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  • American Association for the Advancement of Science (AAAS)  (5)
  • Oxford University Press  (3)
  • Nature Publishing Group (NPG)  (2)
  • American Chemical Society (ACS)
  • 2010-2014
  • 2005-2009  (10)
  • 2009  (10)
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  • 2010-2014
  • 2005-2009  (10)
Year
  • 1
    Publication Date: 2009-10-30
    Description: A cornerstone of Einstein's special relativity is Lorentz invariance-the postulate that all observers measure exactly the same speed of light in vacuum, independent of photon-energy. While special relativity assumes that there is no fundamental length-scale associated with such invariance, there is a fundamental scale (the Planck scale, l(Planck) approximately 1.62 x 10(-33) cm or E(Planck) = M(Planck)c(2) approximately 1.22 x 10(19) GeV), at which quantum effects are expected to strongly affect the nature of space-time. There is great interest in the (not yet validated) idea that Lorentz invariance might break near the Planck scale. A key test of such violation of Lorentz invariance is a possible variation of photon speed with energy. Even a tiny variation in photon speed, when accumulated over cosmological light-travel times, may be revealed by observing sharp features in gamma-ray burst (GRB) light-curves. Here we report the detection of emission up to approximately 31 GeV from the distant and short GRB 090510. We find no evidence for the violation of Lorentz invariance, and place a lower limit of 1.2E(Planck) on the scale of a linear energy dependence (or an inverse wavelength dependence), subject to reasonable assumptions about the emission (equivalently we have an upper limit of l(Planck)/1.2 on the length scale of the effect). Our results disfavour quantum-gravity theories in which the quantum nature of space-time on a very small scale linearly alters the speed of light.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Abdo, A A -- Ackermann, M -- Ajello, M -- Asano, K -- Atwood, W B -- Axelsson, M -- Baldini, L -- Ballet, J -- Barbiellini, G -- Baring, M G -- Bastieri, D -- Bechtol, K -- Bellazzini, R -- Berenji, B -- Bhat, P N -- Bissaldi, E -- Bloom, E D -- Bonamente, E -- Bonnell, J -- Borgland, A W -- Bouvier, A -- Bregeon, J -- Brez, A -- Briggs, M S -- Brigida, M -- Bruel, P -- Burgess, J M -- Burnett, T H -- Caliandro, G A -- Cameron, R A -- Caraveo, P A -- Casandjian, J M -- Cecchi, C -- Celik, O -- Chaplin, V -- Charles, E -- Cheung, C C -- Chiang, J -- Ciprini, S -- Claus, R -- Cohen-Tanugi, J -- Cominsky, L R -- Connaughton, V -- Conrad, J -- Cutini, S -- Dermer, C D -- de Angelis, A -- de Palma, F -- Digel, S W -- Dingus, B L -- do Couto E Silva, E -- Drell, P S -- Dubois, R -- Dumora, D -- Farnier, C -- Favuzzi, C -- Fegan, S J -- Finke, J -- Fishman, G -- Focke, W B -- Foschini, L -- Fukazawa, Y -- Funk, S -- Fusco, P -- Gargano, F -- Gasparrini, D -- Gehrels, N -- Germani, S -- Gibby, L -- Giebels, B -- Giglietto, N -- Giordano, F -- Glanzman, T -- Godfrey, G -- Granot, J -- Greiner, J -- Grenier, I A -- Grondin, M-H -- Grove, J E -- Grupe, D -- Guillemot, L -- Guiriec, S -- Hanabata, Y -- Harding, A K -- Hayashida, M -- Hays, E -- Hoversten, E A -- Hughes, R E -- Johannesson, G -- Johnson, A S -- Johnson, R P -- Johnson, W N -- Kamae, T -- Katagiri, H -- Kataoka, J -- Kawai, N -- Kerr, M -- Kippen, R M -- Knodlseder, J -- Kocevski, D -- Kouveliotou, C -- Kuehn, F -- Kuss, M -- Lande, J -- Latronico, L -- Lemoine-Goumard, M -- Longo, F -- Loparco, F -- Lott, B -- Lovellette, M N -- Lubrano, P -- Madejski, G M -- Makeev, A -- Mazziotta, M N -- McBreen, S -- McEnery, J E -- McGlynn, S -- Meszaros, P -- Meurer, C -- Michelson, P F -- Mitthumsiri, W -- Mizuno, T -- Moiseev, A A -- Monte, C -- Monzani, M E -- Moretti, E -- Morselli, A -- Moskalenko, I V -- Murgia, S -- Nakamori, T -- Nolan, P L -- Norris, J P -- Nuss, E -- Ohno, M -- Ohsugi, T -- Omodei, N -- Orlando, E -- Ormes, J F -- Ozaki, M -- Paciesas, W S -- Paneque, D -- Panetta, J H -- Parent, D -- Pelassa, V -- Pepe, M -- Pesce-Rollins, M -- Petrosian, V -- Piron, F -- Porter, T A -- Preece, R -- Raino, S -- Ramirez-Ruiz, E -- Rando, R -- Razzano, M -- Razzaque, S -- Reimer, A -- Reimer, O -- Reposeur, T -- Ritz, S -- Rochester, L S -- Rodriguez, A Y -- Roth, M -- Ryde, F -- Sadrozinski, H F-W -- Sanchez, D -- Sander, A -- Saz Parkinson, P M -- Scargle, J D -- Schalk, T L -- Sgro, C -- Siskind, E J -- Smith, D A -- Smith, P D -- Spandre, G -- Spinelli, P -- Stamatikos, M -- Stecker, F W -- Strickman, M S -- Suson, D J -- Tajima, H -- Takahashi, H -- Takahashi, T -- Tanaka, T -- Thayer, J B -- Thayer, J G -- Thompson, D J -- Tibaldo, L -- Toma, K -- Torres, D F -- Tosti, G -- Troja, E -- Uchiyama, Y -- Uehara, T -- Usher, T L -- van der Horst, A J -- Vasileiou, V -- Vilchez, N -- Vitale, V -- von Kienlin, A -- Waite, A P -- Wang, P -- Wilson-Hodge, C -- Winer, B L -- Wood, K S -- Wu, X F -- Yamazaki, R -- Ylinen, T -- Ziegler, M -- England -- Nature. 2009 Nov 19;462(7271):331-4. doi: 10.1038/nature08574. Epub 2009 Oct 28.〈br /〉〈span class="detail_caption"〉Author address: 〈/span〉Space Science Division, Naval Research Laboratory, Washington, District of Columbia 20375, USA.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/19865083" target="_blank"〉PubMed〈/a〉
    Print ISSN: 0028-0836
    Electronic ISSN: 1476-4687
    Topics: Biology , Chemistry and Pharmacology , Medicine , Natural Sciences in General , Physics
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  • 2
    Publication Date: 2009-09-18
    Description: The stability of the Wnt pathway transcription factor beta-catenin is tightly regulated by the multi-subunit destruction complex. Deregulated Wnt pathway activity has been implicated in many cancers, making this pathway an attractive target for anticancer therapies. However, the development of targeted Wnt pathway inhibitors has been hampered by the limited number of pathway components that are amenable to small molecule inhibition. Here, we used a chemical genetic screen to identify a small molecule, XAV939, which selectively inhibits beta-catenin-mediated transcription. XAV939 stimulates beta-catenin degradation by stabilizing axin, the concentration-limiting component of the destruction complex. Using a quantitative chemical proteomic approach, we discovered that XAV939 stabilizes axin by inhibiting the poly-ADP-ribosylating enzymes tankyrase 1 and tankyrase 2. Both tankyrase isoforms interact with a highly conserved domain of axin and stimulate its degradation through the ubiquitin-proteasome pathway. Thus, our study provides new mechanistic insights into the regulation of axin protein homeostasis and presents new avenues for targeted Wnt pathway therapies.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Huang, Shih-Min A -- Mishina, Yuji M -- Liu, Shanming -- Cheung, Atwood -- Stegmeier, Frank -- Michaud, Gregory A -- Charlat, Olga -- Wiellette, Elizabeth -- Zhang, Yue -- Wiessner, Stephanie -- Hild, Marc -- Shi, Xiaoying -- Wilson, Christopher J -- Mickanin, Craig -- Myer, Vic -- Fazal, Aleem -- Tomlinson, Ronald -- Serluca, Fabrizio -- Shao, Wenlin -- Cheng, Hong -- Shultz, Michael -- Rau, Christina -- Schirle, Markus -- Schlegl, Judith -- Ghidelli, Sonja -- Fawell, Stephen -- Lu, Chris -- Curtis, Daniel -- Kirschner, Marc W -- Lengauer, Christoph -- Finan, Peter M -- Tallarico, John A -- Bouwmeester, Tewis -- Porter, Jeffery A -- Bauer, Andreas -- Cong, Feng -- England -- Nature. 2009 Oct 1;461(7264):614-20. doi: 10.1038/nature08356. Epub 2009 Sep 16.〈br /〉〈span class="detail_caption"〉Author address: 〈/span〉Novartis Institutes for Biomedical Research, 250 Massachusetts Avenue, Cambridge, Massachusetts 02139, USA.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/19759537" target="_blank"〉PubMed〈/a〉
    Keywords: Axin Protein ; Cell Division/drug effects ; Cell Line ; Cell Line, Tumor ; Colorectal Neoplasms/drug therapy/metabolism ; Heterocyclic Compounds, 3-Ring/pharmacology ; Humans ; Proteasome Endopeptidase Complex/metabolism ; Protein Binding ; Proteomics ; Repressor Proteins/chemistry/*metabolism ; Signal Transduction/*drug effects ; Tankyrases/*antagonists & inhibitors/metabolism ; Transcription, Genetic/drug effects ; Ubiquitin/metabolism ; Ubiquitination ; Wnt Proteins/*antagonists & inhibitors/metabolism ; beta Catenin/antagonists & inhibitors/metabolism
    Print ISSN: 0028-0836
    Electronic ISSN: 1476-4687
    Topics: Biology , Chemistry and Pharmacology , Medicine , Natural Sciences in General , Physics
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  • 3
    Publication Date: 2009-07-04
    Description: Pulsars are rapidly rotating, highly magnetized neutron stars emitting radiation across the electromagnetic spectrum. Although there are more than 1800 known radio pulsars, until recently only seven were observed to pulse in gamma rays, and these were all discovered at other wavelengths. The Fermi Large Area Telescope (LAT) makes it possible to pinpoint neutron stars through their gamma-ray pulsations. We report the detection of 16 gamma-ray pulsars in blind frequency searches using the LAT. Most of these pulsars are coincident with previously unidentified gamma-ray sources, and many are associated with supernova remnants. Direct detection of gamma-ray pulsars enables studies of emission mechanisms, population statistics, and the energetics of pulsar wind nebulae and supernova remnants.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Abdo, A A -- Ackermann, M -- Ajello, M -- Anderson, B -- Atwood, W B -- Axelsson, M -- Baldini, L -- Ballet, J -- Barbiellini, G -- Baring, M G -- Bastieri, D -- Baughman, B M -- Bechtol, K -- Bellazzini, R -- Berenji, B -- Bignami, G F -- Blandford, R D -- Bloom, E D -- Bonamente, E -- Borgland, A W -- Bregeon, J -- Brez, A -- Brigida, M -- Bruel, P -- Burnett, T H -- Caliandro, G A -- Cameron, R A -- Caraveo, P A -- Casandjian, J M -- Cecchi, C -- Celik, O -- Chekhtman, A -- Cheung, C C -- Chiang, J -- Ciprini, S -- Claus, R -- Cohen-Tanugi, J -- Conrad, J -- Cutini, S -- Dermer, C D -- de Angelis, A -- de Luca, A -- de Palma, F -- Digel, S W -- Dormody, M -- do Couto e Silva, E -- Drell, P S -- Dubois, R -- Dumora, D -- Farnier, C -- Favuzzi, C -- Fegan, S J -- Fukazawa, Y -- Funk, S -- Fusco, P -- Gargano, F -- Gasparrini, D -- Gehrels, N -- Germani, S -- Giebels, B -- Giglietto, N -- Giommi, P -- Giordano, F -- Glanzman, T -- Godfrey, G -- Grenier, I A -- Grondin, M-H -- Grove, J E -- Guillemot, L -- Guiriec, S -- Gwon, C -- Hanabata, Y -- Harding, A K -- Hayashida, M -- Hays, E -- Hughes, R E -- Johannesson, G -- Johnson, R P -- Johnson, T J -- Johnson, W N -- Kamae, T -- Katagiri, H -- Kataoka, J -- Kawai, N -- Kerr, M -- Knodlseder, J -- Kocian, M L -- Kuss, M -- Lande, J -- Latronico, L -- Lemoine-Goumard, M -- Longo, F -- Loparco, F -- Lott, B -- Lovellette, M N -- Lubrano, P -- Madejski, G M -- Makeev, A -- Marelli, M -- Mazziotta, M N -- McConville, W -- McEnery, J E -- Meurer, C -- Michelson, P F -- Mitthumsiri, W -- Mizuno, T -- Monte, C -- Monzani, M E -- Morselli, A -- Moskalenko, I V -- Murgia, S -- Nolan, P L -- Norris, J P -- Nuss, E -- Ohsugi, T -- Omodei, N -- Orlando, E -- Ormes, J F -- Paneque, D -- Parent, D -- Pelassa, V -- Pepe, M -- Pesce-Rollins, M -- Pierbattista, M -- Piron, F -- Porter, T A -- Primack, J R -- Raino, S -- Rando, R -- Ray, P S -- Razzano, M -- Rea, N -- Reimer, A -- Reimer, O -- Reposeur, T -- Ritz, S -- Rochester, L S -- Rodriguez, A Y -- Romani, R W -- Ryde, F -- Sadrozinski, H F-W -- Sanchez, D -- Sander, A -- Saz Parkinson, P M -- Scargle, J D -- Sgro, C -- Siskind, E J -- Smith, D A -- Smith, P D -- Spandre, G -- Spinelli, P -- Starck, J-L -- Strickman, M S -- Suson, D J -- Tajima, H -- Takahashi, H -- Takahashi, T -- Tanaka, T -- Thayer, J G -- Thompson, D J -- Tibaldo, L -- Tibolla, O -- Torres, D F -- Tosti, G -- Tramacere, A -- Uchiyama, Y -- Usher, T L -- Van Etten, A -- Vasileiou, V -- Vilchez, N -- Vitale, V -- Waite, A P -- Wang, P -- Watters, K -- Winer, B L -- Wolff, M T -- Wood, K S -- Ylinen, T -- Ziegler, M -- New York, N.Y. -- Science. 2009 Aug 14;325(5942):840-4. doi: 10.1126/science.1175558. Epub 2009 Jul 2.〈br /〉〈span class="detail_caption"〉Author address: 〈/span〉Space Science Division, Naval Research Laboratory, Washington, DC 20375, USA.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/19574346" target="_blank"〉PubMed〈/a〉
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
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  • 4
    Publication Date: 2009-07-04
    Description: Pulsars are born with subsecond spin periods and slow by electromagnetic braking for several tens of millions of years, when detectable radiation ceases. A second life can occur for neutron stars in binary systems. They can acquire mass and angular momentum from their companions, to be spun up to millisecond periods and begin radiating again. We searched Fermi Large Area Telescope data for pulsations from all known millisecond pulsars (MSPs) outside of globular clusters, using rotation parameters from radio telescopes. Strong gamma-ray pulsations were detected for eight MSPs. The gamma-ray pulse profiles and spectral properties resemble those of young gamma-ray pulsars. The basic emission mechanism seems to be the same for MSPs and young pulsars, with the emission originating in regions far from the neutron star surface.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Abdo, A A -- Ackermann, M -- Ajello, M -- Atwood, W B -- Axelsson, M -- Baldini, L -- Ballet, J -- Barbiellini, G -- Baring, M G -- Bastieri, D -- Baughman, B M -- Bechtol, K -- Bellazzini, R -- Berenji, B -- Bignami, G F -- Blandford, R D -- Bloom, E D -- Bonamente, E -- Borgland, A W -- Bregeon, J -- Brez, A -- Brigida, M -- Bruel, P -- Burnett, T H -- Caliandro, G A -- Cameron, R A -- Camilo, F -- Caraveo, P A -- Carlson, P -- Casandjian, J M -- Cecchi, C -- Celik, O -- Charles, E -- Chekhtman, A -- Cheung, C C -- Chiang, J -- Ciprini, S -- Claus, R -- Cognard, I -- Cohen-Tanugi, J -- Cominsky, L R -- Conrad, J -- Corbet, R -- Cutini, S -- Dermer, C D -- Desvignes, G -- de Angelis, A -- de Luca, A -- de Palma, F -- Digel, S W -- Dormody, M -- do Couto e Silva, E -- Drell, P S -- Dubois, R -- Dumora, D -- Edmonds, Y -- Farnier, C -- Favuzzi, C -- Fegan, S J -- Focke, W B -- Frailis, M -- Freire, P C C -- Fukazawa, Y -- Funk, S -- Fusco, P -- Gargano, F -- Gasparrini, D -- Gehrels, N -- Germani, S -- Giebels, B -- Giglietto, N -- Giordano, F -- Glanzman, T -- Godfrey, G -- Grenier, I A -- Grondin, M H -- Grove, J E -- Guillemot, L -- Guiriec, S -- Hanabata, Y -- Harding, A K -- Hayashida, M -- Hays, E -- Hobbs, G -- Hughes, R E -- Johannesson, G -- Johnson, A S -- Johnson, R P -- Johnson, T J -- Johnson, W N -- Johnston, S -- Kamae, T -- Katagiri, H -- Kataoka, J -- Kawai, N -- Kerr, M -- Knodlseder, J -- Kocian, M L -- Kramer, M -- Kuss, M -- Lande, J -- Latronico, L -- Lemoine-Goumard, M -- Longo, F -- Loparco, F -- Lott, B -- Lovellette, M N -- Lubrano, P -- Madejski, G M -- Makeev, A -- Manchester, R N -- Marelli, M -- Mazziotta, M N -- McConville, W -- McEnery, J E -- McLaughlin, M A -- Meurer, C -- Michelson, P F -- Mitthumsiri, W -- Mizuno, T -- Moiseev, A A -- Monte, C -- Monzani, M E -- Morselli, A -- Moskalenko, I V -- Murgia, S -- Nolan, P L -- Norris, J P -- Nuss, E -- Ohsugi, T -- Omodei, N -- Orlando, E -- Ormes, J F -- Paneque, D -- Panetta, J H -- Parent, D -- Pelassa, V -- Pepe, M -- Pesce-Rollins, M -- Piron, F -- Porter, T A -- Raino, S -- Rando, R -- Ransom, S M -- Ray, P S -- Razzano, M -- Rea, N -- Reimer, A -- Reimer, O -- Reposeur, T -- Ritz, S -- Rochester, L S -- Rodriguez, A Y -- Romani, R W -- Roth, M -- Ryde, F -- Sadrozinski, H F W -- Sanchez, D -- Sander, A -- Saz Parkinson, P M -- Scargle, J D -- Schalk, T L -- Sgro, C -- Siskind, E J -- Smith, D A -- Smith, P D -- Spandre, G -- Spinelli, P -- Stappers, B W -- Starck, J L -- Striani, E -- Strickman, M S -- Suson, D J -- Tajima, H -- Takahashi, H -- Tanaka, T -- Thayer, J B -- Thayer, J G -- Theureau, G -- Thompson, D J -- Thorsett, S E -- Tibaldo, L -- Torres, D F -- Tosti, G -- Tramacere, A -- Uchiyama, Y -- Usher, T L -- Van Etten, A -- Vasileiou, V -- Venter, C -- Vilchez, N -- Vitale, V -- Waite, A P -- Wallace, E -- Wang, P -- Watters, K -- Webb, N -- Weltevrede, P -- Winer, B L -- Wood, K S -- Ylinen, T -- Ziegler, M -- New York, N.Y. -- Science. 2009 Aug 14;325(5942):848-52. doi: 10.1126/science.1176113.〈br /〉〈span class="detail_caption"〉Author address: 〈/span〉Space Science Division, Naval Research Laboratory,Washington, DC 20375, USA.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/19574349" target="_blank"〉PubMed〈/a〉
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
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  • 5
    Publication Date: 2009-08-15
    Description: We report the detection of gamma-ray emissions above 200 megaelectron volts at a significance level of 17sigma from the globular cluster 47 Tucanae, using data obtained with the Large Area Telescope onboard the Fermi Gamma-ray Space Telescope. Globular clusters are expected to emit gamma rays because of the large populations of millisecond pulsars that they contain. The spectral shape of 47 Tucanae is consistent with gamma-ray emission from a population of millisecond pulsars. The observed gamma-ray luminosity implies an upper limit of 60 millisecond pulsars present in 47 Tucanae.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Abdo, A A -- Ackermann, M -- Ajello, M -- Atwood, W B -- Axelsson, M -- Baldini, L -- Ballet, J -- Barbiellini, G -- Bastieri, D -- Baughman, B M -- Bechtol, K -- Bellazzini, R -- Berenji, B -- Blandford, R D -- Bloom, E D -- Bonamente, E -- Borgland, A W -- Bregeon, J -- Brez, A -- Brigida, M -- Bruel, P -- Burnett, T H -- Caliandro, G A -- Cameron, R A -- Caraveo, P A -- Casandjian, J M -- Cecchi, C -- Celik, O -- Charles, E -- Chaty, S -- Chekhtman, A -- Cheung, C C -- Chiang, J -- Ciprini, S -- Claus, R -- Cohen-Tanugi, J -- Conrad, J -- Cutini, S -- Dermer, C D -- de Palma, F -- Digel, S W -- Dormody, M -- do Couto e Silva, E -- Drell, P S -- Dubois, R -- Dumora, D -- Farnier, C -- Favuzzi, C -- Fegan, S J -- Focke, W B -- Frailis, M -- Fukazawa, Y -- Fusco, P -- Gargano, F -- Gasparrini, D -- Gehrels, N -- Germani, S -- Giebels, B -- Giglietto, N -- Giordano, F -- Glanzman, T -- Godfrey, G -- Grenier, I A -- Grove, J E -- Guillemot, L -- Guiriec, S -- Hanabata, Y -- Harding, A K -- Hayashida, M -- Hays, E -- Horan, D -- Hughes, R E -- Johannesson, G -- Johnson, A S -- Johnson, R P -- Johnson, T J -- Johnson, W N -- Kamae, T -- Katagiri, H -- Kawai, N -- Kerr, M -- Knodlseder, J -- Kuehn, F -- Kuss, M -- Lande, J -- Latronico, L -- Lemoine-Goumard, M -- Longo, F -- Loparco, F -- Lott, B -- Lovellette, M N -- Lubrano, P -- Makeev, A -- Mazziotta, M N -- McConville, W -- McEnery, J E -- Meurer, C -- Michelson, P F -- Mitthumsiri, W -- Mizuno, T -- Moiseev, A A -- Monte, C -- Monzani, M E -- Morselli, A -- Moskalenko, I V -- Murgia, S -- Nolan, P L -- Norris, J P -- Nuss, E -- Ohsugi, T -- Omodei, N -- Orlando, E -- Ormes, J F -- Paneque, D -- Panetta, J H -- Parent, D -- Pelassa, V -- Pepe, M -- Pierbattista, M -- Piron, F -- Porter, T A -- Raino, S -- Rando, R -- Razzano, M -- Rea, N -- Reimer, A -- Reimer, O -- Reposeur, T -- Ritz, S -- Rochester, L S -- Rodriguez, A Y -- Romani, R W -- Roth, M -- Ryde, F -- Sadrozinski, H F-W -- Sanchez, D -- Sander, A -- Saz Parkinson, P M -- Sgro, C -- Smith, D A -- Smith, P D -- Spandre, G -- Spinelli, P -- Starck, J-L -- Strickman, M S -- Suson, D J -- Tajima, H -- Takahashi, H -- Tanaka, T -- Thayer, J B -- Thayer, J G -- Thompson, D J -- Tibaldo, L -- Torres, D F -- Tosti, G -- Tramacere, A -- Uchiyama, Y -- Usher, T L -- Vasileiou, V -- Vilchez, N -- Vitale, V -- Wang, P -- Webb, N -- Winer, B L -- Wood, K S -- Ylinen, T -- Ziegler, M -- New York, N.Y. -- Science. 2009 Aug 14;325(5942):845-8. doi: 10.1126/science.1177023.〈br /〉〈span class="detail_caption"〉Author address: 〈/span〉Space Science Division, Naval Research Laboratory, Washington, DC 20375, USA.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/19679807" target="_blank"〉PubMed〈/a〉
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  • 6
    Publication Date: 2009-02-21
    Description: Gamma-ray bursts (GRBs) are highly energetic explosions signaling the death of massive stars in distant galaxies. The Gamma-ray Burst Monitor and Large Area Telescope onboard the Fermi Observatory together record GRBs over a broad energy range spanning about 7 decades of gammaray energy. In September 2008, Fermi observed the exceptionally luminous GRB 080916C, with the largest apparent energy release yet measured. The high-energy gamma rays are observed to start later and persist longer than the lower energy photons. A simple spectral form fits the entire GRB spectrum, providing strong constraints on emission models. The known distance of the burst enables placing lower limits on the bulk Lorentz factor of the outflow and on the quantum gravity mass.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Fermi LAT and Fermi GBM Collaborations -- Abdo, A A -- Ackermann, M -- Arimoto, M -- Asano, K -- Atwood, W B -- Axelsson, M -- Baldini, L -- Ballet, J -- Band, D L -- Barbiellini, G -- Baring, M G -- Bastieri, D -- Battelino, M -- Baughman, B M -- Bechtol, K -- Bellardi, F -- Bellazzini, R -- Berenji, B -- Bhat, P N -- Bissaldi, E -- Blandford, R D -- Bloom, E D -- Bogaert, G -- Bogart, J R -- Bonamente, E -- Bonnell, J -- Borgland, A W -- Bouvier, A -- Bregeon, J -- Brez, A -- Briggs, M S -- Brigida, M -- Bruel, P -- Burnett, T H -- Burrows, D -- Busetto, G -- Caliandro, G A -- Cameron, R A -- Caraveo, P A -- Casandjian, J M -- Ceccanti, M -- Cecchi, C -- Celotti, A -- Charles, E -- Chekhtman, A -- Cheung, C C -- Chiang, J -- Ciprini, S -- Claus, R -- Cohen-Tanugi, J -- Cominsky, L R -- Connaughton, V -- Conrad, J -- Costamante, L -- Cutini, S -- Deklotz, M -- Dermer, C D -- de Angelis, A -- de Palma, F -- Digel, S W -- Dingus, B L -- do Couto E Silva, E -- Drell, P S -- Dubois, R -- Dumora, D -- Edmonds, Y -- Evans, P A -- Fabiani, D -- Farnier, C -- Favuzzi, C -- Finke, J -- Fishman, G -- Focke, W B -- Frailis, M -- Fukazawa, Y -- Funk, S -- Fusco, P -- Gargano, F -- Gasparrini, D -- Gehrels, N -- Germani, S -- Giebels, B -- Giglietto, N -- Giommi, P -- Giordano, F -- Glanzman, T -- Godfrey, G -- Goldstein, A -- Granot, J -- Greiner, J -- Grenier, I A -- Grondin, M-H -- Grove, J E -- Guillemot, L -- Guiriec, S -- Haller, G -- Hanabata, Y -- Harding, A K -- Hayashida, M -- Hays, E -- Hernando Morat, J A -- Hoover, A -- Hughes, R E -- Johannesson, G -- Johnson, A S -- Johnson, R P -- Johnson, T J -- Johnson, W N -- Kamae, T -- Katagiri, H -- Kataoka, J -- Kavelaars, A -- Kawai, N -- Kelly, H -- Kennea, J -- Kerr, M -- Kippen, R M -- Knodlseder, J -- Kocevski, D -- Kocian, M L -- Komin, N -- Kouveliotou, C -- Kuehn, F -- Kuss, M -- Lande, J -- Landriu, D -- Larsson, S -- Latronico, L -- Lavalley, C -- Lee, B -- Lee, S-H -- Lemoine-Goumard, M -- Lichti, G G -- Longo, F -- Loparco, F -- Lott, B -- Lovellette, M N -- Lubrano, P -- Madejski, G M -- Makeev, A -- Marangelli, B -- Mazziotta, M N -- McBreen, S -- McEnery, J E -- McGlynn, S -- Meegan, C -- Meszaros, P -- Meurer, C -- Michelson, P F -- Minuti, M -- Mirizzi, N -- Mitthumsiri, W -- Mizuno, T -- Moiseev, A A -- Monte, C -- Monzani, M E -- Moretti, E -- Morselli, A -- Moskalenko, I V -- Murgia, S -- Nakamori, T -- Nelson, D -- Nolan, P L -- Norris, J P -- Nuss, E -- Ohno, M -- Ohsugi, T -- Okumura, A -- Omodei, N -- Orlando, E -- Ormes, J F -- Ozaki, M -- Paciesas, W S -- Paneque, D -- Panetta, J H -- Parent, D -- Pelassa, V -- Pepe, M -- Perri, M -- Pesce-Rollins, M -- Petrosian, V -- Pinchera, M -- Piron, F -- Porter, T A -- Preece, R -- Raino, S -- Ramirez-Ruiz, E -- Rando, R -- Rapposelli, E -- Razzano, M -- Razzaque, S -- Rea, N -- Reimer, A -- Reimer, O -- Reposeur, T -- Reyes, L C -- Ritz, S -- Rochester, L S -- Rodriguez, A Y -- Roth, M -- Ryde, F -- Sadrozinski, H F-W -- Sanchez, D -- Sander, A -- Saz Parkinson, P M -- Scargle, J D -- Schalk, T L -- Segal, K N -- Sgro, C -- Shimokawabe, T -- Siskind, E J -- Smith, D A -- Smith, P D -- Spandre, G -- Spinelli, P -- Stamatikos, M -- Starck, J-L -- Stecker, F W -- Steinle, H -- Stephens, T E -- Strickman, M S -- Suson, D J -- Tagliaferri, G -- Tajima, H -- Takahashi, H -- Takahashi, T -- Tanaka, T -- Tenze, A -- Thayer, J B -- Thayer, J G -- Thompson, D J -- Tibaldo, L -- Torres, D F -- Tosti, G -- Tramacere, A -- Turri, M -- Tuvi, S -- Usher, T L -- van der Horst, A J -- Vigiani, L -- Vilchez, N -- Vitale, V -- von Kienlin, A -- Waite, A P -- Williams, D A -- Wilson-Hodge, C -- Winer, B L -- Wood, K S -- Wu, X F -- Yamazaki, R -- Ylinen, T -- Ziegler, M -- New York, N.Y. -- Science. 2009 Mar 27;323(5922):1688-93. doi: 10.1126/science.1169101. Epub 2009 Feb 19.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/19228997" target="_blank"〉PubMed〈/a〉
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
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  • 7
    Publication Date: 2009-12-08
    Description: Microquasars are accreting black holes or neutron stars in binary systems with associated relativistic jets. Despite their frequent outburst activity, they have never been unambiguously detected emitting high-energy gamma rays. The Fermi Large Area Telescope (LAT) has detected a variable high-energy source coinciding with the position of the x-ray binary and microquasar Cygnus X-3. Its identification with Cygnus X-3 is secured by the detection of its orbital period in gamma rays, as well as the correlation of the LAT flux with radio emission from the relativistic jets of Cygnus X-3. The gamma-ray emission probably originates from within the binary system, opening new areas in which to study the formation of relativistic jets.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Fermi LAT Collaboration -- Abdo, A A -- Ackermann, M -- Ajello, M -- Axelsson, M -- Baldini, L -- Ballet, J -- Barbiellini, G -- Bastieri, D -- Baughman, B M -- Bechtol, K -- Bellazzini, R -- Berenji, B -- Blandford, R D -- Bloom, E D -- Bonamente, E -- Borgland, A W -- Brez, A -- Brigida, M -- Bruel, P -- Burnett, T H -- Buson, S -- Caliandro, G A -- Cameron, R A -- Caraveo, P A -- Casandjian, J M -- Cecchi, C -- Celik, O -- Chaty, S -- Cheung, C C -- Chiang, J -- Ciprini, S -- Claus, R -- Cohen-Tanugi, J -- Cominsky, L R -- Conrad, J -- Corbel, S -- Corbet, R -- Dermer, C D -- de Palma, F -- Digel, S W -- do Couto e Silva, E -- Drell, P S -- Dubois, R -- Dubus, G -- Dumora, D -- Farnier, C -- Favuzzi, C -- Fegan, S J -- Focke, W B -- Fortin, P -- Frailis, M -- Fusco, P -- Gargano, F -- Gehrels, N -- Germani, S -- Giavitto, G -- Giebels, B -- Giglietto, N -- Giordano, F -- Glanzman, T -- Godfrey, G -- Grenier, I A -- Grondin, M-H -- Grove, J E -- Guillemot, L -- Guiriec, S -- Hanabata, Y -- Harding, A K -- Hayashida, M -- Hays, E -- Hill, A B -- Hjalmarsdotter, L -- Horan, D -- Hughes, R E -- Jackson, M S -- Johannesson, G -- Johnson, A S -- Johnson, T J -- Johnson, W N -- Kamae, T -- Katagiri, H -- Kawai, N -- Kerr, M -- Knodlseder, J -- Kocian, M L -- Koerding, E -- Kuss, M -- Lande, J -- Latronico, L -- Lemoine-Goumard, M -- Longo, F -- Loparco, F -- Lott, B -- Lovellette, M N -- Lubrano, P -- Madejski, G M -- Makeev, A -- Marchand, L -- Marelli, M -- Max-Moerbeck, W -- Mazziotta, M N -- McColl, N -- McEnery, J E -- Meurer, C -- Michelson, P F -- Migliari, S -- Mitthumsiri, W -- Mizuno, T -- Monte, C -- Monzani, M E -- Morselli, A -- Moskalenko, I V -- Murgia, S -- Nolan, P L -- Norris, J P -- Nuss, E -- Ohsugi, T -- Omodei, N -- Ong, R A -- Ormes, J F -- Paneque, D -- Parent, D -- Pelassa, V -- Pepe, M -- Pesce-Rollins, M -- Piron, F -- Pooley, G -- Porter, T A -- Pottschmidt, K -- Raino, S -- Rando, R -- Ray, P S -- Razzano, M -- Rea, N -- Readhead, A -- Reimer, A -- Reimer, O -- Richards, J L -- Rochester, L S -- Rodriguez, J -- Rodriguez, A Y -- Romani, R W -- Ryde, F -- Sadrozinski, H F-W -- Sander, A -- Saz Parkinson, P M -- Sgro, C -- Siskind, E J -- Smith, D A -- Smith, P D -- Spinelli, P -- Starck, J-L -- Stevenson, M -- Strickman, M S -- Suson, D J -- Takahashi, H -- Tanaka, T -- Thayer, J B -- Thompson, D J -- Tibaldo, L -- Tomsick, J A -- Torres, D F -- Tosti, G -- Tramacere, A -- Uchiyama, Y -- Usher, T L -- Vasileiou, V -- Vilchez, N -- Vitale, V -- Waite, A P -- Wang, P -- Wilms, J -- Winer, B L -- Wood, K S -- Ylinen, T -- Ziegler, M -- New York, N.Y. -- Science. 2009 Dec 11;326(5959):1512-6. doi: 10.1126/science.1182174. Epub .〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/19965378" target="_blank"〉PubMed〈/a〉
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
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  • 8
    Publication Date: 2009-11-29
    Print ISSN: 0959-6658
    Electronic ISSN: 1460-2423
    Topics: Biology , Medicine
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