ALBERT

All Library Books, journals and Electronic Records Telegrafenberg

feed icon rss

Your email was sent successfully. Check your inbox.

An error occurred while sending the email. Please try again.

Proceed reservation?

Export
Filter
  • Springer  (166)
Collection
  • 11
    Electronic Resource
    Electronic Resource
    Springer
    Histochemistry and cell biology 21 (1970), S. 369-381 
    ISSN: 1432-119X
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Description / Table of Contents: Zusammenfassung In der vorliegenden Arbeit wird ein Verfahren zur autoradiographischen Bestimmung des Zellzyklus der Erythroblasten in vitro angegeben. Die Knochenmarkzellen wurden bei +37°C in autologem oder homologem Plasma, das H3- bzw. C14-Thymidin enthielt, bei verschiedenen O2-Drücken inkubiert. Zur Bestimmung der DNS-Synthesezeit wurde das Doppelmarkierungsverfahren und zur Bestimmung der G2-Phase das „%-markierte-Mitosen-Verfahren” angewandt. Vergleichende in vivo- und in vitro-Messungen zeigten, daß bei 2,2 atü reinen O2 bei der hier angewandten in vitro-Methode das Wachstumsverhalten der Erythroblasten beim Tier und offenbar auch beim Menschen den in vivo gefundenen Werten entspricht.
    Notes: Summary This paper describes an in-vitro-method for the autoradiographical determination of the cell cycle of erythroblasts (rat, mouse, and man). The bone marrow cells were incubated (37° C) for two hours in autologous or homologous plasma containing H3- and C14-thymidine respectively. For determination of DNA synthesis time the double labeling technique, for estimation of the premitotic G2-phase the method of labeled mitoses was applied. The comparison of in vivo and in vitro measurements shows that using 2,2 atm of pure oxygen by the described in-vitro-method the cell proliferation kinetics of erythroblasts of rat, mouse, and man were approximately the same as in vivo.
    Type of Medium: Electronic Resource
    Location Call Number Expected Availability
    BibTip Others were also interested in ...
  • 12
    Electronic Resource
    Electronic Resource
    Springer
    Naturwissenschaften 73 (1986), S. 374-375 
    ISSN: 1432-1904
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Chemistry and Pharmacology , Natural Sciences in General
    Type of Medium: Electronic Resource
    Location Call Number Expected Availability
    BibTip Others were also interested in ...
  • 13
    Electronic Resource
    Electronic Resource
    Springer
    Theoretical and applied genetics 48 (1976), S. 23-34 
    ISSN: 1432-2242
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology
    Notes: Summary The course of meiosis in higher plants is controlled by a large number of genes, the function of which can be discerned by means of mutants showing any kind of meiotic anomaly. In general, there are three main groups of genes belonging to this system. The as-genes control the pairing behaviour of the homologous chromosomes, causing asynapsis in the mutated condition. The ds-genes are responsible for chiasma formation and chiasma frequency, causing desynapsis in the mutated condition. As- and ds-genes influence micro- and macrosporogenesis in a similar way but the ms-genes become effective only in microsporogenesis, resulting in a complete breakdown of meiosis at a stage specific for each gene of the group. In Pisum sativum, 58 mutants showing genetically conditioned meiotic anomalies have been cytogenetically analysed: 34 of them belong to the ds- and 7 to the as-group; one gene causes asynaptic as well as desynaptic effects; 13 genotypes are male sterile due to degeneration of the chromosomes; the remaining 3 genes cause less specific meiotic disturbances. The lethality of a mutant can be overcome by distinct environmental conditions but the mutant is sterile because of manifold meiotic anomalies. One gene in the Pisum genome controls the transition from the vegetative to the reproductive stage of the plants. Other genes influence the differentiation of the growing points in such a way that the sporogenic tissues are not formed. In these mutants, no sporocytes are present which can undergo meiosis. From the findings available for many species of the plant kingdom, it can be assumed that hundreds of genes controlling meiosis are present in the genome of each higher plant.
    Type of Medium: Electronic Resource
    Location Call Number Expected Availability
    BibTip Others were also interested in ...
  • 14
    Electronic Resource
    Electronic Resource
    Springer
    Theoretical and applied genetics 48 (1976), S. 227-235 
    ISSN: 1432-2242
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology
    Description / Table of Contents: Zusammenfassung In konjugationsgestörten Mutanten treten im Verlaufe der Meiosis Univalente oder Univalente und Bivalente in wechselnden Häufigkeitsverhältnissen zueinander auf. Ihre räumliche Anordnung im Spindelraum der Metaphase I wurde zytologisch untersucht und die Befunde statistisch ausgewertet. Der überwiegende Teil unseres Materials ließ sich einheitlich durch eine Polya-Verteilung charakterisieren. Für deren Parameter wurden — für jeden Genotyp und für jede Univalentenklasse getrennt —Punkt-und Intervallschätzungen nach der Maximum Likelihood-Methode durchgeführt. Aus der Lage der Schätzwerte konnten wir schließen, daß bei allen untersuchten Mutanten die Wahrscheinlichkeit für die Univalente, sich in der Metaphaseplatte einzuordnen, um so größer wird, je mehr Bivalente in der Zelle vorliegen. Die gegenseitige Beeinflussung der Univalente ist bei unseren Mutanten unterschiedlich. Bei einer geringen Anzahl von Bivalenten erhöht jedes zufällig in der Metaphaseplatte angeordnete Univalent die Wahrscheinlichkeit für die übrigen, sich ebenfalls dort einzuordnen. Ist die Zahl der Bivalente erhöht, so nimmt die gegenseitige Beeinflussung der Univalente in einigen Fällen ab, in anderen Fällen bleibt sie lediglich erhalten. Es wurde zum Schluß versucht, die erarbeiteten Befunde als univalentenbedingte strukturelle und funktioneile Änderungen im Aufbau des Spindelapparates zu erklären.
    Notes: Summary Asynaptic and desynaptic mutants are characterized by the appearance of univalents in the course of meiosis. Their spatial arrangement in the spindle apparatus of metaphase I was cytologically investigated and the findings were statistically analysed. The great majority of our material could be fitted to a Polya-distribution. For the parameters of this distribution, point- and intervalestimations were performed by the maximum likelihood method, separately for each genotype and each univalent class. From the position of the estimates in the different classes, it can be concluded that in all genotypes under consideration a high number of bivalents increases the probability of the remaining univalents being arranged in the metaphase plate. The mutual interference of the univalents themselves differs from genotype to genotype: when the number of bivalents is low, each univalent that happens to be arranged in the metaphase plate raises the probability that the remaining univalents will migrate into the metaphase plate, too. In some cases, the mutual interference of the univalents is reduced when the number of bivalents increases; in other cases this interference is merely maintained. Finally, we tried to interpret the cytological and statistical findings by structural and functional changes of the spindle apparatus brought about by the existence of univalents.
    Type of Medium: Electronic Resource
    Location Call Number Expected Availability
    BibTip Others were also interested in ...
  • 15
    Electronic Resource
    Electronic Resource
    Springer
    Naturwissenschaften 31 (1943), S. 277-278 
    ISSN: 1432-1904
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Chemistry and Pharmacology , Natural Sciences in General
    Type of Medium: Electronic Resource
    Location Call Number Expected Availability
    BibTip Others were also interested in ...
  • 16
    Electronic Resource
    Electronic Resource
    Springer
    Oecologia 33 (1978), S. 203-208 
    ISSN: 1432-1939
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology
    Notes: Summary SO2-fumigation experiments were conducted with plants of pea (Pisum sativum) and corn (Zea mays) recognized to be, respectively, sensitive and tolerant to the gas. Accumulation of inorganic sulfur in the tissues revealed that the pea takes up considerably greater amounts of SO2 than corn. Porometer measurements and transpiration coefficients show that this greater SO2 uptake is partly related to the lower leaf diffusion resistance of peas. Additional internal sinks for SO2 uptake are discussed in order to give a complete explanation of the differential SO2 uptake of the two species.
    Type of Medium: Electronic Resource
    Location Call Number Expected Availability
    BibTip Others were also interested in ...
  • 17
    Electronic Resource
    Electronic Resource
    Springer
    Naturwissenschaften 71 (1984), S. 381-383 
    ISSN: 1432-1904
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Chemistry and Pharmacology , Natural Sciences in General
    Type of Medium: Electronic Resource
    Location Call Number Expected Availability
    BibTip Others were also interested in ...
  • 18
    Electronic Resource
    Electronic Resource
    Springer
    Naturwissenschaften 57 (1970), S. 456-456 
    ISSN: 1432-1904
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Chemistry and Pharmacology , Natural Sciences in General
    Type of Medium: Electronic Resource
    Location Call Number Expected Availability
    BibTip Others were also interested in ...
  • 19
    Electronic Resource
    Electronic Resource
    Springer
    Histochemistry and cell biology 4 (1964), S. 238-251 
    ISSN: 1432-119X
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Notes: Zusammenfassung 1. Es wird die Verteilung des den Pentosephosphat-Cyclus einleitenden Fermentes Glukose-6-phosphat-Dehydrogenase in den verschiedenen Strukturen gesunder Organe beschrieben und nach Organsystemen gegliedert in Tabellenform wiedergegeben. 2. Die stärkste Enzymaktivität ist im Epithelgewebe, in den Drüsen mit innerer Sekretion und in Gliazellen des Nervensystems festzustellen. 3. Die Bedeutung des Pentosephosphat-Cyclus für die Bereitstellung von Ribose und TPNH-abhängiger Synthesen wird am Beispiel des enzymaktiven Epithelgewebes und der ebenfalls fermentaktiven Drüsen mit innerer Sekretion besprochen.
    Type of Medium: Electronic Resource
    Location Call Number Expected Availability
    BibTip Others were also interested in ...
  • 20
    Electronic Resource
    Electronic Resource
    Springer
    Human genetics 〈Berlin〉 28 (1975), S. 217-220 
    ISSN: 1432-1203
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Description / Table of Contents: Zusammenfassung Eine Familie mit 2 autoptisch gesicherten Neuroblastomen, einem Ganglioneuroblastom und Hinweisen auf 3 weitere Neuroblastome wurde cytogenetisch untersucht. Anlaß war der von Sandberg et al. (1972) mitgeteilte Befund von double-minute-Chromosomen in Lymphocyten des peripheren Blutes bei einem Neuroblastom. Die Untersuchung sollte klären, ob in dieser “Neuroblastom-Familie” eine chromosomale Aberration als erbliche Vorschädigung die Entstehung von Sympathicustumoren begüngstigt. Es fanden sich keine konstanten Chromosomenanomalien, auch keine double-minute-Chromosomen.
    Notes: Summary A cytogenetic investigation was performed in a family which included 2 individuals with congential neuroblastomas of the suprarenal gland confirmed by autopsy and one with a ganglioneuroblastoma of the thoracic wall as well as 3 other individuals with tumors which probably were also neuroblastomas. The lymphocytes of the peripheral blood of 5 healthy relatives as well as of the child with the treated ganglioneuroblastoma failed to show a constant alteration of chromosomes. In this family, therefore, the suggestion could not be proofed that the very rate familial aggregation of neuroblastomas is caused by a hereditary chromosomal aberration.
    Type of Medium: Electronic Resource
    Location Call Number Expected Availability
    BibTip Others were also interested in ...
Close ⊗
This website uses cookies and the analysis tool Matomo. More information can be found here...