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  • Articles  (3)
  • Species Specificity  (3)
  • American Association for the Advancement of Science (AAAS)  (3)
  • American Chemical Society (ACS)
  • Chemistry and Pharmacology  (3)
  • Mathematics
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  • Articles  (3)
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  • American Association for the Advancement of Science (AAAS)  (3)
  • American Chemical Society (ACS)
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  • 1
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    BLyS: member of the tumor necrosis factor family and B lymphocyte stimulator (1999)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1999-07-10
    Description: The tumor necrosis factor (TNF) superfamily of cytokines includes both soluble and membrane-bound proteins that regulate immune responses. A member of the human TNF family, BLyS (B lymphocyte stimulator), was identified that induced B cell proliferation and immunoglobulin secretion. BLyS expression on human monocytes could be up-regulated by interferon-gamma. Soluble BLyS functioned as a potent B cell growth factor in costimulation assays. Administration of soluble recombinant BLyS to mice disrupted splenic B and T cell zones and resulted in elevated serum immunoglobulin concentrations. The B cell tropism of BLyS is consistent with its receptor expression on B-lineage cells. The biological profile of BLyS suggests it is involved in monocyte-driven B cell activation.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Moore, P A -- Belvedere, O -- Orr, A -- Pieri, K -- LaFleur, D W -- Feng, P -- Soppet, D -- Charters, M -- Gentz, R -- Parmelee, D -- Li, Y -- Galperina, O -- Giri, J -- Roschke, V -- Nardelli, B -- Carrell, J -- Sosnovtseva, S -- Greenfield, W -- Ruben, S M -- Olsen, H S -- Fikes, J -- Hilbert, D M -- New York, N.Y. -- Science. 1999 Jul 9;285(5425):260-3.〈br /〉〈span class="detail_caption"〉Author address: 〈/span〉Human Genome Sciences, 9410 Key West Avenue, Rockville, MD 20850, USA.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/10398604" target="_blank"〉PubMed〈/a〉
    Keywords: Amino Acid Sequence ; Animals ; B-Cell Activating Factor ; B-Cell Activation Factor Receptor ; B-Lymphocyte Subsets/immunology ; B-Lymphocytes/*immunology ; Cell Line ; Cells, Cultured ; Humans ; Immunoglobulins/blood ; Interferon-gamma/pharmacology ; *Lymphocyte Activation ; Membrane Proteins/chemistry/genetics/pharmacology/*physiology ; Mice ; Mice, Inbred BALB C ; Molecular Sequence Data ; Monocytes/*immunology ; Receptors, Cytokine/metabolism ; Receptors, Tumor Necrosis Factor/metabolism ; Recombinant Proteins/pharmacology ; Sequence Alignment ; Species Specificity ; Tumor Necrosis Factor-alpha/chemistry/genetics/pharmacology/*physiology ; Up-Regulation
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
    Published by American Association for the Advancement of Science (AAAS)
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  • 2
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    Transmission of equine influenza virus to dogs (2005)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 2005-09-28
    Description: Molecular and antigenic analyses of three influenza viruses isolated from outbreaks of severe respiratory disease in racing greyhounds revealed that they are closely related to H3N8 equine influenza virus. Phylogenetic analysis indicated that the canine influenza virus genomes form a monophyletic group, consistent with a single interspecies virus transfer. Molecular changes in the hemagglutinin suggested adaptive evolution in the new host. The etiologic role of this virus in respiratory disease was supported by the temporal association of rising antibody titers with disease and by experimental inoculation studies. The geographic expansion of the infection and its persistence for several years indicate efficient transmission of canine influenza virus among greyhounds. Evidence of infection in pet dogs suggests that this infection may also become enzootic in this population.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Crawford, P C -- Dubovi, Edward J -- Castleman, William L -- Stephenson, Iain -- Gibbs, E P J -- Chen, Limei -- Smith, Catherine -- Hill, Richard C -- Ferro, Pamela -- Pompey, Justine -- Bright, Rick A -- Medina, Marie-Jo -- Johnson, Calvin M -- Olsen, Christopher W -- Cox, Nancy J -- Klimov, Alexander I -- Katz, Jacqueline M -- Donis, Ruben O -- New York, N.Y. -- Science. 2005 Oct 21;310(5747):482-5. Epub 2005 Sep 26.〈br /〉〈span class="detail_caption"〉Author address: 〈/span〉College of Veterinary Medicine, University of Florida, Gainesville, FL 32611, USA.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/16186182" target="_blank"〉PubMed〈/a〉
    Keywords: Amino Acid Sequence ; Amino Acid Substitution ; Animals ; Antibodies, Viral/blood ; Cell Line ; Cytopathogenic Effect, Viral ; Disease Outbreaks/*veterinary ; Dog Diseases/epidemiology/pathology/*transmission/*virology ; Dogs ; Florida/epidemiology ; Hemagglutinin Glycoproteins, Influenza Virus/chemistry/genetics ; Horse Diseases/transmission/*virology ; Horses ; *Influenza A Virus, H3N8 Subtype/classification/immunology/isolation & ; purification/pathogenicity ; Molecular Sequence Data ; Orthomyxoviridae Infections/epidemiology/transmission/*veterinary/virology ; Phylogeny ; Respiratory System/pathology ; Sequence Analysis, RNA ; Species Specificity ; United States/epidemiology ; Virus Shedding
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
    Published by American Association for the Advancement of Science (AAAS)
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  • 3
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    Molecular phylogeny of the animal kingdom (1988)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1988-02-12
    Description: A rapid sequencing method for ribosomal RNA was applied to the resolution of evolutionary relationships among Metazoa. Representatives of 22 classes in 10 animal phyla were used to infer phylogenetic relationships, based on evolutionary distances determined from pairwise comparisons of the 18S ribosomal RNA sequences. The classical Eumetazoa are divided into two groups. Cnidarians arose from a protist ancestry different from the second group, the Bilateria. Within the Bilateria, an early split gave rise to Platyhelminthes (flatworms) and the coelomate lineage. Coelomates are thus monophyletic, and they radiated rapidly into four groups: chordates, echinoderms, arthropods, and eucoelomate protostomes.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Field, K G -- Olsen, G J -- Lane, D J -- Giovannoni, S J -- Ghiselin, M T -- Raff, E C -- Pace, N R -- Raff, R A -- GM34527/GM/NIGMS NIH HHS/ -- HD16739/HD/NICHD NIH HHS/ -- HD21337/HD/NICHD NIH HHS/ -- New York, N.Y. -- Science. 1988 Feb 12;239(4841 Pt 1):748-53.〈br /〉〈span class="detail_caption"〉Author address: 〈/span〉Institute for Molecular and Cellular Biology, Indiana University, Bloomington 47405.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/3277277" target="_blank"〉PubMed〈/a〉
    Keywords: Animals ; Biological Evolution ; Humans ; Invertebrates/*genetics ; *Phylogeny ; RNA, Ribosomal/*genetics ; RNA, Ribosomal, 18S/*genetics ; Species Specificity
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
    Published by American Association for the Advancement of Science (AAAS)
    Location Call Number Expected Availability
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