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  • 2020-2023  (41)
  • 1980-1984  (1,566)
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  • 1
    Call number: MOP B 17531 ; MOP B 17600
    Type of Medium: Monograph available for loan
    Pages: 220 S. : Ill.
    Edition: 2., unveränd. Aufl.
    Location: MOP - must be ordered
    Location: MOP - must be ordered
    Branch Library: GFZ Library
    Branch Library: GFZ Library
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  • 2
    Publication Date: 2022-03-23
    Description: The Eastern Boundary Current is an essential part of the water mass exchange between the subtropical and subpolar North Atlantic. Here, we study the offshore branch of the European Shelf Current (ESC) over the Goban Spur slope area off Ireland. Our analysis is based on current measurements obtained from a multiyear mooring effort, complemented by ship‐board observations along a hydrographic section, satellite‐derived estimates of absolute dynamic topography with geostrophic currents, and float trajectories. These data serve to quantify the offshore branch of the ESC on intraannual to interannual timescales. From the moored observations, we derive a mean poleward along‐slope volume flux of 3.7 ± 0.7 Sv for the period 2017–2019. Using a multilinear regression model and geostrophic surface velocities, we extend the time series to the period 1993–2019 and obtain a long‐term mean transport of 3.2 ± 0.4 Sv. Both time series show strong variability ranging from −7.5 to 15.7 Sv. The variability is linked to a dynamic eddy field, especially a stationary cyclonic circulation pattern near the mooring array, and meandering of current branches originating from the North Atlantic Current. We find no evidence of a consistent deep boundary current extending from the shelf break to the position of the offshore mooring (4,500 m depth), but confirm a persistent along‐slope flow at the shallower slope (1,500 m depth). Geostrophic surface velocities and float trajectories reveal that the offshore branch of the ESC does not follow a clear northward path from the eastern subtropical regions but rather indicate the intermittent character of the flow.
    Description: Plain Language Summary: In this study, we describe the European Shelf Current (ESC) in the eastern North Atlantic. The study area is the deeper part of the Goban Spur area off Ireland. We use current measurements of instruments deployed in the water column from 2016 to 2019 combined with satellite observations of surface circulation and drifting float paths. We aim to quantify the contribution of the offshore branch to the ESC system. We calculate a poleward volume transport following the slope that is on average 3.7 ± 0.7 Sverdrup (Sv; 1 Sv = 1 million cubic meter per second) for the period 2017–2019. We use a mathematical relation between mooring data and satellite observations to extend the time series to the period 1993–2019 and obtain an average transport of 3.2 ± 0.4 Sv. There occur strong changes over time ranging from −5 to 15 Sv. These changes are caused by rotating vortices (eddies), especially a counter‐clockwise rotating circulation pattern near the moorings, and changing positions of currents branching from the North Atlantic Current. We find that the offshore branch of the ESC does not follow a clear northward path from the eastern subtropical regions of the North Atlantic. Instead, the flow is of rather unsteady character.
    Description: Key Points: The analysis of multiplatform observational efforts is used to study the circulation at the North Atlantic Eastern Boundary. The volume transport of the offshore branch of the European Shelf Current is on average 3.2 ± 0.4 Sv for the period 1993–2019. Transport variability is in the range of −7.5–15.7 Sv and induced by eddies and meandering North Atlantic Current branches.
    Description: Bundesministerium für Bildung und Forschung (BMBF) http://dx.doi.org/10.13039/501100002347
    Description: Deutsche Forschungsgemeinschaft (DFG) http://dx.doi.org/10.13039/501100001659
    Keywords: ddc:551.46
    Language: English
    Type: doc-type:article
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  • 3
    Electronic Resource
    Electronic Resource
    Springer
    Immunogenetics 16 (1982), S. 181-184 
    ISSN: 1432-1211
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Type of Medium: Electronic Resource
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  • 4
    ISSN: 1432-1211
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Notes: Abstract Previously we have reported that two sublines of the YAC lymphoma selected for reduced expression of H-2a and Moloney-virus determined cell-surface (MCSA) antigens are, in contrast to YAC, allotransplantable in H-2-incompatible recipients, and resistant to rejection by preimmunized semisyngeneic hosts. A third YAC variant with reduced MCSA but unchanged H-2-antigen expression, was not allotransplantable and showed only a slight decrease in its immunosensitivity in preimmunized semisyngeneic hosts in vivo. This suggested that H-2-antigen expression may be more important than MCSA expression for recognition and rejection by semisyngeneic mice. We have now tested the sublines expressing low H-2a for their in vitro sensitivity to humoral and cell-mediated lysis. — The variants were more resistant than YAC to complement lysis by anti-H-2a, anti-MCSA, anti-Thy 1.2 and antispecies sera. Absorption tests with antispecies serum indicated that the decreased cytolytic sensitivity of the variants was not related to the concentration of the relevant antigens, which was similar to that of the original YAC tumor. As expected from the low amount of H-2a the variants showed a decreased sensitivity to the killing effect of allogeneic cytotoxic T lymphocytes (CTL). They were also lysed to a lesser extent than YAC by semisyngeneic CTL, probably directed against virally determined antigens. However, they were also less sensitive to lysis by natural killer (NK) cells, although NK lysis is probably unrelated to MHC expression. In conclusion, our selection for reduced H-2-expression appears to have resulted in the isolation of variants with a generally increased resistance to various humoral and cell-mediated lytic functions.
    Type of Medium: Electronic Resource
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  • 5
    Electronic Resource
    Electronic Resource
    Springer
    Immunogenetics 16 (1982), S. 285-317 
    ISSN: 1432-1211
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Notes: Abstract The downpour of information about the H-2 complex has hit immunology with the force of a tropical rainstorm. It is flooding whole fields, uprooting carefully cultivated orchards, displacing cottages, houses, and palaces, threatening to drown their inhabitants. This and the following article (Klein et al. 1982) are meant to serve as kinds of life-savers for those who have not learned how to swim in the rapid and murky waters. The First Listing, published four years ago (Klein et al. 1978), consisted only of tables; to this Second Listing we have added a brief description of all the loci residing, or thought to be residing, on the mouse chromosome 17, the chromosome carrying the H-2 complex. This arrangement necessitated the division of the Second Listing into two parts, the first part concerned with loci on chromosome 17 outside of the H-2 complex and the second part dealing with the complex itself. The discussion of the individual loci is prefaced by a description of the chromosome.
    Type of Medium: Electronic Resource
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  • 6
    ISSN: 1432-1211
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Notes: Abstract YAC is a Moloney-virus-induced lymphoma of strain A/Sn origin that is highly sensitive to natural killing (NK) in vitro and NK-mediated hybrid resistance in vivo. Previous studies have shown that hybrid resistance is under polygenic control that includes bothH-2-linked and non-H-2-linked factors. For further analysis on the genetics and immunology of hybrid resistance, we are at present developing congenic resistant lines on an A/Sn strain background. Following an outcross to a strain that conveys strong hybrid resistance on the F1 offspring, the mice are challenged with small viable inocula of YAC. Survivors are backcrossed to A/Sn. This is followed by repeated YAC challenge and backcrossing. We now report the successful establishment of a first resistant strain, designated A.LRA. It is relatively resistant to small inocula of YAC cells due to a single, non-H-2-linked dominant gene introduced from the C57L strain.
    Type of Medium: Electronic Resource
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  • 7
    Electronic Resource
    Electronic Resource
    Springer
    Immunogenetics 16 (1982), S. 319-328 
    ISSN: 1432-1211
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Notes: Abstract One hundred and four H-2 congenic lines were typed for alleles at seven loci, Qa-1, Qa-2, Tla, C3, Ce-2, Pgk-2, and Upg-1, residing distal to the H-2 complex. The results of the typing were used to estimate the length of the segment of chromosome 17 derived from the donor strain of each line—that is, the minimal length of the differential segment. The results indicate that only lines derived by intra-H-2 crossing-over in such a way that they inherited the right-hand portion of H-2 from the inbred partner have the telomeric half of chromosome 17 identical with that of the inbred-partner strain. In other lines the differential segment is at least 3 to 10 cM long. It is argued that in some lines the entire telomeric half of chromosome 17 might be of donor-strain origin.
    Type of Medium: Electronic Resource
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  • 8
    Electronic Resource
    Electronic Resource
    Oxford, UK : Blackwell Publishing Ltd
    International journal of immunogenetics 7 (1980), S. 0 
    ISSN: 1744-313X
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Biology , Medicine
    Notes: Mouse strains differ widely in their natural killer(NK)-cell activity. In the (A X B6) X A backcross, high reactivity was linked to H-2b, although non-H-2-linked genes were also demonstrated (Petranyi et al., 1975). Harmon et al. (1977) demonstrated an H-2Dd-associated reactivity gene (1977). In the present study, we have tested eleven B10 congenic strains for NK activity. The H-2Dd strains B10.A, B10.T(6R), B10.S(7R), B10.HTT and B10.D2 were more highly reactive than B10, B10.S, B10.G, B10.A(2R) and B10.BR, which do not carry the d allele at the H-2D locus. While this confirms the H-2Dd association of a reactivity gene, an exception was found in the B10.A(5R) strain that was low reactive in spite of the fact that it carries H-2Dd. This suggests the possibility that the H-2Dd-associated gene is outside H-2, to the right of Tla.The AKR.H-2b congenic line had the same low activity as the AKR.H-2k strain; both were much lower than B6. This suggests either one of two possibilities: the H-2b-linked reactivity gene is relatively distant from the H-2 complex, although localized on chromosome 17 or alternatively, if localized within or in the close neighbourhood of H-2, it requires non-H-2 genes for full expression.Previously, we have shown that the B6 X DBA/2 F1 hybrid was more highly reactive than either one of its two parental strains (Klein et al., 1978). A similar complementation effect is described in the present paper for the B10.D2 congenic strain. The high reactivity of this line can be due to the combined effect of an H-2b-linked gene from DBA/2 and the non-H-2 background of B10 or, alternatively, the former, together with an H-2b-linked gene from B6 that lies well outside outside the H-2 locus itself.
    Type of Medium: Electronic Resource
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  • 9
    Electronic Resource
    Electronic Resource
    [s.l.] : Nature Publishing Group
    Nature 288 (1980), S. 594-596 
    ISSN: 1476-4687
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Chemistry and Pharmacology , Medicine , Natural Sciences in General , Physics
    Notes: [Auszug] The agarose microdroplet technique14 was used in two systems: migration inhibition induced by phytohaemagglutinin (PHA) and LMI of leukocytes from Epstein-Barr virus (EBV)-seropositive donors after exposure to EBV antigens. Washed buffy coat cells (20xl06) were mixed with 135 ? nutrient agarose ...
    Type of Medium: Electronic Resource
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  • 10
    ISSN: 1476-4687
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Chemistry and Pharmacology , Medicine , Natural Sciences in General , Physics
    Notes: [Auszug] The benzpyrene-induced EL-4 and the Rad-LV-induced P-52-127-166 leukaemias of C57BL/6 origin, are both highly resisted by certain C57BL FI hybrids that have high NK activity in vitro14,15. Also, low-dose inocula of the in vivo maintained ascites lines of the two leukaemias behaved similarly; ...
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