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  • 1
    Electronic Resource
    Electronic Resource
    We have a morphogen! (1987)
    [s.l.] : Nature Publishing Group
    Nature 327 (1987), S. 553-554 
    Details
    ISSN: 1476-4687
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Chemistry and Pharmacology , Medicine , Natural Sciences in General , Physics
    Notes: [Auszug] THE first moiphogen has been identified and it is reiinoic acid. Of course nothing in science is really certain, so perhaps I should say that the article by Thaller and Eichele on page 625 of this issue1 com-pletes a strong prima fade case for the identity of the first moiphogen. So what is a ...
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1038/327553a0
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  • 2
    Electronic Resource
    Electronic Resource
    Out on a limb (1991)
    [s.l.] : Nature Publishing Group
    Nature 354 (1991), S. 26-26 
    Details
    ISSN: 1476-4687
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Chemistry and Pharmacology , Medicine , Natural Sciences in General , Physics
    Notes: [Auszug] SLACK REPLIES - How can we know whether a molecule is really acting as a morphogen? Like many others I have spent some time thinking about this and have published a set of possible criteria . To simplify these somewhat: the substance should have the expected biological activity; ...
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1038/354026b0
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  • 3
    Electronic Resource
    Electronic Resource
    The inducer that never was (1994)
    [s.l.] : Nature Publishing Group
    Nature 369 (1994), S. 279-280 
    Details
    ISSN: 1476-4687
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Chemistry and Pharmacology , Medicine , Natural Sciences in General , Physics
    Notes: [Auszug] KING Lear may have said "Nothing will come of nothing". But had his daughter Cordelia been a developmental biologist she might have inherited the anterior third of the nervous system, and her more obsequious sisters been left with the trunk and tail. This surprising outcome is suggested by work on ...
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1038/369279a0
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  • 4
    Electronic Resource
    Electronic Resource
    How to make the gradient (1994)
    [s.l.] : Nature Publishing Group
    Nature 371 (1994), S. 477-478 
    Details
    ISSN: 1476-4687
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Chemistry and Pharmacology , Medicine , Natural Sciences in General , Physics
    Notes: [Auszug] ON page 487 of this issue1, John Gurdon and colleagues describe how they have taken a fresh look at how morphogenetic gradients work in the early stages of animal development. The gradient is an idea of long standing. It goes back to the experiments of Child in the early years of the present ...
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1038/371477a0
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  • 5
    Electronic Resource
    Electronic Resource
    The zootype and the phylotypic stage (1993)
    [s.l.] : Nature Publishing Group
    Nature 361 (1993), S. 490-492 
    Details
    ISSN: 1476-4687
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Chemistry and Pharmacology , Medicine , Natural Sciences in General , Physics
    Notes: [Auszug] WHAT is an animal? According to elementary textbooks of biology it is an organism that feeds, moves and responds to stimuli. But this definition is purely behavioural. Since the time of Geoffroy St Hilaire, there has been no morpho-logical concept of what an animal really is. We propose that an ...
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1038/361490a0
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  • 6
    Electronic Resource
    Electronic Resource
    Noggin the dorsalizer (1993)
    [s.l.] : Nature Publishing Group
    Nature 361 (1993), S. 498-499 
    Details
    ISSN: 1476-4687
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Chemistry and Pharmacology , Medicine , Natural Sciences in General , Physics
    Notes: [Auszug] OUTSIDERS must be puzzled by the fact that so many papers on Xenopus devel-opment open with a reference to the classical organizer graft1, which produces a double embryo following transplanta-tion of a dorsal lip into a host gastrula. Surely this problem must have been solved by now? How can the ...
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1038/361498a0
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  • 7
    Electronic Resource
    Electronic Resource
    Growth factor lends a hand (1995)
    [s.l.] : Nature Publishing Group
    Nature 374 (1995), S. 217-218 
    Details
    ISSN: 1476-4687
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Chemistry and Pharmacology , Medicine , Natural Sciences in General , Physics
    Notes: [Auszug] IN a remarkable series of experiments over 60 years ago, Balinsky was able to induce complete extra limbs by implan-tation of nasal tissue into the flank of amphibian embryos1 (see figure). These results have since reposed in the shadowy world of half-forgotten things, both be-cause they were ...
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1038/374217a0
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  • 8
    Electronic Resource
    Electronic Resource
    High hops of transgenic frogs (1996)
    [s.l.] : Nature Publishing Group
    Nature 383 (1996), S. 765-766 
    Details
    ISSN: 1476-4687
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Chemistry and Pharmacology , Medicine , Natural Sciences in General , Physics
    Notes: [Auszug] THOSE of us who work in developmental biology, and use the frog Xenopus laevis as our experimental organism, are used to being stopped in the corridor and told that Xenopus are useless because "They have no genetics". Other model organisms such as Drosophila, mouse, zebrafish and Caenorhabditis ...
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1038/383765a0
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  • 9
    Electronic Resource
    Electronic Resource
    Determination and cellular commitment in the embryonic amphibian mesoderm (1980)
    [s.l.] : Nature Publishing Group
    Nature 286 (1980), S. 492-494 
    Details
    ISSN: 1476-4687
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Chemistry and Pharmacology , Medicine , Natural Sciences in General , Physics
    Notes: [Auszug] In the experiments described here, the prospective somite region of the axolotl (Ambystoma mexicanum) was treated in one of four different ways as shown in Fig. 1. (1) The region was dissected out, wrapped in an ectodermal jacket obtained from the anteroventral region of a stage 13 embryo, and ...
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1038/286492a0
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  • 10
    Electronic Resource
    Electronic Resource
    Regeneration of reduplicated limbs in contravention of the complete circle rule (1978)
    [s.l.] : Nature Publishing Group
    Nature 271 (1978), S. 760-761 
    Details
    ISSN: 1476-4687
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Chemistry and Pharmacology , Medicine , Natural Sciences in General , Physics
    Notes: [Auszug] The model comprises two basic rules which determine whether a particular part of an organ will regenerate and which structures will be formed if it does so. The first rule is that of 'shortest intercalation' and states that when tissues of different positional values are brought together then the ...
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1038/271760a0
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