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  • 1
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    Parameter Estimation of a Delay Time Model of Wearing Parts Based on Objective Data (2015)
    Hindawi
    Details
    Publication Date: 2015-07-13
    Description: The wearing parts of a system have a very high failure frequency, making it necessary to carry out continual functional inspections and maintenance to protect the system from unscheduled downtime. This allows for the collection of a large amount of maintenance data. Taking the unique characteristics of the wearing parts into consideration, we establish their respective delay time models in ideal inspection cases and nonideal inspection cases. The model parameters are estimated entirely using the collected maintenance data. Then, a likelihood function of all renewal events is derived based on their occurring probability functions, and the model parameters are calculated with the maximum likelihood function method, which is solved by the CRM. Finally, using two wearing parts from the oil and gas drilling industry as examples—the filter element and the blowout preventer rubber core—the parameters of the distribution function of the initial failure time and the delay time for each example are estimated, and their distribution functions are obtained. Such parameter estimation based on objective data will contribute to the optimization of the reasonable function inspection interval and will also provide some theoretical models to support the integrity management of equipment or systems.
    Print ISSN: 1024-123X
    Electronic ISSN: 1563-5147
    Topics: Mathematics , Technology
    Published by Hindawi
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  • 2
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    Whole-genome shotgun optical mapping of Deinococcus radiodurans (1999)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1999-09-08
    Description: A whole-genome restriction map of Deinococcus radiodurans, a radiation-resistant bacterium able to survive up to 15,000 grays of ionizing radiation, was constructed without using DNA libraries, the polymerase chain reaction, or electrophoresis. Very large, randomly sheared, genomic DNA fragments were used to construct maps from individual DNA molecules that were assembled into two circular overlapping maps (2.6 and 0.415 megabases), without gaps. A third smaller chromosome (176 kilobases) was identified and characterized. Aberrant nonlinear DNA structures that may define chromosome structure and organization, as well as intermediates in DNA repair, were directly visualized by optical mapping techniques after gamma irradiation.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Lin, J -- Qi, R -- Aston, C -- Jing, J -- Anantharaman, T S -- Mishra, B -- White, O -- Daly, M J -- Minton, K W -- Venter, J C -- Schwartz, D C -- GM 39933/GM/NIGMS NIH HHS/ -- HG0025-08/HG/NHGRI NIH HHS/ -- New York, N.Y. -- Science. 1999 Sep 3;285(5433):1558-62.〈br /〉〈span class="detail_caption"〉Author address: 〈/span〉W. M. Keck Laboratory for Biomolecular Imaging, Department of Chemistry, New York University, 31 Washington Place, New York, NY 10003, USA.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/10477518" target="_blank"〉PubMed〈/a〉
    Keywords: Chromosomes, Bacterial ; Contig Mapping/*methods ; DNA Damage ; DNA Repair ; DNA, Bacterial/chemistry/genetics/radiation effects ; DNA, Circular/chemistry ; Gamma Rays ; *Genome, Bacterial ; Gram-Positive Cocci/*genetics/radiation effects ; Image Processing, Computer-Assisted ; Microscopy, Fluorescence ; Nucleic Acid Conformation ; Plasmids ; Radiation Tolerance ; Recombination, Genetic ; Restriction Mapping/*methods
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
    Published by American Association for the Advancement of Science (AAAS)
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  • 3
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    Chromosome 2 sequence of the human malaria parasite Plasmodium falciparum (1998)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1998-11-06
    Description: Chromosome 2 of Plasmodium falciparum was sequenced; this sequence contains 947,103 base pairs and encodes 210 predicted genes. In comparison with the Saccharomyces cerevisiae genome, chromosome 2 has a lower gene density, introns are more frequent, and proteins are markedly enriched in nonglobular domains. A family of surface proteins, rifins, that may play a role in antigenic variation was identified. The complete sequencing of chromosome 2 has shown that sequencing of the A+T-rich P. falciparum genome is technically feasible.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Gardner, M J -- Tettelin, H -- Carucci, D J -- Cummings, L M -- Aravind, L -- Koonin, E V -- Shallom, S -- Mason, T -- Yu, K -- Fujii, C -- Pederson, J -- Shen, K -- Jing, J -- Aston, C -- Lai, Z -- Schwartz, D C -- Pertea, M -- Salzberg, S -- Zhou, L -- Sutton, G G -- Clayton, R -- White, O -- Smith, H O -- Fraser, C M -- Adams, M D -- Venter, J C -- Hoffman, S L -- R01 AI40125-01/AI/NIAID NIH HHS/ -- New York, N.Y. -- Science. 1998 Nov 6;282(5391):1126-32.〈br /〉〈span class="detail_caption"〉Author address: 〈/span〉Institute for Genomic Research, Rockville, MD 20850, USA.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/9804551" target="_blank"〉PubMed〈/a〉
    Keywords: Amino Acid Sequence ; Animals ; Antigens, Protozoan/chemistry/genetics ; Base Composition ; Chromosomes/*genetics ; Evolution, Molecular ; *Genes, Protozoan ; Genome, Protozoan ; Introns ; Membrane Proteins/chemistry/genetics ; Molecular Sequence Data ; Multigene Family ; Physical Chromosome Mapping ; Plasmodium falciparum/*genetics ; Protozoan Proteins/chemistry/*genetics ; RNA, Protozoan/genetics ; RNA, Transfer, Glu/genetics ; Repetitive Sequences, Nucleic Acid ; Reverse Transcriptase Polymerase Chain Reaction ; Sequence Alignment ; *Sequence Analysis, DNA
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
    Published by American Association for the Advancement of Science (AAAS)
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  • 4
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    China and AIDS--the time to act is now (2002)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 2002-06-29
    Description: 〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Kaufman, Joan -- Jing, Jun -- New York, N.Y. -- Science. 2002 Jun 28;296(5577):2339-40.〈br /〉〈span class="detail_caption"〉Author address: 〈/span〉Radcliffe Institute for Advanced Studies, Harvard University, Cambridge, MA 02138, USA. joankaufman@levineonline.com〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/12089428" target="_blank"〉PubMed〈/a〉
    Keywords: *Acquired Immunodeficiency Syndrome/drug therapy/epidemiology/prevention & ; control/transmission ; Anti-HIV Agents/supply & distribution/therapeutic use ; Blood Donors ; China/epidemiology ; *Disease Outbreaks ; Female ; Government Programs ; *HIV Infections/drug therapy/epidemiology/prevention & control/transmission ; Health Education ; Health Expenditures ; Health Personnel/education ; Health Policy ; Health Services ; Homosexuality, Male ; Humans ; Incidence ; Male ; Prevalence ; Prostitution ; Substance Abuse, Intravenous/complications
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
    Published by American Association for the Advancement of Science (AAAS)
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  • 5
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    Chemoenzymatic synthesis of homogeneous ultralow molecular weight heparins (2011)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 2011-10-29
    Description: Ultralow molecular weight (ULMW) heparins are sulfated glycans that are clinically used to treat thrombotic disorders. ULMW heparins range from 1500 to 3000 daltons, corresponding from 5 to 10 saccharide units. The commercial drug Arixtra (fondaparinux sodium) is a structurally homogeneous ULMW heparin pentasaccharide that is synthesized through a lengthy chemical process. Here, we report 10- and 12-step chemoenzymatic syntheses of two structurally homogeneous ULMW heparins (MW = 1778.5 and 1816.5) in 45 and 37% overall yield, respectively, starting from a simple disaccharide. These ULMW heparins display excellent in vitro anticoagulant activity and comparable pharmacokinetic properties to Arixtra, as demonstrated in a rabbit model. The chemoenzymatic approach is scalable and shows promise for a more efficient route to synthesize this important class of medicinal agent.〈br /〉〈br /〉〈a href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3425363/" target="_blank"〉〈img src="https://static.pubmed.gov/portal/portal3rc.fcgi/4089621/img/3977009" border="0"〉〈/a〉   〈a href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3425363/" target="_blank"〉This paper as free author manuscript - peer-reviewed and accepted for publication〈/a〉〈br /〉〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Xu, Yongmei -- Masuko, Sayaka -- Takieddin, Majde -- Xu, Haoming -- Liu, Renpeng -- Jing, Juliana -- Mousa, Shaker A -- Linhardt, Robert J -- Liu, Jian -- AI074775/AI/NIAID NIH HHS/ -- AI50050/AI/NIAID NIH HHS/ -- GM38060/GM/NIGMS NIH HHS/ -- HL094463/HL/NHLBI NIH HHS/ -- HL096972/HL/NHLBI NIH HHS/ -- HL62244/HL/NHLBI NIH HHS/ -- R01 AI050050/AI/NIAID NIH HHS/ -- R01 GM038060/GM/NIGMS NIH HHS/ -- R01 HL062244/HL/NHLBI NIH HHS/ -- R01 HL094463/HL/NHLBI NIH HHS/ -- R01 HL096972/HL/NHLBI NIH HHS/ -- R21 AI074775/AI/NIAID NIH HHS/ -- New York, N.Y. -- Science. 2011 Oct 28;334(6055):498-501. doi: 10.1126/science.1207478.〈br /〉〈span class="detail_caption"〉Author address: 〈/span〉Division of Medicinal Chemistry and Natural Products, Eshelman School of Pharmacy, University of North Carolina, Chapel Hill, NC 27599, USA.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/22034431" target="_blank"〉PubMed〈/a〉
    Keywords: Animals ; Anticoagulants/*chemical synthesis/chemistry/pharmacokinetics/pharmacology ; Antithrombins/chemistry/metabolism ; Binding Sites ; Chemical Processes ; Glycosyltransferases/metabolism ; Heparin, Low-Molecular-Weight/*chemical ; synthesis/chemistry/pharmacokinetics/pharmacology ; Molecular Structure ; Molecular Weight ; N-Acetylglucosaminyltransferases/metabolism ; Oligosaccharides/chemistry ; Polysaccharides/chemistry/pharmacokinetics/pharmacology ; Rabbits ; Racemases and Epimerases/metabolism ; Spectrometry, Mass, Electrospray Ionization ; Substrate Specificity ; Sulfotransferases/metabolism
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
    Published by American Association for the Advancement of Science (AAAS)
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  • 6
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    Sussing Merger Trees: The Merger Trees Comparison Project (2013)
    Oxford University Press
    Details
    Publication Date: 2013-10-29
    Description: Merger trees follow the growth and merger of dark-matter haloes over cosmic history. As well as giving important insights into the growth of cosmic structure in their own right, they provide an essential backbone to semi-analytic models of galaxy formation. This paper is the first in a series to arise from the Sussing Merger Trees Workshop in which 10 different tree-building algorithms were applied to the same set of halo catalogues and their results compared. Although many of these codes were similar in nature, all algorithms produced distinct results. Our main conclusions are that a useful merger-tree code should possess the following features: (i) the use of particle IDs to match haloes between snapshots; (ii) the ability to skip at least one, and preferably more, snapshots in order to recover subhaloes that are temporarily lost during merging; (iii) the ability to cope with (and ideally smooth out) large, temporary fluctuations in halo mass. Finally, to enable different groups to communicate effectively, we defined a common terminology that we used when discussing merger trees and we encourage others to adopt the same language. We also specified a minimal output format to record the results.
    Print ISSN: 0035-8711
    Electronic ISSN: 1365-2966
    Topics: Physics
    Published by Oxford University Press
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  • 7
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    The Effect of Solids Inventory and Other Factors on the Axial Solids Holdup Profiles in a Twin-Riser System (2004)
    Wiley
    Details
    Publication Date: 2004-04-01
    Print ISSN: 0930-7516
    Electronic ISSN: 1521-4125
    Topics: Chemistry and Pharmacology , Process Engineering, Biotechnology, Nutrition Technology
    Published by Wiley
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  • 8
    Electronic Resource
    Electronic Resource
    Suppression of superparamagnetism in surface-oxidized nanocrystals (1990)
    Springer
    Il nuovo cimento della Società Italiana di Fisica 12 (1990), S. 35-43 
    Details
    ISSN: 0392-6737
    Keywords: Diamagnetism and paramagnetism
    Source: Springer Online Journal Archives 1860-2000
    Topics: Physics
    Description / Table of Contents: Riassunto Si sono preparati nanocristalli di Fe (particelle con una dimensione di alcuni nanometri) per mezzo del metodo della condensazione di gas inerti con conseguente ossidazione. La misura media delle particelle nel fine strato di ossido è stata determinata intorno ai 30 Å. Si sono studiati i campioni attraverso la spettroscopia di Mössbauer a varie temperature. In questi esempi il supermagnetismo sembra essere soppresso. Inoltre si è osservata una diminuzione del campo medio iperfino nello strato di ossido. L'anisotropia dell'interfaccia tra ossido di Fe e Fe è proposta come causa di questo fenomeno.
    Abstract: Резюме Используя метод конденсации в инертном газе с последующим окислением, приготовляутся нанокристаллы железа (частицы с размерами порядка нанометров). Средние размеры частиц в тонком слое окисла составляют около 30 Å. Полученные образцы исследуются с помощью Мессбаузровской спектроскопии при различных температурах. Наблюдается двух-ступенчатое уменьшение среднего сверхтонного поля в слоях окисла. Предполагается, что анизотропия границы раздела между окислом железа и железом является ответственной за это явление.
    Notes: Summary Fe nanocrystals (particles with a size of some nanometers) were prepared by the inert-gas condensation method with subsequent oxidization. The average size of the particles in the thin oxide layer was determined to be about 30 Å. The samples were studied by Mössbauer spectroscopy at various temperatures. Superparamagnetism seems to be suppressed in these samples. Furthermore, a two-stage decrease of the average hyperfine field was observed in the oxide layer. The Fe oxide-Fe interface anisotropy is proposed to be responsible for this phenomenon.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF02453024
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  • 9
    Electronic Resource
    Electronic Resource
    Structure and superconducting properties of YBa"2(Cu"1"-"x Fe"x)"3O"7
    Amsterdam : Elsevier
    Physica C: Superconductivity and its applications 153-155 (1988), S. 952-953 
    Details
    ISSN: 0921-4534
    Source: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
    Topics: Physics
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1016/S0921-4534(88)80171-0
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  • 10
    Electronic Resource
    Electronic Resource
    Thermodynamics of a black hole with a global monopole
    Amsterdam : Elsevier
    Physics Letters A 178 (1993), S. 59-61 
    Details
    ISSN: 0375-9601
    Source: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
    Topics: Physics
    Type of Medium: Electronic Resource
    URL: http://linkinghub.elsevier.com/retrieve/pii/0375-9601(93)90728-I
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