ISSN:
1573-0832
Source:
Springer Online Journal Archives 1860-2000
Topics:
Biology
,
Medicine
Notes:
Abstract Three strains ofCandida albicans, isolated from burn patients who succumbed to systemic candidiasis, were studied in random-bred Swiss white mice to determine their relative pathogenicity and their histopathology. The most virulent strain caused 89.5 % mortality, compared to 70 % and 65 % at 21 days for the other two strains. Histopathological studies showed extensive involvement of the kidneys, with heavy colonization of the renal pelvis; pseudomycelia, budding cells, and blastospores were observed in all animals that died. Animals surviving after 21 days were sacrificed; no extreme pathological reaction nor cells ofC. albicans could be detected.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1007/BF02050722
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