Publication Date:
2002-11-26
Description:
The origin of the domestic dog from wolves has been established, but the number of founding events, as well as where and when these occurred, is not known. To address these questions, we examined the mitochondrial DNA (mtDNA) sequence variation among 654 domestic dogs representing all major dog populations worldwide. Although our data indicate several maternal origins from wolf, 〉95% of all sequences belonged to three phylogenetic groups universally represented at similar frequencies, suggesting a common origin from a single gene pool for all dog populations. A larger genetic variation in East Asia than in other regions and the pattern of phylogeographic variation suggest an East Asian origin for the domestic dog, approximately 15,000 years ago.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Savolainen, Peter -- Zhang, Ya-ping -- Luo, Jing -- Lundeberg, Joakim -- Leitner, Thomas -- New York, N.Y. -- Science. 2002 Nov 22;298(5598):1610-3.〈br /〉〈span class="detail_caption"〉Author address: 〈/span〉Department of Biotechnology, Royal Institute of Technology (KTH), 10691 Stockholm, Sweden. savo@biotech.kth.se〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/12446907" target="_blank"〉PubMed〈/a〉
Keywords:
Animals
;
Animals, Domestic/anatomy & histology/classification/*genetics
;
Archaeology
;
Asia
;
DNA, Mitochondrial/*genetics
;
Dogs/anatomy & histology/classification/*genetics
;
Female
;
Gene Pool
;
Genes
;
*Genetic Variation
;
Haplotypes
;
Molecular Sequence Data
;
Phylogeny
;
Time
;
Wolves/genetics
Print ISSN:
0036-8075
Electronic ISSN:
1095-9203
Topics:
Biology
,
Chemistry and Pharmacology
,
Computer Science
,
Medicine
,
Natural Sciences in General
,
Physics
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