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  • 1
    Electronic Resource
    Electronic Resource
    Über eine frühe Beobachtung solarer Höhenstrahlung (1964)
    Springer
    Naturwissenschaften 51 (1964), S. 34-34 
    Details
    ISSN: 1432-1904
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Chemistry and Pharmacology , Natural Sciences in General
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00622575
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  • 2
    Electronic Resource
    Electronic Resource
    Effect of conditioned media on nerve cell differentiation (1980)
    Springer
    Cellular and molecular life sciences 36 (1980), S. 660-662 
    Details
    ISSN: 1420-9071
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Notes: Summary Glial conditioned medium strongly stimulates the morphological maturation of cultured neuronal cells, while fibroblast and meningeal conditioned media have weaker effects.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01970123
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  • 3
    Electronic Resource
    Electronic Resource
    Co2+ and Mn2+ ion locations in doped CsCdCl3 (1983)
    Springer
    Il nuovo cimento della Società Italiana di Fisica 2 (1983), S. 1964-1970 
    Details
    ISSN: 0392-6737
    Keywords: Electron paramagnetic resonance and relaxation
    Source: Springer Online Journal Archives 1860-2000
    Topics: Physics
    Description / Table of Contents: Riassunto Gli ioni di sostituzione Co2+ e Mn2+ in due diverse posizioni nel Cd nel composto CsCdCl3 sono state studiati usando la risonanza paramagnetica elettronica. L'occupazione preferenziale, Co2+ nel sito CdII, Mn2+ nel sito CdI, è discussa in termini di argomenti di simmetria della chimica dei cristalli.
    Abstract: Резюме Используя электронный парамагнитный резонанс, в соединении CsCdCl3 исследуются местоположения ионов замещения Co2+ и Mn2+ в двух различных положениях Cd. В терминах кристалло-химической симметрии обсуждается предпочтительное расположение Co2+ в положении CdII и Mn2+ в положении CdI.
    Notes: Summary Substitutional Co2+ and Mn2+ ions at the two different Cd sites in the compound CsCdCl3 have been studied by using electron paramagnetic resonance. The preferential occupation, Co2+ in the CdII site, Mn2+ in the CdI site, is discussed in terms of crystallochemical symmetry arguments.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF02457895
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  • 4
    Electronic Resource
    Electronic Resource
    Cell-Free translation of Balbiani ring RNA (75S) ofChironomus tentans salivary glands into high molecular weight products (1983)
    Springer
    Development genes and evolution 192 (1983), S. 200-203 
    Details
    ISSN: 1432-041X
    Keywords: Balbiani ring ; Cell-free translation ; Chironomus messenger RNA ; Secretory proteins
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology
    Notes: Summary Cell-free translation of salivary gland RNA or of purified Balbiani ring RNA (75S) in a reticulocyte lysate system gives rise to high molecular weight translational products (HMTP). In addition to a common size (approx. 1×106 daltons) HMTP share imunogenic determinants with the giant secretory proteins of salivary glands. This suggests that HMTP correspond to in vivo secreted proteins and thus, corroborates the notion that 75S-RNA is the messenger for these proteins. The time course of HMTP synthesis and the lack of appearance of lower molecular weight components as translational products of 75S-RNA indicate that the synthesis of HMTP (and of secretory proteins) occurs in one piece by an uninterrupted process. HMTP are regarded the largest polypeptides so far synthesized in a cell-free system.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00848691
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  • 5
    Electronic Resource
    Electronic Resource
    Anion and cation vacancies in CdTe (1995)
    Springer
    Applied physics 61 (1995), S. 213-215 
    Details
    ISSN: 1432-0630
    Keywords: 76.70.Dx ; 71.55.Gs
    Source: Springer Online Journal Archives 1860-2000
    Topics: Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics , Physics
    Notes: Abstract The cadmium vacancy (VCd) and the tellurium vacancy (VTe) in CdTe are identified by Electron Paramagnetic Resonance (EPR). The EPR spectrum of the singly ionised VTe reveals cubic (unpertubed) symmetry and the hyperfine structure shows that the unpaired electron is equally spread over the four Cd neighbors. Further figand hyperfine interactions with the more distant neighbors are resolved by Electron Nuclear Double Resonance (ENDOR). The VCd is a double acceptor and the EPR spectrum is observed in its singly negative charge state. The symmerty is found to be trigonal, which can be explained in a model in which the hole occupies a dangling bondt 2 orbital and the orbital degeneracy is removed by a static Jahn-Teller distortion. The hyperfine interaction shows that the hole is localised on one of the four Te neighbors.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01538392
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  • 6
    Electronic Resource
    Electronic Resource
    Anion and cation vacancies in CdTe (1995)
    Springer
    Applied physics 61 (1995), S. 213-215 
    Details
    ISSN: 1432-0630
    Keywords: PACS: 76.70.Dx; 71.55.Gs
    Source: Springer Online Journal Archives 1860-2000
    Topics: Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics , Physics
    Notes: Abstract.  The cadmium vacancy (VCd) and the tellurium vacancy (VTe) in CdTe are identified by Electron Paramagnetic Resonance (EPR). The EPR spectrum of the singly ionised VTe reveals cubic (unpertubed) symmetry and the hyperfine structure shows that the unpaired electron is equally spread over the four Cd neighbors. Further ligand hyperfine interactions with the more distant neighbors are resolved by Electron Nuclear Double Resonance (ENDOR). The VCd is a double acceptor and the EPR spectrum is observed in its singly negative charge state. The symmerty is found to be trigonal, which can be explained in a model in which the hole occupies a dangling bond t 2 orbital and the orbital degeneracy is removed by a static Jahn–Teller distortion. The hyperfine interaction shows that the hole is localised on one of the four Te neighbors.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/s003390050193
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  • 7
    Electronic Resource
    Electronic Resource
    Pharmacokinetic aspects of the interaction between clobazam and cimetidine (1983)
    Springer
    European journal of clinical pharmacology 25 (1983), S. 139-142 
    Details
    ISSN: 1432-1041
    Keywords: clobazam ; cimetidine ; N-desmethylclobazam ; kinetic interaction ; man
    Source: Springer Online Journal Archives 1860-2000
    Topics: Chemistry and Pharmacology , Medicine
    Notes: Summary The pharmacokinetic interaction between clobazam and cimetidine was studied in 9 healthy male volunteers in an open-labelled study. After a single oral dose of clobazam 30 mg, a wash-out period of 14 days was followed by daily doses of cimetidine 1 g for one week. Thereafter a single oral dose of clobazam 30 mg was again given. The plasma concentrations of clobazam and its main metabolite N-desmethyl-clobazam were measured by gas-chromatography. The area under the curve (AUC0−∞) of plasma clobazam level was significantly larger after pretreatment with cimetidine and the elimination half life of clobazam was significantly longer. There were no statistically significant differences in Cmax and tmax for plasma clobazam. The plasma levels of N-desmethyl-clobazam did not show any significant change after the intake of cimetidine.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00544031
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  • 8
    Electronic Resource
    Electronic Resource
    Pharmacodynamics and urine pharmacokinetics of three doses of piretanide (1983)
    Springer
    European journal of clinical pharmacology 25 (1983), S. 783-785 
    Details
    ISSN: 1432-1041
    Keywords: piretanide ; urine K+ and Na+ clearance ; pharmacodynamic effects ; pharmacokinetic effects ; diuretic effects ; dose-response relationship ; trial design
    Source: Springer Online Journal Archives 1860-2000
    Topics: Chemistry and Pharmacology , Medicine
    Notes: Summary Three doses (3 mg, 6 mg and 12 mg) of piretanide, a new high ceiling diuretic, and placebo were given to 8 volunteers to investigate the relationship between the pharmacodynamic parameters, the dose and its urinary excretion. Intake of food and fluid were standardized from 48 h before until 24 h after drug administration. Urinary output, excretion of unchanged drug, and the excretion and clearance of Na+ and K+ were measured hourly for 7 h after treatment. A clear dose-response relationship was found for cumulative urinary output, cumulative excretion of Na+ and K+, clearance of Na+ and K+ and the urinary sodium/potassium ratio. A significant correlation was found between the net urine volume and the excretion of piretanide per time interval. The clearances of Na+ and K+ were significantly correlated with the excretion of piretanide. Clearance values correlated well with corresponding urine volumes.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00542520
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  • 9
    Electronic Resource
    Electronic Resource
    Lack of interaction between ramipril and simvastatin (1994)
    Springer
    European journal of clinical pharmacology 47 (1994), S. 373-375 
    Details
    ISSN: 1432-1041
    Keywords: ACE-inhibitors ; Simvastatin ; ramipril ; lipid lowering drugs ; drug interaction ; pharmacokinetics
    Source: Springer Online Journal Archives 1860-2000
    Topics: Chemistry and Pharmacology , Medicine
    Notes: Abstract Twenty two healthy males participated in a randomised, placebo-controlled, double blind, cross-over study to investigate the influence of simvastatin on the pharmacokinetics of ramipril and its active metabolite (ramiprilat), and on the ACE-inhibiting effect of ramiprilat. During two study periods, each of 7 days, subjects received daily either simvastatin 20 mg at 19.00 h or placebo; ramipril (5 mg) was given on Day 5 of each of the periods. Plasma concentrations of ramipril and ramiprilat and ACE-activity were measured in sequential blood specimens, and ramipril and ramiprilat concentrations were measured in urine. Blood and urine collections for pharmacokinetic and pharmacodynamic assessment were made up to 72 h after the dose of ramipril. The mean AUC of ramipril for ramipril+placebo (R+P) and ramipril+simvastatin (R+S) was 22.2 and 21.3 ng.h.ml−, respectively; for ramiprilat the corresponding figures were 61.3 and 57.6 ng.h.ml−. The urinary excretion of ramipril+metabolites for (R+P) and (R+S) was 25.2 and 24.1% of dose. The maximum percentage inhibition of ACE-activity for (R+P) was 94.6%, and for (R+S) it was 94.1%. It is concluded that concomitant administration of simvastatin and ramipril has no clinically relevant effect on the pharmacokinetics or ACE-inhibition of the latter drug and its metabolites.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00191171
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  • 10
    Electronic Resource
    Electronic Resource
    Magnetische Messungen als Hilfsmittel der Fisenoxydbestimmung im Boden (1959)
    Springer
    Contributions to mineralogy and petrology 6 (1959), S. 371-387 
    Details
    ISSN: 1432-0967
    Source: Springer Online Journal Archives 1860-2000
    Topics: Geosciences
    Notes: Zusammenfassung Die Arbeit befaßt rich mit der Bestimmungsmöglichkeit der Eisenoxydmodifikationen in Böden — speziell des Lepidokrokits — mit Hilfe magnetischer Messungen. Einleitend wird ein Überblick über magnetische Grundgrößen und die Faktoren, die das ferromagnetische Verhalten beeinflussen, gegeben. Eine einfache Meßapparatur wird beschrieben and die Meßgenauigkeit diskutiert. Zur quantitativen Abschätzung von Lepidokrokitgehalten wird näher auf die Entstehung der Auftriebsgrößen, die Herstellung von Eichsubstanzen und die in Frage kommenden Umwandlungstemperaturen eingegangen. Für die Erhitzung von Böden wird eine Arbeitsmethode entwickelt. Ferner wird die dabei mögliche Entstehung ferromagnetischer Stoffe lurch anwesende organische Substanz behandelt. Die Grenzen and Möglichkeiten der Methode werden diskutiert und Beispiele von Messungen an Böden gebracht.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01206339
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