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Parasitism of monolayer cultures of dog tissue by Histoplasma capsulatum, I preliminary investigations

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Summary

Monolayer tissue cultures of canine kidney are demonstrated to by susceptible to invasion by yeast-phaseHistoplasma capsulatum. Primary and secondary tissue cultures of canine kidney show different levels of invasion by the pathogen at 24 hours after inoculation; these differences are interpreted as being related to the number of dividing host cells. By 72 hours after inoculation, similar numbers of yeast cells are demonstrable within the host cells of primary and secondary cultures. Essentially identical results were obtained when canine heart tissue cultures were inoculated with y-phaseH. capsulatum.

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Author notes

  1. Aliza Adler M. S. (Research Assistant)

    Present address: Israel Institute for Biological Research, P.O.B. 19, Ness-Ziona, Israel

Authors and Affiliations

  1. Department of Botany and Plant Pathology, USA

    J. A. Schmitt Ph. D. (Associate Professor)

Authors
  1. Aliza Adler M. S.
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  2. J. A. Schmitt Ph. D.
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Additional information

Paper No.713, Department of Botany and Plant Pathology, The Ohio State University, 1735 Neil Avenue, Columbus 10, Ohio; correspondence should be directed to the junior author at the above address.

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Adler, A., Schmitt, J.A. Parasitism of monolayer cultures of dog tissue by Histoplasma capsulatum, I preliminary investigations. Mycopathologia et Mycologia Applicata 30, 72–78 (1966). https://doi.org/10.1007/BF02051711

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