction strategy for the PLATO Mission so as to maximize the science return.

Description: The Transiting Exoplanet Survey Satellite (TESS) science pipeline is being developed by the Science Processing Operations Center (SPOC) at NASA Ames Research Center based on the highly successful Kepler Mission science pipeline. Like the Kepler pipeline, the TESS science pipeline will provide calibrated pixels, simple and systematic error-corrected aperture photometry, and centroid locations for all 200,000+ target stars, observed over the 2-year mission, along with associated uncertainties. The pixel and light curve products are modeled on the Kepler archive products and will be archived to the Mikulski Archive for Space Telescopes (MAST). In addition to the nominal science data, the 30-minute Full Frame Images (FFIs) simultaneously collected by TESS will also be calibrated by the SPOC and archived at MAST. The TESS pipeline will search through all light curves for evidence of transits that occur when a planet crosses the disk of its host star. The Data Validation pipeline will generate a suite of diagnostic metrics for each transit-like signature discovered, and extract planetary parameters by fitting a limb-darkened transit model to each potential planetary signature. The results of the transit search will be modeled on the Kepler transit search products (tabulated numerical results, time series products, and pdf reports) all of which will be archived to MAST.

Description: Thermonuclear flashes of hydrogen and helium accreted onto neutron stars produce the frequently observed Type I X-ray bursts. It is the current paradigm that almost all material burns in a burst, after which it takes hours to accumulate fresh fuel for the next burst. In rare cases, however, bursts are observed with recurrence times as short as minutes. We present the first one-dimensional multi-zone simulations that reproduce this phenomenon. Bursts that ignite in a relatively hot neutron star envelope leave a substantial fraction of the fuel unburned at shallow depths. In the wake of the burst, convective mixing events driven by opacity bring this fuel down to the ignition depth on the observed timescale of minutes. There, unburned hydrogen mixes with the metal-rich ashes, igniting to produce a subsequent burst. We find burst pairs and triplets, similar to the observed instances. Our simulations reproduce the observed fraction of bursts with short waiting times of approximately 30%, and demonstrate that short recurrence time bursts are typically less bright and of shorter duration.

Description: Future space exploration and long duration space flight will pose an array of challenges to the health and wellbeing of astronauts. Since 2015, Fairchild Tropical Botanic Garden (FTBG), in partnership with NASA's Veggie team, has been testing edible crops for space flight potential through a series of citizen science experiments. FTBG's interest in classroom-based science projects, along with NASA's successful operation of the Veggie system aboard the International Space Station (ISS), led to a NASA-FTBG partnership that gave rise to the Growing Beyond Earth STEM Initiative (GBE). Established in 2015, GBE now involves 131 middle and high school classrooms in South Florida, all conducting simultaneous plant science experiments. The results of those experiments (both numeric and visual) are directly shared with the space food production researchers at KSC. Through this session, we will explore the successful classroom implementation and integration into the curriculum, how the data is being used and the impact of the project on participating researchers, teachers, and students. Participating schools were supplied with specialized LED-lit growth chambers, mimicking the Veggie system on ISS, for growing edible plants under similar physical and environmental constraints. Research protocols were provided by KSC scientists, while edible plant varieties were selected mainly by the botanists at FTBG. In a jointly-led professional development workshop, participating teachers were trained to conduct GBE experiments in their classrooms. Teachers were instructed to not only teach basic botany concepts, but to also demonstrate practical applications of math, physics and chemistry. As experiments were underway, students shared data on plant germination, growth, and health in an online spreadsheet. Results from the students research show a promising selection of new plant candidates for possible further testing. Over a two year period, more than 5000 South Florida students, ages 11 to 18, participated in GBE. Evaluation of the program shows an increased knowledge of and interest in science and science careers among students. The program has also boosted the demand for summer high school internships at FTBG, further developing expertise in plant research and science related to space exploration. Supported by a grant from NASA (NNX16AM32G) to Fairchild Tropical Botanic Garden.

Description: Review freeform optic applications as NASA. Describe design study results showing benefits of freeform optics to the instrument size, image quality, and field of view. Review areas of study and improvements needed to freeform manufacturing for future applications.

Description: No abstract available

Description: We present results from four new broadband X-ray observations of the extreme ultraluminous X-ray source Holmberg IX X-1 (L (sub X) greater than 10 (sup 40) ergs per second), performed by Suzaku and NuSTAR in coordination. Combined with the archival data, we now have broadband observations of this remarkable source from six separate epochs. Two of these new observations probe lower fluxes than seen previously, allowing us to extend our knowledge of the broadband spectral variability exhibited. The spectra are well fit by two thermal blackbody components that dominate the emission below 10 kiloelectronvolts, as well as a steep (Gamma approximately equal to 3.5) power-law tail thatdominates above approximately 15 kiloelectronvolts. Remarkably, while the 0.3-10.0 kiloelectronvolts flux varies by a factor of approximately 3 between all these epochs, the 15-40 kiloelectronvolts flux varies by only approximately 20 percent. Although the spectral variability is strongest in the approximately 1-10 kiloelectronvolts band, both of the thermal components are required to vary when all epochs are considered. We also revisit the search for iron absorption features by leveraging the high-energy NuSTAR data to improve our sensitivity to extreme velocity outflows in light of the ultra-fast outflow recently detected in NGC 1313 X-1. Iron absorption from a similar outflow along our line of sight can be ruled out in this case. We discuss these results in the context of super-Eddington accretion models that invoke a funnel-like geometry for the inner flow, and propose a scenario in which we have an almost face-on view of a funnel that expands to larger radii with increasing flux, resulting in an increasing degree of geometrical collimation for the emission from intermediate-temperature regions.

Description: Quantum electrodynamics in very strong Coulomb fields is one scope which has not yet been tested experimentally with sufficient accuracy to really determine whether the perturbative approach is valid. One sensitive test is the determination of the 1s Lamb shift in highly-charged very heavy ions. The 1s Lamb shift of hydrogen-like lead (Pb81+) and gold (Au78+) has been determined using the novel detector concept of silicon microcalorimeters for the detection of hard x-rays. The results of (260 +/- 53) eV for lead and (211 +/- 42) eV for gold are within the error bars in good agreement with theoretical predictions. To our knowledge, for hydrogen-like lead, this represents the most accurate determination of the 1s Lamb shift.

Description: Oxygen fugacity plays an important role in determining the detailed physical and chemical aspects of planets and their building blocks. Basic chemical properties such as the amount of oxidized Fe in a mantle (as FeO), the nature of alloying elements in the core (S, C, H, O, Si), and the solubility of various volatile elements in the silicate and metallic portions of embryos and planets can influence physical properties such as the size of the core, the liquidus and solidus of the mantle and core, and the speciation of volatile compounds contributing to atmospheres. This paper will provide an overview of the range of fO2 variation observed in primitive and differentiated materials that may have participated in accretion (cosmic dust, Star-dust and meteorites), a comparison to observations of planetary fO2 (Mercury, Mars and Earth), and a discus-sion of timing of variation of fO2 within both early and later accreted materials. This overview is meant to promote discussion and interaction between students of these two stages of planet formation to identify areas where more work is needed.

Description: During its first 18 years of operation, the cold (about -60degC) optical blocking filters of the Advanced CCD Imaging Spectrometer (ACIS), aboard the Chandra X-ray Observatory, has accumulated a growing layer of molecular contamination, which attenuates low-energy x rays. Over the past several years, the accumulation rate, spatial distribution, and composition have changed. This evolution has motivated further analysis of contamination migration within and near the ACIS cavity, in part to evaluate potential bake-out scenarios intended to reduce the level of contamination. This paper, the fourth on this topic, reports the results of recent contamination-migration simulations and their relevance to a decision whether to bake-out the ACIS instrument.

Description: We present highlights from a large set of simulations of a hot Jupiter atmosphere, nominally based on HD 209458b, aimed at exploring both the evolution of the deep atmosphere, and the acceleration of the zonal flow or jet. We find the occurrence of a super-rotating equatorial jet is robust to changes in various parameters, and over long timescales, even in the absence of strong inner or bottom boundary drag. This jet is diminished in one simulation only, where we strongly force the deep atmosphere equator-to-pole temperature gradient over long timescales. Finally, although the eddy momentum fluxes in our atmosphere show similarities with the proposed mechanism for accelerating jets on tidally-locked planets, the picture appears more complex. We present tentative evidence for a jet driven by a combination of eddy momentum transport and mean flow.

Description: A magnetic field dragged from the galactic disk, along with inflowing gas, can provide vertical support to the geometrically and optically thick pc (parsec) -scale torus in AGNs (Active Galactic Nuclei). Using the Soloviev solution initially developed for Tokamaks, we derive an analytical model for a rotating torus that is supported and confined by a magnetic field. We further perform three-dimensional magneto-hydrodynamic simulations of X-ray irradiated, pc-scale, magnetized tori. We follow the time evolution and compare models that adopt initial conditions derived from our analytic model with simulations in which the initial magnetic flux is entirely contained within the gas torus. Numerical simulations demonstrate that the initial conditions based on the analytic solution produce a longer-lived torus that produces obscuration that is generally consistent with observed constraints.

Description: X-ray observations of supernova remnants (SNRs) allow us to investigate the chemical inhomogeneity of ejecta, offering unique insight into the nucleosynthesis in supernova explosions. Here we present detailed imaging and spectroscopic studies of the Fe knot located along the eastern rim of the Type Ia SNR Tycho ( SN 1572) using Suzaku and Chandra long-exposure data. Surprisingly, the Suzaku spectrum of this knot shows no emission from Cr, Mn, or Ni, which is unusual for the Fe-rich regions in this SNR. Within the framework of the canonical delayed-detonation models for SN Ia, the observed mass ratios M(sub Cr)/M(sub Fe) is less than 0.023, M(sub Mn)/M(sub Fe) is less than 0.012, and M(sub Ni)/M(sub Fe) is less than 0.029 (at 90% confidence) can only be achieved for a peak temperature of (5.3 - 5.7) x 10(exp. 9) K and a neutron excess of approximately less than 2.0 x 10(exp. -3). These constraints rule out the deep, dense core of a Chandrasekhar-mass white dwarf as the origin of the Fe knot and favor either incomplete Si burning or an Alpha-rich freeze-out regime, probably close to the boundary. An explosive He burning regime is a possible alternative, although this hypothesis is in conflict with the main properties of this SNR.

Description: We analyze dispersion measure(DM) variations of 37 millisecond pulsars in the nine-year North American Nanohertz Observatory for Gravitational Waves (NANOGrav) data release and constrain the sources of these variations. DM variations can result from a changing distance between Earth and the pulsar, inhomogeneities in the interstellar medium, and solar effects. Variations are significant for nearly all pulsars, with characteristic timescales comparable to or even shorter than the average spacing between observations. Five pulsars have periodic annual variations, 14 pulsars have monotonically increasing or decreasing trends, and 14 pulsars show both effects. Of the four pulsars with linear trends that have line-of-sight velocity measurements, three are consistent with a changing distance and require an overdensity of free electrons local to the pulsar. Several pulsars show correlations between DM excesses and lines of sight that pass close to the Sun. Mapping of the DM variations as a function of the pulsar trajectory can identify localized interstellar medium features and, in one case, an upper limit to the size of the dispersing region of 4 au. Four pulsars show roughly Kolmogorov structure functions (SFs), and another four show SFs less steep than Kolmogorov. One pulsar has too large an uncertainty to allow comparisons. We discuss explanations for apparent departures from a Kolmogorov-like spectrum, and we show that the presence of other trends and localized features or gradients in the interstellar medium is the most likely cause.

Description: The stellar initial mass function (IMF), which is often assumed to be universal across unresolved stellar populations, has recently been suggested to be bottom-heavy for massive ellipticals. In these galaxies, the prevalence of gravity-sensitive absorption lines (e.g., Na I and Ca II) in their near-IR spectra implies an excess of low-mass (m 〈 or approx. = 0.5 Stellar Mass) stars over that expected from a canonical IMF observed in low-mass ellipticals. A direct extrapolation of such a bottom-heavy IMF to high stellar masses (m 〉 or approx. = 8 Stellar Mass) would lead to a corresponding deficit of neutron stars and black holes, and therefore of low-mass X-ray binaries (LMXBs), per unit near-IR luminosity in these galaxies. Peacock et al. searched for evidence of this trend and found that the observed number of LMXBs per unit K-band luminosity (N/LK) was nearly constant. We extend this work using new and archival Chandra X-ray Observatory and Hubble Space Telescope observations of seven low-mass ellipticals where N/LK is expected to be the largest and compare these data with a variety of IMF models to test which are consistent with the observed N/LK. We reproduce the result of Peacock et al., strengthening the constraint that the slope of the IMF at m 〉 or approx. = 8 Stellar Mass must be consistent with a Kroupa-like IMF. We construct an IMF model that is a linear combination of a Milky Way-like IMF and a broken power-law IMF, with a steep slope (alpha1 = 3.84) for stars 〈 0.5 Stellar Mass (as suggested by near-IR indices), and that flattens out (alpha2 = 2.14) for stars 〉 0.5 Stellar Mass, and discuss its wider ramifications and limitations.

Description: No abstract available

Description: The Kepler era of exoplanetary discovery has presented the Astronomical community with a cornucopia of planetary systems very different from the one which we inhabit. It has long been known that Jupiter plays a major role in the orbital parameters of Mars and its climate, but there is also a long-standing belief that Jupiter would play a similar role for Earth if not for its large moon. Using a three dimensional general circulation model (3-D GCM) with a fully-coupled ocean we simulate what would happen to the climate of an Earth-like world if Mars did not exist, but a Jupiter-like planet was much closer to Earths orbit. We investigate two scenarios that involve evolution of the Earth-like planets orbital eccentricity from 0 to 0.066 on a time scale of 4500 years, and from 0 to 0.283 over 6500 years. We discover that during most of the 6500 year scenario the planet would experience a moist greenhouse effect when near periastron. This could have implications for the ability of such a world to retain an ocean on time scales of 109 years. More Earth-like planets in multi-planet systems will be discovered as we continue to survey the skies and the results herein show that the proximity of large gas giant planets may play an important role in the habitabilty of these worlds. These are the first such 3-D GCM simulations using a fully-coupled ocean with a planetary orbit that evolves over time due to the presence of a giant planet.

Description: No abstract available

Description: This design study was conducted to support the HABEX project. There are a number of companion papers at this conference which go into detail on what all the HABEX goals are. The objective of this paper is to establish a baseline primary mirror design which satisfies the following structural related requirements. The designs in this study have a high TRL (Technology Readiness Level), realistic manufacturing limits and performance in line with the HABEX mission. A secondary goal of the study was to evaluate a number competing criteria for the selection. Questions such as differences in the on axis versus off axis static and dynamic response to disturbances. This study concentrates on the structural behavior, companion papers cover thermal and long term stability aspects of the problem.

Description: The Advanced Mirror Technology Development (AMTD) project is in Phase 2 of a multiyear effort initiated in Fiscal Year (FY) 2012, to mature the Technology Readiness Level (TRL) of critical technologies required to enable 4-m-or-larger monolithic or segmented ultraviolet, optical, and infrared (UVOIR) space telescope primary-mirror assemblies for general astrophysics, ultra-high-contrast observations of exoplanets, and National Interest missions. Key accomplishments of 2016/17 include the completion of the Harris Corp approximately 150 Hz 1.5-meter Ultra-Low Expansion (ULE Registered trademark) mirror substrate using stacked core method to demonstrate lateral stability of the stacked core technology, as well as the characterization and validation by test of the mechanical and thermal performance of the 1.2-meter Zerodur (Registered trademark) mirror using the STOP model prediction and verification of CTE homogeneity.

Description: Polycyclic aromatic hydrocarbons (PAHs) are believed to be ubiquitous in space therefore represent an important class of molecules for the field of astrochemistry. PAHs are relatively stable under interstellar conditions, account for a significant fraction of the known Universe's molecular carbon inventory, and are believed responsible for numerous telltale interstellar infrared emission bands. PAHs can be subdivided into numerous classes, one of which is Hydrogenated PAHs (Hn-PAHs). Hn-PAHs are multi-ringed partially aromatic compounds with excess hydrogenation, leading to a partial disruption of the aromatic system. The infrared spectra of these compounds produce telltale signatures that make them distinct from ordinary aromatic or aliphatic molecules (or a mixture of both). Hn-PAHs may be an important subclass of PAHs that could explain the spectra of some astronomical objects with anomalously large 3.4 micron features. The 3.4 micron feature observed in these objects may be associated with the aliphatic C-H stretching vibrations of the excess hydrogen. If this presumption is correct, we also expect to observe methylene scissoring modes at 6.9 microns. We have recently conducted a series of follow-up observations to compliment our laboratory experiments into the properties of Hn-PAHs. Here we present our laboratory and observational results in support of the hypothesis that Hn-PAHs are a viable candidate molecule as the emission source for numerous post-asymptotic giant branch objects with abnormally large 3.4 micron features.

Description: NASA invests in professional coaching as a way to accelerate the development of its staff. The speaker shares one foundational human development model in coaching - the Six Streams - and applies it to the challenges that new scientists face. The speaker also describes how a new scientist can develop greater capabilities in the Six Streams so that they can become a more effective scientist and feel more satisfaction with their work.

Description: We hypothesize that DNA damage induced by high local energy deposition, occurring when cells are traversed by high-LET (Linear Energy Transfer) particles, can be experimentally modeled by exposing cells to high doses of low-LET. In this work, we validate such hypothesis by characterizing and correlating the time dependence of 53BP1 radiation-induced foci (RIF) for various doses and LET across 72 primary skin fibroblast from mice. This genetically diverse population allows us to understand how genetic may modulate the dose and LET relationship. The cohort was made on average from 3 males and 3 females belonging to 15 different strains of mice with various genetic backgrounds, including the collaborative cross (CC) genetic model (10 strains) and 5 reference mice strains. Cells were exposed to two fluences of three HZE (High Atomic Energy) particles (Si 350 megaelectronvolts per nucleon, Ar 350 megaelectronvolts per nucleon and Fe 600 megaelectronvolts per nucleon) and to 0.1, 1 and 4 grays from a 160 kilovolt X-ray. Individual radiation sensitivity was investigated by high throughput measurements of DNA repair kinetics for different doses of each radiation type. The 53BP1 RIF dose response to high-LET particles showed a linear dependency that matched the expected number of tracks per cell, clearly illustrating the fact that close-by DNA double strand breaks along tracks cluster within one single RIF. By comparing the slope of the high-LET dose curve to the expected number of tracks per cell we computed the number of remaining unrepaired tracks as a function of time post-irradiation. Results show that the percentage of unrepaired track over a 48 hours follow-up is higher as the LET increases across all strains. We also observe a strong correlation between the high dose repair kinetics following exposure to 160 kilovolts X-ray and the repair kinetics of high-LET tracks, with higher correlation with higher LET. At the in-vivo level for the 10-CC strains, we observe that drops in the number of T-cells and B-cells found in the blood of mice 24 hours after exposure to 0.1 gray of 320 kilovolts X-ray correlate well with slower DNA repair kinetics in skin cells exposed to X-ray. Overall, our results suggest that repair kinetics found in skin is a surrogate marker for in-vivo radiation sensitivity in other tissue, such as blood cells, and that such response is modulated by genetic variability.

Description: The Origins Space Telescope (OST) is the mission concept for the Far Infrared Surveyor, a study in development by NASA in preparation for the 2020 Astronomy and Astrophysics Decadal Survey. The science program that has been selected to drive the OST performance requirements is broad, covering four main themes: Charting the Rise of Metals, Dust, and the First Galaxies; Unveiling the Growth of Black Holes and Galaxies Over Cosmic Time; Tracing the Signatures of Life and the Ingredients of Habitable Worlds; and Characterizing Small Bodies in the Solar System. The OST telescope itself will have a primary mirror diameter of 8-15 m (depending on the launch vehicle that is selected), will be diffraction-limited at 40m, and will be actively cooled to approximately 5K. Five science instruments have been base-lined for the observatory: a heterodyne instrument covering 150-500 m with a spectral resolving power of R1e7; a low-spectral resolution (R500) spectrometer covering 35-500 m; a high-spectral resolution (R1e5) spectrometer covering 50-500 m; a far-infrared imager (R15) covering 35-500m; and a mid-infrared imagerspectrometer (R15-500) covering 6-40m. In addition to having a vastly higher sensitivity than the corresponding SOFIA instrumentation that will allow more detailed follow-up of SOFIAs discoveries, the OST mission will be configured to provide efficient large-area mapping, which will further complement SOFIAs science capabilities by providing new targets for study by SOFIA. Furthermore, new SOFIA instruments can provide an excellent testbed for the advanced far-infrared detector technologies what will be required to achieve the anticipated OST performance.

Description: We present a robust method to characterize the gravitational wave emission from the remnant of a neutron star coalescence. Our approach makes only minimal assumptions about the morphology of the signal and provides a full posterior probability distribution of the underlying waveform. We apply our method on simulated data from a network of advanced ground-based detectors and demonstrate the gravitational wave signal reconstruction. We study the reconstruction quality for different binary configurations and equations of state for the colliding neutron stars. We show how our method can be used to constrain the yet-uncertain equation of state of neutron star matter. The constraints on the equation of state we derive are complimentary to measurements of the tidal deformation of the colliding neutron stars during the late inspiral phase. In the case of a nondetection of a post-merger signal following a binary neutron star inspiral we show that we can place upper limits on the energy emitted.

Description: Context. X-ray spectra of accreting pulsars are generally observed to vary with their X-ray luminosity. In particular, the hardness of the X-ray continuum is found to depend on luminosity. In a few sources, the correlation between the energy of the cyclotron resonance scattering feature (CRSF) and the luminosity is clear. Different types (signs) of the correlation are believed to reflect different accretion modes. Aims. We analyse two NuSTAR observations of the transient accreting pulsar Cep X-4 during its 2014 outburst. Our analysis is focused on a detailed investigation of the dependence of the CRSF energy and of the spectral hardness on X-ray luminosity, especially on short timescales. Methods. To investigate the spectral changes as a function of luminosity within each of the two observations, we used the intrinsic variability of the source on the timescale of individual pulse cycles (tens of seconds), the so-called pulse-to-pulse variability. Results. We find that the NuSTAR spectrum of Cep X-4 contains two CRSFs: the fundamental line at ~30 keV and its harmonic at ~55 keV. We find for the first time that the energy of the fundamental CRSF increases and the continuum becomes harder with increasing X-ray luminosity not only between the two observations, that is, on the long timescale, but also within an individual observation, on the timescale of a few tens of seconds. We investigate these dependencies in detail including their non-linearity. We discuss a possible physical interpretation of the observed behaviour in the frame of a simple one-dimensional model of the polar emitting region with a collisionless shock formed in the infalling plasma near the neutron star surface. With this model, we are able to reproduce the observed variations of the continuum hardness ratio and of the CRSF energy with luminosity.

Description: We report the identification of a bright hard X-ray source dominating the M31 bulge above 25 keV from a simultaneous NuSTAR-Swift observation. We find that this source is the counterpart to Swift J0042.6+4112, which was previously detected in the Swift BAT All-sky Hard X-ray Survey. This Swift BAT source had been suggested to be the combined emission from a number of point sources; our new observations have identified a single X-ray source from 0.5 to 50 keV as the counterpart for the first time. In the 0.5-10 keV band, the source had been classified as an X-ray Binary candidate in various Chandra and XMM-Newton studies; however, since it was not clearly associated with Swift J0042.6+4112, the previous E〈10 keV observations did not generate much attention. This source has a spectrum with a soft X-ray excess (kT 0.2 keV) plus a hard spectrum with a power law of G ~ 1 and a cutoff around 15-20 keV, typical of the spectral characteristics of accreting pulsars. Unfortunately, any potential pulsation was undetected in the NuSTAR data, possibly due to insufficient photon statistics. The existing deep HST images exclude high-mass (〉3 solar mass) donors at the location of this source. The best interpretation for the nature of this source is an X-ray pulsar with an intermediate-mass (〈3 solar mass) companion or a symbiotic X-ray binary. We discuss other possibilities in more detail.

Description: Context. Cyclotron resonant scattering features (CRSFs) are formed by scattering of X-ray photons o_ quantized plasma electrons in the strong magnetic field (of the order 1012 G) close to the surface of an accreting X-ray pulsar. Due to the complex scattering cross-sections, the line profiles of CRSFs cannot be described by an analytic expression. Numerical methods, such as Monte Carlo (MC) simulations of the scattering processes, are required in order to predict precise line shapes for a given physical setup, which can be compared to observations to gain information about the underlying physics in these systems.Aims. A versatile simulation code is needed for the generation of synthetic cyclotron lines. Sophisticated geometries should be investigatable by making their simulation possible for the first time.Methods. The simulation utilizes the mean free path tables described in the first paper of this series for the fast interpolation of propagation lengths. The code is parallelized to make the very time-consuming simulations possible on convenient time scales. Furthermore, it can generate responses to monoenergetic photon injections, producing Green's functions, which can be used later to generate spectra for arbitrary continua.Results. We develop a new simulation code to generate synthetic cyclotron lines for complex scenarios, allowing for unprecedented physical interpretation of the observed data. An associated XSPEC model implementation is used to fit synthetic line profiles to NuSTAR data of Cep X-4. The code has been developed with the main goal of overcoming previous geometrical constraints in MC simulations of CRSFs. By applying this code also to more simple, classic geometries used in previous works, we furthermore address issues of code verification and cross-comparison of various models. The XSPEC model and the Green's function tables are available online (see link in footnote, page 1).

Description: "This work presents updates to the coronagraph and telescope components of the Segmented Aperture Interfer-ometric Nulling Testbed (SAINT). The project pairs an actively-controlled macro-scale segmented mirror withthe Visible Nulling Coronagraph (VNC) towards demonstrating capabilities for the future space observatoriesneeded to directly detect and characterize a significant sample of Earth-sized worlds around nearby stars inthe quest for identifying those which may be habitable and possibly harbor life. Efforts to improve the VNCwavefront control optics and mechanisms towards repeating narrowband results are described. A narrative isprovided for the design of new optical components aimed at enabling broadband performance. Initial work withthe hardware and software interface for controlling the segmented telescope mirror is also presented."

Description: The Be X-ray binary EXO2030+375 was in an extended low-luminosity state during most of 2016. We observed this state with NuSTAR and Swift, supported by INTEGRAL observations and optical spectroscopy with the Nordic Optical Telescope (NOT). We present a comprehensive spectral and timing analysis of these data here to study the accretion geometry and investigate a possible onset of the propeller e ect. The H data show that the circumstellar disk of the Be-star is still present. We measure equivalent widths similar to values found during more active phases in the past, indicating that the low-luminosity state is not simply triggered by a smaller Be disk. The NuSTAR data, taken at a 3-78 keV luminosity of 6:8 1035 erg s-1 (for a distance of 7.1 kpc), are nicely described by standard accreting pulsar models such as an absorbed power law with a high-energy cuto. We find that pulsations are still clearly visible at these luminosities, indicating that accretion is continuing despite the very low mass transfer rate. In phaseresolved spectroscopy we find a peculiar variation of the photon index from 1.5 to 2.5 over only about 3% of the rotational period. This variation is similar to that observed with XMM-Newton at much higher luminosities. It may be connected to the accretion column passing through our line of sight. With Swift/XRT we observe luminosities as low as 1034 erg s-1 where the data quality did not allow us to search for pulsations, but the spectrum is much softer and well described by either a blackbody or soft power-law continuum. This softer spectrum might be due to the accretion being stopped by the propeller e ect and we only observe the neutron star surface cooling.

Description: In 2016 September, the microquasar Cygnus X-3 underwent a giant radio flare, which was monitored for 6 d with the Medicina Radio Astronomical Station and the Sardinia Radio Telescope. Long observations were performed in order to follow the evolution of the flare on an hourly scale, covering six frequency ranges from 1.5 to 25.6 GHz. The radio emission reached a maximum of 13.2 +/- 0.7 Jy at 7.2 GHz and 10 +/- 1 Jy at 18.6 GHz. Rapid flux variations were observed at high radio frequencies at the peak of the flare, together with rapid evolution of the spectral index: steepened from 0.3 to 0.6 (with S ) within 5 h. This is the first time that such fast variations are observed, giving support to the evolution from optically thick to optically thin plasmons in expansion moving outward from the core. Based on the Italian network (Noto, Medicina and SRT) and extended to the European antennas (Torun, Yebes, Onsala), very long baseline interferometry (VLBI) observations were triggered at 22 GHz on five different occasions, four times prior to the giant flare, and once during its decay phase. Flux variations of 2 h duration were recorded during the first session. They correspond to a mini-flare that occurred close to the core 10 d before the onset of the giant flare. From the latest VLBI observation we infer that 4 d after the flare peak the jet emission was extended over 30 mas.

Description: IGR J18214-1318, a Galactic source discovered by the International Gamma-Ray Astrophysics Laboratory, is a high-mass X-ray binary (HMXB) with a supergiant O-type stellar donor. We report on the XMM-Newton and NuSTAR observations that were undertaken to determine the nature of the compact object in this system. This source exhibits high levels of aperiodic variability, but no periodic pulsations are detected with a 90% confidence upper limit of 2% fractional rms between 0.00003-88 Hz, a frequency range that includes the typical pulse periods of neutron stars (NSs) in HMXBs (0.1-103 s). Although the lack of pulsations prevents us from definitively identifying the compact object in IGR J18214-1318, the presence of an exponential cutoff with e-folding energy 〈 30 keV in its 0.3-79 keV spectrum strongly suggests that the compact object is an NS. The X-ray spectrum also shows a Fe K emission line and a soft excess, which can be accounted for by either a partial-covering absorber with NH approximately equals 10(exp23)cm(exp2), which could be due to the inhomogeneous supergiant wind, or a blackbody component with = - kT 1.74+0.05 0.04 keV and R 〉〉 0.3 BB km, which may originate from NS hot spots. Although neither explanation for the soft excess can be excluded, the former is more consistent with the properties observed in other supergiant HMXBs. We compare IGR J18214-1318 to other HMXBs that lack pulsations or have long pulsation periods beyond the range covered by our observations.

Description: We present a comprehensive spectral analysis of the BeXRB GRO J1008-57 over a luminosity range of three orders of magnitude using NuSTAR, Suzaku, and RXTE data. We find significant evolution of the spectral parameters with luminosity. In particular, the photon index hardens with increasing luminosity at intermediate luminosities in the range 10(sup 36) to 10 (sup 37) ergs per second. This evolution is stable and repeatedly observed over different outbursts. However, at the extreme ends of the observed luminosity range, we find that the correlation breaks down, with a significance level of at least 3:7sigma. We conclude that these changes indicate transitions to different accretion regimes, which are characterized by different deceleration processes, such as Coulomb or radiation breaking. We compare our observed luminosity levels of these transitions to theoretical predications and discuss the variation of those theoretical luminosity values with fundamental neutron star parameters. Finally, we present detailed spectroscopy of the unique "triple peaked" outburst in 2014/15 which does not fit in the general parameter evolution with luminosity. The pulse profile on the other hand is consistent with what is expected at this luminosity level, arguing against a change in accretion geometry. In summary, GRO J1008-57 is an ideal target to study different accretion regimes due to the well-constrained evolution of its broad-band spectral continuum over several orders of magnitude in luminosity.

Description: Bright and eclipsing, the high-mass X-ray binary Vela X-1 offers a unique opportunity to study accretion onto a neutron star from clumpy winds of O/B stars and to disentangle the complex accretion geometry of these systems. In Chandra-HETGS spectroscopy at orbital phase approximately 0.25, when our line of sight towards the source does not pass through the large-scale accretion structure such as the accretion wake, we observe changes in overall spectral shape on timescales of a few kiloseconds. This spectral variability is, at least in part, caused by changes in overall absorption and we show that such strongly variable absorption cannot be caused by unperturbed clumpy winds of O/B stars. We detect line features from high and low ionization species of silicon, magnesium, and neon whose strengths and presence depend on the overall level of absorption. These features imply a co-existence of cool and hot gas phases in the system, which we interpret as a highly variable, structured accretion flow close to the compact object such as has been recently seen in simulations of wind accretion in high-mass X-ray binaries.

Description: We report on two NuSTAR observations of the high-mass X-ray binary A 0535+26 taken toward the end of its normal 2015 outburst at very low 3-50 keV luminosities of approximately 1.4 times x 10 (sup 36) ergs per second and approximately 5 times x 10 (sup 35) ergs per second, which are complemented by nine Swift observations. The data clearly confirm indications seen in earlier data that the source's spectral shape softens as it becomes fainter. The smooth exponential rollover at high energies seen in the first observation evolves to a much more abrupt steepening of the spectrum at 20-30 keV. The continuum evolution can be nicely described with emission from a magnetized accretion column, modeled using the compmag model modified by an additional Gaussian emission component for the fainter observation. Between the two observations, the optical depth changes from 0.75 plus or minus 0.04 to 0.56 plus 0.01 (sup) minus 0.04 (sub), the electron temperature remains constant, and there is an indication that the column decreases in radius. Since the energy-resolved pulse profiles remain virtually unchanged in shape between the two observations, the emission properties of the accretion column reflect the same accretion regime. This conclusion is also confirmed by our result that the energy of the cyclotron resonant scattering feature (CRSF) at approximately 45 keV is independent of the luminosity, implying that the magnetic field in the region in which the observed radiation is produced is the same in both observations. Finally, we also constrain the evolution of the continuum parameters with the rotational phase of the neutron star. The width of the CRSF could only be constrained for the brighter observation. Based on Monte Carlo simulations of CRSF formation in single accretion columns, its pulse phase dependence supports a simplified fan beam emission pattern. The evolution of the CRSF width is very similar to that of the CRSF depth, which is, however, in disagreement with expectations.

Description: We report on the RXTE detection of a sudden increase in the absorption column density, NH, during the 2011 May outburst of GX 3041. The NH increased up to 16 10(exp 22) atoms cm(exp 2), which is a factor of 34 larger than what is usually measured during the outbursts of GX 3041 as covered by RXTE. Additionally, an increase in the variability of the hardness ratio as calculated from the energy resolved RXTE-Proportional Counter Array light curves is measured during this time range. We interpret these facts as an occultation event of the neutron star by material in the line of sight. Using a simple 3D model of an inclined and precessing Be disc around the Be-type companion, we are able to qualitatively explain the NH evolution over time. We are able to constrain the Be disc density to be of the order of 10(exp 11)g cm(exp 3). Our model strengthens the idea of inclined Be discs as origin of double-peaked outbursts as the derived geometry allows accretion twice per orbit under certain conditions.

Description: We present an investigation of clumpy galaxies in the Hubble Ultra Deep Field at 0.5 equal to or less than z equal to or less than 1.5 in the rest-frame far-ultraviolet (FUV) using Hubble Space Telescope Wide Field Camera 3 broadband imaging in F225W, F275W, and F336W. An analysis of 1404 galaxies yields 209 galaxies that host 403 kpc scale clumps. These host galaxies appear to be typical star-forming galaxies, with an average of 2 clumps per galaxy and reaching a maximum of 8 clumps. We measure the photometry of the clumps and determine the mass, age, and star formation rates (SFR) using the spectral energy distribution fitting code FAST (Fitting and Assessment of Synthetic Templates). We find that clumps make an average contribution of 19% to the total rest-frame FUV flux of their host galaxy. Individually, clumps contribute a median of 5% to the host galaxy SFR and an average of approximately 4% to the host galaxy mass, with total clump contributions to the host galaxy stellar mass ranging widely from lower than 1% up to 93%. Clumps in the outskirts of galaxies are typically younger, with higher SFRs, than clumps in the inner regions. The results are consistent with clump migration theories in which clumps form through violent gravitational instabilities in gas-rich turbulent disks, eventually migrate toward the center of the galaxies, and coalesce into the bulge.

Description: Exploration of the solar system is constrained by the cost of moving mass off Earth. Producing materials in situ will reduce the mass that must be delivered from earth. CO2 is abundant on Mars and manned spacecraft. On the ISS, NASA reacts excess CO2 with H2 to generate CH4 and H2O using the Sabatier System. The resulting water is recovered into the ISS, but the methane is vented to space. Thus, there is a capability need for systems that convert methane into valuable materials. Methanotrophic bacteria consume methane but these are poor synthetic biology platforms. Thus, there is a knowledge gap in utilizing methane in a robust and flexible synthetic biology platform. The yeast Pichia pastoris is a refined microbial factory that is used widely by industry because it efficiently secretes products. Pichia could produce a variety of useful products in space. Pichia does not consume methane but robustly consumes methanol, which is one enzymatic step removed from methane. Our goal is to engineer Pichia to consume methane thereby creating a powerful methane-consuming microbial factory.

Description: We present late-time observations by Swift and XMM-Newton of the tidal disruption event (TDE) ASASSN-15oi that reveal that the source brightened in the X-rays by a factor of approximately 10 one year after its discovery, while it faded in the UV (Ultra Violet)/optical by a factor of approximately 100. The XMM-Newton observations measure a soft X-ray blackbody component with kT(sub bb) (blackbody kiloteslas) approximating 45 electronvolts, corresponding to radiation from several gravitational radii of a central approximately 10 (sup 6) solar mass black hole. The last Swift epoch taken almost 600 days after discovery shows that the X-ray source has faded back to its levels during the UV/optical peak. The timescale of the X-ray brightening suggests that the X-ray emission could be coming from delayed accretion through a newly forming debris disk and that the prompt UV/optical emission is from the prior circularization of the disk through stream-stream collisions. The lack of spectral evolution during the X-ray brightening disfavors ionization breakout of a TDE "veiled" by obscuring material. This is the first time a TDE has been shown to have a delayed peak in soft X-rays relative to the UV/optical peak, which may be the first clear signature of the real-time assembly of a nascent accretion disk, and provides strong evidence for the origin of the UV/optical emission from circularization, as opposed to reprocessed emission of accretion radiation.

Description: BioSentinel is one of 13 secondary payloads to be deployed on Exploration Mission 1 (EM-1) in 2019. We will use the budding yeast Saccharomyces cerevisiae as a biosensor to determine how deep-space radiation affects living organisms and to potentially quantify radiation levels through radiation damage analysis. Radiation can damage DNA through double strand breaks (DSBs), which can normally be repaired by homologous recombination. Two yeast strains will be air-dried and stored in microfluidic cards within the payload: a wild-type control strain and a radiation sensitive rad51 mutant that is deficient in DSB repairs. Throughout the mission, the microfluidic cards will be rehydrated with growth medium and an indicator dye. Growth rates of each strain will be measured through LED detection of the reduction of the indicator dye, which correlates with DNA repair and the amount of radiation damage accumulated. Results from BioSentinel will be compared to analog experiments on the ISS and on Earth. It is well known that desiccation can damage yeast cells and decrease viability over time. We performed a screen for desiccation-tolerant rad51 strains. We selected 20 re-isolates of rad51 and ran a weekly screen for desiccation-tolerant mutants for five weeks. Our data shows that viability decreases over time, confirming previous research findings. Isolates L2, L5 and L14 indicate desiccation tolerance and are candidates for whole-genome sequencing. More time is needed to determine whether a specific strain is truly desiccation tolerant. Furthermore, we conducted an intracellular trehalose assay to test how intracellular trehalose concentrations affect or protect the mutant strains against desiccation stress. S. cerevisiae cell and reagent concentrations from a previously established intracellular trehalose protocol did not yield significant absorbance measurements, so we tested varying cell and reagent concentrations and determined proper concentrations for successful protocol use.

Description: Pre-flight groundbased testing done to prepare for the first Rodent Research mission validation flight, RR1 (Choi et al, 2016 PlosOne). We purified RNA and measured RIN values to assess quality of the samples. For protein, we measured liver enzyme activities. We tested protocol and methods of preservation to date. Here we present an overview of results related to tissue preservation from the RR1 validation mission and a summary of findings to date from investigators who received RR1 teissues various Biospecimen Sharing Program.

Description: GRB 120323A is a very intense short gamma-ray burst (GRB) detected simultaneously during its prompt gamma-ray emission phase with the Gamma-Ray Burst Monitor (GBM) on board the Fermi Gamma-Ray Space Telescope and the Konus experiment on board the Wind satellite. GBM and Konus operate in the kiloelectronvolt - megaelectronvolt regime; however, the GBM range is broader toward both the low and the high parts of the gamma-ray spectrum. Analyses of such bright events provide a unique opportunity to check the consistency of the data analysis as well as cross-calibrate the two instruments. We performed time-integrated and coarse time-resolved spectral analysis of GRB 120323A prompt emission. We conclude that the analyses of GBM and Konus data are only consistent when using a double-hump spectral shape for both data sets; in contrast, the single hump of the empirical Band function, traditionally used to fit GRB prompt emission spectra, leads to significant discrepancies between GBM and Konus analysis results. Our two-hump model is a combination of a thermal-like and a non-thermal component. We interpret the first component as a natural manifestation of the jet photospheric emission.

Description: Spaceflight imposes multiple stresses on biological systems resulting in genome-scale adaptations. Understanding these adaptations and their underlying molecular mechanisms is important to clarifying and reducing the risks associated with spaceflight. One such risk is infection by microbes present in spacecraft and their associated systems and inhabitants. This risk is compounded by results suggesting that some microbes may exhibit increased virulence after exposure to spaceflight conditions. The yeast, S. cerevisiae, is a powerful microbial model system, and its response to spaceflight has been studied for decades. However, to date, these studies have utilized common lab strains. Yet studies on trait variation in S. cerevisiae demonstrate that these lab strains are not representative of wild yeast and instead respond to environmental stimuli in an atypical manner. Thus, it is not clear how transferable these results are to the wild S. cerevisiae strains likely to be encountered during spaceflight. To determine if diverse S. cerevisiae strains exhibit a conserved response to simulated microgravity, we will utilize a collection of 100 S. cerevisiae strains isolated from clinical, environmental and industrial settings. We will place selected S. cerevisiae strains in simulated microgravity using a high-aspect rotating vessel (HARV) and document their transcriptional response by RNA-sequencing and quantify similarities and differences between strains. Our research will have a strong impact on the understanding of how genetic diversity of microorganisms effects their response to spaceflight, and will serve as a platform for further studies.

Description: We present unique NUV observations of a well-observed X-class flare from NOAA 12087 obtained at the Ondrejov Observatory. The flare shows a strong white-light continuum but no detectable emission in the higher Balmer and Lyman lines. Reuven Ramaty High-Energy Solar Spectroscopic Imager and Fermi observations indicate an extremely hard X-ray spectrum and gamma-ray emission. We use the RADYN radiative hydrodynamic code to perform two types of simulations: one where an energy of 3 x 10(exp 11) erg/sq cm/s is deposited by an electron beam with a spectral index of approx. = 3, and a second where the same energy is applied directly to the photosphere. The combination of observations and simulations allows us to conclude that the white-light emission and the suppression or complete lack of hydrogen emission lines is best explained by a model where the dominant energy deposition layer is located in the lower layers of the solar atmosphere, rather than the chromosphere.

Description: The influence of plasma environment on the atomic parameters associated with the K-vacancy states has been investigated theoretically for several iron ions. To do this, a time-averaged Debye-Huckel potential for both the electron-nucleus and electron-electron interactions has been considered in the framework of relativistic multiconfiguration Dirac-Fock computations. More particularly, the plasma screening effects on ionization potentials, K-thresholds, transition energies, and radiative rates have been estimated in the astrophysical context of accretion disks around black holes. In the present paper, we describe the behavior of those atomic parameters for Ne-, Na-, Ar-, and K-like iron ions.

Description: A search for the progenitor of SN 2010jl, an unusually luminous core-collapse supernova of Type IIn, using pre-explosion Hubble/WFPC2 and Spitzer/IRAC images of the region, yielded upper limits on the UV and near infrared (IR) fluxes from any candidate star. These upper limits constrain the luminosity and effective temperature of the progenitor, the mass of any pre-existing dust in its surrounding circumstellar medium (CSM), and dust proximity to the star. A lower limit on the CSM dust mass is required to hide a luminous progenitor from detection by Hubble. Upper limits on the CSM dust mass and constraints on its proximity to the star are set by requiring that the absorbed and reradiated IR emission not exceed the IRAC upper limits. Using the combined extinction-IR emission constraints, we present viable M(sub d)-R(sub 1) combinations, where M(sub d) and R(sub 1) are the CSM dust mass and its inner radius. These depend on the CSM outer radius, dust composition and grain size, and the properties of the progenitor. The results constrain the pre-supernova evolution of the progenitor, and the nature and origin of the observed post-explosion IR emission from SN 2010jl. In particular, an eta Car-type progenitor will require at least 4 mag of visual extinction to avoid detection by Hubble. This can be achieved with dust masses greater than approximately equal to 10(exp -3) solar mass (less than the estimated 0.2-0.5 solar mass around eta Car), which must be located at distances of greater than approximately equal to 10(exp 16) cm from the star to avoid detection by Spitzer.

Description: The modeling of X-ray spectra from photoionized astrophysical plasmas has been significantly improved due to recent advancements in the theoretical and numerical frameworks, as well as a consolidated and reliable atomic database of inner-shell transitions for all the relevant ions. We discuss these developments and the current state of X-ray spectral modeling in the context of oxygen cold absorption in the interstellar medium (ISM). Unconventionally, we use high-resolution astrophysical observations to accurately determine line positions, and adjust the theoretical models for a comprehensive interpretation of the observed X-ray spectra. This approach has brought to light standing discrepancies in the neutral oxygen absorption-line positions determined from observations and laboratory measurements. We give an overview of our current efforts to devise a definitive model of oxygen photoabsorption that can help to resolve the existing controversy regarding ISM atomic and molecular fractions.

Description: No abstract available

Description: No abstract available

Description: This payload overview presentation will be presented at the POIWG on October 17th, 2017. It provides a high-level overview of Cell Science-02 operations.

Description: No abstract available

Description: We present an investigation of long-term modulation in the X-ray light curves of five little-studied candidate high-mass X-ray binaries using the Swift Burst Alert Telescope (SWIFT-BAT). IGR J14488-5942 and AX J1700.2-4220 show strong modulation at periods of 49.6 and 44 days, respectively, which are interpreted as orbital periods of Be star systems. For IGR J14488-5942, observations with the Swift X-ray Telescope show a hint of pulsations at 33.4 seconds. For AX J1700.2-4220, 54 second-pulsations were previously found with XMM-Newton. Swift J1816.7-1613 exhibits complicated behavior. The strongest peak in the power spectrum is at a period near 150 days, but this conflicts with a determination of a period of 118.5 days by La Parola et al. AX J1820.5-1434 has been proposed to exhibit modulation near 54 days, but the extended BAT observations suggest modulation at slightly longer than double this at approximately 111 days. There appears to be a long-term change in the shape of the modulation near 111 days, which may explain the apparent discrepancy. The X-ray pulsar XTE J1906+090,which was previously proposed to be a Be star system with an orbital period of approximately 30 days from pulse timing, shows peaks in the power spectrum at 81 and 173 days. The origins of these periods are unclear, although theymight be the orbital period and a superorbital period respectively. For all five sources, the long-term variability, together with the combination of orbital and proposed pulse periods, suggests that the sources contain Be starmass donors.

Description: We present C I(21) and multi-transition C-12 O observations of a dusty star-forming galaxy, ACT J2029+0120,which we spectroscopically confirm to lie at zeta = 2.64. We detect CO(3-2), CO(5-4), CO(7-6), CO(8-7), and C I(2-1) at high significance, tentatively detect HCO+(4-3), and place strong upper limits on the integrated strength of dense gas tracers (HCN(4-3) and CS(7-6)). Multi-transition CO observations and dense gas tracers can provide valuable constraints on the molecular gas content and excitation conditions in high-redshift galaxies. We therefore use this unique data set to construct a CO spectral line energy distribution (SLED) of the source, which is most consistent with that of a ULIRG Seyfert or QSO host object in the taxonomy of the Herschel Comprehensive ULIRG Emission Survey. We employ RADEX models to fit the peak of the CO SLED, inferring a temperature of T approximately 117 K and n(sub H2) approximately 10(exp5) cm(exp -3), most consistent with a ULIRGQSO object and the presence of high-density tracers. We also find that the velocity width of the C I line is potentially larger than seen in all CO transitions forth is object, and that the L'(sub Ci(2-1))/L'(sub CO(3-2))ratio is also larger than seen in other lensed and unlensed submillimeter galaxies and QSO hosts; if confirmed, this anomaly could be an effect of differential lensing of a shocked molecular outflow.

Description: System testing of the Carbon Dioxide Removal and Compression System (CRCS) has revealed that sufficient CO2 removal capability was not achieved with the designed system. Subsystem component analysis of the zeolite bed revealed that the sorbent material suffered significant degradation and CO2 loading capacity loss. In an effort to find the root cause of this degradation, various factors were investigated to try to reproduce the observed performance loss. These factors included contamination by vacuum pump oil, o-ring vacuum grease, loading/unloading procedures, and operations. This paper details the experiments that were performed and their results.

Description: The James Webb Space Telescope (JWST) will have numerous modes for acquiring photometry and spectra of stars, planets, galaxies, and other astronomical objects over wavelengths of 0.6 - 28 microns. Several of these modes are well-suited for observing atomic and molecular features in the atmospheres of transiting or spatially resolved exoplanets. I will present basic information on JWST capabilities, highlight modes that are well-suited for observing exoplanets, and give examples of what may be learned from JWST observations. This will include simulated spectra and expected retrieved chemical abundance, composition, equilibrium, and thermal information and uncertainties. JWST Cycle 1 general observer proposals are expected to be due in March 2018 with launch in October 2018, and the greater scientific community is encouraged to propose investigations to study exoplanet atmospheres and other topics.

Description: No abstract available

Description: We present H-band scattered light imaging of a bright debris disk around the A0 star HD 36546 obtained from the Subaru Coronagraphic Extreme Adaptive Optics (SCExAO) system with data recorded by the HiCIAO camera using the vector vortex coronagraph. SCExAO traces the disk from r approximately 0 3 to r approximately 0".3 to r approximately 1" (34-114 au). The disk is oriented in a near east west direction (PA approximately 75deg), is inclined by I approximately 70deg-75deg, and is strongly forward-scattering(g greater than 0.5). It is an extended disk rather than a sharp ring; a second, diffuse dust population extends from the disks eastern side. While HD 36546 intrinsic properties are consistent with a wide age range (t approximately 1-250 Myr), its kinematics and analysis of coeval stars suggest a young age (310 Myr) and a possible connection to Taurus-Aurigas star formation history. SCExAOs planet-to-star contrast ratios are comparable to the first-light Gemini Planet Imager contrasts; for an age of 10 Myr, we rule out planets with masses comparable to HR 8799 b beyond a projected separation of 23 au. A massive icy planetesimal disk or an unseen super-Jovian planet at r greater than 20 au may explain the disks visibility. The HD 36546 debris disk may be the youngest debris disk yet imaged, is the first newly identified object from the now-operational SCExAO extreme AO system, is ideally suited for spectroscopic follow-up with SCExAO/CHARIS in 2017, and may be a key probe of icy planet formation and planet disk interactions.

Description: We present Gemini Planet Imager polarized intensity imagery of HD 100453 in Y, J, and K1 bands that reveals an inner gap (9-18 au), an outer disk (18-39 au) with two prominent spiral arms, and two azimuthally localized dark features that are also present in Spectro-Polarimetric High-contrast Exoplanet REsearch (SPHERE) total intensity images. Spectral energy distribution fitting further suggests that the radial gap extends to 1 au. The narrow, wedge-like shape of the dark features appears similar to predictions of shadows cast by an inner disk that is misaligned with respect to the outer disk. Using the Monte Carlo radiative transfer code HOCHUNCK3D, we construct a model of the disk that allows us to determine its physical properties in more detail. From the angular separation of the features, we measure the difference in inclination between the disks (45deg) and their major axes, PA = 140deg east of north for the outer disk, and 100deg for the inner disk. We find an outer-disk inclination of 25deg +/- 10deg from face-on, in broad agreement with the Wagner et al. measurement of 34deg. SPHERE data in J and H bands indicate a reddish disk, which indicates that HD 100453 is evolving into a young debris disk.

Description: We present near-infrared spectra for 144 candidate planetary systems identified during Campaigns 1-7 of the NASA K2 Mission. The goal of the survey was to characterize planets orbiting low-mass stars, but our Infrared Telescope Facility/SpeX and Palomar/TripleSpec spectroscopic observations revealed that 49% of our targets were actually giant stars or hotter dwarfs reddened by interstellar extinction. For the 72 stars with spectra consistent with classification as cool dwarfs (spectral types K3-M4), we refined their stellar properties by applying empirical relations based on stars with interferometric radius measurements. Although our revised temperatures are generally consistent with those reported in the Ecliptic Plane Input Catalog (EPIC), our revised stellar radii are typically 0.13 solar radius (39%) larger than the EPIC values, which were based on model isochrones that have been shown to underestimate the radii of cool dwarfs. Our improved stellar characterizations will enable more efficient prioritization of K2 targets for follow-up studies.

Description: We present near-infrared high-precision photometry for eight transiting hot Jupiters observed during their predicted secondary eclipses. Our observations were carried out using the staring mode of the WIRCam instrument on the Canada-France-Hawaii Telescope (CFHT).We present the observing strategies and data reduction methods which delivered time series photometry with statistical photometric precision as low as 0.11 percent. We performed a Bayesian analysis to model the eclipse parameters and systematics simultaneously. The measured planet-to-star flux ratios allowed us to constrain the thermal emission from the day side of these hot Jupiters, as we derived the planet brightness temperatures. Our results combined with previously observed eclipses reveal an excess in the brightness temperatures relative to the blackbody prediction for the equilibrium temperatures of the planets for a wide range of heat redistribution factors. We find a trend that this excess appears to be larger for planets with lower equilibrium temperatures. This may imply some additional sources of radiation, such as reflected light from the host star and/or thermal emission from residual internal heat from the formation of the planet.

Description: TRAPPIST-1 is a nearby ultra-cool dwarf that is host to a remarkable planetary system consisting of seven transiting planets. The orbital properties and radii of the planets have been well constrained, and recently, the masses of the inner six planets have been measured with additional ground- and space-based photometric observations. Large uncertainties in these mass measurements have prevented a robust analysis of the planetary compositions. Here, we perform many thousands of N-body dynamical simulations with planet properties perturbed from the observed values and identify those that are stable for millions of years. This allows us to identify self-consistent orbital solutions that can be used in future studies. From our range of dynamical masses, we find that most of the planets are consistent with an Earth-like composition, where TRAPPIST-1f is likely to have a volatile-rich envelope.

Description: The main goal of the present work is to estimate the effects of plasma environment on the atomic parameters associated with the K-vacancy states in highly charged iron ions within the astrophysical context of accretion disks around black holes. In order to do this, multiconfiguration Dirac-Fock computations have been carried out by considering a time averaged Debye-Huckel potential for both the electron-nucleus and electron-electron interactions. In the present paper, a first sample of results related to the ionization potentials, the K-thresholds, the transition energies and the radiative emission rates is reported for the ions Fe23+ and Fe24+.